Resistance to Immunotherapeutic Antibodies in Cancer

Resistance to Immunotherapeutic Antibodies in Cancer
Author: Benjamin Bonavida
Publsiher: Springer Science & Business Media
Total Pages: 202
Release: 2013-08-04
ISBN 10: 1461476542
ISBN 13: 9781461476542
Language: EN, FR, DE, ES & NL

Resistance to Immunotherapeutic Antibodies in Cancer Book Review:

​​​​The traditional approaches to treat various cancers include chemotherapy, radiation and/or hormonal therapy. While these therapies continue to be effective in large part, they are not selective and highly toxic. There have been encouraging results in alternative therapeutic approach called antibody-mediated anti-cancer therapy, which is less toxic, more selective, and can also reverse drug/radiation resistance. Monoclonal antibodies or mAbs can be used to destroy malignant tumor cells and prevent tumor growth by blocking specific cell receptors. mAbs can bind only to cancer cell-specific antigens and induce an immunological response against the target cancer cell. The book covers the common and unique features of mAbs agains various cancer, gives the latest developments on the molecular, biochemical and genetic mechanisms of resistance by various mAbs, as well as discuss novel mAbs to overcome resistance.

Cancer Chemotherapy and Biotherapy

Cancer Chemotherapy and Biotherapy
Author: Bruce A. Chabner,Dan L. Longo
Publsiher: Lippincott Williams & Wilkins
Total Pages: 848
Release: 2011-12-07
ISBN 10: 1451148208
ISBN 13: 9781451148206
Language: EN, FR, DE, ES & NL

Cancer Chemotherapy and Biotherapy Book Review:

Updated to include the newest drugs and those currently in development, this Fifth Edition is a comprehensive reference on the preclinical and clinical pharmacology of anticancer agents. Organized by drug class, the book provides the latest information on all drugs and biological agents—their mechanisms of action, interactions with other agents, toxicities, side effects, and mechanisms of resistance. The authors explain the rationale for use of drugs in specific schedules and combinations and offer guidelines for dose adjustment in particular situations. This edition's introduction includes timely information on general strategies for drug usage, the science of drug discovery and development, economic and regulatory aspects of cancer drug development, and principles of pharmacokinetics. Eight new chapters have been added and more than twenty have been significantly revised. A companion website includes the fully searchable text and an image bank.

Targeted Cancer Therapies, From Small Molecules to Antibodies

Targeted Cancer Therapies, From Small Molecules to Antibodies
Author: Zhe-Sheng Chen,Jian-ye Zhang,Yunkai Zhang,Yan-yan Yan
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2020-07-22
ISBN 10: 2889638847
ISBN 13: 9782889638840
Language: EN, FR, DE, ES & NL

Targeted Cancer Therapies, From Small Molecules to Antibodies Book Review:

Nanostructures for Cancer Therapy

Nanostructures for Cancer Therapy
Author: Alexandru Mihai Grumezescu,Anton Ficai
Publsiher: Elsevier
Total Pages: 920
Release: 2017-04-11
ISBN 10: 0323461506
ISBN 13: 9780323461504
Language: EN, FR, DE, ES & NL

Nanostructures for Cancer Therapy Book Review:

Nanostructures for Cancer Therapy discusses the available preclinical and clinical nanoparticle technology platforms and their impact on cancer therapy, including current trends and developments in the use of nanostructured materials in chemotherapy and chemotherapeutics. In particular, coverage is given to the applications of gold nanoparticles and quantum dots in cancer therapies. In addition to the multifunctional nanomaterials involved in the treatment of cancer, other topics covered include nanocomposites that can target tumoral cells and the release of antitumoral therapeutic agents. The book is an up-to-date overview that covers the inorganic and organic nanostructures involved in the diagnostics and treatment of cancer. Provides an examination of nanoparticle delivery systems for cancer treatment, illustrating how the use of nanotechnology can help provide more effective chemotherapeutic treatments Examines, in detail, the different types of nanomaterials used in cancer therapy, also explaining the effect of each Provides a cogent overview of recent developments in the use of nanostructured materials in chemotherapeutics, allowing readers to quickly familiarize themselves with this area

Breast Cancer Chemosensitivity

Breast Cancer Chemosensitivity
Author: Dihua Yu,Mien-Chie Hung
Publsiher: Springer Science & Business Media
Total Pages: 175
Release: 2009-12-30
ISBN 10: 0387740392
ISBN 13: 9780387740393
Language: EN, FR, DE, ES & NL

Breast Cancer Chemosensitivity Book Review:

In Breast Cancer Chemosensitivity, a group of world leading experts review critical aspects of resistance to systemic therapy in breast cancer patients. Beginning with a clinical overview of the problem, the book then focuses on the latest findings of molecular mechanisms of drug resistance. Coverage provides an example of using novel approaches for chemosensitization of breast cancer cells that gives readers an idea about the future direction in breast cancer treatment. It allows those who are interested in breast cancer therapy to get a jump-start on critical issues in breast cancer therapeutic resistance.

Targeted Therapies in Breast Cancer

Targeted Therapies in Breast Cancer
Author: George W. Sledge, Jr.,Jose Baselga
Publsiher: Anonim
Total Pages: 100
Release: 2013-04-15
ISBN 10: 9781846920660
ISBN 13: 1846920663
Language: EN, FR, DE, ES & NL

Targeted Therapies in Breast Cancer Book Review:

This new volume updates the reader on selected areas of targeted therapy in breast cancer, with special emphasis on chemoprevention strategies, drug resistance, biomarkers, combination chemotherapy, angiogenesis inhibition and pharmacogenomics in the context of clinical efficacy. This selected review of targeted therapies will guide the reader on effective treatment as part of an integrated programme of patient management.

Anticancer Research

Anticancer Research
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2007
ISBN 10:
ISBN 13: UCLA:L0098826472
Language: EN, FR, DE, ES & NL

Anticancer Research Book Review:

Adjuvant Therapy for Breast Cancer

Adjuvant Therapy for Breast Cancer
Author: Monica Castiglione,Martine J. Piccart
Publsiher: Springer Science & Business Media
Total Pages: 490
Release: 2009-07-11
ISBN 10: 9780387751153
ISBN 13: 0387751157
Language: EN, FR, DE, ES & NL

Adjuvant Therapy for Breast Cancer Book Review:

Adjuvant treatment is administered prior to or as follow up to surgical procedures for breast cancer. Proven success in using medical therapies allowing for breast conserving procedures or reducing risk of occurrence. Although there has been much progress towards a cure, including the introduction of new targeted therapies, metastasizing cancer remains highly incurable.

Advances in Cancer Research

Advances in Cancer Research
Author: George F. Vande Woude,George Klein
Publsiher: Academic Press
Total Pages: 160
Release: 2009-10-22
ISBN 10: 0080912265
ISBN 13: 9780080912264
Language: EN, FR, DE, ES & NL

Advances in Cancer Research Book Review:

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including nitric oxide-induced apoptosis in tumor cells, detection of minimal residual disease, immunity to oncogenetic human papillomavirus, and modeling prostate cancer in the mouse.

Difficult Diagnoses in Breast Pathology

Difficult Diagnoses in Breast Pathology
Author: Juan P. Palazzo, MD
Publsiher: Demos Medical Publishing
Total Pages: 264
Release: 2011-06-22
ISBN 10: 1935281305
ISBN 13: 9781935281306
Language: EN, FR, DE, ES & NL

Difficult Diagnoses in Breast Pathology Book Review:

Breast cancer is the second leading cause of cancer death in women in the United States. For the pathologist, almost any breast lesion may produce diagnostic difficulty, especially due to frequently small samples (core biopsy specimens) and a variety of mimics and variants seen in specific types of lesions. Additionally, the difficulty of breast lesion diagnosis has risen dramatically in recent years due to the increased emphasis on stratifying patients for appropriate therapy on an individual basis; the wider range of both local and systemic therapeutic options, and the potential for earlier diagnosis through increased mammographic breast screening leading to a higher likelihood of a favorable outcome. Difficult Diagnoses in Breast Pathology provides a highly visual presentation of the major problems and questions that a pathologist is likely to encounter in the evaluation of common and uncommon breast diseases. Coverage includes needle core biopsy interpretation, diagnosis of precursor lesions, early stage disease, and recognition of neoplastic mimics and other misleading variants. In addition, this book emphasizes particularly difficult areas including the use of newer immunohistochemical markers. Throughout, the emphasis is on an easily accessible presentation with tables and lists of key points summarizing major findings and numerous high-quality images supporting the text. Difficult Diagnoses in Breast Pathology will be a valuable reference for every pathologist who deals with the diagnosis of breast diseases. Difficult Diagnoses in Breast Pathology Features: Each chapter authored by recognized expert in the area Hundreds of high-quality images Tables and key points in each chapter summarize the most important findings Coverage based on addressing in detail the real-world diagnostic problems the pathologist will face in daily practice

Breast Cancer Management

Breast Cancer Management
Author: Lynda R. Wiseman
Publsiher: Lippincott Williams & Wilkins
Total Pages: 133
Release: 2000
ISBN 10:
ISBN 13: UCSD:31822028487379
Language: EN, FR, DE, ES & NL

Breast Cancer Management Book Review:

Cancer Research

Cancer Research
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2009-11
ISBN 10:
ISBN 13: CORNELL:31924108301635
Language: EN, FR, DE, ES & NL

Cancer Research Book Review:

Oncology

Oncology
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2006
ISBN 10:
ISBN 13: UCLA:L0090580473
Language: EN, FR, DE, ES & NL

Oncology Book Review:

Recent Developments in Monoclonal Antibody Therapy for Breast Cancer

Recent Developments in Monoclonal Antibody Therapy for Breast Cancer
Author: Brittany Jiang
Publsiher: Anonim
Total Pages: 56
Release: 2008
ISBN 10:
ISBN 13: UCAL:X79024
Language: EN, FR, DE, ES & NL

Recent Developments in Monoclonal Antibody Therapy for Breast Cancer Book Review:

Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition

Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition
Author: Laurence Brunton,Bjorn Knollman,Randa Hilal-Dandan
Publsiher: McGraw Hill Professional
Total Pages: 1808
Release: 2017-10-26
ISBN 10: 1259584747
ISBN 13: 9781259584749
Language: EN, FR, DE, ES & NL

Goodman and Gilman's The Pharmacological Basis of Therapeutics, 13th Edition Book Review:

The gold-standard of pharmacology texts – completely updated to reflect the latest research and developments A Doody’s Core Title for 2019! Goodman & Gilman’s: The Pharmacological Basis of Therapeutics, Thirteenth Edition represents the pinnacle of authority and accuracy in describing the actions and uses of therapeutic agents in relation to physiology and pathophysiology. Goodman & Gilman’s careful balance of basic science and clinical application has guided thousands of practitioners and students to a clear understanding of the drugs essential to preventing, diagnosing, and treating disease. The Thirteenth Edition includes more than 500 color illustrations, with many new figures emphasizing mechanisms of drug action. More than 30 new contributors have added to this edition, while the focus on basic principles is undiminished. This edition is enhanced by timely new content: •NEW chapters including Treatment of Pulmonary Arterial Hypertension, Immunity and Inflammation, Immunoglobulins and Vaccines, and Treatment of Viral Hepatitis •Expanded coverage of cardiovascular disease, with separate chapters on myocardial ischemia, hypertension, and heart failure •Increased emphasis on cellular signaling pathways involved in drug action •Summary tables at the end of each chapter that organize drugs discussed in that chapter into relevant categories and detail therapeutic usage, clinical pharmacology, and tips •Chapter Content Outlines at the beginning of each chapter •Abbreviation boxes in every chapter to easily identify the abbreviations appearing in that chapter More than a textbook, Goodman & Gilman’s is a working template for the effective and rational prescribing of drugs in daily practice.

Cancer: New Insights for the Healthcare Professional: 2011 Edition

Cancer: New Insights for the Healthcare Professional: 2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 3937
Release: 2012-01-09
ISBN 10: 1464900027
ISBN 13: 9781464900020
Language: EN, FR, DE, ES & NL

Cancer: New Insights for the Healthcare Professional: 2011 Edition Book Review:

Cancer: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

The Journal of Nuclear Medicine

The Journal of Nuclear Medicine
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2008
ISBN 10:
ISBN 13: UCSD:31822034999987
Language: EN, FR, DE, ES & NL

The Journal of Nuclear Medicine Book Review:

Indian Journal of Medical Research

Indian Journal of Medical Research
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2007
ISBN 10:
ISBN 13: UCLA:L0098889900
Language: EN, FR, DE, ES & NL

Indian Journal of Medical Research Book Review:

Tumor Progression and Therapeutic Resistance

Tumor Progression and Therapeutic Resistance
Author: Wafik S. El-Deiry
Publsiher: Anonim
Total Pages: 198
Release: 2005
ISBN 10:
ISBN 13: UVA:X030000978
Language: EN, FR, DE, ES & NL

Tumor Progression and Therapeutic Resistance Book Review:

This volume presents the entire breadth of translational cancer research and brings together members of academia and industry in the expectation of accelerating interactions and progress in the field. A variety of key topics are presented, beginning with discovery of molecular targets and pathways (oncogene, cell survival, tumor suppression, cell death), host-neoplasm interactions (cell adhesion, matrix proteases), early detection, monitoring progression, understanding tumor progression and metastasis, immune surveillance, in vivo molecular imaging, animal models, drug discovery including chemistry, high-throughput assays, mechanism determination, target validation, therapeutic window and some progress in clinical trials for more advanced agents and targets.

The Molecular Basis of Cancer

The Molecular Basis of Cancer
Author: John Mendelsohn,Peter M. Howley,Mark A. Israel,Lance A. Liotta,Joe W. Gray,Craig B. Thompson
Publsiher: W B Saunders Company
Total Pages: 691
Release: 2001
ISBN 10:
ISBN 13: UOM:39015053365188
Language: EN, FR, DE, ES & NL

The Molecular Basis of Cancer Book Review:

The state-of-the-art 2nd Edition of this acclaimed reference explains the principles that form the scientific basis for our understanding of malignant transformation and the pathogenesis and treatment of cancer. Readers will find a broad update on the scientific principles of new diagnostic tests and therapeutic interventions now being used in clinical trials and practice. Incorporating the latest advances and newest research, this text also gives thorough descriptions of everything from the basic mechanisms of malignant cells and molecular abnormalities in common cancers to new approaches for cancer therapy. Each chapter discusses the clinical implications for treatment. Numerous examples of the latest clinical interventions help readers understand and assess the products of the biotechnology revolution. IMPORTANT new topics, including chemo-prevention, programmed cell death (apoptosis), genetic counselling, tumour-specific vaccines, genetic abnormalities in the origin and progression of cancer, monoclonal antibody therapy, and molecular predictors of prognosis and response to treatment NEW and revised chapters, covering new basic science knowledge, new approaches to treatment and keeping all information on the cutting-edge of the specialty ABUNDANT illustrations, most of them new, to clarify and explain difficult concepts.