Biomarkers in Bipolar Disorders

Biomarkers in Bipolar Disorders
Author: Rodrigo Machado-Vieira,Jair Soares
Publsiher: Academic Press
Total Pages: 528
Release: 2022-01-16
ISBN 10: 012821399X
ISBN 13: 9780128213995
Language: EN, FR, DE, ES & NL

Biomarkers in Bipolar Disorders Book Review:

Biomarkers in Bipolar Disorders summarizes cutting-edge findings in biomarkers' research, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings cover different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes), prediction of treatment response and follow-up outcomes, along with the most promising perspectives in each area. Each section includes a comprehensive and focused overview on the state-of-the-art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder. Describes strategies for the biomarker discovery of relevant proteins differentially expressed in Bipolar Disorder Presents techniques and main findings in transcriptome research related to CNS synaptic function Provides an overview on current behavioral strategies and their validity in drug development in Bipolar Disorder Discusses current genetic findings, integrating tests for treatments leading to personalized treatments

Biomarkers of Postpartum Psychiatric Disorders

Biomarkers of Postpartum Psychiatric Disorders
Author: Jennifer L. Payne,Lauren M. Osborne
Publsiher: Academic Press
Total Pages: 236
Release: 2019-09-28
ISBN 10: 0128158360
ISBN 13: 9780128158364
Language: EN, FR, DE, ES & NL

Biomarkers of Postpartum Psychiatric Disorders Book Review:

Biomarkers of Postpartum Psychiatric Disorders provides an up-to-date reference on the current research relating to biomarkers in psychiatric disorders, including major depressive disorder, OCD and bipolar disorder in the immediate postpartum time-period. It is the only reference on the market that synthesizes and interprets available data and reviews clinical phenotypes. Topics cover hormonal contributions, immunology, epigenetics and neuroimaging. While the risk of psychiatric illness during pregnancy appears to be equivalent to the risk at any other time in a woman’s life, the risk in the immediate postpartum time period is dramatically increased, hence the importance of the discussions in this title. Identifies epigenetic, hormonal, immunological and neuroimaging biomarkers Provides biomarkers for depression, OCD and psychosis Includes clinical phenotypes for psychiatric disorders Discusses future research and directions in the field

Genetic Mechanisms of Biomarkers in Schizophrenia Bipolar Disorder and Depression

Genetic Mechanisms of Biomarkers in Schizophrenia  Bipolar Disorder and Depression
Author: Hongsheng Gui,Shaohua Hu,Qiang Wang,Xiancang Ma,Sarah Tarbox-Berry
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-02-01
ISBN 10: 2889714381
ISBN 13: 9782889714384
Language: EN, FR, DE, ES & NL

Genetic Mechanisms of Biomarkers in Schizophrenia Bipolar Disorder and Depression Book Review:

Biomarkers in Bipolar Disorders

Biomarkers in Bipolar Disorders
Author: Rodrigo Machado-Vieira,Jair Soares
Publsiher: Elsevier
Total Pages: 528
Release: 2022-02-03
ISBN 10: 0128213981
ISBN 13: 9780128213988
Language: EN, FR, DE, ES & NL

Biomarkers in Bipolar Disorders Book Review:

Nearly 5.7 million adult Americans are affected by bipolar disorder according to the National Institute of Mental Health. Bipolar disorder (BD) is a recurrent chronic disorder characterized by fluctuations in mood. Those suffering from bipolar disorder are at crossroads, suffering a major personal, social and economic burden. Currently, there lacks of definitive diagnostic tools for psychiatric disorders. Psychiatry continues to rely on a non-biologically based, diagnostic classification. Identification of biologically relevant markers could improve the quality of life of patients with bipolar disorder and revolutionize public health. Biomarkers in Bipolar Disorders summarizes the cutting-edge findings in biomarkers research in Bipolar Disorders, emphasizing the most promising findings, tools and technologies relevant to drug development and personalized medicine. Key findings emphasizing different levels of evidence such as genes, molecules, cells, systems, brain and behavior related to diagnosis (state and trait/endophenotypes), prediction of treatment response and follow-up outcomes with as well as the most promising perspectives in each area are included in the book. Each section includes a comprehensive and focused overview on the state of the art and perspectives. The book concludes with a section on practical applications, encompassing diagnostics development (genetic testing, biomarkers), and new drug development. Edited by Dr. Rodrigo Machado-Vieira and Dr. Jair C. Soares, and contributed by leading experts in the field of biomarker research, this book will be become the leading tool for all researchers and clinicians in Bipolar Disorder.

Neuroprogression in Psychiatry

Neuroprogression in Psychiatry
Author: Flávio Kapczinski,Michael Berk,Pedro Vieira da Silva Magalhães
Publsiher: Oxford University Press
Total Pages: 272
Release: 2019-03-05
ISBN 10: 0191090883
ISBN 13: 9780191090882
Language: EN, FR, DE, ES & NL

Neuroprogression in Psychiatry Book Review:

Recent studies regarding the neuropathology of specific neurological disorders suggest that both neurodevelopmental and neurodegenerative processes may play a role. However, in contrast to the neurodegeneration seen in neurological disorders such as Parkinson's and Alzheimer's disease, the term "neuroprogression" has been used to describe the neurodevelopmental aspect of pathological brain re-wiring that takes place in the context of severe psychiatric disorders, such as schizophrenia or bipolar disorder. Within psychiatry, patients with severe psychopathology, such as those depressed patients who eventually commit suicide, have been shown to present with increased inflammatory markers in the brain. A similar increase in inflammatory markers is also found in patients with bipolar disorders and schizophrenia. Thus, oxidative stress, inflammation, and changes in growth factors are thought to be the pathways of neuroprogression. Neuroprogression in Psychiatry provides a comprehensive summary of the current developments in the emerging field of neuroprogression. With contributions by leading researchers in the field, this book examines the role of neuroprogression across a wide range of specific psychiatric disorders, with chapters included on major depressive disorder, anxiety disorder, post-traumatic stress disorder, substance abuse, schizophrenia, and bipolar disorder.

Neurobiology of Bipolar Disorder

Neurobiology of Bipolar Disorder
Author: Joao Luciano de Quevedo,Andre Ferrer Carvalho,Eduard Vieta
Publsiher: Academic Press
Total Pages: 470
Release: 2020-11-25
ISBN 10: 012819183X
ISBN 13: 9780128191835
Language: EN, FR, DE, ES & NL

Neurobiology of Bipolar Disorder Book Review:

The Neurobiology of Bipolar Disorder: Road to Novel Therapeutics combines the basic neurobiology of bipolar disorder with discussions of the most recent advances in research, including the interacting pathways implicated in the pathophysiology of bipolar disorder, genetic approaches and the pharmacogenomics of bipolar disorder. The basic foundational understanding of the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research combine to aid advanced students and researchers in their understanding of bipolar disorder management using novel and fast-acting pharmaceutical and neuromodulatory approaches. Aids readers in understanding bipolar disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments to novel therapeutics Synthesizes a discussion of the cellular and molecular mechanisms underlying symptoms with clinical aspects of bipolar disorder

Biomarkers in Psychiatry

Biomarkers in Psychiatry
Author: Judith Pratt,Jeremy Hall
Publsiher: Springer
Total Pages: 437
Release: 2019-01-05
ISBN 10: 3319996428
ISBN 13: 9783319996424
Language: EN, FR, DE, ES & NL

Biomarkers in Psychiatry Book Review:

This volume addresses one of the Holy Grails in Psychiatry, namely the evidence for and potential to adopt ‘Biomarkers’ for prevention, diagnosis, and treatment responses in mental health conditions. It meshes together state of the art research from international renowned pre-clinical and clinical scientists to illustrate how the fields of anxiety disorders, depression, psychotic disorders, and autism spectrum disorder have advanced in recent years.

Personalized Psychiatry

Personalized Psychiatry
Author: Bernhard Baune
Publsiher: Academic Press
Total Pages: 604
Release: 2019-10-16
ISBN 10: 0128131772
ISBN 13: 9780128131770
Language: EN, FR, DE, ES & NL

Personalized Psychiatry Book Review:

Personalized Psychiatry presents the first book to explore this novel field of biological psychiatry that covers both basic science research and its translational applications. The book conceptualizes personalized psychiatry and provides state-of-the-art knowledge on biological and neuroscience methodologies, all while integrating clinical phenomenology relevant to personalized psychiatry and discussing important principles and potential models. It is essential reading for advanced students and neuroscience and psychiatry researchers who are investigating the prevention and treatment of mental disorders. Combines neurobiology with basic science methodologies in genomics, epigenomics and transcriptomics Demonstrates how the statistical modeling of interacting biological and clinical information could transform the future of psychiatry Addresses fundamental questions and requirements for personalized psychiatry from a basic research and translational perspective

The Search for Biomarkers in Psychiatry

The Search for Biomarkers in Psychiatry
Author: Jorge Manzanares,Maria S. Garcia-Gutierrez,Francisco Navarrete Rueda,Piotr Gałecki
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-09-14
ISBN 10: 2889713016
ISBN 13: 9782889713011
Language: EN, FR, DE, ES & NL

The Search for Biomarkers in Psychiatry Book Review:

The Bipolar Book

The Bipolar Book
Author: Aysegül Yildiz
Publsiher: Oxford University Press, USA
Total Pages: 704
Release: 2015-05-28
ISBN 10: 0199300534
ISBN 13: 9780199300532
Language: EN, FR, DE, ES & NL

The Bipolar Book Book Review:

As a major mainstay of clinical focus and research today, bipolar disorder affects millions of individuals across the globe with its extreme and erratic shifts of mood, thinking and behavior. Edited by a team of experts in the field, The Bipolar Book: History, Neurobiology, and Treatment is a testament and guide to diagnosing and treating this exceedingly complex, highly prevalent disease. Featuring 45 chapters from an expert team of contributors from around the world, The Bipolar Book delves deep into the origins of the disorder and how it informs clinical practice today by focusing on such topics as bipolar disorder occurring in special populations, stigmatization of the disease, the role genetics play, postmortem studies, psychotherapy, treatments and more. Designed to be the definitive reference volume for clinicians, students and researchers, Aysegül Yildiz, Pedro Ruiz and Charles Nemeroff present The Bipolar Book as a "must have" for those caregivers who routinely deal with this devastating disease.

Neuroprogression and Staging in Bipolar Disorder

Neuroprogression and Staging in Bipolar Disorder
Author: Flávio Kapczinski,Eduard Vieta,Pedro V. S. Magalhães,Michael Berk
Publsiher: Oxford University Press, USA
Total Pages: 344
Release: 2015
ISBN 10: 0198709994
ISBN 13: 9780198709992
Language: EN, FR, DE, ES & NL

Neuroprogression and Staging in Bipolar Disorder Book Review:

Provides a solid and in-depth outline that can be used to influence research and practice in the field of bipolar disorder. This book would be of use to anyone working with mood disorders, and serves as a valuable resource for both researchers interested in bipolar disorder and clinicians involved in the day-to-day management of patientswithh this condition.--

The Science and Practice of Lithium Therapy

The Science and Practice of Lithium Therapy
Author: Gin S. Malhi,Marc Masson,Frank Bellivier
Publsiher: Springer
Total Pages: 342
Release: 2016-11-24
ISBN 10: 3319459236
ISBN 13: 9783319459233
Language: EN, FR, DE, ES & NL

The Science and Practice of Lithium Therapy Book Review:

This book provides a clear and comprehensive guide to the clinical prescription of lithium that draws upon evidence-based knowledge of its mechanisms of action. The book is divided into two parts, on the science of lithium and the practice of lithium therapy. The former covers aspects such as the properties of the lithium ion, pharmacokinetics and pharmacodynamics, impact on neurotransmission, and gene expression modulation. The section on practice includes discussion of variability in response to lithium, use of lithium in the treatment of bipolar disorders, its value in suicide prevention, administration during pregnancy and in the pediatric age group, and side effects. Lithium is arguably the only true mood stabilizer, and its multifaceted effects across many clinical domains have given rise to a resurgence of interest in recent years, fuelled by both researchers and clinicians. Nevertheless, its use remains constrained by exaggerated concerns about potential side-effects. In reality, lithium is a simple molecule that is relatively straightforward to administer and monitor and has potentially profound benefits at a fraction of the cost of contemporary agents. This book dispels the many myths and concerns that surround its use and will be of interest for clinicians and researchers worldwide, and those that are recipients of lithium therapy.

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide
Author: Yogesh Dwivedi
Publsiher: CRC Press
Total Pages: 482
Release: 2012-06-25
ISBN 10: 143983881X
ISBN 13: 9781439838815
Language: EN, FR, DE, ES & NL

The Neurobiological Basis of Suicide Book Review:

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders
Author: Paul C. Guest
Publsiher: Springer
Total Pages: 328
Release: 2019-02-12
ISBN 10: 3030055426
ISBN 13: 9783030055424
Language: EN, FR, DE, ES & NL

Reviews on Biomarker Studies in Psychiatric and Neurodegenerative Disorders Book Review:

This book includes a series of reviews on general aspects of biomarker use in the study of psychiatric and neurodegenerative diseases and the development of medications involved in their treatment. It describes the pros and cons of the various approaches and covers the successes and failures in this research field. It is only by a thorough understanding of the shortcomings that progress can be made. The overall goal is to facilitate the understanding and treatment of these disorders, by providing a viable mechanism of catching up with other areas of modern medicine, such as diabetes and heart disease. Finally, it is anticipated that the development and application of valid biomarker tests and the leveraging of novel drug targets will help the fields of psychiatry on neurodegenerative disorders move into the area of personalized medicine where the right patients can receive the right medication at the right time for the best possible outcome.

Immuno Psychiatry

Immuno Psychiatry
Author: Michael Berk,Marion Leboyer,Iris E. Sommer
Publsiher: Springer Nature
Total Pages: 444
Release: 2021-08-14
ISBN 10: 303071229X
ISBN 13: 9783030712297
Language: EN, FR, DE, ES & NL

Immuno Psychiatry Book Review:

This book presents a thorough and critical review of current knowledge on the role of immunology in major psychiatric disorders and its potential applications. The opening chapters offer general information on the immune influence of the brain to provide readers with a better understanding of the end of immune privilege. The book then examines possible underlying mechanisms leading to psychiatric disorders, from early infections to pro-inflammatory markers, stress, and immune genetic background, linking etiology and psychiatry. The third section describes each disorder (ie autism, schizophrenia, bipolar disorder, depression...) with an overview of underlying immune dysfunctions. Lastly, the authors discuss the innovative immune-therapies that may result from the discovery of immune system biomarkers and their associated mechanisms. A better understanding of the role of the immune system in psychiatric disorders makes it possible to identify stratification biomarkers, to explain underlying mechanisms, and to develop innovative, efficient, targeted treatment strategies and management. As such, the book is of value to clinicians, mental health professionals, mental health researchers, immunologists, industry practitioners, and various stakeholders in the mental health field.

Mood Disorders

Mood Disorders
Author: Sudhakar Selvaraj,Paolo Brambilla,Jair C. Soares
Publsiher: Cambridge University Press
Total Pages: 294
Release: 2021-01-07
ISBN 10: 110842712X
ISBN 13: 9781108427128
Language: EN, FR, DE, ES & NL

Mood Disorders Book Review:

Offering up-to-date information on brain imaging in mood disorders, this book is an invaluable resource for mental health professionals.

Advances in Treatment of Bipolar Disorders

Advances in Treatment of Bipolar Disorders
Author: Edited by Terence A. Ketter M.D.
Publsiher: American Psychiatric Pub
Total Pages: 338
Release: 2015-04-09
ISBN 10: 1585624179
ISBN 13: 9781585624171
Language: EN, FR, DE, ES & NL

Advances in Treatment of Bipolar Disorders Book Review:

Advances in Treatment of Bipolar Disorders provides clinicians with a well-written and timely guide to the most recent advances in the treatment of patients with this complex disorder. Staying abreast of new research developments and treatment options presents a daunting challenge, but the editor and coauthors have compiled the most important evidence-based findings from controlled studies and U.S. Food and Drug Administration approved indications, facilitating integration of these findings into clinical practice. This volume strives to provide clinicians with the necessary information to enable them to balance the likelihood of benefit (using “number needed to treat” analyses) versus harm (using “number needed to harm” analyses) in order to provide individualized, state-of-the-art, evidence-based care. The most current research findings are complemented by the authors’ extensive personal clinical experiences, resulting in a volume that reflects the most up-to-date thinking about the diagnosis and management of bipolar disorder. Advances in Treatment of Bipolar Disorders belongs in every mental health clinician’s library.

Psychiatric Genomics

Psychiatric Genomics
Author: Evangelia Eirini Tsermpini,Martin Alda,George P. Patrinos
Publsiher: Academic Press
Total Pages: 418
Release: 2022-03-18
ISBN 10: 0128214007
ISBN 13: 9780128214008
Language: EN, FR, DE, ES & NL

Psychiatric Genomics Book Review:

Psychiatric Genomics presents and synthesizes available knowledge in the field of psychiatric genomics, offering methodologies to advance new research and aid clinical translation. After providing an introduction to genomics and psychiatry, international experts discuss the genomic basis of schizophrenia, bipolar disorder, depression, personality disorders, anxiety disorders, addictions, eating disorders, and sleep disorders, among other disorders. In addition, recommendations for next steps in clinical implementation and drug discovery are discussed in-depth, with chapters dedicated to pharmacogenomics and antipsychotics, antidepressants and mood stabilizers, adverse drug reactions, implementation of pharmacogenomics in psychiatric clinics, and ethical issues. Finally, methods sections provide a solid grounding in research approaches and computational analytics, from using animal models in psychiatric genomics and accessing biobanks, to employing computational analysis, genome-wide association studies (GWAS), brain pathophysiology, and endophenotypes in psychiatric research. Thoroughly examines the genetic mechanisms underlying a broad range of psychiatric disorders Offers genomic methodologies and analytical approaches supporting new research and clinical translation, including personalized diagnosis and treatment models Features chapter contributions from international leaders in the field

Overdiagnosis in Psychiatry

Overdiagnosis in Psychiatry
Author: Joel Paris
Publsiher: Oxford University Press, USA
Total Pages: 240
Release: 2020
ISBN 10: 0197504272
ISBN 13: 9780197504277
Language: EN, FR, DE, ES & NL

Overdiagnosis in Psychiatry Book Review:

"This book, now revised in a section edition, examines the problem of over-diagnosis in psychiatry, focusing on problems with current diagnostic systems. It will show that diagnosis is not always a good guide to treatment selection, and that diagnoses have bee expanded in scope to justify currently popular methods of pharmacotherapy or psychotherapy. The most important categories that are over-diagnosed are bipolar disorders, major depression, attention-deficit hyperactivity disorder, and post-traumatic stress disorder. The boundary of pathology and normality remains unclear. This edition will also discuss dimensional systems that are transdiagnostic, and show how over-diagnosis is linked to the practice of aggressive psychopharmacology"--

Bipolar Disorder

Bipolar Disorder
Author: Nickolas B. Moore
Publsiher: Nova Science Pub Incorporated
Total Pages: 201
Release: 2013-01-01
ISBN 10: 9781626186668
ISBN 13: 1626186669
Language: EN, FR, DE, ES & NL

Bipolar Disorder Book Review:

Bipolar disorder is a psychiatric disease that involves profound changes in mood accompanied by severe changes in feelings, thoughts and behaviors wherein emotions can move quickly from a deep depression to excessive excitement without apparent reason. In this book, the authors present current research in the study of the symptoms, management and risk factors of bipolar disorder. Topics include face emotion processing deficits in pediatric bipolar disorder; understanding bipolar disorder from clinical expression to therapeutic strategies; brain-derived neurotrophic factors and neurocognitive profiles in the psychosis spectrum; understanding lived experience and personal recovery in people with bipolar disorder; computerized self-management in bipolar disorder; prescription drug Memantine in the long-term prophylaxis of treatment-resistant bipolar mood disorders; P11 expression and PET as potential biomarkers for bipolar disorder; and neurocognitive impairment in bipolar disorder.