Neural Stem Cells and Adult Neurogenesis

Neural Stem Cells and Adult Neurogenesis
Author: Arie S. Mobley
Publsiher: Academic Press
Total Pages: 375
Release: 2019-03-15
ISBN 10: 0128110147
ISBN 13: 9780128110140
Language: EN, FR, DE, ES & NL

Neural Stem Cells and Adult Neurogenesis Book Review:

Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons' contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format. Provides a basic understanding of what a stem cell is, the different types, and their potential in health and research Details adult neurogenesis and its role in behavior, stroke and disease Includes walkthrough and technology boxes that illustrate experimental concepts, new approaches and techniques

Neural Stem Cells and Adult Neurogenesis

Neural Stem Cells and Adult Neurogenesis
Author: Arie S. Mobley
Publsiher: Academic Press
Total Pages: 241
Release: 2019-02-28
ISBN 10: 0128110155
ISBN 13: 9780128110157
Language: EN, FR, DE, ES & NL

Neural Stem Cells and Adult Neurogenesis Book Review:

Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons’ contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format. Provides a basic understanding of what a stem cell is, the different types, and their potential in health and research Details adult neurogenesis and its role in behavior, stroke and disease Includes walkthrough and technology boxes that illustrate experimental concepts, new approaches and techniques

Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine
Author: Philippe Taupin
Publsiher: Nova Publishers
Total Pages: 164
Release: 2008
ISBN 10: 9781604564723
ISBN 13: 1604564725
Language: EN, FR, DE, ES & NL

Stem Cells and Regenerative Medicine Book Review:

The subject of this book is stem cell research and regenerative medicine. Stem cells are undifferentiated cells that have the ability to differentiate into different lineages of the body. Stem cells carry tremendous potential for the treatment of a broad range of disease and injuries. Stem cells exist in embryonic, fetal, and adult tissues, including the adult central nervous system. This book aims at, in depth, the recent developments in stem cell research and regenerative medicine. Though this book encompasses all the fields of stem cell research and regenerative medicine, it emphasises adult neurogenesis and neural stem cell research and therapy.

Adult Neurogenesis

Adult Neurogenesis
Author: Gerd Kempermann
Publsiher: Oxford University Press, USA
Total Pages: 426
Release: 2006
ISBN 10: 9780195179712
ISBN 13: 0195179714
Language: EN, FR, DE, ES & NL

Adult Neurogenesis Book Review:

The discovery of adult neurogenesis and of stem cells in the brain has changed our view of the mature brain. Though we now know that the adult brain can make new neurons, it normally does so only in two privileged regions, the olfactory bulb and the hippocampus. Yet stem cells, which have the potential to produce new neurons, can be found throughout the adult brain. So why does the brain not make wider use of its potential for neurogenesis? And what is the function of new neurons and of neural stem cells in areas where they occur? After all, the brain regenerates poorly and many neurological and psychiatric disorders are chronic because cell replacement has not taken place. This is the first comprehensive, integrated account of one of the most exciting areas of neuroscience. It begins with the historical background and discusses theories of adult neurogenesis and neural stem cell biology in the context of learning and memory processes as well as structural plasticity. It describes in detail neurogenesis in the adult hippocampus and olfactory system and then surveys the regulatory, functional, and comparative aspects, concluding with a chapter on the provocative hypotheses that link failing adult neurogenesis with such diseases as temporal lobe epilepsy, major depression, brain tumors, and dementias. For graduate students, investigators, and clinicians in the neurosciences, developmental biology, and stem cell research, this book is a unique resource that sifts through the evidence for exciting scientific ideas and fosters a realistic view of the therapeutic possibilities for the use of stem cells in the adult brain.

Adult Neurogenesis and Neural Stem Cells in Mammals

Adult Neurogenesis and Neural Stem Cells in Mammals
Author: Philippe Taupin
Publsiher: Nova Publishers
Total Pages: 208
Release: 2006
ISBN 10: 9781594548567
ISBN 13: 1594548560
Language: EN, FR, DE, ES & NL

Adult Neurogenesis and Neural Stem Cells in Mammals Book Review:

This title contains a book and CD. The brain has a number of nerve cells estimated at a magnitude of 10 to 100 billion, and 1014 to 1015 synapses, and therefore is the most complex organ of the human body. During fetal development the foundations of the brain are laid as billions of neurons form appropriate connections and patterns. In the adult mammalian brain, most neurons are post-mitotic, and therefore at risk for irreversible damage. As we age, atrophy of the brain occurs. As brain weight declines the volume of the brain in the 8th decade is reduced by 6 per cent -10 per cent versus the third decade, and neuronal loss occurs, up to 10,000 to 100,000 neurons are lost per day, though this estimation is being revised downward with the advance of more sophisticated measurements.

Emerging Roles for Hippocampal Adult Neural Stem Cells in Memory

Emerging Roles for Hippocampal Adult Neural Stem Cells in Memory
Author: Aaron R. Friedman,Daniela Kaufer
Publsiher: Biota Publishing
Total Pages: 39
Release: 2013-12-01
ISBN 10: 1615044779
ISBN 13: 9781615044771
Language: EN, FR, DE, ES & NL

Emerging Roles for Hippocampal Adult Neural Stem Cells in Memory Book Review:

Approximately 50 years ago, newly generated neurons were discovered in the adult hippocampus of the rat brain. This discovery contradicted a key principle in mammalian developmental neurobiology—that all the neurons of the brain are made during early development—and led to intensive study to find out how new neurons are generated and how the process of neurogenesis is regulated. Since then, a unique population of adult neural stem cells has been identified, and many of the molecular pathways that control their self-renewal, proliferation, and cell fate have been elucidated. However, the presence of new neurons in the adult brain also poses intriguing functional questions that have, as yet, gone largely unanswered. Why is adult neurogenesis restricted to select brain regions? What functional benefit do these new cells confer? Indeed, the field of adult neurogenesis offers a unique opportunity to study naïve neurons as they mature, form connections with existing neural networks, and begin to participate in information processing. We review the basics of adult NSC biology and the maturation of newborn neurons. In particular, we focus on new neurons in the hippocampus, and how they contribute to function in this key memory-forming structure of the brain.

Generation of Neurons and Their Integration in Pre Existing Circuits in the Postnatal Brain Signalling in Physiological and Regenerative Contexts

Generation of Neurons and Their Integration in Pre Existing Circuits in the Postnatal Brain  Signalling in Physiological and Regenerative Contexts
Author: Helena Mira,Aixa Victoria Morales,Ruth Diez Del Corral
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-09-03
ISBN 10: 2889639886
ISBN 13: 9782889639885
Language: EN, FR, DE, ES & NL

Generation of Neurons and Their Integration in Pre Existing Circuits in the Postnatal Brain Signalling in Physiological and Regenerative Contexts Book Review:

Neural Stem Cells

Neural Stem Cells
Author: Luca Bonfanti
Publsiher: BoD – Books on Demand
Total Pages: 430
Release: 2013-04-24
ISBN 10: 9535110691
ISBN 13: 9789535110699
Language: EN, FR, DE, ES & NL

Neural Stem Cells Book Review:

Twenty years after the discovery of neural stem cells, the question whether the central nervous system can be considered among regenerative tissues is still open. On one side, deep characterization of neural stem and progenitor cells, their niches, and their progeny in brain neurogenic sites overtly showed that new neurons can be generated in the brain of adult mammals, including humans. On the other side, many problems arise when stem cells encounter the mature brain parenchyma, still hampering the development of efficacious therapeutic approaches with endogenous or exogenously-delivered neural stem cells. This book tries to make the point on these extremely promising, yet unresolved, issues.

Neural Stem Cells and Therapy

Neural Stem Cells and Therapy
Author: Tao Sun
Publsiher: BoD – Books on Demand
Total Pages: 454
Release: 2012-02-15
ISBN 10: 9533079584
ISBN 13: 9789533079585
Language: EN, FR, DE, ES & NL

Neural Stem Cells and Therapy Book Review:

This book is a collective work of international experts in the neural stem cell field. The book incorporates the characterization of embryonic and adult neural stem cells in both invertebrates and vertebrates. It highlights the history and the most advanced discoveries in neural stem cells, and summarizes the mechanisms of neural stem cell development. In particular, this book provides strategies and discusses the challenges of utilizing neural stem cells for therapy of neurological disorders and brain and spinal cord injuries. It is suitable for general readers, students, doctors and researchers who are interested in understanding the principles of and new discoveries in neural stem cells and therapy.

Adult Neurogenesis in the Hippocampus

Adult Neurogenesis in the Hippocampus
Author: Juan J. Canales
Publsiher: Academic Press
Total Pages: 298
Release: 2016-05-23
ISBN 10: 0128019921
ISBN 13: 9780128019924
Language: EN, FR, DE, ES & NL

Adult Neurogenesis in the Hippocampus Book Review:

Neurogenesis in the adult brain has emerged as one of the most dynamic and rapidly moving fields in modern neuroscience research. The implications of adult neurogenesis for health and well-being are wide-ranging, with findings in this area having distinct relevance for treatment and rehabilitation in neurology and psychopathology. Adult Neurogenesis in the Hippocampus addresses these implications by providing an up-to-date account on how neurogenesis in the adult hippocampus contributes to critical psychological and physiological processes, such as learning and memory, and how it is modified by life experiences, such as aging, environmental enrichment, exercise, and dieting. The book also provides the most current reviews of how adult hippocampal neurogenesis influences the pathogenesis of mood disorders, addiction, and key neurological disorders. This book is the ideal resource for researchers and advanced graduates seeking focused knowledge on the role of adult neurogenesis in brain health and disease. Provides a unique overview of how adult hippocampal neurogenesis contributes to adaptive processes, brain psychopathology, and disease Includes state-of-the-art reviews by leading world experts in adult neurogenesis

Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine
Author: Philippe Taupin
Publsiher: Nova Biomedical Books
Total Pages: 164
Release: 2008
ISBN 10: 9781616685782
ISBN 13: 1616685786
Language: EN, FR, DE, ES & NL

Stem Cells and Regenerative Medicine Book Review:

Neural Stem Cells in Health and Disease

Neural Stem Cells in Health and Disease
Author: Ashok K Shetty
Publsiher: World Scientific Publishing Company
Total Pages: 572
Release: 2015-08-28
ISBN 10: 9814623199
ISBN 13: 9789814623193
Language: EN, FR, DE, ES & NL

Neural Stem Cells in Health and Disease Book Review:

This book is a comprehensive guide on neural stem cell behavior in health and disease. The book confers the altered behavior of endogenous neural stem cells in neurodegenerative disease conditions and the prospects of neural stem cell therapy for alleviating brain dysfunction in a variety of neurodegenerative disorders. Neural stem cell activity and neurogenesis in the adult brain is now confirmed in virtually all mammalian species including humans. Hence, a series of chapters in the first half of the book discusses the current knowledge on mechanisms of neural stem cell activity, the extent and functional significance of neurogenesis in the adult brain under normal, aged and disease environments, the susceptibility of neural stem cells and the plasticity of neurogenesis to alcohol, drugs of abuse and anesthetic agents, and advanced techniques that trigger neurogenesis in non-neurogenic regions. A second series of chapters in this book are focused on discussing the promise and efficacy of grafting of neural stem cells and/or other stem cells for treating neurological disorders such as Parkinson's disease, stroke, temporal lobe epilepsy, Alzheimer's disease and spinal cord injury. The final chapter confers on advances that are made in manufacturing a variety of neural cell types from human pluripotent stem cells that can be used as donor cells for cell transplantation.

The ventricular subventricular zone a source of oligodendrocytes in the adult brain

The ventricular subventricular zone  a source of oligodendrocytes in the adult brain
Author: Oscar Gonzalez-Perez,Jose Manuel Garcia-Verdugo,Adan Aguirre
Publsiher: Frontiers E-books
Total Pages: 135
Release: 2014-09-30
ISBN 10: 2889192687
ISBN 13: 9782889192687
Language: EN, FR, DE, ES & NL

The ventricular subventricular zone a source of oligodendrocytes in the adult brain Book Review:

Demyelinating diseases are characterized by an extensive loss of oligodendrocytes and myelin sheaths from axolemma, which commonly result in disability in young adults. To date, there is no effective treatment against these neurological disorders. In the adult brain, there are neural stem cells (NSCs) that reside within a niche denominated ventricular-subventricular zone (V-SVZ) in the lateral wall of the cerebral ventricles. NSCs give rise to neurons and oligodendrocytes that help preserve cellular homeostasis. Growing evidence indicates that V-SVZ progenitor cells may represent an endogenous source of oligodendrocytes that can be useful to treat demyelinating diseases. This e-Book “The ventricular-subventricular zone as a source of oligodendrocytes in the adult brain” collected the most recent evidence regarding the mechanisms that modulate the proliferation, migration, quiescence, cell-fate choices and survival of oligodendrocyte precursors generated in the V-SVZ. Herein, we compiled information about the role of Sonic hedgehog, NMDA receptors, ErbB proteins, hemopressin, erythropoietin, osmolarity and microglia in the oligodendrocyte production. Some chapters also describe the role of oligodendrocyte precursors in the preservation of cellular homeostasis, aging and white matter repair. All these information is presented as novel research findings, short communications, and review articles, which were written by experts in the field of oligodendrocyte generation, myelin production and white matter re-myelination.

Neurogenesis in the Adult Brain I

Neurogenesis in the Adult Brain I
Author: Tatsunori Seki,Kazunobu Sawamoto,Jack M. Parent,Arturo Alvarez-Buylla
Publsiher: Springer Science & Business Media
Total Pages: 413
Release: 2011-06-15
ISBN 10: 9784431539339
ISBN 13: 4431539336
Language: EN, FR, DE, ES & NL

Neurogenesis in the Adult Brain I Book Review:

The discovery of adult neurogenesis caused a paradigm shift in the neurosciences. For more than 100 years, it was believed that adult neurons do not regenerate. Joseph Altman and Fernando Nottebohm found proof to the contrary and changed the course of history. Their research, included here, provides the foundations of the field. Today, adult neurogenesis is a rapidly expanding discipline applicable to the study of brain development and diseases, learning and memory, aging, and neuropsychiatric disorders. With multiple authors, the 27 chapters of this book contain the latest work in two volumes. The first presents the basic biology of adult neurogenesis in non-mammalian vertebrates and in the mammalian hippocampus and olfactory bulb, and the second discusses clinical implications and delves into adult neurogenesis and brain injury as well as neurodegenerative and neuropsychiatric pathologies. With details of the anatomy, physiology, and molecular biology of the two neurogenic brain regions, this book provides indispensable knowledge for many areas of neuroscience and for experimental and clinical applications of adult neurogenesis to brain therapy.

Adult neurogenesis twenty years later physiological function versus brain repair

Adult neurogenesis twenty years later  physiological function versus brain repair
Author: Paolo Peretto,Luca Bonfanti
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2015-05-01
ISBN 10: 2889194949
ISBN 13: 9782889194940
Language: EN, FR, DE, ES & NL

Adult neurogenesis twenty years later physiological function versus brain repair Book Review:

The discovery that mammalian brains contain neural stem cells which perform adult neurogenesis - the production and integration of new neurons into mature neural circuits - has provided a fully new vision of neural plasticity. On a theoretical basis, this achievement opened new perspectives for therapeutic approaches in restorative and regenerative neurology. Nevertheless, in spite of striking advancement concerning the molecular and cellular mechanisms which allow and regulate the neurogenic process, its exploitation in mammals for brain repair strategies remains unsolved. In non-mammalian vertebrates, adult neurogenesis also contributes to brain repair/regeneration. In mammals, neural stem cells do respond to pathological conditions in the so called "reactive neurogenesis", yet without substantial regenerative outcome. Why, even in the presence of stem cells in the brain, we lack an effective reparative outcome in terms of regenerative neurology, and which factors hamper the attainment of this goal? Essentially, what remains unanswered is the question whether (and how) physiological functions of adult neurogenesis in mammals can be exploited for brain repair purposes.

Neural Stem Cells in Development Adulthood and Disease

Neural Stem Cells in Development  Adulthood and Disease
Author: H. Georg Kuhn,Amelia J. Eisch
Publsiher: Springer
Total Pages: 202
Release: 2014-11-22
ISBN 10: 1493919083
ISBN 13: 9781493919086
Language: EN, FR, DE, ES & NL

Neural Stem Cells in Development Adulthood and Disease Book Review:

This comprehensive volume is the first to specifically target developing, adult and diseased neural stem cells. It explores recent advances in the understanding of neural stem cell biology along with strategies that use these cells to tackle neurological diseases and brain aging. Ten inclusive chapters discuss a wide range of topics including neurogenesis, neurodegeneration, demyelinating disease, mood regulation, and spinal cord regeneration, among others. Written by world-renowned scientists in the field, Neural Stem Cells in Development, Adulthood and Disease presents cutting-edge studies of interest to both established neurogenesis researchers and readers with general interests in nervous system science. It is an authoritative addition to the Stem Cell Biology and Regenerative Medicine series.

Stem Cells and Regenerative Medicine Embryonic and adult stem cells

Stem Cells and Regenerative Medicine  Embryonic and adult stem cells
Author: Philippe Taupin
Publsiher: Nova Publishers
Total Pages: 86
Release: 2008
ISBN 10: 9781604564730
ISBN 13: 1604564733
Language: EN, FR, DE, ES & NL

Stem Cells and Regenerative Medicine Embryonic and adult stem cells Book Review:

Annotation. The subject of this book is stem cell research and regenerative medicine. Stem cells are undifferentiated cells that have the ability to differentiate into different lineages of the body. Stem cells carry tremendous potential for the treatment of a broad range of disease and injuries. Stem cells exist in embryonic, foetal, and adult tissues, including the adult central nervous system. This book aims at, in depth, the recent developments in stem cell research and regenerative medicine. Though this book encompasses all the fields of stem cell research and regenerative medicine, it emphasises embryonic and adult stem cells.

Stem Cells and Regenerative Medicine

Stem Cells and Regenerative Medicine
Author: Anonim
Publsiher: Unknown
Total Pages: 164
Release: 2008
ISBN 10: 9781604564723
ISBN 13: 1604564725
Language: EN, FR, DE, ES & NL

Stem Cells and Regenerative Medicine Book Review:

Context Dependent Regulation of Neurogenesis Common Themes and Unique Features of the Neurogenic Process in Different Model Systems

Context Dependent Regulation of Neurogenesis  Common Themes and Unique Features of the Neurogenic Process in Different Model Systems
Author: Giuseppe Lupo,Michael Piper,Flavio Zolessi
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-05-25
ISBN 10: 2889668053
ISBN 13: 9782889668052
Language: EN, FR, DE, ES & NL

Context Dependent Regulation of Neurogenesis Common Themes and Unique Features of the Neurogenic Process in Different Model Systems Book Review:

Adult Neurogenesis Beyond Rats and Mice

Adult Neurogenesis  Beyond Rats and Mice
Author: Luca Bonfanti,Irmgard Amrein
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2019-02-11
ISBN 10: 2889457613
ISBN 13: 9782889457618
Language: EN, FR, DE, ES & NL

Adult Neurogenesis Beyond Rats and Mice Book Review:

Researchers working on adult neurogenesis have focused largely on inbred laboratory rodents. While this provides a strong advantage of restricting genetic variation in the group, it also narrows our perspective on adult neurogenesis as a biological phenomenon. Many unsolved issues and open questions cannot be resolved without the contribution of comparative studies spanning through widely different species: how did adult neurogenesis evolve, what is the link between adult neurogenesis and brain complexity, how do adult neurogenesis and animal behavior influence each other, how does adult neurogenesis contribute to brain plasticity, cognition and, possibly, repair, and how do experimental conditions affect adult neurogenesis. The main message from the comparative approach to adult neurogenesis is that the relative exclusive focus on laboratory rodents can result in a bias on how we think about this biological process.