Ocular Transporters and Receptors

Ocular Transporters and Receptors
Author: Ashim K Mitra
Publsiher: Elsevier
Total Pages: 276
Release: 2013-10-31
ISBN 10: 190881831X
ISBN 13: 9781908818317
Language: EN, FR, DE, ES & NL

Ocular Transporters and Receptors Book Review:

Ocular transporters and receptors contains detailed descriptions of major transporters and receptors expressed in the eye, with special emphasis on their role in drug delivery. The complex anatomy and the existence of multiple barriers in the eye pose a considerable challenge to successful drug delivery to the eye. Hence ocular transporters and receptors are important targets for drug delivery. A significant advancement has been made in the field of ocular transport research and their role in drug delivery. In this book the cutting edge research being carried out in this field is compiled and summarized. The book focuses on key areas, including the anatomy and physiology of the eye, biology of ocular transporters and receptors, techniques in characterization of transporters and receptors, transporters and receptors in the anterior and posterior segment in the eye, the role of ocular transporters and receptors in drug delivery, and transporter-metabolism interplay in the eye. Highly focused on ocular transporters Most up-to-date research compilation Detailed description of role of transporters and receptors in ocular drug discovery and delivery

Ocular Transporters in Ophthalmic Diseases and Drug Delivery

Ocular Transporters in Ophthalmic Diseases and Drug Delivery
Author: Joyce Tombran-Tink,Colin J. Barnstable
Publsiher: Springer Science & Business Media
Total Pages: 467
Release: 2008-04-09
ISBN 10: 9781597453752
ISBN 13: 1597453757
Language: EN, FR, DE, ES & NL

Ocular Transporters in Ophthalmic Diseases and Drug Delivery Book Review:

In this exceptionally important new work, a panel of distinguished authors discusses all the latest developments in the study of ocular transporters. Focusing on the molecular characteristics, localization, and substrate specificities in various compartments of the eye, this volume discusses how transporters regulate the clarity of the cornea and lens, the movements of fluids across the ciliary epithelium and nutrients across the retinal pigment epithelium.

Cell Biology of the Eye

Cell Biology of the Eye
Author: David Mcdevitt
Publsiher: Elsevier
Total Pages: 584
Release: 2012-12-02
ISBN 10: 0323145213
ISBN 13: 9780323145213
Language: EN, FR, DE, ES & NL

Cell Biology of the Eye Book Review:

Cell Biology of the Eye discusses the eye tissues and its role in the investigations on active transport, growth factors, receptors, and differentiation. The book is comprised of articles which discuss corneal proteoglycans; transport of ions and metabolites across the corneal endothelium; the ontogeny and localization of the crystallins in eye lens development and regeneration; the biological-physical basis of lens transparency; the chromatic organization of the retina; and the dopamine neurons in the retina. This treatise will serve as a valuable reference text for graduate and professional students, teachers, researchers, clinicians, and to all in the vision field.

Mechanisms of Water and Solute Transport at the Ocular Surface

Mechanisms of Water and Solute Transport at the Ocular Surface
Author: Marc Harris Levin
Publsiher: Unknown
Total Pages: 275
Release: 2006
ISBN 10:
ISBN 13: UCAL:X85575
Language: EN, FR, DE, ES & NL

Mechanisms of Water and Solute Transport at the Ocular Surface Book Review:

Actions of and interactions among AQPs, CFTR, and ENaC are also of central importance to airway surface liquid (ASL) function and dysfunction, and have been considered with regard to both the etiology and possible treatment of cystic fibrosis (CF) lung disease. Recent data indicated clinical benefit of nebulized hypertonic saline in CF. The proposed mechanism of increased ASL volume relies on purported inhibition of lung AQPs by the ENaC inhibitor amiloride. Sensitive fluorescence methods indicated that amiloride does not inhibit AQP-mediated airway water permeability, indicating the need to identify alternate mechanisms for clinical benefit of hypertonic saline.

Pharmacology of Ocular Therapeutics

Pharmacology of Ocular Therapeutics
Author: Thirumurthy Velpandian
Publsiher: Springer
Total Pages: 535
Release: 2016-02-29
ISBN 10: 3319254987
ISBN 13: 9783319254982
Language: EN, FR, DE, ES & NL

Pharmacology of Ocular Therapeutics Book Review:

This book comprises an integrated review of ocular therapeutics across all relevant fields. It addresses the real-world requirements of ophthalmologists, pharmacists and optometrists, as observed through working alongside these practitioners for two decades. Knowledge surrounding agents used in ophthalmic practice has, historically, been scattered. The book facilitates understanding of ocular drug therapy by compiling all key aspects of the pharmacology, toxicology, pharmaceutical science, ocular biochemistry and cell biology of these agents. Chapters detail drug transfer across barriers, systemic toxicity of topically applied drugs, autonomic drugs used for diagnostics, as well as anti-inflammatory, antiallergic, glaucoma and antimicrobial therapies, and avenues for the development of new ocular drugs. Applications of extemporaneously prepared formulations are described to inform day-to-day clinical practice. The use of mucoadhesive polymers in tear substitutes, ocular drug delivery systems, stem cell therapy, pharmacogenomics and antiangiogenic ocular chemotherapy are also explored. The book also provides insights from drugs of herbal origin, and a historical perspective on drugs for ocular use. Practicing and resident ophthalmologists, optometrists, pharmacists, nursing professionals, scholars in ocular drug research and students will equally benefit from this comprehensive guide.

Drug Delivery

Drug Delivery
Author: Ashim K. Mitra,Chairman and Curator's Professor Pharmaceutical Sciences University of Missouri Kansas City Missouri Ashim K Mitra,Deep Kwatra,Aswani Dutt Vadlapudi
Publsiher: Jones & Bartlett Publishers
Total Pages: 400
Release: 2014-08-18
ISBN 10: 1449674267
ISBN 13: 9781449674267
Language: EN, FR, DE, ES & NL

Drug Delivery Book Review:

Drug Delivery is the latest and most up-to-date text on drug delivery and offers an excellent working foundation for students and clinicians in health professions and graduate students including nursing, pharmacy, medicine, dentistry, as well as researchers and scientists. Presenting this complex content in an organized and concise format, Drug Delivery allows students to gain a strong understanding of the key concepts of drug delivery.This text focuses on the basic concepts of drug delivery while thoroughly examining various topics such as: CNS delivery Gene delivery Ocular delivery World-wide research on drug delivery Recent advances in drug deliveryA significant advancement has been made in the field of drug delivery. This text provides a detailed overview of drug delivery systems, routes of drug administration and development of various formulations. The cutting edge research being carried out in this field will be compiled and a focus on worldwide research on drug delivery and targeting at the molecular, cellular, and organ levels will also be summarized.Each new print copy includes access to the Navigate Companion Website including: Chapter Quizzes, Interactive Glossary, Crossword Puzzles , Interactive Flashcards, and Matching Exercises

Current Eye Research

Current Eye Research
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1985
ISBN 10:
ISBN 13: NWU:35558000849360
Language: EN, FR, DE, ES & NL

Current Eye Research Book Review:

Encyclopedia of the Eye

Encyclopedia of the Eye
Author: Joseph Besharse,Reza Dana,Barbara Ann Battelle,David Beebe,Peter Bex,Paul Bishop,Dean Bok,Patricia D’Amore,Henry Edelhauser,Linda Mcloon,Jerry Niederkorn,Thomas A. Reh,Ernst R. Tamm
Publsiher: Academic Press
Total Pages: 2344
Release: 2010-05-27
ISBN 10: 012374203X
ISBN 13: 9780123742032
Language: EN, FR, DE, ES & NL

Encyclopedia of the Eye Book Review:

As the first comprehensive reference for the eye, its support structures, diseases, and treatments, Encyclopedia of the Eye is an important resource for all visual scientists, ophthalmologists, and optometrists, as well as researchers in immunology, infectious disease, cell biology, neurobiology and related disciplines. This four-volume reference is unique in its coverage of information on all tissues important for vision, including the retina, cornea and lens. It also covers the physiological and pathophysiologic processes that affect all eye tissues. This Encyclopedia is invaluable for graduate students and postdoctoral fellows who are seeking an introduction to an area of eye research. Each chapter explains the basic concepts and provides references to relevant chapters within the Encyclopedia and more detailed articles across the wider research literature. The Encyclopedia is also particularly useful for visual scientists and practitioners who are researching a new area, seeking deeper understanding of important research articles in fields adjacent to their own, or reviewing a grant outside their immediate area of expertise. Written by experts at a level that permits students to grasp key elements of a specific subject Provides an entryway into the major features of current eye research No other source puts this much information, so well-indexed and with so many helpful full color figures and graphics, in the hands of the ophthalmic scientist

