Neurological Modulation of Sleep

Neurological Modulation of Sleep
Author: Ronald Ross Watson,Victor R. Preedy
Publsiher: Academic Press
Total Pages: 430
Release: 2020-01-15
ISBN 10: 0128166592
ISBN 13: 9780128166598
Language: EN, FR, DE, ES & NL

Neurological Modulation of Sleep Book Review:

Neurological Modulation of Sleep provides readers with updated scientific reviews regarding the interaction between sleep and contributing factors, with special attention paid to the potential for neurological modulation of sleep via diet. This book expands the notion of diet and adds an element of physical activity and exercise as well as a chapter on caffeine and its effects on sleep. With 30+ international contributors, this book aims to provide readers with a unique global perspective on the role these factors plays in sleep architecture and its regulation by circadian biology and neurology. Sleep disorders have become an increasing problem plaguing more than 70 million Americans according to the American Sleep Association. There is a clear association between sleep disorder and a wide range of other human disorders –performance deficiencies, psychiatric illnesses, heart disease, obesity and more – but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes. Describes the impact of diet, caffeine and physical activity on sleep Reviews the neurology and metabolism of sleep Identifies what foods impact sleep and how Discusses the clinical use of nutraceuticals to improve sleep

Modulation of Sleep by Obesity Diabetes Age and Diet

Modulation of Sleep by Obesity  Diabetes  Age  and Diet
Author: Ronald Ross Watson
Publsiher: Academic Press
Total Pages: 408
Release: 2014-09-14
ISBN 10: 0124202403
ISBN 13: 9780124202405
Language: EN, FR, DE, ES & NL

Modulation of Sleep by Obesity Diabetes Age and Diet Book Review:

Sleep disorder is a rampant problem in the US, with over 40 million Americans currently diagnosed according to the NIH. There is a clear association between sleep disorder and a wide range of other human disorders –performance deficiencies, psychiatric illnesses, heart disease, obesity and more – but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes. This volume focuses on the interaction between sleep and these factors, with special attention being paid to the potential for neurological modulation of sleep via diet. The volume aid readers in understanding the role each of these factors plays in sleep architecture and its regulation by circadian biology and neurology. Aids in understanding the impact of age, diet, obesity and disease on sleep Offers focus on neurological changes that affect metabolism Explores diabetes induced sleep problems Aid to understanding the multifactorial causes of age-related sleep dysfunction Addresses selected studies of nutraceuticals affecting sleep for potential application clinically Discusses major impact on sleep disorders by caffeine and alcohol

Sleep Disorders and Sleep Deprivation

Sleep Disorders and Sleep Deprivation
Author: Institute of Medicine,Board on Health Sciences Policy,Committee on Sleep Medicine and Research
Publsiher: National Academies Press
Total Pages: 424
Release: 2006-10-13
ISBN 10: 0309101115
ISBN 13: 9780309101110
Language: EN, FR, DE, ES & NL

Sleep Disorders and Sleep Deprivation Book Review:

Clinical practice related to sleep problems and sleep disorders has been expanding rapidly in the last few years, but scientific research is not keeping pace. Sleep apnea, insomnia, and restless legs syndrome are three examples of very common disorders for which we have little biological information. This new book cuts across a variety of medical disciplines such as neurology, pulmonology, pediatrics, internal medicine, psychiatry, psychology, otolaryngology, and nursing, as well as other medical practices with an interest in the management of sleep pathology. This area of research is not limited to very young and old patientsâ€"sleep disorders reach across all ages and ethnicities. Sleep Disorders and Sleep Deprivation presents a structured analysis that explores the following: Improving awareness among the general public and health care professionals. Increasing investment in interdisciplinary somnology and sleep medicine research training and mentoring activities. Validating and developing new and existing technologies for diagnosis and treatment. This book will be of interest to those looking to learn more about the enormous public health burden of sleep disorders and sleep deprivation and the strikingly limited capacity of the health care enterprise to identify and treat the majority of individuals suffering from sleep problems.

Encyclopedia of Sleep

Encyclopedia of Sleep
Author: Anonim
Publsiher: Academic Press
Total Pages: 2736
Release: 2012-12-31
ISBN 10: 0123786118
ISBN 13: 9780123786111
Language: EN, FR, DE, ES & NL

Encyclopedia of Sleep Book Review:

In a world of 24-hour media saturation, sleep has become an increasingly fraught enterprise. The award-winning four-volume Encyclopedia of Sleep is the largest reference, either online or in print, on the subject of sleep. Written to be useful for the novice and the established researcher and clinician, Topic areas will include sleep across the life cycle and in other species, sleep and women, sleep and the elderly, pediatric sleep, sleep deprivation and loss, sleep mechanisms, sleep physiology and pathophysiology, sleep disorders, neurobiology, chronobiology, pharmacology, and impact of other disorders on sleep. Recognizing the many fields that are connected to sleep science, the editorial team has been carefully chosen to do justice to this highly interdisciplinary field of study. The steady growth of researchers and clinicians in the sleep field attests to the continued interest in the scientific study of sleep and the management of patients with sleep disorders, and anyone involved in this exciting field should find this work to be an invaluable reference. 2013 PROSE Award winner for Multivolume Reference in Science from the Association of American Publishers Thoroughly interdisciplinary: looks at sleep throughout the life cycle, with exceptional coverage of basic sleep concepts, the physiology of sleep as well as sleep disorders of all descriptions Excellent coverage of sleep and special populations, covering the lifespan, as well as gender and ethnic differences, among others Chapters focusing on sleep disorders are grouped under the broad categories classified in the ICSD-2 for clear organization so that the reader can effectively access the steps involved in diagnosing and treating these disorders Online version is linked both within the encyclopedia (to related content) and to external sources (such as primary journal content) so that users have easy access to more detailed information if needed

Local Aspects of Sleep and Wakefulness

Local Aspects of Sleep and Wakefulness
Author: Giulio Bernardi,Francesca Siclari,Michele Bellesi
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2020-03-24
ISBN 10: 2889635651
ISBN 13: 9782889635658
Language: EN, FR, DE, ES & NL

Local Aspects of Sleep and Wakefulness Book Review:

Rapid Eye Movement Sleep

Rapid Eye Movement Sleep
Author: Birendra N. Mallick,S. R. Pandi-Perumal,Robert W. McCarley,Adrian R. Morrison
Publsiher: Cambridge University Press
Total Pages: 329
Release: 2011-07-14
ISBN 10: 1139503782
ISBN 13: 9781139503785
Language: EN, FR, DE, ES & NL

Rapid Eye Movement Sleep Book Review:

Spanning over half a century of investigation into Rapid Eye Movement (REM) sleep, this volume provides comprehensive coverage of a broad range of topics in REM sleep biology. World renowned researchers and experts are brought together to discuss past and current research and to set the foundation for future developments. Key topics are covered in six sections from fundamental topics (historical context and general biology) to cutting-edge research on neuronal regulation, neuroanatomy and neurochemistry, functional significance and disturbance in the REM sleep generating mechanism. A reference source for all aspects of REM sleep research, it also incorporates chapters on neural modelling, findings from non-human species and interactions between brain regions. This is an invaluable resource, essential reading for all involved in sleep research and clinical practice.

The Neuropsychology of Sleep and Dreaming

The Neuropsychology of Sleep and Dreaming
Author: John S. Antrobus,Mario Bertini
Publsiher: Psychology Press
Total Pages: 329
Release: 1992
ISBN 10: 0805809252
ISBN 13: 9780805809251
Language: EN, FR, DE, ES & NL

The Neuropsychology of Sleep and Dreaming Book Review:

This volume describes how the conceptual and technical sophistication of contemporary cognitive and neuroscientific fields has enhanced the neurocognitive understanding of dreaming sleep. Because it is the only naturally-occurring state in which the active brain produces elaborate cognitive processes in the absence of sensory input, the study of dreaming offers a unique cognitive and neurophysiological view of the production of higher cognitive processes. The theory and research included is driven by the search for the most direct relationships linking the neurophysiological characteristics of sleepers to their concurrent cognitive experiences. The search is organized around three sets of theoretical models and the three classes of neurocognitive relationships upon which they are based. The contributions to this volume demonstrate that the field has begun to move in new directions opened up by the rapid advances in contemporary cognitive science, neuropsychology, and neurophysiology.

Hypothalamus in Health and Diseases

Hypothalamus in Health and Diseases
Author: Stavros Baloyannis,Jan Gordeladze
Publsiher: BoD – Books on Demand
Total Pages: 142
Release: 2018-12-05
ISBN 10: 1789844444
ISBN 13: 9781789844443
Language: EN, FR, DE, ES & NL

Hypothalamus in Health and Diseases Book Review:

The human hypothalamus, a small structure at the base of the brain, has strategic importance for the harmonic function of the human body. It controls the autonomic nervous system, neuroendocrine function, circadian and circannual rhythms, somatic activities, and behavior, and is situated at the borders between the brain and the body and the brain and the soul, meeting points for mind and body. The hypothalamus is involved in a wide range of higher mental functions, including attention, learning and reinforcement of mnemonic processes, emotional control, mood stability, and cognitive-emotional interactions. It also has a role to play in behavioral disorders, panic reactions, cluster headache, gelastic epilepsy, mental deficiency, periodic disorders, depression, autism, and schizophrenia, and in a substantial number of neurodegenerative diseases. It enlarges greatly the dimensions of the hypothalamic contribution in controlling psychosomatic equilibrium and retaining internal unity of the human existence.

Addictive Substances and Neurological Disease

Addictive Substances and Neurological Disease
Author: Ronald Ross Watson,Sherma Zibadi
Publsiher: Academic Press
Total Pages: 414
Release: 2017-02-18
ISBN 10: 0128092963
ISBN 13: 9780128092965
Language: EN, FR, DE, ES & NL

Addictive Substances and Neurological Disease Book Review:

Addictive Substances and Neurological Disease: Alcohol, Tobacco, Caffeine, and Drugs of Abuse in Everyday Lifestyles is a complete guide to the manifold effects of addictive substances on the brain, providing readers with the latest developing research on how these substances are implicated in neurological development and dysfunction. Cannabis, cocaine, and other illicit drugs can have substantial negative effects on the structure and functioning of the brain. However, other common habituating and addictive substances often used as part of an individual’s lifestyle, i.e., alcohol, tobacco, caffeine, painkillers can also compromise brain health and effect or accentuate neurological disease. This book provides broad coverage of the effects of addictive substances on the brain, beginning with an overview of how the substances lead to dysfunction before examining each substance in depth. It discusses the pathology of addiction, the structural damage resulting from abuse of various substances, and covers the neurobiological, neurodegenerative, behavioral, and cognitive implications of use across the lifespan, from prenatal exposure, to adolescence and old age. This book aids researchers seeking an understanding of the neurological changes that these substances induce, and is also extremely useful for those seeking potential treatments and therapies for individuals suffering from chronic abuse of these substances. Integrates current research on the actions of addictive substances in neurological disease Includes functional foods, such as caffeine beverages, that have habituating effects on the brain Provides a synopsis of key ideas associated with the consequences of addictive and habituating lifestyle substances

Dopamine and Sleep

Dopamine and Sleep
Author: Jaime M. Monti,S. R. Pandi-Perumal,S. Chokroverty
Publsiher: Springer
Total Pages: 286
Release: 2016-10-24
ISBN 10: 331946437X
ISBN 13: 9783319464374
Language: EN, FR, DE, ES & NL

Dopamine and Sleep Book Review:

This book offers a comprehensive but highly readable compilation of papers on the role of dopamine in sleep and sleep disorders. Leading experts in sleep medicine, psychiatry and neuroendocrinology provide a broad perspective on the field, from established theories to the latest research advances. Accordingly, it represents an interdisciplinary, cutting-edge guide for sleep disorder specialists, sleep researchers, psychiatrists, neurologists, pulmonologists, psychologists, and behavioral sleep medicine specialists.

Omega 3 Fatty Acids in Brain and Neurological Health

Omega 3 Fatty Acids in Brain and Neurological Health
Author: Ronald Ross Watson,Fabien De Meester
Publsiher: Elsevier
Total Pages: 496
Release: 2014-06-25
ISBN 10: 0124105475
ISBN 13: 9780124105478
Language: EN, FR, DE, ES & NL

Omega 3 Fatty Acids in Brain and Neurological Health Book Review:

Research has clearly established a link between omega-3 fatty acids and general health, particularly cardiovascular health. Omega-3 Fatty Acids in Brain and Neurological Health is the first book to focus exclusively on the role of omega-3 fatty acids on general brain health. The articles in this collection illustrate omega-3 fatty acids' importance in longevity, cognitive impairment, and structure and function of the brain's neurons. Research has established links between omega-3 fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis. This book encompasses some of the most recent research, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep, and neurodegenerative diseases. This collection helps to push research forward toward a complete understanding of omega-3 fatty acids' relationship to brain and neurological health. The first book-length collection of original research on the connection between omega-3 fatty acids and the brain Provides a comprehensive introduction to the state of research on omega-3 fatty acids and the brain and directions for future research A foundational collection for neuroscience, neurology, and nutrition research

Brain Mechanisms

Brain Mechanisms
Author: Anonim
Publsiher: Elsevier
Total Pages: 492
Release: 1963-01-01
ISBN 10: 9780080861258
ISBN 13: 0080861253
Language: EN, FR, DE, ES & NL

Brain Mechanisms Book Review:

Brain Mechanisms

The Neuroscience of Sleep

The Neuroscience of Sleep
Author: Robert Stickgold,Matthew P. Walker
Publsiher: Academic Press
Total Pages: 374
Release: 2010-05-22
ISBN 10: 9780123757227
ISBN 13: 0123757223
Language: EN, FR, DE, ES & NL

The Neuroscience of Sleep Book Review:

Sleep is the natural state of bodily rest, common to all mammals and birds and also seen in many reptiles, amphibians and fish. For most species, regular sleep is essential for survival, yet the specific purposes of sleep are still only partly clear and are the subject of intense research. This volume is comprised of the editors’ selection of the most relevant articles on sleep from the Encyclopedia of Neuroscience, resulting in the first comprehensive collection of introductory articles on the neuroscience of sleep. Articles explore sleep’s impact on neural functioning, sleep disorders, the relation between sleep and other clinical disorders, a look at sleep from a developmental perspective, and more. * Chapters offer impressive scope with topics addressing neural functioning, disorders, development, and more, carefully selected by one of the most preeminent sleep researchers * Richly illustrated in full color with over 100 figures * Contributors represent the most outstanding scholarship in the field, with each chapter providing fully vetted and reliable expert knowledge

Omega Fatty Acids in Brain and Neurological Health

Omega Fatty Acids in Brain and Neurological Health
Author: Ronald Ross Watson,Victor R. Preedy
Publsiher: Academic Press
Total Pages: 518
Release: 2019-06-12
ISBN 10: 0128152397
ISBN 13: 9780128152393
Language: EN, FR, DE, ES & NL

Omega Fatty Acids in Brain and Neurological Health Book Review:

Research has clearly established a link between omega fatty acids and general health, particularly cardiovascular health. Omega Fatty Acids in Brain and Neurological Health, Second Edition, illustrates the importance of omega-3 fatty acids in longevity, cognitive impairment and structure and function of the brain's neurons and also the adverse effects of omega-6 fatty acids on neurological function. This book encompasses some of the most recent research on the links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements on hippocampal neurogenesis, substantia nigra modulation, migraine headaches, the developing brain in animals, sleep and neurodegenerative diseases. This completely updated second edition focuses on the counterbalancing dietary and tissue omega-6 fatty acids as well as it studies the effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases. Provides a comprehensive introduction to omega-3 and omega-6 fatty acids in neurological health and directions for future research Features novel focus on the adverse effects of omega-6 fatty acids on neurological function and the counterbalancing of dietary and tissue omega-6 Illustrates the importance of omega-3 fatty acids in longevity and cognitive impairment Features new chapters on early effects in pregnancy and early infancy, animal model studies and autoimmune neurological diseases Discusses links between omega fatty acids and the developing brain, aging, dementia, Alzheimer's disease and multiple sclerosis, including the role of omega-3 fatty acid supplements

Gene Therapy in Neurological Disorders

Gene Therapy in Neurological Disorders
Author: Mingjie Li,B. Joy Snider
Publsiher: Academic Press
Total Pages: 450
Release: 2018-05-25
ISBN 10: 012809821X
ISBN 13: 9780128098219
Language: EN, FR, DE, ES & NL

Gene Therapy in Neurological Disorders Book Review:

Gene therapy has tremendous potential for the treatment of neurological disorders. There has been substantial progress in the development of gene therapy strategies for neurological disorders over the last two decades. Gene Therapy in Neurological Disorders thoroughly reviews currently available gene therapy tools and presents examples of their application in a variety of neurological diseases. The book begins with general reviews of gene therapy strategies with a focus on neurological disorders. The remainder of the chapters present approaches to specific neurological disorders. Each chapter gives an in-depth introduction to the relevant field before diving into the specific tool or application. The book aims to help investigators, students and research staff better understand the principles of gene therapy and its application in the nervous system. Provides background information and experimental details of gene therapy tools applied for neuroscience research and neurological disorders Covers a broad range of gene delivery and regulation tools, therapeutic agents, and target cells, including emerging new technologies such as CRISPR/Cas9 genome editing Discusses applications of gene therapy tools to neurological disorders including neurodegeneration, muscular dystrophy, trauma and chronic pain, and neoplastic diseases

Neuroinflammation

Neuroinflammation
Author: Alireza Minagar
Publsiher: Elsevier
Total Pages: 540
Release: 2010-12-17
ISBN 10: 9780123849144
ISBN 13: 0123849144
Language: EN, FR, DE, ES & NL

Neuroinflammation Book Review:

Inflammation is a central mechanism in many neurological diseases, including stroke, multiple sclerosis, and brain trauma as well as meningitis and contributes to the generation of pain. We are now beginning to understand the impact of the immune system on different nervous system functions and diseases, ranging from damage through tolerance to modulation and repair. This book discusses some of the more common neuro-inflammatory diseases. Topics covered include multiple sclerosis, optic neuritis and Susac syndrome. Comprehensive review of the latest developments in neuroinflammation Includes contributions from leading authorities

Orexin and Sleep

Orexin and Sleep
Author: Takeshi Sakurai,S.R. Pandi-Perumal,Jaime M. Monti
Publsiher: Springer
Total Pages: 410
Release: 2015-09-22
ISBN 10: 3319230786
ISBN 13: 9783319230788
Language: EN, FR, DE, ES & NL

Orexin and Sleep Book Review:

This volume is intended for neuropharmacologists, psychopharmacologists, pharmacologists, pharmacists, sleep researchers, translational neuroscience researchers, and other basic researchers and clinical scientists interested in an interdisciplinary approach to sleep medicine. The level of the book is aiming at CNS researchers, drug development scientists, basic and clinical sleep researchers, as well as senior medical students and fellows in psychiatry and neurology. Orexin and Sleep provides a unique resource, giving a comprehensive and highly readable summary of the basic concepts in orexin biology and pharmacology along with clinical applications in sleep medicine in general, and narcolepsy in particular.

Handbook of the Behavioral Neurobiology of Serotonin

Handbook of the Behavioral Neurobiology of Serotonin
Author: Christian P. Muller,Barry Jacobs
Publsiher: Academic Press
Total Pages: 836
Release: 2009-12-30
ISBN 10: 9780080878171
ISBN 13: 0080878172
Language: EN, FR, DE, ES & NL

Handbook of the Behavioral Neurobiology of Serotonin Book Review:

Serotonin (5-hydroxytryptamine, often cited as 5-HT) is one of the major excitatory neurotransmitter, and the serotonergic system is one of the best studied and understood transmitter systems. It is crucially involved in the organization of virtually all behaviours and in the regulation of emotion and mood. Alterations in the serotonergic system, induced by e.g. learning or pathological processes, underlie behavioural plasticity and changes in mood, which can finally results in abnormal behaviour and psychiatric conditions. Not surprisingly, the serotonergic system and its functional components appear to be targets for a multitude of pharmacological treatments - examples of very successful drugs targeting the serotoninergic system include Prozac and Zoloft. The last decades of research have not only fundamentally expanded our view on serotonin but also revealed in much more detail an astonishing complexity of this system, which comprises a multitude of receptors and signalling pathways. A detailed view on its role in basal, but also complex, behaviours emerged, and, was presented in a number of single review articles. Although much is known now, the serotonergic system is still a fast growing field of research contributing to our present understanding of the brains function during normal and disturbed behaviour. This handbook aims towards a detailed and comprehensive overview over the many facets of behavioural serotonin research. As such, it will provide the most up to date and thorough reading concerning the serotonergic systems control of behaviour and mood in animals and humans. The goal is to create a systematic overview and first hand reference that can be used by students and scholars alike in the fields of genetics, anatomy, pharmacology, physiology, behavioural neuroscience, pathology, and psychiatry. The chapters in this book will be written by leading scientists in this field. Most of them have already written excellent reviews in their field of expertise. The book is divided in 4 sections. After an historical introduction, illustrating the growth of ideas about serotonin function in behaviour of the last forty years, section A will focus on the functional anatomy of the serotonergic system. Section B provides a review of the neurophysiology of the serotonergic system and its single components. In section C the involvement of serotonin in behavioural organization will be discussed in great detail, while section D deals with the role of serotonin in behavioural pathologies and psychiatric disorders. The first handbook broadly discussing the behavioral neurobiology of the serotonorgic transmitter system Co-edited by one of the pioneers and opinion leaders of the past decades, Barry Jacobs (Princeton), with an international list (10 countries) of highly regarded contributors providing over 50 chapters, and including the leaders in the field in number of articles and citations: K. P. Lesch, T. Sharp, A. Caspi, P. Blier, G.K. Aghajanian, E. C. Azmitia, and others The only integrated and complete resource on the market containing the best information integrating international research, providing a global perspective to an international community Of great value not only for researchers and experts, but also for students and clinicians as a background reference

