Neurodevelopmental Disorders

Neurodevelopmental Disorders, the latest release in the Comprehensive Developmental Neuroscience series, presents the most thorough coverage available, addressing all aspects on how the nervous system and its components develop. This book brings together the latest research in this rapidly evolving field, with section editors discussing the technological advances that are enabling the pursuit of new research on brain development. This volume focuses on neurodevelopmental disorders in humans and experimental organisms. Particular attention is paid to the effects of abnormal development and on new psychiatric/neurological treatments being developed based on our increased understanding of developmental mechanisms. Features leading experts in various subfields as section editors and article authors Presents articles that have been peer reviewed to ensure accuracy, thoroughness and scholarship Covers disorders of the nervous system that arise through defects in neural development

From autism to ADHD to learning disabilities, a guide for all teachers to this constellation of disorders. Developmental deficits in learning and communication in young children are defined as neurodevelopmental disorders. This constellation, newly defined in the DSM-5, represents a range of issues that educators must address. Neurodevelopmental Disorders: A Definitive Guide for Educators provides extensive and practical information to a range of professionals, and to all others who are interested in the complex and often misunderstood disabilities that fall within the general medical and psychological diagnostic categories of neurodevelopmental disability. Noted psychologist and educator Dr. Frank E. Vargo provides a comprehensive overview of neurodevelopmental deficits and disabilities, as well as of their related learning and cognitive processes, with a strong focus on educational considerations, applications, and relevance across academic areas and with a mind to global educational models. Well researched and accessibly written, this book is an up-to-date and authoritative reference to all of the educational and clinical topics in the diagnostic categories of neurodevelopmental disorder. This informative book will provide a primary reference source for all educators, school and clinical psychologists, clinical mental health counselors and therapists, special education and medical professionals, and parents of children with special needs.

Neurodevelopmental Disorders in Children and Adolescents provides an innovative perspective on developmental disorders in youth, one focused on embracing and working with the "messiness" and many variables at play in child and adolescent development. The volume’s approach is aligned with the NIMH Research Domain Criteria project, which hopes to move away from categorical diagnosis toward multidimensional analysis. Each chapter focuses on a particular aspect of development, cluster of diagnoses, or clinical concern. The book also emphasizes humility, an awareness of diversity and difference without stigma, and support for collaborative and integrative healthcare. This is an essential volume for practitioners hoping to improve how they evaluate and treat developmental disorders in children.

Interest in the field of neurodevelopmental disorders has grown exponentially in recent years across a range of disciplines, including psychology, psychiatry, education and neuroscience. The research itself has become more sophisticated, using multidisciplinary methods to probe interdisciplinary questions. Neurodevelopmental Disorders: Research Challenges and Solutions provides a thorough overview of the key issues involved in researching neurodevelopmental disorders. The volume includes 14 chapters, arranged over three sections. Chapters in the first section address general research challenges for the study of neurodevelopmental disorders. The second section draws upon specific disorders (such as Williams syndrome, Autism Spectrum Disorders, Down Syndrome, Fragile X Syndrome, ADHD, and Language Disorders) to consider the syndrome-specific issues or challenges that may be crucial to advancing our understanding of aspects of cognition and behavior associated with them. The final section considers how research evidence may be translated into practice to begin making an impact upon the lives of individuals who have neurodevelopmental disorders and their families. Each chapter in the book also includes ‘practical tips’ for either conducting research with individuals who have neurodevelopmental disorders or considering wider practical issues. The book will be indispensable reading for advanced students, researchers, and practitioners in the fields of developmental psychology, developmental psychopathology, special needs education, neuropsychology, and neurodevelopmental disorders.

Neurodevelopmental disorders arise from disturbances to various processes of brain development, which can manifest in diverse ways. They encompass many rare genetic syndromes as well as common, heritable conditions such as intellectual disability, autism, ADHD, schizophrenia and many types of epilepsy. The Genetics of Neurodevelopmental Disorders examines recent revolutionary advances in our understanding of the genetics of these disorders, exploring both basic discoveries and the translation of new findings into the clinical setting. The book begins by examining the genetic architecture and etiology of neurodevelopmental disorders. It describes the striking recent progress in identifying pathogenic mutations, which are grouped here based on the neurodevelopmental processes impacted. Subsequent chapters consider the use of cellular and animal models to elucidate the cascading consequences of such mutations, from molecular and cellular levels to emergent effects on neural circuits, brain systems and subsequent psychological development. The text concludes by examining the important clinical implications of the recent advances in the field, from recognition of the genetic causes in individual patients to development of new treatments and interventions. A timely synthesis, The Genetics of Neurodevelopmental Disorders is a unique and essential resource for neuroscientists, geneticists, neurologists and psychiatrists and an accessible and up-to-date overview for medical and science students.

Content Description #"A Bradford Book."#Includes bibliographical references and index.

