Computer Aided Applications in Pharmaceutical Technology

Computer Aided Applications in Pharmaceutical Technology
Author: Jelena Djuris
Publsiher: Elsevier
Total Pages: 300
Release: 2013-04-10
ISBN 10: 1908818328
ISBN 13: 9781908818324
Language: EN, FR, DE, ES & NL

Computer Aided Applications in Pharmaceutical Technology Book Review:

Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-aided applications in pharmaceutical technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology. A comprehensive review of the current state of the art on various computer aided applications in pharmaceutical technology Case studies are presented in order to facilitate understanding of various concepts in computer-aided applications

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
Author: Ljiljana Djekic,Dragana Vasiljevic,Marija Primorac
Publsiher: Elsevier Inc. Chapters
Total Pages: 300
Release: 2013-04-10
ISBN 10: 0128091886
ISBN 13: 9780128091883
Language: EN, FR, DE, ES & NL

Computer aided applications in pharmaceutical technology Book Review:

This chapter introduces the concept of formulation development assisted by computer applications. Development and optimization of various types of pharmaceutical emulsions microemulsions, self-microemulsifying systems, and double emulsions are presented. Illustrative examples are presented to demonstrate the ability of computer-aided tools to facilitate formulation development. Various techniques, such as design of experiments and artificial neural networks, are implemented for optimization of the formulation and/or processing parameters. Furthermore, some of the critical quality attributes and processing parameters are optimized simultaneously. The examples presented should serve as the foundation for the future quality-by-design development of pharmaceutical emulsion and (self) microemulsion formulations.

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
Author: Jelena Djuris,Svetlana Ibric,Zorica Djuric
Publsiher: Elsevier Inc. Chapters
Total Pages: 300
Release: 2013-04-10
ISBN 10: 0128091878
ISBN 13: 9780128091876
Language: EN, FR, DE, ES & NL

Computer aided applications in pharmaceutical technology Book Review:

This first chapter introduces the concept of quality-by-design (QbD) and its role in pharmaceutical product development. QbD assures the quality of a pharmaceutical product through scientific development and risk management tools, and will eventually enable real-time release, regardless of the formulation type. Several guidelines on pharmaceutical development, quality risk management, and pharmaceutical quality systems are presented that are applicable throughout the product lifecycle. Design space appointment and control strategies for risk management are introduced. The meaning of the QbD concept is presented from both regulatory and manufacturers’ points of view. Several illustrative examples are provided to facilitate the understanding of the QbD concept and ease of its application.

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
Author: Ivana Masic,Jelena Parojcic,Zorica Djuric
Publsiher: Elsevier Inc. Chapters
Total Pages: 300
Release: 2013-04-10
ISBN 10: 0128091932
ISBN 13: 9780128091937
Language: EN, FR, DE, ES & NL

Computer aided applications in pharmaceutical technology Book Review:

This chapter introduces the concept of computational fluid dynamics (CFD) and its applications in pharmaceutical technology. Basic theoretical explanations on the mathematics of fluid flow and numerical grids are provided. CFD is a versatile tool that is mainly used in complex dynamical process characterization. Examples of CFD applications in development of inhalers, analysis of dissolution apparatus hydrodynamics, and fluidized bed process simulations are presented.

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
Author: Jelena Djuris,Svetlana Ibric,Zorica Djuric
Publsiher: Elsevier Inc. Chapters
Total Pages: 300
Release: 2013-04-10
ISBN 10: 0128091894
ISBN 13: 9780128091890
Language: EN, FR, DE, ES & NL

Computer aided applications in pharmaceutical technology Book Review:

This chapter provides a basic theoretical background on experimental design application and interpretation. Techniques described include screening designs, full and fractional factorial designs, Plackett–Burman design, D-optimal designs, response surface methodology, central composite designs, Box–Behnken design, and mixture designs, etc. The reader will be introduced to the experimental domains covered by specific design, making it easier to select the one appropriate for the problem. After theoretical introduction, a number of illustrative examples of design of experiments application in the field of pharmaceutical technology are presented.

Computer aided applications in pharmaceutical technology

Computer aided applications in pharmaceutical technology
Author: Sandra Grbic,Jelena Parojcic,Zorica Djuric
Publsiher: Elsevier Inc. Chapters
Total Pages: 300
Release: 2013-04-10
ISBN 10: 0128091924
ISBN 13: 9780128091920
Language: EN, FR, DE, ES & NL

Computer aided applications in pharmaceutical technology Book Review:

This chapter introduces the concept of gastrointestinal absorption simulation using in silico methodology. Parameters used for model construction and the sensitivity predicted pharmacokinetic responses to various input parameters are described. Virtual trials for in silico modeling of drug absorption are presented. The influence of food on drug absorption, as well as correlation between the in vitro and in vivo results, are also addressed, followed by biowaiver considerations. Numerous examples are provided throughout the chapter.

Computer Applications in Pharmaceutical Science

Computer Applications in Pharmaceutical Science
Author: S. L. Lim
Publsiher: Unknown
Total Pages: 135
Release: 2019-09-19
ISBN 10: 9781645321095
ISBN 13: 1645321096
Language: EN, FR, DE, ES & NL

Computer Applications in Pharmaceutical Science Book Review:

Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-aided applications in pharmaceutical technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing. It explains how applications are used at various stages. The book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.

Computer Aided Pharmaceutics and Drug Delivery

Computer Aided Pharmaceutics and Drug Delivery
Author: Vikas Anand Saharan
Publsiher: Springer Nature
Total Pages: 762
Release: 2022-05-30
ISBN 10: 9811651809
ISBN 13: 9789811651809
Language: EN, FR, DE, ES & NL

Computer Aided Pharmaceutics and Drug Delivery Book Review:

This book examines the role of computer-assisted techniques for discovering, designing, optimizing and manufacturing new, effective, and safe pharmaceutical formulations and drug delivery systems. The book discusses computational approaches, statistical modeling and molecular modeling for the development and safe delivery of drugs in humans. The application of concepts of QbD (Quality by Design), DoE (Design of Experiments), artificial intelligence and in silico pharmacokinetic assessment/simulation have been made a lot easier with the help of commercial software and expert systems. This title provides in-depth knowledge of such useful software with illustrations from the latest researches. The book also fills in the gap between pharmaceutics and molecular modeling at micro, meso and maro scale by covering topics such as advancements in computer-aided Drug Design (CADD), drug-polymer interactions in drug delivery systems, molecular modeling of nanoparticles and pharmaceutics/bioinformatics. This book provides abundant applications of computers in formulation designing and characterization are provided as examples, case studies and illustrations. Short reviews of software, databases and expert systems have also been added to culminate the interest of readers for novel applications in formulation development and drug delivery. Computer-aided pharmaceutics and drug delivery is an authoritative reference source for all the latest scholarly update on emerging developments in computed assisted techniques for drug designing and development. The book is ideally designed for pharmacists, medical practitioners, students and researchers.

Computer Applications in Pharmaceutical Research and Development

Computer Applications in Pharmaceutical Research and Development
Author: Sean Ekins
Publsiher: John Wiley & Sons
Total Pages: 805
Release: 2006-07-11
ISBN 10: 0470037229
ISBN 13: 9780470037225
Language: EN, FR, DE, ES & NL

Computer Applications in Pharmaceutical Research and Development Book Review:

A unique, holistic approach covering all functions and phases of pharmaceutical research and development While there are a number of texts dedicated to individual aspects of pharmaceutical research and development, this unique contributed work takes a holistic and integrative approach to the use of computers in all phases of drug discovery, development, and marketing. It explains how applications are used at various stages, including bioinformatics, data mining, predicting human response to drugs, and high-throughput screening. By providing a comprehensive view, the book offers readers a unique framework and systems perspective from which they can devise strategies to thoroughly exploit the use of computers in their organizations during all phases of the discovery and development process. Chapters are organized into the following sections: * Computers in pharmaceutical research and development: a general overview * Understanding diseases: mining complex systems for knowledge * Scientific information handling and enhancing productivity * Computers in drug discovery * Computers in preclinical development * Computers in development decision making, economics, and market analysis * Computers in clinical development * Future applications and future development Each chapter is written by one or more leading experts in the field and carefully edited to ensure a consistent structure and approach throughout the book. Figures are used extensively to illustrate complex concepts and multifaceted processes. References are provided in each chapter to enable readers to continue investigating a particular topic in depth. Finally, tables of software resources are provided in many of the chapters. This is essential reading for IT professionals and scientists in the pharmaceutical industry as well as researchers involved in informatics and ADMET, drug discovery, and technology development. The book's cross-functional, all-phases approach provides a unique opportunity for a holistic analysis and assessment of computer applications in pharmaceutics.

Computer Aided Vaccine Design

Computer Aided Vaccine Design
Author: Joo Chuan Tong,Shoba Ranganathan
Publsiher: Elsevier
Total Pages: 164
Release: 2013-07-31
ISBN 10: 1908818417
ISBN 13: 9781908818416
Language: EN, FR, DE, ES & NL

Computer Aided Vaccine Design Book Review:

Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics. Essential reading for any biologist who wants to understand methods of computer-aided vaccine design Description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses Theoretical concepts and practical examples of database design and development for a virtual screening campaign

An Introduction to Pharmaceutical Sciences

An Introduction to Pharmaceutical Sciences
Author: Jiben Roy
Publsiher: Elsevier
Total Pages: 446
Release: 2011-07-25
ISBN 10: 1908818042
ISBN 13: 9781908818041
Language: EN, FR, DE, ES & NL

An Introduction to Pharmaceutical Sciences Book Review:

This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences. This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry. A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial processes Covers many aspects relevant to students of the pharmaceutical sciences or newly employed pharmaceutical researchers/employees. It contains summary information about regulatory agencies of different countries

Sterility Sterilisation and Sterility Assurance for Pharmaceuticals

Sterility  Sterilisation and Sterility Assurance for Pharmaceuticals
Author: Tim Sandle
Publsiher: Elsevier
Total Pages: 362
Release: 2013-10-31
ISBN 10: 1908818638
ISBN 13: 9781908818638
Language: EN, FR, DE, ES & NL

Sterility Sterilisation and Sterility Assurance for Pharmaceuticals Book Review:

Failure to adequately control any microbial challenge associated within process or product by robust sterilisation will result in a contaminated marketed product, with potential harm to the patient. Sterilisation is therefore of great importance to healthcare and the manufacturers of medical devices and pharmaceuticals. Sterility, sterilisation and sterility assurance for pharmaceuticals examines different means of rendering a product sterile by providing an overview of sterilisation methods including heat, radiation and filtration. The book outlines and discusses sterilisation technology and the biopharmaceutical manufacturing process, including aseptic filling, as well as aspects of the design of containers and packaging, as well as addressing the cleanroom environments in which products are prepared. Consisting of 18 chapters, the book comprehensively covers sterility, sterilisation and microorganisms; pyrogenicity and bacterial endotoxins; regulatory requirements and good manufacturing practices; and gamma radiation. Later chapters discuss e-beam; dry heat sterilisation; steam sterilisation; sterilisation by gas; vapour sterilisation; and sterile filtration, before final chapters analyse depyrogenation; cleanrooms; aseptic processing; media simulation; biological indicators; sterility testing; auditing; and new sterilisation techniques. Covers the main sterilisation methods of physical removal, physical alteration and inactivation Includes discussion of medical devices, aseptically filled products and terminally sterilised products Describes bacterial, pyrogenic, and endotoxin risks to devices and products

Bioinformatics for Biomedical Science and Clinical Applications

Bioinformatics for Biomedical Science and Clinical Applications
Author: K-H Liang
Publsiher: Elsevier
Total Pages: 170
Release: 2013-07-31
ISBN 10: 1908818239
ISBN 13: 9781908818232
Language: EN, FR, DE, ES & NL

Bioinformatics for Biomedical Science and Clinical Applications Book Review:

Contemporary biomedical and clinical research is undergoing constant development thanks to the rapid advancement of various high throughput technologies at the DNA, RNA and protein levels. These technologies can generate vast amounts of raw data, making bioinformatics methodologies essential in their use for basic biomedical and clinical applications. Bioinformatics for biomedical science and clinical applications demonstrates what these cutting-edge technologies can do and examines how to design an appropriate study, including how to deal with data and address specific clinical questions. The first two chapters consider Bioinformatics and analysis of the human genome. The subsequent three chapters cover the introduction of Transcriptomics, Proteomics and Systems biomedical science. The remaining chapters move on to critical developments, clinical information and conclude with domain knowledge and adaptivity. A coherent presentation of concepts, methodologies and practical tools that systematically lead to significant discoveries in the biomedical and clinical area Real examples of cutting edge discoveries The introduction of study types and technologies for all the DNA, RNA and protein levels

