Translational Immunotherapy of Brain Tumors

Translational Immunotherapy of Brain Tumors
Author: John H. Sampson
Publsiher: Academic Press
Total Pages: 404
Release: 2017-02-06
ISBN 10: 0128026251
ISBN 13: 9780128026250
Language: EN, FR, DE, ES & NL

Translational Immunotherapy of Brain Tumors Book Review:

Translational Immunotherapy of Brain Tumors gives researchers and practitioners an up-to-date and comprehensive overview of the field. Chapters include adoptive immunotherapy, immunosuppression, CAR therapy of brain tumors, and dendritic cell therapy for brain tumors. Very few agents have been shown to be efficacious in the treatment of malignant gliomas. Recently, there have been a number of studies demonstrating the potential success of immunotherapy for brain tumors. Immunotherapeutics are becoming the most frequent drugs to be used in cancer therapy. These new breakthroughs, now approved by the FDA, are a part of multiple phase III international trials and ongoing research in malignant glioma, meaning that the information in this cutting-edge book will be of great importance to practitioners and researchers alike. Comprehensive overview, providing an update on immunology, translational immunotherapy, and clinical trials relating to malignant gliomas Edited by a prominent neurosurgeon with contributions by leading researchers in the field Ideal resource for researchers and practitioners interested in learning about mechanisms that use the immune system to treat brain tumors

Handbook of Brain Tumor Chemotherapy Molecular Therapeutics and Immunotherapy

Handbook of Brain Tumor Chemotherapy  Molecular Therapeutics  and Immunotherapy
Author: Herbert B. Newton
Publsiher: Academic Press
Total Pages: 848
Release: 2018-03-28
ISBN 10: 0128121017
ISBN 13: 9780128121016
Language: EN, FR, DE, ES & NL

Handbook of Brain Tumor Chemotherapy Molecular Therapeutics and Immunotherapy Book Review:

Handbook of Brain Tumor Chemotherapy, Molecular Therapeutics, and Immunotherapy, Second Edition, provides a comprehensive overview of the molecular methodologies in the neuro-oncology field. There have been profound changes in the landscape of approaches to brain tumor therapy since the first edition—mainly in the areas of molecular biology and molecular therapeutics, as well as in the maturation of immunotherapy approaches (e.g., vaccines). This updated edition has a new, primary focus on multidisciplinary molecular methods, and is broadened to include the latest cutting-edge molecular biology, therapeutics, immunobiology and immunotherapy approaches. As the first comprehensive book to address the molecular research into these concepts, users will find it to be an invaluable resource on the topics discussed. Provides the most up-to-date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics for the treatment of brain tumors Broadly appeals to anyone interested in neuro-oncology and the treatment of brain tumors Features updated chapters on molecular biology, molecular therapeutics, maturation of immunotherapy approaches, and a focus on multidisciplinary molecular methods Includes a new section on the basic science of immunology, as well as thorough updates on the use of vaccine technology and immunotherapy for the treatment of brain tumors

Intracranial Gliomas Part III Innovative Treatment Modalities

Intracranial Gliomas Part III   Innovative Treatment Modalities
Author: M.F. Chernov,Y. Muragaki,S. Kesari,I.E. McCutcheon
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 222
Release: 2018-07-10
ISBN 10: 3318060631
ISBN 13: 9783318060638
Language: EN, FR, DE, ES & NL

Intracranial Gliomas Part III Innovative Treatment Modalities Book Review:

At present most intracranial gliomas are considered incurable with current treatment strategies, and the search for new modalities that may effectively control tumor growth continues. The chapters in this volume describe basic principles and therapeutic possibilities of several innovative techniques, including photodynamic therapy, laser-induced interstitial thermotherapy, stereotactic cryodestruction, high-intensity focused ultrasound ablation, boron neutron capture therapy, proton and carbon ion irradiation, targeted therapy, immunotherapy, gene therapy, local chemotherapy, and alternating electric fields therapy. Potential applications of extracellular vesicles and nanotechnology for management of gliomas are highlighted as well. Many of these methods have already demonstrated antitumor efficacy in clinical testing, whereas others are still under development. The materials presented in this book are mainly directed at clinicians treating patients with brain tumors, as well as clinical and basic researchers working in the field of neuro-oncology.

Glioma

Glioma
Author: ryuya yamanaka
Publsiher: Springer Science & Business Media
Total Pages: 232
Release: 2012-05-27
ISBN 10: 1461431468
ISBN 13: 9781461431466
Language: EN, FR, DE, ES & NL

Glioma Book Review:

Treatment of glioma is currently one of the most challenging problems in oncology, as well as in neurosurgery. Despite major advances in our understanding of the pathomechanism, diagnosis by imaging and the availability of powerful therapeutic tools, the life expectancy of patients with glioblastoma has only been slightly prolonged and a cure remains elusive. None of the currently available surgical tools, including operative microscopes, lasers and image-guided surgery, can enable the detection and removal of all of the tumor tissue. In recent years, however, the landscape has been changing immeasurably, and molecular studies over the past two decades have identified a variety of genetic aberrations that are specifically associated with individual types of gliomas. In addition, certain molecular abnormalities have been linked to therapy responses, thereby establishing clinical biomarkers and molecular targets, and the use of novel agents is being investigated. These agents have been specifically engineered to exert specific cytotoxicity against gliomas, either on their own as single agents or in combination with other modalities. Moreover, there has been an enormous surge of interest in the area of immunology and immunotherapy, which has been facilitated by our understanding of the molecular basis of gliomas. Although several kinds of immunotherapeutic trials have been undertaken, we still await a great breakthrough in terms of clinical efficacy to prolong the survival time of glioma patients.

Brain Tumor Immunotherapy

Brain Tumor Immunotherapy
Author: Linda M. Liau,Donald P. Becker,Timothy F. Cloughesy,Darell D. Bigner
Publsiher: Springer Science & Business Media
Total Pages: 374
Release: 2000-11-10
ISBN 10: 1592590357
ISBN 13: 9781592590353
Language: EN, FR, DE, ES & NL

Brain Tumor Immunotherapy Book Review:

An authoritative panel of researchers and clinicians critically reviews the entire field to provide a comprehensive guide to modern brain tumor immunotherapy and thereby enhance future research in this area. The contributors detail many of the key laboratory experiments and clinical protocols that are currently being investigated, integrate the available information from previous and ongoing research, and help define the current status of the field. Topics range from adoptive cellular and antibody-mediated immunotherapy of brain tumors to tumor vaccines and related strategies, and include many vanguard experimental strategies and immunological techniques for studying brain tumor immunotherapy. Cutting-edge and comprehensive, Brain Tumor Immunotherapy brings together all the important recent advances in our understanding of central nervous system tumor immunology and illustrates in powerful detail the many new applications now harnessing the immune response for brain tumor therapeutics.

New Techniques for Management of Inoperable Gliomas

New Techniques for Management of    Inoperable    Gliomas
Author: Michael E. Sughrue,Isaac Yang
Publsiher: Academic Press
Total Pages: 256
Release: 2019-08-03
ISBN 10: 0128136340
ISBN 13: 9780128136348
Language: EN, FR, DE, ES & NL

New Techniques for Management of Inoperable Gliomas Book Review:

New Techniques for Management of 'Inoperable' Gliomas radically challenges the assumption that certain gliomas cannot be removed with modern techniques, contesting stereotypical thinking and establishing new paradigms in the field. Gliomas are primary brain tumors which are often fatal. Recent data has demonstrated that despite the fact that surgery cannot cure gliomas, patient survival is substantially improved by removing as much of the tumor as possible. This fact has raised the imperative that neurologists try to improve techniques to bring surgical resection to as many patients as possible. This book brings new insights and technologies to the forefront, giving hope to patients. Provides the first comprehensive book to discuss techniques for removing gliomas that are traditionally deemed ‘inoperable’ Presents a great reference tool that challenges stereotypical thinking by offering techniques by innovative surgeons Includes chapters that are organized by different glioma types and surgery/techniques

The Duke Glioma Handbook

The Duke Glioma Handbook
Author: Allan H. Friedman
Publsiher: Cambridge University Press
Total Pages: 220
Release: 2016-03-31
ISBN 10: 1107065976
ISBN 13: 9781107065970
Language: EN, FR, DE, ES & NL

The Duke Glioma Handbook Book Review:

Provides a summary of glioma biology, genetics and management, based on the world-leading Duke University Preston Robert Tisch Brain Tumor Center program.

Glioblastoma

Glioblastoma
Author: Swapan K. Ray
Publsiher: Springer Science & Business Media
Total Pages: 431
Release: 2009-10-31
ISBN 10: 9781441904102
ISBN 13: 1441904107
Language: EN, FR, DE, ES & NL

Glioblastoma Book Review:

Glioblastoma is the most malignant brain tumor that still remains incurable. It is such a deadly disease that patients do not survive more than a few months after diagnosis. Our understanding of the histopathology and molecular mechanisms of formation of glioblastoma is rapidly advancing so as to provide us clues for devising rational therapeutic strategies for treatment of this malignancy. It is important that we continue to improve our knowledge about the pathogenesis of this devastating disease and explore new areas to find successful therapeutic strategies. Various approaches such as sophisticated imaging techniques, improved surgical procedures, ground-breaking strategies for radiotherapy, chemotherapy, immunotherapy, chemoimmunotherapy, and photodynamic therapy are being used for eradicating glioblastoma. Hopefully, this book will be an important source of information on glioblastoma and therefore be highly useful to the students, postdoctoral fellows, principal investigators, and clinicians involved in this field.

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1994
ISBN 10:
ISBN 13: UIUC:30112023523415
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Review:

Neurooncology

Neurooncology
Author: Amit Agrawal
Publsiher: BoD – Books on Demand
Total Pages: 488
Release: 2016-07-13
ISBN 10: 9535124250
ISBN 13: 9789535124252
Language: EN, FR, DE, ES & NL

Neurooncology Book Review:

The book contains the information of various aspects of newer developments and recent advances in the field of central nervous system (CNS) tumor molecular biology, tumor progression, clinical presentation, imaging and management. The authors from different reputed institutions shared their knowledge on this open access platform to disseminate their knowledge at global level. As it is obvious in the current text, the field of neurooncology is heterogeneous and under continuous development with addition of new knowledge and information on regular basis. The collective contributions from experts attempt to provide updates regarding ongoing research and developments pertaining to CNS tumor genetics and molecular aspects and their applied aspect in reference to patient management.

Central Nervous System Cancers

Central Nervous System Cancers
Author: Oncology Nursing Society
Publsiher: Unknown
Total Pages: 151
Release: 2011
ISBN 10: 9781890504984
ISBN 13: 189050498X
Language: EN, FR, DE, ES & NL

Central Nervous System Cancers Book Review:

Considered one of the most devastating and frightening of all cancers, cancers of the central nervous system (CNS) attack the complex organs that control not only the CNS but also the peripheral nervous system and many of the voluntary and involuntary body systems, with 20% to 40% of CNS cancers metastasizing to the brain. Site-Specific Cancer Series: Central Nervous System Cancers, a new volume in the Series edited by Deborah Hutchinson Allen and Laurie L. Rice, details the cancers of the brain and spinal cord. Chapters examine issues such as anatomy and physiology of the brain and spine, patient assessment, pathology, histology, and molecular markers of primary brain tumors, and adult and pediatric cancers of the brain and spinal cord. Other issues include treatment modalities (surgical treatments, chemotherapy, and radiotherapy), as well as pediatric therapeutic modalities, symptom management and psychological issues, and the current state of evidence-based practice. You can use this new volume as a guide to treating your patients and to providing sensitive and realistic care that optimizes the quality of life and permits a sense of hopefulness to prevail when many patients with type of cancer feel only pain and fear.

Brain Tumors

Brain Tumors
Author: Amit Agrawal,Luis Rafael Moscote-Salazar
Publsiher: BoD – Books on Demand
Total Pages: 248
Release: 2018-08-22
ISBN 10: 1789235561
ISBN 13: 9781789235562
Language: EN, FR, DE, ES & NL

Brain Tumors Book Review:

We all know that the field of neuro-oncology is heterogeneous and under continuous development with the addition of new knowledge and information on a regular basis. The present book "Brain Tumor - An Update" is an attempt to share the personal experiences of experts who are involved in neuro-oncology-related research. Through this book, the authors share their experiences and provide details about the pathophysiology, neuroimaging approaches, and management options, and how to go about decision-making in patients with brain tumors. We hope that the valuable contributions from the authors shall facilitate understanding about brain tumors. I am grateful to all the authors who have contributed their tremendous expertise, and I would like to acknowledge the outstanding support of Ms. Danijela Sakic, Author Service Manager, IntechOpen Science, who collaborated tirelessly in crafting this book.

Gliomas

Gliomas
Author: Anonim
Publsiher: Academic Press
Total Pages: 464
Release: 2016-03-02
ISBN 10: 0128030070
ISBN 13: 9780128030073
Language: EN, FR, DE, ES & NL

Gliomas Book Review:

Researchers’ knowledge of gliomas continues to advance rapidly at both the basic and translational levels, and Gliomas provides a thorough overview of the evolving fields of tumor biology and clinical medicine as they relate to our understanding of brain tumors. Gliomas reviews the current paradigms that underlie these fields, beginning with the molecular epidemiology of glioma susceptibility and prognosis through population-based science and genome-wide association studies. The book’s discussion of imaging modalities extends beyond advances in anatomical imaging to include metabolic and physiological studies. This work provides thorough discussion of the clinical view of tumors, ranging from the presentation of the patient to surgical management, and covers all therapeutic options for patient care, including chemotherapy, targeted molecular therapies, immunotherapies, and even personalized approaches to impact the set of lesions. Additionally, the book discusses radiotherapy with regard to the many options available to treat patients using myriad fractionated techniques with various sources. Finally, Gliomas reviews issues specific to the quality of life for patients, and techniques for maximizing the effect of caregivers. Edited and authored by premier researchers from around the world, Gliomas is a comprehensive reference for clinicians and researchers seeking the most up-to-date information on gliomas, and a guide to the best ways to effectively manage glioma patients and their care. Synthesizes widely dispersed information on the management of gliomas into one comprehensive resource Chapters written by international authors who are preeminent researchers in the field Fully explores the therapeutic options for patient care, from chemotherapy to radiotherapy to personalized approaches

Oligodendroglioma

Oligodendroglioma
Author: Nina A. Paleologos,Herbert B. Newton
Publsiher: Academic Press
Total Pages: 422
Release: 2019-06-18
ISBN 10: 0128131594
ISBN 13: 9780128131596
Language: EN, FR, DE, ES & NL

Oligodendroglioma Book Review:

Oligodendroglioma: Clinical Presentation, Pathology, Molecular Biology, Imaging, and Treatment features the latest "cutting-edge" molecular biology, molecular therapeutics, imaging, immunotherapy, and research methods on the topic of oligodendrogliomas. The most detailed and comprehensive resource on the subject, it provides up-to-date information on clinical presentation, pathology, molecular biology, and treatment methods, including immunotherapy. This book is a critical for students, physicians and researchers in the fields of neuroscience, neuro-oncology, neurosurgery, radiation oncology, medical oncology, and others working in research or with patients. Provides the most up-to-date information regarding the clinical presentation, pathology, molecular biology, and methods for the treatment of oligodendroglioma brain tumors, including surgical therapy, radiotherapy, molecular therapeutics, chemotherapy, and immunotherapy Broadly appeals to anyone interested in the field of neuro-oncology and the treatment of patients with oligodendrogliomas Useful to clinicians interested in a thorough overview of the basic science and treatment of oligodendrogliomas Includes a section on immunotherapy, with updates on the use of vaccines and immune-based treatment approaches applied to oligodendrogliomas

Brain Tumors

Brain Tumors
Author: Ana Lucia Abujamra
Publsiher: BoD – Books on Demand
Total Pages: 434
Release: 2011-08-23
ISBN 10: 9533075880
ISBN 13: 9789533075884
Language: EN, FR, DE, ES & NL

Brain Tumors Book Review:

Brain Tumors: Current and Emerging Therapeutic Strategies focuses on tumor models, the molecular mechanisms involved in the pathogenesis of this disease, and on the new diagnostic and treatment strategies utilized to stage and treat this malignancy. A special section on immunotherapy and gene therapy provides the most up-to-date information on the pre-clinical and clinical advances of this therapeutic venue. Each chapter in Brain Tumors: Current and Emerging Therapeutic Strategies is authored by international experts with extensive experience in the areas covered.

New Approaches to the Management of Primary and Secondary CNS Tumors

New Approaches to the Management of Primary and Secondary CNS Tumors
Author: Lee Roy Morgan
Publsiher: BoD – Books on Demand
Total Pages: 214
Release: 2017-03-23
ISBN 10: 953513051X
ISBN 13: 9789535130512
Language: EN, FR, DE, ES & NL

New Approaches to the Management of Primary and Secondary CNS Tumors Book Review:

Several new concepts are reviewed and discussed in this book and allude to the transport of drugs bound to red blood cells into the vascular blood-brain barrier and into cancer cells. Such a transport system is novel and of potential therapeutic potential. It is the goal of this book to provide information and data that will be useful for others to develop new approaches for the management of CNS malignancies.

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor
Author: Terry Lichtor
Publsiher: BoD – Books on Demand
Total Pages: 434
Release: 2015-03-25
ISBN 10: 953512031X
ISBN 13: 9789535120315
Language: EN, FR, DE, ES & NL

Molecular Considerations and Evolving Surgical Management Issues in the Treatment of Patients with a Brain Tumor Book Review:

A dramatic increase in knowledge regarding the molecular biology of brain tumors has been established over the past few years. In particular, recent new avenues regarding the role of microRNAs along with further understanding of the importance of angiogenesis, immunotherapy and explanations for the resistance of the tumors to radiation therapy have been developed. A discussion of certain surgical management issues including improvements in imaging along with issues concerning tumor induced epilepsy is included. It is hopeful that this new information will lead to efficacious treatment strategies for these tumors which remain a challenge. In this book, a review of the latest information on these topics along with a variety of new therapeutic treatment strategies with an emphasis on molecular targeted therapies is provided.

Critical Reviews in Immunology

Critical Reviews in Immunology
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2009
ISBN 10:
ISBN 13: STANFORD:36105123121720
Language: EN, FR, DE, ES & NL

Critical Reviews in Immunology Book Review:

Glioma

Glioma
Author: Ibrahim Omerhodzic,Kenan Arnautovic
Publsiher: BoD – Books on Demand
Total Pages: 258
Release: 2019-01-16
ISBN 10: 1789849535
ISBN 13: 9781789849530
Language: EN, FR, DE, ES & NL

Glioma Book Review:

The past three decades have been marked with huge enthusiasm from scientists and professionals in an effort to find a cure for glioma disease. Methods to confirm the kinds and grades of glioma have taken a path from classical macro- to microscopic pathohystological confirmation of tumors, through morphological-histological, molecular, and genetic diagnosis. Surgically, progress was made possible with the development and use of technological aids, for example neuronavigation, cortical mapping, electrocorticography, neuromonitoring, functional and intraoperative MRI, magnetoencephalography, etc. Great hope was placed on the extension of tumor resection and popular supratotal resection. Significant progress has been made generally in glioma treatment with the use of modern radiotherapy and new chemotherapeutics. What do we want to see for the future? By way of stem cells, a specific medicine will be produced, individualized for the particular patient, and by using a microcapsule it will be implanted into the brain zone affected by the tumor by way of robot surgery and injection needle. This is not at all an unrealistic expectation in the next decade or two.

Modern Management of High Grade Glioma Part II An Issue of Neurosurgery Clinics E Book

Modern Management of High Grade Glioma  Part II  An Issue of Neurosurgery Clinics   E Book
Author: Isaac Yang,Seunggu J. Han
Publsiher: Elsevier Health Sciences
Total Pages: 240
Release: 2012-07-15
ISBN 10: 1455747688
ISBN 13: 9781455747689
Language: EN, FR, DE, ES & NL

Modern Management of High Grade Glioma Part II An Issue of Neurosurgery Clinics E Book Book Review:

Standard therapy for high grade glioma is a topic that is evolving, timely, and relevant. Guest Editors Isaac Yang, MD and Seunggu Han, MD have assembled a group of experts on management of high grade glioma. Some of the articles in this issue include: Use of language mapping to aid resection of eloquent gliomas; Clinical trials with immunotherapy; Clinical trials for small molecule inhibitors; Nanotechnology potential applications for GBM therapy; High Grade Gliomas in children; Modern Advances in Brain Tumor Treatments; Molecular pathways of Avastin interactions for the treatment of glioblastoma; and Quality of Life and Outcomes in Glioblastoma management.