We have great pleasure to present the latest extension of the European Institute of Health Care book series. This volume is devoted to neurodevelopmental d- orders. Again, we had the privilege to be able to work with reknowned experts who have agreed to contribute to this endeavour. The book comprises a number of topics related to psychosocial and motor development and is exemplary with regard to its comprehensiveness, as reviews of the topics presented are generally not available in a single publication. It starts with a timely and critical discussion of the genetics of attention deficit hyperactivity disorder by Dr. Buitelaar in which prospects and challenges of this approach are outlined. The next chapter by Drs. Nicolson and Fawcett deals with dyslexia and its relationship to cerebellar function providing a framework that can explain motor, speed, and phonological deficits in a unified approach. Diagnostic and treatment aspects of speech development disorders are the focus of Dr. Zorowka’s contribution in which, among other issues, the necessity of mul- professional cooperation is stressed. Dr. Sigmundsson then focuses on disorders of motor development. 6-10 % of children have motor competence well below the norm, which often persist. The clumsy child syndrome must be seen and treated as a neurological dysfunction. The relationship between tic disorders and obsessive compulsive disorder, two disturbances generally treated by different medical specialists, namely neurologists or psychiatrists, is then reviewed by Drs.

This cutting-edge book brings advances in genetics, neurobiology, and psychopharmacology to the clinic to enhance treatment for neurodevelopmental disorders. Significant progress has been made in identifying the neurobiological mechanisms of several disorders and targeted treatments are modifying the outcome of these disorders. However, the ability to utilize this knowledge has not been summarized in one place for the practicing clinician. This book will fill that gap by providing the theoretical underpinnings and the latest advances in targeted treatments. Several neurodevelopmental disorders are reviewed in detail including clinical features and behavioral phenotypes, standard treatments and new targeted treatments based on the latest advances in neurobiology and the animal model studies that have led to new treatments. The disorders covered include psychiatric disorders: schizophrenia, depression, autism and ADHD; single gene disorders including Tuberous Sclerosis, Fragile X Syndrome and fragile X- associated disorders, Angelman Syndrome, PKU, and Muscular Dystrophies; and complex genetic disorders such as Down syndrome. This book also highlights the commonalities across disorders and new genetic and molecular concepts in an easy to read format. This is a very exciting time for new targeted treatments and this volume is a landmark treatise on this new age of treatment.

Autism and Other Neurodevelopmental Disorders gathers and organizes the most recent information in this important and rapidly expanding field into a clinically useful volume that will enable clinicians, patients, and families to understand these disorders and make sound treatment decisions in light of recent research. The editors, as well as most of the chapter authors, are faculty or former trainees at the prestigious Medical Investigation of Neurodevelopmental Disorders (MIND) Institute at UC-Davis, a collaborative international research center committed to the awareness, understanding, prevention, care, and cure of neurodevelopmental disorders, including autism spectrum disorders, ADHD, learning disorders, and more. Each chapter presents signs and symptoms; epidemiology and etiology; diagnostic approaches; evidence based interventions; and reviews of promising research. By focusing on the range of neurodevelopmental disorders commonly seen and managed by both primary and subspecialist health care professionals. Autism and Other Neurodevelopmental Disorders explains cutting-edge research and advances in clinical care, and assembles them into a single, indispensable volume.

Short-term or working memory - the capacity to hold and manipulate information mentally over brief periods of time - plays an important role in supporting a wide range of everyday activities, particularly in childhood. Children with weak working memory skills often struggle in key areas of learning and, given its impact on cognitive abilities, the identification of working memory impairments is a priority for those who work with children with learning disabilities. Working Memory and Neurodevelopmental Disorders supports clinical assessment and management of working memory deficits by summarising the current theoretical understanding and methods of assessment of working memory. It outlines the working memory profiles of individuals with a range of neurodevelopmental disorders (including Down's syndrome, Williams syndrome, Specific Language Impairment, and ADHD), and identifies useful means of alleviating the anticipated learning difficulties of children with deficits of working memory. This comprehensive and informative text will appeal to academics and researchers in cognitive psychology, neuropsychology and developmental psychology, and will be useful reading for students in these areas. Educational psychologists will also find this a useful text, as it covers the role of working memory in learning difficulties specific to the classroom.

Neurotechnology and Brain Stimulation in Pediatric Psychiatric and Neurodevelopmental Disorders provides a comprehensive overview of neurotechnological devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents. Many neuropsychiatric disorders are covered such as Autism Spectrum Disorder, ADHD, Depression, Tourette’s Syndrome, and OCD. Different device-based treatments are discussed such as Transcranial Magnetic Stimulation, Transcranial Direct Current Stimulation, Deep Brain Stimulation, Chronotherapy, and Neurofeedback. Provides an overview of neuromodulatory devices as potential treatments for psychiatric and neurodevelopmental disorders in children and adolescents Gives evidence-based recommendations for non-drug interventions that may be effective for treatment options Discusses different neuromodulatory treatment options, including TMS, tDCS, DBS, chronotherapy and neurofeedback

This book addresses a broad range of biologically based disorders that affect children's learning and development. Leading authorities review the genetics of each disorder; its course and outcome; associated developmental, cognitive, and psychosocial challenges; and what clinicians and educators need to know about effective approaches to assessment and intervention. --from publisher description

This book opens with a discussion of neurodiversity and an elaboration of the diagnosis of autism. It then examines factors correlating with autism, including sex bias, month of birth, migration and impact of infant feeding. The next section is on the impact of autism. The neurobiology and genetic section deals with epigenetics and intracellular pathways associated with etiology. The development and behaviour section deals with proprioceptive profiles and joint attention in autism. The final section focuses on interventions including mindfulness, animal assisted activity, social/cultural perspective on autism intervention and physical activity. The book is relevant to all professionals and researchers working with persons with autism, including psychiatrists/psychologists, speech and language therapists, occupational therapists, teachers, nurses and care workers.

This book reviews strategies for assessing and treating pediatric obesity in children with neurodevelopmental disorders (ND). It synthesizes empirical findings and clinical strategies to offer the latest knowledge in key areas, including risk factors, physical activity, nutrition, treatment planning, goal-setting, and engagement with patients. A four-stage treatment model presents clinical guidance in triaging treatment and tailoring interventions to children’s changing medical, behavioral, emotional, and cognitive needs. The book complements current pediatric ND literature by presenting clear guidelines for integrating treatment for obesity into existing treatment of these young patients. Topics featured in this book include: The effect of neurodevelopmental disorders on the assessment of obesity in children. The impact of developmental delays on physical activities and health behaviors. Strategies for promoting weight management goals in pediatric ND. Suggestions on how to engage and support families and caregivers. The role of prevention in weight management within pediatric ND. Assessing and Treating Pediatric Obesity in Neurodevelopmental Disorders is a must-have resource for clinicians, scientist-practitioners, and related professionals as well as researchers, professors, and graduate students in clinical child and school psychology, public health, social work, pediatrics, occupational therapy, and nutrition.

Neurodevelopmental Disorders, from DSM-5(R) Selections, is a custom-published product crafted around a specific disorder cited in DSM-5. This selection provides a comprehensive overview of the process of diagnosing sleep-wake disorders while serving as a reference guide to assist in the diagnosis of individual patients. The disorder-specific resource is an invaluable addition to the DSM-5(R) collection and an important contribution to the mental health profession. This book contains the critical disorder-specific content from these four titles: - Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5(R)) - DSM-5(R) Clinical Cases- DSM-5(R) Self-Exam Questions- DSM-5(R) Guidebook

A practical guide to adaptive behaviors across a range of neurodevelopmental disorders Adaptive behavior assessment measures independent living skills, including communication, social skills, personal care, and practical work skills. For individuals with intellectual disabilities, evaluation of these skills is a critical tool for measuring eligibility and can identify specific skills that must be learned before effective educational interventions can be implemented. Essentials of Adaptive Behavior Assessment of Neurodevelopmental Disorders describes the role of adaptive behavior in assessment and treatment, and provides clear guidance for measurement. Case samples provide real-world illustration of behaviors and assessment, and systematic comparison of various measures are presented and explained to better inform planning. Individual chapters outline specific adaptive behaviors across a range of neurodevelopmental disorders, giving clinicians, practitioners, students, and researchers a better understanding of diagnostic differentials and how to place independent skill programming in treatment and intervention. Plan intervention and treatment based on accessible measurement guidelines across a range of disorders Gain a deeper understanding of adaptive functioning specific to ADHD, autism spectrum disorders, disruptive behavior disorders, and genetic disorders Compare and contrast current measures to evaluate their strengths, weaknesses, and areas of overlap Quickly locate essential information with Rapid Reference and Caution boxes For individuals with neurodevelopmental disorders, adaptive behaviors are the keys to independence; without them, these individuals will perpetually struggle with achieving optimum independence without the basic skills needed to function at home, in school, and in the community. Assessment allows these skills to be factored in to treatment and intervention planning, and can help improve the outcomes of other intervention methods. Essentials of Adaptive Behavior Assessment of Neurodevelopmental Disorders clarifies the assessment of these important behaviors, helping clinicians make more informed decisions around diagnosis, education, and treatment planning.

​This book explores how music can improve skills that are impaired in some neurodevelopmental disorders, including ADHD (attention deficit hyperactivity disorder), autism, and Rett syndrome. Rehabilitation interventions based on the use of music, termed "music therapy," are relatively widespread, but not all are supported by empirical evidence. This book offers readers an updated and scientifically grounded perspective on this theory and argues that music can be effective in promoting the acquisition of some basic mental abilities. Chapters present some of the latest research and data on how musical activities can lead children affected by neurodevelopmental disorders to improve those skills, including examples of training programs and exercises. The book will be a valuable resource for therapists, rehabilitators, psychologists, educators, musicians, researchers, as well as anyone interested in exploring the potential in music for human growth. Alessandro Antonietti is Professor of Applied Cognitive Psychology at the Catholic University of the Sacred Heart, Italy. There he is the head of the Department of Psychology and coordinates the Cognitive Psychology Lab. His research interests lie in the applications of cognitive issues in the field of instruction and rehabilitation. Barbara Colombo is Associate Professor of Cognitive Neuroscience at Champlain College, USA, where she is Head of the Neuroscience Lab. Her most recent research has been focused on exploring the role of individual differences in modulating cognitive and emotional behaviours. Braelyn R. DeRocher is affiliated with the Neuroscience Lab at Champlain College, USA. His research interests are related to empathy, aggression, and personal empowerment, focusing on at-risk youth.

Neurodevelopmental Disorders: Diagnosis and Treatment summarizes a vast body of literature concerning diagnosis and treatment for a variety of neurodevelopmental disorders, including both common and rare conditions. Throughout the book, Dr. Hagerman synthesizes treatment information for many disciplines that work together to provide multi-modality intervention. Psychopharmacological information and recommendations as well as the latest knowledge regarding genetic and diagnostic aspects of each disorder are explained in detail. And all chapters have one or more case studies to model the treatment recommendations, which are enhanced by extensive appendices reviewing educational programs, computer software, and supplementary reading. In addition, a detailed resource list of organizations, educational materials, and internet connections accompanies each chapter. This book not only integrates but also advances our knowledge of treatment, which is of prime importance for clinicians, therapists, educators, and parents.

Nowadays, it is widely accepted that there is no single influence (be it nature or nurture) on cognitive development. Cognitive abilities emerge as a result of interactions between gene expression, cortical and subcortical brain networks, and environmental influences. In recent years, our study of neurodevelopmental disorders has provided much valuable information on how genes, brain development, behaviour, and environment interact to influence development from infancy to adulthood. This is the first book to present evidence on development across the lifespan across these multiple levels of description (genetic, brain, cognitive, environmental). In the book, the authors have chosen a well-defined disorder, Williams syndrome (WS), to explore the impact of genes, brain development, behaviour, as well as the individual's environment on development. WS is used as a model disorder to demonstrate the authors approach to understanding development, whilst being presented in comparison to other neurodevelopmental disorders - Autism, Developmental Dyscalculia, Down syndrome, Dyslexia, Fragile X syndrome, Prader-Willi syndrome, Specific Language Impairment, Turner syndrome - to illustrate differences in development across neurodevelopmental disorders. Williams syndrome is particularly informative for exploring development: Firstly, it has been extensively researched at multiple levels: genes, brain, cognition and behaviour, as well as in terms of the difficulties of daily living and social interaction. Secondly, it has been studied across the lifespan, with many studies on infants and toddlers with WS as well as a large number on children, adolescents and adults. The authors also explore a number of domain-general and domain-specific processes in the verbal, non-verbal and social domains, across numerous neurodevelopmental disorders. This illustrates, among other factors, the importance of developmental timing, i.e. that the development of a cognitive skill at a specific timepoint can impact on subsequent development within that domain, but also across domains. In addition, the authors discuss the value of investigating basic-level abilities from as close to the infant start-state as possible, presenting evidence of where cross-syndrome comparisons have shed light on the cascading impacts of subtle similarities and discrepancies in early delay or deviance, on subsequent development. Designed such that readers with an interest in any neurodevelopmental disorder can gain insight into the intricate dynamics of cognitive development, the book covers both theoretical issues and those of clinical relevance. It will be an invaluable reference for any researcher, clinician, student as well as interested parents or teachers wishing to learn about neurodevelopmental disorders from a developmental framework.

Disorder-assistive and neurotechnological devices are experiencing a boom in the global market. Mounting evidence suggests that approaches based on several different domains should move towards the goal of early diagnosis of individuals affected by neurodevelopmental disorders. Using an interdisciplinary and collaborative approach in diagnosis and support can resolve many hurdles such as lack of awareness, transport, and financial burdens by being made available to individuals at the onset of symptoms. Interdisciplinary Approaches to Altering Neurodevelopmental Disorders is a pivotal reference source that explores neurodevelopmental disorders and a diverse array of diagnostic tools and therapies assisted by neurotechnological devices. While covering a wide range of topics including individual-centered design, artificial intelligence, and multifaceted therapies, this book is ideally designed for neuroscientists, medical practitioners, clinical psychologists, special educators, counselors, therapists, researchers, academicians, and students.