Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry

Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry
Author: Bindesh Shrestha
Publsiher: Elsevier
Total Pages: 300
Release: 2020-11-15
ISBN 10: 9780128189986
ISBN 13: 0128189983
Language: EN, FR, DE, ES & NL

Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry Book Review:

Introduction to Spatial Mapping of Biomolecules by Imaging Mass Spectrometry introduces scientists to IMS, describing its many applications for diverse classes of biomolecules. The book is divided into two sections, with the first building a foundation of IMS knowledge by introducing sample preparation, visualization guidelines, molecule identification, quantification, and software and hardware tools. The second section contains chapters focused on each biomolecule class (sugars, polar metabolites, and so on). All chapters include an introduction/background, review of complementary non-IMS techniques, a summary of successful IMS case studies with illustrative figures, a table (showing tissue, condition, ionization modality, and more), and future directions. The second part of the book can be used by both novices and experts looking for a quick deep-dive into IMS for a specific class of molecule used in their research. Provides the introductory foundations of Imaging Mass Spectrometry for those new to the technique Organized by molecule class to facilitate a quick, deep-dive, allowing researchers to immediately apply these techniques to their work Includes a table in every molecule class chapter, summarizing the IMS experiments done for each class of molecules

Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism

Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism
Author: Joseph Banoub
Publsiher: Springer
Total Pages: 291
Release: 2014-11-03
ISBN 10: 9401792380
ISBN 13: 9789401792387
Language: EN, FR, DE, ES & NL

Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism Book Review:

This NATO-ASI installment is designed to provide an advanced overview for doctoral and post-doctoral candidates of the state-of-the-art technologies for bio-detection. The main objective of the work aims at providing readers with the latest developments necessary to successfully understand the CBRN Agents and their associated biotechnologies. The core methods focused on are mass spectrometry (including chromatographic and electrophoretic separation) and comparisons to spectroscopic, immunological and molecular analysis of chemical, biological and nuclear agents.

Biocomputing 2007

Biocomputing 2007
Author: Anonim
Publsiher: World Scientific
Total Pages: 507
Release: 2006-12-11
ISBN 10: 9812704175
ISBN 13: 9789812704177
Language: EN, FR, DE, ES & NL

Biocomputing 2007 Book Review:

The Pacific Symposium on Biocomputing (PSB) 2007 is an international, multidisciplinary conference for the presentation and discussion of current research in the theory and application of computational methods in problems of biological significance. Presentations are rigorously peer reviewed and are published in an archival proceedings volume. PSB 2007 will be held January 3-7, 2007 at the Grand Wailea, Maui. Tutorials will be offered prior to the start of the conference.PSB 2007 will bring together top researchers from the US, the Asian Pacific nations, and around the world to exchange research results and address open issues in all aspects of computational biology. It is a forum for the presentation of work in databases, algorithms, interfaces, visualization, modeling, and other computational methods, as applied to biological problems, with emphasis on applications in data-rich areas of molecular biology.The PSB has been designed to be responsive to the need for critical mass in sub-disciplines within biocomputing. For that reason, it is the only meeting whose sessions are defined dynamically each year in response to specific proposals. PSB sessions are organized by leaders of research in biocomputing's “hot topics.” In this way, the meeting provides an early forum for serious examination of emerging methods and approaches in this rapidly changing field.

Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry

Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry
Author: Susmita Datta,Bart J. A. Mertens
Publsiher: Springer
Total Pages: 295
Release: 2016-12-15
ISBN 10: 3319458094
ISBN 13: 9783319458090
Language: EN, FR, DE, ES & NL

Statistical Analysis of Proteomics, Metabolomics, and Lipidomics Data Using Mass Spectrometry Book Review:

This book presents an overview of computational and statistical design and analysis of mass spectrometry-based proteomics, metabolomics, and lipidomics data. This contributed volume provides an introduction to the special aspects of statistical design and analysis with mass spectrometry data for the new omic sciences. The text discusses common aspects of design and analysis between and across all (or most) forms of mass spectrometry, while also providing special examples of application with the most common forms of mass spectrometry. Also covered are applications of computational mass spectrometry not only in clinical study but also in the interpretation of omics data in plant biology studies. Omics research fields are expected to revolutionize biomolecular research by the ability to simultaneously profile many compounds within either patient blood, urine, tissue, or other biological samples. Mass spectrometry is one of the key analytical techniques used in these new omic sciences. Liquid chromatography mass spectrometry, time-of-flight data, and Fourier transform mass spectrometry are but a selection of the measurement platforms available to the modern analyst. Thus in practical proteomics or metabolomics, researchers will not only be confronted with new high dimensional data types—as opposed to the familiar data structures in more classical genomics—but also with great variation between distinct types of mass spectral measurements derived from different platforms, which may complicate analyses, comparison, and interpretation of results.

Mass Spectrometry Imaging in Food Analysis

Mass Spectrometry Imaging in Food Analysis
Author: Leo M.L. Nollet
Publsiher: CRC Press
Total Pages: 198
Release: 2020-04-29
ISBN 10: 0429765304
ISBN 13: 9780429765308
Language: EN, FR, DE, ES & NL

Mass Spectrometry Imaging in Food Analysis Book Review:

Food contains various compounds and many technologies exist to analyze those molecules of interest. However, the analysis of the spatial distribution of those compounds using conventional technology, such as liquid chromatography-mass spectrometry or gas chromatography-mass spectrometry is difficult. Mass spectrometry imaging (MSI) is a mass spectrometry technique to visualize the spatial distribution of molecules, as biomarkers, metabolites, peptides or proteins by their molecular masses. Despite the fact that MSI has been generally considered a qualitative method, the signal generated by this technique is proportional to the relative abundance of the analyte and so quantification is possible. Mass Spectrometry Imaging in Food Analysis, a volume in the Food Analysis and Properties Series, explains how the novel use of matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) will be an ideal complementary approach. MALDI-MSI is a two-dimensional MALDI-MS technology that can detect compounds in a tissue section without extraction, purification, separation, or labeling. It can be used to visualize the spatial distribution of biomolecules in foods. Features: Explains the novel use of matrix-assisted laser desorption/ionization mass spectrometry imaging in food analysis Describes how MALDI-MSI will be a useful technique for optical quality assurance. Shows how MALDI-MSI detects food contaminants and residues Covers the historical development of the technology While there are a multitude of books on mass spectrometry, none focus on food applications and thus this book is ideally suited to food scientists, food industry personnel engaged in product development, research institutions, and universities active in food analysis or chemical analysis. Also available in the Food Analysis and Properties Series: Food Aroma Evolution: During Food Processing, Cooking, and Aging, edited by Matteo Bordiga and Leo M.L. Nollet (ISBN: 9781138338241) Ambient Mass Spectroscopy Techniques in Food and the Environment, edited by Leo M.L. Nollet and Basil K. Munjanja (ISBN: 9781138505568) Hyperspectral Imaging Analysis and Applications for Food Quality, edited by N.C. Basantia, Leo M.L. Nollet, and Mohammed Kamruzzaman (ISBN: 9781138630796) For a complete list of books in this series, please visit our website at: www.crcpress.com/Food-Analysis--Properties/book-series/CRCFOODANPRO

Advances in Imaging and Electron Physics

Advances in Imaging and Electron Physics
Author: Anonim
Publsiher: Academic Press
Total Pages: 440
Release: 2012-12-31
ISBN 10: 0123946352
ISBN 13: 9780123946355
Language: EN, FR, DE, ES & NL

Advances in Imaging and Electron Physics Book Review:

Advances in Imaging and Electron Physics merges two long-running serials--Advances in Electronics and Electron Physics and Advances in Optical and Electron Microscopy. This series features extended articles on the physics of electron devices (especially semiconductor devices), particle optics at high and low energies, microlithography, image science and digital image processing, electromagnetic wave propagation, electron microscopy, and the computing methods used in all these domains. Contributions from leading authorities Informs and updates on all the latest developments in the field

Pacific Symposium on Biocomputing

Pacific Symposium on Biocomputing
Author: Anonim
Publsiher: Anonim
Total Pages: 329
Release: 2007
ISBN 10:
ISBN 13: UOM:39015069292194
Language: EN, FR, DE, ES & NL

