A Laboratory Guide to the Tight Junction

A Laboratory Guide to the Tight Junction
Author: Jianghui Hou
Publsiher: Academic Press
Total Pages: 420
Release: 2020-04-24
ISBN 10: 0128226439
ISBN 13: 9780128226438
Language: EN, FR, DE, ES & NL

A Laboratory Guide to the Tight Junction Book Review:

A Laboratory Guide to the Tight Junction offers broad coverage of the unique methods required to investigate its characteristics. The methods are described in detail, including its biochemical and biophysical principles, step-by-step process, data analysis, troubleshooting, and optimization. The coverage includes various cell, tissue, and animal models. Chapter 1 provides the foundations of cell biology of tight junction. Chapter 2 covers the Biochemical approaches for paracellular channels and is followed by chapter 3 providing the Biophysical approaches. Chapter 4 describes and discusses Histological approaches for tissue fixation and preparation. Chapter 5 discusses Light microscopy, while chapter 6 presents Electron microscopic approaches. Chapter 7 covers Transgenic manipulation in cell cultures, including DNA and siRNA, Mutagenesis, and viral infection. Chapter 8 covers transgenic manipulation in mice, including: Knockout, Knockin, siRNA knockdown, GFP/LacZ reporter, and overexpression. The final chapter discusses the future developments of new approaches for tight junction research. Researchers and advanced students in bioscience working on topics of cell junction, ion channel and membrane protein will benefit from the described methods. Clinicians and pathologists interested in tissue barrier diseases will also benefit from the biochemical and biophysical characterization of tight junctions in organ systems, and their connection to human diseases. Provides consistent and detailed research methods Covers various cell, tissue and animal models Includes step-by-step guidance from beginner to sophisticated levels

A Laboratory Guide to Human Physiology

A Laboratory Guide to Human Physiology
Author: Stuart Ira Fox
Publsiher: Unknown
Total Pages: 323
Release: 1984
ISBN 10: 9780697047243
ISBN 13: 0697047245
Language: EN, FR, DE, ES & NL

A Laboratory Guide to Human Physiology Book Review:

A Laboratory Guide to the Mammalian Embryo

A Laboratory Guide to the Mammalian Embryo
Author: David K. Gardner,Michelle Lane,Andrew J. Watson
Publsiher: Oxford University Press
Total Pages: 394
Release: 2004-01-08
ISBN 10: 9780195142266
ISBN 13: 0195142268
Language: EN, FR, DE, ES & NL

A Laboratory Guide to the Mammalian Embryo Book Review:

Never before has there been such a comprehensive book of protocols. This compendium offers a full range of research techniques-from cell culture, to biochemical, to microscopic and genetic. More focused books, like Cold Spring Harbor's Manipulating the Mouse Embryo, are similar though more narrow in scope. This book will appeal to a broad range of researchers, from basic experimental scientists to clinical and animal scientists.

Claudins

Claudins
Author: Kursad Turksen
Publsiher: Humana Press
Total Pages: 447
Release: 2011-07-02
ISBN 10: 9781617791840
ISBN 13: 1617791849
Language: EN, FR, DE, ES & NL

Claudins Book Review:

Since the initial discovery of the claudins, the field of tight junctions and cell polarity has become increasingly energized, mainly due to the fact that the claudins have provided an opportunity to understand the molecular basis of the tight junction function and their tissue specific roles. In Claudins: Methods and Protocols, experts and pioneers in the field provide an extensive collection of techniques involving these tight junction proteins. Written in the highly successful Methods in Molecular BiologyTM series format, chapters include brief introductions to their respective topics, detailed lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Claudins: Methods and Protocols serves as an ideal guide for all scientists seeking to further our understanding of this vital area of research.

The Paracellular Channel

The Paracellular Channel
Author: Jianghui Hou
Publsiher: Academic Press
Total Pages: 248
Release: 2018-06-08
ISBN 10: 0128146362
ISBN 13: 9780128146361
Language: EN, FR, DE, ES & NL

The Paracellular Channel Book Review:

The Paracellular Channel: Biology, Physiology and Disease serves as the first volume to offer a cohesive and unifying picture of the critical functions of paracellular channels (tight junctions) in different tissues. This new class of ion channel utilizes a completely different mechanism to create ion passage pathways across the cell junction. This volume outlines common principles that govern the organization and regulation of these diverse cellular structures, describes the methodology of study, and highlights the pathophysiologic consequence of abnormal structure and functions of the paracellular channels in human diseases. Coverage includes biochemical, biophysical, structural, physiologic analyses of the paracellular channel, and new technologies for recording and characterization. Offers integrated coverage of all key aspects of the paracellular channel, an understudied field that may hold key insights into some of the most mysterious aspects of physiology Targets different levels of expertise, spanning from graduate students, interns and clinical fellows, to seasoned researchers that study functions, regulation and dysfunctions of different tissue barriers Provides a cohesive and unifying picture that describes the critical functions of paracellular channels (tight junctions) in different tissues

