Biopharmaceutics and Pharmacokinetics Considerations

Biopharmaceutics and Pharmacokinetics Considerations
Author: Anonim
Publsiher: Academic Press
Total Pages: 752
Release: 2021-07-07
ISBN 10: 0128144262
ISBN 13: 9780128144268
Language: EN, FR, DE, ES & NL

Biopharmaceutics and Pharmacokinetics Considerations Book Review:

Biopharmaceutics and Pharmacokinetics Considerations examines the history of biopharmaceutics and pharmacokinetics. The book provides a biopharmaceutics and pharmacokinetics approach to addressing issues in formulation development and ethical considerations in handling animals. Written by experts in the field, this volume within the Advances in Pharmaceutical Product Development and Research series deepens understanding of biopharmaceutics and pharmacokinetics within drug discovery and drug development. Each chapter delves into a particular aspect of this fundamental field to cover the principles, methodologies and technologies employed by pharmaceutical scientists, researchers and pharmaceutical industries to study the chemical and physical properties of drugs and the biological effects they produce. Examines the most recent developments in biopharmaceutics and pharmacokinetics for pharmaceutical sciences Covers the principles, methodologies and technologies of biopharmaceutics and pharmacokinetics Focuses on the pharmaceutical sciences, but also encompasses aspects of toxicology, neuroscience, environmental sciences and nanotechnology

Pharmacokinetics and Toxicokinetic Considerations Vol II

Pharmacokinetics and Toxicokinetic Considerations   Vol II
Author: Rakesh Kumar Tekade
Publsiher: Academic Press
Total Pages: 814
Release: 2022-02-17
ISBN 10: 0323913164
ISBN 13: 9780323913164
Language: EN, FR, DE, ES & NL

Pharmacokinetics and Toxicokinetic Considerations Vol II Book Review:

Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists. Allows readers to systematically integrate up-to-date research findings into their laboratory work Presents focused explorations of bioanalytical methods for bioavailability and bioequivalence assessment Provides clinical applications of concepts

Applied Biopharmaceutics and Pharmacokinetics

Applied Biopharmaceutics and Pharmacokinetics
Author: Leon Shargel,Andrew B. C. Yu
Publsiher: McGraw-Hill/Appleton & Lange
Total Pages: 625
Release: 1993
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015029461012
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics and Pharmacokinetics Book Review:

The third edition of this introductory text covers the factors which influence the release of the drug from the drug product and how the body handles the drug. A stronger focus has been placed on the basics with clear explanations and illustrated examples. There is also more information on statistics and population pharmacokinetics and new chapters on drug distribution, computer applications, enzyme kinetics and pharmacokinetics models.

Applications of Pharmacokinetic Principles in Drug Development

Applications of Pharmacokinetic Principles in Drug Development
Author: Rajesh Krishna
Publsiher: Springer Science & Business Media
Total Pages: 550
Release: 2004
ISBN 10: 9780306477669
ISBN 13: 0306477661
Language: EN, FR, DE, ES & NL

Applications of Pharmacokinetic Principles in Drug Development Book Review:

This book presents a collection of articles that represent individual and expert perspectives in both preclinical and clinical development, including case studies on real-life examples of successful drugs that add value to the pharmacokinetic principles learned and applied. Unlike existing books that focus on pharmacokinetic theory, the current book emphasizes application of pharmacokinetic principles in new drug development.

Biopharmaceutics Pharmacokinetics

Biopharmaceutics   Pharmacokinetics
Author: Dr. A. R. Paradkar
Publsiher: Pragati Books Pvt. Ltd.
Total Pages: 150
Release: 2008-10-06
ISBN 10: 9788185790374
ISBN 13: 818579037X
Language: EN, FR, DE, ES & NL

Biopharmaceutics Pharmacokinetics Book Review:

Dosage Form Design Considerations

Dosage Form Design Considerations
Author: Anonim
Publsiher: Academic Press
Total Pages: 820
Release: 2018-07-28
ISBN 10: 0128144246
ISBN 13: 9780128144244
Language: EN, FR, DE, ES & NL

Dosage Form Design Considerations Book Review:

Dosage Form Design Parameters, Volume I, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. Examines the history and recent developments in drug dosage forms for pharmaceutical sciences Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Developing Solid Oral Dosage Forms

Developing Solid Oral Dosage Forms
Author: Yihong Qiu,Yisheng Chen,Geoff G.Z. Zhang,Lirong Liu,William Porter
Publsiher: Academic Press
Total Pages: 978
Release: 2009-03-10
ISBN 10: 9780080932729
ISBN 13: 008093272X
Language: EN, FR, DE, ES & NL

Developing Solid Oral Dosage Forms Book Review:

Developing Solid Oral Dosage Forms is intended for pharmaceutical professionals engaged in research and development of oral dosage forms. It covers essential principles of physical pharmacy, biopharmaceutics and industrial pharmacy as well as various aspects of state-of-the-art techniques and approaches in pharmaceutical sciences and technologies along with examples and/or case studies in product development. The objective of this book is to offer updated (or current) knowledge and skills required for rational oral product design and development. The specific goals are to provide readers with: Basics of modern theories of physical pharmacy, biopharmaceutics and industrial pharmacy and their applications throughout the entire process of research and development of oral dosage forms Tools and approaches of preformulation investigation, formulation/process design, characterization and scale-up in pharmaceutical sciences and technologies New developments, challenges, trends, opportunities, intellectual property issues and regulations in solid product development The first book (ever) that provides comprehensive and in-depth coverage of what's required for developing high quality pharmaceutical products to meet international standards It covers a broad scope of topics that encompass the entire spectrum of solid dosage form development for the global market, including the most updated science and technologies, practice, applications, regulation, intellectual property protection and new development trends with case studies in every chapter A strong team of more than 50 well-established authors/co-authors of diverse background, knowledge, skills and experience from industry, academia and regulatory agencies

Biopharmaceutics Applications in Drug Development

Biopharmaceutics Applications in Drug Development
Author: Rajesh Krishna,Lawrence Yu
Publsiher: Springer Science & Business Media
Total Pages: 396
Release: 2007-09-20
ISBN 10: 038772379X
ISBN 13: 9780387723792
Language: EN, FR, DE, ES & NL

Biopharmaceutics Applications in Drug Development Book Review:

The highly experienced authors here present readers with step-wise, detail-conscious information to develop quality pharmaceuticals. The book is made up of carefully crafted sections introducing key concepts and advances in the areas of dissolution, BA/BE, BCS, IVIC, and product quality. It provides a specific focus on the integration of regulatory considerations and includes case histories highlighting the biopharmaceutics strategies adopted in development of successful drugs.

Clinical Trials of Drugs and Biopharmaceuticals

Clinical Trials of Drugs and Biopharmaceuticals
Author: Chi-Jen Lee,Lucia H. Lee,Christopher L. Wu,Benjamin R. Lee,Mei-Ling Chen
Publsiher: CRC Press
Total Pages: 520
Release: 2005-09-19
ISBN 10: 1420039148
ISBN 13: 9781420039146
Language: EN, FR, DE, ES & NL

Clinical Trials of Drugs and Biopharmaceuticals Book Review:

The pharmaceutical industry is on the verge of an exciting and challenging century. Advances in pharmaceutical sciences have dramatically changed the processes of discovery and development of new therapeutic drugs and, in turn, resulted in an extraordinary increase in the potential prophylactic and therapeutic interventions. In this atmosphere, an

Biopharmaceutics and Clinical Pharmacokinetics

Biopharmaceutics and Clinical Pharmacokinetics
Author: Notari
Publsiher: Routledge
Total Pages: 440
Release: 2017-11-22
ISBN 10: 1351463845
ISBN 13: 9781351463843
Language: EN, FR, DE, ES & NL

Biopharmaceutics and Clinical Pharmacokinetics Book Review:

For a decade and a half, Biopharmaceutics and Clinical Pharmacokinetics has been used in theclassrooms around the world as an introductory textbook on biophannaceutics and phannacokinetics.Now, the new Fourth Edition, Revised and Expanded further enhances the preceding editions'proven features, introducing significant advances in clinical pharmacokinetics, pharmacokineticdesign of drugs and dosage forms, and model-independent analyses.Still usable without prior knowledge of calculus or kinetics, this successfully implemented workbookmaintains a carefully graduated "building block" presentation, incorporating sample problemsand exercises throughout for a thorough understanding of the material.Biopharmaceutics and Clinical Pharmacokinetics features a growth-oriented format that systematicallydevelops and interrelates all subject matter .. . introduces basic theory and fields of application... emphasizes model-independent pharmacokinetic analyses ... presents biopharmaceutical aspectsof product design and evaluation .. . offers a unique approach to teaching dosage regimen design andindividualization . .. and considers structural modification of drug molecules for problems associatedwith pharmacokinetics.As a comprehensive coverage of the basic principles and the recent achievements in the field, noother textbook does as much for students of pharmacy, pharmacology, medicinal chemistry, andmedicine, or for scientists who desire a simple but thorough introduction to theory and application.

Biopharmaceutics

Biopharmaceutics
Author: Hannah Batchelor
Publsiher: John Wiley & Sons
Total Pages: 320
Release: 2021-12-13
ISBN 10: 1119678374
ISBN 13: 9781119678373
Language: EN, FR, DE, ES & NL

Biopharmaceutics Book Review:

Explore the latest research in biopharmaceutics from leading contributors in the field In Biopharmaceutics - From Fundamentals to Industrial Practice, distinguished Scientists from the UK's Academy of Pharmaceutical Sciences Biopharmaceutica Focus Group deliver a comprehensive examination of the tools used within the field of biopharmaceutics and their applications to drug development. This edited volume is an indispensable tool for anyone seeking to better understand the field of biopharmaceutics as it rapidly develops and evolves. Beginning with an expansive introduction to the basics of biopharmaceutics and the context that underpins the field, the included resources go on to discuss how biopharmaceutics are integrated into product development within the pharmaceutical industry. Explorations of how the regulatory aspects of biopharmaceutics function, as well as the impact of physiology and anatomy on the rate and extent of drug absorption, follow. Readers will find insightful discussions of physiologically based modeling as a valuable asset in the biopharmaceutics toolkit and how to apply the principles of the field to special populations. The book goes on to discuss: Thorough introductions to biopharmaceutics, basic pharmacokinetics, and biopharmaceutics measures Comprehensive explorations of solubility, permeability, and dissolution Practical discussions of the use of biopharmaceutics to inform candidate drug selection and optimization, as well as biopharmaceutics tools for rational formulation design In-depth examinations of biopharmaceutics classification systems and regulatory biopharmaceutics, as well as regulatory biopharmaceutics and the impact of anatomy and physiology Perfect for professionals working in the pharmaceutical and biopharmaceutical industries, Biopharmaceutics - From Fundamentals to Industrial Practice is an incisive and up-to-date resource on the practical, pharmaceutical applications of the field.

Basic Pharmacokinetics Second Edition

Basic Pharmacokinetics  Second Edition
Author: Mohsen A. Hedaya
Publsiher: CRC Press
Total Pages: 595
Release: 2012-02-09
ISBN 10: 1439850739
ISBN 13: 9781439850732
Language: EN, FR, DE, ES & NL

Basic Pharmacokinetics Second Edition Book Review:

Knowledge of pharmacokinetics is critical to understanding the absorption, distribution, metabolism, and excretion of drugs. It is therefore vital to those engaged in the discovery, development, and preclinical and clinical evaluation of drugs, as well as practitioners involved in the clinical use of drugs. Using different approaches accessible to a wide variety of readers, Basic Pharmacokinetics: Second Edition demonstrates the quantitative pharmacokinetic relations and the interplay between pharmacokinetic parameters. After a basic introduction to pharmacokinetics and its related fields, the book examines: Mathematical operations commonly used in pharmacokinetics Drug distribution and clearance and how they affect the rate of drug elimination after a single dose Factors affecting drug absorption following extravascular drug administration, the rate and extent of drug absorption, and drug bioequivalence The steady-state concept during constant rate intravenous infusion and during multiple drug administration Renal drug elimination, drug metabolism, multicompartment models, nonlinear pharmacokinetics, and drug administration by intermittent intravenous infusion Pharmacokinetic-pharmacodynamic modeling, noncompartmental pharmacokinetic data analysis, clearance concept from the physiological point of view, and physiological modeling Clinical applications of pharmacokinetics, including therapeutic drug monitoring, drug pharmacokinetics in special populations, pharmacokinetic drug-drug interactions, pharmacogenomics, and applications of computers in pharmacokinetics Accompanying the book is a CD-ROM with self-instructional tutorials and pharmacokinetic and pharmacokinetic-pharmacodynamic simulations, allowing visualization of concepts for enhanced comprehension. This learning tool received an award from the American Association of Colleges of Pharmacy for innovation in teaching, making it a valuable supplement to this essential text.

Applied Biopharmaceutics Pharmacokinetics

Applied Biopharmaceutics   Pharmacokinetics
Author: Leon Shargel,Andrew B. C. Yu
Publsiher: McGraw-Hill/Appleton & Lange
Total Pages: 768
Release: 1999
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015046909456
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics Pharmacokinetics Book Review:

This new edition emphasizes the application and understanding of basic theoretical principles of biopharmaceutics and pharmacokinetics. Now with a second highlight color, this book helps students gain skills in problem solving and includes examples and practice problems and solutions.

Preclinical Safety Evaluation of Biopharmaceuticals

Preclinical Safety Evaluation of Biopharmaceuticals
Author: Joy A. Cavagnaro
Publsiher: John Wiley & Sons
Total Pages: 1064
Release: 2013-03-07
ISBN 10: 1118679385
ISBN 13: 9781118679388
Language: EN, FR, DE, ES & NL

Preclinical Safety Evaluation of Biopharmaceuticals Book Review:

"The goal is to provide a comprehensive reference book for thepreclinicaldiscovery and development scientist whoseresponsibilities span target identification, lead candidateselection, pharmacokinetics, pharmacology, and toxicology, and forregulatory scientists whose responsibilities include the evaluationof novel therapies." —From the Afterword by Anthony D. Dayan Proper preclinical safety evaluation can improve the predictivevalue, lessen the time and cost of launching newbiopharmaceuticals, and speed potentially lifesaving drugs tomarket. This guide covers topics ranging from lead candidateselection to establishing proof of concept and toxicity testing tothe selection of the first human doses. With chapters contributedby experts in their specific areas, Preclinical SafetyEvaluation of Biopharmaceuticals: A Science-Based Approach toFacilitating Clinical Trials: Includes an overview of biopharmaceuticals with information onregulation and methods of production Discusses the principles of ICH S6 and their implementation inthe U.S., Europe, and Japan Covers current practices in preclinical development andincludes a comparison of safety assessments for small moleculeswith those for biopharmaceuticals Addresses all aspects of the preclinical evaluation process,including: the selection of relevant species; safety/toxicityendpoints; specific considerations based upon class; and practicalconsiderations in the design, implementation, and analysis ofbiopharmaceuticals Covers transitioning from preclinical development to clinicaltrials This is a hands-on, straightforward reference for professionalsinvolved in preclinical drug development, including scientists,toxicologists, project managers, consultants, and regulatorypersonnel.

Rowland and Tozer s Clinical Pharmacokinetics and Pharmacodynamics Concepts and Applications

Rowland and Tozer s Clinical Pharmacokinetics and Pharmacodynamics  Concepts and Applications
Author: Hartmut Derendorf,Stephan Schmidt
Publsiher: Lippincott Williams & Wilkins
Total Pages: 864
Release: 2019-07-11
ISBN 10: 1496385896
ISBN 13: 9781496385895
Language: EN, FR, DE, ES & NL

Rowland and Tozer s Clinical Pharmacokinetics and Pharmacodynamics Concepts and Applications Book Review:

Updated with the latest clinical advances, Rowland and Tozer’s Clinical Pharmacokinetics and Pharmacodynamics, Fifth Edition , explains the relationship between drug administration and drug response, taking a conceptual approach that emphasizes clinical application rather than science and mathematics. Bringing a real-life perspective to the topic, the book simplifies concepts and gives readers the knowledge they need to better evaluate drug applications.

Atkinson s Principles of Clinical Pharmacology

Atkinson s Principles of Clinical Pharmacology
Author: Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson, Jr.
Publsiher: Academic Press
Total Pages: 762
Release: 2021-10-16
ISBN 10: 0128198842
ISBN 13: 9780128198841
Language: EN, FR, DE, ES & NL

Atkinson s Principles of Clinical Pharmacology Book Review:

Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Applied Biopharmaceutics Pharmacokinetics Sixth Edition

Applied Biopharmaceutics   Pharmacokinetics  Sixth Edition
Author: Leon Shargel,Andrew Yu,Susanna Wu-Pong
Publsiher: McGraw Hill Professional
Total Pages: 811
Release: 2012-12-22
ISBN 10: 0071603948
ISBN 13: 9780071603942
Language: EN, FR, DE, ES & NL

Applied Biopharmaceutics Pharmacokinetics Sixth Edition Book Review:

A comprehensive textbook on the theoretical and practical applications of biopharmaceutics and pharmacokinetics The field’s leading text for more than three decades Applied Biopharmaceutics & Pharmacokinetics, Sixth Edition provides you with a basic understanding of the principles of biopharmaceutics and pharmacokinetics and applies these principles to drug product development, drug product performance and drug therapy. The revised and updated sixth edition is unique in teaching basic concepts that relate to understanding the complex issues associated with safe and efficacious drug therapy. Written by authors who have both academic and clinical experience, Applied Biopharmaceutics & Pharmacokinetics will help you to: Understand the basic concepts in biopharmaceutics and pharmacokinetics. Use raw data and derive the pharmacokinetic models and parameters that best describe the process of drug absorption, distribution, and elimination Critically evaluate biopharmaceutic studies involving drug product equivalency and unequivalency Design and evaluate dosage regimens of drugs, using pharmacokinetic and biopharmaceutic parameters Detect potential clinical pharmacokinetic problems and apply basic pharmacokinetic principles to solve them Practical problems and clinical examples with discussions are included in each chapter to help you apply these principles to patient care and drug consultation situations. Chapter Objectives, Chapter Summaries, and Frequently Asked Questions along with additional application questions appear within each chapter to identify and focus on key concepts. Most of the chapters have been revised to reflect our current understanding of drug product performance, bioavailability, bioequivalence, pharmacokinetics, pharmacodynamics, and drug therapy.

Pharmaceutical Dosage Forms and Drug Delivery Systems

Pharmaceutical Dosage Forms and Drug Delivery Systems
Author: Howard C. Ansel,Loyd V. Allen,Nicholas G. Popovich
Publsiher: Lippincott Williams & Wilkins
Total Pages: 595
Release: 1999
ISBN 10: 9780683305722
ISBN 13: 0683305727
Language: EN, FR, DE, ES & NL

Pharmaceutical Dosage Forms and Drug Delivery Systems Book Review:

eaders will find this book to be the most comprehensive source on pharmaceutical dosage forms and drug delivery systems. Physical Pharmacy Capsules highlight key concepts with boxes, providing easy reference. Reflecting traditional pharmaceutics pedagogy, the new edition is organized by dosage form rather than by route of administration

Pharmaceutical Biotechnology

Pharmaceutical Biotechnology
Author: Daan J. A. Crommelin,Robert D. Sindelar
Publsiher: CRC Press
Total Pages: 456
Release: 2002-11-14
ISBN 10: 9780415285018
ISBN 13: 0415285011
Language: EN, FR, DE, ES & NL

Pharmaceutical Biotechnology Book Review:

The field of pharmaceutical biotechnology is evolving rapidly. A whole new arsenal of protein pharmaceuticals is being produced by recombinant techniques for cancer, viral infections, cardiovascular and hereditary disorders, and other diseases. In addition, scientists are confronted with new technologies such as polymerase chain reactions, combinatorial chemistry and gene therapy. This introductory textbook provides extensive coverage of both the basic science and the applications of biotechnology-produced pharmaceuticals, with special emphasis on their clinical use. Pharmaceutical Biotechnology serves as a complete one-stop source for undergraduate pharmacists, and it is valuable for researchers and professionals in the pharmaceutical industry as well.

Comparative Pharmacokinetics

Comparative Pharmacokinetics
Author: Jim E. Riviere
Publsiher: John Wiley & Sons
Total Pages: 432
Release: 2011-01-14
ISBN 10: 9780470959886
ISBN 13: 0470959886
Language: EN, FR, DE, ES & NL

Comparative Pharmacokinetics Book Review:

Now in a revised edition, Comparative Pharmacokinetics: Principles, Techniques, and Applications presents the principles and techniques of comparative and veterinary pharmacokinetics in a detailed yet practical manner. Developed as a tool for ensuring that pharmacokinetics studies are properly designed and correctly interpreted, the book provides complete coverage of the conceptual basis of pharmacokinetics as used for quantifying biological processes from the perspectives of physiology and medicine. New chapters have been added on quantitative structure permeability relationships and bioequivalence, and a number of existing chapters have been significantly revised and expanded to provide a current resource for veterinary and comparative pharmacokinetics.