Pacific Symposium on Biocomputing Book Review:

Advanced Mass Spectrometry for Food Safety and Quality

Advanced Mass Spectrometry for Food Safety and Quality
Author: Anonim
Publsiher: Elsevier
Total Pages: 734
Release: 2015-05-08
ISBN 10: 0444633928
ISBN 13: 9780444633927
Language: EN, FR, DE, ES & NL

Advanced Mass Spectrometry for Food Safety and Quality Book Review:

Advanced Mass Spectrometry for Food Safety and Quality provides information on recent advancements made in mass spectrometry-based techniques and their applications in food safety and quality, also covering the major challenges associated with implementing these technologies for more effective identification of unknown compounds, food profiling, or candidate biomarker discovery. Recent advances in mass spectrometry technologies have uncovered tremendous opportunities for a range of food-related applications. However, the distinctive characteristics of food, such as the wide range of the different components and their extreme complexity present enormous challenges. This text brings together the most recent data on the topic, providing an important resource towards greater food safety and quality. Presents critical applications for a sustainable, affordable and safe food supply Covers emerging problems in food safety and quality with many specific examples. Encompasses the characteristics, advantages, and limitations of mass spectrometry, and the current strategies in method development and validation Provides the most recent data on the important topic of food safety and quality

Introduction to Protein Mass Spectrometry

Introduction to Protein Mass Spectrometry
Author: Pradip Kumar Ghosh
Publsiher: Academic Press
Total Pages: 312
Release: 2015-12-10
ISBN 10: 0128021128
ISBN 13: 9780128021125
Language: EN, FR, DE, ES & NL

Introduction to Protein Mass Spectrometry Book Review:

Introduction to Protein Mass Spectrometry provides a comprehensive overview of this increasingly important, yet complex, analytical technique. Unlike many other methods which automatically yield an absolutely unique protein name as output, protein mass spectrometry generally requires a deduction of protein identity from determination of peptide fragmentation products. This book enables readers to both understand, and appreciate, how determinations about protein identity from mass spectrometric data are made. Coverage begins with the technical basics, including preparations, instruments, and spectrometric analysis of peptides and proteins, before exploring applied use in biological applications, bioinformatics, database, and software resources. Citing the most recent and relevant work in the field of biological mass spectrometry, the book is written for researchers and scientists new to the field, but is also an ideal resource for those hoping to hone their analytical abilities. Offers introductory information for scientists and researchers new to the field, as well as advanced insight into the critical assessment of computer-analyzed mass spectrometric results and their current limitations Provides examples of commonly-used MS instruments from Bruker, Applied Biosystems, JEOL, Thermo Scientific/Thermo Fisher Scientific, IU, and Waters Includes biological applications and exploration of analytical tools and databases for bioinformatics

ToF-SIMS

ToF-SIMS
Author: J. C. Vickerman,David Briggs
Publsiher: IM Publications
Total Pages: 732
Release: 2013
ISBN 10: 1906715173
ISBN 13: 9781906715175
Language: EN, FR, DE, ES & NL

ToF-SIMS Book Review:

Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is the most versatile of the surface analysis techniques that have been developed during the last 30 years. This is the Second Edition of the first book ToF-SIMS: Surface analysis by Mass Spectrometry to be dedicated to the subject and the treatment is comprehensive

Applications of Mass Spectrometry Imaging to Cancer

Applications of Mass Spectrometry Imaging to Cancer
Author: Anonim
Publsiher: Academic Press
Total Pages: 312
Release: 2017-01-19
ISBN 10: 0128054409
ISBN 13: 9780128054406
Language: EN, FR, DE, ES & NL

Applications of Mass Spectrometry Imaging to Cancer Book Review:

Applications of Mass Spectrometry Imaging to Cancer, the latest volume in the Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on applications of mass spectrometry imaging to cancer. Provides information on cancer research Offers outstanding and original reviews on a range of cancer research topics Serves as an indispensable reference for researchers and students alike

Lipid Analysis

Lipid Analysis
Author: W. W. Christie,X Han
Publsiher: Elsevier
Total Pages: 448
Release: 2010-01-10
ISBN 10: 0857097865
ISBN 13: 9780857097866
Language: EN, FR, DE, ES & NL

Lipid Analysis Book Review:

This well-known and highly successful book was first published in 1973 and has been completely re-written in subsequent editions (published in 1982 and 2003). This new Fourth Edition has become necessary because of the pace of developments in mass spectrometry of intact lipids, which has given recognition of lipid analysis and ‘lipidomics’ as a distinct science. To bring the book up to date with these developments, author William W. Christie is joined by co-author Xianlin Han. Although devoting considerable space to mass spectrometry and lipidomics, Lipid analysis remains a practical guide, in one volume, to the complexities of the analysis of lipids. As in past editions, it is designed to act as a primary source, of value at the laboratory bench rather than residing on a library shelf. Lipid analysis deals with the isolation, separation, identification and structural analysis of glycerolipids, including triacylglycerols, phospholipids, sphingolipids, and the various hydrolysis products of these. The chapters follow a logical sequence from the extraction of lipids to the isolation and characterization of particular lipid classes and of molecular species of each, and to the mass spectrometric analysis of lipids and lipidomics. The new influence of mass spectrometry is due mainly to the development of electrospray ionization (ESI) and matrix-assisted laser desorption/ionization (MALDI). Most emphasis in this book is placed on ESI, which is enabling structural characterization of different lipid classes and the identification of novel lipids and their molecular species.

Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry

Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry
Author: Rainer Cramer
Publsiher: Springer
Total Pages: 286
Release: 2015-11-09
ISBN 10: 3319048198
ISBN 13: 9783319048192
Language: EN, FR, DE, ES & NL

Advances in MALDI and Laser-Induced Soft Ionization Mass Spectrometry Book Review:

This book covers the state-of-the-art of modern MALDI (matrix-assisted laser desorption/ionization) and its applications. New applications and improvements in the MALDI field such as biotyping, clinical diagnosis, forensic imaging, and ESI-like ion production are covered in detail. Additional topics include MS imaging, biotyping/speciation and large-scale, high-speed MS sample profiling, new methods based on MALDI or MALDI-like sample preparations, and the advantages of ESI to MALDI MS analysis. This is an ideal book for graduate students and researchers in the field of bioanalytical sciences. This book also: • Showcases new techniques and applications in MALDI MS • Demonstrates how MALDI is preferable to ESI (electrospray ionization) • Illustrates the pros and cons associated with biomarker discovery studies in clinical proteomics and the various application areas, such as cancer proteomics

Molecular Biology of the Cell

Molecular Biology of the Cell
Author: Bruce Alberts
Publsiher: Anonim
Total Pages: 329
Release: 2004
ISBN 10: 9780815332183
ISBN 13: 0815332181
Language: EN, FR, DE, ES & NL

Molecular Biology of the Cell Book Review:

Fundamentals and Applications of Fourier Transform Mass Spectrometry

Fundamentals and Applications of Fourier Transform Mass Spectrometry
Author: Philippe Schmitt-Kopplin,Basem Kanawati
Publsiher: Elsevier
Total Pages: 778
Release: 2019-08-11
ISBN 10: 0128140143
ISBN 13: 9780128140147
Language: EN, FR, DE, ES & NL

Fundamentals and Applications of Fourier Transform Mass Spectrometry Book Review:

Fundamentals and Applications of Fourier Transform Mass Spectrometry is the first book to delve into the underlying principles on the topic and their linkage to industrial applications. Drs. Schmitt-Kopplin and Kanawati have brought together a team of leading experts in their respective fields to present this technique from many different perspectives, describing, at length, the pros and cons of FT-ICR and Orbitrap. Numerous examples help researchers decide which instruments to use for their particular scientific problem and which data analysis methods should be applied to get the most out of their data. Covers FT-ICR-MS and Orbitrap’s fundamentals, enhancing researcher knowledge Includes details on ion sources, data processing, chemical analysis and imaging Provides examples across the wide spectrum of applications, including omics, environmental, chemical, pharmaceutical and food analysis

Proteomic and Metabolomic Approaches to Biomarker Discovery

Proteomic and Metabolomic Approaches to Biomarker Discovery
Author: Haleem J. Issaq,Timothy D. Veenstra
Publsiher: Academic Press
Total Pages: 504
Release: 2019-10-24
ISBN 10: 0128197889
ISBN 13: 9780128197882
Language: EN, FR, DE, ES & NL

Proteomic and Metabolomic Approaches to Biomarker Discovery Book Review:

Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research. Addresses the full range of proteomic and metabolomic methods and technologies used for biomarker discovery and validation Covers all steps involved in biomarker discovery, from study design to study execution Serves as a vital resource for biochemists, biologists, analytical chemists, bioanalytical chemists, clinical and medical technicians, researchers in pharmaceuticals and graduate students

The Claustrum: charting a way forward for the brain’s most mysterious nucleus

The Claustrum: charting a way forward for the brain’s most mysterious nucleus
Author: Ariel Y. Deutch, Brian N. Mathur
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2015-09-09
ISBN 10: 2889195422
ISBN 13: 9782889195428
Language: EN, FR, DE, ES & NL

The Claustrum: charting a way forward for the brain’s most mysterious nucleus Book Review:

The claustrum is a long, band-like grey matter structure situated in the ventrolateral telencephalon of most, if not all, mammalian brains. Due to its shape and close proximity to white matter structures and insular cortex, the anatomy and behavioral relevance of the claustrum have proven difficult to study. As a result, disagreements in the literature exist over ontogeny, phylogeny, anatomical boundaries, and connectivity. Despite this, it is generally regarded that the claustrum contains excitatory projection neurons that reciprocally connect to most regions of the cerebral cortex, a feature that has fostered varying hypotheses as to its function. These hypotheses propose multisensory integration, coordination of cortical activity for the generation of conscious percepts, or saliency filtration. The articles of this e-book consider the historical and recent highlights in claustrum structure, hodology, and function and seek to provide a compelling way forward for this “hidden” nucleus.

Molecular Technologies for Detection of Chemical and Biological Agents

Molecular Technologies for Detection of Chemical and Biological Agents
Author: Joseph H. Banoub,Richard M. Caprioli
Publsiher: Springer
Total Pages: 306
Release: 2017-07-05
ISBN 10: 9402411135
ISBN 13: 9789402411133
Language: EN, FR, DE, ES & NL

Molecular Technologies for Detection of Chemical and Biological Agents Book Review:

This book describes the latest molecular insights needed to understand the chemical and biological (CB) agents and their associated biotechnologies. Its primary focus is to present and discuss molecular technologies such as mass spectrometry, chemical and biological sensors, chromatographic and electrophoretic separation, and comparisons of spectroscopic, immunological and molecular analyses of chemicals used for the detection of chemical and biological agents and to prevent terrorism. This NATO-ASI book also contributes to the critical assessment of existing knowledge on new and important detection technologies. It helps to identify directions for future research and to promote closer working relationships between scientists from different professional fields.

Visualizing Chemistry

Visualizing Chemistry
Author: National Research Council,Division on Earth and Life Studies,Board on Chemical Sciences and Technology,Committee on Revealing Chemistry through Advanced Chemical Imaging
Publsiher: National Academies Press
Total Pages: 222
Release: 2006-06-01
ISBN 10: 9780309164634
ISBN 13: 030916463X
Language: EN, FR, DE, ES & NL

Visualizing Chemistry Book Review:

Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imaging—the ability to visualize molecular structures and chemical composition in time and space as actual events unfold—from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.

Spectroscopic Analyses

Spectroscopic Analyses
Author: Eram Sharmin,Fahmina Zafar
Publsiher: BoD – Books on Demand
Total Pages: 240
Release: 2017-12-06
ISBN 10: 9535136275
ISBN 13: 9789535136279
Language: EN, FR, DE, ES & NL

Spectroscopic Analyses Book Review:

The book presents developments and applications of these methods, such as NMR, mass, and others, including their applications in pharmaceutical and biomedical analyses. The book is divided into two sections. The first section covers spectroscopic methods, their applications, and their significance as characterization tools; the second section is dedicated to the applications of spectrophotometric methods in pharmaceutical and biomedical analyses. This book would be useful for students, scholars, and scientists engaged in synthesis, analyses, and applications of materials/polymers.