NMR Spectroscopy in Pharmaceutical Analysis

NMR Spectroscopy in Pharmaceutical Analysis
Author: Iwona Wawer,Bernd Diehl
Publsiher: Elsevier
Total Pages: 528
Release: 2017-07-07
ISBN 10: 008095152X
ISBN 13: 9780080951522
Language: EN, FR, DE, ES & NL

NMR Spectroscopy in Pharmaceutical Analysis Book Review:

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership

NMR Spectroscopy in Pharmaceutical Analysis

NMR Spectroscopy in Pharmaceutical Analysis
Author: Iwona Wawer,Bernd Diehl
Publsiher: Elsevier
Total Pages: 528
Release: 2008-08-22
ISBN 10: 0080558194
ISBN 13: 9780080558196
Language: EN, FR, DE, ES & NL

NMR Spectroscopy in Pharmaceutical Analysis Book Review:

For almost a decade, quantitative NMR spectroscopy (qNMR) has been established as valuable tool in drug analysis. In all disciplines, i. e. drug identification, impurity profiling and assay, qNMR can be utilized. Separation techniques such as high performance liquid chromatography, gas chromatography, super fluid chromatography and capillary electrophoresis techniques, govern the purity evaluation of drugs. However, these techniques are not always able to solve the analytical problems often resulting in insufficient methods. Nevertheless such methods find their way into international pharmacopoeias. Thus, the aim of the book is to describe the possibilities of qNMR in pharmaceutical analysis. Beside the introduction to the physical fundamentals and techniques the principles of the application in drug analysis are described: quality evaluation of drugs, polymer characterization, natural products and corresponding reference compounds, metabolism, and solid phase NMR spectroscopy for the characterization drug substances, e.g. the water content, polymorphism, and drug formulations, e.g. tablets, powders. This part is accompanied by more special chapters dealing with representative examples. They give more detailed information by means of concrete examples. Combines theory, techniques, and concrete applications—all of which closely resemble the laboratory experience Considers international pharmacopoeias, addressing the concern for licensing Features the work of academics and researchers, appealing to a broad readership

NMR Spectroscopy in Drug Development and Analysis

NMR Spectroscopy in Drug Development and Analysis
Author: Ulrike Holzgrabe,Iwona Wawer,Bernd Diehl
Publsiher: John Wiley & Sons
Total Pages: 312
Release: 2008-07-11
ISBN 10: 352761365X
ISBN 13: 9783527613656
Language: EN, FR, DE, ES & NL

NMR Spectroscopy in Drug Development and Analysis Book Review:

Since the development of the NMR spectrometer in the 1950s, NMR spectra have been widely used for the elucidation of the 2D structure of newly synthesized and natural compounds. In the 1980s, the high-resolution NMR spectrometer (> 300 Mhz) and 2D experiments were introduced, which opens up the possibility to determine the 3D structure of large molecules, especially biomolecules. However, NMR spectroscopy has been rarely applied to drug analysis. This book illustrates the power and versatility of NMR spectroscopy in the determination of impurities in and the content of drugs, the composition of polymer excipients, the characterization of isomeric drug mixtures, the complexity of drugs with small-size components or ions, and the behavior of drugs in acid and basic solution. In addition, NMR spectroscopy and especially the hyphenated technique with HPLC is shown to be a powerful tool to measure a drug and its metabolites in various body fluids. The solid state NMR technique can give information on the structure, especially the conformation of drugs and excipients in drug formulations. Recently, SAR by NMR, introduced by Fesik, impressively demonstrated the potential of NMR spectroscopy in drug development and in the characterization of the interaction between large molecules and ligands. The complexation between proteins, lipids and cyclodextrins with drugs is described. Finally, NMR imaging (MRI and MRS) can be used to characterize the liberation of drugs from a drug formulation. Furthermore, the distribution of substances in plants, in animals, in tissues and in humans can be visualized by imaging. In short, this book covers all aspects of drug analysis.

NMR in Pharmaceutical Science

NMR in Pharmaceutical Science
Author: Robin K. Harris
Publsiher: John Wiley & Sons
Total Pages: 504
Release: 2015-09-28
ISBN 10: 1118660250
ISBN 13: 9781118660256
Language: EN, FR, DE, ES & NL

NMR in Pharmaceutical Science Book Review:

NMR in Pharmaceutical Sciences is intended to be a comprehensive source of information for the many individuals that utilize MR in studies of relevance to the pharmaceutical sector. The book is intended to educate and inform those who develop and apply MR approaches within the wider pharmaceutical environment, emphasizing the toolbox that is available to spectroscopists and radiologists. This book is structured on the key processes in drug discovery, development and manufacture, but underpinned by an understanding of fundamental NMR principles and the unique contribution that NMR (including MRI) can provide. After an introductory chapter, which constitutes an overview, the content is organised into five sections. The first section is on the basics of NMR theory and relevant experimental methods. The rest follow a sequence based on the chronology of drug discovery and development, firstly 'Idea to Lead' then 'Lead to Drug Candidate', followed by 'Clinical Development', and finally 'Drug Manufacture'. The thirty one chapters cover a vast range of topics from analytical chemistry, including aspects involved in regulatory matters and in the prevention of fraud, to clinical imaging studies. Whilst this comprehensive volume will be essential reading for many scientists based in pharmaceutical and related industries, it should also be of considerable value to a much wider range of academic scientists whose research is related to the various aspects of pharmaceutical R&D; for them it will supply vital understanding of pharmaceutical industrial concerns and the basis of key decision making processes. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of Magnetic Resonance) publishes a wide range of online articles on all aspects of magnetic resonance in physics, chemistry, biology and medicine. The existence of this large number of articles, written by experts in various fields, is enabling the publication of a series of eMagRes Handbooks on specific areas of NMR and MRI. The chapters of each of these handbooks will comprise a carefully chosen selection of eMagRes articles. In consultation with the eMagRes Editorial Board, the eMagRes handbooks are coherently planned in advance by specially-selected Editors, and new articles are written to give appropriate complete coverage. The handbooks are intended to be of value and interest to research students, postdoctoral fellows and other researchers learning about the scientific area in question and undertaking relevant experiments, whether in academia or industry. Have the content of this handbook and the complete content of eMagRes at your fingertips! Visit: www.wileyonlinelibrary.com/ref/eMagRes

Applications of NMR Spectroscopy Vol 6

Applications of NMR Spectroscopy  Vol  6
Author: Atta-ur- Rahman,M. Iqbal Choudhary
Publsiher: Bentham Science Publishers
Total Pages: 240
Release: 2017-12-04
ISBN 10: 1681084392
ISBN 13: 9781681084398
Language: EN, FR, DE, ES & NL

Applications of NMR Spectroscopy Vol 6 Book Review:

Applications of NMR Spectroscopy is a book series devoted to publishing the latest advances in the applications of nuclear magnetic resonance (NMR) spectroscopy in various fields of organic chemistry, biochemistry, health and agriculture. The sixth volume of the series features reviews focusing on NMR spectroscopic techniques for studying tautomerism, applications in medical diagnosis, in food chemistry and identifying secondary metabolites.

Spectroscopic Analyses

Spectroscopic Analyses
Author: Eram Sharmin,Fahmina Zafar
Publsiher: BoD – Books on Demand
Total Pages: 240
Release: 2017-12-06
ISBN 10: 9535136275
ISBN 13: 9789535136279
Language: EN, FR, DE, ES & NL

Spectroscopic Analyses Book Review:

The book presents developments and applications of these methods, such as NMR, mass, and others, including their applications in pharmaceutical and biomedical analyses. The book is divided into two sections. The first section covers spectroscopic methods, their applications, and their significance as characterization tools; the second section is dedicated to the applications of spectrophotometric methods in pharmaceutical and biomedical analyses. This book would be useful for students, scholars, and scientists engaged in synthesis, analyses, and applications of materials/polymers.

NMR Spectroscopy

NMR Spectroscopy
Author: Harald Günther
Publsiher: John Wiley & Sons
Total Pages: 734
Release: 2013-12-13
ISBN 10: 3527674772
ISBN 13: 9783527674770
Language: EN, FR, DE, ES & NL

NMR Spectroscopy Book Review:

Nuclear magnetic resonance (NMR) spectroscopy is one of the most powerful and widely used techniques in chemical research for investigating structures and dynamics of molecules. Advanced methods can even be utilized for structure determinations of biopolymers, for example proteins or nucleic acids. NMR is also used in medicine for magnetic resonance imaging (MRI). The method is based on spectral lines of different atomic nuclei that are excited when a strong magnetic field and a radiofrequency transmitter are applied. The method is very sensitive to the features of molecular structure because also the neighboring atoms influence the signals from individual nuclei and this is important for determining the 3D-structure of molecules. This new edition of the popular classic has a clear style and a highly practical, mostly non-mathematical approach. Many examples are taken from organic and organometallic chemistry, making this book an invaluable guide to undergraduate and graduate students of organic chemistry, biochemistry, spectroscopy or physical chemistry, and to researchers using this well-established and extremely important technique. Problems and solutions are included.

Pharmaceutical Analysis

Pharmaceutical Analysis
Author: David C Lee,Michael L. Webb
Publsiher: John Wiley & Sons
Total Pages: 384
Release: 2009-02-12
ISBN 10: 1405172991
ISBN 13: 9781405172998
Language: EN, FR, DE, ES & NL

Pharmaceutical Analysis Book Review:

The use of analytical sciences in the discovery, development andmanufacture of pharmaceuticals is wide-ranging. From the analysisof minute amounts of complex biological materials to the qualitycontrol of the final dosage form, the use of analytical technologycovers an immense range of techniques and disciplines. This book concentrates on the analytical aspects of drugdevelopment and manufacture, focusing on the analysis of the activeingredient or drug substance. It provides those joining theindustry or other areas of pharmaceutical research with a source ofreference to a broad range of techniques and their applications,allowing them to choose the most appropriate analytical techniquefor a particular purpose. The volume is directed at analytical chemists, industrialpharmacists, organic chemists, pharmaceutical chemists andbiochemists.

Structure activity Relationship Studies in Drug Development by NMR Spectroscopy

Structure activity Relationship Studies in Drug Development by NMR Spectroscopy
Author: Atta-ur- Rahman,M. Iqbal Choudhary
Publsiher: Bentham Science Publishers
Total Pages: 214
Release: 2011
ISBN 10: 1608051641
ISBN 13: 9781608051649
Language: EN, FR, DE, ES & NL

Structure activity Relationship Studies in Drug Development by NMR Spectroscopy Book Review:

"NMR (Nuclear Magnetic Resonance) Spectroscopy has found significant applications in drug discovery based on its capacity to map molecular interactions at the atomic level. Chemical shifts, cross relaxation, and exchange of protons are among the NMR parame"

Coupling of Capillary Electrophoresis with Nuclear Magnetic Resonance Spectroscopy for the Analysis of Pharmaceutical and Environmental Relevant Compo

Coupling of Capillary Electrophoresis with Nuclear Magnetic Resonance Spectroscopy for the Analysis of Pharmaceutical and Environmental Relevant Compo
Author: Joana Diekmann
Publsiher: GRIN Verlag
Total Pages: 116
Release: 2011-04
ISBN 10: 3640873599
ISBN 13: 9783640873593
Language: EN, FR, DE, ES & NL

Coupling of Capillary Electrophoresis with Nuclear Magnetic Resonance Spectroscopy for the Analysis of Pharmaceutical and Environmental Relevant Compo Book Review:

Master's Thesis from the year 2009 in the subject Chemistry - Analytical Chemistry, grade: 1,0, University of Hannover (Anorganische Chemie), language: English, comment: This Master Thesis was awarded with the "E.ON Future Award 2010" and it was carried out at the Leibniz University Hannover, Faculty of Natural Sciences, Institute for Inorganic Chemistry, Department of Analytical Chemistry, in cooperation with the Lawrence Livermore National Laboratory, Physical and Life Sciences Directorate, Livermore, CA, USA., abstract: Separation and identification of mass-limited chemical samples is the key to understand the complex nature of pharmaceutical and environmental systems. High efficiency separation techniques, such as capillary electrophoresis (CE), coupled to a non-destructive, information-rich detection, such as nuclear magnetic resonance (NMR) spectroscopy, have revolutionized the ability to separate and identify components in small sample volumes. Using this hyphenated system, structure elucidation of analytes separated during an electrophoretic process can be performed using NMR as an on-line detector. Although sensitivity remains an issue for on-line NMR detection, capillary NMR spectroscopy using microcoils has emerged as a major breakthrough for increasing the mass-sensitivity of NMR spectroscopy, because the limit of detection is proportional to the coil diameter. A further development is the miniaturization of the magnet enabling the possibility of a truly portable NMR system. This portable, low-cost NMR sensor, coupled to the rapid CE separation system could enable high-throughput and on-site identification of nanoliter amounts of solution. Furthermore, CE can provide on-line pre-concentration via electrokinetic injection or other stacking techniques to increase the sample concentration. In this research, coupling CE to a laboratory-scale NMR and to a portable NMR system are investigated, with the emphasis on the development of the miniaturized system.

NMR Spectroscopy

NMR Spectroscopy
Author: Myrna J. Simpson,Andre J. Simpson
Publsiher: John Wiley & Sons
Total Pages: 448
Release: 2014-06-12
ISBN 10: 111861643X
ISBN 13: 9781118616437
Language: EN, FR, DE, ES & NL

NMR Spectroscopy Book Review:

The challenges faced by environmental scientists today are vast,complex, and multi-faceted. For instance, predicting the fateof an environmental pollutant or understanding ecosystem responsesto climate change, necessitate a firm understanding of molecularstructure and dynamics of environmental media as well as thecomponents that exist and interact within this media. Furthermore, linking information obtained at the molecular-scale toecosystem-level processes is a major pursuit of modernenvironmental research. As such, NMR spectroscopy and itsscalability from the molecular-scale to the macroscopic-scale, isfacilitating rapid growth in environmental science. In addition,the versatility of NMR spectroscopy has resulted in the developmentand implementation of different types of NMR techniques to examinethe structure of various types of environmental samples, living andnon-living, as well as the study of critical environmentalprocesses. This comprehensive handbook is a collection of chapters thatspan from methods to how NMR is used in environmental research togain insight into various ecosystem properties. It is organized into three parts: Part A focuses on methods used in environmental NMRwhich span from solution-state to magnetic resonanceimaging. Part B emphasizes how NMR spectroscopy plays anessential role in understanding various types of environmentalcomponents and related processes, including different forms oforganic matter found in soil, water, and air as well as how NMR isused to probe the fate of water, organic pollutants, and metals inthe environment. Part C focuses on the growing field of environmentalmetabolomics which uses NMR as its main discoveryplatform. This volume highlights the immense potential of NMR spectroscopyto expand our fundamental understanding of environmental processesand how it will continue to do so well into the future. About eMagRes Handbooks eMagRes (formerly the Encyclopedia of MagneticResonance) publishes a wide range of online articles on allaspects of magnetic resonance in physics, chemistry, biology andmedicine. The existence of this large number of articles, writtenby experts in various fields, is enabling the publication of aseries of eMagRes Handbooks on specific areas of NMR and MRI. Thechapters of each of these handbooks will comprise a carefullychosen selection of eMagRes articles. In consultation with theeMagRes Editorial Board, the eMagRes handbooks arecoherently planned in advance by specially-selected Editors, andnew articles are written to give appropriate complete coverage. Thehandbooks are intended to be of value and interest to researchstudents, postdoctoral fellows and other researchers learning aboutthe scientific area in question and undertaking relevantexperiments, whether in academia or industry. Have the content of this handbook and the complete content ofeMagRes at your fingertips! Visit: ahref="http://www.wileyonlinelibrary.com/ref/eMagRes"www.wileyonlinelibrary.com/ref/eMagRes/a

Nuclear Magnetic Resonance Spectroscopy

Nuclear Magnetic Resonance Spectroscopy
Author: Joseph B. Lambert,Eugene P. Mazzola,Clark D. Ridge
Publsiher: Wiley
Total Pages: 480
Release: 2019-01-04
ISBN 10: 1119295238
ISBN 13: 9781119295235
Language: EN, FR, DE, ES & NL

Nuclear Magnetic Resonance Spectroscopy Book Review:

Combines clear and concise discussions of key NMR concepts with succinct and illustrative examples Designed to cover a full course in Nuclear Magnetic Resonance (NMR) Spectroscopy, this text offers complete coverage of classic (one-dimensional) NMR as well as up-to-date coverage of two-dimensional NMR and other modern methods. It contains practical advice, theory, illustrated applications, and classroom-tested problems; looks at such important ideas as relaxation, NOEs, phase cycling, and processing parameters; and provides brief, yet fully comprehensible, examples. It also uniquely lists all of the general parameters for many experiments including mixing times, number of scans, relaxation times, and more. Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition begins by introducing readers to NMR spectroscopy - an analytical technique used in modern chemistry, biochemistry, and biology that allows identification and characterization of organic, and some inorganic, compounds. It offers chapters covering: Experimental Methods; The Chemical Shift; The Coupling Constant; Further Topics in One-Dimensional NMR Spectroscopy; Two-Dimensional NMR Spectroscopy; Advanced Experimental Methods; and Structural Elucidation. Features classical analysis of chemical shifts and coupling constants for both protons and other nuclei, as well as modern multi‐pulse and multi-dimensional methods Contains experimental procedures and practical advice relative to the execution of NMR experiments Includes a chapter-long, worked-out problem that illustrates the application of nearly all current methods Offers appendices containing the theoretical basis of NMR, including the most modern approach that uses product operators and coherence-level diagrams By offering a balance between volumes aimed at NMR specialists and the structure-determination-only books that focus on synthetic organic chemists, Nuclear Magnetic Resonance Spectroscopy: An Introduction to Principles, Applications, and Experimental Methods, 2nd Edition is an excellent text for students and post-graduate students working in analytical and bio-sciences, as well as scientists who use NMR spectroscopy as a primary tool in their work.

Applied NMR Spectroscopy for Chemists and Life Scientists

Applied NMR Spectroscopy for Chemists and Life Scientists
Author: Oliver Zerbe,Simon Jurt
Publsiher: John Wiley & Sons
Total Pages: 548
Release: 2013-11-26
ISBN 10: 3527677836
ISBN 13: 9783527677832
Language: EN, FR, DE, ES & NL

Applied NMR Spectroscopy for Chemists and Life Scientists Book Review:

From complex structure elucidation to biomolecular interactions - this applicationoriented textbook covers both theory and practice of modern NMR applications. Part one sets the stage with a general description of NMR introducing important parameters such as the chemical shift and scalar or dipolar couplings. Part two describes the theory behind NMR, providing a profound understanding of the involved spin physics, deliberately kept shorter than in other NMR textbooks, and without a rigorous mathematical treatment of all the physico-chemical computations. Part three discusses technical and practical aspects of how to use NMR. Important phenomena such as relaxation, exchange, or the nuclear Overhauser effects and the methods of modern NMR spectroscopy including multidimensional experiments, solid state NMR, and the measurement of molecular interactions are the subject of part four. The final part explains the use of NMR for the structure determination of selected classes of complex biomolecules, from steroids to peptides or proteins, nucleic acids, and carbohydrates. For chemists as well as users of NMR technology in the biological sciences.

Disordered Pharmaceutical Materials

Disordered Pharmaceutical Materials
Author: Marc Descamps
Publsiher: John Wiley & Sons
Total Pages: 544
Release: 2016-03-28
ISBN 10: 3527652728
ISBN 13: 9783527652723
Language: EN, FR, DE, ES & NL

Disordered Pharmaceutical Materials Book Review:

A one-stop resource for researchers, developers, and post graduate students in pharmaceutical science. This handbook and ready reference provides detailed, but not overloaded information -- presenting the topic without unnecessarily complex formalism. As such, it gives a systematic and coherent overview of disordered materials for pharmaceutical applications, covering fundamental aspects, as well as preparation and characterization techniques for the target-oriented development of drug delivery systems based on disordered crystals and amorphous solids. Special attention is paid to examine the different facets and levels of disorder in their structural and dynamic aspects as well as the effect of disorder on dissolution and stability. Chapters on processing induced disorder and on patenting issues round off the book. As a result the book helps overcoming the challenges of using these materials in the pharmaceutical industry. For pharmaceutical and medicinal chemists, materials scientists, clinical physicists, and pharmaceutical laboratories looking to make better and more potent pharmaceuticals.

Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences

Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences
Author: Mark Stauffer
Publsiher: BoD – Books on Demand
Total Pages: 440
Release: 2016-10-05
ISBN 10: 9535126806
ISBN 13: 9789535126805
Language: EN, FR, DE, ES & NL

Applications of Molecular Spectroscopy to Current Research in the Chemical and Biological Sciences Book Review:

The goal of this book is to present an overview of applications of molecular spectroscopy to investigations in organic and inorganic materials, foodstuffs, biosamples and biomedicine, and novel characterization and quantitation methods. This text is a compilation of selected research articles and reviews covering current efforts in various applications of molecular spectroscopy. Sections 1 and 2 deal, respectively, with spectroscopic studies of inorganic and organic materials. Section 3 provides applications of molecular spectroscopy to biosamples and biomedicine. Section 4 explores spectroscopic characterization and quantitation of foods and beverages. Lastly, Section 5 presents research on novel spectroscopic methodologies. Overall, this book should be a great source of scientific information for anyone involved in characterization, quantitation, and method development.

New Applications of NMR in Drug Discovery and Development

New Applications of NMR in Drug Discovery and Development
Author: Leoncio Garrido,Nicolau Beckmann,William Price
Publsiher: Royal Society of Chemistry
Total Pages: 565
Release: 2013-07-24
ISBN 10: 1849734445
ISBN 13: 9781849734448
Language: EN, FR, DE, ES & NL

New Applications of NMR in Drug Discovery and Development Book Review:

This book presents a review of new developments in NMR for applications in medicinal chemistry and drug discovery. The contents will focus on consolidated and emerging techniques and methods that are at present not widely applied, however it is considered that they could contribute to the advancement of drug discovery and drug development.

Process Analytical Technology

Process Analytical Technology
Author: Katherine A. Bakeev
Publsiher: John Wiley & Sons
Total Pages: 472
Release: 2008-04-15
ISBN 10: 140517319X
ISBN 13: 9781405173193
Language: EN, FR, DE, ES & NL

Process Analytical Technology Book Review:

The use of real or near real time measurement of chemical production process parameters as the basis for achieving control or optimisation of a manufacturing process has wide application in the petrochemical, food and chemical industries. Process analytical chemistry (PAC), or process analytical technology (PAT) as it has recently been called, is now being deployed in the pharmaceutical industry, where it is seen as a technology that can help companies to improve their conformity with manufacturing compliance regulations. The objective of this book is to provide a starting point for implementing process analytical chemistry tools in process monitoring applications or as part of a total quality management system. Written from the perspective of the spectroscopist required to implant PAT tools in a process environment, attention is focussed on measurements that are made "in process" at-line or off-line, providing data on product during manufacture. With chapters covering the key spectroscopic tools, their applications in the pharmaceutical and chemical industries and basic chemometrics, the novice can quickly develop a sound understanding of the most practical technologies and applications. Implementation strategies are fully covered and address some of the critical issues that need to be tackled when setting up a PAT project – including choosing a project with a sound business justification in the first place.

Natural Products Analysis

Natural Products Analysis
Author: Vladimir Havlicek,Jaroslav Spizek
Publsiher: John Wiley & Sons
Total Pages: 624
Release: 2014-09-17
ISBN 10: 1118876024
ISBN 13: 9781118876022
Language: EN, FR, DE, ES & NL

Natural Products Analysis Book Review:

This book highlights analytical chemistry instrumentation andpractices applied to the analysis of natural products and theircomplex mixtures, describing techniques for isolating andcharacterizing natural products. • Applies analytical techniques to natural productsresearch – an area of critical importance to drugdiscovery • Offers a one-stop shop for most analytical methods:x-ray diffraction, NMR analysis, mass spectrometry, and chemicalgenetics • Includes coverage of natural products basics andhighlights antibacterial research, particularly important asefforts to combat drug resistance gain prominence • Covers instrumental techniques with enough detail forboth current practitioners and beginning researchers

Essentials of Pharmaceutical Analysis

Essentials of Pharmaceutical Analysis
Author: Muhammad Sajid Hamid Akash,Kanwal Rehman
Publsiher: Springer Nature
Total Pages: 222
Release: 2019-12-17
ISBN 10: 9811515476
ISBN 13: 9789811515477
Language: EN, FR, DE, ES & NL

Essentials of Pharmaceutical Analysis Book Review:

Recent advances in the pharmaceutical sciences and biotechnology have facilitated the production, design, formulation and use of various types of pharmaceuticals and biopharmaceuticals. This book provides detailed information on the background, basic principles, and components of techniques used for the analysis of pharmaceuticals and biopharmaceuticals. Focusing on those analytical techniques that are most frequently used for pharmaceuticals, it classifies them into three major sections and 19 chapters, each of which discusses a respective technique in detail. Chiefly intended for graduate students in the pharmaceutical sciences, the book will familiarize them with the components, working principles and practical applications of these indispensable analytical techniques.

Multidimensional Solid State NMR and Polymers

Multidimensional Solid State NMR and Polymers
Author: Klaus Schmidt-Rohr,Hans Wolfgang Spiess
Publsiher: Elsevier
Total Pages: 496
Release: 2012-12-02
ISBN 10: 0080925626
ISBN 13: 9780080925622
Language: EN, FR, DE, ES & NL

Multidimensional Solid State NMR and Polymers Book Review:

NMR spectroscopy is the most valuable and versatile analytical tool in chemistry. While excellent monographs exist on high-resolution NMR in liquids and solids, this is the first book to address multidimensional solid-state NMR. Multidimensional techniques enable researchers to obtain detailed information about the structure, dynamics, orientation, and phase separation of solids, which provides the basis of a better understanding of materials properties on the molecular level.Dramatic progress-much of it pioneered by the authors-has been achieved in this area, especially in synthetic polymers. Solid-state NMR now favorably competes with well-established techniques, such as light, x-ray, or neutron scattering, electron microscopy, and dielectric and mechanical relaxation. The application of multidimensional solid-state NMR inevitably involves use of concepts from different fields of science. This book also provides the first comprehensive treatment of both the new experimental techniques and the theoretical concepts needed in more complex data analysis. The text addresses spectroscopists and polymer scientists by treating the subject on different levels; descriptive, technical, and mathematical approaches are used when appropriate. It presents an overview of new developments with numerous experimental examples and illustrations, which will appeal to readers interested in both the information content as well as the potential of solid-state NMR. The book also contains many previously unpublished details that will be appreciated by those who want to perform the experiments. The techniques described are applicable not only to the study of synthetic polymers but to numerous problems in solid-state physics, chemistry, materials science, and biophysics. Key Features * Presents original theories and new perspectives on scattering techniques * Provides a systematic treatment of the whole subject * Gives readers access to previously unpublished material * Includes extensive illustrations