New Targeting in The Reversal of Resistant Glioblastomas

New Targeting in The Reversal of Resistant Glioblastomas
Author: Ali Syed Arbab
Publsiher: Academic Press
Total Pages: 202
Release: 2021-03-01
ISBN 10: 0128232765
ISBN 13: 9780128232767
Language: EN, FR, DE, ES & NL

New Targeting in The Reversal of Resistant Glioblastomas Book Review:

New Targeting in The Reversal of Resistant Glioblastomas discusses alternative treatment strategies that not only target tumor cells but also target the tumor microenvironment, metabolic pathways and interaction of cytokines in tumor cells. The current treatment for primary and recurrent glioblastomas is failing because clinicians are not considering the effect of bone marrow derived cells to the development of resistance to clinically practiced therapies. This book helps readers rethink treatment strategies to successfully fight glioblastomas. It is a valuable resource for cancer researchers, clinicians, graduate students and other members of the biomedical field. Explains the effect of bone marrow derived cells on the development of resistance to clinically practiced therapies Provides information on the availability of alternate therapies for recurrent glioblastoma when standard practices have failed Discusses targeting tumor microenvironment using available FDA approved drugs as an alternative treatment strategy for glioblastoma

Glioblastoma Resistance to Chemotherapy Molecular Mechanisms and Innovative Reversal Strategies

Glioblastoma Resistance to Chemotherapy  Molecular Mechanisms and Innovative Reversal Strategies
Author: Tarik F. Massoud,Ramasamy Paulmurugan
Publsiher: Academic Press
Total Pages: 350
Release: 2021-03-15
ISBN 10: 9780128215678
ISBN 13: 0128215674
Language: EN, FR, DE, ES & NL

Glioblastoma Resistance to Chemotherapy Molecular Mechanisms and Innovative Reversal Strategies Book Review:

Glioblastoma Resistance to Chemotherapy: Molecular Mechanisms and Innovative Reversal Strategies brings current knowledge from an international team of experts on the science and clinical management of glioblastoma chemoresistance. The book discusses topics such as molecular mechanisms of chemoresistance, experimental models to study chemoresistance, chemoresistance to drugs other than Temozolomide, and specific strategies to reverse chemoresistance. Additionally, it encompasses information on how to mitigate chemoresistance by targeted enhancement of p53 function. This book is a valuable resource for cancer researchers, oncologists, neuro-oncologists and other members of the biomedical field. Glioblastoma (GBM) is the most invasive and malignant primary brain tumor in humans with poor survival after diagnosis, therefore it is imperative that molecular and cellular mechanisms behind therapy resistant GBM cells, as well as the therapeutic strategies available to counter the resistance are comprehensively understood. Provides comprehensive, core knowledge related to the entire discipline of glioblastoma chemoresistance, from its many etiological mechanisms, to specific strategies to reverse resistance Presents current information from an international team of experts on the basic science, pre-clinical research, and clinical management of glioblastoma chemoresistance Discusses molecular and cellular mechanisms behind therapy resistant glioblastoma cells, as well as the therapeutic strategies available to counter this resistance

Journal of the National Cancer Institute

Journal of the National Cancer Institute
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1991
ISBN 10:
ISBN 13: MINN:30000002414385
Language: EN, FR, DE, ES & NL

Journal of the National Cancer Institute Book Review:

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1995
ISBN 10:
ISBN 13: UIUC:30112005408932
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Review:

Index Medicus

Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2004
ISBN 10:
ISBN 13: OSU:32436011091889
Language: EN, FR, DE, ES & NL

Index Medicus Book Review:

Biomedical Index to PHS supported Research

Biomedical Index to PHS supported Research
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1992
ISBN 10:
ISBN 13: MINN:31951P00216726J
Language: EN, FR, DE, ES & NL

Biomedical Index to PHS supported Research Book Review:

Anticancer Research

Anticancer Research
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1990
ISBN 10:
ISBN 13: NWU:35558002651509
Language: EN, FR, DE, ES & NL

Anticancer Research Book Review:

Pharmacotherapy

Pharmacotherapy
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1996
ISBN 10:
ISBN 13: UCLA:L0075680066
Language: EN, FR, DE, ES & NL

Pharmacotherapy Book Review:

Cancer Research

Cancer Research
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2008
ISBN 10:
ISBN 13: NWU:35558005676859
Language: EN, FR, DE, ES & NL

Cancer Research Book Review:

Breast Cancer Management

Breast Cancer Management
Author: Lynda R. Wiseman
Publsiher: Lippincott Williams & Wilkins
Total Pages: 133
Release: 2000
ISBN 10:
ISBN 13: UCSD:31822028487379
Language: EN, FR, DE, ES & NL

Breast Cancer Management Book Review:

Journal of the National Cancer Institute

Journal of the National Cancer Institute
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1996
ISBN 10:
ISBN 13: NWU:35558004792541
Language: EN, FR, DE, ES & NL

Journal of the National Cancer Institute Book Review:

"Summaries of papers" contained in the journal accompany each issue, 19--

An Innovative Approach to Understanding and Treating Cancer Targeting pH

An Innovative Approach to Understanding and Treating Cancer  Targeting pH
Author: Tomas Koltai,Stephan J. Reshkin,Salvador Harguindey
Publsiher: Academic Press
Total Pages: 574
Release: 2020-01-16
ISBN 10: 0128190604
ISBN 13: 9780128190609
Language: EN, FR, DE, ES & NL

An Innovative Approach to Understanding and Treating Cancer Targeting pH Book Review:

An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve either a stable disease or even regression with no toxicity. The book discusses topics such as lactic acid and its transport system in the pH paradigm, mechanisms to decrease extra cellular pH and increase intracellular pH, NHE-1 activity in cancer, carbonic anhydrases, vacuolar ATPase proton pump, and the sodium-bicarbonate cotransporter system. Additionally, it discusses complementary pharmacological interventions, cellular acidification and extracellular alkalinization as a new and integral approach to cancer treatment. Analyzes the mechanisms that lead to the inversion of pH gradient in cancer tissues Summarizes almost 100 years of research on pH inversion in cancer in one single source, discussing the most relevant and updated researches in the field Proposes new efficient treatments against cancer using pH inversion mechanisms, either with new drugs like proton transport inhibitors and proton pump inhibitors (PTIs and PPIs) or with repurposed drugs

Cancer Drug Resistance

Cancer Drug Resistance
Author: Beverly A. Teicher
Publsiher: Springer Science & Business Media
Total Pages: 617
Release: 2007-11-09
ISBN 10: 1597450359
ISBN 13: 9781597450355
Language: EN, FR, DE, ES & NL

Cancer Drug Resistance Book Review:

Leading experts summarize and synthesize the latest discoveries concerning the changes that occur in tumor cells as they develop resistance to anticancer drugs, and suggest new approaches to preventing and overcoming it. The authors review physiological resistance based upon tumor architecture, cellular resistance based on drug transport, epigenetic changes that neutralize or bypass drug cytotoxicity, and genetic changes that alter drug target molecules by decreasing or eliminating drug binding and efficacy. Highlights include new insights into resistance to antiangiogenic therapies, oncogenes and tumor suppressor genes in therapeutic resistance, cancer stem cells, and the development of more effective therapies. There are also new findings on tumor immune escape mechanisms, gene amplification in drug resistance, the molecular determinants of multidrug resistance, and resistance to taxanes and Herceptin.

Glucocorticoids and Mood

Glucocorticoids and Mood
Author: Lewis L. Judd,Esther M. Sternberg
Publsiher: Wiley-Blackwell
Total Pages: 352
Release: 2009-11-23
ISBN 10:
ISBN 13: STANFORD:36105213128080
Language: EN, FR, DE, ES & NL

Glucocorticoids and Mood Book Review:

"This volume presents papers stemming from the conference "Glucocorticoids and Mood: Clinical Manifestations, Risk Factors and Molecular Mechanisms" held on July 20-21, 2008 in San Diego, California"--P. v.

Central Nervous System Tumours

Central Nervous System Tumours
Author: Thomas J. Deeley
Publsiher: Unknown
Total Pages: 323
Release: 1974
ISBN 10:
ISBN 13: UOM:39015000297740
Language: EN, FR, DE, ES & NL

Central Nervous System Tumours Book Review:

Neurooncology

Neurooncology
Author: Amit Agrawal
Publsiher: BoD – Books on Demand
Total Pages: 488
Release: 2016-07-13
ISBN 10: 9535124250
ISBN 13: 9789535124252
Language: EN, FR, DE, ES & NL

Neurooncology Book Review:

The book contains the information of various aspects of newer developments and recent advances in the field of central nervous system (CNS) tumor molecular biology, tumor progression, clinical presentation, imaging and management. The authors from different reputed institutions shared their knowledge on this open access platform to disseminate their knowledge at global level. As it is obvious in the current text, the field of neurooncology is heterogeneous and under continuous development with addition of new knowledge and information on regular basis. The collective contributions from experts attempt to provide updates regarding ongoing research and developments pertaining to CNS tumor genetics and molecular aspects and their applied aspect in reference to patient management.

The Journal of Neuroscience

The Journal of Neuroscience
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2009
ISBN 10:
ISBN 13: NWU:35558005745258
Language: EN, FR, DE, ES & NL

The Journal of Neuroscience Book Review:

Oncology of Infancy and Childhood E Book

Oncology of Infancy and Childhood E Book
Author: Stuart H. Orkin,David E. Fisher,A. Thomas Look,Samuel Lux,David Ginsburg,David G. Nathan
Publsiher: Elsevier Health Sciences
Total Pages: 1392
Release: 2009-06-09
ISBN 10: 1437721389
ISBN 13: 9781437721386
Language: EN, FR, DE, ES & NL

Oncology of Infancy and Childhood E Book Book Review:

To address the growing complexities of childhood cancer, Nathan and Oski’s Hematology and Oncology of Infancy and Childhood has now been separated into two distinct volumes. With this volume devoted strictly to pediatric oncology, and another to pediatric hematology, you will be on the cutting edge of these two fields. This exciting new, full-color reference provides you with the most comprehensive, authoritative, up-to-date information for diagnosing and treating children with cancer. It brings together the pathophysiology of disease with detailed clinical guidance on diagnosis and management for the full range of childhood cancers, including aspects important in optimal supportive care. Written by the leading names in pediatric oncology, this resource is an essential tool for all who care for pediatric cancer patients. Offers comprehensive coverage of all pediatric cancers, including less common tumors, making this the most complete guide to pediatric cancer. Covers emerging research developments in cancer biology and therapeutics, both globally and in specific pediatric tumors. Includes a section on supportive care in pediatric oncology, written by authors who represent the critical subdisciplines involved in this important aspect of pediatric oncology. Uses many boxes, graphs, and tables to highlight complex clinical diagnostic and management guidelines. Presents a full-color design that includes clear illustrative examples of the relevant pathology and clinical issues, for quick access to the answers you need. Incorporates the codified WHO classification for all lymphomas and leukemias.

New Research Directions in DNA Repair

New Research Directions in DNA Repair
Author: Clark Chen
Publsiher: BoD – Books on Demand
Total Pages: 674
Release: 2013-05-22
ISBN 10: 9535111140
ISBN 13: 9789535111146
Language: EN, FR, DE, ES & NL

New Research Directions in DNA Repair Book Review:

This book is intended for students and scientists working in the field of DNA repair. Select topics are presented here to illustrate novel concepts in DNA repair, the cross-talks between DNA repair and other fundamental cellular processes, and clinical translational efforts based on paradigms established in DNA repair. The book should serve as a supplementary text in courses and seminars as well as a general reference for biologists with an interest in DNA repair.

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor
Author: Terry Lichtor
Publsiher: BoD – Books on Demand
Total Pages: 434
Release: 2015-03-25
ISBN 10: 953512031X
ISBN 13: 9789535120315
Language: EN, FR, DE, ES & NL

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor Book Review:

A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.