Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies

Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies
Author: Shi Hu
Publsiher: Academic Press
Total Pages: 300
Release: 2021-03-15
ISBN 10: 9780128215845
ISBN 13: 0128215844
Language: EN, FR, DE, ES & NL

Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies Book Review:

Novel Sensitizing Agents for Therapeutic Anti-EGFR Antibodies presents an in-depth description of sensitizers to overcome resistance to anti-EGFR targeted antibody therapies in cancer, including novel engineered antibody drugs or other sensitizers. It gives an insight into the landscape of anti-EGFR based cancer treatment, the challenges of targeted therapy, and a glimpse into the future of antibody therapy. The book offers pertinent basic science information on strategies used for the rational design and discovery of novel sensitizing agents, and, in addition, translational studies involving pre-clinical and clinical design and execution with these novel agents. It covers basic science strategies that are being used in drug discovery and preclinical evaluation focused on EGFR blockage resistance, as well as clinical trial methodology including clinical pharmacokinetics and imaging to address issues of efficacy evaluation of the new anticancer sensitizers for anti-EGFR drug resistance. This book is an indispensable resource for cancer researchers, medicinal chemists, and other biomedical scientists involved in the development of new therapeutic agents to overcome resistance to anti-EGFR treatments. Presents detailed description of history, chemistry, mechanism of action, structure-function relationships, pharmacology, side effects, dosing, and formulation of new sensitizers to anti-EGFR antibodies Provides molecular structures for all novel anticancer drugs and strategies to overcome resistance of anti-EGFR antibodies Encompasses up-to-date information on the cancer drug discovery process, including new research tools, tumor-targeting strategies, and fundamental concepts in the emerging areas of precision medicine

Novel Therapies in Head and Neck Cancer: Beyond the Horizon

Novel Therapies in Head and Neck Cancer: Beyond the Horizon
Author: Maie A. St. John,No hee Park
Publsiher: Academic Press
Total Pages: 266
Release: 2020-06-29
ISBN 10: 0128209291
ISBN 13: 9780128209295
Language: EN, FR, DE, ES & NL

Novel Therapies in Head and Neck Cancer: Beyond the Horizon Book Review:

Novel Therapies in Head and Neck Cancer: Beyond the Horizon, Volume Twelve, provides a high-level synthesis of the latest treatments and outcomes relating to head and neck cancer. Chemotherapy and immunotherapy for those cancer types are rapidly evolving, and an updated source based on the expertise of internationally renowned researchers is necessary. This book discusses the outcome of recent trials using chemotherapy, novel approaches for HPV+ SCCA, cases in which immunotherapy is more likely to be successful, and precision medicine based on target therapies. Additionally, new approaches for rare diseases in head and neck and novel drug delivery platforms are presented. This book will be a very useful source so that students, scientists and clinicians who can be facile with the data, build on what is known, and continue to offer cutting-edge, validated therapies to all patients. Covers new chemotherapy trials, specifically on HPV and non-HPV related cancer types Discusses the application of immunotherapy to treat rare types of head and neck cancer Presents updated information on targeted therapies, specifically focusing on skin cancer in the region

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy
Author: Anonim
Publsiher: Academic Press
Total Pages: 292
Release: 2018-11-21
ISBN 10: 0128127384
ISBN 13: 9780128127384
Language: EN, FR, DE, ES & NL

Protein Kinase Inhibitors as Sensitizing Agents for Chemotherapy Book Review:

Tyrosine Kinase Inhibitors as Sensitizing Agents for Chemotherapy, the fourth volume in the Cancer Sensitizing Agents for Chemotherapy Series, focuses on strategic combination therapies that involve a variety of tyrosine kinase inhibitors working together to overcome multi-drug resistance in cancer cells. The book discusses several tyrosine kinase inhibitors that have been used as sensitizing agents, such as EGFR, BCR-ABL, ALK and BRAF. In each chapter, readers will find comprehensive knowledge on the inhibitor and its action, including its biochemical, genetic, and molecular mechanisms' emphases. This book is a valuable source for oncologists, cancer researchers and those interested in applying new sensitizing agents to their research in clinical practice and in trials. Summarizes the sensitizing role of some tyrosine kinase inhibitors in existing research Brings recent findings in several cancer types, both experimental and clinically, with a particular emphases on underlying biochemical, genetic, and molecular mechanisms Provides an updated and comprehensive knowledge regarding the field of combinational cancer treatment

