Mitochondrial Case Studies

Mitochondrial Case Studies
Author: Russell Saneto
Publsiher: Academic Press
Total Pages: 336
Release: 2015-12-11
ISBN 10: 9780128008775
ISBN 13: 0128008776
Language: EN, FR, DE, ES & NL

Mitochondrial Case Studies Book Review:

Mitochondrial Case Studies: Underlying Mechanisms and Diagnosis offers the science behind mitochondrial disease with a case studies approach. Since mitochondrial diseases are diverse and influenced by genetic, environmental, and social-economic factors, this publication will help students, physicians, scientists, health care students, and families recognize and accurately diagnose mitochondrial disease and learn about potential treatments. Reviews case studies as a helpful teaching tool to increase awareness and improve diagnosis Provides information on underlying mechanisms of mitochondrial disease Includes basic mitochondrial dysfunction research through patient case studies to best illustrate the entire disease process

Mitochondrial Case Studies

Mitochondrial Case Studies
Author: Russell Saneto,Sumit Parikh,Bruce H Cohen
Publsiher: Academic Press
Total Pages: 338
Release: 2015-11-24
ISBN 10: 0128011491
ISBN 13: 9780128011492
Language: EN, FR, DE, ES & NL

Mitochondrial Case Studies Book Review:

Mitochondrial Case Studies: Underlying Mechanisms and Diagnosis offers the science behind mitochondrial disease with a case studies approach. Since mitochondrial diseases are diverse and influenced by genetic, environmental, and social-economic factors, this publication will help students, physicians, scientists, health care students, and families recognize and accurately diagnose mitochondrial disease and learn about potential treatments. Reviews case studies as a helpful teaching tool to increase awareness and improve diagnosis Provides information on underlying mechanisms of mitochondrial disease Includes basic mitochondrial dysfunction research through patient case studies to best illustrate the entire disease process

Mitochondrial DNA Control Region Sequences Used for Identification of Species in Two Forensic Science Case Studies

Mitochondrial DNA Control Region Sequences Used for Identification of Species in Two Forensic Science Case Studies
Author: Kevin Dee Rittenhouse
Publsiher: Unknown
Total Pages: 86
Release: 1996
ISBN 10:
ISBN 13: OCLC:36391106
Language: EN, FR, DE, ES & NL

Mitochondrial DNA Control Region Sequences Used for Identification of Species in Two Forensic Science Case Studies Book Review:

Mitochondrial Medicine

Mitochondrial Medicine
Author: Pankaj Prasun
Publsiher: Academic Press
Total Pages: 138
Release: 2019-05-18
ISBN 10: 0128170077
ISBN 13: 9780128170076
Language: EN, FR, DE, ES & NL

Mitochondrial Medicine Book Review:

Mitochondrial Medicine: A Primer for Health Care Providers and Translational Researchers is an applied, holistic resource that addresses the evolving and multidisciplinary area of mitochondrial disease. The book discusses the fundamentals of mitochondrial medicine in humans, as well as the pathophysiology, diagnosis and treatment of mitochondrial diseases. Three all-inclusive sections examine the role of mitochondria in common medical conditions, such as diabetes, heart failure and the full range of inherited mitochondrial diseases. Sections cover the genetic and biochemical basis of both mitochondrial DNA deletion syndromes and point mutation syndromes, their clinical presentation, treatment plans, genetic counseling, prenatal testing, and ongoing research. While providing a solid foundation in its topic area, each chapter in the book is written in an accessible format with illustrative case studies, thus making it a quick bedside or clinical laboratory reference. Includes a basic introduction to mitochondria and their misfunctions in human disease Presents current practice and research in mitochondrial medicine, with an emphasis on clinical presentation, diagnosis, treatment, genetic counseling and prenatal testing Features short, accessible chapters with illustrative case studies for quick reference Provides thorough coverage of inherited mitochondrial disorders, as well as the role of mitochondria in common medical conditions

Clinical Bioenergetics

Clinical Bioenergetics
Author: Sergej M. Ostojic
Publsiher: Academic Press
Total Pages: 716
Release: 2020-11-12
ISBN 10: 0128227729
ISBN 13: 9780128227725
Language: EN, FR, DE, ES & NL

Clinical Bioenergetics Book Review:

Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others. Provides a thorough discussion of foundational aspects of bioenergetics and disease, modes of analysis, and treatments for impaired bioenergetics Discusses the role of bioenergetics and treatment pathways in brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among other diseases and disorders Features chapter contributions from international leaders in translational bioenergetics research and clinical practice

Biochemistry and Experimental Biology

Biochemistry and Experimental Biology
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1977
ISBN 10:
ISBN 13: UCAL:B4297816
Language: EN, FR, DE, ES & NL

Biochemistry and Experimental Biology Book Review:

Pediatric Epilepsy Case Studies

Pediatric Epilepsy Case Studies
Author: Kevin Chapman,Jong M. Rho
Publsiher: CRC Press
Total Pages: 296
Release: 2008-09-18
ISBN 10: 1420083422
ISBN 13: 9781420083422
Language: EN, FR, DE, ES & NL

Pediatric Epilepsy Case Studies Book Review:

The amount of information currently available on pediatric epilepsy, as with all burgeoning fields, can seem overwhelming. Pediatric Epilepsy Case Studies: From Infancy and Childhood through Adolescence reviews the recent flood of new information on the pathophysiology, genetics, and treatment of the various epilepsy syndromes and distills it into an easy-to-use guide. Edited by respected and well-known leaders in the field, the book provides brief, but thorough, descriptions of the different syndromes commonly encountered in clinical practice across the pediatric range. Grasping the complexity and nuances associated with various epileptic syndromes can be daunting. Therefore, the book begins with an introduction to the fundamentals of epilepsy. Subsequent sections include succinct case presentations and clinically relevant discussions of the more common epilepsy syndromes affecting each age group. The chapter authors describe why they chose each particular case, what they learned, and how it changed their practice. The extensive resource section provides an authoritative guide to relevant findings scattered in the literature. Research in the field of epilepsy will continue at a rapid pace, with the ultimate hope of curing many intractable epilepsy syndromes. Organized chronologically, from neonate through adolescence, this book is the culmination of a group effort involving leading physicians and researchers whose contributions constitute a concise and practical reference for health professionals in training.

Case Studies in Pediatric Intensive Care

Case Studies in Pediatric Intensive Care
Author: Mark C. Rogers,Mark A. Helfaer
Publsiher: Unknown
Total Pages: 362
Release: 1993
ISBN 10:
ISBN 13: UOM:39015029878116
Language: EN, FR, DE, ES & NL

Case Studies in Pediatric Intensive Care Book Review:

This book has been compiled with two goals in mind. First, it is directed to physicians in training. The hope is to expose young doctors to the interesting breadth and complexity of the patients who present to the pediatric intensive care unit. This is directed at any level of training. Starting pediatric interns can be exposed to a far greater number of cases than they would encounter just by sequentially admitting their portion of the patients. Likewise, senior fellows will benefit from the experiences of a great number of PICUs around the world.

Comparative Kinetic Studies of Cytochrome C Reactions with Mitochondrial Redox Systems

Comparative Kinetic Studies of Cytochrome C Reactions with Mitochondrial Redox Systems
Author: Beverly Jean Errede
Publsiher: Unknown
Total Pages: 259
Release: 1976
ISBN 10:
ISBN 13: UCSD:31822011633229
Language: EN, FR, DE, ES & NL

Comparative Kinetic Studies of Cytochrome C Reactions with Mitochondrial Redox Systems Book Review:

International Journal of Fertility

International Journal of Fertility
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1972
ISBN 10:
ISBN 13: UCLA:31158000583806
Language: EN, FR, DE, ES & NL

International Journal of Fertility Book Review:

Most issues include Current bibliography index of mammalian reproduction.

Microbial Source Tracking Methods Applications and Case Studies

Microbial Source Tracking  Methods  Applications  and Case Studies
Author: Charles Hagedorn,Anicet R. Blanch,Valerie J. Harwood
Publsiher: Springer Science & Business Media
Total Pages: 642
Release: 2011-06-08
ISBN 10: 9781441993861
ISBN 13: 144199386X
Language: EN, FR, DE, ES & NL

Microbial Source Tracking Methods Applications and Case Studies Book Review:

Understanding the origin of fecal pollution is essential in assessing potential health risks as well as for determining the actions necessary to remediate the quality of waters contaminated by fecal matter. As a result, microbial source tracking (MST) has emerged as a field that has evolved and diversified rapidly since the first approaches were described only a decade ago. In response to the emergence of MST, there have been three large multi-laboratory method comparison studies (two in the US and one in Europe), plus numerous workshops, book chapters, and review articles dedicated to synthesizing information on the topic. Furthermore, a federal (USEPA) guide document describing the uses and limitations of MST methods was published in 2005, and a book dedicated to MST as an emerging issue in food safety was published in 2007. These documents provide a collective body of literature on MST that is both conflicting and complementary, often repetitious, and difficult to condense and interpret. In addition, it does not reflect the current diversity of MST approaches with different organisms, newer methodologies such as quantitative PCR, and anthropogenic chemicals, nor does it embrace the scope of MST research being conducted around the world. The three editors of the book, all with extensive MST expertise, have developed chapters and invited authors who reflect the rich diversity and truly international scope of MST. The unifying theme throughout the book is the design of more standardized approaches to MST that include performance criteria (regardless of method or organism), plus recommendations for field study design and MST implementation. The editors intend that this book will serve as a valuable reference for all those who are involved with

Journal of Medical Genetics

Journal of Medical Genetics
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1988
ISBN 10:
ISBN 13: OSU:32435018835157
Language: EN, FR, DE, ES & NL

Journal of Medical Genetics Book Review:

Biology of Reproduction

Biology of Reproduction
Author: Joseph Thomas Velardo
Publsiher: Unknown
Total Pages: 421
Release: 1972
ISBN 10:
ISBN 13: UIUC:30112111571979
Language: EN, FR, DE, ES & NL

Biology of Reproduction Book Review:

Achievements and Perspectives of Mitochondrial Research Biogenesis

Achievements and Perspectives of Mitochondrial Research  Biogenesis
Author: Ernesto Quagliariello
Publsiher: Elsevier Science & Technology
Total Pages: 482
Release: 1985
ISBN 10: 9780444807465
ISBN 13: 0444807462
Language: EN, FR, DE, ES & NL

Achievements and Perspectives of Mitochondrial Research Biogenesis Book Review:

Myology

Myology
Author: Andrew Engel,Betty Q. Banker
Publsiher: Unknown
Total Pages: 2186
Release: 1986
ISBN 10:
ISBN 13: UOM:39015011767798
Language: EN, FR, DE, ES & NL

Myology Book Review:

Studies on Mitochondrial Adenosine Triphosphatase

Studies on Mitochondrial Adenosine Triphosphatase
Author: Christine Carlsson-Skwirut
Publsiher: Unknown
Total Pages: 49
Release: 1982
ISBN 10:
ISBN 13: UCAL:B2714785
Language: EN, FR, DE, ES & NL

Studies on Mitochondrial Adenosine Triphosphatase Book Review:

Mitochondrial Pathology in Muscle Diseases

Mitochondrial Pathology in Muscle Diseases
Author: G. Scarlato
Publsiher: Unknown
Total Pages: 292
Release: 1983
ISBN 10:
ISBN 13: CHI:58838398
Language: EN, FR, DE, ES & NL

Mitochondrial Pathology in Muscle Diseases Book Review:

Belgian Journal of Zoology

Belgian Journal of Zoology
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2005
ISBN 10:
ISBN 13: UCSD:31822009545211
Language: EN, FR, DE, ES & NL

Belgian Journal of Zoology Book Review:

Molecular Tagging of Loci Conditioning Potyvirus Resistance and Mitochondrial Transmission Studies in Cucumber Cucumis Sativus L

Molecular Tagging of Loci Conditioning Potyvirus Resistance and Mitochondrial Transmission Studies in Cucumber  Cucumis Sativus L
Author: Young Hoon Park
Publsiher: Unknown
Total Pages: 184
Release: 2002
ISBN 10:
ISBN 13: WISC:89081050437
Language: EN, FR, DE, ES & NL

Molecular Tagging of Loci Conditioning Potyvirus Resistance and Mitochondrial Transmission Studies in Cucumber Cucumis Sativus L Book Review:

Mitochondrial Metabolism and Morphology in Mitochondrial Disease States

Mitochondrial Metabolism and Morphology in Mitochondrial Disease States
Author: Mariella Theresa Simon
Publsiher: Unknown
Total Pages: 277
Release: 2016
ISBN 10: 9781369688184
ISBN 13: 1369688180
Language: EN, FR, DE, ES & NL

Mitochondrial Metabolism and Morphology in Mitochondrial Disease States Book Review:

Mitochondria are the hub of cellular metabolism, respiration and energy production. They are sites of reactive oxidative species (ROS), heme and steroid generation. They buffer cellular calcium flux, regulate redox states, control cell cycle and death and are therefore at the nexus of human health and disease. Syndromes encountered in the mitochondrial disease clinic, associated with mutations in mitochondrial genes, are generally rare and require detailed clinical mitochondrial disease workups, including next generation sequencing technology. The discovery of new genes often presents itself with inconclusive findings, which need to be further pursued and delineated in the research setting. It is therefore of great importance to apply the "bedside to bench and back to bedside" principle in the field of mitochondrial medicine to advance diagnostic and treatment modalities. In this dissertation, I demonstrate bioenergetic findings in three novel mitochondrial disease genes, NARS2, TFAM and LonP1, in a collaborative effort. By doing so, I have helped to delineate the underlying cause of pathologies for families with mitochondrial disease. Presented are also two case studies of patients with mutations in POLG and GFM1, with unusual clinical findings, which may point to new, not yet described cellular processes associated with mitochondrial dysfunction. By correlating gene function with patient's disease, taking into consideration clinical parameters observed, I have also shown new metabolic findings in a primary fibroblast tissue culture system from patients with mutations in the mitochondrial matrix protease LonP1. The patients have mutations in a domain of the gene, which has never been associated with disease. Findings suggest that the patient phenotype depends on the location of the mutations in LonP1 and that clinical expression is domain specific. Findings also show increased susceptibility to stress, elicited by the use of antibiotic/antimycotic in the tissue culture system. In the future, I plan to build on the results from this study, to assess the effects of potential treatment modalities on mitochondrial function in fibroblast culture.