Neurobiology of Depression

Neurobiology of Depression
Author: Joao Luciano de Quevedo,Andre Ferrer Carvalho,Carlos A. Zarate
Publsiher: Academic Press
Total Pages: 471
Release: 2019-01-03
ISBN 10: 0128133341
ISBN 13: 9780128133347
Language: EN, FR, DE, ES & NL

Neurobiology of Depression Book Review:

Neurobiology of Depression: Road to Novel Therapeutics synthesizes the basic neurobiology of major depressive disorder with discussions on the most recent advances in research, including the interacting pathways implicated in the pathophysiology of MDD, omics technologies, genetic approaches, and the development of novel optogenetic approaches that are changing research perspectives and revolutionizing research into depression. These basic foundational understandings on the neurobiology underlying the disorder, along with a comprehensive summary of the most recent advances in research are combined in this book to aid advanced students and researchers in their understanding of MDD. Depression is one of the most common mental-health disorders caused by a variety of genetic, biological, environmental and psychological factors. Major depressive disorder (MDD) is typically treated with first-line antidepressant agents that primarily target monoamine neurotransmission. However, only approximately one-third of patients with MDD achieve remission following a trial with such an antidepressant. Furthermore, MDD is a heterogeneous phenotype, and new frameworks, such as the NIMH Research Domain Criteria (RDoC) may provide a more accurate, biologically based comprehension of the symptomatic heterogeneity of this devastating illness. Aids readers in understanding major depressive disorder in the context of NIMH Research Domain Criteria (RDoC) recommendations Covers a range of existing and potential pharmacologic and non-pharmacologic treatment options, from lifestyle adjustments, to antidepressants and novel therapeutics Synthesizes discussions on the cellular and molecular mechanisms underlying symptoms with the clinical aspects of depression

Neurobiology of Depression

Neurobiology of Depression
Author: Francisco Lopez-Munoz,Cecilio Alamo
Publsiher: CRC Press
Total Pages: 526
Release: 2011-09-09
ISBN 10: 143983850X
ISBN 13: 9781439838501
Language: EN, FR, DE, ES & NL

Neurobiology of Depression Book Review:

Major depressive disorders have recently been associated with impairments in signaling pathways that regulate neuroplasticity and cell survival. Agents designed to directly target molecules in these pathways hold promise as new therapeutics for depression. With the collaboration of the most prestigious international specialists in biochemistry, molecular biology, genomics, psychiatry, psychology, and pharmacology, Neurobiology of Depression discusses the nature of the central nervous system circuits responsible for the modifications of neuronal functioning that lead to depression. The book begins by discussing animal, neurophysiological, and neuropsychological models of depression as well as neural foundations. It explores genetic factors that contribute to depression and describes the effect of monoaminergic systems in the central nervous system. Next, the book profiles the rise of psychopharmacology in the treatment of depression and the research into serotonin and monoamine reuptake inhibitors. It examines the role of the glutamatergic, endocannabinoid, and opioid systems in the pathophysiology of mood disorders, as well as the effect of biological rhythms on the human body. Later chapters review the role of CRF-related ligands, CRF receptors, HPA axis activity, and glucocorticoid receptors in the regulation of the stress response and depression. They also describe cytokine modulation of molecular mechanisms. They examine the role of neuropeptide Y, nitric oxide, beta-arrestins, BDNF, and phosphodiesterases, and discuss the use of tachykinin antagonists in treatment. Finally, they analyze the neurobiological basis for the development of new antidepressant agents. Exploring myriad aspects of a disease that plagues a large percentage of the population worldwide, this volume captures the state of the science of this debilitating disorder, facilitating further research and discovery.

