Atkinson s Principles of Clinical Pharmacology

Atkinson s Principles of Clinical Pharmacology
Author: Shiew-Mei Huang,Juan J.L. Lertora,Paolo Vicini,Arthur J. Atkinson, Jr.
Publsiher: Academic Press
Total Pages: 762
Release: 2021-10-16
ISBN 10: 0128198842
ISBN 13: 9780128198841
Language: EN, FR, DE, ES & NL

Atkinson s Principles of Clinical Pharmacology Book Review:

Atkinson’s Principles of Clinical Pharmacology, Fourth Edition is the essential reference on the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This well-regarded survey continues to focus on the basics of clinical pharmacology for the development, evaluation and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the fourth edition has been thoroughly updated to provide readers with an ideal reference on the wide range of important topics impacting clinical pharmacology. Presents the essential knowledge for effective practice of clinical pharmacology Includes a new chapter and extended discussion on the role of personalized and precision medicine in clinical pharmacology Offers an extensive regulatory section that addresses US and international issues and guidelines Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers, along with further discussion on "Phase 0" studies (microdosing) and PBPK

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
Author: Arthur J. Atkinson, Jr.,Darrell R. Abernethy,Charles E. Daniels,Robert Dedrick,Sanford P. Markey
Publsiher: Elsevier
Total Pages: 568
Release: 2011-04-28
ISBN 10: 9780080466422
ISBN 13: 0080466427
Language: EN, FR, DE, ES & NL

Principles of Clinical Pharmacology Book Review:

This revised second edition covers the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development, focusing on the fundamentals that underlie the clinical use and contemporary development of pharmaceuticals. Authors drawn from academia, the pharmaceutical industry and government agencies cover the spectrum of material, including pharmacokinetic practice questions, covered by the basic science section of the certifying examination offered by the American Board of Clinical Pharmacology. This unique reference is recommended by the Board as a study text and includes modules on drug discovery and development to assist students as well as practicing pharmacologists. Unique breadth of coverage ranging from drug discovery and development to individualization and quality assessment of drug therapy Unusual cohesive of presentation that stems from author participation in an ongoing popular NIH course Instructive linkage of pharmacokinetic theory and applications with provision of sample problems for self-study Wide-ranging perspective of authors drawn from the ranks of Federal agencies, academia and the pharmaceutical industry Expanded coverage of pharmacogenetics Expanded coverage of drug transporters and their role in interactions Inclusion of new material on enzyme induction mechanisms in chapters on drug metabolism and drug interactions A new chapter on drug discovery that focuses on oncologic agents Inclusion of therapeutic antibodies in chapter on biotechnology products

Principles of Clinical Pharmacology

Principles of Clinical Pharmacology
Author: Arthur J. Atkinson
Publsiher: Academic Press
Total Pages: 626
Release: 2012
ISBN 10: 0123854717
ISBN 13: 9780123854711
Language: EN, FR, DE, ES & NL

Principles of Clinical Pharmacology Book Review:

Principles of Clinical Pharmacology is a successful survey covering the pharmacologic principles underlying the individualization of patient therapy and contemporary drug development. This essential reference continues to focus on the basics of clinical pharmacology for the development, evaluation, and clinical use of pharmaceutical products while also addressing the most recent advances in the field. Written by leading experts in academia, industry, clinical and regulatory settings, the third edition has been thoroughly updated to provide readers with an ideal reference covering the wide range of important topics impacting clinical pharmacology as the discipline plays an increasingly significant role in drug development and regulatory science. * Includes new chapters on imaging and the pharmacogenetic basis of adverse drug reactions. * Offers an expanded regulatory section that addresses US and international issues and guidelines. * Provides extended coverage of earlier chapters on transporters, pharmacogenetics and biomarkers and also illustrates the impact of gender on drug response. * Presents a broadened discussion of clinical trials from Phase 1 to incorporate Phases II and III.

Good Research Practice in Non Clinical Pharmacology and Biomedicine

Good Research Practice in Non Clinical Pharmacology and Biomedicine
Author: Anton Bespalov,Martin C. Michel,Thomas Steckler
Publsiher: Springer Nature
Total Pages: 424
Release: 2020-01-01
ISBN 10: 3030336565
ISBN 13: 9783030336561
Language: EN, FR, DE, ES & NL

Good Research Practice in Non Clinical Pharmacology and Biomedicine Book Review:

This open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.

