Green Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles
Author: Goutam Brahmachari
Publsiher: Elsevier
Total Pages: 646
Release: 2021-03-20
ISBN 10: 0323851304
ISBN 13: 9780323851305
Language: EN, FR, DE, ES & NL

Green Synthetic Approaches for Biologically Relevant Heterocycles Book Review:

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability

Green Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles
Author: Goutam Brahmachari
Publsiher: Elsevier
Total Pages: 822
Release: 2021-02-26
ISBN 10: 0323851339
ISBN 13: 9780323851336
Language: EN, FR, DE, ES & NL

Green Synthetic Approaches for Biologically Relevant Heterocycles Book Review:

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field with an emphasis on sustainability Highlights a range of different eco-friendly solvents and environmentally-friendly catalysts Collates the experience of a global team of expert contributors

Green Synthetic Processes and Procedures

Green Synthetic Processes and Procedures
Author: Roberto Ballini
Publsiher: Royal Society of Chemistry
Total Pages: 404
Release: 2019-06-28
ISBN 10: 1788015126
ISBN 13: 9781788015127
Language: EN, FR, DE, ES & NL

Green Synthetic Processes and Procedures Book Review:

The principles of Green Chemistry aim to improve the sustainability of chemical processes and reduce the generation of hazardous substances. There has been great growth in the field over the past few years and the number of research groups working in this area is still increasing. Now one of the biggest challenges is to embed the Green Chemistry ideals of safety and sustainability as standard, both in industry and academia. In order to do this, it is important to create resources that detail different applications and approaches. Green Synthetic Processes and Procedures brings together expert contributors from across a number of areas of green synthesis to cover a diverse array of subjects. Providing a thorough overview of the current green synthetic toolbox, from biocatalysis to sonochemistry, this book is a useful resource for any chemist wishing to design cleaner and safer processes.

Green Chemistry Synthesis of Bioactive Heterocycles

Green Chemistry  Synthesis of Bioactive Heterocycles
Author: K. L. Ameta,Anshu Dandia
Publsiher: Springer
Total Pages: 412
Release: 2014-06-17
ISBN 10: 8132218507
ISBN 13: 9788132218500
Language: EN, FR, DE, ES & NL

Green Chemistry Synthesis of Bioactive Heterocycles Book Review:

The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.

Green Synthesis of Heterocycles

Green Synthesis of Heterocycles
Author: Fabio Arico,Oliver Reiser
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-03-09
ISBN 10: 2889635848
ISBN 13: 9782889635849
Language: EN, FR, DE, ES & NL

Green Synthesis of Heterocycles Book Review:

Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Green Approaches in Medicinal Chemistry for Sustainable Drug Design
Author: Bimal K. Banik
Publsiher: Elsevier
Total Pages: 1044
Release: 2020-03-27
ISBN 10: 0128175931
ISBN 13: 9780128175934
Language: EN, FR, DE, ES & NL

Green Approaches in Medicinal Chemistry for Sustainable Drug Design Book Review:

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6. Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability Reflects on techniques for a broad range of compounds and materials Highlights sustainable and green chemistry pathways for molecular synthesis

Modern Green Chemistry and Heterocyclic Compounds

Modern Green Chemistry and Heterocyclic Compounds
Author: Ravindra S. Shinde,A. K. Haghi
Publsiher: CRC Press
Total Pages: 302
Release: 2020-03-31
ISBN 10: 1000029174
ISBN 13: 9781000029178
Language: EN, FR, DE, ES & NL

Modern Green Chemistry and Heterocyclic Compounds Book Review:

This book covers the general properties of heterocyclic compounds and methods for their preparation to use in applications of green chemistry. Heterocyclic compounds are an important class of molecules in organic chemistry due to their presence in natural products and their use in pharmaceuticals and new materials. They also play a vital role in the metabolism of living cells. Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products, etc. This research-oriented volume is ideal for readers who want to fully realize the almost limitless potential of heterocyclic compounds and to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features several case studies and step-by-step descriptions of synthetic methods and practical techniques. It also serves as a guide for chemists, offering them new insights and new paths to explore for effective drug discovery.

Room Temperature Organic Synthesis

Room Temperature Organic Synthesis
Author: Goutam Brahmachari
Publsiher: Elsevier
Total Pages: 386
Release: 2015-03-19
ISBN 10: 0128011386
ISBN 13: 9780128011386
Language: EN, FR, DE, ES & NL

Room Temperature Organic Synthesis Book Review:

Filling a gap in the scientific literature, Room Temperature Organic Synthesis is unique in its authoritative, thorough, and applied coverage of a wide variety of "green" organic synthetic methodologies. The book describes practical, feasible protocols for room temperature reactions to produce carbon-carbon and carbon-heteroatom bond formations including aliphatic, aromatic, alicyclic, heterocycles, and more. Consistently organized for easy access, each selected reaction is discussed in a very compact and structured manner including: reaction type, reaction condition, reaction strategy, catalyst, keywords, general reaction scheme, mechanism (in selected cases), representative entries, experimental procedure, characterization data of representative entries, and references. This book will be a valuable resource for synthetic organic, natural products, medicinal, and biochemists as well as those working in the pharmaceutical and agrochemical industry. Includes more than 300 protocols for a green approach to organic synthesis Provides specific detail about experimental conditions Increases efficiency in the laboratory by eliminating time-consuming literature searches

Modern Strategies for Heterocycle Synthesis

Modern Strategies for Heterocycle Synthesis
Author: Gianfranco Favi
Publsiher: MDPI
Total Pages: 372
Release: 2021-03-17
ISBN 10: 3036503404
ISBN 13: 9783036503400
Language: EN, FR, DE, ES & NL

Modern Strategies for Heterocycle Synthesis Book Review:

Heterocycles feature widely in natural products, agrochemicals, pharmaceuticals and dyes, and their synthesis is of great interest to synthetic chemists in both academia and industry. The contributions of recent applications of new methodologies in C–H activation, photoredox chemistry, cross-coupling strategies, borrowing hydrogen catalysis, multicomponent and solvent-free reactions, regio- and stereoselective syntheses, as well as other new, attractive approaches for the construction of heterocyclic scaffolds are of great interest. This Special Issue is dedicated to featuring the latest research that is ongoing in the field of heterocyclic synthesis. It is expected that most submissions will focus on five- and six-membered oxygen and nitrogen-containing heterocycles, but structures incorporating other rings/heteroatoms will also be considered. Original research (communications, full papers and reviews) that discusses innovative methodologies for assembling heterocycles with potential application in materials, catalysis and medicine are therefore welcome.

Catalyst free Organic Synthesis

Catalyst free Organic Synthesis
Author: Goutam Brahmachari
Publsiher: Royal Society of Chemistry
Total Pages: 392
Release: 2017-11-06
ISBN 10: 1788013182
ISBN 13: 9781788013185
Language: EN, FR, DE, ES & NL

Catalyst free Organic Synthesis Book Review:

It is well-established that organic synthetic processes have been at the core of the chemical industry for hundreds of years, in the production of organic compounds with a wide range of applications. However, we are becoming increasingly aware of the hazardous substances used and generated by these chemical processes. The field of organic synthesis has undergone profound changes to switch to equally efficient, but more sustainable processes that avoid the extensive use of toxic and hazardous reagents and solvents, harsh reaction conditions and expensive and sophisticated catalysts. Explaining methods for carrying out chemical syntheses without the use of catalysts, this book shows how avoiding catalysts during synthesis can mean less use of toxic chemicals, environmentally damaging chemicals or endangered elements and lower costs. It is an important reference for chemists involved in organic synthesis, as well as for green chemists.

Multicomponent Reactions

Multicomponent Reactions
Author: K.L. Ameta, Ph.D.,Anshu Dandia
Publsiher: CRC Press
Total Pages: 394
Release: 2017-09-20
ISBN 10: 1315352737
ISBN 13: 9781315352732
Language: EN, FR, DE, ES & NL

Multicomponent Reactions Book Review:

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.

Green Chemistry and Sustainable Technology

Green Chemistry and Sustainable Technology
Author: Satish A. Dake,Ravindra S. Shinde,Suresh C. Ameta,A. K. Haghi
Publsiher: CRC Press
Total Pages: 318
Release: 2020-08-23
ISBN 10: 1000711293
ISBN 13: 9781000711295
Language: EN, FR, DE, ES & NL

Green Chemistry and Sustainable Technology Book Review:

Taking an interdisciplinary approach, this new volume brings together innovative research, new concepts, and novel developments in the application of new tools in green chemistry and sustainable technology. The diverse coverage includes chapters on ionic liquids as green solvents, an environmentally friendly approach to the synthesis and biological evaluation of α-aminophosphonate derivatives, the application of nanotechnology in biological sciences and green chemistry, eco-friendly polymers, the effect of global warming and greenhouse gases on environmental system, and more.

Bioactive Natural Products

Bioactive Natural Products
Author: Goutam Brahmachari
Publsiher: John Wiley & Sons
Total Pages: 544
Release: 2015-03-23
ISBN 10: 3527337946
ISBN 13: 9783527337941
Language: EN, FR, DE, ES & NL

Bioactive Natural Products Book Review:

Natural compounds, which have evolved their function over millions of years, are often more efficient than man-made compounds if a specific biological activity is needed, e.g. as an enzyme inhibitor or as a toxin to kill a cancer cell. This book comprising of sixteen technical chapters, highlights the chemical and biological aspects of potential natural products with an intention of unravelling their pharmaceutical applicability in modern drug discovery processes. Key features: Covers the synthesis, semi-synthesis and also biosynthesis of potentially bioactive natural products Features chemical and biological advances in naturally occurring organic compounds describing their chemical transformations, mode of actions, and structure-activity relationships 40 expert scientists from around the world report their latest findings and outline future opportunities for the development of novel and highly potent drugs based on natural products operating at the interface of chemistry and biology Forward-looking: Addresses opportunities and cutting-edge developments rather than well-documented basic knowledge, pinpoints current trends and future directions in this rapidly-evolving field Application-oriented: Throughout the book, the focus is on actual and potential applications in pharmacology and biotechnology This book is an essential resource for natural products chemists, medicinal chemists, biotechnologists, biochemists, pharmacologists, as well as the pharmaceutical and biotechnological industries.

Quinoxalines

Quinoxalines
Author: Vakhid A. Mamedov
Publsiher: Springer
Total Pages: 437
Release: 2016-04-26
ISBN 10: 3319297732
ISBN 13: 9783319297736
Language: EN, FR, DE, ES & NL

Quinoxalines Book Review:

This book reviews the fundamental aspects of quinoxaline chemistry: synthesis, reactions, mechanisms, structure, properties, and uses. The first four chapters present a survey of the developments in quinoxaline chemistry since the publication of the monograph on “Condensed Pyrazines” by Cheeseman and Cookson in 1979. These chapters give comprehensive coverage of all the methods of the synthesis of quinoxalines and the important quinoxaline-containing ring systems such as thiazolo[3,4-a]-, pyrrolo[1,2-a]-, and imidazo[1,5-a]quinoxalines. Chapter five describes many new methods for the construction of quinoxaline macrocycles, which are important in applications such as optical devices and materials. The final chapter reviews all previously known rearrangements of heterocyclic systems that lead to benzimidazole derivatives. Mamedov critically analyses these transformations to reveal a novel acid-catalyzed rearrangement of quinoxalinones giving 2-heteroarylbenzimidazoles and 1-heteroarylbenzimidazolones in the presence of nucleophilic reactants (MAMEDOV Heterocycle Rearrangement). This book is of interest to researchers in the fields of heterocyclic and synthetic organic chemistry.

Flow Chemistry in Drug Discovery

Flow Chemistry in Drug Discovery
Author: Jesus Alcazar
Publsiher: Springer Nature
Total Pages: 135
Release: 2022
ISBN 10: 3030855929
ISBN 13: 9783030855925
Language: EN, FR, DE, ES & NL

Flow Chemistry in Drug Discovery Book Review:

Strategies for Organic Drug Synthesis and Design

Strategies for Organic Drug Synthesis and Design
Author: Daniel Lednicer
Publsiher: John Wiley & Sons
Total Pages: 700
Release: 2009-03-04
ISBN 10: 9780470399590
ISBN 13: 0470399597
Language: EN, FR, DE, ES & NL

Strategies for Organic Drug Synthesis and Design Book Review:

This book examines and evaluates the strategies utilized to design and synthesize pharmaceutically active agents. Significant updates over the last 10 years since the publication of the 1st edition include synthesis of enantiomerically pure isomers, novel chemical methodologies, and new pharmaceutical agents targeted at novel biological endpoints. Written by an experienced successful author, this book meets the needs of a growing community of researchers in pharmaceutical R &D, as well as medical professionals, by providing a useful guide for designing and synthesizing pharmaceutical agents. Additionally, it is a useful text for medicinal chemistry students.

Advances in Microwave Chemistry

Advances in Microwave Chemistry
Author: Bimal K Banik,Debasish Bandyopadhyay
Publsiher: CRC Press
Total Pages: 522
Release: 2018-12-07
ISBN 10: 135124048X
ISBN 13: 9781351240482
Language: EN, FR, DE, ES & NL

Advances in Microwave Chemistry Book Review:

Advances in Microwave Chemistry discusses the novel bond formation methodologies, synergistic effects of microwaves with other entities, sample preparation including digestion, combustion, and extraction techniques, as well as selectivity in chemical processes. Recent updates are provided on microwave-assisted syntheses of pharmacologically significant aza-, oxo- and other heterocycles, including lactams, nucleosides, bile acids and sterols, the preparation of nanomaterials, composites, and absorber layer materials for thin film. This book also incorporates comparative discussions involving microwave irradiation with conventional methods in different aspects of organic, inorganic, medicinal, and green chemistry. Key Features: Provides a comparative discussion on microwave irradiation with conventional methods in different aspects of organic, inorganic, medicinal, and green chemistry Presents recent applications of microwave radiation in biocatalysis Offers a complete package correlating various aspects of microwaves in organic syntheses, the biological impact of products formed in reactions, pharmacological features, and environmental sustainability of the procedures Explains microwave-induced reactions on structurally complex bile acids and sterols Stands as a valuable and unique addition to the well-established book series, New Directions in Organic and Biological Chemistry

Heterocyclic Scaffolds I

Heterocyclic Scaffolds I
Author: Bimal K. Banik
Publsiher: Springer
Total Pages: 379
Release: 2010-06-01
ISBN 10: 3642128459
ISBN 13: 9783642128455
Language: EN, FR, DE, ES & NL

Heterocyclic Scaffolds I Book Review:

Contents: B. Alcaide ∙ P. Almendros: Novel Aspects on the Preparation of Spirocyclic and Fused Unsual β-Lactams.- S.S. Bari ∙ A. Bhalla: Spirocyclic β-Lactams: Synthesis and Biological Evaluation of Novel Heterocycles.- L. Troisi ∙ C. Granito ∙ E. Pindinelli: Novel and Recent Synthesis and Applications of β-Lactams.- C. Palomo ∙ M. Oiarbide: β-Lactams Ring Opening: A Useful Entry to Amino Acids and Relevant Nitrogen-Containing Compounds.- B. Mandal ∙ P. Ghosh ∙ B. Basu: Recent Approaches Towards Solid Phase Synthesis of β-Lactams.- A.Arrieta ∙ B. Lecea ∙ F.P. Cossio: Computational Studies on the Synthesis of β-Lactams Via [ 2+2] Thermal Cycloadditions.- B. K. Banik ∙ I. Banik ∙ F. F. Becker: Novel Anticancer β-Lactams

Organophosphorus Chemistry

Organophosphorus Chemistry
Author: Viktor Iaroshenko
Publsiher: John Wiley & Sons
Total Pages: 224
Release: 2019-01-07
ISBN 10: 3527672257
ISBN 13: 9783527672257
Language: EN, FR, DE, ES & NL

Organophosphorus Chemistry Book Review:

Filling the gap for an up-to-date reference that presents the field of organophosphorus chemistry in a comprehensive and clearly structured way, this one-stop source covers the chemistry, properties, and applications from life science and medicine. Divided into two parts, the first presents the chemistry of various phosphorus-containing compounds and their synthesis, including ylides, acids, and heterocycles. The second part then goes on to look at applications in life science and bioorganic chemistry. Last but not least, such important practical aspects as 31P-NMR and protecting strategies for these compounds are presented. For organic, bioinorganic, and medicinal chemists, as well as those working on organometallics, and for materials scientists. The book, a contributed work, features a team of renowned scientists from around the world whose expertise spans the many aspects of modern organophosphorus chemistry.

Recent Trends in Carbohydrate Chemistry

Recent Trends in Carbohydrate Chemistry
Author: Amélia Pilar Rauter,Björn Christensen,Laszlo Somsak,Roberto Adamo,Paul Kosma
Publsiher: Unknown
Total Pages: 532
Release: 2020-04-24
ISBN 10: 0128174676
ISBN 13: 9780128174678
Language: EN, FR, DE, ES & NL

Recent Trends in Carbohydrate Chemistry Book Review:

Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry.