A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy
Author: Rajan Mariappan
Publsiher: Academic Press
Total Pages: 330
Release: 2021-03-15
ISBN 10: 0128244844
ISBN 13: 9780128244845
Language: EN, FR, DE, ES & NL

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy Book Review:

A Mechanistic Approach to Medicines for Tuberculosis Nanotherapy examines drug carrier development for controlled, targeted, pH and stimuli responsive drug releases for tuberculosis. The book provides in-depth information about mycobacterium tuberculosis, tuberculosis formation, and synthetic procedures for carrier synthesis, characterizations and mechanistic approaches. Key topics include the properties and functions of nanomedicines and how they might be applied for clinical diagnosis and treatment. Emphasis is placed on the basic fundamentals, biomaterial formulations, design principles, fabrication techniques, and transitioning bench-to-bed clinical applications. This book is useful for new researchers who focus on nanomedicine, stem cell therapy and bone tissue engineering. In addition, it introduces experienced researchers and clinicians to key trends, thus increasing their knowledge in drug discovery for tuberculosis and nanomedicine. Features the most notable uses of drug for tuberculosis treatment, including novel advances in materials Assesses new agents and chemical compounds against tuberculosis Examines the interaction of new technologies to discover ways to treat tuberculosis more effectively and efficiently

Nanotechnology Based Approaches for Tuberculosis Treatment

Nanotechnology Based Approaches for Tuberculosis Treatment
Author: Prashant Kesharwani
Publsiher: Academic Press
Total Pages: 284
Release: 2020-06-10
ISBN 10: 0128226110
ISBN 13: 9780128226117
Language: EN, FR, DE, ES & NL

Nanotechnology Based Approaches for Tuberculosis Treatment Book Review:

Nanotechnology Based Approaches for Tuberculosis Treatment discusses multiple nanotechnology-based approaches that may help overcome persisting limitations of conventional and traditional treatments. The book summarizes the types of nano drugs, their synthesis, formulation, characterization and applications, along with the most important administration routes. It also explores recent advances and achievements regarding therapeutic efficacy and provides possible future applications in this field. It will be a useful resource for investigators, pharmaceutical researchers, innovators and scientists working on technology advancements in the areas of targeted therapies, nano scale imaging systems, and diagnostic modalities in tuberculosis. Addresses the gap between nanomedicine late discovery and early development of tuberculosis therapeutics Explores tuberculosis nanomedicine standardization and characterization with newly developed treatment, diagnostic and treatment monitoring modalities Covers the field thoroughly, from the pathogenesis of tuberculosis and multi-drug resistant mycobacterium tuberculosis, to treatment approaches using nanotechnology and different nanocarriers

Handbook of Research on Nano Strategies for Combatting Antimicrobial Resistance and Cancer

Handbook of Research on Nano Strategies for Combatting Antimicrobial Resistance and Cancer
Author: Saravanan, Muthupandian,Gopinath, Venkatraman,Deekonda, Karthik
Publsiher: IGI Global
Total Pages: 559
Release: 2021-02-12
ISBN 10: 1799850501
ISBN 13: 9781799850502
Language: EN, FR, DE, ES & NL

Handbook of Research on Nano Strategies for Combatting Antimicrobial Resistance and Cancer Book Review:

Multidrug-resistant bacteria play a significant role in public health by destroying the potency of existing antibiotics. Meanwhile, cancer remains one of the most common health problems that impact society, resulting in many deaths worldwide. Novel strategies are required to combat antimicrobial resistance and create efficient anticancer drugs that could revolutionize treatment. Nanomedicine is one such innovation that plays a significant role in developing alternative and more effective treatment strategies for antimicrobial resistance and cancer theranostics. The Handbook of Research on Nano-Strategies for Combatting Antimicrobial Resistance and Cancer is an essential scholarly resource that examines (1) how to overcome the existing, traditional approaches to combat antimicrobial resistance and cancer; (2) how to apply multiple mechanisms to target the cancer cells and microbes; and (3) how the nanomaterials can be used as carriers. Featuring a range of topics such as bacteriophage, nanomedicine, and oncology, this book is ideal for molecular biologists, microbiologists, nanotechnologists, academicians, chemists, pharmacists, oncologists, researchers, healthcare professionals, and students.

Bioactive Food Components Activity in Mechanistic Approach

Bioactive Food Components Activity in Mechanistic Approach
Author: Cinthia Bau Betim Cazarin,Juliano Lemos Bicas,Glaucia Maria Pastore,Mario Roberto Marostica Junior
Publsiher: Academic Press
Total Pages: 256
Release: 2021-11-23
ISBN 10: 0128225904
ISBN 13: 9780128225905
Language: EN, FR, DE, ES & NL

Bioactive Food Components Activity in Mechanistic Approach Book Review:

Bioactive Food Components Activity in Mechanistic Approach presents the role of functional foods and bioactive compounds in inflammation. This book focuses on bioactive compounds, including phenolics, prebiotics, carotenoids, tocopherols, bioactive peptides, probiotics, polyunsaturated and monounsaturated fatty acids, and describes their actions in several diseases, mainly obesity and co-morbidities, inflammatory bowel disease, cognitive decline and cancer, and aging. Intended for food, nutrition, and nutraceutical researchers, as well as those studying related fields, the book offers a mechanistic approach that is currently lacking in the market. Explores the mechanistic approach of functional foods in health and disease Contains definitions, case studies, applications, literature reviews, recent developments and text boxes Provides coverage of phenolic compounds, prebiotics and probiotics, carotenoids, tocopherols, bioactive peptides, polyunsaturated and monounsaturated fatty acids, and sulfur compounds

Nanoparticle Drug Delivery Systems for Cancer Treatment

Nanoparticle Drug Delivery Systems for Cancer Treatment
Author: Hala Gali-Muhtasib,Racha Chouaib
Publsiher: CRC Press
Total Pages: 326
Release: 2020-02-19
ISBN 10: 1000681416
ISBN 13: 9781000681413
Language: EN, FR, DE, ES & NL

Nanoparticle Drug Delivery Systems for Cancer Treatment Book Review:

In recent years, nanoparticles—bionanomaterials with specific physicochemical properties—have gained a great deal of scientific interest owing to their unique structure. Nanoparticle-based drugs are now widely regarded as a safer, more precise, and more effective mode of cancer therapy, considering their ability to enhance drug bioavailability, improve site-specific drug delivery, and protect nontarget tissues from toxic therapeutic drugs. This book compiles and details cutting-edge research in nanomedicine from an interdisciplinary team of international cancer researchers who are currently revolutionizing drug delivery techniques through the development of nanomedicines and nanotheranostics. Edited by Hala Gali-Muhtasib and Racha Chouaib, two prominent cancer researchers, this book will appeal to anyone involved in nanotechnology, cancer therapy, or drug delivery research.

Biomedical Applications of Functionalized Nanomaterials

Biomedical Applications of Functionalized Nanomaterials
Author: Bruno Sarmento,Jose Das Neves
Publsiher: William Andrew
Total Pages: 778
Release: 2018-03-01
ISBN 10: 0323508790
ISBN 13: 9780323508797
Language: EN, FR, DE, ES & NL

Biomedical Applications of Functionalized Nanomaterials Book Review:

Biomedical Applications of Functionalized Nanomaterials: Concepts, Development and Clinical Translation presents a concise overview of the most promising nanomaterials functionalized with ligands for biomedical applications. The first section focuses on current strategies for identifying biological targets and screening of ligand to optimize anchoring to nanomaterials, providing the foundation for the remaining parts. Section Two covers specific applications of functionalized nanomaterials in therapy and diagnostics, highlighting current practice and addressing major challenges, in particular, case studies of successfully developed and marketed functionalized nanomaterials. The final section focuses on regulatory issues and clinical translation, providing a legal framework for their use in biomedicine. This book is an important reference source for worldwide drug and medical devices policymakers, biomaterials scientists and regulatory bodies. Provides an overview of the methodologies for biological target identification and ligand screening Includes case studies showing the development of functionalized nanomaterials and their biomedical applications Highlights the importance of functionalized nanomaterials for drug delivery, diagnostics and regenerative medicine applications

Nanocarrier Technologies

Nanocarrier Technologies
Author: M. Reza Mozafari
Publsiher: Springer Science & Business Media
Total Pages: 226
Release: 2006-09-24
ISBN 10: 1402050410
ISBN 13: 9781402050411
Language: EN, FR, DE, ES & NL

Nanocarrier Technologies Book Review:

Designed as an advanced survey of the field, this book describes the key research parameters of nanocarrier technologies. It is the first book with this topic. It comprises a collection of scientific articles from top research people in the field and provides an up-to-date source containing recent citation and bibliography. The book is an indispensable source of information for new researchers and scientists.

Metal Nanoparticles in Microbiology

Metal Nanoparticles in Microbiology
Author: Mahendra Rai,Nelson Duran
Publsiher: Springer Science & Business Media
Total Pages: 303
Release: 2011-04-02
ISBN 10: 3642183123
ISBN 13: 9783642183126
Language: EN, FR, DE, ES & NL

Metal Nanoparticles in Microbiology Book Review:

Following an introduction to biogenic metal nanoparticles, this book presents how they can be biosynthesized using bacteria, fungi and yeast, as well as their potential applications in biomedicine. It is shown that the synthesis of nanoparticles using microbes is eco-friendly and results in reproducible metal nanoparticles of well-defined sizes, shapes and structures. This biotechnological approach based on the process of biomineralization exploits the effectiveness and flexibility of biological systems. Chapters include practical protocols for microbial synthesis of nanoparticles and microbial screening methods for isolating a specific nanoparticle producer as well as reviews on process optimization, industrial scale production, biomolecule-nanoparticle interactions, magnetosomes, silver nanoparticles and their numerous applications in medicine, and the application of gold nanoparticles in developing sensitive biosensors.

Bacterial Cellular Metabolic Systems

Bacterial Cellular Metabolic Systems
Author: K. Shimizu
Publsiher: Elsevier
Total Pages: 496
Release: 2013-03-26
ISBN 10: 1908818204
ISBN 13: 9781908818201
Language: EN, FR, DE, ES & NL

Bacterial Cellular Metabolic Systems Book Review:

The metabolic regulation of a cell system is of critical importance in systems biology, and a robust model of these mechanisms is essential in predicting the effects on the metabolism of both the culture environment and the knockout of specific genes. Bacterial cellular metabolic systems focuses on this highly topical subject in relation to culture environment and provides a detailed analysis from gene level to metabolic level regulation, as well as offering a discussion of the most recent modelling approaches. The book begins with an introduction to metabolic mechanisms and to the metabolic regulation of a cell, before moving on to discussing the action of global regulators in response to a specific culture environment. The second half of the book examines conventional flux balance analysis and its applications, 13C-metabolic flux analysis, and the effect of a specific gene knockout on the metabolism. Comprehensive account of metabolic regulation via global regulators in response to changes in the culture environment Basic formulation of 13C-metabolic flux analysis based on 13C-labelling experiments Systems biology approach for the modelling and computer simulation of the main metabolic pathways of a cell system

Nanobiotechnology in Diagnosis Drug Delivery and Treatment

Nanobiotechnology in Diagnosis  Drug Delivery and Treatment
Author: Mahendra Rai,Mehdi Razzaghi-Abyaneh,Avinash P. Ingle
Publsiher: John Wiley & Sons
Total Pages: 416
Release: 2020-11-17
ISBN 10: 1119671868
ISBN 13: 9781119671862
Language: EN, FR, DE, ES & NL

Nanobiotechnology in Diagnosis Drug Delivery and Treatment Book Review:

Presents nanobiotechnology in drug delivery and disease management Featuring contributions from noted experts in the field, this book highlights recent advances in the nano-based drug delivery systems. It also covers the diagnosis and role of various nanomaterials in the management of infectious diseases and non-infectious disorders, such as cancers and other malignancies and their role in future medicine. Nanobiotechnology in Diagnosis, Drug Delivery and Treatment starts by introducing how nanotechnology has revolutionized drug delivery, diagnosis, and treatments of diseases. It then focuses on the role of various nanocomposites in diagnosis, drug delivery, and treatment of diseases like cancer, Alzheimer's disease, diabetes, and many others. Next, it discusses the application of a variety of nanomaterials in the diagnosis and management of gastrointestinal tract disorders. The book explains the concept of nanotheranostics in detail and its role in effective monitoring of drug response, targeted drug delivery, enhanced drug accumulation in the target tissues, sustained as well as triggered release of drugs, and reduction in adverse effects. Other chapters cover aptamer-incorporated nanoparticle systems; magnetic nanoparticles; theranostics and vaccines; toxicological concerns of nanomaterials used in nanomedicine; and more. Provides a concise overview of state-of-the-art nanomaterials and their application like drug delivery in infectious diseases and non-infectious disorders Highlights recent advances in the nano-based drug delivery systems and role of various nanomaterials Introduces nano-based sensors which detect various pathogens Covers the use of nanodevices in diagnostics and theranostics Nanobiotechnology in Diagnosis, Drug Delivery and Treatment is an ideal book for researchers and scientists working in various disciplines such as microbiology, biotechnology, nanotechnology, pharmaceutical biotechnology, pharmacology, pharmaceutics, and nanomedicine.

Targeted Drug Delivery Concepts and Design

Targeted Drug Delivery   Concepts and Design
Author: Padma V. Devarajan,Sanyog Jain
Publsiher: Springer
Total Pages: 790
Release: 2014-12-08
ISBN 10: 3319113550
ISBN 13: 9783319113555
Language: EN, FR, DE, ES & NL

Targeted Drug Delivery Concepts and Design Book Review:

This authoritative volume explores the fundamental concepts and numerous applications of targeted delivery of drugs to the body. This compilation has been divided into eight sections comprised of the basic principles of drug targeting, disease and organ/organelle-based targeting, passive and active targeting strategies, and various advanced drug delivery tools such as functionalized lipidic, polymeric and inorganic nanocarriers. Together, the twenty-three chapters cover a wide range of topics in the field, including tumor and hepatic targeting, polymer-drug conjugates, nanoemulsion, physical and biophysical characteristics of nanoparticles, and in vivo imaging techniques, among others. The book also examines advanced characterization techniques, regulatory hurdles and toxicity-related issues that are key features for successful commercialization of targeted drug delivery system products. Targeted Drug Delivery is a comprehensive reference guide for drug delivery researchers, both beginners and those already working in the field.

Drug Benefits and Risks

Drug Benefits and Risks
Author: Chris J. van Boxtel,Budiono Santoso,I. Ralph Edwards
Publsiher: John Wiley & Sons
Total Pages: 738
Release: 2001-11-28
ISBN 10: 9780471899273
ISBN 13: 0471899275
Language: EN, FR, DE, ES & NL

Drug Benefits and Risks Book Review:

This is an inclusive reference exploring the scientific basis and practice of drug therapy. The key concept is to look at the balance between the benefits and risks of drugs but in this context also the social impact which drugs have in modern societies is highlighted. Taking an evidence-based approach to the problem, the practice of clinical pharmacology and pharmacotherapy in the developing as well as the developed world is examined. For this purpose the book * Covers general clinical pharmacology, pharmacology of various drug groups and the treatments specific to various diseases * Gives guidance on how doctors should act so that drugs can be used effectively and safely * Encourages the rational use of drugs in society This book brings together a large amount of excellent content that will be invaluable for anyone working within, or associated with, the field of clinical pharmacology and pharmacotherapy - undergraduates, postgraduates, regulatory authorities and the pharmaceutical industry.

Nanopharmaceuticals Principles and Applications Vol 3

Nanopharmaceuticals  Principles and Applications Vol  3
Author: Vinod Kumar Yata,Shivendu Ranjan,Nandita Dasgupta,Eric Lichtfouse
Publsiher: Springer Nature
Total Pages: 340
Release: 2020-08-19
ISBN 10: 3030471209
ISBN 13: 9783030471200
Language: EN, FR, DE, ES & NL

Nanopharmaceuticals Principles and Applications Vol 3 Book Review:

This book is the third volume on this subject and focuses on the recent advances of nanopharmaceuticals in cancer, dental, dermal and drug delivery applications and presents their safety, toxicity and therapeutic efficacy. The book also includes the transport phenomenon of nanomaterials and important pathways for drug delivery applications. It goes on to explain the toxicity of nanoparticles to different physiological systems and methods used to assess this for different organ systems using examples of in vivo systems.

Nanostructures for Antimicrobial Therapy

Nanostructures for Antimicrobial Therapy
Author: Anton Ficai,Alexandru Mihai Grumezescu
Publsiher: Elsevier
Total Pages: 722
Release: 2017-05-29
ISBN 10: 0323461514
ISBN 13: 9780323461511
Language: EN, FR, DE, ES & NL

Nanostructures for Antimicrobial Therapy Book Review:

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Nanotechnology in Diagnosis Treatment and Prophylaxis of Infectious Diseases

Nanotechnology in Diagnosis  Treatment and Prophylaxis of Infectious Diseases
Author: Mahendra Rai,Kateryna Kon
Publsiher: Academic Press
Total Pages: 344
Release: 2015-05-23
ISBN 10: 0128014717
ISBN 13: 9780128014714
Language: EN, FR, DE, ES & NL

Nanotechnology in Diagnosis Treatment and Prophylaxis of Infectious Diseases Book Review:

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections

Understanding Tuberculosis

Understanding Tuberculosis
Author: Pere-Joan Cardona
Publsiher: BoD – Books on Demand
Total Pages: 564
Release: 2012-02-15
ISBN 10: 953307938X
ISBN 13: 9789533079387
Language: EN, FR, DE, ES & NL

Understanding Tuberculosis Book Review:

Mycobacterium tuberculosis is a disease that is transmitted through aerosol. This is the reason why it is estimated that a third of humankind is already infected by Mycobacterium tuberculosis. The vast majority of the infected do not know about their status. Mycobacterium tuberculosis is a silent pathogen, causing no symptomatology at all during the infection. In addition, infected people cannot cause further infections. Unfortunately, an estimated 10 per cent of the infected population has the probability to develop the disease, making it very difficult to eradicate. Once in this stage, the bacilli can be transmitted to other persons and the development of clinical symptoms is very progressive. Therefore the diagnosis, especially the discrimination between infection and disease, is a real challenge. In this book, we present the experience of worldwide specialists on the diagnosis, along with its lights and shadows.

Surface Modification of Nanoparticles for Targeted Drug Delivery

Surface Modification of Nanoparticles for Targeted Drug Delivery
Author: Yashwant V Pathak
Publsiher: Springer
Total Pages: 499
Release: 2019-03-11
ISBN 10: 3030061159
ISBN 13: 9783030061159
Language: EN, FR, DE, ES & NL

Surface Modification of Nanoparticles for Targeted Drug Delivery Book Review:

This unique book is the only one to discuss various new techniques developed to enhance the application of nanoparticulate drug delivery systems using surface modification of nanoparticles. The understanding of the surface characteristics nano-particles is growing significantly with the advent of new analytical techniques. Polymer chemistry is contributing to the development of many new versatile polymers which have abilities to accommodate many different, very reactive chemical groups, and can be used as a diagnostic tool, for better targeting, for more effective therapeutic results as well as for reducing the toxic and side effects of the drugs. Surface modification of such polymeric nanoparticles has been found by many scientists to enhance the application of nanoparticles and also allows the nano particles to carry specific drug molecule and disease /tumor specific antibodies which refine and improve drug delivery. Surface Modification of Nanoparticles for Targeted Drug Delivery is a collection essential information with various applications of surface modification of nanoparticles and their disease specific applications for therapeutic purposes.

Polymer Nanoparticles for Nanomedicines

Polymer Nanoparticles for Nanomedicines
Author: Christine Vauthier,Gilles Ponchel
Publsiher: Springer
Total Pages: 641
Release: 2017-01-07
ISBN 10: 3319414216
ISBN 13: 9783319414218
Language: EN, FR, DE, ES & NL

Polymer Nanoparticles for Nanomedicines Book Review:

This volume serves as a valuable handbook for the development of nanomedicines made of polymer nanoparticles because it provides researchers, students, and entrepreneurs with all the material necessary to begin their own projects in this field. Readers will find protocols to prepare polymer nanoparticles using different methods, since these are based on the variety of experiences that experts encounter in the field. In addition, complex topics such as, the optimal characterization of polymer nanoparticles is discussed, as well as practical guidelines on how to formulate polymer nanoparticles into nanomedicines, and how to modify the properties of nanoparticles to give them the different functionalities required to become an efficient nanomedicine for different clinical applications. The book also discusses the translation of technology from research to practice, considering aspects related to industrialization of preparation and aspects of regulatory and clinical development.

CMBEBIH 2019

CMBEBIH 2019
Author: Almir Badnjevic,Ranko Škrbić,Lejla Gurbeta Pokvić
Publsiher: Springer
Total Pages: 782
Release: 2019-05-10
ISBN 10: 3030179710
ISBN 13: 9783030179717
Language: EN, FR, DE, ES & NL

CMBEBIH 2019 Book Review:

This volume gathers the proceedings of the International Conference on Medical and Biological Engineering, which was held from 16 to 18 May 2019 in Banja Luka, Bosnia and Herzegovina. Focusing on the goal to ‘Share the Vision’, it highlights the latest findings, innovative solutions and emerging challenges in the field of Biomedical Engineering. The book covers a wide range of topics, including: biomedical signal processing, medical physics, biomedical imaging and radiation protection, biosensors and bioinstrumentation, bio-micro/nano technologies, biomaterials, biomechanics, robotics and minimally invasive surgery, and cardiovascular, respiratory and endocrine systems engineering. Further topics include bioinformatics and computational biology, clinical engineering and health technology assessment, health informatics, e-health and telemedicine, artificial intelligence and machine learning in healthcare, as well as pharmaceutical and genetic engineering. Given its scope, the book provides academic researchers, clinical researchers and professionals alike with a timely reference guide to measures for improving the quality of life and healthcare.

Nanoparticulate Drug Delivery Systems

Nanoparticulate Drug Delivery Systems
Author: Yoon Yeo
Publsiher: John Wiley & Sons
Total Pages: 324
Release: 2013-02-25
ISBN 10: 1118570510
ISBN 13: 9781118570517
Language: EN, FR, DE, ES & NL

Nanoparticulate Drug Delivery Systems Book Review:

Frank discussions of opportunities and challenges point the way to new, more effective drug delivery systems Interest in nanomedicine has grown tremendously, fueled by the expectation that continued research will lead to the safe, efficient, and cost-effective delivery of drugs or imaging agents to human tissues and organs. The field, however, has faced several challenges attempting to translate novel ideas into clinical benefits. With contributions from an international team of leading nanomedicine researchers, this book provides a practical assessment of the possibilities and the challenges of modern nanomedicine that will enable the development of clinically effective nanoparticulate drug delivery products and systems. Nanoparticulate Drug Delivery Systems focuses on the rationales and preclinical evaluation of new nanoparticulate drug carriers that have yet to be thoroughly reviewed in the literature. The first chapter sets the stage with a general overview of targeted nanomedicine. The book then explores new and promising nanoparticulate drug delivery systems, including: Lipid nanoparticles for the delivery of nucleic acids Multifunctional dendritic nanocarriers Polymer drug nanoconjugates Next, the book presents new opportunities and challenges for nanoparticulate drug delivery systems, including: Clearance of nanoparticles during circulation Drug delivery strategies for combatting multiple drug resistance Toxicological assessment of nanomedicine Chapters offer state-of-the-technology reviews with extensive references to facilitate further investigation. Moreover, each chapter concludes with an expert assessment of remaining challenges, pointing the way to solutions and new avenues of research. With its frank discussions of opportunities and challenges, Nanoparticulate Drug Delivery Systems sets a solid foundation for new research leading to the discovery and development of better nanomedicines.