Lacrimal Gland Tear Film and Dry Eye Syndromes 3

Lacrimal Gland  Tear Film  and Dry Eye Syndromes 3
Author: David A. Sullivan,Michael E. Stern,Kazuo Tsubota,Darlene A. Dartt,Rose M. Sullivan,B. Britt Bromberg
Publsiher: Springer
Total Pages: 1399
Release: 2003-01-31
ISBN 10: 9780306472824
ISBN 13: 0306472821
Language: EN, FR, DE, ES & NL

Lacrimal Gland Tear Film and Dry Eye Syndromes 3 Book Review:

During the past several decades, a significant international research effort has been directed towards understanding the composition and regulation of the preocular tear film. This effort has been motivated by the recognition that the tear film plays a critical role in maintaining corneal and conjunctival integrity, protecting against microbial challenge and preserving visual acuity. In addition, research has been stimulated by the knowledge that alteration or deficiency of the tear film, which occurs in numerous individuals throughout the world, may lead to desiccation of the ocular surface, ulceration and perforation of the cornea, an increased incidence of infectious disease, and potentionally pronounced visual disability and blindness.

Jules Stein Eye Institute

Jules Stein Eye Institute
Author: Jules Stein Eye Institute
Publsiher: Unknown
Total Pages: 329
Release: 1996
ISBN 10:
ISBN 13: UCLA:L0077332260
Language: EN, FR, DE, ES & NL

Jules Stein Eye Institute Book Review:

Webvision

Webvision
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2017
ISBN 10:
ISBN 13: OCLC:972149258
Language: EN, FR, DE, ES & NL

Webvision Book Review:

Drug Transporters in Drug Disposition Effects and Toxicity

Drug Transporters in Drug Disposition  Effects and Toxicity
Author: Xiaodong Liu,Guoyu Pan
Publsiher: Springer Nature
Total Pages: 580
Release: 2019-09-30
ISBN 10: 9811376476
ISBN 13: 9789811376474
Language: EN, FR, DE, ES & NL

Drug Transporters in Drug Disposition Effects and Toxicity Book Review:

This book provides with a comprehensive overview of the role of drug transporters in drug disposition and efficacy/toxicity, as well as drug-drug interactions and recent advances in the field. Transporters are known determinants of drug disposition and efficacy/toxicity. In general, they are divided into solute carrier (SLC) and ATP binding cassette (ABC) families, and are located along cell membranes, where they mediate drug uptake into cells and export out of cells. Drug transporters are essential in maintaining cell homeostasis, and their gene mutations may cause or contribute to severe human genetic disorders, such as cystic fibrosis, neurological disease, retinal degeneration, anemia, and cholesterol and bile transport defects. Conversely, some diseases may also alter transporter functions and expressions, in turn aggravating disease process. Further, since over-expression of some ABC transporters is a potential contributor to multidrug-resistance (MDR), the book presents a number of strategies to overcome MDR, including ABC transporter inhibitors and applying epigenetic methods to modulate transporter expressions and functions. This book is useful for graduate students and professionals who are looking to refresh or expand their knowledge of this exciting field.

Ophthalmic Drug Delivery Systems

Ophthalmic Drug Delivery Systems
Author: Ashim K. Mitra
Publsiher: CRC Press
Total Pages: 847
Release: 2019-12-02
ISBN 10: 9780367446765
ISBN 13: 0367446766
Language: EN, FR, DE, ES & NL

Ophthalmic Drug Delivery Systems Book Review:

The second edition of this text assembles significant ophthalmic advances and encompasses breakthroughs in gene therapy, ocular microdialysis, vitreous drug disposition modelling, and receptor/transporter targeted drug delivery.

Clinical Ocular Pharmacology

Clinical Ocular Pharmacology
Author: Jimmy D. Bartlett,Siret D. Jaanus
Publsiher: Butterworth-Heinemann
Total Pages: 978
Release: 1984
ISBN 10:
ISBN 13: UOM:39015006017100
Language: EN, FR, DE, ES & NL

Clinical Ocular Pharmacology Book Review:

Written by experts in the field, this comprehensive resource offers valuable information on the practical uses of drugs in primary eye care. Discussions of the pharmacology of ocular drugs such as anti-infective agents, anti-glaucoma drugs, and anti-allergy drugs lead to more in-depth information on ocular drugs used to treat a variety of disorders, including diseases of the eyelids, corneal diseases, ocular infections, and glaucoma. The book also covers ocular toxicology, focusing on drug interactions, ocular effects of systemic drugs, and life-threatening systemic emergencies.

Investigative Ophthalmology Visual Science

Investigative Ophthalmology   Visual Science
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1994-10
ISBN 10:
ISBN 13: NWU:35558003263890
Language: EN, FR, DE, ES & NL

Investigative Ophthalmology Visual Science Book Review:

Ophthalmic Research

Ophthalmic Research
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1970
ISBN 10:
ISBN 13: UCLA:31158008392234
Language: EN, FR, DE, ES & NL

Ophthalmic Research Book Review:

Chitin Chitosan

Chitin Chitosan
Author: Rajendra Dongre
Publsiher: BoD – Books on Demand
Total Pages: 382
Release: 2018-07-18
ISBN 10: 1789234069
ISBN 13: 9781789234060
Language: EN, FR, DE, ES & NL

Chitin Chitosan Book Review:

Chitin is the second most abundant biopolymer after cellulose and is a resourceful copious and cheap biomaterial discovered in 1859 owing to significant industrial and technological utility. Raw chitin-chitosan resembles keratin in its biological functions. Chitin chemistry vastly developed via innate unparalleled biological features and exceptional physicochemical characters. Chitosan endures assorted chemical/physical modifications easily at free proactive functionalities, yet intact bulk properties are achieved through processing, viz., film, membrane, composite, hybrid, nanofibre, nanoparticle, hydrogel and scaffolds. Rapidly lessen bioresources signify chitosan as an option due to renewable eco-friendliness and drive embryonic myriad applications in S

Handbook of Ocular Therapeutics and Pharmacology

Handbook of Ocular Therapeutics and Pharmacology
Author: Philip P. Ellis,Donn L. Smith
Publsiher: Unknown
Total Pages: 251
Release: 1969
ISBN 10:
ISBN 13: UOM:39015072251559
Language: EN, FR, DE, ES & NL

Handbook of Ocular Therapeutics and Pharmacology Book Review:

Pharmacologic Therapy of Ocular Disease

Pharmacologic Therapy of Ocular Disease
Author: Scott M. Whitcup,Dimitri T. Azar
Publsiher: Springer
Total Pages: 389
Release: 2017-06-22
ISBN 10: 3319582909
ISBN 13: 9783319582900
Language: EN, FR, DE, ES & NL

Pharmacologic Therapy of Ocular Disease Book Review:

There have been major advancements in the pharmacologic treatment of eye diseases over the past decade. With newly discovered disease targets and novel approaches to deliver therapeutic compounds to the eye, patients are seeing improved outcomes. Not only are there better treatments for diseases where treatments existed, we now have effective therapy for previously untreatable and blinding eye disorders. This volume will cover the pharmacologic treatment of eye diseases from the front of the eye including eyelids, conjunctiva and cornea all the way back to the retina and optic nerve. The first section of the volume reviews general principles of ocular pharmacology, pharmacokinetics, pharmaceutical sciences, and drug delivery. In addition, the volume provides an up to date guide to the pharmacologic approach to the key eye diseases that threaten sight or ocular function.

Bacterial Physiology

Bacterial Physiology
Author: Walid El-Sharoud
Publsiher: Springer Science & Business Media
Total Pages: 371
Release: 2007-12-07
ISBN 10: 3540749217
ISBN 13: 9783540749219
Language: EN, FR, DE, ES & NL

Bacterial Physiology Book Review:

The application of new molecular methodologies in the study of bacterial behavior and cell architecture has enabled new revolutionary insights and discoveries in these areas. This new text presents recent developments in bacterial physiology that are highly relevant to a wide range of readership including those interested in basic and applied knowledge. Its chapters are written by international scientific authorities at the forefront of the subject. The value of this recent knowledge in bacterial physiology is not only restricted to fundamental biology. It also extends to biotechnology and drug-discovery disciplines.