Neurogenic Inflammation in Health and Disease
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Neurogenic Inflammation in Health and Disease
Author | : Gábor Jancsó |
Publsiher | : Elsevier |
Total Pages | : 346 |
Release | : 2009 |
ISBN 10 | : 0444532293 |
ISBN 13 | : 9780444532299 |
Language | : EN, FR, DE, ES & NL |
Morphological and functional studies revealed a complex system of primary sensory neurons which parallels the autonomic nervous system not only in its extent, but probably also in its significance. Neuropeptides released from activated nociceptive afferent nerves play a pivotal role in inflammatory reactions and pain, significantly modulate cardiac, vascular, respiratory, gastrointestinal and immune functions and influence the protective, restorative and trophic functions of somatic and visceral tissues. Several chapters of the book deal with the therapeutic potential of a new class of putative pain relieving agents acting through TRPV1, the capsaicin/vanilloid receptor, a specific ion channel which transmits pain. * Neurogenic inflammation in historical perspective * Cardiac protection by nociceptive afferents * Molecular mechanisms of nociception * Sensory mechanisms in migraine pathophysiology * Vagal signalling of visceral inflammation * Neurogenic mechanisms in arthritis * Therapeutic implications of vanilloid-type compounds
The Mast Cell in Health and Disease
Author | : Kaliner |
Publsiher | : CRC Press |
Total Pages | : 858 |
Release | : 1992-10-29 |
ISBN 10 | : 9780824787325 |
ISBN 13 | : 0824787323 |
Language | : EN, FR, DE, ES & NL |
Offers coverage of practical and theoretical implications of current research into mast cell biology, emphasizing the role of the mast cell in human diseases. The text covers all aspects of the mast cell from growth and differentiation to its function in such conditions as asthma and skin disease.
Nutraceuticals and the Skin Roles in Health and Disease
Author | : Jean Christopher Chamcheu,Deeba Nadeem Syed,G. Kerr Whitfield |
Publsiher | : MDPI |
Total Pages | : 224 |
Release | : 2018-10-08 |
ISBN 10 | : 3038971928 |
ISBN 13 | : 9783038971924 |
Language | : EN, FR, DE, ES & NL |
This book is a printed edition of the Special Issue "Nutraceuticals and the Skin: Roles in Health and Disease" that was published in Nutrients
The Brain and Host Defense
Author | : Anonim |
Publsiher | : Elsevier |
Total Pages | : 358 |
Release | : 2009-12-24 |
ISBN 10 | : 9780444535450 |
ISBN 13 | : 0444535454 |
Language | : EN, FR, DE, ES & NL |
It is now well recognized that the brain, and especially the hypothalamus, plays an important role in the regulation of immune reactions and inflammation. This book aims to review our current state of knowledge of this important field. Key historical findings are presented, and the reciprocal interactions between the brain and the immune system are examined. Particular emphasis is placed on inflammation, a critical host defense reaction that serves as an effector response for both the adaptive and innate immune systems. Mechanisms implicated in brain defense, as well as in more general host defense, are discussed. The regulatory influences of the brain on inflammatory responses are included with particular reference to the role of the hypothalamus, which is also the main director the hormonal regulation of immune/inflammatory. Gender-related differences in immune responsiveness, circadian modulator of immune responses, and evidence that behavioral conditioning (e.g. reward) of immune responses is possible are used as examples to reinforce the notion that the neuroendocrine system exerts a fundamental and complex regulatory influence on the immune system. * Presents timely issues such as immunological aspects of the blood-brain-barrier and the role of inflammatory mediators in the evolution of strokes and degenerative diseases * Includes analysis of the role of the brain in the adaptive responses to disease * Evaluates the argument that further knowledge of the influence of the brain on the immune system will provide new insights to the pathophysiology infectious and autoimmune diseases
Transient Receptor Potential Channels
Author | : Md. Shahidul Islam |
Publsiher | : Springer Science & Business Media |
Total Pages | : 1095 |
Release | : 2011-02-04 |
ISBN 10 | : 9789400702653 |
ISBN 13 | : 9400702655 |
Language | : EN, FR, DE, ES & NL |
Transient Receptor Potential Channels offers a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. This single book covers TRP channels of yeasts, flies, fishes frogs and humans. And from the biophysics of primary thermo-sensory events in cells to the thermosensation at whole organism level, from physiology of pain to the development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginner and expert alike. It includes crucial background information, critical analysis of cutting edge research, and ideas and thoughts for numerous testable hypotheses. It also shows directions for future research in this highly dynamic field. It is a book readers will be just as eager to give to others as keep for themselves.
Stress in Health and Disease An Issue of Psychiatric Clinics of North America
Author | : Daniel L. Kirsch |
Publsiher | : Elsevier Health Sciences |
Total Pages | : 281 |
Release | : 2014-12-27 |
ISBN 10 | : 0323326773 |
ISBN 13 | : 9780323326773 |
Language | : EN, FR, DE, ES & NL |
Stress in the DSM is referred to only in the sense of post traumatic stress disorder (PTSD). However, some research studies estimate up to two thirds of illnesses seen by general practitioners are ‘stress related’–GI problems, sleep disturbance, mental concentration, headaches, fatigue, shortness of breath, high blood pressure, dermatitis, illnesses from lowered immune system, and vague aches and pains – all can be symptoms and outcomes of the elusive stress factor. This issue of Psychiatric Clinics of North America discusses the scientific medical facets of stress, written by mental health and medical practitioners. It looks at the brain-body connection of stress – what the body does to result in stress and varying results stress has on the body. This fascinating cross-discipline look at stress is intended for psychiatrists, general practitioners, cardiologists, GI specialists, neurologists, sleep medicine specialists, respiratory specialists, and others who diagnose and treat patients with stress suspected as part of the illness equation or with self-reported stress. Topics include: Measurement of stress; Anxiety and stress-how they work together; Relationship between genetics and stress; Role of glia in stress; Sleep and stress; Diet and stress; Supplements and stress; Effect of severe stress on early brain development, attachment, and emotions; Role of stress and fear on the development of psychopathology; Expressions of stress in psychiatric illness; Dermatologic manifestations of stress in normal and psychiatric populations; Humor and the psychological buffers of stress; Stress expression in children and adolescents; Stress in service members; Stress in the geriatric population.
Environmental Health Perspectives
Author | : Anonim |
Publsiher | : Anonim |
Total Pages | : 329 |
Release | : 1993 |
ISBN 10 | : |
ISBN 13 | : UCR:31210010905816 |
Language | : EN, FR, DE, ES & NL |
The Role of Neutrophil activating Mediators in Canine Health and Disease
Author | : Mads Krogsgaard Thomsen |
Publsiher | : Anonim |
Total Pages | : 223 |
Release | : 1991 |
ISBN 10 | : 9788789468020 |
ISBN 13 | : 8789468023 |
Language | : EN, FR, DE, ES & NL |
The American Review of Respiratory Disease
Author | : Anonim |
Publsiher | : Anonim |
Total Pages | : 329 |
Release | : 1993-11 |
ISBN 10 | : |
ISBN 13 | : CORNELL:31924073385779 |
Language | : EN, FR, DE, ES & NL |
Includes Abstracts section, previously issued separately.
Murray and Nadel s Textbook of Respiratory Medicine E Book
Author | : Robert J. Mason,V.Courtney Broaddus,Thomas R Martin,Talmadge E King,Dean Schraufnagel,John F. Murray,Jay A. Nadel |
Publsiher | : Elsevier Health Sciences |
Total Pages | : 2440 |
Release | : 2010-06-09 |
ISBN 10 | : 1437735533 |
ISBN 13 | : 9781437735536 |
Language | : EN, FR, DE, ES & NL |
Murray and Nadel’s Textbook of Respiratory Medicine has long been the definitive and comprehensive pulmonary disease reference. Robert J. Mason, MD now presents the fifth edition in full color with new images and highlighted clinical elements. The fully searchable text is also online at www.expertconsult.com, along with regular updates, video clips, additional images, and self-assessment questions. This new edition has been completely updated and remains the essential tool you need to care for patients with pulmonary disease. Consult this title on your favorite e-reader, conduct rapid searches, and adjust font sizes for optimal readability. Compatible with Kindle®, nook®, and other popular devices. Master the scientific principles of respiratory medicine and its clinical applications. Work through differential diagnosis using detailed explanations of each disease entity. Learn new subjects in Pulmonary Medicine including Genetics, Ultrasound, and other key topics. Grasp the Key Points in each chapter. Search the full text online at expertconsult.com, along with downloadable images, regular updates, more than 50 videos, case studies, and self-assessment questions. Consult new chapters covering Ultrasound, Innate Immunity, Adaptive Immunity, Deposition and Clearance, Ventilator-Associated Pneumonia. Find critical information easily using the new full-color design that enhances teaching points and highlights challenging concepts. Apply the expertise and fresh ideas of three new editors—Drs. Thomas R. Martin, Talmadge E. King, Jr., and Dean E. Schraufnagel. Review the latest developments in genetics with advice on how the data will affect patient care.
NGF and Related Molecules in Health and Disease
Author | : L. Aloe,L. Calza |
Publsiher | : Elsevier |
Total Pages | : 570 |
Release | : 2003-12-10 |
ISBN 10 | : 9780080497501 |
ISBN 13 | : 0080497500 |
Language | : EN, FR, DE, ES & NL |
The book highlights different aspects of current understanding of neurotrophin-receptor signal transduction pathways, including the signaling endosome hypothesis. Findings on the synaptotrophic potential of NGF and related neurotrophins, neurotrophin involvement in neuronal stem cell biology, biological activity of the NGF precursor proNGF, and nociception- and antinociception-associated activity of NGF and/or BDNF are also presented and discussed. Several chapters deal with the involvement of various neurotrophins in the control of different nonneuronal processes, such as immune, inflammatory and allergic reactions, tissue repair and wound healing. The findings showed that neurotrophins play important roles in the pathobiology of a surprising variety of seemingly unrelated non-neurological diseases, including bronchial asthma, rheumatoid arthritis, systemic sclerosis, hair growth disorders, psoriasis, corneal and skin ulcers, atherosclerosis, metabolic syndrome, crush syndrome, and Behçet's disease. There are also chapters on the involvement of NGF and related molecules in neurological diseases, including Huntington's disease, the multiple sclerosis-like model of experimental allergic encephalomyelitis, peripheral neuropathies, neuroblastoma, Parkinson's disease, Alzheimer's disease, and even motion sickness syndrome, also psychiatric disorders, including depression and schizophrenia. Finally, potential important therapeutic benefits are presented, for diabetic neuropathy, gastrointestinal dysmotility, CNS neurodegenerative disease, spinal cord injuries, cutaneous and corneal ulcers, as well as peripheral ischemic vasculopathy.
Muscarinic Receptors in Airways Diseases
Author | : Johan Zaagsma,Herman Meurs,Ad F. Roffel |
Publsiher | : Springer Science & Business Media |
Total Pages | : 266 |
Release | : 2001 |
ISBN 10 | : 9783764359881 |
ISBN 13 | : 3764359889 |
Language | : EN, FR, DE, ES & NL |
What are the different muscarinic acetylcholine receptor subtypes and how are they distributed in the airways and molecular signalling mechanisms? What is their function in neurogenic and non-neurogenic control of the airways and in inflammatory mechanisms? How is their gene expression regulated? The great importance of muscarinic acetylcholine receptors for the pathophysiology and treatment of chronic inflammatory obstructive airways diseases calls for a comprehensive and integrated overview of the current knowledge to address such questions, to discuss the role of these receptor subtypes in diseases such as asthma and COPD, and to present novel perspectives on antimuscarinic drug development. The present book is the worthy result of this need. It points out innovative insights into the hitherto poorly understood role of postjunctional muscarinic M2 receptors in airway smooth muscle contraction and sheds some light on the novel concepts of antimuscarinic drug development, with special reference to the l
Cell Surface Peptidases in Health and Disease
Author | : A.J. Kenny,C.M. Boustead |
Publsiher | : Taylor & Francis |
Total Pages | : 384 |
Release | : 1997-07 |
ISBN 10 | : |
ISBN 13 | : CORNELL:31924080084951 |
Language | : EN, FR, DE, ES & NL |
Cells bristle with a battery of surface enzymes, of which the peptidases form the largest and best studied group. These ectopeptidases play crucial roles in many diverse biological functions, including the termination of peptide signals in the nervous system and at peripheral sites. Some of their key physiological roles, such as those of angiotensin- and endothelin-converting enzymes in generating vasoconstrictive agents and endopeptidase-24.11 in activating natriuretic peptides, enkephalins and tachykinins, have made them prime targets for the pharmaceutical industry. Interest among immunologists and haematologists was aroused when several were shown to be identical to cell-surface markers (CD antigens) on human leukocytes. Virologists have been excited to find that some double as receptors for certain viruses.
Immune System Diseases New Insights for the Healthcare Professional 2011 Edition
Author | : Anonim |
Publsiher | : ScholarlyEditions |
Total Pages | : 188 |
Release | : 2012-01-09 |
ISBN 10 | : 1464901163 |
ISBN 13 | : 9781464901164 |
Language | : EN, FR, DE, ES & NL |
Immune System Diseases: New Insights for the Healthcare Professional: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Immune System Diseases. The editors have built Immune System Diseases: New Insights for the Healthcare Professional: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Immune System Diseases in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Immune System Diseases: New Insights for the Healthcare Professional: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.
The Periodontal Ligament in Health and Disease
Author | : B. K. B. Berkovitz,B. J. Moxham,Hubert N. Newman |
Publsiher | : Anonim |
Total Pages | : 446 |
Release | : 1995 |
ISBN 10 | : |
ISBN 13 | : UOM:39015034413107 |
Language | : EN, FR, DE, ES & NL |
Cough An Interdisciplinary Problem An Issue of Otolaryngologic Clinics E Book
Author | : Kenneth W. Altman,Richard S. Irwin |
Publsiher | : Elsevier Health Sciences |
Total Pages | : 237 |
Release | : 2010-03-17 |
ISBN 10 | : 1455700517 |
ISBN 13 | : 9781455700516 |
Language | : EN, FR, DE, ES & NL |
Both acute and chronic cough are responsible for a significant number of ambulatory medical visits annually. The recent comprehensive understanding that “cough is a reflection of underlying disease pays tribute to the multifactorial causes, as well recognition of the respiratory and upper digestive tract as a “physiologic unit. This publication highlights the advances made in managing cough and brings these to otolaryngology practitioners in a concise forum, as well as presenting issues of special interest to laryngologists such as paradoxical vocal fold motion, disordered breathing, irritable larynx, evolution of the vagus as a protective circuit, the importance of cough in deglutition, and surgical interventions. Some of the topics include: The cough reflex, sensory receptors, and neurogenic mediators; Mucus and mucins; Cough and Swallowing dysfunction; Cough due to asthma, cough-variant asthma, and nonasthmatic eosinophilic bronchitis; Occupational, environmental, and irritant induced cough; Pharmacologic management; Unexplained cough; Cough in the pediatric population; and Rhinogenic laryngitis, cough and the unified airway; among others.
Ocular Immunology in Health and Disease
Author | : Steven B. Koevary |
Publsiher | : Butterworth-Heinemann Medical |
Total Pages | : 183 |
Release | : 1999 |
ISBN 10 | : |
ISBN 13 | : UOM:39015046898501 |
Language | : EN, FR, DE, ES & NL |
Ocular Immunology in Health and Disease is designed to provide the reader with a review of the basic concepts in immunology. A thorough introductory section is followed by a discussion of the unique attributes of ocular immunity and the basis of ocular immune privilege. * - Provides a basic introduction to immunology for the student and practitioner * - Detailed and thorough introduction and discussion included in each chapter * - Describes unique attributes of ocular immunity and the basis of ocular immune privilege
An Introduction to Neurotransmission in Health and Disease
Author | : Peter Riederer,Peter Rieder,Nicolas Kopp,John Pearson |
Publsiher | : Oxford University Press, USA |
Total Pages | : 398 |
Release | : 1990 |
ISBN 10 | : |
ISBN 13 | : UOM:39015018521685 |
Language | : EN, FR, DE, ES & NL |
This volume provides an in-depth exploration of the neuroanatomical, neurochemical, and neurophysiological aspects of clinical disease syndromes. It will be of value to neuroscientists wanting to measure the importance of their work in the interpretation of the disease process, to clinicians seeking a greater understanding of the rationale for the measures they employ, and to pharmaceutical researchers needing information on drugs used in neurology, neurosurgery, and psychiatry. Widely scattered information on the roles of neurotransmitters in normal physiological functions is brought together in this easy-to-use reference. source.
Mast Cell and Basophil Differentiation and Function in Health and Disease
Author | : Stephen J. Galli,Karl Frank Austen |
Publsiher | : Raven Press (ID) |
Total Pages | : 348 |
Release | : 1989 |
ISBN 10 | : |
ISBN 13 | : UOM:39015014484169 |
Language | : EN, FR, DE, ES & NL |
Pain Management E Book
Author | : Steven D. Waldman |
Publsiher | : Elsevier Health Sciences |
Total Pages | : 1248 |
Release | : 2011-06-09 |
ISBN 10 | : 1437736033 |
ISBN 13 | : 9781437736038 |
Language | : EN, FR, DE, ES & NL |
Regarded as the premiere clinical reference in its field, Pain Management, 2nd Edition, edited by noted pain authority Dr. Steven Waldman, provides comprehensive, practical, highly visual guidance to help you effectively apply the most recent evidence-based advances in pain management. This popular text has been updated with 13 new chapters that include the latest information on interventional and ultrasound-guided techniques, acute regional pain nerve blocks, and more. A user-friendly format with lavish illustrations enables you to access trusted guidance quickly...and apply the information easily...to bring effective pain relief to your patients. Tap into the experience of the book’s editor, Dr. Steven D. Waldman—author of numerous groundbreaking pain management references—and a diverse collection of leading international experts, many of whom are new to this edition. Effectively diagnose and manage any type of pain by implementing the latest, evidence-based approaches including interventional and ultrasound-guided techniques, and acute regional pain nerve blocks. Keep up with the most essential and latest topics with fully revised chapters and 13 new chapters that include information on central pain modulation, ultrasound-guided procedures, myelopathy, and more. Find the critical answers you need quickly and easily thanks to a templated format, with all content solely reviewed by Dr. Waldman to insure consistency throughout. Make more accurate diagnoses and perform nerve blocks successfully with unmatched guidance from 1100 full-color, large-scale illustrations.