Clinical Radiation Oncology E-Book

Clinical Radiation Oncology E-Book
Author: Leonard L. Gunderson,Joel E. Tepper
Publsiher: Elsevier Health Sciences
Total Pages: 1638
Release: 2015-06-16
ISBN 10: 0323370187
ISBN 13: 9780323370189
Language: EN, FR, DE, ES & NL

Clinical Radiation Oncology E-Book Book Review:

Perfect for radiation oncology physicians and residents needing a multidisciplinary, treatment-focused resource, this updated edition continues to provide the latest knowledge in this consistently growing field. Not only will you broaden your understanding of the basic biology of disease processes, you'll also access updated treatment algorithms, information on techniques, and state-of-the-art modalities. The consistent and concise format provides just the right amount of information, making Clinical Radiation Oncology a welcome resource for use by the entire radiation oncology team. Content is templated and divided into three sections -- Scientific Foundations of Radiation Oncology, Techniques and Modalities, and Disease Sites – for quick access to information. Disease Sites chapters summarize the most important issues on the opening page and include a full-color format, liberal use of tables and figures, a closing section with a discussion of controversies and problems, and a treatment algorithm that reflects the treatment approach of the authors. Chapters have been edited for scientific accuracy, organization, format, and adequacy of outcome data (such as disease control, survival, and treatment tolerance). Allows you to examine the therapeutic management of specific disease sites based on single-modality and combined-modality approaches. Features an emphasis on providing workup and treatment algorithms for each major disease process, as well as the coverage of molecular biology and its relevance to individual diseases. Two new chapters provide an increased emphasis on stereotactic radiosurgery (SRS) and stereotactic body irradiation (SBRT). New Associate Editor, Dr. Andrea Ng, offers her unique perspectives to the Lymphoma and Hematologic Malignancies section. Key Points are summarized at the beginning of each disease-site chapter, mirroring the template headings and highlighting essential information and outcomes. Treatment algorithms and techniques, together with discussions of controversies and problems, reflect the treatment approaches employed by the authors. Disease Site Overviews allow each section editor to give a unique perspective on important issues, while online updates to Disease Site chapters ensure your knowledge is current. Disease Site chapters feature updated information on disease management and outcomes. Thirty all-new anatomy drawings increase your visual understanding. Medicine eBook is accessible on a variety of devices.

Gunderson & Tepper’s Clinical Radiation Oncology, E-Book

Gunderson & Tepper’s Clinical Radiation Oncology, E-Book
Author: Joel E. Tepper
Publsiher: Elsevier Health Sciences
Total Pages: 1648
Release: 2019-12-06
ISBN 10: 0323672477
ISBN 13: 9780323672474
Language: EN, FR, DE, ES & NL

Gunderson & Tepper’s Clinical Radiation Oncology, E-Book Book Review:

A comprehensive, multidisciplinary resource for the entire radiation oncology team, Gunderson & Tepper’s Clinical Radiation Oncology, 5th Edition, thoroughly covers all aspects of this complex and dynamic field. Concise, templated chapters cover the basic biology of oncologic disease processes as well as updated treatment algorithms, the latest clinical guidelines, and state-of-the-art techniques and modalities. More than 1,000 images—detailed anatomy drawings, radiographic images, and more—provide outstanding visual support for every area of the text. Divides content into three distinct sections for quick access to information: Scientific Foundations, Techniques and Modalities, and Disease Sites. Disease Site chapters include overviews summarizing the most important issues and concluding discussions on controversies and problems. Features new and expanded content on molecular and cellular biology and its relevance in individualized treatment approaches, stereotactic radiation therapy, radiosurgery, proton therapy, biologic therapy, precision radiation therapy, targeted radiation, dosing guidelines for better quality of life and improved patient outcomes, and more. Includes new chapters on Radiation Physics: Particle Therapy, Interventional Radiology, Radiation Therapy in the Elderly, Palliative Care, Quality and Safety, and Immunotherapy with Radiotherapy. Provides guidance on single-modality and combined-modality approaches, as well as outcome data including disease control, survival, and treatment tolerance. Includes access to videos on Intraoperative Irradiation, Prostate Brachytherapy, Penile Brachytherapy, and Ocular Melanoma.

Surgical Decision Making E-Book

Surgical Decision Making E-Book
Author: Robert C. McIntyre,Richard D. Schulick
Publsiher: Elsevier Health Sciences
Total Pages: 512
Release: 2019-01-08
ISBN 10: 0323567916
ISBN 13: 9780323567916
Language: EN, FR, DE, ES & NL

Surgical Decision Making E-Book Book Review:

Using a proven, practical, algorithmic approach, Surgical Decision Making summarizes evidence-based guidelines and practice protocols in an easy-to-follow format. Designed to sharpen the decision-making skills of both trainees and practicing surgeons, the 6th Edition directs your focus to the critical decision points in a wide range of clinical scenarios, helping you determine optimal evaluation and management to secure the best possible patient outcomes. Algorithms are accompanied by annotations that explain all critical factors affecting decisions in a concise, readable manner. Reflects the scope of practice of today’s general surgeon, with fresh, expert perspectives from new editor Dr. Richard Schulick and numerous new contributors. Contains 58 new chapters and thoroughly revised content throughout. Includes new coverage of Preoperative Evaluation of the Geriatric Patient, Pancreatic Cystic Neoplasm, Familial Breast Cancer, Resuscitative Endovascular Balloon Occlusion of the Aorta, Blunt Cerebrovascular Injury, and much more. Uses an easy-to-follow, consistent format, with an algorithm on one page and short descriptions explaining the various steps in the decision-making process on the opposite page. Includes explanatory notes that summarize presenting signs and symptoms, laboratory investigation, diagnostic modalities, surgical therapies, and adjuvant therapies for each condition. Encompasses both general surgery and surgical subspecialties―helping you directly manage a broad range of problems. Emphasizes information that frequently appears on board exams.

Cancer Drug Resistance

Cancer Drug Resistance
Author: Beverly A. Teicher
Publsiher: Springer Science & Business Media
Total Pages: 617
Release: 2007-11-09
ISBN 10: 1597450359
ISBN 13: 9781597450355
Language: EN, FR, DE, ES & NL

Cancer Drug Resistance Book Review:

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

Oncology of Infancy and Childhood E-Book

Oncology of Infancy and Childhood E-Book
Author: Stuart H. Orkin,David E. Fisher,A. Thomas Look,Samuel Lux,David Ginsburg,David G. Nathan
Publsiher: Elsevier Health Sciences
Total Pages: 1392
Release: 2009-06-09
ISBN 10: 1437721389
ISBN 13: 9781437721386
Language: EN, FR, DE, ES & NL

Oncology of Infancy and Childhood E-Book Book Review:

To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes. With this volume devoted strictly to pediatric oncology, and another to pediatric hematology, you will be on the cutting edge of these two fields. This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. Written by the leading names in pediatric oncology, this resource is an essential tool for all who care for pediatric cancer patients. Offers comprehensive coverage of all pediatric cancers, including less common tumors, making this the most complete guide to pediatric cancer. Covers emerging research developments in cancer biology and therapeutics, both globally and in specific pediatric tumors. Includes a section on supportive care in pediatric oncology, written by authors who represent the critical subdisciplines involved in this important aspect of pediatric oncology. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines. Presents a full-color design that includes clear illustrative examples of the relevant pathology and clinical issues, for quick access to the answers you need. Incorporates the codified WHO classification for all lymphomas and leukemias.

Improving the Therapeutic Ratio in Head and Neck Cancer

Improving the Therapeutic Ratio in Head and Neck Cancer
Author: Anonim
Publsiher: Academic Press
Total Pages: 376
Release: 2019-10-04
ISBN 10: 0128178698
ISBN 13: 9780128178690
Language: EN, FR, DE, ES & NL

Improving the Therapeutic Ratio in Head and Neck Cancer Book Review:

Improving the Therapeutic Ratio in Head and Neck Cancer provides a complete review of current approaches to modulating therapeutic sensitivity in head and neck cancer. It presents a broad background of current approaches and by highlighting the potential for clinical translational, introduces a roadmap for how to move promising preclinical findings into the clinic. The book discusses topics such as immunotherapy and molecularly targeted therapies in head and neck cancer, PI3k/mTOR pathway, autophagy inhibition to sensitize HNC to radiation and chemotherapy, TAM and Eph/Ephrin family proteins and metabolic reprogramming to modulate therapeutic sensitivity. Additionally, it details approaches to improve the response to immunotherapy, and Chk1/2 inhibition in radiation and cetuximab resistance. This book is a valuable source to head and neck cancer researchers and advanced students, and to those studying specific approaches in other model systems and disease sites. Provides key scientific background for clinicians when developing novel clinical trials and important examples for basic scientists of the types of work required to move a concept from the lab to the clinic Presents consistent pathway diagrams in each chapter, thus making it easier to understand complicated pathways Includes chapter summaries of the critical next steps needed to move studies from their current state into practice changing clinical data

CURRENT Medical Diagnosis and Treatment 2015 (eBook)

CURRENT Medical Diagnosis and Treatment 2015 (eBook)
Author: Maxine Papadakis,Stephen J. McPhee,Michael W. Rabow
Publsiher: McGraw Hill Professional
Total Pages: 1920
Release: 2014-09-05
ISBN 10: 007182491X
ISBN 13: 9780071824910
Language: EN, FR, DE, ES & NL

CURRENT Medical Diagnosis and Treatment 2015 (eBook) Book Review:

To deliver the best care to your patients, turn to the #1 annually updated guide in internal medicine and clinical practice. The 2015 Edition is packed with important NEW information! For more than 70 years, professors, students, and clinicians have trusted LANGE for high-quality, current, concise medical information in a convenient, affordable, portable format. Whether for coursework, clerkships, USMLE prep, specialty board review, or patient care, there's a LANGE book that guarantees success. NEW TO THIS EDITION: Latest 2014 American Heart Association/American College of Cardiology guidelines for anticoagulation in atrial fibrillation, and indications for interventions in valvular heart disease Update on the epidemic of opioid-based prescription drug abuse, misuse and overdose, and new section on opioids for chronic, noncancer pain Revised treatment options for Helicobacter pylori and chronic hepatitis C Latest hypertension information from 2013 UK National Institute of Health and Clinical Excellence and US Joint National Committee (JNC8) Reports Discussion of which patients benefit from statins, and indications for high vs. moderate intensity statins, based on 2014 AHA/ACC guidelines Scoring tools for assessing the severity of acute pancreatitis Revised psychiatric diagnoses in accordance with the Diagnostic Statistical Manual’s 5th edition No other text links practice and research like CURRENT Medical Diagnosis & Treatment! Written by clinicians renowned in their fields, this trusted annual text offers the most current insight into symptoms, signs, epidemiology, diagnosis, prevention, and treatment for more than 1,000 diseases and disorders. You'll find concise, evidence-based answers to questions about both hospital and ambulatory problems. The streamlined format of each section in this clinical companion is the fastest, easiest way to keep abreast of the latest diagnostic advances, prevention strategies, and cost-effective treatments. Here's why CMDT is essential to your clinical practice: Strong emphasis on the practical aspects of clinical diagnosis and patient management throughout the broad fields of internal medicine Full review of other relevant primary care topics, including obstetrics/gynecology, dermatology, neurology, urology, ophthalmology, orthopedics, geriatrics, women’s health, and palliative care Hundreds of medication treatment tables, with indexed trade names and updated prices Many helpful diagnostic and treatment algorithms Only text with an annual review of advances in HIV treatment Recent references with PMID numbers for easy online access Many full-color photographs and illustrations

Cancer: New Insights for the Healthcare Professional: 2011 Edition

Cancer: New Insights for the Healthcare Professional: 2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 3937
Release: 2012-01-09
ISBN 10: 1464900027
ISBN 13: 9781464900020
Language: EN, FR, DE, ES & NL

Cancer: New Insights for the Healthcare Professional: 2011 Edition Book Review:

Cancer: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Cancer. The editors have built Cancer: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Cancer in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Cancer: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Janeway's Immunobiology

Janeway's Immunobiology
Author: Kenneth Murphy,Paul Travers,Mark Walport,Peter Walter
Publsiher: Garland Science
Total Pages: 329
Release: 2010-06-22
ISBN 10: 9780815344575
ISBN 13: 0815344570
Language: EN, FR, DE, ES & NL

Janeway's Immunobiology Book Review:

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

CURRENT Medical Diagnosis and Treatment 2014

CURRENT Medical Diagnosis and Treatment 2014
Author: Maxine A. Papadakis,Stephen J. McPhee,Michael W. Rabow
Publsiher: McGraw Hill Professional
Total Pages: 1840
Release: 2013-09-02
ISBN 10: 0071806342
ISBN 13: 9780071806343
Language: EN, FR, DE, ES & NL

CURRENT Medical Diagnosis and Treatment 2014 Book Review:

Turn the latest research into improved patient outcomes with the #1 annual guide to internal medicine and clinical practice Written by clinicians renowned in their respective fields, CMDT offers the most current insight into symptoms, signs, epidemiology, diagnosis, and treatment for more than 1,000 diseases and disorders. You'll find concise, evidence-based answers to questions about hospital and ambulatory problems. This streamlined clinical companion is the fastest and easiest way to keep abreast of the latest diagnostic advances, prevention strategies, and cost-effective treatments. Features and content critical to clinical practice: Strong emphasis on the practical aspects of clinical diagnosis and patient management throughout the broad fields of internal medicine Full review of internal medicine and primary care topics, including gynecology and obstetrics, dermatology, neurology, ophthalmology, geriatrics, and palliative care The only text with an annual review of advances in HIV treatment Specific disease prevention information Hundreds of medication treatment tables, with indexed trade names and updated prices – plus helpful diagnostic and treatment algorithms Recent references with PMID numbers Many full-color photographs and illustrations NEW TO THIS EDITION: Update on the evaluation of chest pain New algorithms for the treatment of heart failure and NSTEMI New sections on pulmonary hypertension; treatment of pleural mesothelioma; diagnosis and treatment of subacute, postpartum, and silent thyroiditis and amiodarone- and iodine-induced thyrotoxicosis; and treatment of cryoglobulinemic vasculitis New tables on preferred initial antiretroviral regimen and fixed dose antiretroviral combinations for HIV infection, and on medications for management of diabetes Updated tables on cancer chemotherapeutic and supportive care agents Includes 5 online-only chapters at no additional cost Visit: www.AccessMedicine.com/CMDT

Basic and Clinical Pharmacology 12/E

Basic and Clinical Pharmacology 12/E
Author: Bertram G. Katzung,Susan Masters,Anthony Trevor
Publsiher: McGraw Hill Professional
Total Pages: 1229
Release: 2012-01-03
ISBN 10: 0071764011
ISBN 13: 9780071764018
Language: EN, FR, DE, ES & NL

Basic and Clinical Pharmacology 12/E Book Review:

Looks at the essential conepts in the science of pharmacology and its application to clinical practice.

Drug Resistance in Leukemia &

Drug Resistance in Leukemia &
Author: Gert-Jan L. Kaspers
Publsiher: CRC Press
Total Pages: 436
Release: 1993-01-01
ISBN 10: 9783718653874
ISBN 13: 3718653877
Language: EN, FR, DE, ES & NL

Drug Resistance in Leukemia & Book Review:

The last ten years have seen the publication of a vast amount of data regarding cellular resistance to drugs in cancer cells. Recent studies have demonstrated that drug resistance assays appear to be predictive of clinical response and suggest that clinicians should now be considering the potential applications of these assays in the treatment of patients with hematological neoplasms. This collection of papers from the International Symposium on the Clinical Value of Drug Resistance Assays in Leukemia and Lymphoma, Amsterdam, 1992, provides a state-of-the-art discussion on drug resistance assays and their role in the design and individualization of treatment protocols.

Noble and Precious Metals

Noble and Precious Metals
Author: Mohindar Seehra,Alan Bristow
Publsiher: BoD – Books on Demand
Total Pages: 430
Release: 2018-07-04
ISBN 10: 1789232929
ISBN 13: 9781789232929
Language: EN, FR, DE, ES & NL

Noble and Precious Metals Book Review:

The use of copper, silver, gold and platinum in jewelry as a measure of wealth is well known. This book contains 19 chapters written by international authors on other uses and applications of noble and precious metals (copper, silver, gold, platinum, palladium, iridium, osmium, rhodium, ruthenium, and rhenium). The topics covered include surface-enhanced Raman scattering, quantum dots, synthesis and properties of nanostructures, and its applications in the diverse fields such as high-tech engineering, nanotechnology, catalysis, and biomedical applications. The basis for these applications is their high-free electron concentrations combined with high-temperature stability and corrosion resistance and methods developed for synthesizing nanostructures. Recent developments in all these areas with up-to-date references are emphasized.

