Non Canonical Autophagy

Non Canonical Autophagy
Author: Giulia Petroni,Lorenzo Galluzzi
Publsiher: Academic Press
Total Pages: 182
Release: 2021-05-01
ISBN 10: 0128209119
ISBN 13: 9780128209110
Language: EN, FR, DE, ES & NL

Non Canonical Autophagy Book Review:

Non-canonical Autophagy: Mechanisms and Pathophysiological Implications outlines the differences between ‘canonical’ and ‘non-canonical’ forms of autophagy, highlighting the discoveries concerning the molecular mechanisms underlying these unconventional forms of autophagy and the advancements in pathophysiological features of ‘non-canonical’ autophagy. The book discusses all forms of ‘non-canonical’ autophagy and the complexity of autophagy-dependent cell death. Readers will gain a better understanding of mechanisms underlying ‘non-canonical’ autophagy so that they can interpret the biological effects of autophagy correctly and identify reliable, novel and effective treatment strategies. Presents the most advanced information surrounding the molecular mechanisms underlying non-canonical autophagy Outlines the increasing evidence regarding the involvement of non-canonical autophagy in multiple physiological and pathological processes Discusses the therapeutic potential of autophagy modulators and the obstacles that have limited their development

A Study on Non canonical Autophagy Signalling

A Study on Non canonical Autophagy Signalling
Author: Cansu Karabiyik
Publsiher: Unknown
Total Pages: 135
Release: 2021
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1259539942
Language: EN, FR, DE, ES & NL

A Study on Non canonical Autophagy Signalling Book Review:

ATG8 Regulation and Function in Non canonical Autophagy

ATG8 Regulation and Function in Non canonical Autophagy
Author: Katherine Sloan
Publsiher: Unknown
Total Pages: 135
Release: 2020
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1259549236
Language: EN, FR, DE, ES & NL

ATG8 Regulation and Function in Non canonical Autophagy Book Review:

Regulation of B Cell Responses by Non canonical Autophagy

Regulation of B Cell Responses by Non canonical Autophagy
Author: Paula Maldonado Villavicencio
Publsiher: Unknown
Total Pages: 135
Release: 2019
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1197752180
Language: EN, FR, DE, ES & NL

Regulation of B Cell Responses by Non canonical Autophagy Book Review:

Novel Mechanisms of Atg16L1 Recruitment in Non canonical Autophagy

Novel Mechanisms of Atg16L1 Recruitment in Non canonical Autophagy
Author: Katherine Anne Fletcher
Publsiher: Unknown
Total Pages: 135
Release: 2019
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1104602716
Language: EN, FR, DE, ES & NL

Novel Mechanisms of Atg16L1 Recruitment in Non canonical Autophagy Book Review:

Canonical and Non canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System

Canonical and Non canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System
Author: Rebecca Bohn
Publsiher: Unknown
Total Pages: 135
Release: 2017
ISBN 10: 1928374650XXX
ISBN 13: OCLC:987368480
Language: EN, FR, DE, ES & NL

Canonical and Non canonical Autophagy Modulation in Human Primary Macrophages and Its Effect on the Adaptive Immune System Book Review:

Non canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation

Non canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation
Author: Christian Wolfgang Keller
Publsiher: Unknown
Total Pages: 135
Release: 2017
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1004342411
Language: EN, FR, DE, ES & NL

Non canonical Functions on the Essential Autophagy Protein ATG5 in Antigen Processing and Presentation Book Review:

The Non canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones

The Non canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones
Author: Anonim
Publsiher: Unknown
Total Pages: 47
Release: 2016
ISBN 10: 1928374650XXX
ISBN 13: OCLC:976434208
Language: EN, FR, DE, ES & NL

The Non canonical Role of Autophagy Components in the Secretion of Neural Peptide Hormones Book Review:

The canonical autophagy pathway has primarily been described as a degradative mechanism, which clears the cell of old damaged organelles, protein aggregates and pathogens. Central to the pathway is the de novo formation of a vesicle structure called the autophagosome, which fuses with lysosomes to degrade its content. The Atg8a/MAP1-LC3 protein family is essential for the formation of the autophagosome, and Atg8a mutations result in a variety of defects related to decreased autophagic function. Recently, we have observed a phenotype in Atg8a mutant Drosophila that is consistent with secretory defects of the peptide hormone Bursicon, which is responsible for wing expansion and cuticle hardening upon eclosion. This observation is in accordance with other recent findings which show that components of the autophagy pathway are also involved in the secretion of bioactive molecules. However, the intersection of autophagy and secretory pathways is not yet fully understood. Here, we show that along with Bursicon two additional peptide hormones are differentially secreted and show impaired hemolymph profiles when autophagic function is lowered in the fly nervous system. This includes the release of the pigment dispersing factor (PDF, circadian cycle) and the mesencephalic astrocyte-derived neurotrophic factor (dMANF, stress response), which is highlighted by the aberrant sleep-circadian behaviors (PDF) and trauma-mediated sensitivity (MANF) associated with Atg8a1 mutant flies. Based on the Bursicon wing phenotype, we conducted a secretion-based screen using the GAL4/UAS-dsRNAi knockdown system and identified Atg8a and other autophagy components involved with organelle initiation and membrane expansion that show impaired Bursicon release upon knockdown. Furthermore, this did not include genes involved with selective autophagy (aggrephagy) or endosomal-lysosomal trafficking. Findings from this research will have broad implications toward understanding complex secretory defects and the intersection of autophagy with other vesicle trafficking pathways.

Examining the Role of Autophagy in Osteoclast Function

Examining the Role of Autophagy in Osteoclast Function
Author: Anh Nhi Tran
Publsiher: Unknown
Total Pages: 135
Release: 2018
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1064654562
Language: EN, FR, DE, ES & NL

Examining the Role of Autophagy in Osteoclast Function Book Review:

Autophagy

Autophagy
Author: Nicholas Ktistakis,Oliver Florey
Publsiher: Humana Press
Total Pages: 741
Release: 2019-01-05
ISBN 10: 9781493988723
ISBN 13: 1493988727
Language: EN, FR, DE, ES & NL

Autophagy Book Review:

This volume details a comprehensive and extensive set of protocols for the study of autophagy in vitro and in vivo. Chapters focus on mammals, various model organisms, and provide protocols for the study of autophagy-related processes outside of the canonical autophagy pathways. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Autophagy: Methods and Protocols aims to ensure successful results in the further study of this vital field.

Cell Death

Cell Death
Author: Tobias Ntuli
Publsiher: BoD – Books on Demand
Total Pages: 446
Release: 2015-12-16
ISBN 10: 9535122363
ISBN 13: 9789535122364
Language: EN, FR, DE, ES & NL

Cell Death Book Review:

This book is a collection of selected and relevant research, concerning the developments within the Cell Death field of study. Each contribution comes as a separate chapter complete in itself but directly related to the books topics and objectives. The target audience comprises scholars and specialists in the field.

Membrane Biogenesis

Membrane Biogenesis
Author: Jos A.F. Op den Kamp
Publsiher: Springer Science & Business Media
Total Pages: 477
Release: 2013-06-29
ISBN 10: 3642731848
ISBN 13: 9783642731846
Language: EN, FR, DE, ES & NL

Membrane Biogenesis Book Review:

Many individual aspects of the dynamics and assembly of biological membranes have been studied in great detail. Cell biological approaches, advanced genetics, biophysics and biochemistry have greatly contributed to an increase in our knowledge in this field.lt is obvious however, that the three major membrane constituents - lipids, proteins and carbohydrates- are studied, in most cases separately and that a coherent overview of the various aspects of membrane biogenesis is not readily available. The NATO Advanced Study Institute on "New Perspectives in the Dynamics of Assembly of Biomembranes" intended to provide such an overview: it was set up to teach students and specialists the achievements obtained in the various research areas and to try and integrate the numerous aspects of membrane assembly into a coherent framework. The articles in here reflect this. Statting with detailed contributions on phospholipid structure, dynamics, organization and biogenesis, an up to date overview of the basic, lipidic backbone of biomembranes is given. Extensive progress is made in the research on membrane protein biosynthesis. In particular the post- and co-translational modification processes of proteins, the mechanisms of protein translocation and the sorting mechanisms which are necessary to direct proteins to their final, intra - or extracellular destination have been characterized in detail. Modern genetic approaches were indispensable in this research area: gene cloning, hybrid protein construction, site directed mutagenesis and sequencing techniques elucidated many functional aspects of specific nucleic acid and amino acid sequences.

Tumor Cell Metabolism and Autophagy as Therapeutic Targets

Tumor Cell Metabolism and Autophagy as Therapeutic Targets
Author: Carlos Pérez-Plasencia,Nadia Judith Jacobo-Herrera,Luis Enrique Gomez-Quiroz
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-02-24
ISBN 10: 2889665003
ISBN 13: 9782889665006
Language: EN, FR, DE, ES & NL

Tumor Cell Metabolism and Autophagy as Therapeutic Targets Book Review:

Autophagy Regulation of Innate Immunity

Autophagy Regulation of Innate Immunity
Author: Jun Cui
Publsiher: Springer Nature
Total Pages: 203
Release: 2019-11-14
ISBN 10: 981150606X
ISBN 13: 9789811506062
Language: EN, FR, DE, ES & NL

Autophagy Regulation of Innate Immunity Book Review:

This book discusses novel concepts and discoveries concerning the regulation of innate immunity by autophagy and autophagy-related proteins. In the past decade, there have been major advances in our understanding of the molecular mechanisms of autophagy and its physiological functions. This book highlights emerging studies on the underlying mechanisms of autophagy regulation of innate immunity, including inflammation, antiviral immunity and anti-bacterial responses and the signaling pathways that prompt or inhibit the initiation and progression of related diseases. It also offers new ideas and strategies for future drugs based on manipulating autophagy, especially selective autophagy mediated by cargo receptors. Providing a comprehensive overview of the autophagy regulation of innate immunity, it is a valuable resource for graduate students and researchers in the fields of immunology, cell biology and translational medicine.

Autophagy in Health and Disease

Autophagy in Health and Disease
Author: Roberta A. Gottlieb
Publsiher: Academic Press
Total Pages: 227
Release: 2012-10-16
ISBN 10: 0123851017
ISBN 13: 9780123851017
Language: EN, FR, DE, ES & NL

Autophagy in Health and Disease Book Review:

Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information. Discusses current understanding of the roles of autophagy in health and disease Covers the background of autophagy, the development of tools and therapeutics to measure and modulate autophagy, and autophagy in tissues and disease processes Features an accompanying website with figures and tables

Autophagy in Current Trends in Cellular Physiology and Pathology

Autophagy in Current Trends in Cellular Physiology and Pathology
Author: Nikolai Gorbunov,E. Marion Schneider
Publsiher: BoD – Books on Demand
Total Pages: 526
Release: 2016-11-10
ISBN 10: 9535127268
ISBN 13: 9789535127260
Language: EN, FR, DE, ES & NL

Autophagy in Current Trends in Cellular Physiology and Pathology Book Review:

Autophagy in Current Trends in Cellular Physiology and Pathology is addressed to one of the fundamental molecular mechanisms - autophagy- evolutionarily adopted by cells for processing of unnecessary or malfunctioned constituents and shaping intracellular structures, adjusting them to environmental conditions, aging, disease, neoplasia, and damages over their life period. Particular attention is paid to autophagy-mediated barrier processes of selective sequestration and recycling of impaired organelles and degradation of invading microorganisms, that is, the processes sustaining intrinsic resistance to stress, tissue degeneration, toxic exposures, and infections. The presented topics encompass personal experience and visions of the chapter contributors and the editors; the book chapters include a broad analysis of literature on biology of autophagy.

Autophagy of the Nervous System

Autophagy of the Nervous System
Author: Zhenyu Yue,Charleen T. Chu
Publsiher: World Scientific
Total Pages: 426
Release: 2012
ISBN 10: 9814350443
ISBN 13: 9789814350440
Language: EN, FR, DE, ES & NL

Autophagy of the Nervous System Book Review:

What is autophagy? Why would neurons or other brain cells digest parts of themselves through autophagy? How can autophagy save the lives of cells under some conditions, but act as a culprit or accomplice to cell death in others? How does dysfunction of autophagy contribute to neurological diseases and can it be repaired or restored? This book addresses these questions and provide an expert view of the emerging concepts in autophagy research, focusing on autophagic processes and regulation in neurons. Current experimental evidence for both evolutionarily conserved and specialized regulatory mechanisms for autophagy in the mammalian nervous system will be presented. Advances in our understanding of the complex interplay of autophagy induction and downregulation will be discussed in relation to the critical balance needed to modulate neuroprotection versus neurodegeneration in the context of neurological diseases including Alzheimer's, Parkinson's, Huntington's, ischemic-hypoxic and lysosomal diseases.

Looking Beyond Pattern Recognition Perturbations in Cellular Homeostasis and Metabolism as Emerging Regulators of Dendritic Cell Function

Looking Beyond Pattern Recognition  Perturbations in Cellular Homeostasis and Metabolism as Emerging Regulators of Dendritic Cell Function
Author: Fabiola Osorio,Bart Everts
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2019-12-09
ISBN 10: 2889632288
ISBN 13: 9782889632282
Language: EN, FR, DE, ES & NL

Looking Beyond Pattern Recognition Perturbations in Cellular Homeostasis and Metabolism as Emerging Regulators of Dendritic Cell Function Book Review:

Autophagy in Autoimmunity

Autophagy in Autoimmunity
Author: Xu-jie Zhou,Panayotis Verginis,Jennifer Martinez,Marko Radic
Publsiher: Frontiers Media SA
Total Pages: 161
Release: 2019-05-15
ISBN 10: 2889458121
ISBN 13: 9782889458127
Language: EN, FR, DE, ES & NL

Autophagy in Autoimmunity Book Review:

Regulated Cell Death Part B

Regulated Cell Death Part B
Author: Anonim
Publsiher: Academic Press
Total Pages: 352
Release: 2014-07-24
ISBN 10: 0128016191
ISBN 13: 9780128016190
Language: EN, FR, DE, ES & NL

Regulated Cell Death Part B Book Review:

Regulated Cell Death Part A & Part B of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in biomineralization science Regulated Cell Death Part A & Part B contains sections on such topics as apoptosis focusing on the important areas of intrinsic pathway, extrinsic pathway, caspases, cellular assays and post-apoptotic effects and model organisms; as well as topics on necroptosis and screening approaches