A Practical Guide to Basic Laboratory Andrology

A Practical Guide to Basic Laboratory Andrology
Author: Lars Björndahl,David Mortimer,Christopher L. R. Barratt,Jose Antonio Castilla,Roelof Menkveld,Ulrik Kvist,Juan G. Alvarez,Trine B. Haugen
Publsiher: Cambridge University Press
Total Pages: 135
Release: 2010-04-01
ISBN 10: 1139482491
ISBN 13: 9781139482493
Language: EN, FR, DE, ES & NL

A Practical Guide to Basic Laboratory Andrology Book Review:

This practical, extensively illustrated handbook covers the procedures that are undertaken in andrology and ART laboratories to analyse and assess male-factor infertility, and to prepare spermatozoa for use in assisted conception therapy. The content is presented as brief, authoritative overviews of the relevant biological background for each area, plus detailed, step-by-step descriptions of the relevant analytical procedures. Each technical section includes pertinent quality control considerations, as well as the optimum presentation of results. In addition to the comprehensive 'basic' semen analysis, incorporating careful analysis of sperm morphology, the handbook provides established techniques for the use of computer-aided sperm analysis and sperm functional assessment. Throughout the handbook the interpretation of laboratory results in the clinical context is highlighted, and safe laboratory practice is emphasized. It is an invaluable resource to all scientists and technicians who perform diagnostic testing for male-factor infertility.

A Practical Guide to Basic Laboratory Andrology

A Practical Guide to Basic Laboratory Andrology
Author: David Mortimer,Lars Björndahl,C. L. R. Barratt,José Antonio Castilla,Roelof Menkveld,Ulrik Kvist,Juan G. Alvarez,Trine B. Haugen
Publsiher: Cambridge University Press
Total Pages: 135
Release: 2022-02-28
ISBN 10: 1009181637
ISBN 13: 9781009181631
Language: EN, FR, DE, ES & NL

A Practical Guide to Basic Laboratory Andrology Book Review:

This practical, extensively illustrated handbook covers the procedures that are undertaken in andrology and ART laboratories to analyse and assess male-factor infertility, and to prepare spermatozoa for use in assisted conception therapy. The content is presented as brief, authoritative overviews of the relevant biological background for each area, plus detailed, step-by-step descriptions of the relevant analytical procedures. Each technical section includes quality control considerations and the optimum presentation of results. In addition to the comprehensive 'basic' semen analysis, incorporating careful analysis of sperm morphology, the handbook provides established techniques for the use of computer-aided sperm analysis and sperm functional assessment. The interpretation of laboratory results in the clinical context is highlighted throughout, and safe laboratory practice is emphasized. Fully revised, incorporating the new ISO TS 23162 on basic human semen analysis throughout, this is an invaluable resource to all scientists and technicians who perform diagnostic testing for male-factor infertility.

Physician s Guide to the Laboratory Diagnosis of Metabolic Diseases

Physician   s Guide to the Laboratory Diagnosis of Metabolic Diseases
Author: N. Blau,M. Duran,M.E. Blaskovics,K.M. Gibson
Publsiher: Springer Science & Business Media
Total Pages: 716
Release: 2012-12-06
ISBN 10: 364255878X
ISBN 13: 9783642558788
Language: EN, FR, DE, ES & NL

Physician s Guide to the Laboratory Diagnosis of Metabolic Diseases Book Review:

This second edition of The Physician's Guide provides paediatricians and other physicians with a unique aid to help them select the correct diagnosis from a bewildering array of complex clinical and laboratory data. Delay and mistakes in the diagnosis of inherited metabolic diseases may have devastating consequences. The guide, which includes a CD-ROM, describes 298 disorders which have been grouped into 35 chapters according to the type of condition. Within each group of disorders, chapters provide tables of pertinent clinical findings as well as reference and pathological values for crucial metabolites. Relevant metabolic pathways and diagnostic flow charts are included. There are three indices to make the book as user-friendly as possible.

Human Stem Cell Manual

Human Stem Cell Manual
Author: Suzanne Peterson,Jeanne F. Loring,Robin L. Wesselschmidt,Philip H. Schwartz
Publsiher: Elsevier
Total Pages: 488
Release: 2011-10-10
ISBN 10: 0080549888
ISBN 13: 9780080549880
Language: EN, FR, DE, ES & NL

Human Stem Cell Manual Book Review:

Stem cells are self-replicating and undifferentiated, meaning their function is not yet cell, tissue, or organ-specific. Due to the unique nature of these cells, research into their biology and function holds great promise for therapeutic applications through replacement or repair of diseased and damaged cells. This reader-friendly manual provides a practical "hands on" guide to the culture of human embryonic and somatic stem cells. By presenting methods for embryonic and adult lines side-by-side, the authors lay out an elegant and unique path to understanding the science of stem cell practice. The authors begin with a broad-based introduction to the field, and also review legal and regulatory issues and patents. Each experimental strategy is presented with an historical introduction, detailed method, discussion of alternative methods, and common pitfalls. This lab guide for researchers also serves as a textbook for undergraduate and graduate students in laboratory courses.

Oral Histology Laboratory Guide

Oral Histology Laboratory Guide
Author: Anonim
Publsiher: Unknown
Total Pages: 73
Release: 1978
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015060286641
Language: EN, FR, DE, ES & NL

Oral Histology Laboratory Guide Book Review:

The Impact of Food Bioactives on Health

The Impact of Food Bioactives on Health
Author: Kitty Verhoeckx,Paul Cotter,Iván López-Expósito,Charlotte Kleiveland,Tor Lea,Alan Mackie,Teresa Requena,Dominika Swiatecka,Harry Wichers
Publsiher: Springer
Total Pages: 338
Release: 2015-04-29
ISBN 10: 3319161040
ISBN 13: 9783319161044
Language: EN, FR, DE, ES & NL

The Impact of Food Bioactives on Health Book Review:

“Infogest” (Improving Health Properties of Food by Sharing our Knowledge on the Digestive Process) is an EU COST action/network in the domain of Food and Agriculture that will last for 4 years from April 4, 2011. Infogest aims at building an open international network of institutes undertaking multidisciplinary basic research on food digestion gathering scientists from different origins (food scientists, gut physiologists, nutritionists...). The network gathers 70 partners from academia, corresponding to a total of 29 countries. The three main scientific goals are: Identify the beneficial food components released in the gut during digestion; Support the effect of beneficial food components on human health; Promote harmonization of currently used digestion models Infogest meetings highlighted the need for a publication that would provide researchers with an insight into the advantages and disadvantages associated with the use of respective in vitro and ex vivo assays to evaluate the effects of foods and food bioactives on health. Such assays are particularly important in situations where a large number of foods/bioactives need to be screened rapidly and in a cost effective manner in order to ultimately identify lead foods/bioactives that can be the subject of in vivo assays. The book is an asset to researchers wishing to study the health benefits of their foods and food bioactives of interest and highlights which in vitro/ex vivo assays are of greatest relevance to their goals, what sort of outputs/data can be generated and, as noted above, highlight the strengths and weaknesses of the various assays. It is also an important resource for undergraduate students in the ‘food and health’ arena.

Skin Barrier Function

Skin Barrier Function
Author: T. Agner
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 164
Release: 2016-02-04
ISBN 10: 3318055867
ISBN 13: 9783318055863
Language: EN, FR, DE, ES & NL

Skin Barrier Function Book Review:

Although a very fragile structure, the skin barrier is probably one of the most important organs of the body. Inward/out it is responsible for body integrity and outward/in for keeping microbes, chemicals, and allergens from penetrating the skin. Since the role of barrier integrity in atopic dermatitis and the relationship to filaggrin mutations was discovered a decade ago, research focus has been on the skin barrier, and numerous new publications have become available. This book is an interdisciplinary update offering a wide range of information on the subject. It covers new basic research on skin markers, including results on filaggrin and on methods for the assessment of the barrier function. Biological variation and aspects of skin barrier function restoration are discussed as well. Further sections are dedicated to clinical implications of skin barrier integrity, factors influencing the penetration of the skin, influence of wet work, and guidance for prevention and saving the barrier. Distinguished researchers have contributed to this book, providing a comprehensive and thorough overview of the skin barrier function. Researchers in the field, dermatologists, occupational physicians, and related industry will find this publication an essential source of information.

Human Neuroanatomy

Human Neuroanatomy
Author: J. Edward Bruni,Donald G. Montemurro
Publsiher: Oxford University Press, USA
Total Pages: 342
Release: 2009
ISBN 10: 0195371429
ISBN 13: 9780195371420
Language: EN, FR, DE, ES & NL

Human Neuroanatomy Book Review:

The Human Brain in Dissection will significantly update the previous edition published in 1988. The last 20 years have sen a significant shift in the way that neuroanatomy is taught in both undergraduate and graduate neuroscience courses, as well as doctorate courses: not only has the time allocated for these courses been reduced, but the methodologies for teaching have become more focused and specific due to these time constraints. The Human Brain in Dissection, Third Edition will provide detailed features of the human brain with the above limitations in mind. 50 new plates will be added to the existing 123 in order to permit the student to see all salient structures and to visualize microscopic structures of the brain stem and spinal cord. Each chapter will cover a specific are of the human brain in such a way that each chapter can be taught in one two-hour neuroanatomy course. New to this edition is the inclusion of a section in each chapter on clinically relevant examples. Each chapter will also include a specific laboratory exercise. And finally, the author has included a question and answer section that is relevant to the USMLE, as as recommended readings, neither of which were included in the previous editions. This new edition of The Human Brain in Dissection will allow the student to: understand basic principles of cellular neuroscience; learn gross and microscopic anatomy of the central nervous system (Brain, brainstem, and spinal cord); relate the anatomy of central neural pathways to specific functional systems; be able to localize and name a CNS legion when presented with neurological symptoms, and appreciate higher cortical functions and how they relate to the practice of neurology. neuroscience

NIH Guide for Grants and Contracts

NIH Guide for Grants and Contracts
Author: National Institutes of Health (U.S.)
Publsiher: Unknown
Total Pages: 135
Release: 2022
ISBN 10: 1928374650XXX
ISBN 13: STANFORD:36105219414625
Language: EN, FR, DE, ES & NL

NIH Guide for Grants and Contracts Book Review:

General Zoology Laboratory Guide

General Zoology Laboratory Guide
Author: Charles F. Lytle,John R. Meyer
Publsiher: McGraw-Hill Science, Engineering & Mathematics
Total Pages: 372
Release: 2004-02-28
ISBN 10: 9780072349009
ISBN 13: 007234900X
Language: EN, FR, DE, ES & NL

General Zoology Laboratory Guide Book Review:

General Zoology Laboratory Manual is ideal for the laboratory that emphasizes the dissection and microscopic study of live and preserved specimens. Recognized for its accuracy and readability, this manual is comprehensive in its representation of the major groups of animal phyla.This new edition is suitable for a wide range of course needs and structures.

A Comprehensive Guide to Toxicology in Nonclinical Drug Development

A Comprehensive Guide to Toxicology in Nonclinical Drug Development
Author: Ali S. Faqi
Publsiher: Academic Press
Total Pages: 986
Release: 2016-11-03
ISBN 10: 0128036214
ISBN 13: 9780128036211
Language: EN, FR, DE, ES & NL

A Comprehensive Guide to Toxicology in Nonclinical Drug Development Book Review:

A Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology

The Laboratory Guide

The Laboratory Guide
Author: Sir Arthur Herbert CHURCH
Publsiher: Unknown
Total Pages: 292
Release: 1894
ISBN 10: 1928374650XXX
ISBN 13: WISC:89043723543
Language: EN, FR, DE, ES & NL

The Laboratory Guide Book Review:

A Practical Guide to the Histology of the Mouse

A Practical Guide to the Histology of the Mouse
Author: Cheryl L. Scudamore
Publsiher: John Wiley & Sons
Total Pages: 248
Release: 2013-12-24
ISBN 10: 1118789474
ISBN 13: 9781118789476
Language: EN, FR, DE, ES & NL

A Practical Guide to the Histology of the Mouse Book Review:

A Practical Guide to the Histology of the Mouse provides a full-colour atlas of mouse histology. Mouse models of disease are used extensively in biomedical research with many hundreds of new models being generated each year. Complete phenotypic analysis of all of these models can benefit from histologic review of the tissues. This book is aimed at veterinary and medical pathologists who are unfamiliar with mouse tissues and scientists who wish to evaluate their own mouse models. It provides practical guidance on the collection, sampling and analysis of mouse tissue samples in order to maximize the information that can be gained from these tissues. As well as illustrating the normal microscopic anatomy of the mouse, the book also describes and explains the common anatomic variations, artefacts associated with tissue collection and background lesions to help the scientist to distinguish these changes from experimentally- induced lesions. This will be an essential bench-side companion for researchers and practitioners looking for an accessible and well-illustrated guide to mouse pathology. Written by experienced pathologists and specifically tailored to the needs of scientists and histologists Full colour throughout Provides advice on sampling tissues, necropsy and recording data Includes common anatomic variations, background lesions and artefacts which will help non-experts understand whether histologic variations seen are part of the normal background or related to their experimental manipulation

Molecular Biology of the Cell

Molecular Biology of the Cell
Author: Bruce Alberts
Publsiher: Unknown
Total Pages: 135
Release: 2004
ISBN 10: 9780815332183
ISBN 13: 0815332181
Language: EN, FR, DE, ES & NL

Molecular Biology of the Cell Book Review:

The Laboratory Mouse

The Laboratory Mouse
Author: Hans J. Hedrich
Publsiher: Academic Press
Total Pages: 845
Release: 2012
ISBN 10: 0123820081
ISBN 13: 9780123820082
Language: EN, FR, DE, ES & NL

The Laboratory Mouse Book Review:

The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries