Neurotherapeutics in the Era of Translational Medicine

Neurotherapeutics in the Era of Translational Medicine
Author: Richard A. Smith,Brian K. Kaspar,Clive N. Svendsen
Publsiher: Academic Press
Total Pages: 518
Release: 2020-11-28
ISBN 10: 0128172746
ISBN 13: 9780128172742
Language: EN, FR, DE, ES & NL

Neurotherapeutics in the Era of Translational Medicine Book Review:

For the first time in history, there is now hope for treating neurological disorders that had previously been considered untreatable. The remarkable confluence of events that has heralded this is the focus of Neurotherapeutics in the Era of Translational Medicine. This anthology, written by many of the prominent scientists and researchers in the field of biotechnology, recounts the breathtaking advances that are revolutionizing treatment for disorders such as amyotrophic lateral sclerosis‎, spinal muscular atrophy, multiple sclerosis, Parkinson’s disease, myasthenia gravis, migraine, and glioblastoma. The "story behind the story" of these translational efforts is told, with authors depicting the ups and downs encountered on the path of their drug discovery and development effort. In parallel with this path, advances in identifying novel biomarkers and disease models are summarized, as are contemporary issues focusing on clinical trial design, bioethics, innovative funding strategies, and collaborations between government and academia in an effort to facilitate breakthrough treatments. The book is written by members of the biotech and pharmaceutical ecosystem for those who belong to it and aspire to become part of it. Comprehensive review on the progress of translational research in neurotherapeutics for neurologic disorders Discusses important issues in clinical trials such as design and ethical issues Written for neuroscientists, neurologists and pharmacologists

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2007

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 2007
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publsiher: Unknown
Total Pages: 329
Release: 2006
ISBN 10:
ISBN 13: MINN:31951D025981127
Language: EN, FR, DE, ES & NL

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2007 Book Review:

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2007 Testimony of members of Congress and other interested individuals and organizations

Departments of Labor  Health and Human Services  Education  and Related Agencies Appropriations for 2007  Testimony of members of Congress and other interested individuals and organizations
Author: United States. Congress. House. Committee on Appropriations. Subcommittee on the Departments of Labor, Health and Human Services, Education, and Related Agencies
Publsiher: Unknown
Total Pages: 329
Release: 2006
ISBN 10:
ISBN 13: UCBK:C086420147
Language: EN, FR, DE, ES & NL

Departments of Labor Health and Human Services Education and Related Agencies Appropriations for 2007 Testimony of members of Congress and other interested individuals and organizations Book Review:

Neurological Emergencies

Neurological Emergencies
Author: Alejandro A. Rabinstein
Publsiher: Springer Nature
Total Pages: 390
Release: 2019-11-28
ISBN 10: 3030280721
ISBN 13: 9783030280727
Language: EN, FR, DE, ES & NL

Neurological Emergencies Book Review:

This comprehensive and up-to-date book covers the common emergencies in neurology, neurosurgery, and psychiatry. Chapters examine a variety of neurological emergencies, and offer pragmatic approaches to treatment and management. High-quality tables, figures, and algorithms supplement expertly written text, and provide readers with clear, rapid answers in an easily accessible format. Additionally, the book includes discussions on less common conditions, and incorporates specific methods for treating specific populations, such as pregnant women and transplant patients. Neurological Emergencies: A Practical Approach is a go-to reference for all medical professions working in emergency treatment settings, and will increase their ability to better care for patients with acute neurological diseases.

Mind Fixers Psychiatry s Troubled Search for the Biology of Mental Illness

Mind Fixers  Psychiatry s Troubled Search for the Biology of Mental Illness
Author: Anne Harrington
Publsiher: W. W. Norton & Company
Total Pages: 384
Release: 2019-04-16
ISBN 10: 1324001976
ISBN 13: 9781324001973
Language: EN, FR, DE, ES & NL

Mind Fixers Psychiatry s Troubled Search for the Biology of Mental Illness Book Review:

Mind Fixers tells the history of psychiatry’s quest to understand the biological basis of mental illness and asks where we need to go from here. In Mind Fixers, Anne Harrington, author of The Cure Within, explores psychiatry’s repeatedly frustrated struggle to understand mental disorder in biomedical terms. She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds. But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time. Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well. In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones. A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.

Surgical Neuro Oncology

Surgical Neuro Oncology
Author: Russell R. Lonser,J. Bradley Elder
Publsiher: Neurosurgery by Example
Total Pages: 312
Release: 2018-11-09
ISBN 10: 0190696699
ISBN 13: 9780190696696
Language: EN, FR, DE, ES & NL

Surgical Neuro Oncology Book Review:

Part of the Neurosurgery by Example series, this volume on surgical neuro-oncology presents exemplary cases in which renowned authors guide readers through the assessment and planning, decision making, surgical procedure, after care, and complication management of common and uncommon disorders. The cases explore a number of different types of nervous systems tumors, including glioblastoma, medulloblastoma, skull tumors, and more. Each chapter also contains 'pivot points' that illuminate changes required to manage patients in alternate or atypical situations, and pearls for accurate diagnosis, successful treatment, and effective complication management. Containing a focused review of medical evidence and expected outcomes, Surgical Neuro-Oncology is appropriate for neurosurgeons who wish to learn more about this subspecialty, and those preparing for the American Board of Neurological Surgery oral examination.

Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Health Sciences Policy,Committee on Pain Management and Regulatory Strategies to Address Prescription Opioid Abuse
Publsiher: National Academies Press
Total Pages: 482
Release: 2017-09-28
ISBN 10: 0309459575
ISBN 13: 9780309459570
Language: EN, FR, DE, ES & NL

Pain Management and the Opioid Epidemic Book Review:

Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.

Encyclopedia of Tissue Engineering and Regenerative Medicine

Encyclopedia of Tissue Engineering and Regenerative Medicine
Author: Anonim
Publsiher: Academic Press
Total Pages: 1418
Release: 2019-06-04
ISBN 10: 0128137002
ISBN 13: 9780128137000
Language: EN, FR, DE, ES & NL

Encyclopedia of Tissue Engineering and Regenerative Medicine Book Review:

Encyclopedia of Tissue Engineering and Regenerative Medicine provides a comprehensive collection of personal overviews on the latest developments and likely future directions in the field. By providing concise expositions on a broad range of topics, this encyclopedia is an excellent resource. Tissue engineering and regenerative medicine are relatively new fields still in their early stages of development, yet they already show great promise. This encyclopedia brings together foundational content and hot topics in both disciplines into a comprehensive resource, allowing deeper interdisciplinary research and conclusions to be drawn from two increasingly connected areas of biomedicine. Provides a ‘one-stop’ resource for access to information written by world-leading scholars in the fields of tissue engineering and regenerative medicine Contains multimedia features, including hyperlinked references and further readings, cross-references and diagrams/images Represents the most comprehensive and exhaustive product on the market on the topic

An Essay on the Shaking Palsy

An Essay on the Shaking Palsy
Author: James Parkinson
Publsiher: Unknown
Total Pages: 66
Release: 1817
ISBN 10:
ISBN 13: NWU:35558004985954
Language: EN, FR, DE, ES & NL

An Essay on the Shaking Palsy Book Review:

Regenerative Pharmacology

Regenerative Pharmacology
Author: George J. Christ,Karl-Erik Andersson
Publsiher: Cambridge University Press
Total Pages: 329
Release: 2013-04-15
ISBN 10: 1107354730
ISBN 13: 9781107354739
Language: EN, FR, DE, ES & NL

Regenerative Pharmacology Book Review:

Regenerative medicine is broadly defined as the repair or replacement of damaged cells, tissues and organs. It is a multidisciplinary effort in which technologies derive from the fields of cell, developmental and molecular biology; chemical and material sciences (i.e. nanotechnology); engineering; surgery; transplantation; immunology; molecular genetics; physiology; and pharmacology. As regenerative medicine technologies continue to evolve and expand across the boundaries of numerous scientific disciplines, they remain at the forefront of the translational research frontier with the potential to radically alter the treatment of a wide variety of disease and dysfunction. This book will draw attention to the critical role that pharmacological sciences will undeniably play in the advancement of these treatments. This book is invaluable for advanced students, postdoctoral fellows, researchers new to the field of regenerative medicine/tissue engineering, and experienced investigators looking for new research avenues. The first state-of-the-art book in this rapidly evolving field of research.

Emerging Cognitive Neuroscience and Related Technologies

Emerging Cognitive Neuroscience and Related Technologies
Author: National Research Council,Division on Behavioral and Social Sciences and Education,Board on Behavioral, Cognitive, and Sensory Sciences,Division on Engineering and Physical Sciences,Standing Committee for Technology Insight--Gauge, Evaluate, and Review,Committee on Military and Intelligence Methodology for Emergent Neurophysiological and Cognitive/Neural Science Research in the Next Two Decades
Publsiher: National Academies Press
Total Pages: 214
Release: 2008-12-06
ISBN 10: 0309118948
ISBN 13: 9780309118941
Language: EN, FR, DE, ES & NL

Emerging Cognitive Neuroscience and Related Technologies Book Review:

Emerging Cognitive Neuroscience and Related Technologies, from the National Research Council, identifies and explores several specific research areas that have implications for U.S. national security, and should therefore be monitored consistently by the intelligence community. These areas include: neurophysiological advances in detecting and measuring indicators of psychological states and intentions of individuals the development of drugs or technologies that can alter human physical or cognitive abilities advances in real-time brain imaging breakthroughs in high-performance computing and neuronal modeling that could allow researchers to develop systems which mimic functions of the human brain, particularly the ability to organize disparate forms of data. As these fields continue to grow, it will be imperative that the intelligence community be able to identify scientific advances relevant to national security when they occur. To do so will require adequate funding, intelligence analysts with advanced training in science and technology, and increased collaboration with the scientific community, particularly academia. A key tool for the intelligence community, this book will also be a useful resource for the health industry, the military, and others with a vested interest in technologies such as brain imaging and cognitive or physical enhancers.

Nervous System Drug Delivery

Nervous System Drug Delivery
Author: Russell R. Lonser,Malisa Sarntinoranont,Kristof Bankiewicz
Publsiher: Academic Press
Total Pages: 556
Release: 2019-06-25
ISBN 10: 0128139986
ISBN 13: 9780128139981
Language: EN, FR, DE, ES & NL

Nervous System Drug Delivery Book Review:

Nervous System Drug Delivery: Principles and Practice helps users understand the nervous system physiology affecting drug delivery, the principles that underlie various drug delivery methods, and the appropriate application of drug delivery methods for drug- and disease-specific treatments. Researchers developing nervous system putative therapeutic agents will use this book to optimize drug delivery during preclinical assessment and to prepare for regulatory advancement of new agents. Clinicians will gain direct insights into pathophysiologic alterations that impact drug delivery and students and trainees will find this a critical resource for understanding and applying nervous system drug delivery techniques. Offers an up-to-date, comprehensive resource on drug delivery to the nervous system Provides a bridge for understanding across nervous system delivery-related physiology, drug delivery principles. and the methodologies that underlie the various methods of drug distribution (with clinical application) Written for a broad audience of researchers, clinicians and advanced graduate students in neuroscience, neurology, neurosurgery, pharmacology, radiology and psychiatry

Clinical Trials Design in Operative and Non Operative Invasive Procedures

Clinical Trials Design in Operative and Non Operative Invasive Procedures
Author: Kamal M.F. Itani,Domenic J. Reda
Publsiher: Springer
Total Pages: 495
Release: 2017-05-16
ISBN 10: 3319538772
ISBN 13: 9783319538778
Language: EN, FR, DE, ES & NL

Clinical Trials Design in Operative and Non Operative Invasive Procedures Book Review:

The aim of this text is to provide the framework for building a clinical trial as it pertains to operative and non operative invasive procedures, how to get it funded and how to conduct such a trial up to publication of results The text provides all details of building a scientifically and ethically valid proposal, including how to build the infrastructure for a clinical trial and how to move it forward through various funding agencies. The text also presents various types of clinical trials, the use of implantable devices and FDA requirements, and adjuncts to clinical trials and interaction with industry Clinical Trials Design in Invasive Operative and Non Operative Procedures will be of interest to all specialists of surgery, anesthesiologists, interventional radiologists, gastroenterologists, cardiologists, and pulmonologists

Epigenetics and Neuroendocrinology

Epigenetics and Neuroendocrinology
Author: Dietmar Spengler,Elisabeth Binder
Publsiher: Springer
Total Pages: 264
Release: 2016-04-02
ISBN 10: 3319244930
ISBN 13: 9783319244938
Language: EN, FR, DE, ES & NL

Epigenetics and Neuroendocrinology Book Review:

The field of neuroendocrinology has extended from the initial interest in the hypothalamic control of pituitary secretion to embrace multiple reciprocal interactions between the central nervous system and endocrine systems in the coordination of homeostasis and various physiological responses from adaptation to disease. Most recently, epigenetic mechanisms were recognized for their role in the development of the neuroendocrine axes as well as in the mediation of gene-environment interactions in stress-related psychiatry disorders.

The Biopsychosocial Model of Health and Disease

The Biopsychosocial Model of Health and Disease
Author: Derek Bolton,Grant Gillett
Publsiher: Springer
Total Pages: 149
Release: 2019-03-28
ISBN 10: 3030118991
ISBN 13: 9783030118990
Language: EN, FR, DE, ES & NL

The Biopsychosocial Model of Health and Disease Book Review:

This open access book is a systematic update of the philosophical and scientific foundations of the biopsychosocial model of health, disease and healthcare. First proposed by George Engel 40 years ago, the Biopsychosocial Model is much cited in healthcare settings worldwide, but has been increasingly criticised for being vague, lacking in content, and in need of reworking in the light of recent developments. The book confronts the rapid changes to psychological science, neuroscience, healthcare, and philosophy that have occurred since the model was first proposed and addresses key issues such as the model’s scientific basis, clinical utility, and philosophical coherence. The authors conceptualise biology and the psychosocial as in the same ontological space, interlinked by systems of communication-based regulatory control which constitute a new kind of causation. These are distinguished from physical and chemical laws, most clearly because they can break down, thus providing the basis for difference between health and disease. This work offers an urgent update to the model’s scientific and philosophical foundations, providing a new and coherent account of causal interactions between the biological, the psychological and social.

Practical Guide to Transcranial Direct Current Stimulation

Practical Guide to Transcranial Direct Current Stimulation
Author: Helena Knotkova,Michael A. Nitsche,Marom Bikson,Adam J. Woods
Publsiher: Springer
Total Pages: 651
Release: 2019-01-23
ISBN 10: 3319959484
ISBN 13: 9783319959481
Language: EN, FR, DE, ES & NL

Practical Guide to Transcranial Direct Current Stimulation Book Review:

This book provides a comprehensive overview on Transcranial Direct Current Stimulation (tDCS) and the clinical applications of this promising technique. Separated into three parts, the book begins with basic principles, mechanisms and approaches of tDCS. This is followed by a step-by-step practicum, methodological considerations and ethics and professional conduct pertaining to this novel technique. Chapters are authored by renowned experts who also direct and plan tDCS educational events worldwide. Bridging the existing gap in instructional materials for tDCS while addressing growing interest in education in this field, professionals within a broad range of medical disciplines will find this text to be an invaluable guide.

The Neurobiology of Childhood

The Neurobiology of Childhood
Author: Susan L. Andersen,Daniel S. Pine
Publsiher: Springer
Total Pages: 370
Release: 2014-05-13
ISBN 10: 3642549136
ISBN 13: 9783642549137
Language: EN, FR, DE, ES & NL

The Neurobiology of Childhood Book Review:

During the past years there has been rapid progress in the understanding of how early life stress impacts psychopathology in children. The first two parts of this book present the basic principles of brain development and describe the most important neuronal systems. This includes systems involved in emotion processing, cognitive control, and social processes. These first two general sections are followed by an overview about recent research on various neuronal and psychiatric disorders, where environmental exposures and altered brain development play an important role: sleep, autism, ADHD and other developmental forms of psychopathology.

The Health Effects of Cannabis and Cannabinoids

The Health Effects of Cannabis and Cannabinoids
Author: National Academies of Sciences, Engineering, and Medicine,Health and Medicine Division,Board on Population Health and Public Health Practice,Committee on the Health Effects of Marijuana: An Evidence Review and Research Agenda
Publsiher: National Academies Press
Total Pages: 486
Release: 2017-03-31
ISBN 10: 0309453070
ISBN 13: 9780309453073
Language: EN, FR, DE, ES & NL

The Health Effects of Cannabis and Cannabinoids Book Review:

Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management
Author: M. Mohamed Essa,M. Walid Qoronfleh
Publsiher: Springer Nature
Total Pages: 693
Release: 2020-01-31
ISBN 10: 3030304027
ISBN 13: 9783030304027
Language: EN, FR, DE, ES & NL

Personalized Food Intervention and Therapy for Autism Spectrum Disorder Management Book Review:

The book focuses on implications of traditional and processed foods for autism spectrum disorder (ASD) intervention and management. Numerous phytonutrients and pharmacologically active compounds in edible natural products and diet could influence and offer protection to neuronal dysfunction that occurs due to ASD. The neuroprotective effects of various fruits, vegetables, nuts and seeds phytochemicals, and other natural bioactive ingredients against ASD and related conditions are discussed. Topics such as the possible neuroprotective mechanism of action of these foods and the therapeutic role of antioxidants in relation to ASD are addressed. This book also highlights the scope of using anti-inflammatory agents and antioxidants to promote neurogenesis and improve other symptoms in ASD. It emphasizes personalized nutritional approaches with dietary management of neurodevelopmental disorders/ASD cases. Information in this book is relevant to researchers in the field of complementary and alternative medicine, nutraceuticals, neuroscience, agriculture, nutrition, and food science. This volume is beneficial to students of varying levels, and across multiple disciplines.

Evidence based Psychotherapy

Evidence based Psychotherapy
Author: Carol D. Goodheart,Alan E. Kazdin,Robert J. Sternberg
Publsiher: Amer Psychological Assn
Total Pages: 295
Release: 2006
ISBN 10:
ISBN 13: UOM:39015064095675
Language: EN, FR, DE, ES & NL

Evidence based Psychotherapy Book Review:

This book engages the voices of a broad range of clinical researchers, practitioners, educators, and public policy advocates in a comprehensive discussion of the spectrum of issues and arguments in the current debate about EBP.