Nuclear Mechanics and Genome Regulation

Nuclear Mechanics and Genome Regulation
Author: Anonim
Publsiher: Academic Press
Total Pages: 392
Release: 2010-10-12
ISBN 10: 9780123810106
ISBN 13: 0123810108
Language: EN, FR, DE, ES & NL

Nuclear Mechanics and Genome Regulation Book Review:

In recent years new discoveries have made this an exciting and important field of research. This exhaustive volume presents comprehensive chapters and detailed background information for researchers working with in the field of nuclear mechanics and genome regulation. Both classic and state-of-the-art methods readily adaptable and designed to last the test of time Relevant to clinicians and scientists working in a wide range of fields

Introduction to Nuclear Mechanics and Genome Regulation

Introduction to Nuclear Mechanics and Genome Regulation
Author: G.V. Shivashankar
Publsiher: Academic Press
Total Pages: 200
Release: 2019-06-15
ISBN 10: 9780128123454
ISBN 13: 0128123451
Language: EN, FR, DE, ES & NL

Introduction to Nuclear Mechanics and Genome Regulation Book Review:

Introduction to Nuclear Mechanics and Genome Regulation provides a detailed discussion of the biophysical principles underlying nuclear organization and their role in determining tissue function, cell differentiation and homeostasis, and disease expression and management. Applied case studies and full cover images support concept illustration across a diverse range of chapters covering physico-chemical constraints in DNA, 3D organization of chromosomes and functional gene clusters, spatial dimensions of DNA transcription, replication, damage and repair, and more. With its practical approach and foundational focus, this book will be an invaluable reference for students, researchers and clinicians looking to understand this area of cutting-edge study. Contains applied case studies and full color images that support concept illustration Features a diverse range of chapters that cover the fundamentals of nuclear mechanics and genome regulation, including physico-chemical constraints in DNA Introduces advanced biophysical methods, bio-imaging methods, and new molecular biology tools for studying nuclear structures

Lipid Droplets

Lipid Droplets
Author: H. Robert Yang,Peng Li
Publsiher: Academic Press
Total Pages: 270
Release: 2013-10-04
ISBN 10: 0124095216
ISBN 13: 9780124095212
Language: EN, FR, DE, ES & NL

Lipid Droplets Book Review:

This new volume of Methods in Cell Biology looks at lipid droplets LDs, covering sections on analyses of LDs in model systems, cell/tissue-specific analyses of LDs and imaging and in vitro analyses of LD biogenesis and growth. Chapters are written by experts in the field. With cutting-edge material, this comprehensive collection is intended to guide researchers of LDs for years to come. Covers sections on analyses of lipid droplets (LDs) in model systems, cell/tissue-specific analyses of LDs and imaging, and in vitro analyses of LD biogenesis and growth Chapters are written by experts in the field Cutting-edge material

The Zebrafish Cellular and Developmental Biology

The Zebrafish  Cellular and Developmental Biology
Author: Anonim
Publsiher: Academic Press
Total Pages: 366
Release: 2010-12-24
ISBN 10: 9780123848932
ISBN 13: 0123848938
Language: EN, FR, DE, ES & NL

The Zebrafish Cellular and Developmental Biology Book Review:

This volume of Methods in Cell Biology, the first of 3 parts on the subject of zebrafish, provides a comprehensive compendia of laboratory protocols and reviews covering all the new methods developed since 2004. This first volume provides state-of-the-art descriptions of novel cellular imaging technologies and methods for culture of zebrafish stem cells, summarizes protocols for analyzingthe development of major organ systems including the central nervous system (CNS), and introduces the use of the zebrafish as a model system for human diseases. Details state-of-the art zebrafish protocols, delineating critical steps in the procedures as well as potential pitfalls Summarizes the Zebrafish Genome Project

Receptor Receptor Interactions

Receptor Receptor Interactions
Author: P. Michael Conn
Publsiher: Academic Press
Total Pages: 538
Release: 2013-10-18
ISBN 10: 0124104703
ISBN 13: 9780124104709
Language: EN, FR, DE, ES & NL

Receptor Receptor Interactions Book Review:

This new volume of Methods in Cell Biology looks at receptor-receptor interactions, with sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes. With cutting-edge material, this comprehensive collection is intended to guide researchers of receptor-receptor interactions for years to come. Covers sections on allosteric and effector interactions, crystallization and modeling, measuring receptor-receptor interactions and oligomerization in individual classes Chapters are written by experts in the field Cutting-edge material

Molecular and Cellular Mechanobiology

Molecular and Cellular Mechanobiology
Author: Shu Chien,Adam J. Engler,Peter Yingxiao Wang
Publsiher: Springer
Total Pages: 302
Release: 2016-08-10
ISBN 10: 1493956175
ISBN 13: 9781493956173
Language: EN, FR, DE, ES & NL

Molecular and Cellular Mechanobiology Book Review:

This book will cover the cutting-edge developments in molecular and cellular mechanobiology to date. Readers will have a clear understanding of mechanobiology at the molecular and cellular levels, encompassing the mechanosensors, transducers, and transcription. An integrative approach across different scales from molecular sensing to mechanotransduction and gene modulation for physiological regulation of cellular functions will be explored, as well as applications to pathophysiological states in disease. A comprehensive understanding of the roles of physicochemical microenvironment and intracellular responses in determining cellular function in health and disease will also be discussed.

Cell Mechanics

Cell Mechanics
Author: Yu-Li Wang,Dennis E. Discher
Publsiher: Academic Press
Total Pages: 632
Release: 2007-07-05
ISBN 10: 9780080548708
ISBN 13: 0080548709
Language: EN, FR, DE, ES & NL

Cell Mechanics Book Review:

Cell mechanics is the field of study that looks at how cells detect, modify, and respond to the physical properties of the cell environment. Cells communicate with each other through chemical and physical signals which are involved in a range of process from embryogenesis and wound healing to pathological conditions such as cancerous invasion. Similar principles are also likely to be critical for success in regenerative medicine. Cell mechanics is thus central to understanding these principles. As cell mechanics draws from the fields of biology, chemistry, physics, engineering, and mathematics, this book aims not only to provide a collection of research methods, but also to develop a common language among scientists who share the interest in cell mechanics but enter the field with diverse backgrounds. To this end all of the contributing authors have sought to explain in plain language the nature of the biological problems, the rationale for the approaches, in addition to the methods themselves. In addition, to balance practical utility against conceptual advances, Cell Mechanics has intentionally included both chapters that provide detailed recipes and those that emphasize basic principles. Presents a distinctive emphasis on matrix mechanics and their interplay with cell functions Includes highly significant topics relevant to basic and translational research, as well as tissue engineering Emphasizes mechanical input and output of cells

The Nuclear Envelope

The Nuclear Envelope
Author: Sue Shackleton,Philippe Collas,Eric C. Schirmer
Publsiher: Humana Press
Total Pages: 523
Release: 2016-05-05
ISBN 10: 9781493935284
ISBN 13: 1493935283
Language: EN, FR, DE, ES & NL

The Nuclear Envelope Book Review:

This volume provides a wide range of protocols used in studying the nuclear envelope, with special attention to the experimental adjustments that may be required to successfully investigate this complex organelle in cells from various organisms. The Nuclear Envelope: Methods and Protocols is divided into five sections: Part I – Nuclear Envelope Isolation; Part II – Nuclear Envelope Protein Interactions, Localization, and Dynamics; Part III – Nuclear Envelope Interactions with the Cytoskeleton; Part IV – Nuclear Envelope-Chromatin Interactions; and Part V – Nucleo-Cytoplasmic Transport. Many of the modifications discussed in this book have only been circulated within laboratories that have conducted research in this field for many years. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting edge and thorough, The Nuclear Envelope: Methods and Protocols is a timely resource for researchers who have joined this dynamic and rapidly growing field.

International Review of Cell and Molecular Biology

International Review of Cell and Molecular Biology
Author: Anonim
Publsiher: Academic Press
Total Pages: 418
Release: 2016-01-30
ISBN 10: 0128052252
ISBN 13: 9780128052259
Language: EN, FR, DE, ES & NL

International Review of Cell and Molecular Biology Book Review:

International Review of Cell and Molecular Biology presents comprehensive reviews and current advances in cell and molecular biology, and includes articles that address the structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. The series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics authored by prominent cell and molecular biologists. Provides comprehensive reviews and current advances Presents a wide range of perspectives on specific subjects Valuable reference material for advanced undergraduates, graduate students, and professional scientists

Cancer Biology and the Nuclear Envelope

Cancer Biology and the Nuclear Envelope
Author: Eric C. Schirmer,Jose I. de las Heras
Publsiher: Springer Science & Business Media
Total Pages: 611
Release: 2014-02-22
ISBN 10: 1489980326
ISBN 13: 9781489980328
Language: EN, FR, DE, ES & NL

Cancer Biology and the Nuclear Envelope Book Review:

"Nuclear envelope (NE) defects have been linked to cancer biology since the mid-1800s, but it was not until the last few years that we have begun to understand these historical links and to realize that there are myriad ways that the NE impacts on tumorigenesis. The NE is a complex double membrane system that encloses the genome while providing structural support through the intermediate filament lamin polymer and regulating protein/ mRNA trafficking and signaling between the nucleus and cytoplasm via the nuclear pore complexes (NPCs). These functions already provide some mechanisms for NE influences on cancer biology but work in the past few years has elucidated many others. Lamins and many recently identified NE transmembrane proteins (NETs) have been now shown to function in DNA repair, regulation of cell cycle and signaling, apoptosis, cell migration in metastasis and nuclear architecture and morphology. This volume presents a comprehensive overview of the wide range of functions recently identified for NE proteins and their relevance in cancer biology, providing molecular mechanisms and evidence of their value as prognostic and diagnostic markers and suggesting new avenues for the treatment of cancer. Indeed some of these recent links are already yielding promising therapies, such as the current clinical trial of selective inhibitors of the nuclear export factor exportin in certain types of leukemia, melanoma and kidney cancer."

Biomechanics in Oncology

Biomechanics in Oncology
Author: Cheng Dong,Nastaran Zahir,Konstantinos Konstantopoulos
Publsiher: Springer
Total Pages: 376
Release: 2018-10-27
ISBN 10: 3319952943
ISBN 13: 9783319952949
Language: EN, FR, DE, ES & NL

Biomechanics in Oncology Book Review:

This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell mechanics, and platelet-based drug delivery for cancer applications. This is an ideal book for graduate students, biomedical engineers, and researchers in the field of mechanobiology and oncology. This book also: Describes how mechanical properties of cancer cells, the extracellular matrix, tumor microenvironment and immuno-editing, and fluid flow dynamics contribute to tumor progression and the metastatic process Provides the latest research on non-invasive imaging, including traction force microscopy and brillouin confocal microscopy Includes insight into NCIs’ role in supporting biomechanics in oncology research Details how biomaterials in mechano-oncology can be used as a means to tune materials to study cancer

Robbins Basic Pathology E Book

Robbins Basic Pathology E Book
Author: Vinay Kumar,Abul K. Abbas,Jon C. Aster
Publsiher: Elsevier Health Sciences
Total Pages: 928
Release: 2017-03-08
ISBN 10: 0323394132
ISBN 13: 9780323394130
Language: EN, FR, DE, ES & NL

Robbins Basic Pathology E Book Book Review:

Part of the trusted Robbins and Cotran family, Robbins Basic Pathology provides a readable, well-illustrated and concise overview of the principles of human pathology that's ideal for today's busy students. This thoroughly revised edition continues with a strong emphasis on pathogenesis and the clinical features of disease, adding new artwork and more schematic diagrams to further aid in summarizing key pathologic processes and expand the already impressive illustration program. Excellent art program boasts high-quality photomicrographs, gross photos, and radiologic images to supplement the world-class illustrations. Bulleted summary boxes provide quick access to key information and easy review of key concepts. Highlights pathogenesis, morphology, and pathophysiologic content throughout. Includes increased and updated clinical topics. New artwork and more schematic diagrams summarize key pathologic processes.

Quantitative Human Physiology

Quantitative Human Physiology
Author: Joseph J Feher
Publsiher: Academic Press
Total Pages: 1008
Release: 2017-01-02
ISBN 10: 0128011548
ISBN 13: 9780128011546
Language: EN, FR, DE, ES & NL

Quantitative Human Physiology Book Review:

Quantitative Human Physiology: An Introduction is the first text to meet the needs of the undergraduate bioengineering student who is being exposed to physiology for the first time, but requires a more analytical/quantitative approach. This book explores how component behavior produces system behavior in physiological systems. Through text explanation, figures, and equations, it provides the engineering student with a basic understanding of physiological principles with an emphasis on quantitative aspects. Features a quantitative approach that includes physical and chemical principles Provides a more integrated approach from first principles, integrating anatomy, molecular biology, biochemistry and physiology Includes clinical applications relevant to the biomedical engineering student (TENS, cochlear implants, blood substitutes, etc.) Integrates labs and problem sets to provide opportunities for practice and assessment throughout the course NEW FOR THE SECOND EDITION Expansion of many sections to include relevant information Addition of many new figures and re-drawing of other figures to update our understanding and clarify difficult areas Substantial updating of the text to reflect newer research results Addition of several new appendices including statistics, nomenclature of transport carriers, and structural biology of important items such as the neuromuscular junction and calcium release unit Addition of new problems within the problem sets Addition of commentary to power point presentations

An Introduction to Biomaterials

An Introduction to Biomaterials
Author: Jeffrey O. Hollinger
Publsiher: CRC Press
Total Pages: 576
Release: 2005-12-21
ISBN 10: 9780849322822
ISBN 13: 0849322820
Language: EN, FR, DE, ES & NL

An Introduction to Biomaterials Book Review:

The complexity of biological systems and the need to design and develop biomedical therapies poses major challenges to professionals in the biomedical disciplines. An Introduction to Biomaterials emphasizes applications of biomaterials for patient care. Containing chapters prepared by leading authorities on key biomaterial types, this book underscores the process of biomaterial design, development directed toward clinical application, and testing that leads to therapies for clinical targets. The authors provide a lucid perspective on the standards available and the logic behind the standards in which biomaterials address clinical needs. This volume includes chapters on consensus standards and regulatory approaches to testing paradigms, followed by an analysis of specific classes of biomaterials. The book closes with sections on clinical topics that integrate materials sciences and patient applications.

Nuclear Architecture and Dynamics

Nuclear Architecture and Dynamics
Author: Christophe Lavelle,Jean-Marc Victor
Publsiher: Academic Press
Total Pages: 618
Release: 2017-10-27
ISBN 10: 012803503X
ISBN 13: 9780128035030
Language: EN, FR, DE, ES & NL

Nuclear Architecture and Dynamics Book Review:

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field. The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines. Highlights the link between the (bio)chemistry and the (bio)physics of chromatin Deciphers the complex interplay between numerous biochemical factors at task in the nucleus and the physical state of chromatin Provides a collective view of the field by a large, diverse group of authors with both physics and biology backgrounds

Intermediate Filament Associated Proteins

Intermediate Filament Associated Proteins
Author: Anonim
Publsiher: Academic Press
Total Pages: 602
Release: 2016-01-14
ISBN 10: 0128034904
ISBN 13: 9780128034903
Language: EN, FR, DE, ES & NL

Intermediate Filament Associated Proteins Book Review:

Intermediate Filament Associated Proteins, the latest volume in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in intermediate filament associated proteins and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Covers research methods in intermediate filament associated proteins and contains sections on such topics as lamin-associated proteins, intermediate filament-associated proteins and plakin, and other cytoskeletal cross-linkers

An Introduction to Biomaterials Second Edition

An Introduction to Biomaterials  Second Edition
Author: Jeffrey O. Hollinger
Publsiher: CRC Press
Total Pages: 644
Release: 2011-11-28
ISBN 10: 143981256X
ISBN 13: 9781439812563
Language: EN, FR, DE, ES & NL

An Introduction to Biomaterials Second Edition Book Review:

A practical road map to the key families of biomaterials and their potential applications in clinical therapeutics, Introduction to Biomaterials, Second Edition follows the entire path of development from theory to lab to practical application. It highlights new biocompatibility issues, metrics, and statistics as well as new legislation for intellectual property. Divided into four sections (Biology, Biomechanics, Biomaterials Interactions; Biomaterials Testing, Statistics, Regulatory Considerations, Intellectual Property; Biomaterials Compositions; and Biomaterials Applications), this dramatically revised edition includes both new and revised chapters on cells, tissues, and signaling molecules in wound healing cascades, as well as two revised chapters on standardized materials testing with in vitro and in vivo paradigms consistent with regulatory guidelines. Emphasizing biocompatibility at the biomaterial-host interface, it investigates cell-cell interactions, cell-signaling and the inflammatory and complement cascades, specific interactions of protein-adsorbed materials, and other inherent biological constraints including solid-liquid interfaces, diffusion, and protein types. Unique in its inclusion of the practicalities of biomaterials as an industry, the book also covers the basic principles of statistics, new U.S. FDA information on the biomaterials-biology issues relevant to patent applications, and considerations of intellectual property and patent disclosure. With nine completely new chapters and 24 chapters extensively updated and revised with new accomplishments and contemporary data, this comprehensive introduction discusses 13 important classes of biomaterials, their fundamental and applied research, practical applications, performance properties, synthesis and testing, potential future applications, and commonly matched clinical applications. The authors include extensive references, to create a comprehensive, yet manageable didactic work that is an invaluable desk references and instructional text for undergraduates and working professionals alike.

An Introduction to Molecular Evolution and Phylogenetics

An Introduction to Molecular Evolution and Phylogenetics
Author: Lindell Bromham
Publsiher: Oxford University Press
Total Pages: 536
Release: 2016
ISBN 10: 0198736363
ISBN 13: 9780198736363
Language: EN, FR, DE, ES & NL

An Introduction to Molecular Evolution and Phylogenetics Book Review:

DNA can be extracted and sequenced from a diverse range of biological samples, providing a vast amount of information about evolution and ecology. The analysis of DNA sequences contributes to evolutionary biology at all levels, from dating the origin of the biological kingdoms to untanglingfamily relationships.An Introduction to Molecular Evolution and Phylogenetics presents the fundamental concepts and intellectual tools you need to understand how the genome records information about evolutionary past and processes, how that information can be "read", and what kinds of questions we can use thatinformation to answer. Starting with evolutionary principles, and illustrated throughout with biological examples, it is the perfect starting point on the journey to an understanding of the way molecular data is used in modern biology.Online Resource CentreThe Online Resource Centre features:For registered adopters of the book:- Class plans for one-hour hands-on sessions associated with each chapter- Figures from the textbook to view and download

Physics of Cancer

Physics of Cancer
Author: Claudia Mierke
Publsiher: Iop Publishing Limited
Total Pages: 400
Release: 2015-09-22
ISBN 10: 9780750311359
ISBN 13: 0750311355
Language: EN, FR, DE, ES & NL

Physics of Cancer Book Review:

'Physics of Cancer' emphasizes a novel biophysical-based view on cancer disease and metastasis highlighting the functional role of mechanical properties of cells while describing the biological state of cancer. Originating in part from the author's own courses on tumor biology and cellular biophysics, this book is suitable for students and researchers in this dynamic interdisciplinary field, be they from a physical, biological or medical sciences background.

Introduction to Genomics

Introduction to Genomics
Author: Arthur M. Lesk
Publsiher: Oxford University Press
Total Pages: 509
Release: 2017
ISBN 10: 0198754833
ISBN 13: 9780198754831
Language: EN, FR, DE, ES & NL

Introduction to Genomics Book Review:

Our genome is the blueprint for our existence: it encodes all the information we need to develop from a single cell into a hugely complicated functional organism. Yet it is more than a static information store: our genome is a dynamic, tightly-regulated collection of genes, which switch on and off in many combinations to give the variety of cells from which our bodies are formed. But how do we identify the genes that make up our genome? How do we determine their function? And how do different genes form the regulatory networks that direct the processes of life? Introduction to Genomics is the most up-to-date and complete textbook for students approaching the subject for the first time. Lesk's engaging writing style brings a narrative to a disparate field of study and offers a fascinating insight into what can be revealed from the study of genomes. The book covers: the similarities and differences between organisms; how different organisms evolved; how the genome is constructed and how it operates; and what our understanding of genomics means in terms of our future health and wellbeing. The Online Resource Center accompanying Introduction to Genomics features: For students *Extensive and imaginative weblems (web-based problems) for each chapter designed to give you practice with the tools required for further study and research in the field *Hints and answers to end-of-chapter problems and exercises support your self-directed learning *Guided tour of websites and major archival databanks in genomics offer a wealth of resources to springboard your own research *Journal club: links to related research articles on topics covered in the book are paired with engaging questions to improve your interpretation of the primary literature *Rotating figures allow you to visualize complex structures For instructors *Downloadable figures from the book.