Principles and Practice of Clinical Research

Principles and Practice of Clinical Research
Author: John I. Gallin,Frederick P Ognibene
Publsiher: Elsevier
Total Pages: 448
Release: 2011-04-28
ISBN 10: 9780080489568
ISBN 13: 0080489567
Language: EN, FR, DE, ES & NL

Principles and Practice of Clinical Research Book Review:

The second edition of this innovative work again provides a unique perspective on the clinical discovery process by providing input from experts within the NIH on the principles and practice of clinical research. Molecular medicine, genomics, and proteomics have opened vast opportunities for translation of basic science observations to the bedside through clinical research. As an introductory reference it gives clinical investigators in all fields an awareness of the tools required to ensure research protocols are well designed and comply with the rigorous regulatory requirements necessary to maximize the safety of research subjects. Complete with sections on the history of clinical research and ethics, copious figures and charts, and sample documents it serves as an excellent companion text for any course on clinical research and as a must-have reference for seasoned researchers. *Incorporates new chapters on Managing Conflicts of Interest in Human Subjects Research, Clinical Research from the Patient's Perspective, The Clinical Researcher and the Media, Data Management in Clinical Research, Evaluation of a Protocol Budget, Clinical Research from the Industry Perspective, and Genetics in Clinical Research *Addresses the vast opportunities for translation of basic science observations to the bedside through clinical research *Delves into data management and addresses how to collect data and use it for discovery *Contains valuable, up-to-date information on how to obtain funding from the federal government

Pharmacology and Therapeutics

Pharmacology and Therapeutics
Author: Scott A. Waldman,Andre Terzic
Publsiher: Saunders
Total Pages: 1378
Release: 2009
ISBN 10: 9781416060987
ISBN 13: 1416060987
Language: EN, FR, DE, ES & NL

Pharmacology and Therapeutics Book Review:

Everything you need to know about all of today's drugs in a coherent, easy-to-use format - from the underlying science through innovation, translation, regulation, and clinical implementation. This multimedia resource fills a critical need for a more clinically focused, user-friendly pharmacology reference. Evidence-based therapeutic guidelines facilitate decision making; and coverage of pharmacogenetics and pharmacogenomics, regenerative pharmacology, stem cell therapies, and the emerging field of individualized medicine keeps you at the forefront of the latest developments.

Medicine for MRCP

Medicine for MRCP
Author: Rupa Bessant,Jonathan Birns,Charlotte Ford
Publsiher: Oxford University Press
Total Pages: 936
Release: 2020-08-17
ISBN 10: 0191084948
ISBN 13: 9780191084942
Language: EN, FR, DE, ES & NL

Medicine for MRCP Book Review:

Medicine for MRCP provides a comprehensive review of the material that you need to pass the MRCP Parts 1 and 2 written papers. The twenty-seven chapters mapped out to the RCP syllabus, cover all areas from molecular medicine and genetics, through to medical law and ethics. Written by specialist contributors and educational experts, the content is carefully crafted to build your understanding for both papers. Each chapter begins with the basic science required for Part 1, before covering clinical medicine for Part 1, Part 2 and the PACES examinations. To ensure effective revision, material is presented in short sections with bullet lists, tables, and boxes. Over 150 drawings and photos illustrate key principles and clinical topics making them easier to retain. References to evidence-based protocols and directions to further reading allow for deeper understanding. Candidates can review their progress via the 180 end-of chapter self-assessment questions. Drawing on the authors' expertise, Medicine for MRCP is the ideal companion for the MRCP as well as a useful reference guide for practicing medical doctors.

Anesthetic Pharmacology

Anesthetic Pharmacology
Author: Alex S. Evers,Mervyn Maze,Evan D. Kharasch
Publsiher: Cambridge University Press
Total Pages: 135
Release: 2011-03-10
ISBN 10: 1139497022
ISBN 13: 9781139497022
Language: EN, FR, DE, ES & NL

Anesthetic Pharmacology Book Review:

In recent years our understanding of molecular mechanisms of drug action and interindividual variability in drug response has grown enormously. Meanwhile, the practice of anesthesiology has expanded to the preoperative environment and numerous locations outside the OR. Anesthetic Pharmacology: Basic Principles and Clinical Practice, 2nd edition, is an outstanding therapeutic resource in anesthesia and critical care: Section 1 introduces the principles of drug action, Section 2 presents the molecular, cellular and integrated physiology of the target organ/functional system and Section 3 reviews the pharmacology and toxicology of anesthetic drugs. The new Section 4, Therapeutics of Clinical Practice, provides integrated and comparative pharmacology and the practical application of drugs in daily clinical practice. Edited by three highly acclaimed academic anesthetic pharmacologists, with contributions from an international team of experts, and illustrated in full colour, this is a sophisticated, user-friendly resource for all practitioners providing care in the perioperative period.

Metabolic Regulation

Metabolic Regulation
Author: Keith N. Frayn
Publsiher: John Wiley & Sons
Total Pages: 384
Release: 2013-03-18
ISBN 10: 1118685334
ISBN 13: 9781118685334
Language: EN, FR, DE, ES & NL

Metabolic Regulation Book Review:

The important Third Edition of this successful book conveys a modern and integrated picture of metabolism and metabolic regulation. Explaining difficult concepts with unequalled clarity, author Keith Frayn provides the reader with an essential guide to the subject. Covering topics such as energy balance, body weight regulation and how the body copes with extreme situations, this book illustrates how metabolic regulation allows the human body to adapt to many different conditions. Changes throughout the new edition include: Extensive chapter updates Clear and accessible 2-color diagrams Q&A sections online at www.wiley.com/go/frayn to facilitate learning Frayn has written a book which will continue to be an extremely valuable tool for scientists, practitioners and students working and studying across a broad range of allied health sciences including medicine, biochemistry, nutrition, dietetics, sports science and nursing.

Benzodiazepines

Benzodiazepines
Author: John Peppin
Publsiher: Oxford University Press
Total Pages: 256
Release: 2020-10-01
ISBN 10: 0197517285
ISBN 13: 9780197517284
Language: EN, FR, DE, ES & NL

Benzodiazepines Book Review:

Developed decades ago to treat a legitimate medical need, benzodiazepines promisingly displaced less-effective and less-safe drugs, though prescribing has since exceeded their intended use and outpaced the available data. The current situation is characterized by excessive prescribing and extended utilization beyond good therapeutic practice. Evidence indicates that prolonged use of benzodiazepines causes a wide range of adverse reactions, and withdrawal can be particularly challenging. Misused, abused, diverted, and counterfeited, benzodiazepines have serious potential for substance use disorder, and are among the leading causes of drug-related overdose deaths. The Benzodiazepines Crisis sounds the alarm against the overuse of benzodiazepines, presenting an updated, evidence-based overview of this class of drugs and their negative consequences. Bringing together years of research, clinical expertise, and scientific evidence, this book aims to address a perceived lag between evidence and action in order to call for rational and dramatically reduced usage of benzodiazepines.

Practical Psychopharmacology

Practical Psychopharmacology
Author: Joseph Goldberg,Stephen Stahl
Publsiher: Cambridge University Press
Total Pages: 610
Release: 2021-04-29
ISBN 10: 1108450741
ISBN 13: 9781108450744
Language: EN, FR, DE, ES & NL

Practical Psychopharmacology Book Review:

A practical guide translating clinical trials findings, across major psychiatric disorders, to devise tailored, evidence-based treatments.

Geriatric Pharmacology

Geriatric Pharmacology
Author: Steven Atkinson
Publsiher: Unknown
Total Pages: 135
Release: 2016-11-01
ISBN 10: 9781683730088
ISBN 13: 1683730089
Language: EN, FR, DE, ES & NL

Geriatric Pharmacology Book Review:

Now in its second edition, Geriatric Pharmacology: The Principles of Practice & Clinical Recommendations is the optimal guide for anyone seeking straightforward, concise and user-friendly information on medication dynamics for older adults. Fully revised and updated, this invaluable resource has become the go-to favorite for healthcare professionals. Here's what you'll find: Learn to manage medication combinations without causing harm How to safely prescribe opioids Avoiding the top 10 most dangerous geriatric drugs Practical guidelines to stop and start prescriptions Drug-drug interaction charts and strategies

The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder

The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder
Author: American Psychiatric Association
Publsiher: American Psychiatric Pub
Total Pages: 224
Release: 2018-01-11
ISBN 10: 0890426821
ISBN 13: 9780890426821
Language: EN, FR, DE, ES & NL

The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder Book Review:

Alcohol use disorder (AUD) is a major public health problem in the United States. The estimated 12-month and lifetime prevalence values for AUD are 13.9% and 29.1%, respectively, with approximately half of individuals with lifetime AUD having a severe disorder. AUD and its sequelae also account for significant excess mortality and cost the United States more than $200 billion annually. Despite its high prevalence and numerous negative consequences, AUD remains undertreated. In fact, fewer than 1 in 10 individuals in the United States with a 12-month diagnosis of AUD receive any treatment. Nevertheless, effective and evidence-based interventions are available, and treatment is associated with reductions in the risk of relapse and AUD-associated mortality. The American Psychiatric Association Practice Guideline for the Pharmacological Treatment of Patients With Alcohol Use Disorder seeks to reduce these substantial psychosocial and public health consequences of AUD for millions of affected individuals. The guideline focuses specifically on evidence-based pharmacological treatments for AUD in outpatient settings and includes additional information on assessment and treatment planning, which are an integral part of using pharmacotherapy to treat AUD. In addition to reviewing the available evidence on the use of AUD pharmacotherapy, the guideline offers clear, concise, and actionable recommendation statements, each of which is given a rating that reflects the level of confidence that potential benefits of an intervention outweigh potential harms. The guideline provides guidance on implementing these recommendations into clinical practice, with the goal of improving quality of care and treatment outcomes of AUD.

Smith and Aitkenhead s Textbook of Anaesthesia E Book

Smith and Aitkenhead s Textbook of Anaesthesia E Book
Author: Alan R. Aitkenhead,Jonathan Thompson,David J. Rowbotham,Iain Moppett
Publsiher: Elsevier Health Sciences
Total Pages: 868
Release: 2013-08-08
ISBN 10: 0702051128
ISBN 13: 9780702051128
Language: EN, FR, DE, ES & NL

Smith and Aitkenhead s Textbook of Anaesthesia E Book Book Review:

Textbook of Anaesthesia has become the book of choice for trainee anaesthetists beginning their career in the specialty. It is highly suitable for part 1 of the Fellowship of the Royal College of Anaesthetists and similar examinations. It is also a practical guide for all anaesthetists and other health care professionals involved in the perioperative period.

Assisting at Surgical Operations

Assisting at Surgical Operations
Author: Comus Whalan
Publsiher: Cambridge University Press
Total Pages: 135
Release: 2006-08-17
ISBN 10: 1139457446
ISBN 13: 9781139457446
Language: EN, FR, DE, ES & NL

Assisting at Surgical Operations Book Review:

There are many superb books on how to do operations but there are few or none on how to assist at them, and none written either by or for medical students or doctors. Therefore, the skills that make an expert surgical assistant are difficult to acquire. Normally, they can only be learnt in a haphazard way, by spending years in the operating theatre. This book describes those skills in a concise and systematic way, in surgery in general, and in ten different speciality areas. Although intended mainly for clinical-level medical students and junior doctors, other people who assist at surgical operations, including general practitioners, nurse assistants and surgical technologists, will also find it useful. Whether planning a career in surgery, or simply aiming for high marks in a surgical rotation, there are few better ways to impress a surgeon than by skilfully assisting at surgical operations.

Oxford Textbook of Vasculitis

Oxford Textbook of Vasculitis
Author: Gene V. Ball,Barri J. Fessler,S. Louis Bridges
Publsiher: Oxford University Press, USA
Total Pages: 672
Release: 2014
ISBN 10: 0199659869
ISBN 13: 9780199659869
Language: EN, FR, DE, ES & NL

Oxford Textbook of Vasculitis Book Review:

A comprehensive review of inflammatory syndromes and diseases that affect the blood vessels, this volume draws upon authors from all over the world to present informed discussions on all types of vasculitis and related conditions.

Simulation for Designing Clinical Trials

Simulation for Designing Clinical Trials
Author: Hui Kimko,Stephen B. Duffull
Publsiher: CRC Press
Total Pages: 424
Release: 2002-12-12
ISBN 10: 0203910273
ISBN 13: 9780203910276
Language: EN, FR, DE, ES & NL

Simulation for Designing Clinical Trials Book Review:

Providing more than just a comprehensive history, critical vocabulary, insightful compilation of motivations, and clear explanation of the state-of-the-art of modern clinical trial simulation, this book supplies a rigorous framework for employing simulation as an experiment, according to a predefined simulation plan, that reflects good simulation p

