Mechanobiology

Mechanobiology
Author: Glen L. Niebur
Publsiher: Elsevier
Total Pages: 254
Release: 2019-12-01
ISBN 10: 0128179325
ISBN 13: 9780128179321
Language: EN, FR, DE, ES & NL

Mechanobiology Book Review:

Mechanobiology: From Molecular Sensing to Disease will provide a review of the current state of understanding of mechanobiology and its role in health and disease. It covers: Current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli, A review of diseases that with known or purported mechanobiological underpinnings; The role of mechanobiology in tissue engineering and regenerative medicine; Experimental methods to capture mechanobiological phenomena; Computational models in mechanobiology. Presents our current understanding of the main molecular pathways by which cells sense and respond to mechanical stimuli Provides a review of diseases with known or purported mechanobiological underpinnings Includes the role of mechanobiology in tissue engineering and regenerative medicine Covers experimental methods to capture mechanobiological phenomena

The Mathematics of Mechanobiology

The Mathematics of Mechanobiology
Author: Antonio DeSimone,Benoît Perthame,Alfio Quarteroni,Lev Truskinovsky
Publsiher: Springer Nature
Total Pages: 210
Release: 2020-06-29
ISBN 10: 3030451976
ISBN 13: 9783030451974
Language: EN, FR, DE, ES & NL

The Mathematics of Mechanobiology Book Review:

This book presents the state of the art in mathematical research on modelling the mechanics of biological systems – a science at the intersection between biology, mechanics and mathematics known as mechanobiology. The book gathers comprehensive surveys of the most significant areas of mechanobiology: cell motility and locomotion by shape control (Antonio DeSimone); models of cell motion and tissue growth (Benoît Perthame); numerical simulation of cardiac electromechanics (Alfio Quarteroni); and power-stroke-driven muscle contraction (Lev Truskinovsky). Each section is self-contained in terms of the biomechanical background, and the content is accessible to all readers with a basic understanding of differential equations and numerical analysis. The book disentangles the phenomenological complexity of the biomechanical problems, while at the same time addressing the mathematical complexity with invaluable clarity. The book is intended for a wide audience, in particular graduate students and applied mathematicians interested in entering this fascinating field.

Mechanobiology

Mechanobiology
Author: Simon Rawlinson
Publsiher: John Wiley & Sons
Total Pages: 432
Release: 2017-02-06
ISBN 10: 1118966147
ISBN 13: 9781118966143
Language: EN, FR, DE, ES & NL

Mechanobiology Book Review:

An emerging field at the interface of biology and engineering, mechanobiology explores the mechanisms by which cells sense and respond to mechanical signals—and holds great promise in one day unravelling the mysteries of cellular and extracellular matrix mechanics to cure a broad range of diseases. Mechanobiology: Exploitation for Medical Benefit presents a comprehensive overview of principles of mechanobiology, highlighting the extent to which biological tissues are exposed to the mechanical environment, demonstrating the importance of the mechanical environment in living systems, and critically reviewing the latest experimental procedures in this emerging field. Featuring contributions from several top experts in the field, chapters begin with an introduction to fundamental mechanobiological principles; and then proceed to explore the relationship of this extensive force in nature to tissues of musculoskeletal systems, heart and lung vasculature, the kidney glomerulus, and cutaneous tissues. Examples of some current experimental models are presented conveying relevant aspects of mechanobiology, highlighting emerging trends and promising avenues of research in the development of innovative therapies. Timely and important, Mechanobiology: Exploitation for Medical Benefit offers illuminating insights into an emerging field that has the potential to revolutionise our comprehension of appropriate cell biology and the future of biomedical research.

Mechanobiology Handbook Second Edition

Mechanobiology Handbook  Second Edition
Author: Jiro Nagatomi,Eno Essien Ebong
Publsiher: CRC Press
Total Pages: 682
Release: 2018-12-07
ISBN 10: 0429816731
ISBN 13: 9780429816734
Language: EN, FR, DE, ES & NL

Mechanobiology Handbook Second Edition Book Review:

This will be a substantial revision of a former reference work that willl now be developed as a primary text for emerging courses in mechanobiology/cell mechanics being offered in a growing number of biomedical engineering and chemical engineering departments worldwide. It will also serve as a professional reference book for engineers, scientisits and clinicians who are interested in mechanobiology, which is the study of the effects of mechanical environments on the biological processess of cells. The readers will gain a comprehensive review of recent research findings as well as elementary chapters on solid mechanics, fluide mechanics, and molecular analysis techniques.

Mechanobiology of Cell Cell and Cell Matrix Interactions

Mechanobiology of Cell Cell and Cell Matrix Interactions
Author: A. Wagoner Johnson,Brendan Harley
Publsiher: Springer Science & Business Media
Total Pages: 319
Release: 2011-02-21
ISBN 10: 9781441980830
ISBN 13: 1441980830
Language: EN, FR, DE, ES & NL

Mechanobiology of Cell Cell and Cell Matrix Interactions Book Review:

Mechanobiology of Cell-Matrix Interactions focuses on characterization and modeling of interactions between cells and their local extracellular environment, exploring how these interactions may mediate cell behavior. Studies of cell-matrix interactions rely on integrating engineering, (molecular and cellular) biology, and imaging disciplines. Recent advances in the field have begun to unravel our understanding of how cells gather information from their surrounding environment, and how they interrogate such information during the cell fate decision making process. Topics include adhesive and integrin-ligand interactions; extracellular influences on cell biology and behavior; cooperative mechanisms of cell-cell and cell-matrix interactions; the mechanobiology of pathological processes; (multi-scale) modeling approaches to describe the complexity or cell-matrix interactions; and quantitative methods required for such experimental and modeling studies.

Integrative Mechanobiology

Integrative Mechanobiology
Author: Yu Sun,Deok-Ho Kim,Craig A. Simmons
Publsiher: Cambridge University Press
Total Pages: 371
Release: 2015-11-12
ISBN 10: 1107078393
ISBN 13: 9781107078390
Language: EN, FR, DE, ES & NL

Integrative Mechanobiology Book Review:

Experts describe state-of-the-art micro-nano techniques for cell mechanobiology and introduce the most recent advances in the field.

Molecular and Cellular Mechanobiology

Molecular and Cellular Mechanobiology
Author: Shu Chien,Adam J. Engler,Peter Yingxiao Wang
Publsiher: Springer
Total Pages: 302
Release: 2016-08-10
ISBN 10: 1493956175
ISBN 13: 9781493956173
Language: EN, FR, DE, ES & NL

Molecular and Cellular Mechanobiology Book Review:

This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

Hemodynamics and Mechanobiology of Endothelium

Hemodynamics and Mechanobiology of Endothelium
Author: Tzung K. Hsiai,Brett Blackman,Hanjoong Jo
Publsiher: World Scientific
Total Pages: 370
Release: 2010
ISBN 10: 9814280410
ISBN 13: 9789814280419
Language: EN, FR, DE, ES & NL

Hemodynamics and Mechanobiology of Endothelium Book Review:

The book represents a paradigm shift from the traditional static model of investigation of oxidative biology to the dynamic model of vascular oxidative stress. The investigation of vascular biology and cardiovascular medicine is made possible by the use of tissue engineering, nanotechnology and stem cell research. This is the first textbook to target a wide readership from academia to industry and government agencies in the field of cardiovascular diseases.

Mechanobiology in Health and Disease

Mechanobiology in Health and Disease
Author: Stefaan Verbruggen
Publsiher: Academic Press
Total Pages: 527
Release: 2018-08-09
ISBN 10: 0128129530
ISBN 13: 9780128129531
Language: EN, FR, DE, ES & NL

Mechanobiology in Health and Disease Book Review:

Mechanobiology in Health and Disease brings together contributions from leading biologists, clinicians, physicists and engineers in one convenient volume, providing a unified source of information for researchers in this highly multidisciplinary area. Opening chapters provide essential background information on cell mechanotransduction and essential mechanobiology methods and techniques. Other sections focus on the study of mechanobiology in healthy systems, including bone, tendons, muscles, blood vessels, the heart and the skin, as well as mechanobiology studies of pregnancy. Final chapters address the nascent area of mechanobiology in disease, from the study of bone conditions, skin diseases and heart diseases to cancer. A discussion of future perspectives for research completes each chapter in the volume. This is a timely resource for both early-career and established researchers working on mechanobiology. Provides an essential digest of primary research from many fields and disciplines in one convenient volume Covers both experimental approaches and descriptions of mechanobiology problems from mathematical and numerical perspectives Addresses the hot topic of mechanobiology in disease, a particularly dynamic field of frontier science

Introduction to Cell Mechanics and Mechanobiology

Introduction to Cell Mechanics and Mechanobiology
Author: Christopher R. Jacobs,Hayden Huang,Ronald Y. Kwon
Publsiher: Garland Science
Total Pages: 350
Release: 2012-11-16
ISBN 10: 1135042659
ISBN 13: 9781135042653
Language: EN, FR, DE, ES & NL

Introduction to Cell Mechanics and Mechanobiology Book Review:

Introduction to Cell Mechanics and Mechanobiology is designed for a one-semester course in the mechanics of the cell offered to advanced undergraduate and graduate students in biomedical engineering, bioengineering, and mechanical engineering. It teaches a quantitative understanding of the way cells detect, modify, and respond to the physical prope

Mechanobiology

Mechanobiology
Author: J. F. Stoltz
Publsiher: IOS Press
Total Pages: 448
Release: 2004
ISBN 10: 9781586034368
ISBN 13: 1586034367
Language: EN, FR, DE, ES & NL

Mechanobiology Book Review:

Mechanobiology is now a vigorous branch of biomechanics and biorheology which is mainly concerned with the study of the influence of mechanical forces on cells and tissues and their clinical or therapeutical applications. As we are now at the age of proteomics and genomics and of cell micromechanical approaches, using methods like laser tweezers or confocal microscopy, mechanobiology brings new challenges. With these new researches, mechanobiology is the promise of new diagnostic and therapeutic approaches. The most recent work shows that the incidence of mechanical forces is specific to the system under scrutiny and that stresses are implicated in tissue physiology (for example by the production of the extracellular matrix), secretions (i.e. production of NO and prostaglandins by endothelial cells), or for the induction of specific functions via intercellular communication; hence the interest from pharmacology in studies on new molecules. Moreover, these new findings have led to the development of tissue engineering, which is the concept of substitute tissue developed in vitro, from bioresorbable or non-bioresorbable scaffolds and from cells harvested in a physiologic mechanical environment such as from cartilage, bone and vessels. At the same time, the problem of cell grafting in tissue repair and especially the use of stem cells have led to new therapeutic fields.

Lung The Developmental Morphogenesis Mechanobiology And Stem Cells

Lung  The  Developmental Morphogenesis  Mechanobiology  And Stem Cells
Author: Ahmed El-hashash,Eiman Abdel Meguid
Publsiher: World Scientific
Total Pages: 204
Release: 2019-01-29
ISBN 10: 9813277084
ISBN 13: 9789813277083
Language: EN, FR, DE, ES & NL

Lung The Developmental Morphogenesis Mechanobiology And Stem Cells Book Review:

With detailed scientific background and up-to-date research, this book examines recent developmental and cell biology, mechanobiology and stem cell biology discoveries to help provide a better understanding of lung development, repair and regeneration.Lung regeneration is an urgent therapeutic priority. The current major challenge is the generation of complex vascularized structures that can ultimately support or replace impaired lung function. Recent discoveries in biomedical engineering are analysed within the structural context of the lung to help provide a better understanding of the innovative solutions that could be used for restoring normal morphogenesis and regeneration of the lung. This also includes insights from basic developmental mechanisms of human lung development through the derivation and identification of stem cells, both from the early embryo as well as from differentiated organs and tissues.Suitable for a wide range of readers, including physicians and surgeons, scientists and researchers, and undergraduate and postgraduate students, this guide is an essential read for those working in the field of lung disease and development.

Mechanobiology Handbook Second Edition

Mechanobiology Handbook  Second Edition
Author: Jiro Nagatomi,Eno Essien Ebong
Publsiher: CRC Press
Total Pages: 682
Release: 2018-12-07
ISBN 10: 042981674X
ISBN 13: 9780429816741
Language: EN, FR, DE, ES & NL

Mechanobiology Handbook Second Edition Book Review:

Mechanobiology—the study of the effects of mechanics on biological events—has evolved to answer numerous research questions. Mechanobiology Handbook 2nd Edition is a reference book for engineers, scientists, and clinicians who are interested in mechanobiology and a textbook for senior undergraduate to graduate level students of this growing field. Readers will gain a comprehensive review of recent research findings as well as elementary chapters on solid mechanics, fluid mechanics, and molecular analysis techniques. The new edition presents, in addition to the chapters of the first edition, homework problem sets that are available online and reviews of research in uncovered areas. Moreover, the new edition includes chapters on statistical analysis, design of experiments and optical imaging. The editors of this book are researchers and educators in mechanobiology. They realized a need for a single volume to assist course instructors as a guide for didactic teaching of mechanobiology to a diverse student body. A mechanobiology course is frequently made up of both undergraduate and graduate students pursuing degrees in engineering, biology, or integrated engineering and biology. Their goal was to present both the elementary and cutting-edge aspects of mechanobiology in a manner that is accessible to students from many different academic levels and from various disciplinary backgrounds. Moreover, it is their hope that the readers of Mechanobiology Handbook 2nd Edition will find study questions at the end of each chapter useful for long-term learning and further discussion. Comprehensive collection of reviews of recent research Introductory materials in mechanics, biology, and statistics Discussion of pioneering and emerging mechanobiology concepts Presentation of cutting-edge mechanobiology research findings across various fields and organ systems End of chapter study questions, available online Considering the complexity of the mechanics and the biology of the human body, most of the world of mechanobiology remains to be studied. Since the field is still developing, the Mechanobiology Handbook raises many different viewpoints and approaches with the intention of stimulating further research endeavours.

Mechanobiology Handbook

Mechanobiology Handbook
Author: Jiro Nagatomi
Publsiher: CRC Press
Total Pages: 564
Release: 2011-03-15
ISBN 10: 1420091212
ISBN 13: 9781420091212
Language: EN, FR, DE, ES & NL

Mechanobiology Handbook Book Review:

Mechanobiology—the study of the effects of mechanical environments on the biological processes of cells—has evolved from traditional biomechanics via the incorporation of strong elements of molecular and cell biology. Currently, a broad range of organ systems are being studied by surgeons, physicians, basic scientists, and engineers. These mechanobiologists aim to create new therapies and further biological understanding by quantifying the mechanical environment of cells and the molecular mechanisms of mechanically induced pathological conditions. To achieve these goals, investigators must be familiar with both the basic concepts of mechanics and the modern tools of cellular/molecular biology. Unfortunately, current literature contains numerous studies that misuse standard mechanical estimations and terminology, or fail to implement appropriate molecular analyses. Therefore, the Mechanobiology Handbook not only presents cutting-edge research findings across various fields and organ systems, but also provides the elementary chapters on mechanics and molecular analysis techniques to encourage cross-field understanding and appropriate planning. Aided by the continuous advancement of research tools in both mechanics and biology, more sophisticated experiments and analyses are possible—thus fueling the growth of the field of mechanobiology. Considering the complexity of the mechanics and the biology of the human body, most of the world of biomechanics remains to be studied. Since the field is still developing, the Mechanobiology Handbook does not force one unified theory, but brings out many different viewpoints and approaches to stimulate further research questions.

Continuum Modeling in Mechanobiology

Continuum Modeling in Mechanobiology
Author: Larry A. Taber
Publsiher: Springer Nature
Total Pages: 535
Release: 2020-06-15
ISBN 10: 3030432092
ISBN 13: 9783030432096
Language: EN, FR, DE, ES & NL

Continuum Modeling in Mechanobiology Book Review:

This book examines key theoretical tools that are currently used to develop mathematical models as an aid in understanding the biological response of cells and tissues to mechanical stimuli. Problems in growth and remodeling, tissue and organ development, and functional adaptation are all covered. Chapters on tensor analysis and nonlinear elasticity provide the necessary background for understanding the engineering theories that are currently used to solve challenges in mechanobiology. This is an ideal book for biomechanical engineers who work on problems in mechanobiology and tissue engineering.

Basic Orthopaedic Biomechanics Mechano biology

Basic Orthopaedic Biomechanics   Mechano biology
Author: Van C. Mow,Rik Huiskes
Publsiher: Lippincott Williams & Wilkins
Total Pages: 720
Release: 2005
ISBN 10: 9780781739337
ISBN 13: 0781739330
Language: EN, FR, DE, ES & NL

Basic Orthopaedic Biomechanics Mechano biology Book Review:

Biomaterials / Ahmed El-Ghannam and Paul Ducheyne -- Biomechanics of the spine / Ian A. F. Stokes and James C. Iatridis -- Biomechanics of fracture fixation and fracture healing / Lutz E. Claes and Keita Ito -- Biomechanics and preclinical testing of artificial joints: the hip / Rik Huiskes and Jan Stolk -- Biomechanics of total knee replacement designs / Peter S. Walker.

Phylogenomic Approaches to Deal with Particularly Challenging Plant Lineages

Phylogenomic Approaches to Deal with Particularly Challenging Plant Lineages
Author: Marcial Escudero,Gonzalo Nieto Feliner,Lisa Pokorny,Daniel Spalink,Juan Viruel
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-01-08
ISBN 10: 2889663671
ISBN 13: 9782889663675
Language: EN, FR, DE, ES & NL

Phylogenomic Approaches to Deal with Particularly Challenging Plant Lineages Book Review:

Multiscale Modeling in Biomechanics and Mechanobiology

Multiscale Modeling in Biomechanics and Mechanobiology
Author: Suvranu De,Wonmuk Hwang,Ellen Kuhl
Publsiher: Springer
Total Pages: 286
Release: 2014-10-10
ISBN 10: 1447165993
ISBN 13: 9781447165996
Language: EN, FR, DE, ES & NL

Multiscale Modeling in Biomechanics and Mechanobiology Book Review:

Presenting a state-of-the-art overview of theoretical and computational models that link characteristic biomechanical phenomena, this book provides guidelines and examples for creating multiscale models in representative systems and organisms. It develops the reader's understanding of and intuition for multiscale phenomena in biomechanics and mechanobiology, and introduces a mathematical framework and computational techniques paramount to creating predictive multiscale models. Biomechanics involves the study of the interactions of physical forces with biological systems at all scales – including molecular, cellular, tissue and organ scales. The emerging field of mechanobiology focuses on the way that cells produce and respond to mechanical forces – bridging the science of mechanics with the disciplines of genetics and molecular biology. Linking disparate spatial and temporal scales using computational techniques is emerging as a key concept in investigating some of the complex problems underlying these disciplines. Providing an invaluable field manual for graduate students and researchers of theoretical and computational modelling in biology, this book is also intended for readers interested in biomedical engineering, applied mechanics and mathematical biology.

Vascular Mechanobiology in Physiology and Disease

Vascular Mechanobiology in Physiology and Disease
Author: Markus Hecker,Dirk J. Duncker
Publsiher: Springer Nature
Total Pages: 352
Release: 2021-03-10
ISBN 10: 3030631648
ISBN 13: 9783030631642
Language: EN, FR, DE, ES & NL

Vascular Mechanobiology in Physiology and Disease Book Review:

This volume of the series Cardiac and Vascular Biology presents the most relevant aspects of vascular mechanobiology along with many more facets of this fascinating, timely and clinically highly relevant field. Mechanotransduction, mechanosensing, fluid shear stress, hameodynamics and cell fate, are just a few topics to name. All important aspects of vascular mechanobiology in health and disease are reviewed by some of the top experts in the field. This volume, together with a second title on cardiac mechanobiology featured in this series, will be of high relevance to scientists and clinical researchers in the area of vascular biology, cardiology and biomedical engineering.

Modern Mechanobiology

Modern Mechanobiology
Author: Juhyun Lee,Sharon Gerecht,Hanjoong Jo,Tzung Hsiai
Publsiher: CRC Press
Total Pages: 262
Release: 2021-02-25
ISBN 10: 1000021262
ISBN 13: 9781000021264
Language: EN, FR, DE, ES & NL

Modern Mechanobiology Book Review:

Modern mechanobiology converges both engineering and medicine to address personalized medicine. This book is built on the previously well-received edition, Hemodynamics and Mechanobiology of Endothelium. The central theme is "omic" approaches to mechanosignal transduction underlying tissue development, injury, and repair. A cadre of investigators has contributed to the chapters, enriching the interface between mechanobiology and precision medicine for personalized diagnosis and intervention. The book begins with the fundamental basis of vascular disease in response to hemodynamic shear stress and then details cardiovascular development and regeneration, valvular and cardiac morphogenesis, mechanosensitive microRNA and histone unfolding, computational fluid dynamics, and light-sheet imaging. This edition represents a paradigm shift from traditional biomechanics and signal transduction to transgenic models, including novel zebrafish and chick embryos, and targets a wider readership from academia to industry and government agencies in the field of mechanobiology.