New Trends in Cancer for the 21st Century

New Trends in Cancer for the 21st Century
Author: International Symposium on Cancer "New Trends in Cancer for the 21st Century"
Publsiher: Springer Science & Business Media
Total Pages: 293
Release: 2003
ISBN 10: 9780306477621
ISBN 13: 0306477629
Language: EN, FR, DE, ES & NL

New Trends in Cancer for the 21st Century Book Review:

It is difficult to imagine anyone who has not heard of cancer. This disease can affect families, friends or any one of us at any time in our lives. Every year nearly 3 million Europeans are diagnosed with cancer, leading to around 800,000 deaths per year. These deaths occur not only in aging populations, but also in children and adults who are in the most active period of their lives. This represents a tremendous problem that cannot be ignored by politicians or citizens. Fortunately, there is a constantly growing awareness that although cancer is a problem to be dealt with by clinicians, it should also be the concern of everyone. This volume contains the lectures held at the International Symposium on Cancer "New Trends in Cancer for the 21st Century".

Macromolecular Anticancer Therapeutics

Macromolecular Anticancer Therapeutics
Author: L. Harivardhan Reddy,Patrick Couvreur
Publsiher: Springer Science & Business Media
Total Pages: 500
Release: 2010-03-20
ISBN 10: 9781441905079
ISBN 13: 1441905073
Language: EN, FR, DE, ES & NL

Macromolecular Anticancer Therapeutics Book Review:

In spite of the development of various anticancer drugs, the therapy of cancer has remained challenging for decades. The current therapy of cancer is overwhelmed because of the inability to deliver therapeutics to all regions of a tumor in effective therapeutic concentrations, intrinsic or acquired resistance to the treatment with currently available agents via genetic and epigenetic mechanisms, and toxicity. As a result, cancer therapy using conventional therapeutics and different types of treatment regimens using this therapeutics has not led to a convincing survival benefit of the patients. In this context, Macromolecular therapeutics offer several advantages over conventional low molecular therapeutics by various ways such as, enable the use of larger doses of these agents by limiting the toxicity, by enhanced permeability and retention into tumors, by tumor targeting using tumor-specific antibodies, by specific inhibition of oncogenes using anticancer oligonucleotides etc. Cancer treatment using this macromolecular therapeutics has considerably improved the survival benefit for patients. As a result, various macromolecular therapeutics are already commercialized or are under clinical development. Although we are far from a real magic bullet today, looking at the pace of research and current success in this field of macromolecular therapeutics, it appears that we are approaching a magic bullet for the efficient treatment of cancer. Thus, we believe that the subject of this book is very timely, and that the book will fill an unmet need in the market. This book is unique and assembles various types and aspects of macromolecular anticancer therapeutics for cancer therapy in one shell and conveys the importance of this interdisciplinary field to the broad audience. Thus, in a nutshell, this book details the basics of cancer, and various therapeutic strategies such as those based on macromolecular therapeutics hence can become an important reference for practitioners, oncologists, medical pharmacologists, medicinal chemists, biomedical scientists, experimental pharmacologists, pharmaceutical technologists, and particularly it can essentially become a handbook of macromolecular therapeutics for cancer therapy for graduates, post-graduates and Ph.D. students in these fields.

Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics

Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics
Author: Sudip Mukherjee
Publsiher: Morgan & Claypool Publishers
Total Pages: 49
Release: 2019-10-29
ISBN 10: 1643277863
ISBN 13: 9781643277868
Language: EN, FR, DE, ES & NL

Recent Advances in Innovative Magnetic Nanomaterials for Cancer Theranostics Book Review:

In this book, cancer theranostics applications of magnetic iron oxide nanoparticles are overviewed in details. Moreover, their synthesis, characterization, multifunctionality, disease targeting, biodistribution, pharmacokinetics and toxicity have been briefly highlighted. Finally, we have mentioned the current examples of clinical trials of magnetic nanoparticles in cancer theranostics along with their future scopes and challenges.

Indian Journal of Biochemistry & Biophysics

Indian Journal of Biochemistry & Biophysics
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2005
ISBN 10:
ISBN 13: UCLA:L0090608639
Language: EN, FR, DE, ES & NL

Indian Journal of Biochemistry & Biophysics Book Review: