Cancer Stem Cells

Cancer Stem Cells
Author: Huiping Liu,Justin Durla Lathia
Publsiher: Elsevier
Total Pages: 542
Release: 2016-08-16
ISBN 10: 0128039345
ISBN 13: 9780128039342
Language: EN, FR, DE, ES & NL

Cancer Stem Cells Book Review:

Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance introduces the basic concepts and advanced understanding of cancer stem cells, covering general overviews, organ-specific identifications, and their characteristic mechanisms. The book also explores innovative therapeutic strategies in preclinical and clinical trials to target cancer stem cells, remove the roots of cancer, eliminate the seeds of metastasis, overcome the resistance of therapies, and contribute to the eradication of cancer. The book includes contributions from leading, worldwide experts in the field, helping readers embrace new hope in their quest to eradicate cancer with emerging clinical trials on treating cancer stem cells in combination with other therapies. Provides an authoritative and complete overview of cancer stem cells Includes comprehensive coverage of current therapeutic strategies targeting cancer stem cells Deepens a reader’s technical expertise in cancer stem cell biology

Cancer Stem Cells

Cancer Stem Cells
Author: Lucie Laplane
Publsiher: Harvard University Press
Total Pages: 252
Release: 2016-06-06
ISBN 10: 0674088743
ISBN 13: 9780674088740
Language: EN, FR, DE, ES & NL

Cancer Stem Cells Book Review:

A new therapeutic strategy could break the stalemate in the war on cancer by targeting not all cancerous cells but the small fraction that lie at the root of cancers. Lucie Laplane offers a comprehensive analysis of cancer stem cell theory, based on an original interdisciplinary approach that combines biology, biomedical history, and philosophy.

Cancer Stem Cells

Cancer Stem Cells
Author: Vinagolu K. Rajasekhar
Publsiher: John Wiley & Sons
Total Pages: 552
Release: 2014-01-27
ISBN 10: 1118356179
ISBN 13: 9781118356173
Language: EN, FR, DE, ES & NL

Cancer Stem Cells Book Review:

Cancer Stem Cells covers a wide range of topics incancer stem cell biology, including the functional characteristicsof cancer stem cells and how they're generated, where they arelocalized, the means by which cancer stem cells can be targeted,and how cancer stem cells can be reprogrammed back to normal tissuestem cells. Each chapter begins with a brief historical note andconcept summary, followed by a description of the latest basic orclinical advance associated with the topic. Cancer Stem Cells builds systematically fromcoverage of the basic research stage to an advanced research level,from clinical relevance to therapeutic potential, and will be avaluable resource for professionals in the fields of cancerresearch and stem cell biology.

Cancer Stem Cells New Horizons in Cancer Therapies

Cancer Stem Cells  New Horizons in Cancer Therapies
Author: Surajit Pathak,Antara Banerjee
Publsiher: Springer Nature
Total Pages: 369
Release: 2020-10-17
ISBN 10: 9811551200
ISBN 13: 9789811551208
Language: EN, FR, DE, ES & NL

Cancer Stem Cells New Horizons in Cancer Therapies Book Review:

This book discusses the recent developments in the therapeutic implications of cancer stem cells for the effective diagnosis, prognosis, and treatment of cancer. It summarizes the various stem cells of common cancers including colon, pancreas, lungs, prostate, melanoma, and glioblastoma, and reviews the potential role of cancer stem cells in tissue aggressiveness, examining the functional contribution of cancer stem cells in the establishment and recurrence of cancerous tumors. Further, it explores the potential of cancer stem cells as novel therapeutic targets for the treatment and prevention of tumor progression. The book also discusses the various approaches for detecting, isolating, and characterizing different cancer stem cells and signaling pathways that control their replication, survival, and differentiation. Lastly, it explores the key features and mechanisms of drug resistance, chemo-resistance, and radio-resistance in cancer stem cells to improve therapeutic rationale.

The Cancer Stem Cell Niche

The Cancer Stem Cell Niche
Author: Susie Prof. Nilsson
Publsiher: Academic Press
Total Pages: 246
Release: 2021-01-23
ISBN 10: 0323853269
ISBN 13: 9780323853262
Language: EN, FR, DE, ES & NL

The Cancer Stem Cell Niche Book Review:

The Cancer Stem Cell Niche, Volume Five in the Advances in Stem Cells and their Niches series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Acute lymphoblastic leukemia and the bone marrow microenvironment, Stem cell niches in bone and their roles in cancer metastasis, The role of vasculature in cancer stem cell niches, The lung cancer stem cell niche, The prostate cancer stem cell niche: Genetic drivers and therapeutic approaches, Impact of prostate cancer stem cell niches on prostate cancer tumorigenesis and progression, The testicular cancer stem cell niche. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Advances in Stem Cells and their Niches series Includes the latest information on the Cancer Stem Cell Niche

The Heterogeneity of Cancer Metabolism

The Heterogeneity of Cancer Metabolism
Author: Anne Le
Publsiher: Springer
Total Pages: 183
Release: 2018-06-26
ISBN 10: 331977736X
ISBN 13: 9783319777368
Language: EN, FR, DE, ES & NL

The Heterogeneity of Cancer Metabolism Book Review:

Genetic alterations in cancer, in addition to being the fundamental drivers of tumorigenesis, can give rise to a variety of metabolic adaptations that allow cancer cells to survive and proliferate in diverse tumor microenvironments. This metabolic flexibility is different from normal cellular metabolic processes and leads to heterogeneity in cancer metabolism within the same cancer type or even within the same tumor. In this book, we delve into the complexity and diversity of cancer metabolism, and highlight how understanding the heterogeneity of cancer metabolism is fundamental to the development of effective metabolism-based therapeutic strategies. Deciphering how cancer cells utilize various nutrient resources will enable clinicians and researchers to pair specific chemotherapeutic agents with patients who are most likely to respond with positive outcomes, allowing for more cost-effective and personalized cancer therapeutic strategies.

Principles of Stem Cell Biology and Cancer

Principles of Stem Cell Biology and Cancer
Author: Tarik Regad,Thomas Sayers,Robert Rees
Publsiher: John Wiley & Sons
Total Pages: 376
Release: 2015-05-06
ISBN 10: 1118670620
ISBN 13: 9781118670620
Language: EN, FR, DE, ES & NL

Principles of Stem Cell Biology and Cancer Book Review:

Principles of Stem Cell Biology and Cancer: Future Applications and Therapeutics Tarik Regad, The John van Geest Cancer Research Centre, Nottingham Trent University, UK, Thomas J. Sayers, Centre for Cancer Research, National Cancer Institute, Frederick, USA and Robert Rees The John van Geest Cancer Research Centre, Nottingham Trent University, UK The field of cancer stem cells is expanding rapidly, with many groups focusing on isolating and identifying cancer stem cell populations. Although some progress has been made developing efficient cancer therapies, targeting cancer stem cells remains one of the important challenges facing the growing stem cell research community. Principles of Stem Cell Biology and Cancer brings together original contributions from international experts in the field to present the very latest information linking stem cell biology and cancer. Divided into two parts, the book begins with a detailed introduction to stem cell biology with a focus on the characterization of these cells, progress that has been made in their identification, as well as future therapeutic applications of stem cells. The second part focuses on cancer stem cells and their role in cancer development, progression and chemo-resistance. This section of the book includes an overview of recent progress concerning therapies targeting cancer stem cells. Features: An authoritative introduction to the link between stem cell biology and cancer. Includes contributions from leading international experts in the field. Well-illustrated with full colour figures throughout. This book will prove an invaluable resource for basic and applied researchers and clinicians working on the development of new cancer treatments and therapies, providing a timely publication of high quality reviews outlining the current progress and exciting future possibilities for stem cell research.

Stem Cells and Cancer in Hepatology

Stem Cells and Cancer in Hepatology
Author: Yun-Wen Zheng
Publsiher: Academic Press
Total Pages: 382
Release: 2018-05-18
ISBN 10: 0128123028
ISBN 13: 9780128123027
Language: EN, FR, DE, ES & NL

Stem Cells and Cancer in Hepatology Book Review:

Stem Cells and Cancer in Hepatology: From the Essentials to Application offers basic scientists and clinicians in the fields of stem cells, hepatology and oncology an overview of the interaction between liver biology, stem cells and cancer. It discusses how the liver performs regeneration and repair, the role stem cells play in these processes, and the mechanisms by which liver cancers are initiated and developed. As the field of stem cells and cancer stem cells in hepatology is new and dynamic, thus making it difficult for researchers and clinicians to understand the most relevant historic and novel studies, this volume addresses that challenge. Addresses both the basic and clinical perspectives of the topic, including sections on normal and cancer stem cells of the liver Provides coverage of the molecular mechanisms of liver development, the proliferation of hepatic progenitor cells during development, epithelial cell plasticity, generation of hepatocytes by transdifferentiation, liver tissue engineering, and more Presents a study of hepatic stem cells that will help readers understand critical events during development, stem cell differentiation towards functional liver cell fate, and tumor initiation

Therapeutic Targeting of Cancer Stem Like Cells CSC The Current State of the Art

Therapeutic Targeting of Cancer Stem Like Cells  CSC      The Current State of the Art
Author: Cyril Corbet,Alexandre Prieur
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-04-03
ISBN 10: 288963647X
ISBN 13: 9782889636471
Language: EN, FR, DE, ES & NL

Therapeutic Targeting of Cancer Stem Like Cells CSC The Current State of the Art Book Review:

Cancer Stem Cells

Cancer Stem Cells
Author: Sharmila A. Bapat
Publsiher: John Wiley & Sons
Total Pages: 276
Release: 2008-10-03
ISBN 10: 0470391561
ISBN 13: 9780470391563
Language: EN, FR, DE, ES & NL

Cancer Stem Cells Book Review:

Because the concept and discoveries of cancer stem cells are relatively new, scientists and researchers need an introduction to this dynamic area. Cancer Stem Cells presents a consolidated account of the research done to date and recent progresses in the studies of cancer stem cells. Such a presentation facilitates a better understanding of and draws attention to stem cell and cancer biology - two fields that enhance, move, and evolve into each other continuously. It provides an informative study in designing approaches to apply stem cell principles to cancer biology while offering an overview of the challenges in developing combination stem and cancer biology targets for therapeutics. This book serves as a primer for new researchers in the field of cancer biology.

Cancer Stem Cells

Cancer Stem Cells
Author: William L. Farrar
Publsiher: Cambridge University Press
Total Pages: 171
Release: 2010
ISBN 10: 0521896282
ISBN 13: 9780521896283
Language: EN, FR, DE, ES & NL

Cancer Stem Cells Book Review:

Explores the emerging field of research in cancer stem cells; covers the basic biology, genetic pathways and therapeutic targeting.

Stem Cells and Cancer Stem Cells Volume 4

Stem Cells and Cancer Stem Cells  Volume 4
Author: M.A. Hayat
Publsiher: Springer Science & Business Media
Total Pages: 319
Release: 2012-02-07
ISBN 10: 940072828X
ISBN 13: 9789400728288
Language: EN, FR, DE, ES & NL

Stem Cells and Cancer Stem Cells Volume 4 Book Review:

Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: embryonic stem cells, induced pluripotent stem cells, human hair follicle stem cells, bone marrow-derived human mesenchymal stem cells, adipose-derived stem cells, periodontal/progenitor cells, cancer stem cells, and breast cancer stem cells. Because human embryonic stem cells possess the potential to produce unlimited quantities of any human cell type, considerable focus is placed on this type of stem cells in this volume. The role of cancer stem cells, specifically in breast cancer is explained. Transplantation of mesenchymal stem cells to aid the injured brain is included. Immune recovery after stem cells transplantation in severe combined immunodeficiency patients is described. The role of mesenchymal stem cells in enhancing the growth and metastasis of colon cancer is discussed. Clinical application of human follicle stem cells is presented. Treatment of malignant gliomas using genetically-modified neural stem cells as a marker is discussed. The impact of cancer stem cell hypothesis on designing new cancer therapies is explained. In the field of regenerative medicine, the use of stem cells in the repair of the central nervous system, tendon injury, and as a cardiac regenerative medicine is described. The role of DNA methylation in maintaining stemness induced pluripotent stem cells from human extraembryonic amnion cells is discussed. Insights on the understanding of molecular pathways involved in tumor biology are explained, which lead to the development of effective drugs. Information on pathways, such as hedgehog, facilitates targeted therapies in cancer.

Mesenchymal Stem Cells in Cancer Therapy

Mesenchymal Stem Cells in Cancer Therapy
Author: Khalid Shah
Publsiher: Elsevier
Total Pages: 42
Release: 2013-12-18
ISBN 10: 0124166652
ISBN 13: 9780124166653
Language: EN, FR, DE, ES & NL

Mesenchymal Stem Cells in Cancer Therapy Book Review:

With the thorough understanding of stem cell biology and the advent of targeted therapeutics for cancer, stem cell-based therapeutic strategies are being increasingly explored for the treatment of various cancer types. Mesenchymal Stem Cells in Cancer Therapy sheds light on current stem cell based targeted therapies for cancer, by focusing on the application of mesenchymal stem cells (MSC) in various cancers with emphasis on a number of aspects that are critical to the success of future stem cell based therapies for cancer. Sections of this publication are devoted to developing stem cell based therapies for cancer with the main focus on tumoritrophic properties of stem cells, engineering targeted therapeutics, utilization of imaging techniques and the recent combination studies utilizing currently employed therapeutics with stem cells. Mesenchymal Stem Cells in Cancer Therapy informs readers about critical and cutting edge stem cell therapies for cancer and also enables them to appreciate the vast plain of unresolved questions in stem cell research for cancer therapeutics. Includes biological foundation on key sources of mesenchymal stem cells and the various ways they can be utilized to treat cancer. Provides examples of current MSC based cancer therapies and prospects for the future with insights from the leading lab on cancer cell therapies. Technically advanced topic written for widespread understanding for clinical and research audiences.

Stem Cells From Hype to Real Hope

Stem Cells     From Hype to Real Hope
Author: Khawaja Husnain Haider,Salim Aziz, MD
Publsiher: Walter de Gruyter GmbH & Co KG
Total Pages: 220
Release: 2018-12-17
ISBN 10: 3110586916
ISBN 13: 9783110586916
Language: EN, FR, DE, ES & NL

Stem Cells From Hype to Real Hope Book Review:

This book is a compilation of the bench experience of leading experts from various research labs involved in the cutting edge area of research. The authors describe the use of stem cells both as part of the combinatorial therapeutic intervention approach and as tools (disease model) during drug development, highlighting the shift from a conventional symptomatic treatment strategy to addressing the root cause of the disease process. The book is a continuum of the previously published book entitled "Stem Cells: from Drug to Drug Discovery" which was published in 2017.

Stem Cells for Cancer and Genetic Disease Treatment

Stem Cells for Cancer and Genetic Disease Treatment
Author: Phuc Van Pham,Ahmed El-Hashash
Publsiher: Springer
Total Pages: 190
Release: 2018-11-07
ISBN 10: 3319980653
ISBN 13: 9783319980652
Language: EN, FR, DE, ES & NL

Stem Cells for Cancer and Genetic Disease Treatment Book Review:

This invaluable resource discusses insights ranging from basic biological mechanisms of various types of stem cells through the potential applications in the treatment of human diseases, including cancer and genetic disorders. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in understanding different types of stem cell biology and their potential applications in tissue repair and regeneration and in the treatment different types of human cancer and genetic diseases or disorders. Stem Cells for Cancer and Genetic Disease Treatment and the other books in the Stem Cells in Clinical Applicationsseries will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering as well as cancer or genetics research.

Advances in Cancer Stem Cell Biology

Advances in Cancer Stem Cell Biology
Author: Roberto Scatena,Alvaro Mordente,Bruno Giardina
Publsiher: Springer Science & Business Media
Total Pages: 343
Release: 2011-10-06
ISBN 10: 9781461408093
ISBN 13: 1461408091
Language: EN, FR, DE, ES & NL

Advances in Cancer Stem Cell Biology Book Review:

In recent years, cancer stem cells have been recognized as important component in carcinogenesis and they seem to form the basis of many (if not all) tumor types. Cancer stem cells or "cancer cell like stem cells" have been isolated from various cancers of different origin (blood, breast, brain, skin, head and neck, thyroid, cervix, lung, retina, colon, pancreas and so on). Cancer stem cells - rare cells with indefinite proliferative potential that drive the formation and growth of tumours- seem to show intriguing relationships with physiological stem cells. Specifically, these cancer cells show significant similarities in the mechanisms that regulate self-renewal of normal stem cells. Moreover, tumour cells might directly arise from normal stem cells. Further, the cellular biology of cancer stem cells show a lot of similarities with normal stem cells.

Role of Cancer Stem Cells in Cancer Biology and Therapy

Role of Cancer Stem Cells in Cancer Biology and Therapy
Author: Thomas Dittmar,Kurt S. Zänker
Publsiher: CRC Press
Total Pages: 332
Release: 2016-04-19
ISBN 10: 1466577363
ISBN 13: 9781466577367
Language: EN, FR, DE, ES & NL

Role of Cancer Stem Cells in Cancer Biology and Therapy Book Review:

This book summarizes the latest findings about the role of cancer stem cells (CSCs) in cancer biology and how this knowledge could be used for novel anticancer therapies. It provides an overview of CSCs in selected malignancies with particular emphasis on hematopoietic neoplasias. It then reviews the role of CSCs in metastasis formation and initiation of cancer relapses. It also examines the dark side of cancer therapy such as conventional cancer therapies that may lead to the origin of recurrence CSCs. Finally, it supplies a brief overview of current concepts that may allow for a selective eradication of CSCs.

Prominin 1 CD133 New Insights on Stem Cancer Stem Cell Biology

Prominin 1  CD133   New Insights on Stem   Cancer Stem Cell Biology
Author: Denis Corbeil
Publsiher: Springer Science & Business Media
Total Pages: 252
Release: 2012-11-19
ISBN 10: 1461458943
ISBN 13: 9781461458944
Language: EN, FR, DE, ES & NL

Prominin 1 CD133 New Insights on Stem Cancer Stem Cell Biology Book Review:

​​​​​​​Prominin-1 or otherwise known as CD133 is a glycoprotein that is present in humans and mice. Since the first description of prominin in 1997, in mouse neuroepithelial cells and in human hematopoietic stem cells as AC133 antigen, this molecule has aroused a large interest especially, as a stem cell marker, that gave rise to an ever growing body of publications and more recently its expression in cancer stem cells. Controversies as to its role as a cancer stem and its detection in different models, as well as its use as a prognostic marker have emerged. Yet, beyond its use as a stem cell and cancer stem cell marker, prominin-1/CD133 displays unique biological features and appears of importance in other processes like for example in retinal biogenesis. Indeed, this five-transmembrane plasma membrane glycoprotein, which marks membrane protrusions is associated with several essential processes like cell polarity, asymmetric cell division and membrane remodeling. We propose to review current knowledge about this intriguing molecule and present pertinent information to determine the biological role of prominins and assess their importance in medicine and cancer research. The primary audience for this book is geared towards scientists and researchers with interest in cancer stem cells, stem cells, cell biology, neurobiology, and regenerative medicine.

Stem Cell Therapeutics for Cancer

Stem Cell Therapeutics for Cancer
Author: Khalid Shah
Publsiher: John Wiley & Sons
Total Pages: 304
Release: 2013-08-01
ISBN 10: 1118660625
ISBN 13: 9781118660621
Language: EN, FR, DE, ES & NL

Stem Cell Therapeutics for Cancer Book Review:

Stem Cell Therapeutics for Cancer covers theapplication of stem cells in various cancers, with an emphasis onthe aspects of these strategies that are critical to the success offuture stem cell-based therapies for cancer. Topics covered in thebook include stem cell sources, tumor specificity, targetedtherapeutics, visualizing the stem cell, and therapeutic agentpharmacokinetics. Each chapter contains a brief introduction to thecancer, followed by an exploration of how engineered stem cellshave been utilized to cure the disease in mouse models and in earlyphase clinical trials. Comprises of sections on stem cell therapy in brain cancers,lung cancers, breast cancers, as well as stem cells incombination with other therapies Focuses on the practical applications of using stem cells asgene delivery agents to treat cancer Includes coverage of cutting-edge molecular imaging techniquesin stem cell therapeutics for a variety of tumour types

Modulation of Human Immune Parameters by Anticancer Therapies

Modulation of Human Immune Parameters by Anticancer Therapies
Author: Ulrich Sack,Attila Tarnok,Il-Kang Na,Frank Preijers
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-01-18
ISBN 10: 288966399X
ISBN 13: 9782889663996
Language: EN, FR, DE, ES & NL

Modulation of Human Immune Parameters by Anticancer Therapies Book Review: