Ending Aging

Ending Aging
Author: Aubrey de Grey,Michael Rae
Publsiher: St. Martin's Press
Total Pages: 400
Release: 2007-09-04
ISBN 10: 9781429931830
ISBN 13: 1429931833
Language: EN, FR, DE, ES & NL

Ending Aging Book Review:

MUST WE AGE? A long life in a healthy, vigorous, youthful body has always been one of humanity's greatest dreams. Recent progress in genetic manipulations and calorie-restricted diets in laboratory animals hold forth the promise that someday science will enable us to exert total control over our own biological aging. Nearly all scientists who study the biology of aging agree that we will someday be able to substantially slow down the aging process, extending our productive, youthful lives. Dr. Aubrey de Grey is perhaps the most bullish of all such researchers. As has been reported in media outlets ranging from 60 Minutes to The New York Times, Dr. de Grey believes that the key biomedical technology required to eliminate aging-derived debilitation and death entirely—technology that would not only slow but periodically reverse age-related physiological decay, leaving us biologically young into an indefinite future—is now within reach. In Ending Aging, Dr. de Grey and his research assistant Michael Rae describe the details of this biotechnology. They explain that the aging of the human body, just like the aging of man-made machines, results from an accumulation of various types of damage. As with man-made machines, this damage can periodically be repaired, leading to indefinite extension of the machine's fully functional lifetime, just as is routinely done with classic cars. We already know what types of damage accumulate in the human body, and we are moving rapidly toward the comprehensive development of technologies to remove that damage. By demystifying aging and its postponement for the nonspecialist reader, de Grey and Rae systematically dismantle the fatalist presumption that aging will forever defeat the efforts of medical science.

Human Aging

Human Aging
Author: Paul W. Foos,M. Cherie Clark
Publsiher: Routledge
Total Pages: 508
Release: 2016-01-08
ISBN 10: 131735107X
ISBN 13: 9781317351078
Language: EN, FR, DE, ES & NL

Human Aging Book Review:

This text offers a readable and friendly presentation of the important methods, findings, and theories of human aging, while actively involving the reader in meaningful exercises and critical thinking. Students are repeatedly challenged to apply information in the text to the older adults in their own lives. Specifically, suggestions for enhancing the lives of their older relatives are offered and encouraged. These include guidelines for discussions they might have regarding social, emotional, and environmental changes as well encouraging intellectual and social interaction. In this Edition: Emphasis on the science of the study of aging and why questions in aging are difficult to answer, how social scientists attempt to handle such difficulties, and the successes and failures social scientists have had thus far in answering those questions. The text also demonstrates how current research findings are now being applied in the real world and/or how they might be applied in the future. Cross-cultural comparisons and ethnic group comparisons are included wherever possible. Each chapter begins with "Senior View," which introduces students to a real person and gives them a chance to hear what older adults think and say about important issues related to the chapter and a chance to compare those opinions to the research findings. Each chapter ends with "Making Choices," emphasizing the important behavioral, emotional, and social choices that students can make now to prolong a healthy, happy life. "Chapter Projects" offer the opportunity for active learning, as students investigate for themselves an issue related to the chapter. Instructors can expand these projects for students who want to learn more, or for independent study. "Focus on Aging" boxes compliment the material in the text, providing additional insight and examples, and encouraging critical thinking. Every chapter includes discussion questions, study questions, chapter exercises, and related online resources.

Human Aging

Human Aging
Author: Calogero Caruso,Giuseppina Candore
Publsiher: Academic Press
Total Pages: 382
Release: 2021-05-21
ISBN 10: 0128227370
ISBN 13: 9780128227374
Language: EN, FR, DE, ES & NL

Human Aging Book Review:

Human Aging: From Cellular Mechanisms to Therapeutic Strategies offers an exhaustive picture of all the biological aspects of human aging by describing the key mechanisms associated with human aging and covering events that could disrupt the normal course of aging. Each chapter includes a summary of the salient points covered, along with futures prospects. The book provides readers with the information they need to gain or deepen the skills needed to evaluate the mechanisms of aging and age-related diseases and to monitor the effectiveness of therapies aimed at slowing aging. The book encourages PhD and Postdoc students, researchers, health professionals and others interested in the biology of aging to explore the fascinating and challenging questions about why and how we age as well as what can and cannot be done about it. Concentrates on different processes, e.g., oxidative stress, cellular senescence and Inflammaging Offers the ability to access cross-sectional knowledge more easily Written by expert researchers in biogerontology who are actively involved in various fields within aging research

Handbook of Models for Human Aging

Handbook of Models for Human Aging
Author: P. Michael Conn
Publsiher: Elsevier
Total Pages: 1075
Release: 2011-04-28
ISBN 10: 9780080460062
ISBN 13: 0080460062
Language: EN, FR, DE, ES & NL

Handbook of Models for Human Aging Book Review:

The Handbook of Models for Human Aging is designed as the only comprehensive work available that covers the diversity of aging models currently available. For each animal model, it presents key aspects of biology, nutrition, factors affecting life span, methods of age determination, use in research, and disadvantages/advantes of use. Chapters on comparative models take a broad sweep of age-related diseases, from Alzheimer's to joint disease, cataracts, cancer, and obesity. In addition, there is an historical overview and discussion of model availability, key methods, and ethical issues. Utilizes a multidisciplinary approach Shows tricks and approaches not available in primary publications First volume of its kind to combine both methods of study for human aging and animal models Over 200 illustrations

Biomarkers of Human Aging

Biomarkers of Human Aging
Author: Alexey Moskalev
Publsiher: Springer Nature
Total Pages: 421
Release: 2019-09-13
ISBN 10: 3030249700
ISBN 13: 9783030249700
Language: EN, FR, DE, ES & NL

Biomarkers of Human Aging Book Review:

This book collects and reviews, for the first time, a wide range of advances in the area of human aging biomarkers. This accumulated data allows researchers to assess the rate of aging processes in various organs and systems, and to individually monitor the effectiveness of therapies intended to slow aging. In an introductory chapter, the editor defines biomarkers of aging as molecular, cellular and physiological parameters that demonstrate reproducible changes - quantitative or qualitative - with age. The introduction recounts a study which aimed to create a universal model of biological age, whose most predictive parameters were albumin and alkaline phosphatase (indication liver function), glucose (metabolic syndrome), erythrocytes (respiratory function) and urea (renal function). The book goes on to describe DNA methylation, known as the “epigenetic clock,” as currently the most comprehensive predictor of total mortality. It is also useful for predicting mortality from cancer and cardiovascular diseases, and for analyzing the effects of lifestyle factors including diet, exercise, and education. Individual contributions draw additional insight from research on genetics and epigenetic aging markers, and immunosenescence and inflammaging markers. A concluding chapter outlines the challenge of integrating of biological and clinical markers of aging. Biomarkers of Human Aging is written for professionals and practitioners engaged in the study of aging, and will be useful to both advanced students and researchers.

Experimental Psychology Cognition and Human Aging

Experimental Psychology  Cognition  and Human Aging
Author: Donald H. Kausler
Publsiher: Springer Science & Business Media
Total Pages: 856
Release: 2012-12-06
ISBN 10: 1461396956
ISBN 13: 9781461396956
Language: EN, FR, DE, ES & NL

Experimental Psychology Cognition and Human Aging Book Review:

This book is a major revision and extension of my earlier book, Experimental Psychology and Human Aging, which appeared in 1982. The intervening years have seen a remarkable expansion of psychological research on human aging, especially on topics dealing with cognition. They have also seen research on cognitive aging gain increasing importance within the mainstream of basic cognitive research. As my lecture notes for my course in the psychology of aging grew, so did my apprehension regarding the task ahead of me in revis ing the first edition. The research explosion in cognitive aging forced several major changes in content from the first to the second edition. Two chapters on learning and memory in the first edition were necessarily expanded to six chapters in the present edition. Similarly, the single prior chapter on percep tion and attention became two chapters, as did the single prior chapter on thinking. Another change from the first edition is in the addition of some review of the effects of abnormal aging on various cognitive processes, parti cularly in regard to memory functioning. To keep the revision within reason able length, some sacrifices had to be made. The multiple chapters on metho dology and theory in the first edition were condensed into the present, single chapter. However, the major topics from the first edition were retained and, in fact, added to by the inclusion of important topics and issues that emerged over the past eight years.

Exercise as a Countermeasure to Human Aging

Exercise as a Countermeasure to Human Aging
Author: Bradley Elliott,Lawrence D. Hayes,David C. Hughes,Martin Burtscher
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2020-11-12
ISBN 10: 2889660109
ISBN 13: 9782889660100
Language: EN, FR, DE, ES & NL

Exercise as a Countermeasure to Human Aging Book Review:

Brain Aging

Brain Aging
Author: David R. Riddle
Publsiher: CRC Press
Total Pages: 408
Release: 2007-04-19
ISBN 10: 9781420005523
ISBN 13: 1420005529
Language: EN, FR, DE, ES & NL

Brain Aging Book Review:

Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

The Telomerase Revolution

The Telomerase Revolution
Author: Michael Fossel
Publsiher: BenBella Books, Inc.
Total Pages: 256
Release: 2015-10-06
ISBN 10: 1941631703
ISBN 13: 9781941631706
Language: EN, FR, DE, ES & NL

The Telomerase Revolution Book Review:

One of Wall Street Journal's "Best Books for Science Lovers" in 2015 Science is on the cusp of a revolutionary breakthrough. We now understand more about aging—and how to prevent and reverse it—than ever before. In recent years, our understanding of the nature of aging has grown exponentially, and dramatic life extension—even age reversal—has moved from science fiction to real possibility. Dr. Michael Fossel has been in the forefront of aging research for decades and is the author of the definitive textbook on human aging. In The Telomerase Revolution, he takes us on a detailed but highly accessible scientific journey, providing startling insights into the nature of human aging. Twenty years ago, there was still considerable debate of the nature of human aging, with a variety of competing theories in play. But scientific consensus is forming around the telomere theory of aging. The essence of this theory is that human aging is the result of cellular aging. Every time a cell reproduces, its telomeres (the tips of the chromosomes) shorten. With every shortening of the telomeres, the cell's ability to repair its molecules decreases. It ages. Human aging is the result of the aging of the body's trillions of cells. But some of our cells don't age. Sex cells and stem cells can reproduce indefinitely, without aging, because they create telomerase. Telomerase re-lengthens the telomeres, keeping these cells young. The Telomerase Revolution describes how telomerase will soon be used as a powerful therapeutic tool, with the potential to dramatically extend life spans and even reverse human aging. Telomerase-based treatments are already available, and have shown early promise, but much more potent treatments will become available over the next decade. The Telomerase Revolution is the definitive work on the latest science on human aging, covering both the theory and the clinical implications. It takes the reader to the forefront of the upcoming revolution in human medicine.

Time of Our Lives The Science of Human Aging

Time of Our Lives   The Science of Human Aging
Author: Tom Kirkwood Professor of Biological Gerontology University of Manchester
Publsiher: Oxford University Press, USA
Total Pages: 288
Release: 1999-06-23
ISBN 10: 019802939X
ISBN 13: 9780198029397
Language: EN, FR, DE, ES & NL

Time of Our Lives The Science of Human Aging Book Review:

As recent articles about "the graying of America" suggest, a demographic revolution is well underway. The number of people living into extreme old age is increasing dramatically. By the year 2050 one in five of the world's population, including the developing countries, will be 65 or older, a fact which presages profound medical, biological, philosophical, and political changes in the coming century. In Time of Our Lives, Tom Kirkwood unfolds some of the deepest mysteries of medical science while demolishing some of the most persistent misconceptions. He overturns the almost universally held belief that aging is either necessary or inevitable--it isn't--and debunks the idea that there exists a "death gene" that evolved to inhibit population growth. Instead, Kirkwood shows that we age because our genes, evolving at a time when life was "nasty, brutish, and short," placed little priority on the long-term maintenance of our bodies. With such knowledge, along with new insights from genome research, we can devise ways to target the root causes of aging and of age-related diseases such as Alzheimer's and osteoporosis. Expanding his thesis of the "disposable soma," developed over twenty years of research, Kirkwood makes sense of the evolution of aging, explains how aging occurs, and answers fundamental questions like why women live longer than men. He even considers the possibility that human beings will someday have greatly extended life spans or even be free from senescence altogether. Beautifully written by one of the world's pioneering researchers into the science of aging, Time of Our Lives is a clear, original and, above all, inspiring investigation of a process all of us experience but few of us understand.

Long lived Proteins in Human Aging and Disease

Long lived Proteins in Human Aging and Disease
Author: Roger J. W. Truscott
Publsiher: John Wiley & Sons
Total Pages: 224
Release: 2021-02-16
ISBN 10: 3527347283
ISBN 13: 9783527347285
Language: EN, FR, DE, ES & NL

Long lived Proteins in Human Aging and Disease Book Review:

This authoritative overview on an emerging topic in the molecular life sciences covers all aspects of the aging of (long-lived) proteins. It describes the molecular mechanisms of aging on the protein level, in particular the most common side chain modifications and includes analytical methods to study protein half-life and the accumulation of modifications. Finally, the impact of protein aging on several age-related disases in humans is dissected, and their role in limiting human lifespan is discussed.

Biology of Human Aging

Biology of Human Aging
Author: Alexander P. Spence
Publsiher: Benjamin-Cummings Publishing Company
Total Pages: 236
Release: 1995
ISBN 10: 1928374650XXX
ISBN 13: CORNELL:31924063026417
Language: EN, FR, DE, ES & NL

Biology of Human Aging Book Review:

For one-semester introductory-level courses in the Biology of Human Aging, for non-majors. A general — yet substantive — overview of the aging process, this text explores age-related changes and age-related dysfunctions common to each body system. Scientific terminology is kept to a minimum.

Time of Our Lives

Time of Our Lives
Author: Tom Kirkwood
Publsiher: Oxford University Press
Total Pages: 288
Release: 2001-01-11
ISBN 10: 0195350006
ISBN 13: 9780195350005
Language: EN, FR, DE, ES & NL

Time of Our Lives Book Review:

By the year 2050 one in five of the world's population will be 65 or older, a fact which presages profound medical, biological, philosophical, and political changes in the coming century. In Time of Our Lives, Tom Kirkwood draws on more than twenty years of research to make sense of the evolution of aging, to explain how aging occurs, and to answer fundamental questions like why women live longer than men. He shows that we age because our genes, evolving at a time when life was "nasty, brutish, and short," placed little priority on the long-term maintenance of our bodies. With such knowledge, along with new insights from genome research, we can devise ways to target the root causes of aging and of age-related diseases such as Alzheimer's and osteoporosis. He even considers the possibility that human beings will someday have greatly extended life spans or even be free from senescence altogether. Beautifully written by one of the world's pioneering researchers into the science of aging, Time of Our Lives is a clear, original and, above all, inspiring investigation of a process all of us experience but few of us understand.

Conn s Handbook of Models for Human Aging

Conn s Handbook of Models for Human Aging
Author: Jeffrey L. Ram,P. Michael Conn
Publsiher: Academic Press
Total Pages: 1218
Release: 2018-04-05
ISBN 10: 0128113545
ISBN 13: 9780128113547
Language: EN, FR, DE, ES & NL

Conn s Handbook of Models for Human Aging Book Review:

Conn's Handbook of Models for Human Aging, Second Edition, presents key aspects of biology, nutrition, factors affecting lifespan, methods of age determination, use in research and the disadvantages/advantages of use. Using a multidisciplinary approach, this updated edition is designed as the only comprehensive, current work that covers the diversity in aging models. Chapters on comparative models explore age-related diseases, including Alzheimer's, joint disease, cataracts, cancer and obesity. Also included are new tricks and approaches not available in primary publications. This must-have handbook is an indispensable resource for researchers interested in the mechanisms of aging, gerontologists, health professionals, allied health practitioners and students. Combines both the methods of study for human aging and animal models Provides a historical overview and discussion of model availability, key methods and ethical issues Contains over 200 full color illustrations

Werner s Syndrome and Human Aging

Werner   s Syndrome and Human Aging
Author: Darrell Salk
Publsiher: Springer Science & Business Media
Total Pages: 656
Release: 2013-03-13
ISBN 10: 1468478532
ISBN 13: 9781468478532
Language: EN, FR, DE, ES & NL

Werner s Syndrome and Human Aging Book Review:

Adult Cognition

Adult Cognition
Author: Timothy A. Salthouse
Publsiher: Springer Science & Business Media
Total Pages: 253
Release: 2012-12-06
ISBN 10: 1461394848
ISBN 13: 9781461394846
Language: EN, FR, DE, ES & NL

Adult Cognition Book Review:

For some time now, the study of cognitive development has been far and away the most active discipline within developmental psychology. Although there would be much disagreement as to the exact proportion of papers published in developmental journals that could be considered cognitive, 50% seems like a conservative estimate. Hence, a series of scholarly books to be devoted to work in cognitive development is especially appropriate at this time. The Springer Series in Cognitive Development contains two basic types of books, namely, edited collections of original chapters by several authors, and original volumes written by one author or a small group of authors. The flagship for the Springer Series is a serial publication of the "advances" type, carrying the subtitle Progress in Cognitive Development Research. Volumes in the Progress sequence are strongly thematic, in that each is limited to some well-defined domain of cognitive-developmental research (e. g. , logical and mathematical development, semantic development). All Progress volumes are edited collections. Editors of such books, upon consultation with the Series Editor, may elect to have their works published either as contributions to the Progress sequence or as separate volumes. All books written by one author or a small group of authors will be published as separate volumes within the series. A fairly broad definition of cognitive development is being used in the selection of books for this series.

Social Policy for an Aging Society

Social Policy for an Aging Society
Author: Carole B. Cox,Carole B. Cox, PhD
Publsiher: Springer Publishing Company
Total Pages: 224
Release: 2015-01-16
ISBN 10: 0826196535
ISBN 13: 9780826196538
Language: EN, FR, DE, ES & NL

Social Policy for an Aging Society Book Review:

As people age, they are at increased risk of having their basic human rights threatened or violated. When age is perceived as incompetence, it can easily lead to discrimination that impacts human rights. Based on the premise that social policy must reflect human rights principles, this graduate-level textbook views the challenges associated with aging as opportunities for policy development that stresses the rights of older adults rather than needs. The text distinguishes between “needs” and “rights” and describes those policies and services that best ensure that the rights of older adults are actually met—particularly programs that enable people to remain in their own communities so they can benefit from continued integration and participation in society. Issues and challenges surrounding such efforts, and gaps in social policies faced by specific subsets of older people, are critically examined. The book first analyzes current aging policies and rights and considers the Older Americans Act as a basic policy framework. With an eye to promoting independence, the book discusses issues of income, housing, transportation, health, and home care and what constitutes a “livable community,” along with policies that promote wellbeing and focus on preventing senior abuse and exploitation. Challenges faced by older workers are covered, as are issues particular to family caregivers, older women, and grandparents as caregivers. Gaps in social policies for LG BT seniors and older members of specific ethnic groups are discussed. Particular attention is given to global issues and aging policies in diverse countries and the ways in which they reflect human rights concerns. Each chapter concludes with probing discussion questions for classroom use. KEY FEATURES: Presents a human rights framework for aging policy Distinguishes between needs and rights of older persons Focuses on policies and programs that can help older people to remain in the community Explores the issues and challenges of specific older populations Discusses global responses and concerns with regard to older persons and human rights Carole B. Cox, MSW, PhD, is professor at the Graduate School of Social Service, Fordham University. She is a fellow of the Gerontological Society of America and a Fulbright scholar. She is the author of more than 50 journal articles and chapters dealing with various aspects of aging and caregiving, with extensive research on caregivers for persons with dementia, their needs, and their use of services. Her recent work includes a study of the impact of dementia on the workplace. Her caregiving research also includes that of grandparents raising grandchildren, leading to the development of a curriculum, Empowering Grandparents Raising Grandchildren: A Training Manual for Group Leaders (Springer Publishing Company, 2000). She is the editor of To Grandmother’s House We Go and Stay: Perspectives on Custodial Grandparents (Springer Publishing Company, 2000). Her other books include Home Care for the Elderly: An International Perspective, coauthored with Abraham Monk (1991); The Frail Elderly: Problems, Needs, and Community Responses (1993); Ethnicity and Social Work Practice, coauthored with Paul Ephross (1998); Community Care for an Aging Society: Policies and Services (Springer Publishing Company, 2005); and Dementia and Social Work Practice (Springer Publishing Company, 2007).

DHEA in Human Health and Aging

DHEA in Human Health and Aging
Author: Ronald Ross Watson
Publsiher: CRC Press
Total Pages: 472
Release: 2011-07-22
ISBN 10: 1439838844
ISBN 13: 9781439838846
Language: EN, FR, DE, ES & NL

DHEA in Human Health and Aging Book Review:

Reduced production of DHEA associated with the diseases that accompany aging has led to its use as a nutritional supplement for antiaging, metabolic support, and other purposes. While animal studies have clearly shown substantial benefits of DHEA in combating various disease states, the effect of low levels of DHEA in humans is less established, an

The Psychology of Human Ageing

The Psychology of Human Ageing
Author: Dennis Basil Bromley,D. B. Bromley
Publsiher: Viking Press
Total Pages: 441
Release: 1978
ISBN 10: 1928374650XXX
ISBN 13: UCAL:B4407655
Language: EN, FR, DE, ES & NL

The Psychology of Human Ageing Book Review:

Ageless

Ageless
Author: Andrew Steele
Publsiher: Doubleday
Total Pages: 352
Release: 2021-03-23
ISBN 10: 0385544936
ISBN 13: 9780385544931
Language: EN, FR, DE, ES & NL

Ageless Book Review:

“A fascinating look at how scientists are working to help doctors treat not just one disease at a time, but the aging process itself.” —Dr. Sanjay Gupta A startling chronicle by a brilliant young scientist takes us onto the frontiers of the science of aging, and reveals how close we are to an astonishing extension of our life spans and a vastly improved quality of life in our later years. Aging--not cancer, not heart disease--is the true underlying cause of most human death and suffering. We accept as inevitable that as we advance in years our bodies and minds begin to deteriorate and that we are ever more likely to be felled by dementia or disease. But we never really ask--is aging necessary? Biologists, on the other hand, have been investigating that question for years. After all, there are tortoises and salamanders whose risk of dying is the same no matter how old they are. With the help of science, could humans find a way to become old without getting frail, a phenomenon known as "biological immortality"? In Ageless, Andrew Steele, a computational biologist and science writer, takes us on a journey through the laboratories where scientists are studying every bodily system that declines with age--DNA, mitochondria, stem cells, our immune systems--and developing therapies to reverse the trend. With bell-clear writing and intellectual passion, Steele shines a spotlight on a little-known revolution already underway.