Lipid Signaling and Metabolism

Lipid Signaling and Metabolism
Author: James M. Ntambi
Publsiher: Academic Press
Total Pages: 566
Release: 2020-08-09
ISBN 10: 0128194057
ISBN 13: 9780128194058
Language: EN, FR, DE, ES & NL

Lipid Signaling and Metabolism Book Review:

Lipid Signaling and Metabolism provides foundational knowledge and methods to examine lipid metabolism and bioactive lipid signaling mediators that regulate a broad spectrum of biological processes and disease states. Here, world-renowned investigators offer a basic examination of general lipid, metabolism, intracellular lipid storage and utilization that is followed by an in-depth discussion of lipid signaling and metabolism across disease areas, including obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders. Throughout, authors demonstrate how expanding our understanding of lipid mediators in metabolism and signaling enables opportunities for novel therapeutics. Emphasis is placed on bioactive lipid metabolism and research that has been impacted by new technologies and their new potential to transform precision medicine. Provides a clear, up-to-date understanding of lipid signaling and metabolism and the impact of recent technologies critical to advancing new studies Empowers researchers to examine bioactive lipid signaling and metabolism, supporting translation to clinical care and precision medicine Discusses the role of lipid signaling and metabolism in obesity, diabetes, fatty liver disease, inflammation, cancer, cardiovascular disease and mood-related disorders, among others

Lipid Signaling in Plants

Lipid Signaling in Plants
Author: Teun Munnik
Publsiher: Springer Science & Business Media
Total Pages: 330
Release: 2009-12-03
ISBN 10: 9783642038730
ISBN 13: 3642038735
Language: EN, FR, DE, ES & NL

Lipid Signaling in Plants Book Review:

This comprehensive update on plant lipid signaling covers the measurement, regulation and function of phospholipases, lipid kinases, lipid phosphatases, inositolpolphosphates, polyphosphoinositides, phosphatic acid, and other lipid signals such as oxylipins.

Lipid Signaling in Human Diseases

Lipid Signaling in Human Diseases
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2020
ISBN 10: 9783030336691
ISBN 13: 3030336697
Language: EN, FR, DE, ES & NL

Lipid Signaling in Human Diseases Book Review:

Lipids are an integral part of cell membrane architecture, are intermediaries in cell metabolism, and are involved in transmitting cell signals from hormones, growth factors and nutrients. A number of lipases and phospholipases, lipid kinases, lipid phosphatases, sphingosine kinases, and their reaction products have been implicated in fundamental cellular processes including cell proliferation, division and migration. These enzymes and their products underlie the molecular mechanisms of numerous human diseases, in particular metabolic disease (diabetes), cancer, neurodegenerative disease and cardiovascular disease. Over the last decade, studies have advanced to the point that a number of inhibitors for these enzymes have been developed to attempt to ameliorate these conditions; some of the inhibitors are currently in human clinical trial. The need for this book is to review the current status of this field and the prospect for the inhibitors to be clinically important. .

Ageing Lessons from C elegans

Ageing  Lessons from C  elegans
Author: Anders Olsen,Matthew S. Gill
Publsiher: Springer
Total Pages: 439
Release: 2016-12-06
ISBN 10: 3319447033
ISBN 13: 9783319447032
Language: EN, FR, DE, ES & NL

Ageing Lessons from C elegans Book Review:

This book brings together in one volume the current state of ageing research in the nematode Caenorhabditis elegans. The authors are leading researchers in the field, placing this topic in the context of human ageing, describing how and why basic discoveries in this simple organism have impacted our prospects for intervention in the ageing process. The authors cover a broad range of topics with regards to organismal and reproductive ageing including anatomical, physiological and biochemical changes, as well as genetic and environmental interventions that promote longevity and ameliorate age-related disease. Ageing is the single most important factor determining the onset of human disease in developed countries. With current worldwide demographic trends indicating that the number of individuals over the age of 65 will continue to rise, it is clear that an understanding of the processes that underpin ageing and age-related disease represents a key challenge in the biomedical sciences. In recent years there have been huge advances in our understanding of the ageing process and many of these have stemmed from genetic analysis of C. elegans. With no analogous book in this subject area this work will be of interest to a wide audience, ranging from academic researchers to the general public.

Membrane Lipid Signaling in Aging and Age Related Disease

Membrane Lipid Signaling in Aging and Age Related Disease
Author: M.P. Mattson
Publsiher: Elsevier Science
Total Pages: 236
Release: 2003-05-20
ISBN 10: 9780444512970
ISBN 13: 0444512977
Language: EN, FR, DE, ES & NL

Membrane Lipid Signaling in Aging and Age Related Disease Book Review:

The lipids of cellular membranes not only serve roles in controlling the structure and fluidity of the membrane, but are increasingly recognized for their roles as signalling molecules and modifiers of membrane protein function. Recent studies described in this volume reveal striking changes in membrane lipids during aging and in age-related diseases such as cancer, cardiovascular disease and neurodegenerative disorders. Lipids including inositol phospholipids, cholesterol, sphingolipids and ceramides play important roles in signalling cellular responses to stress and specific stimuli such as growth factors, cytokines and neurotransmitters. One or more of these lipid mediators has been linked to the pathogenesis of age-related diseases. This book provides a comprehensive review of specific membrane lipid mediators and their roles in aging and age-related disease.

Lipid signaling in plants

Lipid signaling in plants
Author: Anonim
Publsiher: Frontiers E-books
Total Pages: 329
Release: 2021
ISBN 10: 2889191486
ISBN 13: 9782889191482
Language: EN, FR, DE, ES & NL

Lipid signaling in plants Book Review:

Biochemistry of Lipids Lipoproteins and Membranes

Biochemistry of Lipids  Lipoproteins and Membranes
Author: J.E. Vance,Dennis E. Vance
Publsiher: Elsevier
Total Pages: 595
Release: 1991-12-17
ISBN 10: 9780080860800
ISBN 13: 008086080X
Language: EN, FR, DE, ES & NL

Biochemistry of Lipids Lipoproteins and Membranes Book Review:

The second edition of this book on lipids, lipoprotein and membrane biochemistry has two major objectives - to provide an advanced textbook for students in these areas of biochemistry, and to summarise the field for scientists pursuing research in these and related fields. Since the first edition of this book was published in 1985 the emphasis on research in the area of lipid and membrane biochemistry has evolved in new directions. Consequently, the second edition has been modified to include four chapters on lipoproteins. Moreover, the other chapters have been extensively updated and revised so that additional material covering the areas of cell signalling by lipids, the assembly of lipids and proteins into membranes, and the increasing use of molecular biological techniques for research in the areas of lipid, lipoprotein and membrane biochemistry have been included. Each chapter of the textbook is written by an expert in the field, but the chapters are not simply reviews of current literature. Rather, they are written as current, readable summaries of these areas of research which should be readily understandable to students and researchers who have a basic knowledge of general biochemistry. The authors were selected for their abilities both as researchers and as communicators. In addition, the editors have carefully coordinated the chapters so that there is little overlap, yet extensive cross-referencing among chapters.

The Regulation of Membrane Lipid Metabolism Second Edition

The Regulation of Membrane Lipid Metabolism  Second Edition
Author: Guy A. Thompson, Jr.
Publsiher: CRC Press
Total Pages: 240
Release: 1992-03-10
ISBN 10: 9780849345616
ISBN 13: 0849345618
Language: EN, FR, DE, ES & NL

The Regulation of Membrane Lipid Metabolism Second Edition Book Review:

This book provides a concise description of the metabolic pathways by which lipids of animal and plant membranes are formed. The book emphasizes modulation of these pathways by hormones, diet, environmental stress, and other factors. This new edition is extensively revised, containing new material on topics such as lipid-mediated signal transduction and lipid-induced protein translocation. The new edition also features an entirely new chapter on lipids covalently bound to proteins. The book is excellent for all researchers and students interested in membrane lipid metabolism.

Lipid Signaling Protocols

Lipid Signaling Protocols
Author: Banafshé Larijani,Rudiger Woscholski,Colin A. Rosser
Publsiher: Humana Press
Total Pages: 429
Release: 2008-11-11
ISBN 10: 9781588297273
ISBN 13: 1588297276
Language: EN, FR, DE, ES & NL

Lipid Signaling Protocols Book Review:

Lipid Signaling Protocols assembles in a single volume the various tools and methodologies needed by the interested investigator to unravel lipid dependent signaling and cell function. Divided into two convenient sections, the volume begins by summarizing the physical properties of hydrophobic metabolites as well as the physical methodologies used for their analysis, which leads to the second section and its selection of biological methods, focused around the most relevant lipids, their corresponding metabolizing enzymes and the recognition proteins. Following the highly successful Methods in Molecular BiologyTM series format, the chapters provide readily reproducible laboratory protocols, lists of necessary materials and reagents, and the tips on troubleshooting and avoiding known pitfalls. Contributed to by top researchers in the field, Lipid Signaling Protocols is an essential resource for both experienced and novice researchers who desire a better understanding of the application of physical methodologies in the context of lipid signaling and lipid metabolism in cell biology.

Lipid metabolism in mammals

Lipid metabolism in mammals
Author: Fred Snyder
Publsiher: Springer Science & Business Media
Total Pages: 329
Release: 2012-12-06
ISBN 10: 1468428322
ISBN 13: 9781468428322
Language: EN, FR, DE, ES & NL

Lipid metabolism in mammals Book Review:

During the past decade we have witnessed a vast expansion in our knowl edge of lipid metabolism, especially for mammalian tissues. One obvious conclusion arising from these studies is that no single overall scheme of lipid metabolism can be classed as distinctly characteristic of all mamma lian organs. Although certain synthetic and degradative lipid pathways are similar in a variety of organs, I have been impressed by the notable exceptions. I was motivated to organize this work on Lipid Metabolism in Mammals because of the lack of a single reference source containing a comparative organ approach to lipid metabolism in mammals that empha sizes the uniqueness of pathways in the various organs of the body. Because of the escalation in lipid research, I also feel strongly that there is an urgent need for an updated concise account of this field. The group of authors for the chapters in the two volumes of Lipid Metabolism in Mammals were selected for their expertise and personal experience with the lipid metabolism of the organs or blood constituents that are the subjects of the chapters. Sufficient leeway has been given each author to approach the subject matter from a personal viewpoint. How ever, the overall direction of each chapter has been slanted to emphasize the similarities and differences in lipid metabolism among organ systems. The introductory chapter on general pathways provides a convenient refer ence to illustrations of specific reaction sequences that are well established and that occur in a number of organs.

Biochemistry of Lipids Lipoproteins and Membranes

Biochemistry of Lipids  Lipoproteins and Membranes
Author: Neale Ridgway,Roger McLeod
Publsiher: Elsevier
Total Pages: 612
Release: 2015-07-24
ISBN 10: 0444634495
ISBN 13: 9780444634498
Language: EN, FR, DE, ES & NL

Biochemistry of Lipids Lipoproteins and Membranes Book Review:

Biochemistry of Lipids: Lipoproteins and Membranes, Volume Six, contains concise chapters that cover a wide spectrum of topics in the field of lipid biochemistry and cell biology. It provides an important bridge between broad-based biochemistry textbooks and more technical research publications, offering cohesive, foundational information. It is a valuable tool for advanced graduate students and researchers who are interested in exploring lipid biology in more detail, and includes overviews of lipid biology in both prokaryotes and eukaryotes, while also providing fundamental background on the subsequent descriptions of fatty acid synthesis, desaturation and elongation, and the pathways that lead the synthesis of complex phospholipids, sphingolipids, and their structural variants. Also covered are sections on how bioactive lipids are involved in cell signaling with an emphasis on disease implications and pathological consequences. Serves as a general reference book for scientists studying lipids, lipoproteins and membranes and as an advanced and up-to-date textbook for teachers and students who are familiar with the basic concepts of lipid biochemistry References from current literature will be included in each chapter to facilitate more in-depth study Key concepts are supported by figures and models to improve reader understanding Chapters provide historical perspective and current analysis of each topic

Stearoyl CoA Desaturase Genes in Lipid Metabolism

Stearoyl CoA Desaturase Genes in Lipid Metabolism
Author: James M. Ntambi, Ph.D.
Publsiher: Springer Science & Business Media
Total Pages: 239
Release: 2013-08-15
ISBN 10: 146147969X
ISBN 13: 9781461479697
Language: EN, FR, DE, ES & NL

Stearoyl CoA Desaturase Genes in Lipid Metabolism Book Review:

Obesity and diabetes develop as a complex result of genetic, metabolic and environmental factors and are characterized by increased lipogenesis and lipid accumulation in many tissues. Stearoyl-CoA desaturase (SCD) genes are a critical regulator of lipogenesis and catalyzes the synthesis of monounsaturated fatty acids (MUFA), mainly oleoyl- (18:1n9) and palmitoleoyl-CoA (16:1n7). These MUFAs are the major fatty acid substrates for the synthesis of triglycerides, cholesterol esters, wax esters and membrane phospholipids. There are 4 SCD isoforms (SCD1-4) in mice and two (hSCD1 and hSCD5) expressed in humans. At first glance, stearoyl-CoA desaturase enzyme would be considered a housekeeping enzyme because it synthesizes oleate a well-known fatty acid that is abundant in many dietary sources. However numerous studies have shown that SCD is a very highly regulated enzyme that features in so many physiological processes ranging from fat differentiation, carbohydrate and fat metabolism, inflammation and cancer. The editor’s studies using stearoyl-CoA desaturase knockout (SCD1-/-) mice and studies of other investigators using pharmacological approaches to reduce SCD1 expression in mouse tissues have all established that the expression of SCD1 gene isoform represents a key step in partitioning of lipids between storage and oxidation. High SCD expression favors fat storage leading to obesity while reduced SCD expression favors fat burning and leanness. Although these studies clearly illustrated that SCD1 expression is involved in the development of obesity and insulin resistance, questions remain in the elucidation of the mechanisms involved and role of SCD1. This book includes chapters by leading researchers on SCD Genes in the brain, heart, muscle, liver metabolism, Colitis, and more. ​

Lipid Mediated Signaling

Lipid Mediated Signaling
Author: Eric J. Murphy,Eric Murphy,Thad Rosenberger,Thad A. Rosenberger
Publsiher: CRC Press
Total Pages: 452
Release: 2010-03-05
ISBN 10: 9780849381423
ISBN 13: 0849381428
Language: EN, FR, DE, ES & NL

Lipid Mediated Signaling Book Review:

As the highly anticipated update to Lipid Second Messengers (CRC Press, 1999), Lipid-Mediating Signaling is a current and comprehensive overview of research methods used in lipid-mediated signal transduction. Pioneering experts provide a much-needed distillation of a decade’s worth of advances in research techniques that are pertinent in understanding how lipid-mediated signal transduction ties to pathologic disorders. Part I describes methods used to identify activities of and assay the expression of different enzymes involved in lipid-mediated signaling. Part II highlights the use of mass spectrometry to ascertain the lipid content in various systems. Part III contains two chapters devoted to techniques used to determine the role of lipids in the activation of gene transcription. Part IV rounds out the book’s solid coverage by focusing on methods used to assess fatty acid uptake and metabolism. Lipid-Mediating Signaling is an unrivaled reference for this rapidly expanding, yet resource-limited field, and it is a valuable resource for for cell biologists, biochemists, and pharmacologists, as well as for researchers studying signaling transduction.

Understanding Lipid Metabolism with Microarrays and Other Omic Approaches

Understanding Lipid Metabolism with Microarrays and Other Omic Approaches
Author: Alvin Berger,Matthew A. Roberts
Publsiher: CRC Press
Total Pages: 472
Release: 2004-11-30
ISBN 10: 9781420030921
ISBN 13: 1420030922
Language: EN, FR, DE, ES & NL

Understanding Lipid Metabolism with Microarrays and Other Omic Approaches Book Review:

Reviewing current studies and previously unpublished research from leading laboratories around the world, Unraveling Lipid Metabolism with Microarrays demonstrates the use of microarrays and transcriptomic approaches to clarify the biological function of lipids. With contributions from world-class researchers, the book focuses on the use of microar

Druggable Lipid Signaling Pathways

Druggable Lipid Signaling Pathways
Author: Yasuyuki Kihara
Publsiher: Springer Nature
Total Pages: 329
Release: 2021
ISBN 10: 3030506215
ISBN 13: 9783030506216
Language: EN, FR, DE, ES & NL

Druggable Lipid Signaling Pathways Book Review:

Membrane Microdomain Signaling

Membrane Microdomain Signaling
Author: Mark P. Mattson
Publsiher: Springer Science & Business Media
Total Pages: 214
Release: 2007-10-27
ISBN 10: 159259803X
ISBN 13: 9781592598038
Language: EN, FR, DE, ES & NL

Membrane Microdomain Signaling Book Review:

Cutting-edge articles review our current understanding of lipid microdomain signaling mechanisms and their physiological and pathological importance. The book describes the role of lipid rafts in learning, memory, and cancer, presents the emerging evidence that lipid rafts play critical roles in signaling pathways and the regulation of synaptic function in the nervous system, and shows how alterations in lipid raft metabolism are implicated in the pathogenesis of neurodegenerative disorders. Techniques are also described for the isolation of lipid rafts, the analysis of the lipid and protein components of lipid rafts, the imaging of lipid rafts in living cells, and the analysis of signal transduction in lipid rafts.

The Molecular Nutrition of Fats

The Molecular Nutrition of Fats
Author: Vinood B. Patel
Publsiher: Academic Press
Total Pages: 470
Release: 2018-10-29
ISBN 10: 0128112980
ISBN 13: 9780128112984
Language: EN, FR, DE, ES & NL

The Molecular Nutrition of Fats Book Review:

The Molecular Nutrition of Fats presents the nutritional and molecular aspects of fats by assessing their dietary components, their structural and metabolic effects on the cell, and their role in health and disease. Subject areas include molecular mechanisms, membranes, polymorphisms, SNPs, genomic wide analysis, genotypes, gene expression, genetic modifications and other aspects. The book is divided into three sections, providing information on the general and introductory aspects, the molecular biology of the cell, and the genetic machinery and its function. Topics discussed include lipid-related molecules, dietary lipids and lipid metabolism, high fat diets, choline, cholesterol, membranes, trans-and saturated fatty acids, and lipid rafts. Other sections provide comprehensive discussions on G protein-coupled receptors, micro RNA, transcriptomics, transcriptional factors, cholesterol, triacylglycerols, beta-oxidation, cholesteryl ester transfer, beta-oxidation, lysosomes, lipid droplets, insulin mTOR signaling and ligands, and more. Summarizes molecular nutrition in health as related to fats Discusses the impact of fats on cancer, heart disease, dementia, and respiratory and intestinal disease Includes preclinical, clinical and population studies Covers the genome, the whole body and whole communities Includes key facts, a mini dictionary of terms and summary points

Hypoxia and Human Diseases

Hypoxia and Human Diseases
Author: Jing Zheng,Chi Zhou
Publsiher: BoD – Books on Demand
Total Pages: 454
Release: 2017-02-01
ISBN 10: 9535128957
ISBN 13: 9789535128953
Language: EN, FR, DE, ES & NL

Hypoxia and Human Diseases Book Review:

This book contains a total of 21 chapters, each of which was written by experts in the corresponding field. The objective of this book is to provide a comprehensive and updated overview of cellular and molecular mechanisms underlying hypoxia's impacts on human health, as well as current advances and future directions in the detection, recognition, and management of hypoxia-related disorders. This collection of articles provides a clear update in the area of hypoxia research for biomedical researchers, medical students, nurse practitioners, and practicing clinicians in the fields of high altitude biology, cardiovascular biology and medicine, tumor oncology, obstetrics, pediatrics, and orthodontics and for others who may be interested in hypoxia.

Lipids in Plant and Algae Development

Lipids in Plant and Algae Development
Author: Yuki Nakamura,Yonghua Li-Beisson
Publsiher: Springer
Total Pages: 533
Release: 2016-03-29
ISBN 10: 3319259792
ISBN 13: 9783319259796
Language: EN, FR, DE, ES & NL

Lipids in Plant and Algae Development Book Review:

This book summarizes recent advances in understanding the functions of plant and algal lipids in photosynthesis, in development and signaling, and in industrial applications. As readers will discover, biochemistry, enzymology and analytical chemistry, as well as gene knock-out studies have all contributed to our rapidly increasing understanding of the functions of lipids. In the past few decades, distinct physical and biochemical properties of specific lipid classes were revealed in plant and algal lipids and the functional aspects of lipids in modulating critical biological processes have been uncovered. These chapters from international authors across relevant research fields highlight the underlying evolutionary context of lipid function in photosynthetic unicellular and multicellular organisms. The book goes on to encompass what lipids can do for industrial applications at a time of fascination with plants and algae in carbon fixation and as sources for production of food, energy and novel chemicals. The developmental context is a part of the fresh and engaging perspective that is presented in this work which graduate students and scientists will find both illuminating and useful.

Lipid Metabolism in Signaling Systems

Lipid Metabolism in Signaling Systems
Author: John N. Fain
Publsiher: Unknown
Total Pages: 357
Release: 1993
ISBN 10:
ISBN 13: UVA:X002428430
Language: EN, FR, DE, ES & NL

Lipid Metabolism in Signaling Systems Book Review:

Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume. Major topics covered include: * Techniques for examining the role of phosphoinositides in signal transduction * Techniques related to protein kinase C * Analysis of inositol phosphates * Techniques to analyze phospholipid turnover in the brain