Nitric Oxide

Nitric Oxide
Author: Louis J. Ignarro
Publsiher: Academic Press
Total Pages: 1017
Release: 2000-09-13
ISBN 10: 9780080525037
ISBN 13: 0080525032
Language: EN, FR, DE, ES & NL

Nitric Oxide Book Review:

Nitric oxide (NO) is a gas that transmits signals in an organism. Signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. NO is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. NO also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. NO is present in most living creatures and made by many different types of cells. NO research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. Scientists are currently testing whether NO can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. This book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. Edited by Nobel Laureate Louis J. Ignarro, editor of the Academic Press journal, Nitric Oxide Authored by world experts on nitric oxide Includes an overview of basic principles of biology and chemical biology Covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense

Nitric Oxide Protocols

Nitric Oxide Protocols
Author: Aviv Hassid
Publsiher: Springer Science & Business Media
Total Pages: 246
Release: 2004
ISBN 10: 1592598072
ISBN 13: 9781592598076
Language: EN, FR, DE, ES & NL

Nitric Oxide Protocols Book Review:

Carrying on the high standards of the much-praised first edition of Nitric Oxide Protocols, Aviv Hassid has brought together a panel of expert researchers and clinician scientists to describe in step-by-step detail the latest methodologies for the measurement of nitric oxide--and the enzyme that produces it-in biological tissues and fluids. The authors take advantage of the latest methodologies for the quantitation of biological fluids and tissues, including capillary electrophoresis, microcoaxial electrodes, in vivo measurement of nitric oxide in exhaled air, confocal microscopy, gas chromatography, in situ hybridization, and real-time polymerase chain reaction. Chapters on the measurement of the novel products of nitric oxide, such as nitrated proteins, S-nitrosylated proteins, and dioxygen-dependent NO metabolism, are also included. Additional chapters address the expression of nitric oxide synthase via the use of viral vectors in gene therapy for erectile dysfunction and cancer, as well as in retrovirus, adenovirus, or adenoassociated virus-mediated expression of nitric oxide synthase in vivo. The protocols follow the successful Methods in Molecular BiologyTM series format, each one offering step-by-step laboratory instructions, an introduction outlining the principle behind the technique, lists of equipment and reagents, and tips on troubleshooting and avoiding known pitfalls. State-of-the-art and highly practical, Nitric Oxide Protocols, 2nd ed., offers investigators and clinican/scientists a gold-standard collection of readily reproducible analytical techniques for measuring levels of nitric oxide and determining its manifold functions and effects.

Nitric Oxide

Nitric Oxide
Author: Anonim
Publsiher: Academic Press
Total Pages: 454
Release: 2014-08-12
ISBN 10: 0128004398
ISBN 13: 9780128004395
Language: EN, FR, DE, ES & NL

Nitric Oxide Book Review:

First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. The Series provides up-to-date information on vitamin and hormone research spanning data from molecular biology to the clinic. A volume can focus on a single molecule or on a disease that is related to vitamins or hormones. A hormone is interpreted broadly so that related substances, such as transmitters, cytokines, growth factors and others can be reviewed. This volume focuses on nitric oxide. Expertise of the contributors Coverage of a vast array of subjects In depth current information at the molecular to the clinical levels Three-dimensional structures in color Elaborate signaling pathways

The Nitric Oxide No Solution

The Nitric Oxide  No  Solution
Author: Nathan Bryan,Janet Zand,Bill Gottlieb
Publsiher: Unknown
Total Pages: 170
Release: 2010-11
ISBN 10: 9780615417134
ISBN 13: 0615417132
Language: EN, FR, DE, ES & NL

The Nitric Oxide No Solution Book Review:

Eighty-one million Americans have cardiovascular disease, the arterial damage that leads to the heart attacks and strokes that account for 36 percent of all deaths in the U.S. But few people know that boosting the body's levels of a single molecule of nitric oxide can help prevent, control, and even reverse cardiovascular disease.

NO More Heart Disease

NO More Heart Disease
Author: Louis Ignarro
Publsiher: St. Martin's Press
Total Pages: 272
Release: 2006-01-24
ISBN 10: 9781429972451
ISBN 13: 1429972459
Language: EN, FR, DE, ES & NL

NO More Heart Disease Book Review:

Dr. Louis Ignarro discovered "the atom" of cardiovascular health--a tiny molecule called Nitric Oxide. NO, as it is known by chemists, is a signaling molecule produced by the body, and is a vasodilator that helps control blood flow to every part of the body. Dr. Ignarro's findings led to the development of Viagra. Nitric Oxide has a beneficial effect on the cardiovascular system as well. NO relaxes and enlarges the blood vessels, prevents blood clots that trigger strokes and heart attacks, and regulates blood pressure and the accumulation of plaque in the blood vessels. Dr. Ignarro's current research indicates that Nitric Oxide may help lower cholesterol by facilitating the actions of statin drugs like Lipitor. The goal of the regimen presented in NO More Heart Disease is to age proof the cardiovascular system, keeping the vascular network clean and elastic through enhanced NO productivity. The plan is easy-to-follow without extreme lifestyle adjustments, involving taking supplements to stimulate Nitric Oxide production, incorporating NO friendly food into the diet, and a moderate exercise program.

Food Nutrition and the Nitric Oxide Pathway

Food  Nutrition  and the Nitric Oxide Pathway
Author: Nathan S. Bryan
Publsiher: DEStech Publications, Inc
Total Pages: 218
Release: 2010
ISBN 10: 1932078843
ISBN 13: 9781932078848
Language: EN, FR, DE, ES & NL

Food Nutrition and the Nitric Oxide Pathway Book Review:

This book provides a scientific analysis of the effects of foods and nutrients on the NO pathway in humans. Contributors to the book clarify novel chemical and biochemical connections between dietary intake and nitric oxide, particularly in cases of NO deficiency. In this context, the book addresses how specific foods can restore nitric oxide production and bioactivity—without medical interventions. A variety of evidential data is presented showing how NO-rich dietary elements are implicated in disease prevention and modulation. The book offers new knowledge for food technologists, food manufacturers, nutrition researchers, and healthcare practitioners. From the Foreword by Louis J. Ignarro, Nobel Laureate in Physiology/Medicine "The body of work contained in this volume, linking NO to food and nutrition, may have revolutionary implications in terms of developing strategies to combat heart disease and many other contemporary diseases associated with NO deficiency. Proving that a natural and inexpensive regimen of foods rich in nitric oxide activity does restore NO homeostasis can have profound effects on human health…The research presented in this text provides an important expansion of NO work…(and) Dr. Nathan Bryan, the editor…is to be congratulated for…communicating new knowledge and assembling the world's experts in their fields."

Functional Neuroanatomy of the Nitric Oxide System

Functional Neuroanatomy of the Nitric Oxide System
Author: H.W.M. Steinbusch,J. de Vente,S.R. Vincent
Publsiher: Elsevier
Total Pages: 472
Release: 2000-06-30
ISBN 10: 9780080532080
ISBN 13: 008053208X
Language: EN, FR, DE, ES & NL

Functional Neuroanatomy of the Nitric Oxide System Book Review:

This volume of the Handbook of Neuroanatomy is concerned with nitric oxide synthase. In this volume different research areas are presented together, which adds up to the first major review volume on the localization of nitric oxide synthase in the nervous system. The subjects range from developmental aspects in vertebrates to a functional neuroanatomy of the nervous system in vertebrates. This presentation gives an impressive look on the overwhelming presence of NOS in animal organism and the significance of NO - cGMP signaling. By clearly stating the limitations of our present knowledge the book is also a stimulant for further research. This book presents for the first time an overview of NOS and NO-cGMP signaling in the retina and urogenital system. In addition the effects if injuries on the expression of NOS are summarized in a number of models, which has not been done before. The frame of the book is a classical neuroanatomic description of the localization of NOS. Several authors give detailed advice to prevent pitfalls which may occur when different methods to locate NOS are used. In addition, several chapters detail the target structures for NO while describing the localization of NOS at the same time. All these points together make this volume very timely, i.e. overviewing a decade of NO research.

Nitric Oxide Donors

Nitric Oxide Donors
Author: Amedea Seabra
Publsiher: Academic Press
Total Pages: 364
Release: 2017-03-17
ISBN 10: 0128134593
ISBN 13: 9780128134597
Language: EN, FR, DE, ES & NL

Nitric Oxide Donors Book Review:

Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions. Provides background information about biology and chemistry of nitric oxide Discusses the state-of-the-art in the design of nitric oxide releasing nanomaterials for biomedical applications Covers the usage of nitric oxide donors in the treatment of several conditions, such as cancer, human skin, cardiovascular system, and immunity Discusses the future of nitric oxide donors and their FDA approval

Nitric Oxide

Nitric Oxide
Author: Jack Lancaster, Jr.
Publsiher: Elsevier
Total Pages: 355
Release: 1996-07-27
ISBN 10: 0080537545
ISBN 13: 9780080537542
Language: EN, FR, DE, ES & NL

Nitric Oxide Book Review:

This unique sourcebook serves as a comprehensive reference, bridging the well-established chemistry of nitric oxide and the new and exciting role of nitric oxide as an effector and signaling molecule in numerous biological systems. Nitric Oxide: Principles and Actions relates the chemical properties of the molecule to its possible effects on biological systems, under both normal physiological and pathophysiological conditions. Combining the chemistry and analysis of nitric oxide with newer studies of the relevance of the molecule gives this book a long life, making it extremely useful to researchers in a number of areas. Provides a much needed compilation of what is known about nitric oxide and its properties Enables researchers to understand the importance and use of nitric oxide in systems of study Covers an area of tremendous growth in research Provides the first collection of the roles of nitric oxide in microbial and mammalian systems and as a probe of metalloenzymes Presents the historically important role of nitric oxide in food preservation

Nitric Oxide

Nitric Oxide
Author: Louis J. Ignarro,Bruce Freeman
Publsiher: Academic Press
Total Pages: 434
Release: 2017-08-03
ISBN 10: 0128043199
ISBN 13: 9780128043196
Language: EN, FR, DE, ES & NL

Nitric Oxide Book Review:

Nitric Oxide: Biology and Pathobiology, Third Edition, provides information on nitric oxide, a signaling molecule of key importance for the cardiovascular system that regulates blood pressure and blood flow to different organs. With recent links to the role of nitric oxide in the expression of healthy benefits of controlled diet and aerobic exercise, and the reactions of nitric oxide that can impact cell signaling, this book provides a comprehensive resource during a time when increased research attention is being paid across the fields of biochemistry, chemistry, molecular biology, gene therapy, cell biology, immunology, pharmacology, neuroscience, and physiology. Includes perspectives from Jack Lancaster on the discovery of EDRF and nitric oxide Provides detailed coverage of the new gaseous signaling agents Features expanded coverage on the principles of biology, including nitric oxide synthases, nitrite and nitrate biology and pathobiology, and signaling mechanisms Incorporates expanded pathobiology coverage, including nitric oxide and cardiovascular function, obesity, diabetes, and erectile function/dysfunction

Nitric Oxide and the Cardiovascular System

Nitric Oxide and the Cardiovascular System
Author: Joseph Loscalzo,Joseph A. Vita
Publsiher: Springer Science & Business Media
Total Pages: 601
Release: 2000-03-29
ISBN 10: 1592590020
ISBN 13: 9781592590025
Language: EN, FR, DE, ES & NL

Nitric Oxide and the Cardiovascular System Book Review:

Leading clinical and experimental investigators comprehensively review the chemistry, biochemistry, molecular biology, physiology, and pathophysiology of nitric oxide in the cardiovascular systems. These experts particularly illuminate nitric oxide biology, its cardiovascular pathophysiology, and its role in cardiovascular therapeutics. Topics also included are the development of nitric oxide donors for the treatment of myocardial ischemia and thrombosis, the development of gene therapeutic restoration of endothelial function in atherosclerosis, and the application of nitric oxide biology to investigative arenas in cardiovascular medicine. With its balanced presentation of basic and clinically relevant information, Nitric Oxide and the Cardiovascular System provides a comprehensive, authoritative guide for all those cardiovascular biologists, cardiologists, physiologists, and cardiovascular surgeons engaged in today's clinical or experimental research.

Nitric Oxide and the Regulation of the Peripheral Circulation

Nitric Oxide and the Regulation of the Peripheral Circulation
Author: Philip J. Kadowitz,Dennis B. McNamara
Publsiher: Springer Science & Business Media
Total Pages: 362
Release: 2000
ISBN 10: 9780817640460
ISBN 13: 0817640460
Language: EN, FR, DE, ES & NL

Nitric Oxide and the Regulation of the Peripheral Circulation Book Review:

Nitric oxide is involved in the regulation of the circulation in physiologic and pathophysiological conditions. Evidence indicates that alterations in endothelial production of nitric oxide may be involved in the pathogenesis of central hypertension, pulmonary hypertension, renal disease and coronary vasopastic disorders. In addition to being involved in regulation of the circulation in physiologic and pathophysiologic conditions, the inducible form of the enzyme may play a role in the refractory hypertension.

Role of Nitric Oxide in Sepsis and ARDS

Role of Nitric Oxide in Sepsis and ARDS
Author: M.P. Fink,D. Payen
Publsiher: Springer Science & Business Media
Total Pages: 430
Release: 2012-12-06
ISBN 10: 3642799205
ISBN 13: 9783642799204
Language: EN, FR, DE, ES & NL

Role of Nitric Oxide in Sepsis and ARDS Book Review:

Nitric Oxide (NO) is a free radical, a gas, and a pluripotent product of mammalian cells. Only a few years ago, scientific discussions of NO were largely held in the context of the chemistry of air pollution. Now, however, the great significance of NO as a signalling and cytotoxic molecule has captured the attention of the biomedical community. This book provides a very up-to-date review of the role of NO in sepsis and ARDS. Consideration is given to NO both as a pathophysiologic mediator as well as a therapeutic agent. An internationally recognized group of scientists and clinicians have contributed chapters dealing with cutting-edge science and practical clinical strategies. Numerous tables and charts have been included to aid the reader in understanding this fascinating and important subject.

Artemisinin and Nitric Oxide

Artemisinin and Nitric Oxide
Author: Qing-Ping Zeng
Publsiher: Springer
Total Pages: 126
Release: 2015-07-08
ISBN 10: 9783662476871
ISBN 13: 3662476878
Language: EN, FR, DE, ES & NL

Artemisinin and Nitric Oxide Book Review:

This book discusses both the beneficial and harmful aspects of NO in biology and medicine, and also introduces the emerging discovery of artemisinin in antitumor, antibacterial infection, anti-inflammation, and antiaging contexts. In 1992 nitric oxide (NO) was voted “Molecule of the Year” by Science magazine, and the discovery of its physiological roles has led to Nobel Prize-winning work in neuroscience, physiology and immunology. The book explains why we should maintain a steady-state NO level that is derived from neuronal or epithelial NO synthase, and avoid the extremely high NO level resulting from inducible NO synthase. The book offers a valuable resource for medical chemists, clinicians, biologists and all those interested in health and disease.

The Pritikin Edge

The Pritikin Edge
Author: Robert A. Vogel,Paul Tager Lehr
Publsiher: Simon and Schuster
Total Pages: 400
Release: 2008-09-23
ISBN 10: 1416583637
ISBN 13: 9781416583639
Language: EN, FR, DE, ES & NL

The Pritikin Edge Book Review:

We Americans may reside in the greatest nation on earth, but our lifestyle is killing us. Onequarter of us still smoke, two-thirds of us are fat, three-quarters of us don't exercise, and stress and depression are ubiquitous. We wolf down oversize portions of fast food in minutes and boast of not having taken a vacation in years. We get misinformation like "olive oil is healthy" but then get fatter because drizzling three tablespoons of oil on a salad adds as many calories as two scoops of premium ice cream. Despite all our advances in drugs and surgery, obesity and the diseases it causes have shortened life expectancy; this is the first time in history that children can expect to die younger than their parents. The Pritikin Program was the first comprehensive lifestyle program in America, and after fifty years on the cutting edge of lifestyle science, it is still the longest-running, most successful program for reversing many of modern society's diseases, including obesity, heart disease, and diabetes. What sets Pritikin apart from the myriad of other diets is that its program is based on real science. Pritikin doesn't make random claims or base advice on half-truths or fads; Pritikin's effectiveness has been proven and documented in more than 110 scientific studies. You've picked up this book because you want to change your lifestyle, improve your health, and live longer, and with the program in these pages, you can start reversing the effects of years of unhealthy living today. Here you'll find the ten simple lifestyle ingredients that will change your life. Stick with them and you'll lose weight without feeling hungry, your energy will surge, and you will look and feel healthier and stronger than you have in years. Included are more than 75 recipes for flavorful and healthful dishes, detailed meal plans, and tips for dining out healthfully and happily. You'll learn what kinds of physical activities are most effective and how to make the most of your time on the road or in the gym. You'll get sets of simple exercises you can do anywhere that will make you strong, help you shed fat, and keep you toned. The real science of lifestyle and heart health, from fat molecules to heart attacks, is described in accessible terms, and popular diet myths are debunked. You'll find out why lowcarbohydrate or other fad diets won't help you lose weight in the long run and why they won't improve your overall health. The Pritikin Edge gives you the real facts so you can take control of your health and add years to your life and quality to your years. Once you begin living with these principles, you'll wonder how you ever lived any other way.

Nitric Oxide Synthase

Nitric Oxide Synthase
Author: Seyed Soheil Saeedi Saravi
Publsiher: BoD – Books on Demand
Total Pages: 248
Release: 2017-05-17
ISBN 10: 953513163X
ISBN 13: 9789535131632
Language: EN, FR, DE, ES & NL

Nitric Oxide Synthase Book Review:

Nitric Oxide Synthase - Simple Enzyme-Complex Roles provides information on nitric oxide synthase, a biomolecule of key importance for the different biological systems, including central and peripheral nervous, cardiovascular, and reproductive systems. With recent links to the role of nitric oxide in the reactions that can impact cell signaling, and discoveries surrounding the complex role of nitric oxide synthase that have increased research attention across the fields of cell and molecular biology, physiology, pharmacology, toxicology, neuroscience, cardiology, urology, and endocrinology, this book tries to provide a comprehensive overview of biology/pathobiology of nitric oxide synthases and a perspective from possible therapeutic indication of the enzyme inhibitors.

WHO Guidelines for Indoor Air Quality

WHO Guidelines for Indoor Air Quality
Author: World Health Organization
Publsiher: World Health Organization
Total Pages: 454
Release: 2010
ISBN 10: 1928374650XXX
ISBN 13: UCBK:C105261333
Language: EN, FR, DE, ES & NL

WHO Guidelines for Indoor Air Quality Book Review:

This book presents WHO guidelines for the protection of public health from risks due to a number of chemicals commonly present in indoor air. The substances considered in this review, i.e. benzene, carbon monoxide, formaldehyde, naphthalene, nitrogen dioxide, polycyclic aromatic hydrocarbons (especially benzo[a]pyrene), radon, trichloroethylene and tetrachloroethylene, have indoor sources, are known in respect of their hazardousness to health and are often found indoors in concentrations of health concern. The guidelines are targeted at public health professionals involved in preventing health risks of environmental exposures, as well as specialists and authorities involved in the design and use of buildings, indoor materials and products. They provide a scientific basis for legally enforceable standards.

Methods in Nitric Oxide Research

Methods in Nitric Oxide Research
Author: Martin Feelisch,Jonathan Stamler
Publsiher: John Wiley & Sons Incorporated
Total Pages: 712
Release: 1996-06-04
ISBN 10: 1928374650XXX
ISBN 13: UCSD:31822023942634
Language: EN, FR, DE, ES & NL

Methods in Nitric Oxide Research Book Review:

This handbook describes methods for the measurement and investigation of nitric oxide. The topics discussed include the metabolism of substrates and cofactors, the detection of nitrogen oxides, the detection of nitrogen oxide synthase activity, and the detection of adducts and reaction products.

Nitric Oxide in Brain Development Plasticity and Disease

Nitric Oxide in Brain Development  Plasticity  and Disease
Author: R. Ranney Mize
Publsiher: Elsevier Science Limited
Total Pages: 302
Release: 1998
ISBN 10: 9780444828859
ISBN 13: 0444828850
Language: EN, FR, DE, ES & NL

Nitric Oxide in Brain Development Plasticity and Disease Book Review:

Nitric oxide, "Molecule of the Year" in 1995, continues to be one of the most widely studied molecules in brain research. This excellent volume elucidates the implications of this gas in a variety of brain processes. The volume is divided into five sections, describing: the mechanisms underlying the release and action of Nitric Oxide in the CNS, and the distribution of Nitric Oxide in the brain using various techniques; how Nitric Oxide interacts with and regulates the N-methyl-D-aspartate receptor; the role of Nitric Oxide in pathway refinement and synapse stabilization in the developing CNS; the role of Nitric Oxide in adult brain plasticity including long-term potentiation and depression; and the role of Nitric Oxide in brain injury such as occurs during ischemia and other events produced by glutamate neurotoxicity, and in neuroprotective mechanisms that promote neuron survival. Nitric Oxide in Brain Development, Plasticity, and Disease is the first Progress in Brain Research volume to be published in abstracted form on the World Wide Web. It includes title pages, abstracts, selected figures, and complete references. It also includes a digital brain atlas for readers to view a mouse brain in a three-dimensional full-color rendition, and much more.

Nitrosation Reactions and the Chemistry of Nitric Oxide

Nitrosation Reactions and the Chemistry of Nitric Oxide
Author: D.L.H. Williams
Publsiher: Elsevier
Total Pages: 280
Release: 2004-12-16
ISBN 10: 9780080473604
ISBN 13: 0080473601
Language: EN, FR, DE, ES & NL

Nitrosation Reactions and the Chemistry of Nitric Oxide Book Review:

Since 1988, there has been much literature published on the chemistry of nitric oxide, particularly in the field of S-nitrosation and the chemistry of S-nitroso compounds. Written by a chemist for the chemistry community, this book provides an update of the chemistry of nitrosation reactions, dealing with both the synthetic and mechanistic aspects of these reactions. It also looks at the chemistry of nitric oxide in relation to the amazing biological properties of this simple diatomic molecule, which were unknown until around 1990. * Provides an update on previously published literature on nitric oxide chemistry * Contains chapters on reagents for nitrosation, nitrosation at nitrogen, aliphatic and aromatic carbon, oxygen, sulfur and metal centres * Looks at hot research topics such as synthesis, properties and reactions of s-nitrosothiols