Mitochondrial Metabolism

Mitochondrial Metabolism
Author: Jalal Pourahmad,Mohsen Rezaei
Publsiher: Academic Press
Total Pages: 416
Release: 2021-07-01
ISBN 10: 0128224096
ISBN 13: 9780128224090
Language: EN, FR, DE, ES & NL

Mitochondrial Metabolism Book Review:

Mitochondrial Metabolism: An Approach for Disease Management covers mitotherapy from three combined perspectives, Pharmacology, Toxicology and Biochemistry. After an introduction from world-renowned experts, the book's chapters cover the balancing role in reduction/oxidation mitochondria play, mitochondria as targets for therapeutics through its metabolism, mitochondrial contributions to the cell death process, mitochondrial response to environmental toxicants, the mitochondrial role in aging, the impact of calorie restrictive diets, new advances in the identification of altered mitochondria associated signaling pathways in carcinogenesis, and much more. This book provides bioscientists new horizons to realize the importance of mitochondria in present-day research on therapies dealing with mitochondria associated chronic diseases, including diabetes, cancer and neurodegenerative disorders. Details the significant role of mitochondria in chronic diseases Presents new insights on the targeting of mitochondria for therapeutic purposes Includes updated results on mitotherapy and other mitochondria-oriented therapies

Mitochondrial Medicine

Mitochondrial Medicine
Author: Salvatore DiMauro,Michio Hirano,Eric A. Schon
Publsiher: CRC Press
Total Pages: 16
Release: 2019-11-29
ISBN 10: 9780367446369
ISBN 13: 0367446367
Language: EN, FR, DE, ES & NL

Mitochondrial Medicine Book Review:

Mitochondrial dysfunction is increasingly being recognized as the basis of a wide variety of human diseases. Providing an authoritative update on our current knowledge of mitochondrial medicine, this text draws together world authorities from various fields to present general therapeutic strategies, as well as the treatments presently available in different specialties - thus making it essential reading for clinicians involved with the management of patients with mitochondrial diseases. A unique work, this text covers a range of specialties, including cardiology, ophthalmology, otology, nephrology, gastroenterology, hematology-oncology, and reproductive medicine, and does not focus exclusively on the more commonly known neurologic conditions. An accessible, user-friendly text, it also presents translational concepts of mitochondrial biogenesis and genetics in vignettes related to specific questions raised by the disease under discussion, rather than concentrating on basic science, which can often intimidate clinicians. This pioneering work is primarily directed to a clinical audience who are interested in the diverse and diagnostically challenging clinical presentations of mitochondrial diseases and their pathophysiology.

Cancer as a Metabolic Disease

Cancer as a Metabolic Disease
Author: Thomas Seyfried
Publsiher: John Wiley & Sons
Total Pages: 438
Release: 2012-05-18
ISBN 10: 1118310306
ISBN 13: 9781118310304
Language: EN, FR, DE, ES & NL

Cancer as a Metabolic Disease Book Review:

The book addresses controversies related to the origins of cancerand provides solutions to cancer management and prevention. Itexpands upon Otto Warburg's well-known theory that all cancer is adisease of energy metabolism. However, Warburg did not linkhis theory to the "hallmarks of cancer" and thus his theory wasdiscredited. This book aims to provide evidence, throughcase studies, that cancer is primarily a metabolic diseaserequring metabolic solutions for its management andprevention. Support for this position is derived fromcritical assessment of current cancer theories. Brain cancercase studies are presented as a proof of principle for metabolicsolutions to disease management, but similarities are drawn toother types of cancer, including breast and colon, due tothe same cellular mutations that they demonstrate.

Update on Dementia

Update on Dementia
Author: Davide Moretti
Publsiher: BoD – Books on Demand
Total Pages: 558
Release: 2016-09-28
ISBN 10: 9535126547
ISBN 13: 9789535126546
Language: EN, FR, DE, ES & NL

Update on Dementia Book Review:

The dementia challenge is the largest health effort of the times we live in. The whole society has to move to a realization of the significance of prioritization to make an attempt in the direction of mental health promotion and dementia risk reduction. New priorities for research are needed to go far beyond the usual goal of constructing a disease course-modifying medication. Moreover, a full empowerment and engagement of men and women living with dementia and their caregivers, overcoming stigma and discrimination should be promoted. The common efforts and the final aim will have to be the progress of a ''dementia-constructive'' world, where people with dementia can take advantage of equal opportunities.

Mitochondrial Diseases

Mitochondrial Diseases
Author: Eylem Taskin,Celal Guven,Yusuf Sevgiler
Publsiher: BoD – Books on Demand
Total Pages: 496
Release: 2018-08-29
ISBN 10: 1789236746
ISBN 13: 9781789236743
Language: EN, FR, DE, ES & NL

Mitochondrial Diseases Book Review:

Mitochondria are crucial organelles for any cell type. Mitochondria take responsibility for not only energy production but also regulation of cell death, also called apoptosis; calcium storage; and heat production. Therefore, mitochondrial disease is implicated in the mode of action of many harmful factors for cells such as drugs and environmental contaminants, dysfunction of the oxygen transport system, malnutrition, intense exercise, and genetic variations. This book presents up-to-date knowledge about mitochondrial disease and its complex relation to some diseases such as cardiac failure, cancer, and Alzheimer's and Parkinson's diseases. This book will, therefore, be essential for readers who are interested in life sciences, especially in medicine.

Research Grants Index

Research Grants Index
Author: National Institutes of Health (U.S.). Division of Research Grants
Publsiher: Unknown
Total Pages: 329
Release: 1974
ISBN 10:
ISBN 13: MINN:31951D03457590Z
Language: EN, FR, DE, ES & NL

Research Grants Index Book Review:

Research Awards Index

Research Awards Index
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1984
ISBN 10:
ISBN 13: MINN:31951000193619S
Language: EN, FR, DE, ES & NL

Research Awards Index Book Review:

Clinical Bioenergetics

Clinical Bioenergetics
Author: Sergej M. Ostojic
Publsiher: Academic Press
Total Pages: 716
Release: 2020-11-12
ISBN 10: 0128227729
ISBN 13: 9780128227725
Language: EN, FR, DE, ES & NL

Clinical Bioenergetics Book Review:

Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others. Provides a thorough discussion of foundational aspects of bioenergetics and disease, modes of analysis, and treatments for impaired bioenergetics Discusses the role of bioenergetics and treatment pathways in brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among other diseases and disorders Features chapter contributions from international leaders in translational bioenergetics research and clinical practice

Mitochondria in Liver Disease

Mitochondria in Liver Disease
Author: Derick Han,Neil Kaplowitz
Publsiher: CRC Press
Total Pages: 485
Release: 2015-10-28
ISBN 10: 1482236982
ISBN 13: 9781482236989
Language: EN, FR, DE, ES & NL

Mitochondria in Liver Disease Book Review:

"...excellent, well-organized, and timely." —Lester Packer and Enrique Cardenas, University of Southern California, Los Angeles, from the Series Preface The liver is a vital organ that is responsible for a wide range of functions, most of which are essential for survival. The multitude of functions the liver performs makes it vulnerable to a wide range of diseases. Mitochondrial dysfunction plays an important role in many liver diseases including drug-induced liver injury, alcoholic liver disease, and nonalcoholic fatty liver disease. Mitochondria in Liver Disease gathers the most current research regarding the role of mitochondria in the liver and various diseases to which it is susceptible. The book is separated into two sections, the first of which highlights the latest developments in mitochondrial research. It includes cutting-edge topics such as the regulation of mitochondrial respiration using hydrogen sulfide and the regulation of mitochondrial fusion–fission via the endoplasmic reticulum. The second section reviews the most current research on the role of mitochondria in a wide range of liver diseases. It also addresses novel topics such as the importance of liver mitochondrial constituents as biomarkers of liver injury in plasma and as regulators of the immune system. Mitochondria in Liver Disease represents the current state of knowledge and research on mitochondrial roles in liver diseases. Written by a group of global experts, it provides an authoritative and comprehensive overview of the latest advances and methods that mark key starting points for future research.

Mitochondrial Mechanisms of Degeneration and Repair in Parkinson s Disease

Mitochondrial Mechanisms of Degeneration and Repair in Parkinson s Disease
Author: Lori M. Buhlman
Publsiher: Springer
Total Pages: 275
Release: 2016-09-13
ISBN 10: 3319421395
ISBN 13: 9783319421391
Language: EN, FR, DE, ES & NL

Mitochondrial Mechanisms of Degeneration and Repair in Parkinson s Disease Book Review:

This volume brings together various theories of how aberrations in mitochondrial function and morphology contribute to neurodegeneration in idiopathic and familial forms of Parkinson’s disease. Moreover, it comprehensively reviews the current search for therapies, and proposes how molecules are involved in specific functions as attractive therapeutic targets. It is expected to facilitate critical thought and discussion about the fundamental aspects of neurodegeneration in Parkinson’s disease and foster the development of therapeutic strategies among researchers and graduate students. Theories of idiopathic Parkinson’s etiology support roles for chronic inflammation and exposure to heavy metals or pesticides. Interestingly, as this project proposes, a case can be made that abnormalities in mitochondrial morphology and function are at the core of each of these theories. In fact, the most common approach to the generation of animal and cell-culture models of idiopathic Parkinson’s disease involves exposure to mitochondrial toxins. Even more compelling is the fact that most familial patients harbor genetic mutations that cause disruptions in normal mitochondrial morphology and function. While there remains to be no effective treatment for Parkinson’s disease, efforts to postpone, prevent and “cure” onset mitochondrial aberrations and neurodegeneration associated with Parkinson’s disease in various models are encouraging. While only about ten percent of Parkinson’s patients inherit disease-causing mutations, discovering common mechanisms by which familial forms of Parkinson’s disease manifest will likely shed light on the pathophysiology of the more common idiopathic form and provide insight to the general process of neurodegeneration, thus revealing therapeutic targets that will become more and more accessible as technology improves.

Mitochondrial Medicine

Mitochondrial Medicine
Author: Anna Gvozdjáková
Publsiher: Springer Science & Business Media
Total Pages: 409
Release: 2008-02-01
ISBN 10: 9781402067143
ISBN 13: 1402067143
Language: EN, FR, DE, ES & NL

Mitochondrial Medicine Book Review:

Mitochondrial medicine deals with diseases that are related to mitochondrial dysfunction due to a number of causes from free radical damage to genetic mutation. This book is based on extensive data gathered over 30 years of clinical and experimental research. In it, internationally recognized authors share their experience in various fields of their expertise and guide readers through the disease process, from basic biochemical mechanisms to diagnosis to therapeutic aspects.

Mitochondrial DNA and Diseases

Mitochondrial DNA and Diseases
Author: Hongzhi Sun,Xiangdong Wang
Publsiher: Springer
Total Pages: 230
Release: 2017-11-25
ISBN 10: 9811066744
ISBN 13: 9789811066740
Language: EN, FR, DE, ES & NL

Mitochondrial DNA and Diseases Book Review:

The book describes molecular principles and mechanisms by which mitochondrial DNA (mtDNA) can drive the occurrence of diseases and the latest understanding of mtDNA biology. The book explores roles of mtDNA mutation and genetic changes in cancer, with a special focus on lung cancer, and the significance of approach, application, and bioethics of mtDNA sequencing. Authors made a great effort to overview roles of mtDNA signaling pathways, base excision repair, methylation, USP30-mediated regulation, mitochondrial ribosome, autophagy pathways, or ROS-dependent signaling in the pathogenesis, diagnosis, prevention and treatment of diseases. It also demonstrates the importance of basic mitochondrial genetics and the relationship between mutations and disease phenotypes and ageing. This book covers not only the basic information of mtDNA, the relationship of mtDNA and disease, but also mtDNA in stem cell and mitochondria and metabolism etc. The book is written for biological and clinical students and researchers in the field of mtDNA–associated diseases.

Inherited Metabolic Diseases

Inherited Metabolic Diseases
Author: Georg F. Hoffmann,Johannes Zschocke,William L. Nyhan
Publsiher: Springer Science & Business Media
Total Pages: 386
Release: 2009-11-21
ISBN 10: 9783540747239
ISBN 13: 3540747230
Language: EN, FR, DE, ES & NL

Inherited Metabolic Diseases Book Review:

The explosion of insights in the field of metabolic disease has shed new light on diagnostic as well as treatment options. ‘Inherited Metabolic Disease – A Clinical Approach’ is written with a reader-friendly consistent structure. It helps the reader to find the information in an easily accessible and rapid way when needed. Starting with an overview of the major groups of metabolic disorders it includes algorithms with questions and answers as well as numerous graphs, metabolic pathways, and an expanded index. Clinical and diagnostic details with a system and symptom based are given to facilitate an efficient and yet complete diagnostic work-up of individual patients. Further, it offers helpful advice for emergency situations, such as hypoglycemia, hyperammonemia, lactic acidosis or acute encephalopathy. Five different indices allow a quick but complete orientation for common important constellations. Last but not least, it has an appendix with a guide to rapid differential diagnosis of signs and symptoms and when not to suspect metabolic disease. It will help physicians to diagnose patients they may otherwise fail to diagnose and to reduce unnecessary referrals. For metabolic and genetic specialists especially the indices will be helpful as a quick look when being called for advice. It has all it needs to become a gold standard defining the clinical practice in this field.

Mitochondrial Case Studies

Mitochondrial Case Studies
Author: Russell Saneto,Sumit Parikh,Bruce H Cohen
Publsiher: Academic Press
Total Pages: 338
Release: 2015-11-24
ISBN 10: 0128011491
ISBN 13: 9780128011492
Language: EN, FR, DE, ES & NL

Mitochondrial Case Studies Book Review:

Mitochondrial Case Studies: Underlying Mechanisms and Diagnosis offers the science behind mitochondrial disease with a case studies approach. Since mitochondrial diseases are diverse and influenced by genetic, environmental, and social-economic factors, this publication will help students, physicians, scientists, health care students, and families recognize and accurately diagnose mitochondrial disease and learn about potential treatments. Reviews case studies as a helpful teaching tool to increase awareness and improve diagnosis Provides information on underlying mechanisms of mitochondrial disease Includes basic mitochondrial dysfunction research through patient case studies to best illustrate the entire disease process

Metabolic Diseases Approach to diagnosis of metabolic diseases

Metabolic Diseases  Approach to diagnosis of metabolic diseases
Author: Enid Gilbert-Barness,Lewis A. Barness
Publsiher: Eaton Publishing Company/Biotechniques Books
Total Pages: 890
Release: 2000
ISBN 10:
ISBN 13: UOM:39015049510970
Language: EN, FR, DE, ES & NL

Metabolic Diseases Approach to diagnosis of metabolic diseases Book Review:

Developmental Disabilities in Infancy and Childhood Neurodevelopmental diagnosis and treatment

Developmental Disabilities in Infancy and Childhood  Neurodevelopmental diagnosis and treatment
Author: Arnold J. Capute,Pasquale J. Accardo
Publsiher: Paul H Brookes Publishing Company
Total Pages: 630
Release: 1996
ISBN 10: 9781557661784
ISBN 13: 1557661782
Language: EN, FR, DE, ES & NL

Developmental Disabilities in Infancy and Childhood Neurodevelopmental diagnosis and treatment Book Review:

The second edition, now in two volumes rather than one, contains some 30 new chapters addressing a greatly increased number of topics and range of issues, from a variety of disciplines. The first volume offers discussion of general issues in the theory, assessment, and treatment of developmental dis

Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondrial Disease

Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondrial Disease
Author: Iain P. Hargreaves
Publsiher: MDPI
Total Pages: 238
Release: 2018-10-16
ISBN 10: 3038972401
ISBN 13: 9783038972402
Language: EN, FR, DE, ES & NL

Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondrial Disease Book Review:

This book is a printed edition of the Special Issue "Current Strategies for the Biochemical Diagnosis and Monitoring of Mitochondrial Disease" that was published in JCM

A Practical Approach to the Spectrum of Alcoholic Liver Disease An Issue of Clinics in Liver Disease E Book

A Practical Approach to the Spectrum of Alcoholic Liver Disease  An Issue of Clinics in Liver Disease   E Book
Author: David Bernstein
Publsiher: Elsevier Health Sciences
Total Pages: 240
Release: 2012-11-14
ISBN 10: 1455747378
ISBN 13: 9781455747375
Language: EN, FR, DE, ES & NL

A Practical Approach to the Spectrum of Alcoholic Liver Disease An Issue of Clinics in Liver Disease E Book Book Review:

The Guest Editor has organized this issue to focus on the clinical management of alcoholic liver disease. Authors have written state-of-the-art reviews on the following topics: Prevalence and Natural History of ALD; Alcohol Metabolism; Immunology in ALD; Histological Findings in ALD; Diagnosis and Management of Alcoholic Hepatitis; Management of Alcohol Abuse; Long Term Management of Alcoholic Liver Disease; Infections in ALD; Nutrition in ALD; Alcohol’s Effect on Other Chronic Liver Diseases; Liver Cancer and Alcohol; Evaluation and Selection of Candidates for Liver Transplantation; and ALD and Specific Transplant-Related Issues.

Complementary Therapies for the Body Mind and Soul

Complementary Therapies for the Body  Mind and Soul
Author: Marcelo Saad
Publsiher: BoD – Books on Demand
Total Pages: 296
Release: 2015-09-02
ISBN 10: 9535121588
ISBN 13: 9789535121589
Language: EN, FR, DE, ES & NL

Complementary Therapies for the Body Mind and Soul Book Review:

Complementary Therapies (CT) refers to the practices, products, or health systems that are outside the realm of conventional medicine, used to treat disease or to promote health and well-being. Defining CT is difficult, because the field is very broad and constantly changing. The title of this book includes the words body, mind, and soul. The body and the mind (and their reciprocal relations) have been extensively studied scientifically. What about the soul? The book brings some points about this new ground in CT. We hope you find in the present work the sincere desire to collaborate with the dissemination of knowledge. May this book be useful and pleasant to you.

Mitochondria in Obesity and Type 2 Diabetes

Mitochondria in Obesity and Type 2 Diabetes
Author: Beatrice Morio,Luc Penicaud,Michel Rigoulet
Publsiher: Academic Press
Total Pages: 736
Release: 2019-04-15
ISBN 10: 0128117524
ISBN 13: 9780128117521
Language: EN, FR, DE, ES & NL

Mitochondria in Obesity and Type 2 Diabetes Book Review:

Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers. Synthesizes actual knowledge on mitochondrial function Provides an integrated vision of each tissue in the etiology of obesity and type 2 diabetes Identifies the interactive networks that involve alteration in mitochondrial mass and function in disease progression Highlights the role played by mitochondria in the prevention and treatment of obesity and type 2 diabetes