Systems Neuroscience in Depression

Systems Neuroscience in Depression
Author: Thomas Frodl
Publsiher: Academic Press
Total Pages: 420
Release: 2016-09-01
ISBN 10: 0128026286
ISBN 13: 9780128026281
Language: EN, FR, DE, ES & NL

Systems Neuroscience in Depression Book Review:

Systems Neuroscience in Depression provides a comprehensive overview of the normal and depressed brain processes as studied from a systems neuroscience perspective. Systems neuroscience uses a wide variety of approaches to study how networks of neurons form the bases of higher brain function. A broad overview is discussed starting with a background from neurodevelopment and neural understanding as well as novel treatment approaches for depression. This book covers basic developmental aspects and depressive psychopathology, as well as the basic scientific background from animal models and experimental research. Current advances in systems neuroscience are highlighted in studies from child and adolescent psychiatry. Integrated approaches are presented with regards to genetics, neuroimaging and neuroinflammation as well as neuroendocrinology. The field of systems and network neuroscience is evolving rapidly and this book provides a greatly needed resource for researchers and practitioners in systems neuroscience and psychiatry. Knowledge covering the whole life span from early to later life Comprehensively written chapters developing from molecules via epigenetics and neural circuits to clinical neuroscience Understanding the neurobiology of major depressive disorder Integrating stress and environmental factors with molecular underpinnings More than 25 illustrations and tables

The Neurobiological Basis of Suicide

The Neurobiological Basis of Suicide
Author: Yogesh Dwivedi
Publsiher: CRC Press
Total Pages: 482
Release: 2012-06-25
ISBN 10: 143983881X
ISBN 13: 9781439838815
Language: EN, FR, DE, ES & NL

The Neurobiological Basis of Suicide Book Review:

With recent studies using genetic, epigenetic, and other molecular and neurochemical approaches, a new era has begun in understanding pathophysiology of suicide. Emerging evidence suggests that neurobiological factors are not only critical in providing potential risk factors but also provide a promising approach to develop more effective treatment and prevention strategies. The Neurobiological Basis of Suicide discusses the most recent findings in suicide neurobiology. Psychological, psychosocial, and cultural factors are important in determining the risk factors for suicide; however, they offer weak prediction and can be of little clinical use. Interestingly, cognitive characteristics are different among depressed suicidal and depressed nonsuicidal subjects, and could be involved in the development of suicidal behavior. The characterization of the neurobiological basis of suicide is in delineating the risk factors associated with suicide. The Neurobiological Basis of Suicide focuses on how and why these neurobiological factors are crucial in the pathogenic mechanisms of suicidal behavior and how these findings can be transformed into potential therapeutic applications.

Ketamine for Treatment Resistant Depression

Ketamine for Treatment Resistant Depression
Author: Gustavo H. Vazquez,Carlos A. Zarate,Elisa Brietzke
Publsiher: Academic Press
Total Pages: 168
Release: 2020-10-01
ISBN 10: 0128210346
ISBN 13: 9780128210345
Language: EN, FR, DE, ES & NL

Ketamine for Treatment Resistant Depression Book Review:

Ketamine for Treatment-Resistant Depression: Neurobiology and Applications provides a simple, evidence-based overview for neuropsychiatrists and translational researchers on this medication, its mechanisms of actions, eligibility of patients for treatment, and the preparation and implementation of ketamine clinics. Provides efficacy research on ketamine as a treatment for depression Identifies best practices for clinical use, both long-term and acute Discusses the molecular mechanisms and neurobiology of action

Rapid Acting Antidepressants

Rapid Acting Antidepressants
Author: Anonim
Publsiher: Academic Press
Total Pages: 402
Release: 2020-06-29
ISBN 10: 0128201908
ISBN 13: 9780128201909
Language: EN, FR, DE, ES & NL

Rapid Acting Antidepressants Book Review:

The Advances in Pharmacology series presents a variety of chapters from the best authors in the field. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Major Depressive Disorder

Major Depressive Disorder
Author: Yong-Ku Kim
Publsiher: BoD – Books on Demand
Total Pages: 156
Release: 2015-06-11
ISBN 10: 9535121294
ISBN 13: 9789535121299
Language: EN, FR, DE, ES & NL

Major Depressive Disorder Book Review:

Major depressive disorder (MDD) is a complex and heterogeneous disorder, phenotypically and biologically. MDD may be caused by complex interaction between genes and environment in susceptible individuals. Thus, a combination of certain genetic polymorphism, environmental stress, and personal susceptibility ultimately may induce MDD. Gene-environment interactions in the pathophysiology of MDD lead to advancement in personalized medicine by means of genotyping for inter-individual variability in drug action and metabolism. Gene-environment interactions may explain why some subjects become depressed while others remain unaffected. The aim of this book is to describe current knowledge of MDD from the point of view of neurobiology, molecular genetics and cognition. The authors address a deep understanding of cognitive and neurobiological mechanisms involved in MDD.

Behavioral Neurobiology of Depression and Its Treatment

Behavioral Neurobiology of Depression and Its Treatment
Author: Philip J. Cowen,Trevor Sharp,Jennifer Y . F. Lau
Publsiher: Springer Science & Business Media
Total Pages: 344
Release: 2014-04-24
ISBN 10: 3642354254
ISBN 13: 9783642354250
Language: EN, FR, DE, ES & NL

Behavioral Neurobiology of Depression and Its Treatment Book Review:

The book highlights important new research using current state-of-the-art approaches by prominent researchers in the field of depression. A broad range of topics is covered, beginning with a description of the phenotypic features of clinical depression, followed by chapters on the cellular and molecular basis, functional neuroimaging correlates and information-processing accounts. Finally, existing and novel treatment approaches are covered. In this way the volume brings together the key disciplines involved in the neurobiological understanding of depression to provide an update of the field and outlook to the future. Together, the volume chapters provide focused and critical reviews that span a broad range of topics suitable for both students and established investigators interested in the present state of depression research.

Neurobiology of Mood Disorders

Neurobiology of Mood Disorders
Author: Bruno P. Guiard,Eliyahu Dremencov
Publsiher: Bentham Science Publishers
Total Pages: 300
Release: 2014-02-27
ISBN 10: 1608054675
ISBN 13: 9781608054671
Language: EN, FR, DE, ES & NL

Neurobiology of Mood Disorders Book Review:

This monograph is a collection of selected articles on the subject of mood disorders such as depression and schizophrenia. It is divided into 3 sections: 1) Research methods in psychopharmacology - which highlights some established experimental techniques to study mood disorders in human and relevant animal models, 2) Pathophysiology of mood disorders – which explains the physiological and pharmacological mechanisms responsible for mood disorders and 3) New strategies for the treatment of mood disorders – a concluding section that provides recent examples on the beneficial effects of pharmacological and non-pharmacological interventions in the relief of mood disorders. The e-book serves as a primer for graduate students and researchers interested in the physiology and treatment of affective psychological disorders.

Neurobiology of Mental Illness

Neurobiology of Mental Illness
Author: Dennis S. Charney,Eric J. Nestler,Pamela Sklar,Joseph D. Buxbaum
Publsiher: Oxford University Press
Total Pages: 1222
Release: 2013-07-04
ISBN 10: 0199934959
ISBN 13: 9780199934959
Language: EN, FR, DE, ES & NL

Neurobiology of Mental Illness Book Review:

Our understanding of the neurobiological basis of psychiatric disease has accelerated in the past five years. The fourth edition of Neurobiology of Mental Illness has been completely revamped given these advances and discoveries on the neurobiologic foundations of psychiatry. Like its predecessors the book begins with an overview of the basic science. The emerging technologies in Section 2 have been extensively redone to match the progress in the field including new chapters on the applications of stem cells, optogenetics, and image guided stimulation to our understanding and treatment of psychiatric disorders. Sections' 3 through 8 pertain to the major psychiatric syndromes-the psychoses, mood disorders, anxiety disorders, substance use disorders, dementias, and disorders of childhood-onset. Each of these sections includes our knowledge of their etiology, pathophysiology, and treatment. The final section discusses special topic areas including the neurobiology of sleep, resilience, social attachment, aggression, personality disorders and eating disorders. In all, there are 32 new chapters in this volume including unique insights on DSM-5, the Research Domain Criteria (RDoC) from NIMH, and a perspective on the continuing challenges of diagnosis given what we know of the brain and the mechanisms pertaining to mental illness. This book provides information from numerous levels of analysis including molecular biology and genetics, cellular physiology, neuroanatomy, neuropharmacology, epidemiology, and behavior. In doing so it translates information from the basic laboratory to the clinical laboratory and finally to clinical treatment. No other book distills the basic science and underpinnings of mental disorders and explains the clinical significance to the scope and breadth of this classic text. The result is an excellent and cutting-edge resource for psychiatric residents, psychiatric researchers and doctoral students in neurochemistry and the neurosciences.

Bipolar Depression Molecular Neurobiology Clinical Diagnosis and Pharmacotherapy

Bipolar Depression  Molecular Neurobiology  Clinical Diagnosis and Pharmacotherapy
Author: Carlos A. Zarate Jr.,Husseini K. Manji
Publsiher: Springer Science & Business Media
Total Pages: 279
Release: 2009-04-16
ISBN 10: 3764385677
ISBN 13: 9783764385675
Language: EN, FR, DE, ES & NL

Bipolar Depression Molecular Neurobiology Clinical Diagnosis and Pharmacotherapy Book Review:

Although our knowledge of mood disorders is expanding, comparatively little is known about bipolar depression in particular. This book offers the most up-to-date information about the diagnosis, treatment, and research surrounding bipolar depression. Early chapters provide diagnostic information and review the course, outcome and genetics of this heritable condition. The book gives a thorough and unique overview of the neurobiology of the disorder, including neuroimaging work. Several chapters delineate the treatment of bipolar depression in special populations such as children and pregnant women. Furthermore, the particular issues of suicide, focusing on the need for assessment during both acute and maintenance treatment, are addressed. Finally, acute and long-term treatment strategies for bipolar depression are discussed, including both traditional and novel therapeutics, as well as non-pharmacological treatments. This volume offers researchers and clinicians key insights into this devastating disorder.

Depression in Medical Illness

Depression in Medical Illness
Author: Arthur J. Barsky,David A. Silbersweig
Publsiher: McGraw Hill Professional
Total Pages: 400
Release: 2017-04-05
ISBN 10: 0071819096
ISBN 13: 9780071819091
Language: EN, FR, DE, ES & NL

Depression in Medical Illness Book Review:

An authoritative guide to understanding and treating depression in the medically ill Depression in Medical Illness is based on the fact that depression and medical illness are inextricably bound together and must be viewed through a single lens in order to truly understand, diagnose, and treat them. Throughout the book, the authors emphasize not simply a critical distillation and balanced summary of the available empirical data, but equally important, an active synthesis, formulation, and analysis of that evidence.This informs a contemporary biomedical understanding, as well as diagnostic and therapeutic approaches. All of the chapters are authored by members of the Department of Psychiatry at the world-renowned Brigham and Women’s Hospital. In chapters devoted to specific medical disorders, psychiatrists with particular expertise in those areas have been joined by other eminent Brigham medical and surgical specialists or subspecialists. This makes these chapters valuable not just to psychiatrists and other mental health professionals, but to a wide range of medical specialists as well. Logically Organized Into Five Sections: Core Concepts – provides a conceptual and intellectual framework for understanding depressive illness in the context of medical illness Assessment and Treatment of Depression in Medically Ill Patients – discusses the general principles of depression diagnosis and treatment Depression in Medical Illness – Assesses what we know about depression when it is comorbid with the full range of major medical disorders Special Populations and Settings – Is devoted to special patient populations and the importance of the settings in which care is delivered New Directions – A fascinating glimpse into the future of the care of medically ill patients who are depressed

The Upward Spiral

The Upward Spiral
Author: Alex Korb
Publsiher: New Harbinger Publications
Total Pages: 232
Release: 2015-03-01
ISBN 10: 1626251223
ISBN 13: 9781626251229
Language: EN, FR, DE, ES & NL

The Upward Spiral Book Review:

Depression can feel like a downward spiral, pulling you into a vortex of sadness, fatigue, and apathy. In The Upward Spiral, neuroscientist Alex Korb demystifies the intricate brain processes that cause depression and offers a practical and effective approach to getting better. Based on the latest research in neuroscience, this book provides dozens of straightforward tips you can do every day to rewire your brain and create an upward spiral towards a happier, healthier life. Whether you suffer from depression or just want a better understanding of the brain, this book offers an engaging and informative look at the neuroscience behind our emotions, thoughts, and actions. The truth is that there isn’t one big solution to depression, but there are numerous simple steps you can take to alter brain activity and chemistry. Some are as easy as relaxing certain muscles to reduce anxiety, or getting more sunlight to improve your mood. Small steps in the right direction can have profound effects—giving you the power to become your best self as you literally reshape your brain, one small change at a time.

Neurobiology of Brain Disorders

Neurobiology of Brain Disorders
Author: Michael J. Zigmond,Joseph T. Coyle,Lewis P. Rowland
Publsiher: Elsevier
Total Pages: 824
Release: 2014-12-03
ISBN 10: 0123982804
ISBN 13: 9780123982803
Language: EN, FR, DE, ES & NL

Neurobiology of Brain Disorders Book Review:

Neurobiology of Brain Disorders is the first book directed primarily at basic scientists to offer a comprehensive overview of neurological and neuropsychiatric disease. This book links basic, translational, and clinical research, covering the genetic, developmental, molecular, and cellular mechanisms underlying all major categories of brain disorders. It offers students, postdoctoral fellows, and researchers in the diverse fields of neuroscience, neurobiology, neurology, and psychiatry the tools they need to obtain a basic background in the major neurological and psychiatric diseases, and to discern connections between basic research and these relevant clinical conditions. This book addresses developmental, autoimmune, central, and peripheral neurodegeneration; infectious diseases; and diseases of higher function. The final chapters deal with broader issues, including some of the ethical concerns raised by neuroscience and a discussion of health disparities. Included in each chapter is coverage of the clinical condition, diagnosis, treatment, underlying mechanisms, relevant basic and translational research, and key unanswered questions. Written and edited by a diverse team of international experts, Neurobiology of Brain Disorders is essential reading for anyone wishing to explore the basic science underlying neurological and neuropsychiatric diseases. Links basic, translational, and clinical research on disorders of the nervous system, creating a format for study that will accelerate disease prevention and treatment Covers a vast array of neurological disorders, including ADHD, Down syndrome, autism, muscular dystrophy, diabetes, TBI, Parkinson, Huntington, Alzheimer, OCD, PTSD, schizophrenia, depression, and pain Illustrated in full color Each chapter provides in-text summary points, special feature boxes, and research questions Provides an up-to-date synthesis of primary source material

Stress the Brain and Depression

Stress  the Brain and Depression
Author: H. M. van Praag,E. R. de Kloet,J. van Os
Publsiher: Cambridge University Press
Total Pages: 283
Release: 2004-05-20
ISBN 10: 9781139451246
ISBN 13: 1139451243
Language: EN, FR, DE, ES & NL

Stress the Brain and Depression Book Review:

Can traumatic life events cause depression? Studies generally point to a connection between adverse life events and depression. However, establishing a causal rather than associative connection, the key concern of this book, is more problematic. What neurobiological changes may be induced by stress and depression, and to what extent do these changes correspond? The authors structure their examination around three major themes: the pathophysiological role of stress in depression; whether or not a subtype of depression exists that is particularly stress-inducible; and, finally, how best to diagnose and treat depression in relation to its biological underpinnings.

Neurobiology of Psychiatric Disorders

Neurobiology of Psychiatric Disorders
Author: Thomas E. Schlaepfer,Charles B. Nemeroff
Publsiher: Elsevier
Total Pages: 760
Release: 2012
ISBN 10: 0444520023
ISBN 13: 9780444520029
Language: EN, FR, DE, ES & NL

Neurobiology of Psychiatric Disorders Book Review:

This new volume in the Handbook of Clinical Neurology presents a comprehensive review of the fundamental science and clinical treatment of psychiatric disorders. Advances in neuroscience have allowed for dramatic advances in the understanding of psychiatric disorders and treatment. Brain disorders, such as depression and schizophrenia, are the leading cause of disability worldwide. It is estimated that over 25% of the adult population in North America are diagnosed yearly with at least one mental disorder and similar results hold for Europe. Now that neurology and psychiatry agree that all mental disorders are in fact, "brain diseases," this volume provides a foundational introduction to the science defining these disorders and details best practices for psychiatric treatment. Provides a comprehensive review of the scientific foundations of psychiatric disorders and psychiatric treatment Includes detailed results from genetics, molecular biology, brain imaging, and neuropathological, immunological, epidemiological, metabolic, therapeutic and historical aspects of the major psychiatric disorders A "must have" reference and resource for neuroscientists, neurologists, psychiatrists, and clinical psychologists as well as all research scientists investigating disorders of the brain

Routledge Handbook of Physical Activity and Mental Health

Routledge Handbook of Physical Activity and Mental Health
Author: Panteleimon Ekkekakis
Publsiher: Routledge
Total Pages: 600
Release: 2013-08-21
ISBN 10: 1136477799
ISBN 13: 9781136477799
Language: EN, FR, DE, ES & NL

Routledge Handbook of Physical Activity and Mental Health Book Review:

A growing body of evidence shows that physical activity can be a cost-effective and safe intervention for the prevention and treatment of a wide range of mental health problems. As researchers and clinicians around the world look for evidence-supported alternatives and complements to established forms of therapy (medication and psychotherapy), interest in physical activity mounts. The Routledge Handbook of Physical Activity and Mental Health offers the most comprehensive review of the research evidence on the effects of physical activity on multiple facets of mental health. Written by a team of world-leading international experts, the book covers ten thematic areas: physical activity and the ‘feel good’ effect anxiety disorders depression and mood disorders self-perceptions and self-evaluations cognitive function across the lifespan psychosocial stress pain energy and fatigue addictions quality of life in special populations. This volume presents a balanced assessment of the research evidence, highlights important directions for future work, and draws clear links between theory, research, and clinical practice. As the most complete and authoritative resource on the topic of physical activity and mental health, this is essential reading for researchers, students and practitioners in a wide range of fields, including clinical and health psychology, psychiatry, neuroscience, behavioural and preventive medicine, gerontology, nursing, public health and primary care.

Melancholia A Disorder of Movement and Mood

Melancholia  A Disorder of Movement and Mood
Author: Gordon Parker,Dusan Hadzi-Pavlovic,Kerrie Eyers
Publsiher: Cambridge University Press
Total Pages: 342
Release: 1996-03-29
ISBN 10: 9780521472753
ISBN 13: 052147275X
Language: EN, FR, DE, ES & NL

Melancholia A Disorder of Movement and Mood Book Review:

Describes the development of a new approach to the diagnosis and pathogenesis of melancholic depression.

The Neuroscience of Suicidal Behavior

The Neuroscience of Suicidal Behavior
Author: Kees van Heeringen
Publsiher: Cambridge University Press
Total Pages: 286
Release: 2018-08-23
ISBN 10: 1107148944
ISBN 13: 9781107148949
Language: EN, FR, DE, ES & NL

The Neuroscience of Suicidal Behavior Book Review:

Contrary to common belief, suicide is preventable and insights from neuroscientific research show how.

The Oxford Handbook of Mood Disorders

The Oxford Handbook of Mood Disorders
Author: Robert J. DeRubeis,Daniel R. Strunk
Publsiher: Oxford University Press
Total Pages: 514
Release: 2017
ISBN 10: 0199973962
ISBN 13: 9780199973965
Language: EN, FR, DE, ES & NL

The Oxford Handbook of Mood Disorders Book Review:

The most comprehensive volume of its kind, The Oxford Handbook of Mood Disorders provides detailed coverage of the characterization, understanding, and treatment of mood disorders. Chapters are written by the world's leading experts in their respective areas. The Handbook provides coverage of unipolar depression, bipolar disorder, and variants of these disorders. Current approaches to classifying the mood disorders are reviewed and contemporary controversies are placed in historical context. Chapter authors offer a variety of approaches to understanding the heterogeneity of the experiences of those who meet criteria for mood disorders, both within and across cultures. The role of genetic and environmental risk factors as well as premorbid personality and cognitive processes in the development of mood pathology are detailed. Interpersonal, neurobiological, and psychological factors also receive detailed consideration. The volume reviews mood disorders in special populations (e.g., postpartum and seasonal mood disorders) as well as common comorbidities (e.g., anxiety, substance use disorders). Somatic and psychosocial treatment approaches receive in-depth coverage with chapters that describe and review empirical evidence regarding each of the most influential treatment approaches. The depth and breadth offered by this Handbook make it an invaluable resource for clinicians and researchers, as well as scholars and students.