Biochemical Analysis Tools

Biochemical Analysis Tools
Author: Oana-Maria Boldura,Cornel Balta,Prof Nasser Awwad
Publsiher: BoD – Books on Demand
Total Pages: 206
Release: 2020-06-24
ISBN 10: 1789848563
ISBN 13: 9781789848564
Language: EN, FR, DE, ES & NL

Biochemical Analysis Tools Book Review:

This book explores the role of nucleic acid analysis and the advances it has led to in the field of life sciences. The first section is a collection of chapters covering experimental methods used in molecular biology, the techniques adjacent to these methods, and the steps of analysis before and after obtaining raw DNA data. The second section deals with the principles of chromatography, method development, sample preparation, and industrial applications.

Promising Drug Molecules of Natural Origin

Promising Drug Molecules of Natural Origin
Author: Rohit Dutt,Anil K. Sharma,Raj K. Keservani,Vandana Garg
Publsiher: CRC Press
Total Pages: 458
Release: 2020-11-04
ISBN 10: 1000765156
ISBN 13: 9781000765151
Language: EN, FR, DE, ES & NL

Promising Drug Molecules of Natural Origin Book Review:

This new volume, Promising Drug Molecules of Natural Origin, explores potential beneficial drug substances derived from nature. It presents the general principles, characteristics, evaluation techniques, and applications involved in drug molecules from natural sources, such as plants and marine life. With chapters from renowned experts from around the world, the chapters in this volume address the challenges of standardization of herbal medicines, methods of characterization of natural medicines and phyto-constituents, and quality control methods for herbal medicines. Several chapters in the book focus on the evolution of phyto-constituents in cancer therapeutics, while others deal with applications for other diseases, such as diabetes and neuroinflammatory disorders. The volume also specifically reviews heterocyclic drugs from plants. This volume will be a valuable resource for faculty and advanced students in pharmaceutics as well as researchers, scientists, and industry professionals in medicine and drug development.

Encyclopedia of Chromatography Print

Encyclopedia of Chromatography  Print
Author: Jack Cazes
Publsiher: CRC Press
Total Pages: 927
Release: 2001-06-29
ISBN 10: 9780824705114
ISBN 13: 0824705114
Language: EN, FR, DE, ES & NL

Encyclopedia of Chromatography Print Book Review:

This practical, single-volume source collects up-to-date information on chromatographic techniques and methodologies for the solution of analytical and preparative problems applicable across a broad spectrum of disciplines including biotechnology, pharmaceuticals, environmental sciences, polymers, food additives and nutrients, pathology, toxicology, fossil fuels, and nuclear chemistry. It highlights real-world applications, easy-to-read fundamentals of problem solving and material identification methods, and detailed references. Written by over 180 esteemed international authorities and containing over 300 chapters, 2600 works cited, and 1000 drawings, equations, tables, and photographs, the Encyclopedia of Chromatography covers high-performance liquid, thin-layer, gas, affinity, countercurrent, supercritical fluid, gel permeation, and size exclusion chromatographies as well as capillary electrophoresis, field-flow fractionation, hyphenated techniques, and more. PRINT/ONLINE PRICING OPTIONS AVAILABLE UPON REQUEST AT [email protected]

Handbook of Pharmaceutical Analysis

Handbook of Pharmaceutical Analysis
Author: Lena Ohannesian,Anthony Streeter
Publsiher: CRC Press
Total Pages: 608
Release: 2001-11-09
ISBN 10: 0824741943
ISBN 13: 9780824741945
Language: EN, FR, DE, ES & NL

Handbook of Pharmaceutical Analysis Book Review:

Exploring the analysis of pharmaceuticals, including polymorphic forms, this book discusses regulatory requirements in pharmaceutical product development and pharmaceutical testing. It covers methods of drug separation and procedures such as capillary electrophoresis for chromatographic separation of molecules. Additional topics include drug formulation analysis using vibrational and magnetic resonance spectroscopy and identification of drug metabolites and decomposition products using such techniques as mass spectrometry. The book provides more than 300 tables, equations, drawings, and photographs, and convenient, easy-to-use indices, facilitating quick access to each topic.

Handbook of Pharmaceutical Analysis by HPLC

Handbook of Pharmaceutical Analysis by HPLC
Author: Satinder Ahuja,Michael Dong
Publsiher: Elsevier
Total Pages: 600
Release: 2005-02-09
ISBN 10: 9780080455181
ISBN 13: 0080455182
Language: EN, FR, DE, ES & NL

Handbook of Pharmaceutical Analysis by HPLC Book Review:

High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling

Introduction to Pharmaceutical Chemical Analysis

Introduction to Pharmaceutical Chemical Analysis
Author: Steen Honoré Hansen,Stig Pedersen-Bjergaard,Knut Rasmussen
Publsiher: John Wiley & Sons
Total Pages: 624
Release: 2011-10-18
ISBN 10: 1119954339
ISBN 13: 9781119954330
Language: EN, FR, DE, ES & NL

Introduction to Pharmaceutical Chemical Analysis Book Review:

This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the pharmacy student, to teach the requirements in “analytical chemistry” for the 5 years pharmacy curriculum, but the textbook is also intended for analytical chemists moving into the field of pharmaceutical analysis. Addresses the basic concepts, then establishes the foundations for the common analytical methods that are currently used in the quantitative and qualitative chemical analysis of pharmaceutical drugs Provides an understanding of common analytical techniques used in all areas of pharmaceutical development Suitable for a foundation course in chemical and pharmaceutical sciences Aimed at undergraduate students of degrees in Pharmaceutical Science/Chemistry Analytical Science/Chemistry, Forensic analysis Includes many illustrative examples

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography
Author: Steven H.Y. Wong
Publsiher: Routledge
Total Pages: 512
Release: 2017-09-19
ISBN 10: 1351408461
ISBN 13: 9781351408462
Language: EN, FR, DE, ES & NL

Therapeutic Drug Monitoring and Toxicology by Liquid Chromatography Book Review:

First Published in 2017. Routledge is an imprint of Taylor & Francis, an Informa company.

HPLC for Pharmaceutical Scientists

HPLC for Pharmaceutical Scientists
Author: Yuri V. Kazakevich,Rosario LoBrutto
Publsiher: John Wiley & Sons
Total Pages: 1080
Release: 2007-02-16
ISBN 10: 0470087943
ISBN 13: 9780470087947
Language: EN, FR, DE, ES & NL

HPLC for Pharmaceutical Scientists Book Review:

HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.

Thin Layer Chromatography in Drug Analysis

Thin Layer Chromatography in Drug Analysis
Author: Lukasz Komsta,Monika Waksmundzka-Hajnos,Joseph Sherma
Publsiher: CRC Press
Total Pages: 1067
Release: 2013-12-20
ISBN 10: 1466507160
ISBN 13: 9781466507166
Language: EN, FR, DE, ES & NL

Thin Layer Chromatography in Drug Analysis Book Review:

Used routinely in drug control laboratories, forensic laboratories, and as a research tool, thin layer chromatography (TLC) plays an important role in pharmaceutical drug analyses. It requires less complicated or expensive equipment than other techniques, and has the ability to be performed under field conditions. Filling the need for an up-to-date

Preparative Chromatography for Separation of Proteins

Preparative Chromatography for Separation of Proteins
Author: Arne Staby,Anurag S. Rathore,Satinder Ahuja
Publsiher: John Wiley & Sons
Total Pages: 608
Release: 2017-02-02
ISBN 10: 1119031176
ISBN 13: 9781119031178
Language: EN, FR, DE, ES & NL

Preparative Chromatography for Separation of Proteins Book Review:

Preparative Chromatography for Separation of Proteins addresses a wide range of modeling, techniques, strategies, and case studies of industrial separation of proteins and peptides. • Covers broad aspects of preparative chromatography with a unique combination of academic and industrial perspectives • Presents Combines modeling with compliantce useing of Quality-by-Design (QbD) approaches including modeling • Features a variety of chromatographic case studies not readily accessible to the general public • Represents an essential reference resource for academic, industrial, and pharmaceutical researchers

Preparative Chromatography for Separation of Proteins

Preparative Chromatography for Separation of Proteins
Author: Arne Staby,Anurag S. Rathore,Satinder Ahuja
Publsiher: John Wiley & Sons
Total Pages: 608
Release: 2017-03-06
ISBN 10: 1119031109
ISBN 13: 9781119031109
Language: EN, FR, DE, ES & NL

Preparative Chromatography for Separation of Proteins Book Review:

"Preparative Chromatography for Separation of Proteins addresses a wide range of the most current modeling techniques, strategies, and case studies of industrial separation of proteins and peptides to aid in the efficiency and efficacy of this broadly-used technique in the purification of biopharmaceuticals"--

Integrated Strategies for Drug Discovery Using Mass Spectrometry

Integrated Strategies for Drug Discovery Using Mass Spectrometry
Author: Mike S. Lee
Publsiher: John Wiley & Sons
Total Pages: 576
Release: 2005-09-02
ISBN 10: 0471721026
ISBN 13: 9780471721024
Language: EN, FR, DE, ES & NL

Integrated Strategies for Drug Discovery Using Mass Spectrometry Book Review:

New strategies and techniques for today's fast-paced discoveryprocess Today, the pressure is on for high-throughput approaches toaccelerate the generation, identification, and optimization ofmolecules with desirable drug properties. As traditional methods ofanalysis become antiquated, new analytical strategies andtechniques are necessary to meet sample throughput requirements andmanpower constraints. Among them, mass spectrometry has grown to bea front-line tool throughout drug discovery. Integrated Strategies for Drug Discovery Using Mass Spectrometryprovides a thorough review of current analytical approaches,industry practices, and strategies in drug discovery. The topicsrepresent current industry benchmarks in specific drug discoveryactivities that deal with proteomics, biomarker discovery,metabonomic approaches for toxicity screening, lead identification,compound libraries, quantitative bioanalytical support,biotransformation, reactive metabolite characterization, leadoptimization, pharmaceutical property profiling, sample preparationstrategies, and automation. THIS BOOK: * Clearly explains how drug discovery and mass spectrometry areinterconnected * Discusses the uses and limitations of various types of massspectrometry in various aspects of drug discovery * Prominently features analytical applications that requiretrace-mixture analysis * Provides industry applications and real-world examples * Shares historical background information on various techniques toaid in the understanding of how and why new methods are now beingemployed to analyze samples

Multi Objective Optimization in Chemical Engineering

Multi Objective Optimization in Chemical Engineering
Author: Gade Pandu Rangaiah,Adri¿n Bonilla-Petriciolet
Publsiher: John Wiley & Sons
Total Pages: 528
Release: 2013-03-20
ISBN 10: 1118341686
ISBN 13: 9781118341681
Language: EN, FR, DE, ES & NL

Multi Objective Optimization in Chemical Engineering Book Review:

For reasons both financial and environmental, there is a perpetual need to optimize the design and operating conditions of industrial process systems in order to improve their performance, energy efficiency, profitability, safety and reliability. However, with most chemical engineering application problems having many variables with complex inter-relationships, meeting these optimization objectives can be challenging. This is where Multi-Objective Optimization (MOO) is useful to find the optimal trade-offs among two or more conflicting objectives. This book provides an overview of the recent developments and applications of MOO for modeling, design and operation of chemical, petrochemical, pharmaceutical, energy and related processes. It then covers important theoretical and computational developments as well as specific applications such as metabolic reaction networks, chromatographic systems, CO2 emissions targeting for petroleum refining units, ecodesign of chemical processes, ethanol purification and cumene process design. Multi-Objective Optimization in Chemical Engineering: Developments and Applications is an invaluable resource for researchers and graduate students in chemical engineering as well as industrial practitioners and engineers involved in process design, modeling and optimization.

Molecular Biology in Medicinal Chemistry

Molecular Biology in Medicinal Chemistry
Author: Theodor Dingermann,Dieter Steinhilber,Gerd Folkers
Publsiher: John Wiley & Sons
Total Pages: 435
Release: 2006-03-06
ISBN 10: 3527605185
ISBN 13: 9783527605187
Language: EN, FR, DE, ES & NL

Molecular Biology in Medicinal Chemistry Book Review:

This readily comprehensible book explains the identification of molecular targets via cellular assays, reporter genes or transgenic models, as well as surveying recent advances in the synthesis, separation and analysis of drugs. A special section is devoted to molecular genetics methods. With its examination of these novel methods and generous practical advice, this is essential reading for all pharmaceutical chemists, molecular biologists and medical researchers using molecular methods to study drugs and their action.

Chromatographic Techniques in the Forensic Analysis of Designer Drugs

Chromatographic Techniques in the Forensic Analysis of Designer Drugs
Author: Teresa Kowalska,Mieczyslaw Sajewicz,Joseph Sherma
Publsiher: CRC Press
Total Pages: 478
Release: 2018-01-31
ISBN 10: 1315313154
ISBN 13: 9781315313153
Language: EN, FR, DE, ES & NL

Chromatographic Techniques in the Forensic Analysis of Designer Drugs Book Review:

There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials. The methods are based on molecular characteristics of the drugs belonging to each individual class of compounds, so it will be clear how the current methods are adaptable to future new drugs that appear in the market.

Pharmaceutical and Biomedical Applications of Liquid Chromatography

Pharmaceutical and Biomedical Applications of Liquid Chromatography
Author: W.J. Lough,I.W. Wainer,Christopher M. Riley
Publsiher: Newnes
Total Pages: 393
Release: 2013-10-22
ISBN 10: 0080984541
ISBN 13: 9780080984544
Language: EN, FR, DE, ES & NL

Pharmaceutical and Biomedical Applications of Liquid Chromatography Book Review:

This volume reflects the changes that have taken place in the pharmaceutical industry over the last ten years, most notably the increased importance attached to the question of chirality, the growing influence of biotechnology and the need for more rigorous documentation and validation of analytical methods and procedures. The first part of this book deals with the application of new technology to pharmaceutical and biomedical analysis, reflecting the present needs for increased speed, sensitivity and selectivity in the analysis of drugs. The second chapter provides an overview of capillary electophoresis, which represents one of the most inportant analytical developments to impact directly on pharmaceutical development in recent years. Although not a chromatographic technique, capillary electrophoresis was considered too important to be ignored. Over the last 25 years, liquid chromatography has grown into a mature analytical technique and many of the fundamental issues concerned with retention and separation are well defined. The practitioners of modern liquid chromatography spend as much time in the development of techniques for sampling handling and automation as they do in the development of the separation. Therefore, Part Two of this book describes some of the recent advances in the areas of sample handling and the isolation of compounds from biological samples, including solid phase extraction, restricted access media for direct injection, coupled column technology and microdialysis. Similarily, Part Three contains two chapters concerned with liquid chromatographic methods for the isolation of drug substances, peptides and proteins from other complex media. The pharmaceutical industry and the process of drug development are highly regulated and the increasing importance that the regulatory authorities attach to validation has had a significant impact on the analytical techniques used for the analysis of drugs. Although this has increased the workload of analysts in the pharmaceutical industry, it has also improved the quality of analytical methods used in the support of investigational and new drug applications as well as the quality of methods published more recently in the literature. Consequently, Part Four of this volume describes approaches to the optimization and validation of liquid chromatography methods for the analysis of drugs in the bulk form, in pharmaceutical formulations and biological fluids.

Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations HPLC And HPTLC Techniques

Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations  HPLC And HPTLC Techniques
Author: Satish Y. Gabhe
Publsiher: diplom.de
Total Pages: 108
Release: 2015-08-01
ISBN 10: 3954898071
ISBN 13: 9783954898077
Language: EN, FR, DE, ES & NL

Development And Validation Of Chromatographic Methods For Simultaneous Quantification Of Drugs In Bulk And In Their Formulations HPLC And HPTLC Techniques Book Review:

This book details: 1. Development and validation of a HPTLC-densitometric method for concurrent estimation of metformin hydrochloride, pioglitazone hydrochloride and gliclazide in combined dosage form. 2. Development and validation of a HPTLC method for simultaneous estimation of moxifloxacin hydrochloride and dexamethasone sodium phosphate in combined pharmaceutical dosage form. 3. Development and validation of a RP-HPLC method for simultaneous estimation of ciprofloxacin hydrochloride and dexamethasone in combined dosage form, which is a better alternative to existing ones. The developed analytical methods are simple, selective, accurate, robust, and precise with shorter analysis time for the analysis of drug/s in combined pharmaceutical dosage forms. All the developed HPTLC and HPLC methods have been validated as per ICH Q2 (R1) guideline. Developed analytical methods could boost analytical researchers to work more efficiently in the field of analytical method development and validation of Pharmaceutical dosage forms.

Liquid Chromatography

Liquid Chromatography
Author: Salvatore Fanali,Paul R. Haddad,Colin Poole,Marja-Liisa Riekkola
Publsiher: Elsevier
Total Pages: 808
Release: 2017-06-22
ISBN 10: 0128093455
ISBN 13: 9780128093450
Language: EN, FR, DE, ES & NL

Liquid Chromatography Book Review:

Liquid Chromatography: Fundamentals and Instrumentation, Second Edition, is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their understanding of new fundamentals and instrumentation techniques in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Supercritical Fluid Chromatography

Supercritical Fluid Chromatography
Author: Gregory K. Webster
Publsiher: CRC Press
Total Pages: 418
Release: 2014-02-04
ISBN 10: 9814463000
ISBN 13: 9789814463003
Language: EN, FR, DE, ES & NL

Supercritical Fluid Chromatography Book Review:

Analytical chemists in the pharmaceutical industry are always looking for more-efficient techniques to meet the analytical challenges of today’s pharmaceutical industry. One technique that has made steady advances in pharmaceutical analysis is supercritical fluid chromatography (SFC). SFC is meeting the chromatography needs of the industry by providing efficient and selective testing capabilities on the analytical and preparative scale. The supercritical fluid mobile phase, consisting mainly of CO2, facilitates cost reduction costs and helps the industry in meeting green chemistry standards. This book provides a comprehensive overview of the use of SFC in pharmaceutical analysis. Supercritical Fluid Chromatography reviews the use of SFC in drug-discovery applications and describes its application in drug development. When a drug is developed and brought to market, it is tested many times for impurities and degradants, enantiomeric purity, and analytical and preparative isolations—it is tested during discovery and development and for under-regulated and unregulated methodologies. The book describes the use of SFC for each of these applications and discusses more in-depth topics, such as the use of SFC in mass spectrometric and polarographic detection. The book also sheds light on the role of SFC in drug development from natural products and the advancement of SFC with new technologies and its use in pilot-scale operations as a chromatographic technique.

Preparative Liquid Chromatography

Preparative Liquid Chromatography
Author: B.A. Bidlingmeyer
Publsiher: Elsevier
Total Pages: 340
Release: 1987-07-01
ISBN 10: 9780080858418
ISBN 13: 0080858414
Language: EN, FR, DE, ES & NL

Preparative Liquid Chromatography Book Review:

This volume provides a straightforward approach to isolation and purification problems with a thorough presentation of preparative LC strategy including the interrelationship between the input and output of the instrumentation, while keeping to an application focus. The book stresses the practical aspects of preparative scale separations from TLC isolations through various laboratory scale column separations to very large scale production. It also gives a thorough description of the performance parameters (e.g. throughput, separation quality, etc.) as a function of operational parameters (e.g. particle size, column size, solvent usage, etc.). Experts in the field have contributed a well balanced presentation of separation development strategies from preparative TLC to commercial preparative process with practical examples in a wide variety of application areas such as drugs, proteins, nucleotides, industrial extracts, organic chemicals, enantiomers, polymers, etc.