Amphioxus Immunity

Amphioxus Immunity
Author: An-Long Xu
Publsiher: Elsevier
Total Pages: 304
Release: 2015-12-31
ISBN 10: 0128096470
ISBN 13: 9780128096475
Language: EN, FR, DE, ES & NL

Amphioxus Immunity Book Review:

Amphioxus Immunity: Tracing the Origin of Human Immunity covers a remarkable range of information about Amphioxus and its evolutionary context. This compilation of what is currently known about Amphioxus, with a sharp focus on its immune system, includes 13 topics, such as: Amphioxus as a model for understanding the evolution of vertebrates basic knowledge of immunology immune organs and cells of amphioxus a genomic and transcriptomic view of the Amphioxus immunity pattern recognition system in Amphioxus transcription factors in Amphioxus the complement system of Amphioxus the oxidative burst system in Amphioxus immune effectors in Amphioxus lipid signaling of immune response in Amphioxus apoptosis in amphioxus; primitive adaptive immune system of Amphioxus and future research directions This valuable reference book is loaded with information that will be useful for anyone who wishes to learn more about the origin of vertebrates and adaptive immunity. Provides new evidence on the origin of the adaptive immune system, the evolution of innate immunity, and evolution-stage specific immune defense mechanisms Not only presents the cells and molecules involved in the adaptive immune response in Amphioxus, but also characterizes the origination and evolution of the gene families and pathways involved in innate immunity Includes much pioneering work, from the molecular, genomic, and cellular to the individual level

Amphioxus Immunity

Amphioxus Immunity
Author: Anlong Xu
Publsiher: Unknown
Total Pages: 303
Release: 2011
ISBN 10: 9787030323163
ISBN 13: 7030323165
Language: EN, FR, DE, ES & NL

Amphioxus Immunity Book Review:

Advances in Comparative Immunology

Advances in Comparative Immunology
Author: Edwin L. Cooper
Publsiher: Springer
Total Pages: 1048
Release: 2018-08-07
ISBN 10: 3319767682
ISBN 13: 9783319767680
Language: EN, FR, DE, ES & NL

Advances in Comparative Immunology Book Review:

Immunologists, perhaps understandably, most often concentrate on the human immune system, an anthropocentric focus that has resulted in a dearth of information about the immune function of all other species within the animal kingdom. However, knowledge of animal immune function could help not only to better understand human immunology, but perhaps more importantly, it could help to treat and avoid the blights that affect animals, which consequently affect humans. Take for example the mass death of honeybees in recent years – their demise, resulting in much less pollination, poses a serious threat to numerous crops, and thus the food supply. There is a similar disappearance of frogs internationally, signaling ecological problems, among them fungal infections. This book aims to fill this void by describing and discussing what is known about non-human immunology. It covers various major animal phyla, its chapters organized in a progression from the simplest unicellular organisms to the most complex vertebrates, mammals. Chapters are written by experts, covering the latest findings and new research being conducted about each phylum. Edwin L. Cooper is a Distinguished Professor in the Laboratory of Comparative Immunology, Department of Neurobiology at UCLA’s David Geffen School of Medicine.

Evolution of Innate Immunity in Eukarya Advances and Implications

Evolution of Innate Immunity in Eukarya  Advances and Implications
Author: Jean L. Scholz,Ioannis Eleftherianos,Bostjan Kobe
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2022-05-06
ISBN 10: 2889761339
ISBN 13: 9782889761333
Language: EN, FR, DE, ES & NL

Evolution of Innate Immunity in Eukarya Advances and Implications Book Review:

Issues in Immunology Research 2011 Edition

Issues in Immunology Research  2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 1986
Release: 2012-01-09
ISBN 10: 146496405X
ISBN 13: 9781464964053
Language: EN, FR, DE, ES & NL

Issues in Immunology Research 2011 Edition Book Review:

Issues in Immunology Research / 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immunology Research. The editors have built Issues in Immunology Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunology Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues in Immunology Research 2012 Edition

Issues in Immunology Research  2012 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 289
Release: 2013-01-10
ISBN 10: 1481646370
ISBN 13: 9781481646376
Language: EN, FR, DE, ES & NL

Issues in Immunology Research 2012 Edition Book Review:

Issues in Immunology Research / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immunogenetics. The editors have built Issues in Immunology Research: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunogenetics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Changing Views of the Evolution of Immunity

Changing Views of the Evolution of Immunity
Author: Gary W. Litman,Larry J. Dishaw
Publsiher: Frontiers E-books
Total Pages: 135
Release: 2014-01-22
ISBN 10: 2889191710
ISBN 13: 9782889191710
Language: EN, FR, DE, ES & NL

Changing Views of the Evolution of Immunity Book Review:

The multitude of cells, signaling pathways, receptors, novel genetic recombination mechanisms and interactive pathways of receptor function and cell differentiation that constitute the vertebrate adaptive immune system are integrally linked with the multicomponent innate immune system. At first glance, the levels of complexity seen in both systems at the phylogenetic level of mammals present what seem to be insurmountable hurdles in terms of achieving a systematic understanding of the evolution of immunity. New research directions and approaches suggest that resolution of many long-standing questions in this area is now possible. Historically, immunologists considered lower vertebrates and invertebrates as “simpler” forms, i.e., they were expected to possess more basic (less layered) levels of immunological complexity and thus potentially would serve as important resources. By considering the systematic placement of representative species in the context of phylogeny, characterizing their immune receptors, co-receptors as well as accessory molecules and evaluating responses to immunologic stimuli, it was thought that a clearer picture of immune evolution would emerge. There is no doubt that this approach has achieved some notable successes but for the most part it has fallen short in terms of achieving a broad understanding of the immunologic needs of many relevant models and how adaptive change in immune function is effected. Even if a structurally relevant ortholog of an immune effector is identified in a model organism, there is no reason to assume that it functions in a corresponding manner in disparate phylogenetic taxa. For example, survival of a sessile marine invertebrate, whose anatomical form puts it in open and contiguous contact with a literal sea of microorganisms and viruses, would be thought to depend, at least in part, on a “capable” immune response; however, at present, we have no real understanding of how this is achieved in an integrated manner. Furthermore, questions arise as to whether or not phenomena that are considered integral components of vertebrate-type immunity such as memory, tolerance, somatic change and clonal selection exist in invertebrates and if their functions parallel those recognized in mammals. More often than not, our interpretations are guided by preconceived notions that are based on observations made in distant species that often do not apply to far- removed taxa. We anticipate that major advances in our understanding of this broad subject are now forthcoming as resources exist or are being developed for examining important model organisms in their natural environments instead of within the confines of in vitro systems of potentially remote physiological significance. Taking a wide range of hypotheses, observations and interpretations into account, in this special topic, contributors have developed a comprehensive overview emphasizing new directions and interpretations for understanding basic aspects of immunity that consider unique features inherent to various model systems, their life histories and habitats. Approaches applied with key model organisms maintained and confronted with relevant challenges under natural conditions are emphasized. Current concepts of self and nonself are addressed not only in terms of immunity but also reproductive fitness. How genetic variation in immune effector molecules is achieved and maintained in natural populations is examined; particular attention is directed to response interfaces that factor in symbiotic interactions. Gene expansion and mechanisms of genetic diversification are explored. How diverse molecules and a variety of effector cells contribute to our broad understanding of the evolution of a remarkably complex, integrated system and how this work is facilitating our understanding of mammalian immunity is addressed.

The M2 Macrophage

The M2 Macrophage
Author: Tamás Röszer
Publsiher: Springer Nature
Total Pages: 224
Release: 2020-08-03
ISBN 10: 3030504808
ISBN 13: 9783030504809
Language: EN, FR, DE, ES & NL

The M2 Macrophage Book Review:

Macrophages are core components of the innate immune system. Once activated, they may have either pro- or anti-inflammatory effects that include pathogen killing, safe disposal of apoptotic cells or tissue renewal. The activation state of macrophages is conceptualized by the so-called M1/M2 model of polarization. M2 macrophages are not simply antagonists of M1 macrophages; rather, they represent a network of tissue resident macrophages with roles in tissue development and organ homeostasis. M2 macrophages govern functions at the interfaces of immunity, tissue development and turnover, metabolism, and endocrine signaling. Dysfunction in M2 macrophages can ruin the healthy interplay between the immune system and metabolic processes, and lead to diseases such as insulin resistance, metabolic syndrome, and type 1 and 2 diabetes mellitus. Furthermore, M2 macrophages are essential for healthy tissue development and immunological self-tolerance. Worryingly, these functions of M2 macrophages can also be disrupted, resulting in tumor growth and autoimmunity. This book comprehensively discusses the biology of M2 macrophages, summarizes the current state of knowledge, and highlights key questions that remain unanswered.