Formulation tools for Pharmaceutical Development

Formulation tools for Pharmaceutical Development
Author: J E Aguilar
Publsiher: Elsevier
Total Pages: 304
Release: 2013-09-30
ISBN 10: 1908818506
ISBN 13: 9781908818508
Language: EN, FR, DE, ES & NL

Formulation tools for Pharmaceutical Development Book Review:

A range of new and innovative tools used for preformulation and formulation of medicines help optimize pharmaceutical development projects. Such tools also assist with the performance evaluation of the pharmaceutical process, allowing any potential gaps to be identified. These tools can be applied in both basic research and industrial environment. Formulation tools for pharmaceutical development considers these key research and industrial tools. Nine chapters by leading contributors cover: Artificial neural networks technology to model, understand, and optimize drug formulations; ME_expert 2.0: a heuristic decision support system for microemulsions formulation development; Expert system for the development and formulation of push-pull osmotic pump tablets containing poorly water-soluble drugs; SeDeM Diagram: an expert system for preformulation, characterization and optimization of tables obtained by direct compression; New SeDeM-ODT expert system: an expert system for formulation of orodispersible tablets obtained by direct compression; and 3D-cellular automata in computer-aided design of pharmaceutical formulations: mathematical concept and F-CAD software. Coverage of artificial intelligence tools, new expert systems, understanding of pharmaceutical processes, robust development of medicines, and new ways to develop medicines Development of drugs and medicines using mathematical tools Compilation of expert system developed around the world

Commercializing the Stem Cell Sciences

Commercializing the Stem Cell Sciences
Author: Olivia Harvey
Publsiher: Elsevier
Total Pages: 212
Release: 2012-10-16
ISBN 10: 190881814X
ISBN 13: 9781908818140
Language: EN, FR, DE, ES & NL

Commercializing the Stem Cell Sciences Book Review:

Promising new developments in biomedical technology such as stem cell science are widely endorsed by governments keen to reduce spiralling healthcare costs, clinicians focused on patient care, and patients demanding revolutionary new treatments. Commercializing the stem cell sciences offers a comparative analysis of the commercial methods adopted in the global stem cell industries. It seeks to establish whether there is an optimum commercial model and to examine what emerging companies can learn from their predecessors. Following an introduction to stem cell sciences and the problems involved in their commercialization, the book begins with a discussion of stem cell treatments from a global perspective, and the role of innovation in the commercialization of biotechnology in general. In the second half of the book, chapters focus on the different strategies that can be employed and their relative risks and values, before a conclusion that looks at potential new developments in the field. In-depth discussion of case studies of products undergoing development Focus on commercial optimization of stem cell treatments Analysis in a global context and covering a diverse range of countries

Microsized and Nanosized Carriers for Nonsteroidal Anti Inflammatory Drugs

Microsized and Nanosized Carriers for Nonsteroidal Anti Inflammatory Drugs
Author: Bojan Čalija
Publsiher: Academic Press
Total Pages: 284
Release: 2017-01-03
ISBN 10: 0128040807
ISBN 13: 9780128040805
Language: EN, FR, DE, ES & NL

Microsized and Nanosized Carriers for Nonsteroidal Anti Inflammatory Drugs Book Review:

Microsized and Nanosized Carriers for Nonsteroidal Anti-Inflammatory Drugs: Formulation Challenges and Potential Benefits provides a unique and complete overview of novel formulation strategies for improvement of the delivery of NSAIDs via encapsulation in microsized and nanosized carriers composed of different materials of natural and synthetic origin. This book presents the latest research on advances and limitations of both microsized and nanosized drug carriers and NSAIDs before discussing the formulation aspects of these drug carriers that are intended for oral, dermal, and transdermal administration of NSAIDs. In addition, functionality of these materials as potential excipients for microsized and nanosized carriers is discussed and debated. Practical solutions for improving effectiveness of these drugs are included throughout the book, making this an important resource for graduate students, professors, and researchers in the pharmaceutical sciences. Covers a wide range of microsized and nanosized carriers in one resource, including particulate carriers (microparticles, nanoparticles, and zeolites) and the soft colloidal carriers, such as micro-emulsions and nano-emulsions Presents the reader with various formulation approaches dependent on the characteristics of the material, model drug, and desired route of administration Approaches are based on the latest research in the area and formulation strategies may have broader applications to the encapsulation of other active pharmaceutical ingredients

