Cardiac Energy Metabolism in Health and Disease

Cardiac Energy Metabolism in Health and Disease
Author: Gary D. Lopaschuk,Naranjan S. Dhalla
Publsiher: Springer
Total Pages: 295
Release: 2014-08-22
ISBN 10: 1493912275
ISBN 13: 9781493912278
Language: EN, FR, DE, ES & NL

Cardiac Energy Metabolism in Health and Disease Book Review:

The heart has a very high energy demand but very little energy reserves. In order to sustain contractile function, the heart has to continually produce a large amount of ATP. The heart utilizes free fatty acids mainly and carbohydrates to some extent as substrates for making energy and any change in this energy supply can seriously compromise cardiac function. It has emerged that alterations in cardiac energy metabolism are a major contributor to the development of a number of different forms of heart disease. It is also now known that optimizing energy metabolism in the heart is a viable and important approach to treating various forms of heart disease. Cardiac Energy Metabolism in Health and Disease describes the research advances that have been made in understanding what controls cardiac energy metabolism at molecular, transcriptional and physiological levels. It also describes how alterations in energy metabolism contribute to the development of heart dysfunction and how optimization of energy metabolism can be used to treat heart disease. The topics covered include a discussion of the effects of myocardial ischemia, diabetes, obesity, hypertrophy, heart failure, and genetic disorders of mitochondrial oxidative metabolism on cardiac energetics. The treatment of heart disease by optimizing energy metabolism is also discussed, which includes increasing overall energy production as well as increasing the efficiency of energy production and switching energy substrate preference of the heart. This book will be a valuable source of information to graduate students, postdoctoral fellows, and investigators in the field of experimental cardiology as well as biochemists, physiologists, pharmacologists, cardiologists, cardiovascular surgeons and other health professionals.

The Scientist s Guide to Cardiac Metabolism

The Scientist s Guide to Cardiac Metabolism
Author: Michael Schwarzer,Torsten Doenst
Publsiher: Academic Press
Total Pages: 240
Release: 2015-11-04
ISBN 10: 0128026146
ISBN 13: 9780128026144
Language: EN, FR, DE, ES & NL

The Scientist s Guide to Cardiac Metabolism Book Review:

The Scientists Guide to Cardiac Metabolism combines the basic concepts of substrate metabolism, regulation, and interaction within the cell and the organism to provide a comprehensive introduction into the basics of cardiac metabolism. This important reference is the perfect tool for newcomers in cardiac metabolism, providing a basic understanding of the metabolic processes and enabling the newcomer to immediately communicate with the expert as substrate/energy metabolism becomes part of projects. The book is written by established experts in the field, bringing together all the concepts of cardiac metabolism, its regulation, and the impact of disease. Provides a quick and comprehensive introduction into cardiac metabolism Contains an integrated view on cardiac metabolism and its interrelation in metabolism with other organs Presents insights into substrate metabolism in relation to intracellular organization and structure as well as whole organ function Includes historical perspectives that reference important investigators that have contributed to the development of the field

Cardiac Energy Metabolism in Heart Failure

Cardiac Energy Metabolism in Heart Failure
Author: Society for Heart and Vascular Metabolism
Publsiher: Unknown
Total Pages: 135
Release: 2006
ISBN 10: 1928374650XXX
ISBN 13: OCLC:500541284
Language: EN, FR, DE, ES & NL

Cardiac Energy Metabolism in Heart Failure Book Review:

ATP and the Heart

ATP and the Heart
Author: Joanne S. Ingwall
Publsiher: Springer Science & Business Media
Total Pages: 244
Release: 2012-12-06
ISBN 10: 1461510937
ISBN 13: 9781461510932
Language: EN, FR, DE, ES & NL

ATP and the Heart Book Review:

ATP plays a central role in the two leading causes of cardiac morbidity and mortality in the western world: ischemia and heart failure. We are in our infancy applying what is known about biology and chemistry of ATP toward developing effective therapies for these diseases. In this volume, the current understanding of the chemistry and biology of ATP specifically in the cardiomyocyte is presented. New insights into ATP have been gleaned using biophysical techniques allowing dynamic measurement of chemical events in the intact beating heart and using new animal models in which cardiac proteins are either over expressed, deleted or harbor specific mutations. This book provides a summary of the basic understanding and includes illustrations of why ATP and the Heart is important to both the clinician and scientist.