Early Drug Development 2 Volume Set

Early Drug Development  2 Volume Set
Author: Fabrizio Giordanetto
Publsiher: John Wiley & Sons
Total Pages: 816
Release: 2018-12-10
ISBN 10: 3527341498
ISBN 13: 9783527341498
Language: EN, FR, DE, ES & NL

Early Drug Development 2 Volume Set Book Review:

This one-stop reference systematically covers key aspects in early drug development that are directly relevant to the discovery phase and are required for first-in-human studies. Its broad scope brings together critical knowledge from many disciplines, ranging from process technology to pharmacology to intellectual property issues. After introducing the overall early development workflow, the critical steps of early drug development are described in a sequential and enabling order: the availability of the drug substance and that of the drug product, the prediction of pharmacokinetics and -dynamics, as well as that of drug safety. The final section focuses on intellectual property aspects during early clinical development. The emphasis throughout is on recent case studies to exemplify salient points, resulting in an abundance of practice-oriented information that is usually not available from other sources. Aimed at medicinal chemists in industry as well as academia, this invaluable reference enables readers to understand and navigate the challenges in developing clinical candidate molecules that can be successfully used in phase one clinical trials.

Point of Care Ultrasound for Emergency Medicine and Resuscitation

Point of Care Ultrasound for Emergency Medicine and Resuscitation
Author: Paul Atkinson,Justin Bowra,David Lewis,Tim Harris
Publsiher: Oxford Clinical Imaging Guides
Total Pages: 264
Release: 2019-05-09
ISBN 10: 9780198777540
ISBN 13: 019877754X
Language: EN, FR, DE, ES & NL

Point of Care Ultrasound for Emergency Medicine and Resuscitation Book Review:

The Oxford Clinical Imaging Guides are specifically designed to help doctors master imaging techniques. Each guide explains the principles and practice of using imaging in an easy-to-read, highly-illustrated, and authoritative manner. Point of Care Ultrasound for Emergency Medicine and Resuscitation is the definitive guide to using this indispensable clinical tool quickly, safely, and accurately to diagnose patients in emergency, acute, and critical care settings. With a practical focus on how to perform ultrasound and interpret images, this book demonstrates how the reader can use ultrasound safely in patient management to diagnose and manage shock, acute presentations, or the acute phases of key conditions. Extensively illustrated, this resource also comes with online access to 160 ultrasound clips and over 130 annotated ultrasound images. Written by expert educators, this book is mapped to the curriculum for the International Federation for Emergency Medicine to teach emergency and acute medics exactly what they need to know. This guide is highly relevant for the syllabi of Emergency Medicine colleges and associations in the USA, Canada, UK, Australasia and South Africa.

Oxford Textbook of Palliative Medicine

Oxford Textbook of Palliative Medicine
Author: Nathan Cherny,Norman Levan Chair of Humanistic Medicine Associate Professor of Medicine (Bgu) and Director Cancer Pain and Palliative Medicine Service Nathan Cherny,Marie Fallon,St Columba's Hospice Chair of Palliative Medicine Marie Fallon,Stein Kaasa,Russell K. Portenoy,David C. Currow,Professor Discipline of Palliative and Supportive Services David C Currow
Publsiher: Oxford University Press, USA
Total Pages: 1280
Release: 2015-04-07
ISBN 10: 0199656096
ISBN 13: 9780199656097
Language: EN, FR, DE, ES & NL

Oxford Textbook of Palliative Medicine Book Review:

The definitive Oxford Textbook of Palliative Medicine, now in its fifth edition, has again been thoroughly updated to offer a truly global perspective in this field of extraordinary talent and thoughtfulness. Updated to include new sections devoted to assessment tools, care of patients with cancer, and the management of issues in the very young and the very old, this leading textbook covers all the new and emerging topics since its original publication in 1993. In addition, the multi-disciplinary natureof palliative care is emphasized throughout the book, covering areas from ethical and communication issues, the treatment of symptoms and the management of pain. The printed book is complemented with 12 months free access to the online version, which includes expanded chapter information and links from the references to primary research journal articles, ensuring this edition continues to be at the forefront of palliative medicine. This fifth edition of the Oxford Textbook of Palliative Medicine is dedicated to the memory of Professor Geoffrey Hanks, pioneer in the field of palliative medicine, and co-editor of the previous four editions. A truly comprehensive text, no hospital, hospice, palliative care service, or medicallibrary should be without this essential source of information.