Release and Bioavailability of Nanoencapsulated Food Ingredients

Release and Bioavailability of Nanoencapsulated Food Ingredients
Author: Anonim
Publsiher: Academic Press
Total Pages: 508
Release: 2020-06-02
ISBN 10: 012815666X
ISBN 13: 9780128156667
Language: EN, FR, DE, ES & NL

Release and Bioavailability of Nanoencapsulated Food Ingredients Book Review:

Release and Bioavailability of Nanoencapsulated Food Ingredients, volume five in the Nanoencapsulation in the Food Industry series, reviews different release mechanisms of nanoencapsulated food ingredients. The book discusses mathematical and intelligent modeling of the release of bioactive agents from nano-vehicles to better understand their release mechanisms, while also covering different approaches for studying the release profile of these ingredients (such as in-vitro and in-vivo assays). Authored by a team of global experts in the fields of nano and microencapsulation of food, nutraceutical and pharmaceutical ingredients, this title will be of great value to those engaged in various fields of nanoencapsulation. Thoroughly explores the different release mechanisms of nanoencapsulated food ingredients Examines the release of bioactive ingredients by in vitro and in vivo systems Discusses different approaches for modeling the release data of nanoencapsulated ingredients

Molecular Docking for Computer Aided Drug Design

Molecular Docking for Computer Aided Drug Design
Author: S. Mohane Coumar
Publsiher: Academic Press
Total Pages: 520
Release: 2021-02-17
ISBN 10: 0128223138
ISBN 13: 9780128223130
Language: EN, FR, DE, ES & NL

Molecular Docking for Computer Aided Drug Design Book Review:

Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved in drug design and discovery. Covers the latest information and state-of-the-art trends in structure-based drug design methodologies Includes case studies that complement learning Consolidates fundamental concepts and current practice of molecular docking into one convenient resource

Computer Aided Drug Design and Delivery Systems

Computer Aided Drug Design and Delivery Systems
Author: Ahindra Nag,Baishakhi Dey
Publsiher: McGraw Hill Professional
Total Pages: 240
Release: 2010-10-06
ISBN 10: 0071701257
ISBN 13: 9780071701259
Language: EN, FR, DE, ES & NL

Computer Aided Drug Design and Delivery Systems Book Review:

THE LATEST BREAKTHROUGHS IN COMPUTER-AIDED DRUG DESIGN AND DELIVERY This definitive text provides in-depth information on computer-assisted techniques for discovering, designing, and optimizing new, effective, and safe drugs. Computer-Aided Drug Design and Delivery Systems offers objective and quantitative data on the use and delivery of drugs in humans. Enabling technologies such as bioinformatics, pharmacokinetics, biosensors, robotics, and bioinstruments are thoroughly discussed in this innovative work. Coverage includes: Computer-aided drug design (CADD) Drug delivery systems Bioinformatics of drug molecules and databases Lipase- and esterase-mediated drugs and drug intermediates Pharmacokinetics and pharmacodynamics of drugs Biomarkers, biosensors, and robotics in medicine Biomedical instrumentation

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment
Author: Kunal Roy,Supratik Kar,Rudra Narayan Das
Publsiher: Academic Press
Total Pages: 484
Release: 2015-03-03
ISBN 10: 0128016337
ISBN 13: 9780128016336
Language: EN, FR, DE, ES & NL

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment Book Review:

Understanding the Basics of QSAR for Applications in Pharmaceutical Sciences and Risk Assessment describes the historical evolution of quantitative structure-activity relationship (QSAR) approaches and their fundamental principles. This book includes clear, introductory coverage of the statistical methods applied in QSAR and new QSAR techniques, such as HQSAR and G-QSAR. Containing real-world examples that illustrate important methodologies, this book identifies QSAR as a valuable tool for many different applications, including drug discovery, predictive toxicology and risk assessment. Written in a straightforward and engaging manner, this is the ideal resource for all those looking for general and practical knowledge of QSAR methods. Includes numerous practical examples related to QSAR methods and applications Follows the Organization for Economic Co-operation and Development principles for QSAR model development Discusses related techniques such as structure-based design and the combination of structure- and ligand-based design tools