Artificial Neural Network for Drug Design Delivery and Disposition

Artificial Neural Network for Drug Design  Delivery and Disposition
Author: Munish Puri,Yashwant Pathak,Vijay Kumar Sutariya,Srinivas Tipparaju,Wilfrido Moreno
Publsiher: Academic Press
Total Pages: 440
Release: 2015-10-15
ISBN 10: 0128017449
ISBN 13: 9780128017449
Language: EN, FR, DE, ES & NL

Artificial Neural Network for Drug Design Delivery and Disposition Book Review:

Artificial Neural Network for Drug Design, Delivery and Disposition provides an in-depth look at the use of artificial neural networks (ANN) in pharmaceutical research. With its ability to learn and self-correct in a highly complex environment, this predictive tool has tremendous potential to help researchers more effectively design, develop, and deliver successful drugs. This book illustrates how to use ANN methodologies and models with the intent to treat diseases like breast cancer, cardiac disease, and more. It contains the latest cutting-edge research, an analysis of the benefits of ANN, and relevant industry examples. As such, this book is an essential resource for academic and industry researchers across the pharmaceutical and biomedical sciences. Written by leading academic and industry scientists who have contributed significantly to the field and are at the forefront of artificial neural network (ANN) research Focuses on ANN in drug design, discovery and delivery, as well as adopted methodologies and their applications to the treatment of various diseases and disorders Chapters cover important topics across the pharmaceutical process, such as ANN in structure-based drug design and the application of ANN in modern drug discovery Presents the future potential of ANN-based strategies in biomedical image analysis and much more

3D Printing of Pharmaceuticals and Drug Delivery Devices

3D Printing of Pharmaceuticals and Drug Delivery Devices
Author: Dimitrios A. Lamprou
Publsiher: MDPI
Total Pages: 436
Release: 2020-07-01
ISBN 10: 3039364235
ISBN 13: 9783039364237
Language: EN, FR, DE, ES & NL

3D Printing of Pharmaceuticals and Drug Delivery Devices Book Review:

The 3D printing (3DP) process was patented in 1986; however, only in the last decade has it begun to be used for medical applications, as well as in the fields of prosthetics, bio-fabrication, and pharmaceutical printing. 3DP or additive manufacturing (AM) is a family of technologies that implement layer-by-layer processes in order to fabricate physical models based on a computer aided design (CAD) model. 3D printing permits the fabrication of high degrees of complexity with great reproducibility in a fast and cost-effective fashion. 3DP technology offers a new paradigm for the direct manufacture of individual dosage forms and has the potential to allow for variations in size and geometry as well as control dose and release behavior. Furthermore, the low cost and ease of use of 3DP systems means that the possibility of manufacturing medicines and medical devices at the point of dispensing or at the point of use could become a reality. 3DP thus offers the perfect innovative manufacturing route to address the critical capability gap that hinders the widespread exploitation of personalized medicines for molecules that are currently not easy to deliver. This Special Issue will address new developments in the area of 3D printing and bioprinting for drug delivery applications, covering the recent advantages and future directions of additive manufacturing for pharmaceutical products.

Polysaccharide Nanoparticles

Polysaccharide Nanoparticles
Author: Jayachandran Venkatesan,Se-Kwon Kim,Sukumaran Anil,Rekha P. D
Publsiher: Elsevier
Total Pages: 690
Release: 2022-01-11
ISBN 10: 0128223561
ISBN 13: 9780128223567
Language: EN, FR, DE, ES & NL

Polysaccharide Nanoparticles Book Review:

Polysaccharide Nanoparticles: Preparation and Biomedical Applications provides detailed information on polysaccharides nanoparticles in terms of their synthesis and applications. Naturally occurring polysaccharides are widely used as food materials, particularly in Asia. Different kinds of polysaccharide materials are available from nature with various resources such as crustaceans and algae. The exploration and exploitation of polysaccharides nanoparticles from natural resource is at the heart of this book, which also explores the synthesis, preparation and applications of polysaccharides nanoparticles for tissue engineering and food applications. This is an important reference for materials scientists and bioengineers who are looking to gain a greater understanding on how polysaccharides nanoparticles are being used for a variety of biomedical applications. Explains the major synthesis and preparation methods of polysaccharide-based nanoparticles Demonstrates how polysaccharides nanoparticles are being used for a range of biomedical applications, including tissue engineering, drug delivery and biosensors Assesses the major challenges and risks of using polysaccharides nanoparticles safely and effectively

Digitization of Healthcare Data using Blockchain

Digitization of Healthcare Data using Blockchain
Author: T. Poongodi,D. Sumathi,B. Balamurugan,K. S. Savita
Publsiher: John Wiley & Sons
Total Pages: 320
Release: 2022-07-06
ISBN 10: 1119792711
ISBN 13: 9781119792710
Language: EN, FR, DE, ES & NL

Digitization of Healthcare Data using Blockchain Book Review:

DIGITIZATION OF HEALTHCARE DATA USING BLOCKCHAIN The book gives a detailed description of the integration of blockchain technology for Electronic Health Records and provides the research challenges to consider in various disciplines such as supply chain, drug discovery, and data management. The aim of the book is to investigate the concepts of blockchain technology and its association with the recent development and advancements in the medical field. Moreover, it focuses on the integration of workflow strategies like NLP, and AI which could be adopted for boosting the clinical documentation and electronic healthcare records (EHR) usage by bringing down the physician EHR data entry. Also, the book covers the usage of smart contracts for securing patient records. Digitization of Healthcare Data Using Blockchain presents the practical implementations that deal with developing a web framework for building highly usable healthcare applications, a simple blockchain-powered EHR system. Audience Researchers in information technology, artificial intelligence, electronics engineering, medical informatics, as well as policymakers and healthcare providers and management systems.

Machine Learning and Analytics in Healthcare Systems

Machine Learning and Analytics in Healthcare Systems
Author: Himani Bansal,Balamurugan Balusamy,T. Poongodi,Firoz Khan KP
Publsiher: CRC Press
Total Pages: 274
Release: 2021-07-01
ISBN 10: 1000406199
ISBN 13: 9781000406191
Language: EN, FR, DE, ES & NL

Machine Learning and Analytics in Healthcare Systems Book Review:

This book provides applications of machine learning in healthcare systems and seeks to close the gap between engineering and medicine. It will combine the design and problem-solving skills of engineering with health sciences, in order to advance healthcare treatment. The book will include areas such as diagnosis, monitoring, and therapy. The book will provide real-world case studies, gives a detailed exploration of applications in healthcare systems, offers multiple perspectives on a variety of disciplines, while also letting the reader know how to avoid some of the consequences of old methods with data sharing. The book can be used as a reference for practitioners, researchers and for students at basic and intermediary levels in Computer Science, Electronics and Communications.

In Silico Drug Design

In Silico Drug Design
Author: Kunal Roy
Publsiher: Academic Press
Total Pages: 886
Release: 2019-02-12
ISBN 10: 0128163771
ISBN 13: 9780128163771
Language: EN, FR, DE, ES & NL

In Silico Drug Design Book Review:

In Silico Drug Design: Repurposing Techniques and Methodologies explores the application of computational tools that can be utilized for this approach. The book covers theoretical background and methodologies of chem-bioinformatic techniques and network modeling and discusses the various applied strategies to systematically retrieve, integrate and analyze datasets from diverse sources. Other topics include in silico drug design methods, computational workflows for drug repurposing, and network-based in silico screening for drug efficacy. With contributions from experts in the field and the inclusion of practical case studies, this book gives scientists, researchers and R&D professionals in the pharmaceutical industry valuable insights into drug design. Discusses the theoretical background and methodologies of useful techniques of cheminformatics and bioinformatics that can be applied for drug repurposing Offers case studies relating to the in silico modeling of FDA-approved drugs for the discovery of antifungal, anticancer, antiplatelet agents, and for drug therapies against diseases Covers tools and databases that can be utilized to facilitate in silico methods for drug repurposing

Artificial Intelligence in Healthcare

Artificial Intelligence in Healthcare
Author: Adam Bohr,Kaveh Memarzadeh
Publsiher: Academic Press
Total Pages: 378
Release: 2020-06-21
ISBN 10: 0128184396
ISBN 13: 9780128184394
Language: EN, FR, DE, ES & NL

Artificial Intelligence in Healthcare Book Review:

Artificial Intelligence (AI) in Healthcare is more than a comprehensive introduction to artificial intelligence as a tool in the generation and analysis of healthcare data. The book is split into two sections where the first section describes the current healthcare challenges and the rise of AI in this arena. The ten following chapters are written by specialists in each area, covering the whole healthcare ecosystem. First, the AI applications in drug design and drug development are presented followed by its applications in the field of cancer diagnostics, treatment and medical imaging. Subsequently, the application of AI in medical devices and surgery are covered as well as remote patient monitoring. Finally, the book dives into the topics of security, privacy, information sharing, health insurances and legal aspects of AI in healthcare. Highlights different data techniques in healthcare data analysis, including machine learning and data mining Illustrates different applications and challenges across the design, implementation and management of intelligent systems and healthcare data networks Includes applications and case studies across all areas of AI in healthcare data

Pharmacokinetics and Toxicokinetic Considerations Vol II

Pharmacokinetics and Toxicokinetic Considerations   Vol II
Author: Rakesh Kumar Tekade
Publsiher: Academic Press
Total Pages: 814
Release: 2022-02-17
ISBN 10: 0323913164
ISBN 13: 9780323913164
Language: EN, FR, DE, ES & NL

Pharmacokinetics and Toxicokinetic Considerations Vol II Book Review:

Pharmacokinetics and Toxicokinetic Considerations explains the central principles, cutting-edge methodologies, and incipient thought processes applied to toxicology research. As part of the Advances in Pharmaceutical Product Development and Research series, the book provides expert literature on dose, dosage regimen and dose adjustment, medication errors, and approaches for its prevention, the concept of pharmacotherapy, and managed care in clinical interventions. It expounds on strategies to revamp the pharmacokinetics of the drug and the factors affecting the stability of drugs and their metabolites in biological matrices. Finally, the book offers focused elaborations on various bioanalytical methods for bioavailability and bioequivalence assessment and integrates the wide-ranging principles and concepts shared by toxicokinetics and pharmacodynamics as mutual crosstalk rather than isolated observations. It will be helpful to researchers and advanced students working in the pharmaceutical, cosmetics, biotechnology, food, and related industries including toxicologists, pharmacists, and pharmacologists. Allows readers to systematically integrate up-to-date research findings into their laboratory work Presents focused explorations of bioanalytical methods for bioavailability and bioequivalence assessment Provides clinical applications of concepts

Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery

Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery
Author: Amit Kumar Nayak,Md Saquib Hasnain,Dilipkumar Pal
Publsiher: Springer Nature
Total Pages: 185
Release: 2021-07-05
ISBN 10: 981162271X
ISBN 13: 9789811622717
Language: EN, FR, DE, ES & NL

Ionically Gelled Biopolysaccharide Based Systems in Drug Delivery Book Review:

This volume provides a thorough insight into the chemistry and mechanism of ionic gelations of various ionic biopolysaccharides, like alginate, gellan gum, pectin, chitosan, carboxymethyl cellulose, etc., and the applications of various ionically gelled biopolysaccharides in drug delivery fields, with chapters emphasizing the recent advances in the field by the experts. This book will be of interest to graduate students and academic and industry researchers from pharmacy, biotechnology, bioengineering, biomedical and material sciences fields.

Translational Biotechnology

Translational Biotechnology
Author: Yasha Hasija
Publsiher: Academic Press
Total Pages: 452
Release: 2021-01-17
ISBN 10: 0128219734
ISBN 13: 9780128219737
Language: EN, FR, DE, ES & NL

Translational Biotechnology Book Review:

Translational Biotechnology: A Journey from Laboratory to Clinics presents an integrative and multidisciplinary approach to biotechnology to help readers bridge the gaps between fundamental and functional research. The book provides state-of-the-art and integrative views of translational biotechnology by covering topics from basic concepts to novel methodologies. Topics discussed include biotechnology-based therapeutics, pathway and target discovery, biological therapeutic modalities, translational bioinformatics, and system and synthetic biology. Additional sections cover drug discovery, precision medicine and the socioeconomic impact of translational biotechnology. This book is valuable for bioinformaticians, biotechnologists, and members of the biomedical field who are interested in learning more about this promising field. Explains biotechnology in a different light by using an application-oriented approach Discusses practical approaches in the development of precision medicine tools, systems and dynamical medicine approaches Promotes research in the field of biotechnology that is translational in nature, cost-effective and readily available to the community

Pharmaceutical Drug Product Development and Process Optimization

Pharmaceutical Drug Product Development and Process Optimization
Author: Sarwar Beg,Majed Al Robaian,Mahfoozur Rahman,Syed Sarim Imam,Nabil Alruwaili,Sunil Kumar Panda
Publsiher: CRC Press
Total Pages: 382
Release: 2020-05-01
ISBN 10: 1000731588
ISBN 13: 9781000731583
Language: EN, FR, DE, ES & NL

Pharmaceutical Drug Product Development and Process Optimization Book Review:

Pharmaceutical manufacturers are constantly facing quality crises of drug products, leading to an escalating number of product recalls and rejects. Due to the involvement of multiple factors, the goal of achieving consistent product quality is always a great challenge for pharmaceutical scientists. This volume addresses this challenge by using the Quality by Design (QbD) concept, which was instituted to focus on the systematic development of drug products with predefined objectives to provide enhanced product and process understanding. This volume presents and discusses the vital precepts underlying the efficient, effective, and cost effective development of pharmaceutical drug products. It focuses on the adoption of systematic quality principles of pharmaceutical development, which is imperative in achieving continuous improvement in end-product quality and also leads to reducing cost, time, and effort, while meeting regulatory requirements. The volume covers the important new advances in the development of solid oral dosage forms, modified release oral dosage forms, parenteral dosage forms, semisolid dosage forms, transdermal drug, delivery systems, inhalational dosage forms, ocular drug delivery systems, nanopharmaceutical products, and nanoparticles for oral delivery.

ECPPM 2021 eWork and eBusiness in Architecture Engineering and Construction

ECPPM 2021   eWork and eBusiness in Architecture  Engineering and Construction
Author: Vitaly Semenov,Raimar J Scherer
Publsiher: CRC Press
Total Pages: 596
Release: 2021-07-25
ISBN 10: 1000413322
ISBN 13: 9781000413328
Language: EN, FR, DE, ES & NL

ECPPM 2021 eWork and eBusiness in Architecture Engineering and Construction Book Review:

eWork and eBusiness in Architecture, Engineering and Construction 2021 collects the papers presented at the 13th European Conference on Product and Process Modelling (ECPPM 2021, Moscow, 5-7 May 2021). The contributions cover a wide spectrum of thematic areas that hold great promise towards the advancement of research and technological development targeted at the digitalization of the AEC/FM (Architecture, Engineering, Construction and Facilities Management) domains. High quality contributions are devoted to critically important problems that arise, including: Information and Knowledge Management Semantic Web and Linked Data Communication and Collaboration Technologies Software Interoperability BIM Servers and Product Lifecycle Management Systems Digital Twins and Cyber-Physical Systems Sensors and Internet of Things Big Data Artificial and Augmented Intelligence in AEC Construction Management 5D/nD Modelling and Planning Building Performance Simulation Contract, Cost and Risk Management Safety and Quality Sustainable Buildings and Urban Environments Smart Buildings and Cities BIM Standardization, Implementation and Adoption Regulatory and Legal Aspects BIM Education and Training Industrialized Production, Smart Products and Services Over the past quarter century, the biennial ECPPM conference series, as the oldest BIM conference, has provided researchers and practitioners with a unique platform to present and discuss the latest developments regarding emerging BIM technologies and complementary issues for their adoption in the AEC/FM industry.

Improving Animal Welfare

Improving Animal Welfare
Author: Temple Grandin
Publsiher: CABI
Total Pages: 441
Release: 2020-12-08
ISBN 10: 1789245214
ISBN 13: 9781789245219
Language: EN, FR, DE, ES & NL

Improving Animal Welfare Book Review:

Completely revised, updated and with four new chapters on sustainability, new technologies, precision agriculture and the future of animal welfare. This book is edited by an outstanding world expert on animal welfare, it emphasizes throughout the importance of measuring conditions that compromise welfare, such as lameness, heat stress, body condition, and bruises during transport.The book combines scientific information with practical recommendations for use on commercial operations and reviews practical information on livestock handling, euthanasia, slaughter, pain relief, and assessments of abnormal behavior.

COVID 19 Pandemic

COVID 19 Pandemic
Author: Mamata Mohapatra,Balamati Choudhury,Suddhasatwa Basu
Publsiher: Springer Nature
Total Pages: 135
Release: 2022
ISBN 10: 9811643725
ISBN 13: 9789811643729
Language: EN, FR, DE, ES & NL

COVID 19 Pandemic Book Review:

This book provides a comprehensive overview of recent novel coronavirus (SARS-CoV-2) infection and discusses developments in the field of nanoparticle/inorganic/organic materials development for antiviral application, therapeutic applications, PPE kit formulations and inclusion of simulated data. The contents focus on measures to keep the infections in check, materials aspects for detection and monitoring, AI modeling for prediction of spread of the virus, among others. This book will be a useful reference for researchers, scientists and policy makers alike.

Dosage Form Design Parameters

Dosage Form Design Parameters
Author: Anonim
Publsiher: Academic Press
Total Pages: 810
Release: 2018-07-25
ISBN 10: 012814422X
ISBN 13: 9780128144220
Language: EN, FR, DE, ES & NL

Dosage Form Design Parameters Book Review:

Dosage Form Design Parameters, Volume II, examines the history and current state of the field within the pharmaceutical sciences, presenting key developments. Content includes drug development issues, the scale up of formulations, regulatory issues, intellectual property, solid state properties and polymorphism. Written by experts in the field, this volume in the Advances in Pharmaceutical Product Development and Research series deepens our understanding of dosage form design parameters. Chapters delve into a particular aspect of this fundamental field, covering principles, methodologies and the technologies employed by pharmaceutical scientists. In addition, the book contains a comprehensive examination suitable for researchers and advanced students working in pharmaceuticals, cosmetics, biotechnology and related industries. Examines the history and recent developments in drug dosage forms for pharmaceutical sciences Focuses on physicochemical aspects, prefomulation solid state properties and polymorphism Contains extensive references for further discovery and learning that are appropriate for advanced undergraduates, graduate students and those interested in drug dosage design

Artificial intelligence for Drug Discovery and Development

Artificial intelligence for Drug Discovery and Development
Author: Jianfeng Pei,Alex Zhavoronkov
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-11-16
ISBN 10: 288971649X
ISBN 13: 9782889716494
Language: EN, FR, DE, ES & NL

Artificial intelligence for Drug Discovery and Development Book Review:

Topic editor Alex Zhavoronkov is the founder of Insilico Medicine, a company specializing in AI research. He is also a professor at the Buck Institute for Research on Aging. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Current Trends and Advances in Computer Aided Intelligent Environmental Data Engineering

Current Trends and Advances in Computer Aided Intelligent Environmental Data Engineering
Author: Goncalo Marques,Joshua O. Ighalo
Publsiher: Academic Press
Total Pages: 474
Release: 2022-03-20
ISBN 10: 0323855989
ISBN 13: 9780323855983
Language: EN, FR, DE, ES & NL

Current Trends and Advances in Computer Aided Intelligent Environmental Data Engineering Book Review:

Current Trends and Advances in Computer-Aided Intelligent Environmental Data Engineering merges computer engineering and environmental engineering. The book presents the latest finding on how data science and AI-based tools are being applied in environmental engineering research. This application involves multiple domains such as data science and artificial intelligence to transform the data collected by intelligent sensors into relevant and reliable information to support decision-making. These tools include fuzzy logic, knowledge-based systems, particle swarm optimization, genetic algorithms, Monte Carlo simulation, artificial neural networks, support vector machine, boosted regression tree, simulated annealing, ant colony algorithm, decision tree, immune algorithm, and imperialist competitive algorithm. This book is a fundamental information source because it is the first book to present the foundational reference material in this new research field. Furthermore, it gives a critical overview of the latest cross-domain research findings and technological developments on the recent advances in computer-aided intelligent environmental data engineering. Captures the application of data science and artificial intelligence for a broader spectrum of environmental engineering problems Presents methods and procedures as well as case studies where state-of-the-art technologies are applied in actual environmental scenarios Offers a compilation of essential and critical reviews on the application of data science and artificial intelligence to the entire spectrum of environmental engineering

Global Supply Chains in the Pharmaceutical Industry

Global Supply Chains in the Pharmaceutical Industry
Author: Nozari, Hamed,Szmelter, Agnieszka
Publsiher: IGI Global
Total Pages: 373
Release: 2018-11-09
ISBN 10: 1522559221
ISBN 13: 9781522559221
Language: EN, FR, DE, ES & NL

Global Supply Chains in the Pharmaceutical Industry Book Review:

In a rapidly growing global economy, where there is a constant emergence of new business models and dynamic changes to the business ecosystem, there is a need for the integration of traditional, new, and hybrid concepts in the complex structure of supply chain management. Within the fast-paced pharmaceutical industry, product strategy, life cycles, and distribution must maintain the highest level of agility. Therefore, organizations need strong supply chain capabilities to profitably compete in the marketplace. Global Supply Chains in the Pharmaceutical Industry provides innovative insights into the efforts needed to build and maintain a strong supply chain network in order to achieve efficient fulfillment of demand, drive outstanding customer value, enhance organizational responsiveness, and build network resiliency. This publication is designed for supply chain managers, policymakers, researchers, academicians, and students, and covers topics centered on economic cycles, sustainable development, and new forces in the global economy.

Multivariate Analysis in the Pharmaceutical Industry

Multivariate Analysis in the Pharmaceutical Industry
Author: Ana Patricia Ferreira,Jose C. Menezes,Mike Tobyn
Publsiher: Academic Press
Total Pages: 464
Release: 2018-04-24
ISBN 10: 012811066X
ISBN 13: 9780128110669
Language: EN, FR, DE, ES & NL

Multivariate Analysis in the Pharmaceutical Industry Book Review:

Multivariate Analysis in the Pharmaceutical Industry provides industry practitioners with guidance on multivariate data methods and their applications over the lifecycle of a pharmaceutical product, from process development, to routine manufacturing, focusing on the challenges specific to each step. It includes an overview of regulatory guidance specific to the use of these methods, along with perspectives on the applications of these methods that allow for testing, monitoring and controlling products and processes. The book seeks to put multivariate analysis into a pharmaceutical context for the benefit of pharmaceutical practitioners, potential practitioners, managers and regulators. Users will find a resources that addresses an unmet need on how pharmaceutical industry professionals can extract value from data that is routinely collected on products and processes, especially as these techniques become more widely used, and ultimately, expected by regulators. Targets pharmaceutical industry practitioners and regulatory staff by addressing industry specific challenges Includes case studies from different pharmaceutical companies and across product lifecycle of to introduce readers to the breadth of applications Contains information on the current regulatory framework which will shape how multivariate analysis (MVA) is used in years to come

Neurodevelopment and Intelligence Impacts of Nutrition Environmental Toxins and Stress Volumes 1 and 2

Neurodevelopment and Intelligence  Impacts of Nutrition  Environmental Toxins  and Stress  Volumes 1 and 2
Author: Charles A. Lewis, MD MPH
Publsiher: Psy Press
Total Pages: 810
Release: 2022-03-01
ISBN 10: 1928374650XXX
ISBN 13: 9182736450XXX
Language: EN, FR, DE, ES & NL

Neurodevelopment and Intelligence Impacts of Nutrition Environmental Toxins and Stress Volumes 1 and 2 Book Review:

This special edition of Neurodevelopment and Intelligence contains both Volumes One and Two. The set provides an understanding neurodevelopmental risks during fetal and early life, and of the things that can go awry that limit or hinder healthy brain development, leading to a loss of intellectual abilities or causing disabilities such as autism spectrum disorder. It should be of interest to anyone interested in brain health, preventive medicine, pediatrics, public health policy, present and prospective parents, and those planning on pregnancy and parturition. Herein, Dr. Lewis explains: How people got smarter for more than a century and and why the alternative title of the book is Swimming in a Poisoned Pond —The Looming Demise of Cognitive and Mental Health in America How any healthy child can be a genius with advanced planning All the nasty things in your home that cause brain damage The disgusting things in your water that harm the brain The prenatal vitamins that prevent autism How ADHD is a lifestyle disease The eight pillars of health and their effects on the brain What men can do to sire smarter children The environmental toxins that cause violent crime and suicide How to make your home safe for your child’s brain The role of gut bacteria on the brain How to make pregnancy safer for the fetal brain Foods that improve brain function Maternal life style factors that affect IQ The seven pillars of health and their effects on the brain What men can do to sire smarter children How to make your home safe for your child’s brain The role of gut bacteria on the brain The disruptive effects of sleep deprivation and sleep disordered breathing on brain development, and sleep hygiene for children The effects of stress on the brain and its functioning The harmful effects of poverty on the brain How noise and noise pollution harm brain development. How good public policy can give us a brighter future Foods that improve brain function and make us happy and engaged The effects of Exercise and Environmental Enrichment Kiss your genetic legacy goodbye! Why you will likely never be a grandparent if you don’t already have children How stress makes us stupid Why people are getting dumber even though we have better medical care and more access to education. Are we already too dumb to save ourselves from our mistakes? How psychopathic corporations, stupidity, and structural racism raid America’s wealth The book is a serious scientific exploration of neurodevelopment on which policy and personal behavior changes can be based to improve health, happiness, and intellectual curiosity. Section I section lays out an description of the Intelligence Quotient (IQ) and why it can used as a proxy for neurodevelopment. It explains IQ tests and other developmental scales scoring, and some of their limitations. The high metabolic cost of a large brain and the survival advantage provided by epigenetic adaptation to downsize the brain to the current environmental conditions is described, explaining why a less costly and less intelligent brain are adaptive to leaner times. An estimate is made for the average human IQ in full health and nutrition, (about two standard deviations above the current average, or an IQ of 130). A primer on inflammation is given. Section 2: discusses the impact of anemia and iron on brain development. Topics include: Hookworm, malaria, and infections. Most of this section discusses iron deficiency, iron supplementation in pregnancy and infancy, and the role other minerals and vitamins required for blood formation Section 3: Covers the role of iodine and thyroid hormone on neurodevelopment. The following chapters discuss thyroid hormone disruptors including fluoride and bromide, organohalogens, thyroid disrupting organic pollutants, organophosphates and other biocides, and foods and food additives that impact thyroid function Section 4 covers neurotoxic metals in the environment. The neurotoxic metals that most commonly impact brain health are discussed, including arsenic, lead, mercury, manganese. The impacts of cadmium and aluminum on fetal and infant health are reviewed. Toxic metal exposure during development most commonly occurs from water contamination, and Chapter 18 covers water filtration for removal of these toxins. Section 5 discusses the role of toxic metals, dietary factors, and the role of the intestinal microbiome on the causation and exacerbation of autism spectrum disorder. Evidence on the role of special diets for ASD is reviewed.The timing of the development of ASD is discussed; as it is essential to understanding which exposures are relevant and amenable to treatment. Section 6 discussed the generation of air pollution from combustion of fuels and the adverse impacts of it on brain health. Effects of Particulate matter (PM) on health, Alzheimer’s and Parkinson’s disease are reviewed, along with its effects on the premature birth of infants, neurodevelopment, IQ, and autism. Mitigation of risk is discussed. Section 7 outlines maternal factors that impact neurodevelopment and intelligence. The causes and effects of preterm birth and small for gestational age are explored, with a particular focus on environmental influences. Section 8 covers the effect of general health on neurodevelopment, including the impact of diet on the intestinal microbiome, exercise, sleep deprivation, sleep-disordered breathing, and explains the roll of lifestyle in ADHD. Section 9 discusses the effects of psychosocial stress on neurodevelopment and intellectual performance, and discusses the epigenetic effects of stress on brain development and behavior. The role of having a supportive social environment, a stimulating environment, and education on brain development, IQ an health are discussed. The effects of prenatal stress on the brain are reviewed. Other topics include the effect of stress and telomere length, the effects of poverty or domestic violence on IQ score, and the effects of stress on the hypothalamic-pituitary-adrenal axis and on the gut. The effects of noise on hearing, academic performance, and sleep are reviewed. The need to confront endemic stress as a societal norm is discussed.