Neuroscience of Nicotine

Neuroscience of Nicotine
Author: Victor R. Preedy
Publsiher: Academic Press
Total Pages: 566
Release: 2019-03-20
ISBN 10: 0128130369
ISBN 13: 9780128130360
Language: EN, FR, DE, ES & NL

Neuroscience of Nicotine Book Review:

Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process. Integrates cutting-edge research on the pharmacological, cellular and molecular aspects of nicotine use, along with its effects on neurobiological function Discusses nicotine use as a component of dual-use and poly addictions and outlines numerous screening and treatment strategies for misuse Covers both the physical and psychological effects of nicotine use and withdrawal to provide a fully-formed view of nicotine dependency and its effects

Neuroendocrine Correlates of Sleep Wakefulness

Neuroendocrine Correlates of Sleep Wakefulness
Author: Daniel P. Cardinali,S. R. Pandi-Perumal
Publsiher: Springer Science & Business Media
Total Pages: 627
Release: 2010-03-14
ISBN 10: 9780387236926
ISBN 13: 0387236929
Language: EN, FR, DE, ES & NL

Neuroendocrine Correlates of Sleep Wakefulness Book Review:

As the title suggests, and unlike other existing books on sleep medicine, Neuroendocrine Correlates of Sleep/Wakefulness will be devoted primarily to endocrine regulation of the behavioral state control. It will address a wide spectrum of sleep./wakefulness phenomena (both animals and humans), including pathogenesis, diagnosis, and management. From molecular biology to applied clinical therapy, sleep research has been transformed in the last few years from a research backwater to an important interdisciplinary field. Anyone who regularly reads the literature on sleep, biological rhythms, or neuroendocrinology is aware that one of the subspecialties within sleep medicine, the neuroendocrine correlates of sleep/wakefulness, has in particular experienced a growth rate that is even faster than that of the field as a whole. To a significant extent this has been due to the introduction of new research technologies. The widespread adoption of a range of new methods in sleep research has opened a window into activities at the cellular and molecular level, which previously had been tightly closed. Consequently these activities are being characterized with a degree of precision and sensitivity that is without precedent. This volume invites the reader to explore the new vistas that have been opened onto the neuroendocrine frontier of sleep medicine. The editors have selectively identified a number of key articles having a citation frequency, which is considerably above the norm or which otherwise have contributed importantly to defining the neuroendocrine perspective. This new volume on Neuroendocrine Correlates of Sleep/Wakefulness is an up-to-date resource of research summaries and reviews written by major contributors to the fields of sleep, biological rhythms and neuroendocrinology. Its coverage is broad and its basic and clinical science reviews are detailed. In this volume, an international team of experts discuss their latest ideas, concepts, methods, and interpretations with supporting examples. This volume is intended for advanced students and specialists in psychobiology, neuroscience, neuroendocrinology, and psychiatry but might also be interest to anyone concerned with understanding the Neuroendocrine correlates of sleep/wakefulness. The contributions are directed more towards providing an integrated view of the field from the perspective of the authors, rather than being a compendium of recent results. The intent is to provide a reference book for recent and future workers in this and related areas of medicine and biology. Each topic in this volume has received the attention of a panel of authors who have responded to our request to review and place into perspective the major issues, which will undoubtedly confront newcomers to the field. The topics dealt with in Neuroendocrine correlates of Sleep/wakefulness are both diverse and complex. The editors hope that this volume will provide an authoritative summary of important issues in the neuroendocrine correlates of sleep/wakefulness. We also hope that it will motivate new researchers to join the quest for solutions to the problems that have been identified by our contributing authors.