Motor Neuron Disorders

Motor Neuron Disorders
Author: Pamela J. Shaw,Michael J. Strong
Publsiher: Butterworth-Heinemann Medical
Total Pages: 569
Release: 2003
ISBN 10:
ISBN 13: UOM:39015060031468
Language: EN, FR, DE, ES & NL

Motor Neuron Disorders Book Review:

This book includes state-of-the-art discussions of the pathogenesis of amyotrophic lateral sclerosis; new information on the genetic basis and clinical management of spinal muscular atrophy; current understanding of Kennedy's disease; and recent findings on hereditary spastic paraparesis. This book will deliver the guidance the reader needs to accurately diagnose any type of motor neuron disorder and manage it using effective methods.

Motor Neuron Disease in Adults

Motor Neuron Disease in Adults
Author: Mark Bromberg
Publsiher: Oxford University Press
Total Pages: 352
Release: 2014-10-02
ISBN 10: 0190202262
ISBN 13: 9780190202262
Language: EN, FR, DE, ES & NL

Motor Neuron Disease in Adults Book Review:

Motor Neuron Disease in Adults reviews new information as it applies to all aspects of motor neuron disease (ALS, PLS, PMA). The choice of articles is for those that use evidence-based methods to ensure that the new information is solid and advances the topic or issue. The book can be used by anyone who provides any type of care to ALS patients. In particular, neurologists will find the latest information on diagnosis and management, as well as new information on genetics and frontotemporal lobe involvement. Allied health providers will find useful information for their discipline. Patients will also find both specific and general information to help understand what they are experiencing and how to help manage their symptoms.

Molecular and Cellular Therapies for Motor Neuron Diseases

Molecular and Cellular Therapies for Motor Neuron Diseases
Author: Nicholas M Boulis,Deirdre O’Connor,Anthony Donsante
Publsiher: Academic Press
Total Pages: 336
Release: 2017-01-18
ISBN 10: 0128025247
ISBN 13: 9780128025246
Language: EN, FR, DE, ES & NL

Molecular and Cellular Therapies for Motor Neuron Diseases Book Review:

Molecular and Cellular Therapies for Motor Neuron Diseases discusses the basics of the diseases, also covering advances in research and clinical trials. The book provides a resource for students that will help them learn the basics in a detailed manner that is required for scientists and clinicians. Users will find a comprehensive overview of the background of Amyotrophic Lateral Sclerosis (ALS/Lou Gehrig’s Disease) and Spinal Muscular Atrophy (SMA), along with the current understanding of their genetics and mechanisms. In addition, the book details gene and cell therapies that have been developed and their translation to clinical trials. Provides an overview of gene and cell therapies for amyotrophic lateral sclerosis (ALS) and other motor neuron diseases Edited by a leading Neurosurgeon and two research scientists to promote synthesis between basic neuroscience and clinical relevance Presents a great resource for researchers and practitioners in neuroscience, neurology, and gene and cell therapy

Clinical Neurophysiology of Motor Neuron Diseases

Clinical Neurophysiology of Motor Neuron Diseases
Author: Andrew Eisen
Publsiher: Elsevier Science Health Science Division
Total Pages: 724
Release: 2004
ISBN 10: 9780444513595
ISBN 13: 0444513590
Language: EN, FR, DE, ES & NL

Clinical Neurophysiology of Motor Neuron Diseases Book Review:

The volume summarizes the most recent knowledge in the field of motor system (upper and lower motor neuron) physiology and pathophysiology as related to diseases of this system. It covers the various aspects of motor system disorders from the motor cortex to the spinal anterior horn cell. Emphasis is placed on clinical disorders as they affect the human motor system and includes critical discussion of advances in techniques for diagnosing and understanding the pathophysiology of disorders affecting the motor system, describing approaches to characterization of disease type, location, severity and prognosis. There is discussion of the specificity and sensitivity of methodological techniques used in diagnosis, with comparison among the various methods.

Motor Neuron Diseases

Motor Neuron Diseases
Author: Bradley J. Turner
Publsiher: Nova Science Pub Incorporated
Total Pages: 244
Release: 2014-01-01
ISBN 10: 9781631173424
ISBN 13: 1631173421
Language: EN, FR, DE, ES & NL

Motor Neuron Diseases Book Review:

Motor neuron disease (MND), also commonly known as amyotrophic lateral sclerosis (ALS), is a chronic neurodegenerative disorder of the motor system in adults, characterized by the loss of motor neurons in the cortex, brain stem and spinal cord. This book presents current research from across the globe in the study of the causes, classification and treatments of MND, including membrane trafficking defects as determinants of motor neuron susceptibility and degeneration in ALS; motorneuron specific calcium dysregulation and perturbed cellular calcium homeostasis in ALS; stem cells and their application in ALS treatment; excitotoxicity and selective motor neuron degeneration and therapeutic invervention and assistive technology treatments. (Imprint: Nova Biomedical)

Neurodegeneration

Neurodegeneration
Author: Ted M. Dawson
Publsiher: John Wiley & Sons
Total Pages: 344
Release: 2017-04-24
ISBN 10: 0470672684
ISBN 13: 9780470672686
Language: EN, FR, DE, ES & NL

Neurodegeneration Book Review:

This book unites the diverse range of complex neurodegenerative diseases into a textbook designed for clinical practice, edited by globally leading authorities on the subject. Presents a clinically oriented guide to the diseases caused by neurodegeneration Templated chapters combine clinical and research information on neurodegenerative diseases beginning with the common elements before treating each disease individually Diseases are grouped by anatomical regions of degeneration and include common disorders such as Parkinson’s Disease, Alzheimer’s Disease, Amyotrophic Lateral Sclerosis/Motor Neuron Disease, and Multiple Sclerosis as well as less common diseases Edited by globally leading authorities on the subject, and written by expert contributing authors

The Management of Motor Neurone Disease

The Management of Motor Neurone Disease
Author: George M. Cochrane
Publsiher: Unknown
Total Pages: 104
Release: 1987
ISBN 10:
ISBN 13: UOM:39015012536432
Language: EN, FR, DE, ES & NL

The Management of Motor Neurone Disease Book Review:

Motor Neuron Disease

Motor Neuron Disease
Author: Kevin Talbot,Rachael Marsden,Rachel Botell
Publsiher: Oxford University Press
Total Pages: 214
Release: 2010
ISBN 10: 019954736X
ISBN 13: 9780199547364
Language: EN, FR, DE, ES & NL

Motor Neuron Disease Book Review:

Written and designed to provide comprehensive, easily accessible advice for all healthcare professionals involved in the care of patients with this challenging condition, this book addresses the entire care pathway from presentation to diagnosis to symptom management and end of life issues.

Motor Neuron Disease

Motor Neuron Disease
Author: P.N. Leigh,Michael Swash
Publsiher: Springer Science & Business Media
Total Pages: 468
Release: 2012-12-06
ISBN 10: 1447118715
ISBN 13: 9781447118718
Language: EN, FR, DE, ES & NL

Motor Neuron Disease Book Review:

Here is the first book to provide a comprehensive overview of the clinical, pathological, and research aspects of motor neuron disease (MND). The text contains all essential features of the anatomy, physiology, pharmacology and toxicology of the motor system, a full description of MND and its variants, as well as historical developments and a review of the current concepts and controversies. This book comes at a time of increasing interest in neurodegenerative disorders and MND in particular. It will prove a key reference book with an integrated overview of the field, and will be indispensable to practicing neurologists, researchers, and all those with an interest in MND.

Clinical and Molecular Aspects of Motor Neuron Disease

Clinical and Molecular Aspects of Motor Neuron Disease
Author: Johnathan Cooper-Knock,Thomas Jenkins,Pamela J. Shaw
Publsiher: Biota Publishing
Total Pages: 60
Release: 2013-09-01
ISBN 10: 1615044299
ISBN 13: 9781615044290
Language: EN, FR, DE, ES & NL

Clinical and Molecular Aspects of Motor Neuron Disease Book Review:

In this e-book, motor neuron disease (MND) shall refer to amyotrophic lateral sclerosis (ALS), the most common neurodegenerative disorder affecting both the upper and lower motor neurons. With the discovery of C9ORF72 expansions in approximately 10% of all MND cases, in certain populations, we stand at the brink of a new era of MND research and hopefully treatment facilitated by the ability to associate a relatively large group of patients with a similar disease mechanism. This review will summarise both current clinical management of MND and our present understanding of the molecular pathogenesis of MND. Study of C9ORF72-MND has the potential to rapidly advance both of these aspects in the coming years.

Update on Amyotrophic Lateral Sclerosis

Update on Amyotrophic Lateral Sclerosis
Author: Humberto Foyaca Sibat,Lourdes de Fátima Ibañez-Valdés
Publsiher: BoD – Books on Demand
Total Pages: 280
Release: 2016-09-14
ISBN 10: 9535126008
ISBN 13: 9789535126003
Language: EN, FR, DE, ES & NL

Update on Amyotrophic Lateral Sclerosis Book Review:

This book contains selected peer-reviewed chapters which cover updated information on ALS written by international researchers. Update on Amyotrophic Lateral Sclerosis is comprised of 13 chapters from some of the world's top central nervous system researchers and neurologists to provide a timely review of the most recent developments in ALS, covering historic aspects, experimental animal models, genetics, pathogenesis, clinical aspects and imagenology among others. Contributors from Belgium, France, Japan, India, Italy, Mexico, Russia, South Africa, and Switzerland have collaborated enthusiastically and efficiently, dedicating their time to create this reader-friendly yet comprehensive work which includes many explanatory figures, tables and photos to enhance legibility and make the book clinically useful. We are looking forward with confidence and pride in the remarkable role that this book will play for a new vision and mission.

Practical Guide to Neurogenetics E Book

Practical Guide to Neurogenetics E Book
Author: Thomas T. Warner,Simon R. Hammans
Publsiher: Elsevier Health Sciences
Total Pages: 344
Release: 2008-11-04
ISBN 10: 0702038458
ISBN 13: 9780702038457
Language: EN, FR, DE, ES & NL

Practical Guide to Neurogenetics E Book Book Review:

This simple guide to neurogenetics demystifies the overwhelming amount of information on the subject so you can identify key clinical features and understand your management options. Reach relevant differential diagnoses and provide appropriate counseling to your patients using the symptom-based approach. By integrating genetic and neurological approaches to diagnoses, this book ensures that the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis are clear and explicit. Concise and portable, this book is ideal for easy reference in clinical use. Details the underlying basic science and clinical features of genetic disorders by taking a symptom-based approach to provide you with a comprehensive understanding of the field. Focuses on the clinical application of neurogenetics to be of practical use to you in the clinic. Clarifies the neurological consequences of a genetic diagnosis and the genetic consequences of a neurological diagnosis by integrating genetic and neurological approaches to diagnoses. Discusses and evaluates necessary investigations so you know when to use them and when to refer. Highlights diagnostic and therapeutic tips so you can learn new concepts or refine your skills in practice. Refers to online sources, such as Online Mendelian Inheritance in Man (OMIM) and others, to help you supplement your knowledge.

Current Advances in Amyotrophic Lateral Sclerosis

Current Advances in Amyotrophic Lateral Sclerosis
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2013
ISBN 10: 9789535171799
ISBN 13: 9535171798
Language: EN, FR, DE, ES & NL

Current Advances in Amyotrophic Lateral Sclerosis Book Review:

Motor Neuron Disease in Adults

Motor Neuron Disease in Adults
Author: Mark B. Bromberg
Publsiher: Oxford University Press, USA
Total Pages: 336
Release: 2014-10-28
ISBN 10: 019978311X
ISBN 13: 9780199783113
Language: EN, FR, DE, ES & NL

Motor Neuron Disease in Adults Book Review:

Motor Neuron Disease in Adults reviews new information as it applies to all aspects of motor neuron disease (ALS, PLS, PMA). The choice of articles is for those that use evidence-based methods to ensure that the new information is solid and advances the topic or issue. The book can be used by anyone who provides any type of care to ALS patients. In particular, neurologists will find the latest information on diagnosis and management, as well as new information on genetics and frontotemporal lobe involvement. Allied health providers will find useful information for their discipline. Patients will also find both specific and general information to help understand what they are experiencing and how to help manage their symptoms.

Prognosis of Neurological Diseases

Prognosis of Neurological Diseases
Author: Angelo Sghirlanzoni,Giuseppe Lauria,Luisa Chiapparini
Publsiher: Springer
Total Pages: 519
Release: 2015-11-19
ISBN 10: 8847057558
ISBN 13: 9788847057555
Language: EN, FR, DE, ES & NL

Prognosis of Neurological Diseases Book Review:

This book offers clear, detailed guidance on all aspects of prognostic evaluation in patients who have been involved in a serious accident with neurological consequences or have been diagnosed with a severe neurological illness. It covers the full range of disorders of the central and the peripheral nervous system, not only providing very accurate prognostic estimates but also addressing relevant clinical issues, differential diagnosis, and the role of imaging. The book is practically oriented and designed for use on a daily basis when assessing prognosis and discussing the outcome with patients, their families, and other interested parties. It will support patient–doctor partnerships by ensuring that the most professional answers can be given to patients' and doctors' questions and by promoting realistic expectations of the effect of medical interventions. In addition, it will enable doctors, lawyers, and other professionals to understand relevant issues when an estimate of prognosis and life expectancy is the subject of legal dispute.

Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis

Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis
Author: Ricardo Tapia
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2015-02-11
ISBN 10: 2889193764
ISBN 13: 9782889193769
Language: EN, FR, DE, ES & NL

Cellular and molecular mechanisms of motor neuron death in amyotrophic lateral sclerosis Book Review:

Amyotrophic lateral sclerosis (ALS), which was described since 1869 by Jean Martin Charcot, is a devastating neurodegenerative disease characterized by the selective and progressive loss of upper and lower motor neurons of the cerebral cortex, brainstem and the spinal cord. The cognitive process is not affected and is not merely the result of aging because may occur at young ages. The only known cause of the disease is associated with genetic mutations, mainly in the gene encoding superoxide dismutase 1 (familial ALS), whereas there is no known cause of the sporadic form of ALS (SALS), which comprises >90% of cases. Both ALS types develop similar histopathological and clinical characteristics, and there is no treatment or prevention of the disease. Because effective treatments for ALS, as for other neurodegenerative diseases, can only result from the knowledge of their cellular and molecular pathophysiological mechanisms, research on such mechanisms is essential. Although progress in neurochemical, physiological and clinical investigations in the last decades has identified several mechanisms that seem to be involved in the cell death process, such as glutamate-mediated excitotoxicity, alterations of inhibitory circuits, inflammatory events, axonal transport deficits, oxidative stress, mitochondrial dysfunction and energy failure, the understanding of the origin and temporal progress of the disease is still incomplete and insufficient. Clearly, there is a need of further experimental models and approaches to discern the importance of such mechanisms and to discover the factors that determine the selective death of motor neurons characteristic of ALS, in contrast to other neurodegenerative diseases such as Parkinson’s and Alzheimer’s disease. Whereas studies in vitro in cell cultures, tissue slices or organotypic preparations can give useful information regarding cellular and molecular mechanisms, the experiments in living animal models obviously reflect more closely the situation in the human disease, provided that the symptoms and their development during time mimics as close as possible those of the human disease. It is necessary to correlate the experimental findings in vitro with those in vivo, as well as those obtained in genetic models with those in non-genetic models, aiming at designing and testing therapeutic strategies based on the results obtained.

Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases

Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases
Author: Lewis P. Rowland
Publsiher: Raven Press (ID)
Total Pages: 569
Release: 1991
ISBN 10:
ISBN 13: UOM:39015020987445
Language: EN, FR, DE, ES & NL

Amyotrophic Lateral Sclerosis and Other Motor Neuron Diseases Book Review:

A collection of invited papers from a Muscular Dystrophy Association sponsored symposium which highlight findings and theories on the molecular genetics of these diseases, assess concepts on immune-mediated motor neuron destruction and examine the pathogenesis of motor neuron disease.

Amyotrophic Lateral Sclerosis

Amyotrophic Lateral Sclerosis
Author: Muralidhar L. Hegde
Publsiher: BoD – Books on Demand
Total Pages: 160
Release: 2020-08-26
ISBN 10: 183880580X
ISBN 13: 9781838805807
Language: EN, FR, DE, ES & NL

Amyotrophic Lateral Sclerosis Book Review:

A flurry of recent research on the role of the RNA/DNA-binding proteins TDP-43 and FUS as well as a dozen other factors (e.g., C9ORF72 and profilin) has led to a new paradigm in our understanding of the pathobiology of the motor neuron disease, Amyotrophic Lateral Sclerosis (ALS). How these factors trigger neuromuscular dysfunction is critical for developing more effective ALS therapeutics. The ‘gain-of-toxicity’ or ‘loss-of-function’ of these etiological factors is a key question. Recent studies on the imbalance in genome damage versus repair have opened avenues for potential DNA repair-based therapeutics. This book highlights emerging science in the area of ALS and discusses key approaches and mechanisms essential for developing a cure for ALS.

Motor Neuron Disease

Motor Neuron Disease
Author: Kevin Talbot,Rachael Marsden
Publsiher: Oxford University Press
Total Pages: 151
Release: 2008-01-03
ISBN 10: 0199206910
ISBN 13: 9780199206919
Language: EN, FR, DE, ES & NL

Motor Neuron Disease Book Review:

Approximately 5,000-6,000 people have motor neuron disease (MND) in the UK at any one time. It is a devastating disability that has a profound impact on people's lives. Addressing frequently asked questions about the disease, this book provides clear information on understanding the causes of the disease and how to gain support and symptom control.

Motor Neutron Diseases

Motor Neutron Diseases
Author: Forbes Holten Norris,Leonard T. Kurland
Publsiher: Unknown
Total Pages: 329
Release: 1969
ISBN 10:
ISBN 13: OCLC:225953291
Language: EN, FR, DE, ES & NL

Motor Neutron Diseases Book Review: