Molecular Biology of B Cells

Molecular Biology of B Cells
Author: Tasuku Honjo
Publsiher: Academic Press
Total Pages: 600
Release: 2014-11-01
ISBN 10: 9780123979339
ISBN 13: 0123979331
Language: EN, FR, DE, ES & NL

Molecular Biology of B Cells Book Review:

Molecular Biology of B Cells, Second Edition is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All of these developmental and stimulatory processes are described in molecular, immunological, and genetic terms to give a clear understanding of complex phenotypes. Molecular Biology of B Cells, Second Edition offers an integrated view of all aspects of B cells to produce a normal immune response as a constant, and the molecular basis of numerous diseases due to B cell abnormality. The new edition continues its success with updated research on microRNAs in B cell development and immunity, new developments in understanding lymphoma biology, and therapeutic targeting of B cells for clinical application. With updated research and continued comprehensive coverage of all aspects of B cell biology, Molecular Biology of B Cells, Second Edition is the definitive resource, vital for researchers across molecular biology, immunology and genetics. Covers signaling mechanisms regulating B cell differentiation Provides information on the development of therapeutics using monoclonal antibodies and clinical application of Ab Contains studies on B cell tumors from various stages of B lymphocytes Offers an integrated view of all aspects of B cells to produce a normal immune response

Molecular Biology of B Cells

Molecular Biology of B Cells
Author: Michael Reth,Andreas Radbruch,Frederick Alt,Tasuku Honjo,Michael Neuberger
Publsiher: Elsevier
Total Pages: 600
Release: 2004-02-19
ISBN 10: 9780080479507
ISBN 13: 0080479502
Language: EN, FR, DE, ES & NL

Molecular Biology of B Cells Book Review:

Molecular Biology of B Cells is a comprehensive reference to how B cells are generated, selected, activated and engaged in antibody production. All these developmental and stimulatory processes are described in molecular and genetic terms to give a clear understanding of complex phenotyes. The molecular basis of many diseases due to B cell abnormality is also discussed. This definitive reference is directed at research level immunologists, molecular biologists and geneticists.

B Cell Protocols

B Cell Protocols
Author: Hua Gu,Klaus Rajewsky
Publsiher: Humana Press
Total Pages: 292
Release: 2010-10-28
ISBN 10: 9781617375101
ISBN 13: 1617375101
Language: EN, FR, DE, ES & NL

B Cell Protocols Book Review:

B-lymphocyte development and function remains an exciting area of research for those interested in the physiology and pathology of the immune system in higher animals. While recent advances in genetics and cellular and molecular biology have provided a large spectrum of powerful new experimental tools in this field, it is both time consuming and often very difficult for a student or just any bench-side worker to identify a reliable experimental protocol in the ocean of the literature. The aim of B Cell Protocols is to provide a collection of diverse protocols ranging from the latest inventions and applications to some classic, but still frequently used methods in B-cell biology. The authors of the various chapters are all highly qualified scientists who are either the inventors or expert users of these methods. Their extensive experience in mastering a particular method provides not only the step-by-step details of a reproducible protocol, but also useful troubleshooting tips that readers will appreciate in their daily work. We hope that this book will be helpful for both beginning and experienced researchers in the field in designing or modifying an experimental approach, and exploring a biological question from multiple angles.

Molecular Biology of B Cell and T Cell Development

Molecular Biology of B Cell and T Cell Development
Author: John G. Monroe,Ellen Rothenberg
Publsiher: Springer Science & Business Media
Total Pages: 587
Release: 2013-03-14
ISBN 10: 147572778X
ISBN 13: 9781475727784
Language: EN, FR, DE, ES & NL

Molecular Biology of B Cell and T Cell Development Book Review:

Despite the tremendous diversity of the cells of the hematopoietic system, they are all derived from common precursor cells that are generated in the fetus and persist into adult life. In this regard, Band T lymphocytes, which comprise the two arms of the antigen-specific and inducible immune system, though functionally very different, are descendants of the same stem cell precursor. In the past several years, we have witnessed an explosion of information regarding the process by which differentiation of B-and T-cells from stem cells occurs. This information, like the answers to most important biological questions, has come from multiple and diverse directions. Because all hematopoietic cells arise from common precursors, complex regulatory processes must be involved in determining commitment to various lineages. Understanding commitment to the B- or T-cell lineage remains incomplete; however, identification of transcription factors necessary for progression along specific B-and T-cell pathways suggests that we are on the verge of understanding the molecules involved in the initial fate-determining steps. Studies of this type previously could be accomplished only in nonmammalian systems that are more amenable to genetic approaches. However, new technologies allow increasingly elegant and informative studies in mammalian systems, particularly for cells of the hematopoietic system.

Regulatory B Cells

Regulatory B Cells
Author: Francesca Mion,Silvia Tonon
Publsiher: Humana
Total Pages: 471
Release: 2021-01-22
ISBN 10: 9781071612361
ISBN 13: 1071612360
Language: EN, FR, DE, ES & NL

Regulatory B Cells Book Review:

This second edition provides new and updated chapters useful for the study of Regulatory B cells. Organized in four sections, chapters detail basic methods for the isolation and immunophenotypical analysis of these cells, experimental approaches for the ex vivo generation/expansion of IL-10 producing B cells, molecular biology techniques for the analysis of IL-10 expression and production, and animal models mimicking pathologic settings. Written in the highly successful Methods in Molecular Biology series format, chapters include an introduction to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, as well as tips on troubleshooting and avoiding known pitfalls. Authoritative and cutting-edge, Regulatory B Cells: Methods and Protocols, Second Edition aims to be useful to the scientific community and serve to clarify some unsolved aspects of Regulatory B Cells research.

Immunoglobulin Genes

Immunoglobulin Genes
Author: Tasuku Honjo,Frederick W. Alt
Publsiher: Academic Press
Total Pages: 443
Release: 2012-12-02
ISBN 10: 0080984487
ISBN 13: 9780080984483
Language: EN, FR, DE, ES & NL

Immunoglobulin Genes Book Review:

Immunoglobin Genes is the first comprehensive book on the structure, function, and expression of the genes encoding antibodies in normal and neoplastic cells.

Molecular Biology of the Cell

Molecular Biology of the Cell
Author: Bruce Alberts
Publsiher: Unknown
Total Pages: 329
Release: 2004
ISBN 10: 9780815332183
ISBN 13: 0815332181
Language: EN, FR, DE, ES & NL

Molecular Biology of the Cell Book Review:

B Cells

B Cells
Author: Robert L. Montes,Leo Reyes
Publsiher: Nova Biomedical
Total Pages: 92
Release: 2013-01-01
ISBN 10: 9781628085419
ISBN 13: 162808541X
Language: EN, FR, DE, ES & NL

B Cells Book Review:

B cells belong to a group of white blood cells known as lymphocytes, making them a vital part of the immune system. The human body makes millions of different types of B cells each day that circulate in the blood and lymphatic system performing the role of immune surveillance. They do not produce antibodies until they become fully activated. In this book, the authors present current research in the study of the molecular biology, developmental origin and impact on the immune system of B cells. Topics discussed include the role of B cells in intracellular bacterial pathogen infections; dynamic clustering of BCR-lipid rafts in antigen affinity discrimination by B cells; and B cells as a key player in the pathogenesis of multiple sclerosis.

Molecular Biology of the Cell 6E The Problems Book

Molecular Biology of the Cell 6E   The Problems Book
Author: John Wilson,Tim Hunt
Publsiher: Garland Science
Total Pages: 984
Release: 2014-11-21
ISBN 10: 1317497279
ISBN 13: 9781317497271
Language: EN, FR, DE, ES & NL

Molecular Biology of the Cell 6E The Problems Book Book Review:

The Problems Book helps students appreciate the ways in which experiments and simple calculations can lead to an understanding of how cells work by introducing the experimental foundation of cell and molecular biology. Each chapter reviews key terms, tests for understanding basic concepts, and poses research-based problems. The Problems Book has be

T and B Lymphocytes Recognition and Function

T and B Lymphocytes  Recognition and Function
Author: Fritz Bach
Publsiher: Elsevier
Total Pages: 736
Release: 2012-12-02
ISBN 10: 0323142842
ISBN 13: 9780323142847
Language: EN, FR, DE, ES & NL

T and B Lymphocytes Recognition and Function Book Review:

T and B Lymphocytes: Recognition and Function is the 16th volume of the 1979 ICN-UCLA Symposia on Molecular and Cellular Biology. This book is organized into seven sections, encompassing 74 chapters that summarize molecular level progress in the field of immunobiology. It emphasizes cell membrane, techniques developed for its analysis, and varied products of the major histocompatibility complex, as well as other receptors on cells of the immune system. The book starts by describing two approaches for molecular association evaluation. First is the use of artificial membranes or lipid vesicles for the incorporation of antigens for recognition by T-lymphocytes both at the afferent and efferent levels. Second is the chemical crosslinking of cell surface components with a variety of different crosslinking reagents. This is followed by a discussion on the molecular nature of a T-cell receptor that provides insights of the target(s) recognized by T-lymphocytes. Several chapters discuss data dealing with the issue of the apparent differential recognition by T- and B-cells while both use the same VH genes. Antiidiotypic sera, together with the activity of ""regulator"" T-cells, are also discussed, with regard to their role in networks of regulation of the immune response. This book presents works demonstrating that human T-lymphocytes can also be cloned and both noncytotoxic proliferating T-lymphocytes and Tc can be so obtained. This is along with the continuing studies regarding heterogenity of B-lymphocytes as well as macrophages. Part V focuses on the interaction between lymphocyte and virus and molecular modifications of viral-infected cells. The subsequent section deals with recognition, reactivities, and function of T- and B-lymphocytes. Considerable chapters in this section discuss T-cell cytotoxicity, dichotomy of MHC control over anti H-Y cytotoxic T-cell responses, mouse alloantibodies, and mixed lymphocyte reactions. The concluding part describes immunological tools, such as synthetic membranes and cloned T-cells with biological function.

Molecular and Cellular Biology of Viruses

Molecular and Cellular Biology of Viruses
Author: Phoebe Lostroh
Publsiher: Garland Science
Total Pages: 501
Release: 2019-05-06
ISBN 10: 0429664303
ISBN 13: 9780429664304
Language: EN, FR, DE, ES & NL

Molecular and Cellular Biology of Viruses Book Review:

Viruses interact with host cells in ways that uniquely reveal a great deal about general aspects of molecular and cellular structure and function. Molecular and Cellular Biology of Viruses leads students on an exploration of viruses by supporting engaging and interactive learning. All the major classes of viruses are covered, with separate chapters for their replication and expression strategies, and chapters for mechanisms such as attachment that are independent of the virus genome type. Specific cases drawn from primary literature foster student engagement. End-of-chapter questions focus on analysis and interpretation with answers being given on the website (half for students, all for instructors). Examples come from the most-studied and medically important viruses such as HIV, influenza, and poliovirus. Plant viruses and bacteriophages are also included. There are chapters on the overall effect of viral infection on the host cell. Coverage of the immune system is focused on the interplay between host defenses and viruses, with a separate chapter on medical applications such as anti-viral drugs and vaccine development. The final chapter is on virus diversity and evolution, incorporating contemporary insights from metagenomic research. Key selling feature: Readable but rigorous coverage of the molecular and cellular biology of viruses Molecular mechanisms of all major groups, including plant viruses and bacteriophages, illustrated by example Host-pathogen interactions at the cellular and molecular level emphasized throughout Medical implications and consequences included Quality illustrations available to instructors Extensive questions and answers for each chapter

Janeway s Immunobiology

Janeway s Immunobiology
Author: Ken Murphy
Publsiher: Unknown
Total Pages: 800
Release: 2007
ISBN 10: 9780203852538
ISBN 13: 0203852532
Language: EN, FR, DE, ES & NL

Janeway s Immunobiology Book Review:

Janeway's Immunobiology, Seventh Edition is an introductory text for use in immunology courses for undergraduates, graduate students and medical students. It guides the reader through the immune system in all its aspects - from the first engagement of innate immunity to the generation of the adaptive immune response and its clinical con

B Lymphocytes

B Lymphocytes
Author: G. G. B. Klaus
Publsiher: Oxford University Press
Total Pages: 71
Release: 1990
ISBN 10:
ISBN 13: UOM:39015021997989
Language: EN, FR, DE, ES & NL

B Lymphocytes Book Review:

This book provides a timely review of our current knowledge of the cellular and molecular biology of B lymphocytes. These cells play a key role in the immune system. B cells recognize antigens by means of specific cell surface antibody molecules, and in recent years there has been rapid progress in our understanding of these responses. Considerable advances have also been made in unravelling the regulation of B cell activation by T cells and the cytokines they produce, and how microenvironmental factors determine whether B cells become antibody-producing cell or memory cells. Intended for undergraduates and graduate students in biology and medicine, this work covers new topics and ideas not adequately covered in existing textbooks. It provides in-depth knowledge in an easy-to-read format, with two-color diagrams for increased clarity.

The Neuron

The Neuron
Author: Irwin B. Levitan,Leonard K. Kaczmarek
Publsiher: Oxford University Press, USA
Total Pages: 603
Release: 2002
ISBN 10: 9780195145236
ISBN 13: 0195145232
Language: EN, FR, DE, ES & NL

The Neuron Book Review:

Intended for use by advanced undergraduate, graduate and medical students, this book presents a study of the unique biochemical and physiological properties of neurons, emphasising the molecular mechanisms that generate and regulate their activity.

B Cell Biology in Autoimmunity

B Cell Biology in Autoimmunity
Author: David Ahmad Nemazee
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 272
Release: 2003
ISBN 10: 3805574541
ISBN 13: 9783805574549
Language: EN, FR, DE, ES & NL

B Cell Biology in Autoimmunity Book Review:

B cells play a central role not only in adaptive immunity, but also in autoimmunity. To understand how B cells are normally prevented from reacting to self-tissue, what goes wrong in autoimmunity, and how B cells contribute to it is the aim of this book. This volume includes more than a dozen in-depth reviews by researchers specializing in various aspects of basic B cell biology that have relevance to autoimmune diseases. These up-to-date chapters present the latest information on B cell signal transduction, apoptosis, genetics and molecular biology. Also featured are chapters with special reference to particular autoimmune diseases in which B cells have been shown to play a critical role, such as type 1 diabetes, chronic graft-versus-host disease and lupus erythematosus. Further topics covered include the role of the complement system, rheumatoid factors, and anti-DNA autoantibodies as well as important related areas such as natural autoantibodies, B cell immune tolerance, Toll receptor signaling, and the immunobiology of BAFF/BLyS. Both basic researchers and clinician scientists who wish to understand the role of B lymphocytes in immune tolerance and autoimmunity will benefit from this timely publication.

Molecular Biology of B Cell Developments

Molecular Biology of B Cell Developments
Author: Clemens Sorg
Publsiher: S Karger Ag
Total Pages: 174
Release: 1990
ISBN 10:
ISBN 13: UOM:39015018864820
Language: EN, FR, DE, ES & NL

Molecular Biology of B Cell Developments Book Review:

B Cells

B Cells
Author: Robert L. Montes,Leo Reyes
Publsiher: Unknown
Total Pages: 329
Release: 2013-09-13
ISBN 10: 9781223075365
ISBN 13: 1223075362
Language: EN, FR, DE, ES & NL

B Cells Book Review:

Lymphocyte Activation and Differentiation

Lymphocyte Activation and Differentiation
Author: J. C. Mani,J. Dornand
Publsiher: Walter de Gruyter GmbH & Co KG
Total Pages: 981
Release: 2019-08-07
ISBN 10: 3110850257
ISBN 13: 9783110850253
Language: EN, FR, DE, ES & NL

Lymphocyte Activation and Differentiation Book Review:

Lymphocytes

Lymphocytes
Author: Erman Salih Istifli,Hasan Basri İla
Publsiher: BoD – Books on Demand
Total Pages: 124
Release: 2019-01-16
ISBN 10: 1789849195
ISBN 13: 9781789849196
Language: EN, FR, DE, ES & NL

Lymphocytes Book Review:

Although all the features of the immune system have not been fully resolved yet, the knowledge we have gained from studies on lymphocytes, the basic elements of the immune system, is quite lucid. For this reason, the significance of lymphocytes (the cells that are the source of most of the information we have obtained about the human genome, the negative effects of drugs on the genetic system, the development and behavior of immune system, antigen-antibody association, cytotoxic adaptive immunity, antibody-driven adaptive immunity, cancer and autoimmune diseases) is clear. Studies on lymphocytes will not only help us develop tools to combat human diseases more effectively in the future, but will also help us understand how evolution shapes the immune system in living organisms.

Cells Molecules and Mechanisms

Cells  Molecules and Mechanisms
Author: E.V. Wong
Publsiher: Axolotl Academic Publishing
Total Pages: 283
Release: 2009
ISBN 10: 0985226110
ISBN 13: 9780985226114
Language: EN, FR, DE, ES & NL

Cells Molecules and Mechanisms Book Review: