Biochemical Analysis Tools

Biochemical Analysis Tools
Author: Oana-Maria Boldura,Cornel Balta,Prof Nasser Awwad
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2020-06-24
ISBN 10: 1789848563
ISBN 13: 9781789848564
Language: EN, FR, DE, ES & NL

Biochemical Analysis Tools Book Review:

This book explores the role of nucleic acid analysis and the advances it has led to in the field of life sciences. The first section is a collection of chapters covering experimental methods used in molecular biology, the techniques adjacent to these methods, and the steps of analysis before and after obtaining raw DNA data. The second section deals with the principles of chromatography, method development, sample preparation, and industrial applications.

HPLC for Pharmaceutical Scientists

HPLC for Pharmaceutical Scientists
Author: Yuri V. Kazakevich,Rosario LoBrutto
Publsiher: John Wiley & Sons
Total Pages: 1080
Release: 2007-02-16
ISBN 10: 0470087943
ISBN 13: 9780470087947
Language: EN, FR, DE, ES & NL

HPLC for Pharmaceutical Scientists Book Review:

HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.

Handbook of Pharmaceutical Analysis

Handbook of Pharmaceutical Analysis
Author: Lena Ohannesian,Anthony Streeter
Publsiher: CRC Press
Total Pages: 608
Release: 2001-11-09
ISBN 10: 0824741943
ISBN 13: 9780824741945
Language: EN, FR, DE, ES & NL

Handbook of Pharmaceutical Analysis Book Review:

Exploring the analysis of pharmaceuticals, including polymorphic forms, this book discusses regulatory requirements in pharmaceutical product development and pharmaceutical testing. It covers methods of drug separation and procedures such as capillary electrophoresis for chromatographic separation of molecules. Additional topics include drug formulation analysis using vibrational and magnetic resonance spectroscopy and identification of drug metabolites and decomposition products using such techniques as mass spectrometry. The book provides more than 300 tables, equations, drawings, and photographs, and convenient, easy-to-use indices, facilitating quick access to each topic.

Promising Drug Molecules of Natural Origin

Promising Drug Molecules of Natural Origin
Author: Rohit Dutt,Anil K. Sharma,Raj K. Keservani,Vandana Garg
Publsiher: CRC Press
Total Pages: 458
Release: 2020-11-04
ISBN 10: 1000765156
ISBN 13: 9781000765151
Language: EN, FR, DE, ES & NL

Promising Drug Molecules of Natural Origin Book Review:

This new volume, Promising Drug Molecules of Natural Origin, explores potential beneficial drug substances derived from nature. It presents the general principles, characteristics, evaluation techniques, and applications involved in drug molecules from natural sources, such as plants and marine life. With chapters from renowned experts from around the world, the chapters in this volume address the challenges of standardization of herbal medicines, methods of characterization of natural medicines and phyto-constituents, and quality control methods for herbal medicines. Several chapters in the book focus on the evolution of phyto-constituents in cancer therapeutics, while others deal with applications for other diseases, such as diabetes and neuroinflammatory disorders. The volume also specifically reviews heterocyclic drugs from plants. This volume will be a valuable resource for faculty and advanced students in pharmaceutics as well as researchers, scientists, and industry professionals in medicine and drug development.

Encyclopedia of Chromatography Print

Encyclopedia of Chromatography  Print
Author: Jack Cazes
Publsiher: CRC Press
Total Pages: 927
Release: 2001-06-29
ISBN 10: 9780824705114
ISBN 13: 0824705114
Language: EN, FR, DE, ES & NL

Encyclopedia of Chromatography Print Book Review:

This practical, single-volume source collects up-to-date information on chromatographic techniques and methodologies for the solution of analytical and preparative problems applicable across a broad spectrum of disciplines including biotechnology, pharmaceuticals, environmental sciences, polymers, food additives and nutrients, pathology, toxicology, fossil fuels, and nuclear chemistry. It highlights real-world applications, easy-to-read fundamentals of problem solving and material identification methods, and detailed references. Written by over 180 esteemed international authorities and containing over 300 chapters, 2600 works cited, and 1000 drawings, equations, tables, and photographs, the Encyclopedia of Chromatography covers high-performance liquid, thin-layer, gas, affinity, countercurrent, supercritical fluid, gel permeation, and size exclusion chromatographies as well as capillary electrophoresis, field-flow fractionation, hyphenated techniques, and more. PRINT/ONLINE PRICING OPTIONS AVAILABLE UPON REQUEST AT [email protected]

Handbook of Pharmaceutical Analysis by HPLC

Handbook of Pharmaceutical Analysis by HPLC
Author: Satinder Ahuja,Michael Dong
Publsiher: Elsevier
Total Pages: 600
Release: 2005-02-09
ISBN 10: 9780080455181
ISBN 13: 0080455182
Language: EN, FR, DE, ES & NL

Handbook of Pharmaceutical Analysis by HPLC Book Review:

High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling

Separation Methods in Drug Synthesis and Purification

Separation Methods in Drug Synthesis and Purification
Author: Klara Valko
Publsiher: Elsevier
Total Pages: 788
Release: 2020-06-19
ISBN 10: 0444640711
ISBN 13: 9780444640710
Language: EN, FR, DE, ES & NL

Separation Methods in Drug Synthesis and Purification Book Review:

Separation Methods in Drug Synthesis and Purification, Second Edition, Volume Eight, provides an updated on the analytical techniques used in drug synthesis and purification. Unlike other books on either separation science or drug synthesis, this volume combines the two to explain the basic principles and comparisons of each separation technique. New sections to this volume include enantiomer separation using capillary electrophoresis (CE) and capillary electro- chromatography, the computer simulation of chromatographic separation for accelerating method development, the application of chromatography and capillary electrophoresis used as surrogates for biological processes, and new developments in the established techniques of chromatography and preparative methods. Features descriptions and applications of all separation methods used in the pharmaceutical industry Written by the leading scientists in their respective fields, providing solutions for a wide range of industrial separation problems encountered within the pharmaceutical industry Thoroughly updated with brand new separation science techniques and the latest developments in the established techniques of chromatography

HPLC Method Development for Pharmaceuticals

HPLC Method Development for Pharmaceuticals
Author: Satinder Ahuja,Henrik Rasmussen
Publsiher: Elsevier
Total Pages: 532
Release: 2011-09-21
ISBN 10: 0080554199
ISBN 13: 9780080554198
Language: EN, FR, DE, ES & NL

HPLC Method Development for Pharmaceuticals Book Review:

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

Modern HPLC for Practicing Scientists

Modern HPLC for Practicing Scientists
Author: Michael W. Dong
Publsiher: John Wiley & Sons
Total Pages: 304
Release: 2016-04-06
ISBN 10: 111929360X
ISBN 13: 9781119293606
Language: EN, FR, DE, ES & NL

Modern HPLC for Practicing Scientists Book Review:

A comprehesive yet concise guide to Modern HPLC Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers. Topics covered include: HPLC operation Method development Maintenance and troubleshooting Modern trends in HPLC such as quick-turnaround and "greener" methods Regulatory aspects While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources. With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.

Introduction to Pharmaceutical Chemical Analysis

Introduction to Pharmaceutical Chemical Analysis
Author: Steen Honoré Hansen,Stig Pedersen-Bjergaard,Knut Rasmussen
Publsiher: John Wiley & Sons
Total Pages: 624
Release: 2011-10-18
ISBN 10: 1119954339
ISBN 13: 9781119954330
Language: EN, FR, DE, ES & NL

Introduction to Pharmaceutical Chemical Analysis Book Review:

This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples

Mixed Mode Chromatography

Mixed Mode Chromatography
Author: Qian-Hong Wan
Publsiher: Springer Nature
Total Pages: 482
Release: 2021-11-23
ISBN 10: 9811654859
ISBN 13: 9789811654855
Language: EN, FR, DE, ES & NL

Mixed Mode Chromatography Book Review:

The book is about the technology and application of Mixed-mode chromatography (MMC). Unlike conventional single-mode HPLC, which resolves the analytes primarily based on their ionic or hydrophobic properties, MMC employs multifunctional stationary phases to exploit at least two modes of interactions (i.e., ionic and hydrophobic) with the analytes and as such often provides resolution that far exceeds that observed with a single-mode process. Over the past two decades, MMC has developed into an important analytical and purification tool in a number of applications in pharmaceutical and biotechnology industries. The technique has been used widely for the analyses of nucleic acids, amino acids, peptides, proteins, glycoproteins, carbohydrates, antibiotics, vaccines, and other products. The purpose of this book is to present a comprehensive survey of mixed-mode chromatography and is intended as a reference guide for graduate students and experienced scientists in pharmaceutical and biotechnology disciplines wishing to gain a deep understanding of this continuously evolving technology.

Thin Layer Chromatography in Drug Analysis

Thin Layer Chromatography in Drug Analysis
Author: Lukasz Komsta,Monika Waksmundzka-Hajnos,Joseph Sherma
Publsiher: CRC Press
Total Pages: 1067
Release: 2013-12-20
ISBN 10: 1466507160
ISBN 13: 9781466507166
Language: EN, FR, DE, ES & NL

Thin Layer Chromatography in Drug Analysis Book Review:

Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It requires less complicated or expensive equipment than other techniques, and has the ability to be performed under field conditions. Filling the need for an up-to-date

Mass Spectrometry in Drug Discovery

Mass Spectrometry in Drug Discovery
Author: David T. Rossi,Michael Sinz
Publsiher: CRC Press
Total Pages: 436
Release: 2001-11-07
ISBN 10: 9781420002478
ISBN 13: 1420002473
Language: EN, FR, DE, ES & NL

Mass Spectrometry in Drug Discovery Book Review:

Mass Spectrometry in Drug Discovery summarizes the theory, instrumentation, techniques, and application of mass spectrometry and atmospheric pressure ionization to screening, evaluating, and improving the performance and quality of drug candidates. It provides time- and cost-efficient approaches for the generation and analysis of effective pharmaceuticals, covers advances in combinatorial chemistry, molecular biology, bioanalysis automation, and computing, and demonstrates the use of mass spectrometry in the assessment of disease states, drug targets, and potential drug agents.

Identification and Quantification of Drugs Metabolites and Metabolizing Enzymes by LC MS

Identification and Quantification of Drugs  Metabolites and Metabolizing Enzymes by LC MS
Author: Swapan Chowdhury
Publsiher: Elsevier
Total Pages: 354
Release: 2005-11-04
ISBN 10: 9780080456065
ISBN 13: 0080456065
Language: EN, FR, DE, ES & NL

Identification and Quantification of Drugs Metabolites and Metabolizing Enzymes by LC MS Book Review:

As new techniques of transferring from liquid to gas phase and measuring masses of drug molecules and metabolites become more prevalent, so do the technical challenges of putting these techniques into proper use, as well as the task of consolidating emerging applications. Identification and Quantification of Drugs, Metabolites and Metabolizing Enzymes by LC-MS, Volume 6 fills the gap in the lack of presently available literature by providing a critical review in the current use of liquid chromatography-mass spectrometry (LC-MS) in drug discovery and development. With chapters written by experts with a wide range of practical experience from the pharmaceutical industry, emphasis is placed on techniques and applications. The book also includes chapters on how to utilize LC-MS instrumentation for current drug metabolism problems. This book is intended for those beginning to use LC-MS for drug metabolism studies as well as for those considered advanced practitioners. * Introduces readers to the practical applications of modern liquid chromatography-mass spectrometry (LC-MS) in a wide range of drug metabolism studies· * Provides a comprehensive description of different forms of metabolites, with detailed discussion on the wide range of methodologies used to identify them * Highlights problems associated with drug quantification and offers practical solutions

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography
Author: Steven H.Y. Wong
Publsiher: Routledge
Total Pages: 512
Release: 2017-09-19
ISBN 10: 135140847X
ISBN 13: 9781351408479
Language: EN, FR, DE, ES & NL

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography Book Review:

First Published in 2017. Routledge is an imprint of Taylor & Francis, an Informa company.

Liquid Chromatography

Liquid Chromatography
Author: G. Baird
Publsiher: Elsevier Inc. Chapters
Total Pages: 688
Release: 2013-01-08
ISBN 10: 0128071265
ISBN 13: 9780128071267
Language: EN, FR, DE, ES & NL

Liquid Chromatography Book Review:

Clinical chemistry is the discipline within laboratory medicine concerned with measuring the concentrations of analytes in blood, body fluids, and tissues. Liquid chromatography is already commonly used in the clinical chemistry laboratory for measuring the concentrations of small molecules, such as drugs and hormones, using a variety of solid phases for separation and numerous detection modalities, most important mass spectrometry. Additional liquid chromatographic methods are now being developed for measuring the concentrations of proteins in blood and tissues, taking advantage of the rapid development of novel mass-spectrometry instruments and methodologies.

Selectivity and Detectability Optimizations in HPLC

Selectivity and Detectability Optimizations in HPLC
Author: Satinder Ahuja
Publsiher: John Wiley & Sons
Total Pages: 624
Release: 1989-06-06
ISBN 10: 9780471626459
ISBN 13: 0471626457
Language: EN, FR, DE, ES & NL

Selectivity and Detectability Optimizations in HPLC Book Review:

High Performance Liquid Chromatography Edited by Phyllis Brown and Richard Hartwick This contributed volume is designed to consolidate the basic theories of chromatography along with the more exciting developments in the field. This monograph addresses some questions that concern researchers in separation science, including: what is the current state of the art in liquid chromatography; has the development of liquid chromatography plateaued; if so, what new methods will take its place or complement it; and if not, where will the new frontiers be and what direction will liquid chromatography take? 1989 (0 471-84506-X) 688 pp. Quantitative Structure-Chromatographic Retention Relationships R. Kaliszan Written by a pioneer in the field, this book extends and updates research on quantitative structure retention relationships by consolidating and critically reviewing the extensive literature on the subject, while also providing the basic theoretical and practical information required in all investigations involving chromatography, analytical chemistry, biochemistry, and pharmaceutical research. Among the topics covered are the nature of chromatographic interactions, molecular interpretation of distribution processes in chromatography, topological indices as retention descriptors, and multiparameter structure-chromatographic retention relationships. 1987 (0 471-85983-4) 303 pp. Detectors for Liquid Chromatography Edited by Edward S. Yeung With its singular coverage of this fast-growing field, Detectors for Liquid Chromatography presents the state of the art in this subject area. It offers a comprehensive examination of the basic principles behind the detector response, instrumentation, and selected applications for comparison and evaluation of potential. Specifically, topics given in-depth coverage include polarimetric, indirect absorbance, refractive index detectors, absorption detectors for HPLC, FTIR and fluorometric detection, detection based on electrical and electromechanical measurements, and mass spectroscopy as an on-line detector for HPLC. 1986 (0 471-82169-1) 366 pp.

Single Molecule Spectroscopy

Single Molecule Spectroscopy
Author: R. Rigler,M. Orrit,T. Basche
Publsiher: Springer Science & Business Media
Total Pages: 355
Release: 2012-12-06
ISBN 10: 3642565441
ISBN 13: 9783642565441
Language: EN, FR, DE, ES & NL

Single Molecule Spectroscopy Book Review:

The topics range from single molecule experiments in quantum optics and solid-state physics to analogous investigations in physical chemistry and biophysics.

Separation Methods in Drug Synthesis and Purification

Separation Methods in Drug Synthesis and Purification
Author: Klara Valko
Publsiher: Elsevier
Total Pages: 612
Release: 2000-10-13
ISBN 10: 9780080541099
ISBN 13: 0080541097
Language: EN, FR, DE, ES & NL

Separation Methods in Drug Synthesis and Purification Book Review:

Separation Methods in Drug Synthesis and Purification

Preparative Chromatography for Separation of Proteins

Preparative Chromatography for Separation of Proteins
Author: Arne Staby,Anurag S. Rathore,Satinder Ahuja
Publsiher: John Wiley & Sons
Total Pages: 608
Release: 2017-02-02
ISBN 10: 1119031176
ISBN 13: 9781119031178
Language: EN, FR, DE, ES & NL

Preparative Chromatography for Separation of Proteins Book Review:

Preparative Chromatography for Separation of Proteins addresses a wide range of modeling, techniques, strategies, and case studies of industrial separation of proteins and peptides. • Covers broad aspects of preparative chromatography with a unique combination of academic and industrial perspectives • Presents Combines modeling with compliantce useing of Quality-by-Design (QbD) approaches including modeling • Features a variety of chromatographic case studies not readily accessible to the general public • Represents an essential reference resource for academic, industrial, and pharmaceutical researchers