Oxford Textbook of Heart Failure

Oxford Textbook of Heart Failure
Author: Roy S. Gardner,Andrew L. Clark,Henry Dargie
Publsiher: Oxford University Press
Total Pages: 641
Release: 2011-07-14
ISBN 10: 0199577722
ISBN 13: 9780199577729
Language: EN, FR, DE, ES & NL

Oxford Textbook of Heart Failure Book Review:

Written by internationally renowned leaders in their field and relevant to all practicing clinicians, this textbook comprehensively covers all aspects of heart failure, and suggests the optimal evidence-based management for heart failure patients.

Metabolic Cardiomyopathy

Metabolic Cardiomyopathy
Author: H. Böhles,A. C. Sewell
Publsiher: CRC Press
Total Pages: 188
Release: 2004
ISBN 10: 9783887631048
ISBN 13: 3887631048
Language: EN, FR, DE, ES & NL

Metabolic Cardiomyopathy Book Review:

During the last years the understanding for the aetiology of cardiomyopathies could be greatly improved. A great deal of information has accumulated in the field of inherited metabolic diseases, which provides a new basis for our understanding of many heart muscle problems and their corresponding clinical disease entities. This book is meant to give the reader a comprehensive overview of the cardiological manifestations of inborn errors of metabolism. Latest information, such as cardiomyopathy in Fabry disease or in patients with CDG-syndrome is included. It should be helpful, not only to cardiologists, paediatricians, internists and general practicioners, but also to all those interested in a better understanding of the metabolic basis of clinical disease entities.

Novel Concepts in Cardiac Energy Metabolism From Biology to Disease

Novel Concepts in Cardiac Energy Metabolism  From Biology to Disease
Author: Thomas Pulinilkunnil,Petra Kienesberger,Jeevan Nagendran
Publsiher: Frontiers Media SA
Total Pages: 89
Release: 2019-08-08
ISBN 10: 2889459381
ISBN 13: 9782889459384
Language: EN, FR, DE, ES & NL

Novel Concepts in Cardiac Energy Metabolism From Biology to Disease Book Review:

Special Issue

Special Issue
Author: William C. Stanley
Publsiher: Unknown
Total Pages: 135
Release: 2002
ISBN 10: 1928374650XXX
ISBN 13: OCLC:64397329
Language: EN, FR, DE, ES & NL

Special Issue Book Review:

The Sinatra Solution

The Sinatra Solution
Author: Stephen T. Sinatra, M.D.
Publsiher: ReadHowYouWant.com
Total Pages: 564
Release: 2009-04-24
ISBN 10: 1442975032
ISBN 13: 9781442975033
Language: EN, FR, DE, ES & NL

The Sinatra Solution Book Review:

Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and D-ribose in the body and specifically how they affect your heart health. He also provides concise and informative examples of case histories and scientific studies that are testament to the important contribution the supplemental use of these energy-supplying nutrients make in the lives of people with heart disease every day.

Obesity and Diabetes Mellitus

Obesity and Diabetes Mellitus
Author: E. I. Sokolov
Publsiher: CRC Press
Total Pages: 290
Release: 2020-08-14
ISBN 10: 1000152790
ISBN 13: 9781000152791
Language: EN, FR, DE, ES & NL

Obesity and Diabetes Mellitus Book Review:

This book is the result of the study of metabolic and hormonal disorders in patients suffering obesity and diabetes mellitus, focusing on mechanisms of formation of atherosclerotic changes in the myocardium and vessels in diabetes mellitus patient.

The Sinatra Solution

The Sinatra Solution
Author: Stephen T. Sinatra, M.D.
Publsiher: ReadHowYouWant.com
Total Pages: 460
Release: 2009-04-24
ISBN 10: 1442975024
ISBN 13: 9781442975026
Language: EN, FR, DE, ES & NL

The Sinatra Solution Book Review:

Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and D-ribose in the body and specifically how they affect your heart health. He also provides concise and informative examples of case histories and scientific studies that are testament to the important contribution the supplemental use of these energy-supplying nutrients make in the lives of people with heart disease every day.

Cardiac Energetics

Cardiac Energetics
Author: R. Jacob,Hanjoerg Just,C. Holubarsch
Publsiher: Springer Science & Business Media
Total Pages: 425
Release: 2013-04-17
ISBN 10: 3662112892
ISBN 13: 9783662112892
Language: EN, FR, DE, ES & NL

Cardiac Energetics Book Review:

Assessment of cardiac energetics at the level of ATP-synthesis, chemomechanical energy transformation and whole organ dynamics as a function of haemodynamic load, ventricular configuration and oxygen- and substrates supply is basic to understanding cardiac function under physiological and pathophysiological (hypertrophy, hypoxia, ischaemia and heart failure) conditions. Moreover, cardiac energetics should be an important consideration in the choice and application of drugs especially in the case of vasodilators, inotropic agents and in cardioprotective measures. Only by considering energetics at the subcellular, cellular, and whole-heart level we can arrive at a better understanding of cardiac performance and ultimately better clinical judgement and drug therapy. Quantification of myocardial energetics will also help to determine the optimal time for surgical interventions such as valvular replacement or aneurysm resection. The present volume is the outcome of an international symposium on cardiac energetics held in Gargellen/Montafon (Austria), June 1986. The contributions will certainly help bridge the existing gap between basic research involving isolated structures and that involving the whole organ, on the one hand, and render the results derived from basic research applicable to clinical problems, on the other hand.

Myocardial Energy Metabolism

Myocardial Energy Metabolism
Author: J.W. de Jong
Publsiher: Springer Science & Business Media
Total Pages: 310
Release: 2012-12-06
ISBN 10: 9400913192
ISBN 13: 9789400913196
Language: EN, FR, DE, ES & NL

Myocardial Energy Metabolism Book Review:

The Sinatra Solution

The Sinatra Solution
Author: Stephen T. Sinatra, M.D.
Publsiher: ReadHowYouWant.com
Total Pages: 308
Release: 2009-04-24
ISBN 10: 1442975059
ISBN 13: 9781442975057
Language: EN, FR, DE, ES & NL

The Sinatra Solution Book Review:

Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and D-ribose in the body and specifically how they affect your heart health. He also provides concise and informative examples of case histories and scientific studies that are testament to the important contribution the supplemental use of these energy-supplying nutrients make in the lives of people with heart disease every day.

The Sinatra Solution

The Sinatra Solution
Author: Stephen T. Sinatra, M.D.
Publsiher: ReadHowYouWant.com
Total Pages: 380
Release: 2009-04-24
ISBN 10: 1442975075
ISBN 13: 9781442975071
Language: EN, FR, DE, ES & NL

The Sinatra Solution Book Review:

Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and D-ribose in the body and specifically how they affect your heart health. He also provides concise and informative examples of case histories and scientific studies that are testament to the important contribution the supplemental use of these energy-supplying nutrients make in the lives of people with heart disease every day.

The Sinatra Solution

The Sinatra Solution
Author: Stephen T. Sinatra, M.D.
Publsiher: ReadHowYouWant.com
Total Pages: 512
Release: 2009-04-24
ISBN 10: 1442975016
ISBN 13: 9781442975019
Language: EN, FR, DE, ES & NL

The Sinatra Solution Book Review:

Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and D-ribose in the body and specifically how they affect your heart health. He also provides concise and informative examples of case histories and scientific studies that are testament to the important contribution the supplemental use of these energy-supplying nutrients make in the lives of people with heart disease every day.

Cancer as a Metabolic Disease

Cancer as a Metabolic Disease
Author: Thomas Seyfried
Publsiher: John Wiley & Sons
Total Pages: 448
Release: 2012-05-18
ISBN 10: 1118310306
ISBN 13: 9781118310304
Language: EN, FR, DE, ES & NL

Cancer as a Metabolic Disease Book Review:

The book addresses controversies related to the origins of cancer and provides solutions to cancer management and prevention. It expands upon Otto Warburg's well-known theory that all cancer is a disease of energy metabolism. However, Warburg did not link his theory to the "hallmarks of cancer" and thus his theory was discredited. This book aims to provide evidence, through case studies, that cancer is primarily a metabolic disease requring metabolic solutions for its management and prevention. Support for this position is derived from critical assessment of current cancer theories. Brain cancer case studies are presented as a proof of principle for metabolic solutions to disease management, but similarities are drawn to other types of cancer, including breast and colon, due to the same cellular mutations that they demonstrate.

Biophysics of the Failing Heart

Biophysics of the Failing Heart
Author: R. John Solaro,Jil C. Tardiff
Publsiher: Springer Science & Business Media
Total Pages: 253
Release: 2013-08-13
ISBN 10: 146147678X
ISBN 13: 9781461476788
Language: EN, FR, DE, ES & NL

Biophysics of the Failing Heart Book Review:

Subjects in the monograph “Biophysics of the Failing Heart” include state of the art chapters considering major biophysical mechanisms for why hearts responding to acquired or inherited stressors enter into maladaptive processes eventually leading to an inability of the heart to respond efficiently to hemodynamic loads especially during exercise. The chapters describe biophysical techniques that have been applied to determine the triggers for the heart failure process as well as the mechanisms for sustaining the disorders. These techniques include measurements of active and passive mechanical properties and hemodynamics at levels of organization ranging from molecules to hearts beating in situ. Biophysical concepts and approaches are also applied to determination of signaling and signal transduction, energetics, ionic currents, transport processes, electro-chemical and chemo-mechanical coupling. By its emphasis on biophysical aspects of a prevalent clinical condition, the monograph is unique in its perspective and focus. The breadth of information in the chapters all in one place will be of value to clinicians and researchers at all levels. Modern research approaches and clinical understanding of heart failure demands integration of multiple aspects of the disorders. In most cases, combinations of clinician scientists and researchers author the chapters. A main benefit of the book is couched in its didactic approach together with its emphasis on how biophysical concepts and techniques aid in diagnosis and development of new therapies.

Inflammation in Heart Failure

Inflammation in Heart Failure
Author: Matthijs Blankesteijn,Raffaele Altara
Publsiher: Academic Press
Total Pages: 220
Release: 2014-12-05
ISBN 10: 0128004851
ISBN 13: 9780128004852
Language: EN, FR, DE, ES & NL

Inflammation in Heart Failure Book Review:

Inflammation in Heart Failure, edited by W. Matthijs Blankesteijn and Raffaele Altara, is the first book in a decade to provide an in-depth assessment on the causes, symptoms, progression and treatments of cardiac inflammation and related conditions. This reference uses two decades of research to introduce new methods for identifying inflammatory benchmarks from early onset to chronic heart failure and specifically emphasizes the importance of classifying at-risk subgroups within large populations while determining the patterns of cytokines in such classifications. Further, the book details clinical applications of the pathophysiological mechanisms of heart failure, diagnosis and therapeutic strategies. Inflammation in Heart Failure’s breadth of subject matter, easy-to-follow structure, portability, and high-quality illustrations create an accessible benefit for researchers, clinicians and students. Presents updated information and research on the relevant inflammatory mediators of heart failure to aid in targeting future translational research as well as the improvement of early diagnosis and treatment Provides research into better understanding the different inflammatory mediators that signal the underlying diseases that potentially lead to heart failure Contains 20 years of research, offering a brief overview of the topic leading to current opinions on, and treatment of, heart failure Provides a structured, systematic and balanced overview of the role of inflammation in heart failure making it a useful resource for researchers and clinicians, as well as those studying cardiovascular diseases

The Sinatra Solution

The Sinatra Solution
Author: Stephen T. Sinatra, M.D.
Publsiher: ReadHowYouWant.com
Total Pages: 520
Release: 2009-04-24
ISBN 10: 1442975261
ISBN 13: 9781442975262
Language: EN, FR, DE, ES & NL

The Sinatra Solution Book Review:

Board-certified cardiologist Dr. Stephen T. Sinatra discusses the importance of energy metabolism on cardiovascular health and the positive impact these three energy-supplying nutrients have on the cardiovascular system. He guides you through the basics of energy metabolism and cardiac bioenergetics, and clearly explains the role of coenzyme Q10, L-carnitine, and D-ribose in the body and specifically how they affect your heart health. He also provides concise and informative examples of case histories and scientific studies that are testament to the important contribution the supplemental use of these energy-supplying nutrients make in the lives of people with heart disease every day.