Osteosarcopenia Bone Muscle and Fat Interactions

Osteosarcopenia  Bone  Muscle and Fat Interactions
Author: Gustavo Duque
Publsiher: Springer Nature
Total Pages: 383
Release: 2019-11-06
ISBN 10: 3030258904
ISBN 13: 9783030258900
Language: EN, FR, DE, ES & NL

Osteosarcopenia Bone Muscle and Fat Interactions Book Review:

This edited work presents the most current evidence on osteosarcopenia from bench to bedside, which is expected to facilitate the understanding of this syndrome and to develop preventive and therapeutic strategies. With our aging population, chronic diseases such as osteoporosis and sarcopenia are becoming highly prevalent. Fortunately, our understanding of the bone and muscle interactions has increased in recent years. This has allowed to the coining of the term osteosarcopenia to describe a syndrome in which these two diseases overlap. This overlap between osteoporosis and sarcopenia has major negative effects not only on our older adults but also on health systems worldwide. Readers will find a highly translational approach that starts with a summary of recent discoveries on stem cells biology, muscle and bone interactions – including the role of local bone and muscle fat – followed by comprehensive reviews on myokines (i.e. myostatin), osteokines (i.e. osteocalcin) and adipokines (i.e. interleukins) as major players and determinants of bone and muscle loss with aging. In addition, the role of sex steroids (i.e. estrogens, androgens), and calciotropic hormones (i.e. parathyroid hormone, vitamin D) in the pathogenesis of this syndrome is also reviewed. Moreover, using practical diagnostic and therapeutic tips, this book summarizes the clinical characteristics of osteosarcopenic patients thus facilitating the diagnosis and treatment of this syndrome in clinical practice. Finally, the book presents the case for the Falls and Fractures Clinic as the optimal model of care for this syndrome, aimed to avoid fragmentation and optimize osteosarcopenia care, and simultaneously prevent falls and fractures in older persons. This book offers relevant information on the mechanisms of osteosarcopenia, and a practical guide on how to identify and treat this geriatric syndrome and its adverse outcomes, which are dramatically affecting our aging population. The work is written by leaders in the field and is especially suited not only to any researcher in the musculoskeletal arena but also to medical specialists and allied health professionals involved in the care of older persons.

Osteosarcopenia

Osteosarcopenia
Author: Gustavo Duque,Bruce R. Troen
Publsiher: Elsevier
Total Pages: 240
Release: 2021-08-15
ISBN 10: 9780128200889
ISBN 13: 012820088X
Language: EN, FR, DE, ES & NL

Osteosarcopenia Book Review:

Falls, fractures, frailty, osteoporosis and sarcopenia are highly prevalent in older persons. While the concept of osteosarcopenia is new, it is a rapidly evolving and cross-disciplinary problem. Prevention and treatment are challenging and a combined therapeutic approach is needed. Osteosarcopenia provides evidence-based information on how to prevent and treat these conditions at multiple settings, including multiple illustrations, care pathways and tips to easily understand the pathophysiology, diagnostic methods and therapeutic approach to these conditions. This work evaluates the potential for a link between osteoporosis, sarcopenia and obesity. Presents diagnostic and therapeutic tips that facilitate the design and implementation of new care pathways,?impacting the wellbeing of our older population Provides cross-disciplinary understanding by experts from the bone/osteoporosis field and the muscle/sarcopenia field Covers muscle and bone biology, mesenchymal stem cells, age-related changes and cross-talk between?muscle, fat and bone, falls and fracture risk, glucose metabolism, diagnosis, imaging, and genetics of?osteosarcopenia

Advances in Clinical Chemistry

Advances in Clinical Chemistry
Author: Gregory S. Makowski
Publsiher: Academic Press
Total Pages: 340
Release: 2020-01-10
ISBN 10: 0128208015
ISBN 13: 9780128208014
Language: EN, FR, DE, ES & NL

Advances in Clinical Chemistry Book Review:

Advances in Clinical Chemistry, Volume 94, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest technologies relating to the field of clinical chemistry, with specific chapters in this new release covering Hypertensive disorders of pregnancy: Strategy to develop clinical peptide biomarkers for more accurate evaluation of the pathophysiological status of this syndrome, Clotting factors - Clinical biochemistry and their roles as plasma enzymes, Myokines: The endocrine coupling of skeletal muscle and bone, Epigenetic reprogramming and potential application of epigenetic-modifying drugs in acquired chemotherapeutic resistance, and more. Provides the most up-to-date technologies in clinical chemistry and clinical laboratory science Authored by world renowned clinical laboratory scientists, physicians and research scientists Presents the international benchmark for novel analytical approaches in the clinical laboratory

Postmenopausal Diseases and Disorders

Postmenopausal Diseases and Disorders
Author: Faustino R. Pérez-López
Publsiher: Springer
Total Pages: 484
Release: 2019-07-10
ISBN 10: 3030139360
ISBN 13: 9783030139360
Language: EN, FR, DE, ES & NL

Postmenopausal Diseases and Disorders Book Review:

Supported by the latest scientific data, this book serves as a guide to the clinical assessment of women’s health during the second half of life (post-reproductive years), including approaches to the management of the most frequent age-related diseases and disorders and the most recent advances in treatment. In addition, it discusses preventive aspects of healthcare in post-reproductive women, identifying lifestyle measures to enhance healthy aging. By highlighting research gaps, it promotes the development of quick and easy-to-use assessment tools and predictive markers of age-related co-morbidities. As such, the book is a valuable resource for researchers and clinicians alike.

Marcus and Feldman s Osteoporosis

Marcus and Feldman s Osteoporosis
Author: David W. Dempster,Jane A. Cauley,Mary L. Bouxsein,Felicia Cosman
Publsiher: Academic Press
Total Pages: 1946
Release: 2020-10-08
ISBN 10: 0128130741
ISBN 13: 9780128130742
Language: EN, FR, DE, ES & NL

Marcus and Feldman s Osteoporosis Book Review:

Marcus and Feldman's Osteoporosis, Fifth Edition, is the most comprehensive, authoritative reference on this disease. Led by a new editorial team, this fifth edition offers critical information on reproductive and hormonal risk factors, new therapeutics, ethnicity, nutrition, therapeutics, management and economics, comprising a tremendous wealth of knowledge in a single source not found elsewhere. Written by renowned experts in the field, this two-volume reference is a must-have for biomedical researchers, research clinicians, fellows, academic and medical libraries, and any company involved in osteoporosis drug research and development. Summarizes the latest research in bone biology and translational applications in a range of new therapeutic agents, including essential updates on therapeutic uses of calcium, vitamin D, SERMS, bisphosphonates, parathyroid hormone, and new therapeutic agents Recognizes the critical importance of new signaling pathways for bone health, including Wnt, OPG and RANK, of interest to both researchers who study bone biology and clinicians who treat osteoporosis Offers new insights into osteoporosis associated with menopause, pre-menopause, chronic kidney disease, diabetes, HIV and other immune disorders

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism
Author: Anonim
Publsiher: John Wiley & Sons
Total Pages: 1136
Release: 2018-12-06
ISBN 10: 1119266564
ISBN 13: 9781119266563
Language: EN, FR, DE, ES & NL

Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism Book Review:

The authoritative reference to bone diseases and disorders of mineral metabolism, revised and updated Now in its ninth edition, The Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism offers an updated and comprehensive guide to bone and mineral health. Since it was first published 30 years ago, the Primer has become the leading reference on the topic. With contributions from noted experts, the text explores basic biological factors of healthy development and disease states and makes the information accessible for clinical interventions. The ninth edition provides concise coverage of the widest possible spectrum of metabolic bone diseases and disorders of mineral metabolism. The new edition of this invaluable reference expands coverage and includes the most recent developments in the field that help to strengthen its usefulness and ensure that the Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism maintains its place as the pre-eminent reference on bone and mineral health. This vital resource: Provides the most accurate, up-to-date evidence-based information on basic and clinical bone science Includes more than 10 new chapters and contributions from 300 authors from wide-ranging international research centers Captures the very cutting edge of research covering mineral homeostasis, osteoporosis and other metabolic bone diseases, skeletal measurement technologies, and genetics Presents a new companion website with useful supplementary materials at www.asbmrprimer.com Written for advanced students, clinicians, and researchers working in the field of bone health and disease, Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism is the definitive, one-stop reference for anyone working in the field of bone health and disease.

Osteoporosis in Older Persons

Osteoporosis in Older Persons
Author: Gustavo Duque,Douglas P. Kiel
Publsiher: Springer
Total Pages: 282
Release: 2016-07-11
ISBN 10: 3319259768
ISBN 13: 9783319259765
Language: EN, FR, DE, ES & NL

Osteoporosis in Older Persons Book Review:

This new edition includes the most up-to-date information about the pathophysiology and new therapeutic alternatives for osteoporosis of advanced age. It is written by investigators (clinicians and basic scientists) in the field of aging bone research. It was just recently that a new syndrome, osteoporosis of advanced age, was recognized as a new entity with its own pathophysiology and potential treatments. Unfortunately, and despite the fact that hip fractures are mostly a consequence of this process, and apart from the first edition of this book, there are few publications about this subject. The first edition of this book demonstrated that there is a need to understand the particular features of osteoporosis in older persons, which is the main aim of this book. The institutions where the authors are affiliated are highly recognized as the main centers in aging bone research. As an innovation, the second edition includes some aspects of muscle and bone interaction focusing of the impact of age-related muscle loss (sarcopenia) on the pathogenesis of falls and fractures in older persons. As in the previous edition, this book is expected to be the reference guide for geriatricians, gerontologists, and bone biologists as well as medical trainees in order to understand the mechanisms of senile osteoporosis with a practical approach to the treatment of its consequences.

Encyclopedia of Biomedical Gerontology

Encyclopedia of Biomedical Gerontology
Author: Anonim
Publsiher: Academic Press
Total Pages: 1640
Release: 2019-11-20
ISBN 10: 0128160764
ISBN 13: 9780128160763
Language: EN, FR, DE, ES & NL

Encyclopedia of Biomedical Gerontology Book Review:

Encyclopedia of Biomedical Gerontology presents a wide range of topics, ranging from what happens in the body during aging, the reasons and mechanisms relating to those age-related changes, and their clinical, psychological and social modulators and determinants. The book covers the biological and medical aspects of gerontology within the general framework of the biological basis of assessing age, biological mechanisms of aging, age-related changes in biological systems, human age-related diseases, the biomedical practicality and impracticality of interventions, and finally, the ethics of intervention. Provides a ‘one-stop’ resource to information written by world-leading scholars in the field of biomedical gerontology Fills a critical gap of information in a field that has seen significant progress in the last 10 years

Orthogeriatrics

Orthogeriatrics
Author: Paolo Falaschi,David R. Marsh
Publsiher: Springer
Total Pages: 211
Release: 2016-09-19
ISBN 10: 3319432494
ISBN 13: 9783319432496
Language: EN, FR, DE, ES & NL

Orthogeriatrics Book Review:

This book focuses on orthogeriatrics, a topic that has received little attention in the literature to date. As active members of the Fragility Fracture Network (FFN), the editors and most of the authors of this book have gathered all essential expertise on hip fracture management in a single volume. The 14 chapters provide a complete overview of how to approach fractures in elderly patients, starting with the epidemiology of hip fractures and subsequently addressing osteoporosis, surgery, anesthesia, medical management of frailty, and peri-operative complications. Attention is also given to rehabilitation and nursing, as well as to the psychological evaluation of the patient and the caregivers, thus emphasizing the importance of a multidisciplinary approach. Thanks to its clinical and practice-oriented nature, the book will especially be of interest to residents and young geriatricians, as well as orthopaedic surgeons, anesthesiologists and nurses dealing with elderly fracture patients in all parts of the world.

The Molecular Genetics of Aging

The Molecular Genetics of Aging
Author: Siegfried Hekimi
Publsiher: Springer Science & Business Media
Total Pages: 240
Release: 2012-12-06
ISBN 10: 354048003X
ISBN 13: 9783540480037
Language: EN, FR, DE, ES & NL

The Molecular Genetics of Aging Book Review:

The molecular genetics of aging or life-span determination is an expanding field. One reason is because many people would consider it desirable if hu man life span could be extended. Indeed, it is difficult not to be fascinated by tales of the life and death of people who have succeeded in living a very long life. Because of this, we have placed at the head of this book the chapter by Perls et al. on Centenerians and the Genetics of Longevity. Perls and his coauthors convincingly argue that, while the average life expectancy might be mostly determined by environmental factors because the average person has an average genotype, extremely long life spans are genetically determined. Of course, studying humans to uncover the genetics of aging is not ideal, not so much because one cannot easily perform experiments as because they live such a long time. This is why most of this book describes the current state of research with model organisms such as yeast, worms, flies, and mice. J aswinski focuses on yeast and how metabolic activity and stress resistance affect the longevity of Saccharomyces cerevisiae. In the process, he discusses the concept of aging as applied to a unicellular organism such as yeast and the importance of metabolism and stress resistance for aging in all organisms.

Health Illness and Optimal Aging

Health  Illness  and Optimal Aging
Author: Carolyn M. Aldwin,Dr Diane F Gilmer,Diane F. Gilmer
Publsiher: SAGE
Total Pages: 418
Release: 2004
ISBN 10: 9780761922599
ISBN 13: 0761922598
Language: EN, FR, DE, ES & NL

Health Illness and Optimal Aging Book Review:

In Health, Illness, and Optimal Aging: Biological and Psychosocial Perspectives, Carolyn M. Aldwin and Diane F. Gilmer undertake the challenging task of assembling an objective and holistic picture of human aging. The authors provide comprehensive, multidisciplinary coverage of the physical aspects of aging, including age-related changes and disease-related processes, the demography of the aging population, theories of aging, and the promotion of optimal aging. In addition, the book covers the psychosocial aspects of aging, including mental health, stress and coping, spirituality, and care giving in later years. Health, Illness and Optimal Aging is recommended for researchers seeking an overview of health psychology and aging, as well as undergraduate and graduate students taking classes in the social, behavioral, and health sciences. This text is also valuable for practitioners working with the elderly in fields such as nursing, social work, occupational and physical therapy, day-care and nursing home administration, psychology, and rehabilitation.

Hot Topics in Endocrine and Endocrine Related Diseases

Hot Topics in Endocrine and Endocrine Related Diseases
Author: Monica Fedele
Publsiher: BoD – Books on Demand
Total Pages: 276
Release: 2013-05-08
ISBN 10: 9535110802
ISBN 13: 9789535110804
Language: EN, FR, DE, ES & NL

Hot Topics in Endocrine and Endocrine Related Diseases Book Review:

This book covers a selected number of hot topics in endocrine and hormone-related pathologies, discussed by eminent scientists and clinicians coming from different countries of the world. It deals with advanced recent trends in the field, including neuroendocrine and pituitary tumors, thyroid dysfunctions, diabetes and a series of endocrine-related diseases, such as those related to the anabolic effects of testosterone, obesity, cancer, the liver complications of diabetes and the pediatric nonalcoholic fatty liver disease. The readers should be able to have a basic, as well as critic and advanced, overview of these selected hot pathologies of the endocrine system.

Multidisciplinary Approach to Osteoporosis

Multidisciplinary Approach to Osteoporosis
Author: Andrea Lenzi,Silvia Migliaccio
Publsiher: Springer
Total Pages: 330
Release: 2018-09-04
ISBN 10: 3319751107
ISBN 13: 9783319751108
Language: EN, FR, DE, ES & NL

Multidisciplinary Approach to Osteoporosis Book Review:

This book describes in detail the multidisciplinary management of osteoporosis, providing readers with a thorough understanding of the rationale for a multidisciplinary approach and with the tools required to implement it effectively. The emphasis is on a translational approach, starting from basic concepts and fundamental mechanisms of the pathology and clinical morbidity. Experts in the field discuss the full range of relevant topics, including the significance of physical activity, nutritional strategies, and pharmacological treatment. Put another way, the book covers all aspects from the bench to the bedside. Physicians, scientists, and postgraduate students will all find it to be invaluable in understanding the causes and optimal management of osteoporosis, the incidence of which is increasing rapidly as populations age.

An Essay on the Shaking Palsy

An Essay on the Shaking Palsy
Author: James Parkinson
Publsiher: Unknown
Total Pages: 66
Release: 1817
ISBN 10:
ISBN 13: NWU:35558004985954
Language: EN, FR, DE, ES & NL

An Essay on the Shaking Palsy Book Review:

Falls and Cognition in Older Persons

Falls and Cognition in Older Persons
Author: Manuel Montero-Odasso,Richard Camicioli
Publsiher: Springer Nature
Total Pages: 436
Release: 2019-10-04
ISBN 10: 3030242331
ISBN 13: 9783030242336
Language: EN, FR, DE, ES & NL

Falls and Cognition in Older Persons Book Review:

Despite of the enormous efforts of researchers and clinicians to understand the pathophysiology of falls in older adults and establish preventive treatments, there is still a significant gap in our understanding and treating of this challenging syndrome, particularly when we focus in cognitively impaired older adults. Falls in older adults are a very common yet complex medical event, being the fifth leading cause of death and a main cause of insidious disability and nursing home placement in our world aging population. Importantly, falls in the cognitively impaired double the prevalence of the cognitively normal, affecting up of 60% of older adults with low cognition and increasing the risk of injuries. The past decade has witnessed an explosion of new knowledge in the role of cognitive processes into the falls mechanisms. This was also accompanied with clinical trials assessing the effect of improving cognition via pharmacological and non-pharmacologic approaches to prevent falls and related injuries. Unfortunately, this revolution in emerging interventions left a gap between clinician-scientists and researchers at academic centers where the new data had been generated and the practitioners who care for cognitively impaired patients with falls. Most advances are published in specialty journals of geriatric medicine, neurology, and rehabilitation. The aim of this book is to reduce this gap and to provide practical tools for fall prevention in cognitively impaired populations. The proposed book is designed to present a comprehensive and state-of the-art update that covers the pathophysiology, epidemiology, and clinical presentation of falls in cognitively impaired older adults. We additionally aim to reduce the knowledge gap in the association between cognitive processes and falls for practitioners from a translational perspective: from research evidence to clinical approach. We will address gaps and areas of uncertainty but also we will provide practical evidence-based guidelines for the assessment, approach, and treatment of falls in the cognitively impaired populations. This book is a unique contribution to the field. Existing textbooks on fall prevention focus in global approaches and only tangentially address the cognitive component of falls and not purposely address special populations and/or settings as residential care and nursing homes. Due to the expected increase of proportion of older adults with cognitive and mobility impairments, this book is also valuable for the whole spectrum of the health care of the elderly. By including a transdisciplinary perspective from geriatric medicine, rehabilitation and physiotherapy medicine, cognitive neurology, and public health, this book will provide a practical and useful resource with wide applicability in falls assessment and prevention.

Nutritional Influences on Bone Health

Nutritional Influences on Bone Health
Author: Connie M. Weaver,Robin M. Daly,Heike A. Bischoff-Ferrari
Publsiher: Springer
Total Pages: 335
Release: 2016-08-01
ISBN 10: 3319324179
ISBN 13: 9783319324173
Language: EN, FR, DE, ES & NL

Nutritional Influences on Bone Health Book Review:

The 9th International Symposium is the only regular meeting in the bone field to be exclusively devoted to nutrition, bone and muscle, and it allows the authors of this book to review the new scientific data, discuss new concepts, and update the knowledge on several nutrients. The Symposium provides a unique opportunity to connect health professionals, researchers and industry across many disciplines, including nutrition and dietetics, exercise science, gerontology, nursing, general practice, academia and the food and fitness industry. Most causes for osteoporosis, like genetics, age, menopause, and associated diseases with their treatments, are not modifiable. The investigation of the influence of nutrition on bone health is important as a key modifiable factor of the development of bone and the prevention of osteoporosis. It is the privilege of this symposium to gather every three years with scientists from all over the world working in this field.

Providing Healthy and Safe Foods As We Age

Providing Healthy and Safe Foods As We Age
Author: Institute of Medicine,Food and Nutrition Board,Food Forum
Publsiher: National Academies Press
Total Pages: 192
Release: 2010-11-29
ISBN 10: 0309158834
ISBN 13: 9780309158831
Language: EN, FR, DE, ES & NL

Providing Healthy and Safe Foods As We Age Book Review:

Does a longer life mean a healthier life? The number of adults over 65 in the United States is growing, but many may not be aware that they are at greater risk from foodborne diseases and their nutritional needs change as they age. The IOM's Food Forum held a workshop October 29-30, 2009, to discuss food safety and nutrition concerns for older adults.

Stress Responses

Stress Responses
Author: Christine M. Oslowski
Publsiher: Humana Press
Total Pages: 246
Release: 2015-03-25
ISBN 10: 9781493925216
ISBN 13: 1493925210
Language: EN, FR, DE, ES & NL

Stress Responses Book Review:

This volume focuses on detecting different cellular stresses, measuring pathological consequences within the cell, and investigating the role of cellular stresses in select diseases. In addition, this book reviews the crosstalk between different stress pathways, stress responses during ageing, and targeting stress for regenerative medicine. Written in the highly successful Methods of Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and key tips on troubleshooting and avoiding known pitfalls. Authoritative and instructive, Stress Responses: Methods and Protocols seeks to aid scientists to further study multiple stress pathways and outcomes triggered by such stresses. In depth knowledge of cellular stress will eventually lead to the development of novel therapeutics to prevent or treat related diseases.

The Osteoporosis Primer

The Osteoporosis Primer
Author: Janet E. Henderson,David Goltzman
Publsiher: Cambridge University Press
Total Pages: 372
Release: 2000-08-24
ISBN 10: 9780521644464
ISBN 13: 0521644461
Language: EN, FR, DE, ES & NL

The Osteoporosis Primer Book Review:

The Osteoporosis Primer provides an excellent introduction that relates the clinical presentation of osteoporosis to its molecular biochemical basis, and reviews therapeutic options.

Rehabilitation Medicine for Elderly Patients

Rehabilitation Medicine for Elderly Patients
Author: Stefano Masiero,Ugo Carraro
Publsiher: Springer
Total Pages: 545
Release: 2017-09-04
ISBN 10: 331957406X
ISBN 13: 9783319574066
Language: EN, FR, DE, ES & NL

Rehabilitation Medicine for Elderly Patients Book Review:

This book clearly explains when and how different rehabilitation techniques should be applied in the aging patient, thereby enabling readers to identify and apply those rehabilitation strategies that will maximize quality of life and functional independence in individual cases. It is specifically designed for ease of consultation and rapid retrieval of the information most relevant to clinical practice. Prominence is given to the benefits of a multidisciplinary approach to rehabilitation, with discussion of a very wide range of aspects of rehabilitation in different disease settings. The breadth of coverage is illustrated by the attention paid to less commonly addressed topics such as visual and hearing rehabilitation, the role of robotics and 3D imaging techniques, variations in approach among health care systems, and rehabilitation in end-of-life care. The authors are international academic experts in their fields, guaranteeing a high scientific standard throughout. This manual will be an invaluable tool and source of knowledge for geriatricians and physiatrists but will also appeal to a wider range of clinicians, practitioners, and students.