Antibiotic Resistance

Antibiotic Resistance
Author: Kateryna Kon,Mahendra Rai
Publsiher: Academic Press
Total Pages: 436
Release: 2016-06-14
ISBN 10: 0128036680
ISBN 13: 9780128036686
Language: EN, FR, DE, ES & NL

Antibiotic Resistance Book Review:

Antibiotic Resistance: Mechanisms and New Antimicrobial Approaches discusses up-to-date knowledge in mechanisms of antibiotic resistance and all recent advances in fighting microbial resistance such as the applications of nanotechnology, plant products, bacteriophages, marine products, algae, insect-derived products, and other alternative methods that can be applied to fight bacterial infections. Understanding fundamental mechanisms of antibiotic resistance is a key step in the discovery of effective methods to cope with resistance. This book also discusses methods used to fight antibiotic-resistant infection based on a deep understanding of the mechanisms involved in the development of the resistance. Discusses methods used to fight antibiotic-resistant infection based on a deep understanding of mechanisms involved in the development of the resistance Provides information on modern methods used to fight antibiotic resistance Covers a wide range of alternative methods to fight bacterial resistance, offering the most complete information available Discusses both newly emerging trends and traditionally applied methods to fight antibiotic resistant infections in light of recent scientific developments Offers the most up-to-date information in fighting antibiotic resistance Includes involvement of contributors all across the world, presenting questions of interest to readers of both developed and developing countries

Antibiotic Drug Resistance

Antibiotic Drug Resistance
Author: José-Luis Capelo-Martínez,Gilberto Igrejas
Publsiher: John Wiley & Sons
Total Pages: 720
Release: 2019-09-24
ISBN 10: 1119282527
ISBN 13: 9781119282525
Language: EN, FR, DE, ES & NL

Antibiotic Drug Resistance Book Review:

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies

Antibiotics and Antibiotic Resistance

Antibiotics and Antibiotic Resistance
Author: Ola Sköld
Publsiher: John Wiley & Sons
Total Pages: 224
Release: 2011-10-07
ISBN 10: 1118075587
ISBN 13: 9781118075586
Language: EN, FR, DE, ES & NL

Antibiotics and Antibiotic Resistance Book Review:

This book, which is the translated version of a Swedish book, combines a general introduction of a variety of antibiotics with a more in-depth discussion of resistance. The focus on resistance in learning about antibiotics will help future scientists recognize the problem antibiotics resistance poses for medicinal and drug-related fields, and perhaps trigger more research and discoveries to fight antibiotic resistant strains. Current overviews of the topic are included, along with specific discussions on the individual mechanisms (betalactams, glycopeptides, aminoglycosides, etc) used in various antibacterial agents and explanations of how resistances to those develop. Methods for counteracting resistance development in bacteria are discussed as well.

Improving Food Safety Through a One Health Approach

Improving Food Safety Through a One Health Approach
Author: Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publsiher: National Academies Press
Total Pages: 418
Release: 2012-10-10
ISBN 10: 0309259339
ISBN 13: 9780309259330
Language: EN, FR, DE, ES & NL

Improving Food Safety Through a One Health Approach Book Review:

Globalization of the food supply has created conditions favorable for the emergence, reemergence, and spread of food-borne pathogens-compounding the challenge of anticipating, detecting, and effectively responding to food-borne threats to health. In the United States, food-borne agents affect 1 out of 6 individuals and cause approximately 48 million illnesses, 128,000 hospitalizations, and 3,000 deaths each year. This figure likely represents just the tip of the iceberg, because it fails to account for the broad array of food-borne illnesses or for their wide-ranging repercussions for consumers, government, and the food industry-both domestically and internationally. A One Health approach to food safety may hold the promise of harnessing and integrating the expertise and resources from across the spectrum of multiple health domains including the human and veterinary medical and plant pathology communities with those of the wildlife and aquatic health and ecology communities. The IOM's Forum on Microbial Threats hosted a public workshop on December 13 and 14, 2011 that examined issues critical to the protection of the nation's food supply. The workshop explored existing knowledge and unanswered questions on the nature and extent of food-borne threats to health. Participants discussed the globalization of the U.S. food supply and the burden of illness associated with foodborne threats to health; considered the spectrum of food-borne threats as well as illustrative case studies; reviewed existing research, policies, and practices to prevent and mitigate foodborne threats; and, identified opportunities to reduce future threats to the nation's food supply through the use of a "One Health" approach to food safety. Improving Food Safety Through a One Health Approach: Workshop Summary covers the events of the workshop and explains the recommendations for future related workshops.

Antibiotic Resistance

Antibiotic Resistance
Author: Institute of Medicine,Board on Global Health,Forum on Microbial Threats
Publsiher: National Academies Press
Total Pages: 496
Release: 2011-01-10
ISBN 10: 0309156114
ISBN 13: 9780309156110
Language: EN, FR, DE, ES & NL

Antibiotic Resistance Book Review:

Years of using, misusing, and overusing antibiotics and other antimicrobial drugs has led to the emergence of multidrug-resistant 'superbugs.' The IOM's Forum on Microbial Threats held a public workshop April 6-7 to discuss the nature and sources of drug-resistant pathogens, the implications for global health, and the strategies to lessen the current and future impact of these superbugs.

Antibiotic Resistance

Antibiotic Resistance
Author: Siouxsie Wiles
Publsiher: Bridget Williams Books
Total Pages: 136
Release: 2017-04-10
ISBN 10: 0947518665
ISBN 13: 9780947518660
Language: EN, FR, DE, ES & NL

Antibiotic Resistance Book Review:

In ten years’ time, will antibiotics still work? Have we let bacteria get the upper hand in the evolutionary arms race? In the 1920s the discovery of the antibiotic penicillin started a golden age of medicine. However, experts warn that the end of that age may be just a decade away. In this BWB Text, microbiologist Siouxsie Wiles explores the looming crisis of antibiotic resistance and its threat to New Zealand. Wiles concludes that New Zealand must do more to protect the public from a future without antibiotics.

Antibiotics and Antibiotic Resistance in the Environment

Antibiotics and Antibiotic Resistance in the Environment
Author: Carlos F. Amabile-Cuevas
Publsiher: CRC Press
Total Pages: 136
Release: 2015-12-30
ISBN 10: 1315679418
ISBN 13: 9781315679419
Language: EN, FR, DE, ES & NL

Antibiotics and Antibiotic Resistance in the Environment Book Review:

The presence of antibiotics, antibiotic resistance genes, and antibiotic resistant bacteria in the environment (i.e., outside of clinical settings, such as antibiotic-treated patients or antibiotic-impregnated locations, such as hospitals) is a cause of growing worldwide concern, as it reveals the extensive impact of antibiotic abuse and other huma

Superbugs

Superbugs
Author: Matt McCarthy
Publsiher: Penguin
Total Pages: 304
Release: 2019-05-21
ISBN 10: 0735217521
ISBN 13: 9780735217522
Language: EN, FR, DE, ES & NL

Superbugs Book Review:

International Bestseller "An amazing, informative book that changes our perspective on medicine, microbes and our future." --Siddhartha Mukherjee, MD, New York Times bestselling author of The Emperor of All Maladies A New York Times bestselling author shares this exhilarating story of cutting-edge science and the race against the clock to find new treatments in the fight against the antibiotic-resistant bacteria known as superbugs. Physician, researcher, and ethics professor Matt McCarthy is on the front lines of a groundbreaking clinical trial testing a new antibiotic to fight lethal superbugs, bacteria that have built up resistance to the life-saving drugs in our rapidly dwindling arsenal. This trial serves as the backdrop for the compulsively readable Superbugs, and the results will impact nothing less than the future of humanity. Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more. The proverbial ticking clock will keep readers on the edge of their seats. Can Dr. McCarthy save the lives of his patients infected with the deadly bacteria, who have otherwise lost all hope?

Antimicrobial Resistance in Developing Countries

Antimicrobial Resistance in Developing Countries
Author: Aníbal de J. Sosa,Denis K. Byarugaba,Carlos F. Amábile-Cuevas,Po-Ren Hsueh,Samuel Kariuki,Iruka N. Okeke
Publsiher: Springer Science & Business Media
Total Pages: 554
Release: 2009-10-08
ISBN 10: 0387893709
ISBN 13: 9780387893709
Language: EN, FR, DE, ES & NL

Antimicrobial Resistance in Developing Countries Book Review:

Avoiding infection has always been expensive. Some human populations escaped tropical infections by migrating into cold climates but then had to procure fuel, warm clothing, durable housing, and crops from a short growing season. Waterborne infections were averted by owning your own well or supporting a community reservoir. Everyone got vaccines in rich countries, while people in others got them later if at all. Antimicrobial agents seemed at first to be an exception. They did not need to be delivered through a cold chain and to everyone, as vaccines did. They had to be given only to infected patients and often then as relatively cheap injectables or pills off a shelf for only a few days to get astonishing cures. Antimicrobials not only were better than most other innovations but also reached more of the world’s people sooner. The problem appeared later. After each new antimicrobial became widely used, genes expressing resistance to it began to emerge and spread through bacterial populations. Patients infected with bacteria expressing such resistance genes then failed treatment and remained infected or died. Growing resistance to antimicrobial agents began to take away more and more of the cures that the agents had brought.

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses
Author: OECD,World Health Organization
Publsiher: OECD Publishing
Total Pages: 250
Release: 2020-04-01
ISBN 10: 1108864120
ISBN 13: 9781108864121
Language: EN, FR, DE, ES & NL

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses Book Review:

Antimicrobial resistance (AMR) is a biological mechanism whereby a microorganism evolves over time to develop the ability to become resistant to antimicrobial therapies such as antibiotics. The drivers of and potential solutions to AMR are complex, often spanning multiple sectors. The internationally recognized response to AMR advocates for a ‘One Health’ approach, which requires policies to be developed and implemented across human, animal, and environmental health.

Mechanisms of antibiotic resistance

Mechanisms of antibiotic resistance
Author: Jun Lin,Kunihiko Nishino,Marilyn C. Roberts,Marcelo Tolmasky,Rustam I. Aminov,Lixin Zhang
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2015-06-01
ISBN 10: 2889195260
ISBN 13: 9782889195268
Language: EN, FR, DE, ES & NL

Mechanisms of antibiotic resistance Book Review:

Antibiotics represent one of the most successful forms of therapy in medicine. But the efficiency of antibiotics is compromised by the growing number of antibiotic-resistant pathogens. Antibiotic resistance, which is implicated in elevated morbidity and mortality rates as well as in the increased treatment costs, is considered to be one of the major global public health threats (www.who.int/drugresistance/en/) and the magnitude of the problem recently prompted a number of international and national bodies to take actions to protect the public (http://ec.europa.eu/dgs/health_consumer/docs/road-map-amr_en.pdf: http://www.who.int/drugresistance/amr_global_action_plan/en/; http://www.whitehouse.gov/sites/default/files/docs/carb_national_strategy.pdf). Understanding the mechanisms by which bacteria successfully defend themselves against the antibiotic assault represent the main theme of this eBook published as a Research Topic in Frontiers in Microbiology, section of Antimicrobials, Resistance, and Chemotherapy. The articles in the eBook update the reader on various aspects and mechanisms of antibiotic resistance. A better understanding of these mechanisms should facilitate the development of means to potentiate the efficacy and increase the lifespan of antibiotics while minimizing the emergence of antibiotic resistance among pathogens.

Antimicrobial Resistance and Food Safety

Antimicrobial Resistance and Food Safety
Author: Chin-Yi Chen,Xianghe Yan,Charlene R. Jackson
Publsiher: Elsevier
Total Pages: 452
Release: 2015-04-15
ISBN 10: 0128013370
ISBN 13: 9780128013373
Language: EN, FR, DE, ES & NL

Antimicrobial Resistance and Food Safety Book Review:

Antimicrobial Resistance and Food Safety: Methods and Techniques introduces antimicrobial resistant food-borne pathogens, their surveillance and epidemiology, emerging resistance and resistant pathogens. This analysis is followed by a systematic presentation of currently applied methodology and technology, including advanced technologies for detection, intervention, and information technologies. This reference can be used as a practical guide for scientists, food engineers, and regulatory personnel as well as students in food safety, food microbiology, or food science. Includes analysis of all major pathogens of concern Provides many case studies and examples of fundamental research findings Presents recent advances in methodologies and analytical software Demonstrates risk assessment using information technologies in foodborne pathogens

One Health and the Politics of Antimicrobial Resistance

One Health and the Politics of Antimicrobial Resistance
Author: Laura H. Kahn
Publsiher: JHU Press
Total Pages: 200
Release: 2016-08-15
ISBN 10: 1421420058
ISBN 13: 9781421420059
Language: EN, FR, DE, ES & NL

One Health and the Politics of Antimicrobial Resistance Book Review:

By integrating the perspectives of both medicine and agriculture and exploring the history and science behind the widespread use of growth-promoting antibiotics, One Health and the Politics of Antimicrobial Resistance examines the controversy in a unique way while offering policy recommendations that all sides can accept.

Antibiotic Discovery and Development

Antibiotic Discovery and Development
Author: Thomas J. Dougherty,Michael J. Pucci
Publsiher: Springer Science & Business Media
Total Pages: 1127
Release: 2011-12-18
ISBN 10: 1461414008
ISBN 13: 9781461414001
Language: EN, FR, DE, ES & NL

Antibiotic Discovery and Development Book Review:

This volume covers all aspects of the antibiotic discovery and development process through Phase II/III. The contributors, a group of highly experienced individuals in both academics and industry, include chapters on the need for new antibiotic compounds, strategies for screening for new antibiotics, sources of novel synthetic and natural antibiotics, discovery phases of lead development and optimization, and candidate compound nominations into development. Beyond discovery , the handbook will cover all of the studies to prepare for IND submission: Phase I (safety and dose ranging), progression to Phase II (efficacy), and Phase III (capturing desired initial indications). This book walks the reader through all aspects of the process, which has never been done before in a single reference. With the rise of antibiotic resistance and the increasing view that a crisis may be looming in infectious diseases, there are strong signs of renewed emphasis in antibiotic research. The purpose of the handbook is to offer a detailed overview of all aspects of the problem posed by antibiotic discovery and development.

Antimicrobial Resistance in Agriculture

Antimicrobial Resistance in Agriculture
Author: Indranil Samanta,Samiran Bandyopadhyay
Publsiher: Academic Press
Total Pages: 392
Release: 2019-09-25
ISBN 10: 0128165235
ISBN 13: 9780128165232
Language: EN, FR, DE, ES & NL

Antimicrobial Resistance in Agriculture Book Review:

Antimicrobial Resistance in Agriculture: Perspective, Policy and Mitigation is a valuable industrial resource that addresses complex, multi-factorial topics regarding farm, wild, companion animals, fish, and how the environment plays an important role in amplification and transmission of resistant bugs into the human food chain. Information of phenotypical and genotypical properties of each bacterial genus associated with antimicrobial resistance, transmission dynamics from different reservoirs (food animals, poultry, fishes) and control measures with alternative therapy, such as phytobiotics and nanomaterials are provided. Researchers, scientists and practitioners will find this an essential resource on the judicial use of antibiotics in animals and humans. Explores all the genera of livestock and fish originated pathogenic bacteria associated with antimicrobial resistance Presents cutting-edge research on epigenetics, nanotechnology and intervention technologies Discusses transmission dynamics of resistance gene pools from different reservoirs, including food animals, poultry, fishes and the environment

Antibiotic Resistance Protocols

Antibiotic Resistance Protocols
Author: Stephen H. Gillespie,Timothy D. McHugh
Publsiher: Humana
Total Pages: 227
Release: 2010-04-16
ISBN 10: 1928374650XXX
ISBN 13: STANFORD:36105211741231
Language: EN, FR, DE, ES & NL

Antibiotic Resistance Protocols Book Review:

This book fully updates and builds upon its first edition. Beginning with chapters on epidemiology and population genetics, it continues with sections covering genomics and gene expressions, fitness mutation and physiology, and the detection of resistance.

Bacterial Resistance to Antimicrobials Second Edition

Bacterial Resistance to Antimicrobials  Second Edition
Author: Richard G. Wax,Kim Lewis,Abigail A. Salyers,Harry Taber
Publsiher: CRC Press
Total Pages: 448
Release: 2007-12-05
ISBN 10: 9781420008753
ISBN 13: 1420008757
Language: EN, FR, DE, ES & NL

Bacterial Resistance to Antimicrobials Second Edition Book Review:

The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Understanding mechanisms of resistance is crucial to the future of antimicrobial therapy. Extensively revised, with contributions from international leaders in their fields, Bacterial Resistance to Antimicrobials, Second Edition blends scientific and practical approaches to the social, economic, and medical issues related to this growing problem. The book begins with a history of antimicrobial agents and bacterial resistance, and outlines the forces that contributed to the abuse of antibiotics and precipitated the current crisis. It goes on to describe what is known about the ecology of antibiotic resistant bacteria and reveals the inadequacies in our understanding. Emphasizing public health aspects, the editors stress that significant progress will be made only by addressing the problem only as a public, worldwide, problem. Chapters on resistance mechanisms describe the latest findings on what makes different groups of bacteria susceptible or resistant to antibiotics. They reveal the staggering diversity of bacteria and the need for a foundational understanding that will stimulate development of antibiotics capable of avoiding resistance mechanisms. Examining the success and limitations of complementary approaches, such as combining ß-lactam antibiotics with ß-lactamase inhibitors, the book brings together information on resistance mechanisms in different groups of bacteria to help future efforts to more effectively develop and deploy antimicrobial therapies.

ODE PDE Analysis of Antibiotic Antimicrobial Resistance

ODE PDE Analysis of Antibiotic Antimicrobial Resistance
Author: William E. Schiesser
Publsiher: Academic Press
Total Pages: 122
Release: 2020-08-13
ISBN 10: 0128242507
ISBN 13: 9780128242506
Language: EN, FR, DE, ES & NL

ODE PDE Analysis of Antibiotic Antimicrobial Resistance Book Review:

ODE/PDE Analysis of Antibiotic/Antimicrobial Resistance: Programming in R presents mathematical models for antibiotic/antimicrobial resistance based on ordinary and partial differential equations (ODE/PDEs). Sections cover the basic ODE model, the detailed PDE model that gives the spatiotemporal distribution of four dependent variable components, including susceptible bacteria population density, resistant bacteria population density, plasmid number, and antibiotic concentration. The computer-based implementation of the example models is presented through routines coded (programmed) in R, a quality, open-source scientific computing system that is readily available from the Internet. As such, formal mathematics is minimized and no theorems and proofs are required. The PDE analysis is based on the method of lines (MOL), an established general algorithm for PDEs that is implemented with finite differences. Routines are available from a download link so that the example models can be executed without having to first study numerical methods and computer coding. Routines can then be applied to variations and extensions of the antibiotic/antimicrobial models, such as changes in the ODE/PDE parameters (constants) and the form of the model equations. Includes PDE routines based on the method of lines (MOL) for computer-based implementation of PDE models Offers transportable computer source codes for readers in R, with line-by-line code descriptions as it relates to mathematical model and algorithms Authored by a leading researcher and educator in PDE models

Antibiotic Policies Fighting Resistance

Antibiotic Policies  Fighting Resistance
Author: Ian M. Gould,Jos W.M. van der Meer
Publsiher: Springer Science & Business Media
Total Pages: 285
Release: 2007-09-12
ISBN 10: 0387708405
ISBN 13: 9780387708409
Language: EN, FR, DE, ES & NL

Antibiotic Policies Fighting Resistance Book Review:

This volume examines many of the crucial issues of resistance in a clinical context, with an emphasis on MRSA; surely the greatest challenge to our antibiotic and infection control policies that modern health care systems have ever seen. Other chapters explore the psychology of prescribing, modern management techniques as an adjunct to antibiotic policies, and the less obvious downsides of antibiotic use.

Antibiotic Resistance

Antibiotic Resistance
Author: Karl S. Drlica,David S. Perlin
Publsiher: FT Press
Total Pages: 288
Release: 2010-11-24
ISBN 10: 9780132117326
ISBN 13: 0132117320
Language: EN, FR, DE, ES & NL

Antibiotic Resistance Book Review:

Authored by two leading investigators, this book presents a thorough and authoritative overview of this multifaceted field of science. Pathogenic bacteria have been evolving and spreading resistance to diverse classes of antibiotics. As a result, we risk losing our ability to control and treat infectious diseases. Understanding antibiotic resistance, therefore, is becoming increasingly essential for a broad audience of healthcare professionals, biomedical and public health researchers, students, and policymakers. The authors answer questions such as: What is resistance? How does it emerge? How do common human activities contribute to resistance? What can we do about it? How can we strengthen our “first lines of defense” against resistance? Are there better ways to discover new antibiotics? What unique issues are associated with MRSA and viral influenza? In addition to defining and evaluating one of the most important emerging threats to public health, the authors explain what can be done to minimize risks to public health, and to preserve and extend the effectiveness of existing and new antibiotics.