Molecular Imaging

Molecular Imaging
Author: Brian D. Ross,Sanjiv S. Gambhir
Publsiher: Academic Press
Total Pages: 1868
Release: 2021-08-09
ISBN 10: 0128163879
ISBN 13: 9780128163870
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

The detection and measurement of the dynamic regulation and interactions of cells and proteins within the living cell are critical to the understanding of cellular biology and pathophysiology. The multidisciplinary field of molecular imaging of living subjects continues to expand with dramatic advances in chemistry, molecular biology, therapeutics, engineering, medical physics and biomedical applications. Molecular Imaging: Principles and Practice, Volumes 1 and 2, Second Edition provides the first point of entry for physicians, scientists, and practitioners. This authoritative reference book provides a comprehensible overview along with in-depth presentation of molecular imaging concepts, technologies and applications making it the foremost source for both established and new investigators, collaborators, students and anyone interested in this exciting and important field. The most authoritative and comprehensive resource available in the molecular-imaging field, written by over 170 of the leading scientists from around the world who have evaluated and summarized the most important methods, principles, technologies and data Concepts illustrated with over 600 color figures and molecular-imaging examples Chapters/topics include, artificial intelligence and machine learning, use of online social media, virtual and augmented reality, optogenetics, FDA regulatory process of imaging agents and devices, emerging instrumentation, MR elastography, MR fingerprinting, operational radiation safety, multiscale imaging and uses in drug development This edition is packed with innovative science, including theranostics, light sheet fluorescence microscopy, (LSFM), mass spectrometry imaging, combining in vitro and in vivo diagnostics, Raman imaging, along with molecular and functional imaging applications Valuable applications of molecular imaging in pediatrics, oncology, autoimmune, cardiovascular and CNS diseases are also presented This resource helps integrate diverse multidisciplinary concepts associated with molecular imaging to provide readers with an improved understanding of current and future applications

Essentials of Nuclear Medicine and Molecular Imaging E Book

Essentials of Nuclear Medicine and Molecular Imaging E Book
Author: Fred A. Mettler,Milton J. Guiberteau
Publsiher: Elsevier Health Sciences
Total Pages: 624
Release: 2018-08-17
ISBN 10: 0323567894
ISBN 13: 9780323567893
Language: EN, FR, DE, ES & NL

Essentials of Nuclear Medicine and Molecular Imaging E Book Book Review:

Covering both the fundamentals and recent developments in this fast-changing field, Essentials of Nuclear Medicine and Molecular Imaging, 7th Edition, is a must-have resource for radiology residents, nuclear medicine residents and fellows, nuclear medicine specialists, and nuclear medicine technicians. Known for its clear and easily understood writing style, superb illustrations, and self-assessment features, this updated classic is an ideal reference for all diagnostic imaging and therapeutic patient care related to nuclear medicine, as well as an excellent review tool for certification or MOC preparation. Provides comprehensive, clear explanations of everything from principles of human physiology, pathology, physics, radioactivity, radiopharmaceuticals, radiation safety, and legal requirements to hot topics such as new brain and neuroendocrine tumor agents and hybrid imaging, including PET/MR and PET/CT. Covers the imaging of every body system, as well as inflammation, infection and tumor imaging; pearls and pitfalls for every chapter; and pediatric doses and guidelines in compliance with the Image Gently and Image Wisely programs. Features a separate self-assessment section on differential diagnoses, imaging procedures and artifacts, and safety issues with unknown cases, questions, answers, and explanations. Includes new images and illustrations, for a total of 430 high-quality, multi-modality examples throughout the text. Reflects recent advances in the field, including updated nuclear medicine imaging and therapy guidelines • Updated dosimetry values and effective doses for all radiopharmaceuticals with new values from the 2015 International Commission on Radiological Protection • Updated information regarding advances in brain imaging, including amyloid, dopamine transporter and dementia imaging • Inclusion of Ga-68 DOTA PET/CT for neuroendocrine tumors • Expanded information on correlative and hybrid imaging with SPECT/CT • New myocardial agents • and more. Contains extensive appendices including updated comprehensive imaging protocols for routine and hybrid imaging, pregnancy and breastfeeding guidelines, pediatric dosages, non-radioactive pharmaceuticals used in interventional and cardiac stress imaging, and radioactivity conversion tables.

Molecular Imaging

Molecular Imaging
Author: Ralph Weissleder
Publsiher: PMPH-USA
Total Pages: 1357
Release: 2010
ISBN 10: 9781607950059
ISBN 13: 1607950057
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

The field of molecular imaging of living subjects have evolved considerably and have seen spectacular advances in chemistry, engineering and biomedical applications. This textbook was designed to fill the need for an authoritative source for this multi-disciplinary field. We have been fortunate to recruit over 80 leading authors contributing 75 individual chapters. Given the multidisciplinary nature of the field, the book is broken into six different sections: "Molecular Imaging technologies", "Chemistry", "Molecular Imaging in Cell and Molecular Biology", "Applications of Molecular Imaging", "Molecular Imaging in Drug Evaluation" with the final section comprised of chapters on computation, bioinformatics and modeling. The organization of this large amount of information is logical and strives to avoid redundancies among chapters. It encourages the use of figures to illustrate concepts and to provide numerous molecular imaging examples.

Molecular Imaging

Molecular Imaging
Author: Ammasi Periasamy,Richard Day
Publsiher: Elsevier
Total Pages: 312
Release: 2011-04-28
ISBN 10: 9780080536873
ISBN 13: 0080536875
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

The detection and measurement of the dynamic interactions of proteins within the living cell are critical to our understanding of cell physiology and pathophysiology. With FRET microscopy and spectroscopy techniques, basic and clinical scientists can make such measurements at very high spatial and temporal resolution. But sources of background information about these tools are very limited, so this book fills an important gap. It covers both the basic concepts and theory behind the various FRET microscopy and spectroscopy techniques, and the practical aspects of using the techniques and analyzing the results. The critical tricks for obtaining a good FRET image and precisely quantitating the signals from living specimens at the nanomolecular level are explained. Valuable information about the preparation of biological samples used for FRET image analysis is also provided. The methods covered include different types of microscopy systems and detectors (wide-field, confocal, multi-photon) as well as specialized techniques such as photobleaching FRET, FLIM-FRET microscopy, spectral imaging FRET, single molecule FRET, and time and image correlation spectroscopy. Starting from the basics, the chapters guide readers through the choice of probes to be used for FRET experiments and the selection of the most suitable experimental approaches to address specific biological questions. Up-to-date, consistently organized, and well-illustrated, this unique book will be welcomed by all researchers who wish to use FRET microscopy and spectroscopy techniques.

Molecular Imaging II

Molecular Imaging II
Author: Wolfhard Semmler,Markus Schwaiger
Publsiher: Springer
Total Pages: 365
Release: 2010-11-30
ISBN 10: 9783642096099
ISBN 13: 3642096093
Language: EN, FR, DE, ES & NL

Molecular Imaging II Book Review:

The aim of this textbook of molecular imaging is to provide an up to date review of this rapidly growing field and to discuss basic methodological aspects necessary for the interpretation of experimental and clinical results. Emphasis is placed on the interplay of imaging technology and probe development, since the physical properties of the imaging approach need to be closely linked with the biologic application of the probe (i.e. nanoparticles and microbubbles). Various chemical strategies are discussed and related to the biologic applications. Reporter-gene imaging is beeing addressed not only in experimental protocols, but also first clinical applications are discussed. Finally, strategies of imaging to characterize apoptosis and angiogenesis are described and discussed in the context of possible clinical translation.

Molecular Imaging in Oncology

Molecular Imaging in Oncology
Author: Otmar Schober,Burkhard Riemann
Publsiher: Springer Science & Business Media
Total Pages: 416
Release: 2012-11-28
ISBN 10: 3642108539
ISBN 13: 9783642108532
Language: EN, FR, DE, ES & NL

Molecular Imaging in Oncology Book Review:

The impact of molecular imaging on diagnostics, therapy, and follow-up in oncology is increasing steadily. Many innovative molecular imaging probes have already entered clinical practice, and there is no doubt that the future emphasis will be on multimodality imaging in which morphological, functional, and molecular imaging techniques are combined in a single clinical investigation. This handbook addresses all aspects of molecular imaging in oncology, from basic research to clinical applications. The first section is devoted to technology and probe design, and examines a variety of PET and SPECT tracers as well as multimodality probes. Preclinical studies are then discussed in detail, with particular attention to multimodality imaging. In the third section, diverse clinical applications are presented, and the book closes by looking at future challenges. This handbook will be of value to all who are interested in the revolution in diagnostic oncology that is being brought about by molecular imaging.

Emerging Applications of Molecular Imaging to Oncology

Emerging Applications of Molecular Imaging to Oncology
Author: Anonim
Publsiher: Elsevier
Total Pages: 402
Release: 2014-09-27
ISBN 10: 0124116345
ISBN 13: 9780124116344
Language: EN, FR, DE, ES & NL

Emerging Applications of Molecular Imaging to Oncology Book Review:

Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics. This volume, number 124, covers emerging applications of molecular imaging to oncology, including molecular-genetic imaging, imaging the tumor microenvironment, tracking cells and vaccines in vivo, and more. Provides information on cancer research Outstanding and original reviews Suitable for researchers and students

Molecular Imaging Basic Principles And Applications In Biomedical Research 3rd Edition

Molecular Imaging  Basic Principles And Applications In Biomedical Research  3rd Edition
Author: Markus Rudin
Publsiher: World Scientific
Total Pages: 800
Release: 2020-04-04
ISBN 10: 1786346869
ISBN 13: 9781786346865
Language: EN, FR, DE, ES & NL

Molecular Imaging Basic Principles And Applications In Biomedical Research 3rd Edition Book Review:

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied.The third edition has been extended considerably. This holds for the chapter on imaging modalities, which now includes sections on intravital microscopy and mass spectrometric imaging. All chapters have been updated and a new chapter on the challenges of translating molecular imaging solutions for clinical use has been added.

Molecular Imaging in Parkinson s Disease

Molecular Imaging in Parkinson s Disease
Author: Cristina Polito
Publsiher: Firenze University Press
Total Pages: 68
Release: 2011
ISBN 10: 886655037X
ISBN 13: 9788866550372
Language: EN, FR, DE, ES & NL

Molecular Imaging in Parkinson s Disease Book Review:

Targeted Molecular Imaging in Oncology

Targeted Molecular Imaging in Oncology
Author: E. Edmund Kim,David J. Yang
Publsiher: Springer Science & Business Media
Total Pages: 289
Release: 2001
ISBN 10: 9780387950280
ISBN 13: 0387950281
Language: EN, FR, DE, ES & NL

Targeted Molecular Imaging in Oncology Book Review:

Cancer cells dedifferentiate with repect to cell function; their vascularity is more leaky, but perfusion is heterogenerously reduced, and interstitial fluid pressure is high, severely retarding delivery of agents from the blood. Targeted imaging is designed to produce a detectable difference between tissue that is visualized with single photon and positron emission tomography, magnetic resonance imaging, computed tomography, or ultrasonography. This book uniquely reports strategies for the application of molecular targeted imaging agents such as antibodies, peptides, receptors and contrast agents in the biologic grading of tumors, differential diagnosis of tumors, prediction of therapeutic response and monitoring tumor response to treatment. This book also describes updated information about the imaging of tumor angiogenesis, hypoxia, apoptosis and gene delivery as well as expression in the understanding and utility of tumor molecular biology for better cancer management.

Molecular Imaging with Reporter Genes

Molecular Imaging with Reporter Genes
Author: Sanjiv Sam Gambhir,Shahriar S. Yaghoubi
Publsiher: Cambridge University Press
Total Pages: 135
Release: 2010-05-31
ISBN 10: 1139489526
ISBN 13: 9781139489522
Language: EN, FR, DE, ES & NL

Molecular Imaging with Reporter Genes Book Review:

Reporter genes have been used for several decades to study regulation of gene expression in vivo. However, it was little more than a decade ago that a new class of reporter genes was developed for imaging molecular events within living subjects. By following the interactions of protein molecules, researchers can resolve the complex chemical pathways that living cells utilise. This book focuses on this group of imaging reporter genes, starting with detailed descriptions of all reporter genes from different imaging modalities, including optical, MRI, and radionuclide-based imaging. Key scientists in the field explain how to enhance reporter gene imaging utility through instrumentation and the various applications of this technology. This is the first comprehensive book on all aspects of reporter gene imaging, detailing what is known in the field and future goals for research. Investigators in biomedical sciences, physicians, and the biotechnology and pharmaceutical industries will benefit from topics covered.

The Chemistry of Molecular Imaging

The Chemistry of Molecular Imaging
Author: Nicholas Long,Wing-Tak Wong,Edmund H. Immergut
Publsiher: John Wiley & Sons
Total Pages: 408
Release: 2014-12-22
ISBN 10: 1118093275
ISBN 13: 9781118093276
Language: EN, FR, DE, ES & NL

The Chemistry of Molecular Imaging Book Review:

Covering all the fundamentals of modern imaging methodologies, including their techniques and application within medicine and industry, The Chemistry of Molecular Engineering focuses primarily on the chemistry of probes and imaging agents, as well as chemical methodology for labelling and bioconjugation. Written by an interdisciplinary team of experts, this book investigates the chemistry of molecular imaging and helps to educate non-chemists already involved in the area of molecular imaging. It addresses all the major modalities and techniques, such as MRI, positron emission tomography, single photon emission computed tomography, ultrasound, and fluorescence/optical imaging.

Essentials of Nuclear Medicine Imaging

Essentials of Nuclear Medicine Imaging
Author: Fred A. Mettler,Milton J. Guiberteau
Publsiher: Saunders
Total Pages: 391
Release: 1986
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015072194387
Language: EN, FR, DE, ES & NL

Essentials of Nuclear Medicine Imaging Book Review:

The Chemistry of Molecular Imaging

The Chemistry of Molecular Imaging
Author: Nicholas Long,Wing-Tak Wong
Publsiher: John Wiley & Sons
Total Pages: 408
Release: 2014-12-01
ISBN 10: 1118854772
ISBN 13: 9781118854778
Language: EN, FR, DE, ES & NL

The Chemistry of Molecular Imaging Book Review:

Molecular imaging is primarily about the chemistry of novelbiological probes, yet the vast majority of practitioners are notchemists or biochemists. This is the first book, written from achemist's point of view, to address the nature of the chemicalinteraction between probe and environment to help elucidatebiochemical detail instead of bulk anatomy. Covers all of the fundamentals of modern imaging methodologies,including their techniques and application within medicine andindustry Focuses primarily on the chemistry of probes and imagingagents, and chemical methodology for labelling andbioconjugation First book to investigate the chemistry of molecularimaging Aimed at students as well as researchers involved in the areaof molecular imaging

Pediatric Nuclear Medicine and Molecular Imaging

Pediatric Nuclear Medicine and Molecular Imaging
Author: S.Ted. Treves
Publsiher: Springer
Total Pages: 712
Release: 2014-05-16
ISBN 10: 1461495512
ISBN 13: 9781461495512
Language: EN, FR, DE, ES & NL

Pediatric Nuclear Medicine and Molecular Imaging Book Review:

This pioneering book, now in its fourth edition, presents the cutting-edge developments in pediatric nuclear medicine. Thoroughly revised and updated, it retains the fundamentals that anchor the book’s distinguished reputation and includes the latest advances in PET/CT, SPECT, hybrid imaging, and molecular imaging. Pediatric Nuclear Medicine and Molecular Imaging, Fourth Edition, is an excellent resource for nuclear medicine physicians, diagnostic radiologists, pediatricians, and residents and fellows. The Fourth Edition features: · 16 new chapters, including PET and PET/CT in Children and Young Adults; Lymphoscintigraphy; Skeletal Scintigraphy; Neuroblastoma; Lymphomas and Lymphoproliferative Disorders; Functional Imaging of Pediatric Musculoskeletal Tumors; Solid Tumors in Childhood; Pediatric Molecular Imaging; Combined PET/MRI in Childhood; Radiation Exposures; Radiation Protection in Pediatric Nuclear Medicine; and Dose Optimization in Pediatric Nuclear Medicine. · Discussion of the use of image fusion and hybrid imaging in children. · Strategies for communicating potential radiation risk to patients, families and members of the healthcare team. · Methods to optimize pediatric radiopharmaceutical administered doses and improve image quality. S. Ted Treves, MD, is Professor of Radiology at Harvard Medical School, Founder and Former Chief, Division of Nuclear Medicine and Molecular Imaging, Ch ildren’s Hospital Boston (1970-2011). In 2013, he received the Society of Nuclear Medicine and Molecular Imaging’s Georg Charles de Hevesy Nuclear Pioneer Award for outstanding contributions to the field of Nuclear Medicine.

Molecular Imaging

Molecular Imaging
Author: Shankar Vallabhajosula
Publsiher: Springer Science & Business Media
Total Pages: 372
Release: 2009-07-13
ISBN 10: 3540767355
ISBN 13: 9783540767350
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

Radioisotope-based molecular imaging probes provide unprecedented insight into biochemistry and function involved in both normal and disease states of living systems, with unbiased in vivo measurement of regional radiotracer activities offering very high specificity and sensitivity. No other molecular imaging technology including functional magnetic resonance imaging (fMRI) can provide such high sensitivity and specificity at a tracer level. The applications of this technology can be very broad ranging from drug development, pharmacokinetics, clinical investigations, and finally to routine diagnostics in radiology. The design and the development of radiopharmaceuticals for molecular imaging studies using PET/MicroPET or SPECT/MicroSPECT are a unique challenge. This book is intended for a broad audience and written with the main purpose of educating the reader on various aspects including potential clinical utility, limitations of drug development, and regulatory compliance and approvals.

Molecular Imaging of Small Animals

Molecular Imaging of Small Animals
Author: Habib Zaidi
Publsiher: Springer
Total Pages: 760
Release: 2014-05-28
ISBN 10: 9781493908936
ISBN 13: 1493908936
Language: EN, FR, DE, ES & NL

Molecular Imaging of Small Animals Book Review:

This book examines the fundamental concepts of multimodality small-animal molecular imaging technologies and their numerous applications in biomedical research. Driven primarily by the widespread availability of various small-animal models of human diseases replicating accurately biological and biochemical processes in vivo, this is a relatively new yet rapidly expanding field that has excellent potential to become a powerful tool in biomedical research and drug development. In addition to being a powerful clinical tool, a number of imaging modalities including but not limited to CT, MRI, SPECT and PET are also used in small laboratory animal research to visualize and track certain molecular processes associated with diseases such as cancer, heart disease and neurological disorders in living small animal models of disease. In vivo small-animal imaging is playing a pivotal role in the scientific research paradigm enabling to understand human molecular biology and pathophysiology using, for instance, genetically engineered mice with spontaneous diseases that closely mimic human diseases.

Molecular Imaging Basic Principles And Applications In Biomedical Research 2nd Edition

Molecular Imaging  Basic Principles And Applications In Biomedical Research  2nd Edition
Author: Rudin Markus
Publsiher: World Scientific
Total Pages: 620
Release: 2013-07-04
ISBN 10: 1783263172
ISBN 13: 9781783263172
Language: EN, FR, DE, ES & NL

Molecular Imaging Basic Principles And Applications In Biomedical Research 2nd Edition Book Review:

The area of molecular imaging has matured over the past decade and is still growing rapidly. Many concepts developed for molecular biology and cellular imaging have been successfully translated to in vivo imaging of intact organisms. Molecular imaging enables the study of processes at a molecular level in their full biological context. Due to the high specificity of the molecular readouts the approach bears a high potential for diagnostics. It is fair to say that molecular imaging has become an indispensable tool for biomedical research and drug discovery and development today.This volume familiarizes the reader with the concepts of imaging and molecular imaging in particular. Basic principles of imaging technologies, reporter moieties for the various imaging modalities, and the design of targeted probes are described in the first part. The second part illustrates how these tools can be used to visualize relevant molecular events in the living organism. Topics covered include the studies of the biodistribution of reporter probes and drugs, visualization of the expression of biomolecules such as receptors and enzymes, and how imaging can be used for analyzing consequences of the interaction of a ligand or a drug with its molecular target by visualizing signal transduction, or assessing the metabolic, physiological, or structural response of the organism studied. The final chapter deals with visualization of cell migration, for example in the context of cell therapies.The second edition covers novel developments over recent years, in particular regarding imaging technologies (hybrid techniques) and novel reporter concepts. Novel biomedical applications have been included, where appropriate. All the chapters have been thoroughly reworked and the artwork updated.

Nuclear Medicine and Molecular Imaging the Requisites

Nuclear Medicine and Molecular Imaging  the Requisites
Author: Janis P. O'Malley,Harvey A. Ziessman
Publsiher: Elsevier
Total Pages: 464
Release: 2019-11
ISBN 10: 9780323530378
ISBN 13: 0323530370
Language: EN, FR, DE, ES & NL

Nuclear Medicine and Molecular Imaging the Requisites Book Review:

Now in its 5th Edition, this outstanding volume in the popular Requisites series thoroughly covers the fast-changing field of nuclear medicine and molecular imaging. Ideal for residency, clinical rotations, and board review, this compact and authoritative volume by Drs. Janis O'Malley and Harvey Ziessman covers the conceptual, factual, and interpretive information you need to know for success on exams and in clinical practice. NEW to this edition: More content on molecular imaging and the latest advances in clinical applications, including positron emission tomography (PET), SPECT/CT, PET/CT, and PET/MRI hybrid imaging. Inclusion of newly approved tracers such as Ga68 DOTA, F-18 amyloid, and F-18 PSMA. Expanded and integrated content on physics and non-interpretive aspects, including regulatory issues, radiation safety, and quality control. Up-to-date applications of nuclear medicine in the endocrine, skeletal, hepatobiliary, genitourinary, pulmonary, gastrointestinal, central nervous, and cardiac systems, as well as PET applications for oncology. In the outstanding Requisites tradition, the 5th Edition also: Summarizes key information with numerous outlines, tables, pearls, pitfalls, and frequently asked questions. Focuses on essentials to pass the certifying board exam and ensure accurate diagnoses in clinical practice. Helps you clearly visualize the findings you're likely to see in practice and on exams with nearly 200 full-color images. Expert ConsultT eBook version included with purchase. This enhanced eBook experience allows you to search all the text, figures, and references from the book on a variety of electronic devices.

Molecular Imaging

Molecular Imaging
Author: Hossein Jadvar,Michael Graham,Heather Jacene
Publsiher: Cambridge University Press
Total Pages: 94
Release: 2017-10-31
ISBN 10: 1107621283
ISBN 13: 9781107621282
Language: EN, FR, DE, ES & NL

Molecular Imaging Book Review:

Trace the history, and advances in the field of molecular imaging, with this guide to the visual world of disease.