Invertebrate Pathology

Invertebrate Pathology
Author: Andrew F. Rowley,Christopher J. Coates,Miranda W. Whitten
Publsiher: Oxford University Press
Total Pages: 624
Release: 2022-01-15
ISBN 10: 0198853750
ISBN 13: 9780198853756
Language: EN, FR, DE, ES & NL

Invertebrate Pathology Book Review:

This book assembles an international team of the leading specialists in the field to review the main diseases and pathologic manifestations of all the major invertebrate groups, whilst describing their emergence in contexts such as climate change and global food security.

The Evolution of the Immune System

The Evolution of the Immune System
Author: Davide Malagoli
Publsiher: Academic Press
Total Pages: 384
Release: 2016-07-21
ISBN 10: 012802013X
ISBN 13: 9780128020135
Language: EN, FR, DE, ES & NL

The Evolution of the Immune System Book Review:

The Evolution of the Immune System: Conservation and Diversification is the first book of its kind that prompts a new perspective when describing and considering the evolution of the immune system. Its unique approach summarizes, updates, and provides new insights on the different immune receptors, soluble factors, and immune cell effectors. Helps the reader gain a modern idea of the evolution of the immune systems in pluricellular organisms Provides a complete overview of the most studied and hot topics in comparative and evolutionary immunology Reflects the organisation of the immune system (cell-based, humoral [innate], humoral [adaptive]) without introducing further and misleading levels of organization Brings concepts and ideas on the evolution of the immune system to a wide readership

Handbook of Marine Model Organisms in Experimental Biology

Handbook of Marine Model Organisms in Experimental Biology
Author: Agnes Boutet,Bernd Schierwater
Publsiher: CRC Press
Total Pages: 485
Release: 2021-11-26
ISBN 10: 1000464334
ISBN 13: 9781000464337
Language: EN, FR, DE, ES & NL

Handbook of Marine Model Organisms in Experimental Biology Book Review:

The importance of molecular approaches for comparative biology and the rapid development of new molecular tools is unprecedented. The extraordinary molecular progress belies the need for understanding the development and basic biology of whole organisms. Vigorous international efforts to train the next-generation of experimental biologists must combine both levels – next generation molecular approaches and traditional organismal biology. This book provides cutting-edge chapters regarding the growing list of marine model organisms. Access to and practical advice on these model organisms have become a conditio sine qua non for a modern education of advanced undergraduate students, graduate students and postdocs working on marine model systems. Model organisms are not only tools they are also bridges between fields – from behavior, development and physiology to functional genomics. Key Features Offers deep insights into cutting-edge model system science Provides in-depth overviews of all prominent marine model organisms Illustrates challenging experimental approaches to model system research Serves as a reference book also for next-generation functional genomics applications Fills an urgent need for students Related Titles Jarret, R. L. & K. McCluskey, eds. The Biological Resources of Model Organisms (ISBN 978-1-1382-9461-5) Kim, S.-K. Healthcare Using Marine Organisms (ISBN 978-1-1382-9538-4) Mudher, A. & T. Newman, eds. Drosophila: A Toolbox for the Study of Neurodegenerative Disease (ISBN 978-0-4154-1185-1) Green, S. L. The Laboratory Xenopus sp. (ISBN 978-1-4200-9109-0)

Bacterial Antigens Advances in Research and Application 2013 Edition

Bacterial Antigens   Advances in Research and Application  2013 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 150
Release: 2013-06-21
ISBN 10: 1481685449
ISBN 13: 9781481685443
Language: EN, FR, DE, ES & NL

Bacterial Antigens Advances in Research and Application 2013 Edition Book Review:

Bacterial Antigens—Advances in Research and Application: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Bacterial Polysaccharides. The editors have built Bacterial Antigens—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Bacterial Polysaccharides in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Bacterial Antigens—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Across the Bridge

Across the Bridge
Author: Henry Gee
Publsiher: University of Chicago Press
Total Pages: 288
Release: 2018-07-04
ISBN 10: 022640319X
ISBN 13: 9780226403199
Language: EN, FR, DE, ES & NL

Across the Bridge Book Review:

Our understanding of vertebrate origins and the backbone of human history evolves with each new fossil find and DNA map. Many species have now had their genomes sequenced, and molecular techniques allow genetic inspection of even non-model organisms. But as longtime Nature editor Henry Gee argues in Across the Bridge, despite these giant strides and our deepening understanding of how vertebrates fit into the tree of life, the morphological chasm between vertebrates and invertebrates remains vast and enigmatic. As Gee shows, even as scientific advances have falsified a variety of theories linking these groups, the extant relatives of vertebrates are too few for effective genetic analysis. Moreover, the more we learn about the species that do remain—from sea-squirts to starfish—the clearer it becomes that they are too far evolved along their own courses to be of much use in reconstructing what the latest invertebrate ancestors of vertebrates looked like. Fossils present yet further problems of interpretation. Tracing both the fast-changing science that has helped illuminate the intricacies of vertebrate evolution as well as the limits of that science, Across the Bridge helps us to see how far the field has come in crossing the invertebrate-to-vertebrate divide—and how far we still have to go.

Advanced Pharmacology for Prescribers

Advanced Pharmacology for Prescribers
Author: Brent Q. Luu, PharmD, BCPS, BCACP,Gerald Kayingo, PhD, PA-C,Virginia McCoy Hass, DNP, MSN, RN, FNP-C, PA-C
Publsiher: Springer Publishing Company
Total Pages: 848
Release: 2021-01-13
ISBN 10: 0826195474
ISBN 13: 9780826195470
Language: EN, FR, DE, ES & NL

Advanced Pharmacology for Prescribers Book Review:

Delivers the critical information primary care providers need to be thoroughly informed prescribers This unique resource—an evidence-based pharmacology text and reference for advanced practice students and clinicians—guides users in analyzing the pharmacological foundations of drug therapy and fosters the development of sound clinical judgment in determining the appropriate medication for every patient across the lifespan. Targeting the specific needs of APRN and PA students and clinicians, the text is a “bridge” between standard, lengthy pharmacology texts and quick pocket references that lack information regarding key pharmacotherapy principles. Featuring an applied therapeutic approach to major disorders and their pharmacologic treatment, the book examines how medications act on the body and visa versa, while teaching the rationale for using specific therapeutic agents or drug classes. Each chapter includes case studies that apply the concepts discussed, relevant diagnostic studies, applicable guidelines, genomics, and important lifespan considerations. Of special interest is a chapter on pharmacogenetics explaining the basic principles underlying our current understanding of genetic variations in response to pharmacotherapy and adverse drug reactions. Easily digestible chapters include objectives and review questions. Ancillary resources include an instructor manual with learning objectives, chapter summaries, and case studies; chapter PowerPoint slides; test bank; and image bank. Key Features: Delivers an applied, evidence-based foundation on the basic science underlying prescribing Targets the specific needs of APRN and PA students and professionals and related healthcare providers Provides clinical decision-making tools and principles to support sound prescribing judgment Focuses on synthesizing drugs to manage commonly occurring disorders Includes strategies for addressing the needs of specific populations throughout the lifespan Includes abundant case studies illuminating key concepts Includes a robust instructor manual with learning objectives, chapter summaries, and case studies; PowerPoint slides; test bank; and image bank. Purchase includes access to the eBook for use on most mobile devices or computers.

Cancer New Insights for the Healthcare Professional 2012 Edition

Cancer  New Insights for the Healthcare Professional  2012 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 3784
Release: 2012-12-10
ISBN 10: 1464969671
ISBN 13: 9781464969676
Language: EN, FR, DE, ES & NL

Cancer New Insights for the Healthcare Professional 2012 Edition Book Review:

Cancer: New Insights for the Healthcare Professional / 2012 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional / 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer: New Insights for the Healthcare Professional / 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Issues in Immunology Research 2013 Edition

Issues in Immunology Research  2013 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 1230
Release: 2013-05-01
ISBN 10: 1490107223
ISBN 13: 9781490107226
Language: EN, FR, DE, ES & NL

Issues in Immunology Research 2013 Edition Book Review:

Issues in Immunology Research / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Immunochemistry. The editors have built Issues in Immunology Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immunochemistry in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Immunology Research / 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

RNA DNA and Cancer

RNA DNA and Cancer
Author: Joseph G. Sinkovics
Publsiher: Springer
Total Pages: 815
Release: 2016-04-01
ISBN 10: 3319222791
ISBN 13: 9783319222790
Language: EN, FR, DE, ES & NL

RNA DNA and Cancer Book Review:

In this book, the author Joseph G. Sinkovics liberally shares his views on the cancer cell which he has been observing in vivo and in vitro, over a life time. Readers will learn how, as an inherent faculty of the RNA/DNA complex, the primordial cell survival pathways are endogenously reactivated in an amplified or constitutive manner in the multicellular host, and are either masquerading as self-elements or as placentas, to which the multicellular host is evolutionarily trained to extend full support. The host obliges. The author explains that there is no such evidence that “malignantly transformed” human cells survive in nature. However, when cared for in the laboratory, these cells live and replicate as immortalized cultures. These cells retain their vitality upon storage in liquid nitrogen. One can only imagine an astrophysical environment in which such cells could survive; perhaps, first their seemingly humble exosomes would populate that environment. Immortal cell populations so created may survive as individuals, or may even re-organize themselves into multicellular colonies, as representatives of life for the duration of the Universe. This thought-provoking book is the work of a disciplined investigator and clinician with an impeccable reputation, and he enters a territory that very few if any before him have approached from the same angles. It will appeal to researchers with an interest in cell survival pathways and those researching cancer cells.

Invertebrate Zoology

Invertebrate Zoology
Author: Bernd Schierwater,Rob DeSalle
Publsiher: CRC Press
Total Pages: 644
Release: 2021-07-08
ISBN 10: 148223582X
ISBN 13: 9781482235821
Language: EN, FR, DE, ES & NL

Invertebrate Zoology Book Review:

Invertebrate Zoology: A Tree of Life Approach is a comprehensive and authoritative textbook adopting an explicitly phylogenetic organization. Most of the classical anatomical and morphological work has not been changed – it established the foundation of Invertebrate Zoology. With the explosion of Next-Generation Sequencing approaches, there has been a sea-change in the recognized phylogenetic relationships among and between invertebrate lineages. In addition, the merger of evolutionary and developmental biology (evo-devo) has dramatically contributed to changes in the understanding of invertebrate biology. Synthesizing these three approaches (classical morphology, sequencing data, and evo-devo studies) offers students an entirely unique perspective of invertebrate diversity. Key Features One of the first textbooks to combine classical morphological approaches and newer evo-devo and Next-Generation Sequencing approaches to address Invertebrate Zoology Organized along taxonomic lines in accord with the latest understanding of invertebrate phylogeny Will provide background in basic systematic analysis useful within any study of biodiversity A wealth of ancillary materials for students and teachers, including downloadable figures, lecture slides, web links, and phylogenetic data matrices

Marine OMICS

Marine OMICS
Author: Se-Kwon Kim
Publsiher: CRC Press
Total Pages: 724
Release: 2016-11-18
ISBN 10: 1482258218
ISBN 13: 9781482258219
Language: EN, FR, DE, ES & NL

Marine OMICS Book Review:

This book provides comprehensive coverage on current trends in marine omics of various relevant topics such as genomics, lipidomics, proteomics, foodomics, transcriptomics, metabolomics, nutrigenomics, pharmacogenomics and toxicogenomics as related to and applied to marine biotechnology, molecular biology, marine biology, marine microbiology, environmental biotechnology, environmental science, aquaculture, pharmaceutical science and bioprocess engineering.

Current Topics in Innate Immunity

Current Topics in Innate Immunity
Author: John D. Lambris
Publsiher: Springer Science & Business Media
Total Pages: 432
Release: 2007-09-07
ISBN 10: 0387717676
ISBN 13: 9780387717678
Language: EN, FR, DE, ES & NL

Current Topics in Innate Immunity Book Review:

In the post genomic era, understanding of the innate immune system is enriched by findings on the specificity of innate immune reactions as well as to novel functions that do not strictly correlate with immunological defense and surveillance, immune modulation or inflammation. This volume covers natural killer cells, mast cells, phagocytes, toll-like receptors, complement, host defense in plants and invertebrates, evasion strategies of microorganisms, pathophysiology, protein structures, design of therapeutics, and experimental approaches.