Process Systems Engineering for Pharmaceutical Manufacturing

Process Systems Engineering for Pharmaceutical Manufacturing
Author: Ravendra Singh,Zhihong Yuan
Publsiher: Elsevier
Total Pages: 698
Release: 2018-03-16
ISBN 10: 0444639667
ISBN 13: 9780444639660
Language: EN, FR, DE, ES & NL

Process Systems Engineering for Pharmaceutical Manufacturing Book Review:

Process Systems Engineering for Pharmaceutical Manufacturing: From Product Design to Enterprise-Wide Decisions, Volume 41, covers the following process systems engineering methods and tools for the modernization of the pharmaceutical industry: computer-aided pharmaceutical product design and pharmaceutical production processes design/synthesis; modeling and simulation of the pharmaceutical processing unit operation, integrated flowsheets and applications for design, analysis, risk assessment, sensitivity analysis, optimization, design space identification and control system design; optimal operation, control and monitoring of pharmaceutical production processes; enterprise-wide optimization and supply chain management for pharmaceutical manufacturing processes. Currently, pharmaceutical companies are going through a paradigm shift, from traditional manufacturing mode to modernized mode, built on cutting edge technology and computer-aided methods and tools. Such shifts can benefit tremendously from the application of methods and tools of process systems engineering. Introduces Process System Engineering (PSE) methods and tools for discovering, developing and deploying greener, safer, cost-effective and efficient pharmaceutical production processes Includes a wide spectrum of case studies where different PSE tools and methods are used to improve various pharmaceutical production processes with distinct final products Examines the future benefits and challenges for applying PSE methods and tools to pharmaceutical manufacturing

Continuous Manufacturing of Pharmaceuticals

Continuous Manufacturing of Pharmaceuticals
Author: Peter Kleinebudde,Johannes Khinast,Jukka Rantanen
Publsiher: John Wiley & Sons
Total Pages: 620
Release: 2017-09-05
ISBN 10: 1119001323
ISBN 13: 9781119001324
Language: EN, FR, DE, ES & NL

Continuous Manufacturing of Pharmaceuticals Book Review:

10.7.3 State of Control

Continuous Pharmaceutical Processing

Continuous Pharmaceutical Processing
Author: Zoltan K Nagy,Arwa El Hagrasy,Jim Litster
Publsiher: Springer Nature
Total Pages: 541
Release: 2020-06-10
ISBN 10: 3030415244
ISBN 13: 9783030415242
Language: EN, FR, DE, ES & NL

Continuous Pharmaceutical Processing Book Review:

Continuous pharmaceutical manufacturing is currently receiving much interest from industry and regulatory authorities, with the joint aim of allowing rapid access of novel therapeutics and existing medications to the public, without compromising high quality. Research groups from different academic institutions have significantly contributed to this field with an immense amount of published research addressing a variety of topics related to continuous processing. The book is structured to have individual chapters on the different continuous unit operations involved in drug substance and drug product manufacturing. A wide spectrum of topics are covered, including basic principles of continuous manufacturing, applications of continuous flow chemistry in drug synthesis, continuous crystallization, continuous drying, feeders and blenders, roll compaction and continuous wet granulation.The underlying theme for each of these chapters is to present to the reader the recent advances in modeling, experimental investigations and equipment design as they pertain to each individual unit operation. The book also includes chapters on quality by design (QbD) and process analytical technology (PAT) for continuous processing, process control strategies including new concepts of quality-by-control (QbC), real-time process management and plant optimization, business and supply chain considerations related to continuous manufacturing as well as safety guidelines related to continuous chemistry. A separate chapter is dedicated to discussing regulatory aspects of continuous manufacturing, with description of current regulatory environment quality/GMP aspects, as well as regulatory gaps and challenges. Our aim from publishing this book is to make it a valuable reference for readers interested in this topic, with a desire to gain a fundamental understanding of engineering principles and mechanistic studies utilized in understanding and developing continuous processes. In addition, our advanced readers and practitioners in this field will find that the technical content of Continuous Pharmaceutical Processing is at the forefront of recent technological advances, with coverage of future prospects and challenges for this technology.

Pharmaceutical Blending and Mixing

Pharmaceutical Blending and Mixing
Author: P. J. Cullen,Rodolfo J. Romañach,Nicolas Abatzoglou,Chris D. Rielly
Publsiher: John Wiley & Sons
Total Pages: 512
Release: 2015-05-11
ISBN 10: 1118683455
ISBN 13: 9781118683453
Language: EN, FR, DE, ES & NL

Pharmaceutical Blending and Mixing Book Review:

Written in four parts, this book provides a dedicated and in-depth reference for blending within the pharmaceutical manufacturing industry. It links the science of blending with regulatory requirements associated with pharmaceutical manufacture. The contributors are a combination of leading academic and industrial experts, who provide an informed and industrially relevant perspective of the topic. This is an essential book for the pharmaceutical manufacturing industry, and related academic researchers in pharmaceutical science and chemical and mechanical engineering.

Handbook of Pharmaceutical Wet Granulation

Handbook of Pharmaceutical Wet Granulation
Author: Ajit S. Narang,Sherif I.F. Badawy
Publsiher: Academic Press
Total Pages: 890
Release: 2018-08-31
ISBN 10: 0323481035
ISBN 13: 9780323481038
Language: EN, FR, DE, ES & NL

Handbook of Pharmaceutical Wet Granulation Book Review:

Handbook of Pharmaceutical Wet Granulation: Theory and Practice in a Quality by Design Paradigm offers a single and comprehensive reference dedicated to all aspects of pharmaceutical wet granulation, taking a holistic approach by combining introductory principles with practical solutions. Chapters are written by international experts across industry, academic and regulatory settings, and cover a wide spectrum of relevant and contemporary wet granulation topics, techniques and processes. The books' focus on process analytical technology, quality by design principles, granulation equipment, modeling, scale-up, control and real time release makes it a timely and valuable resource for all those involved in pharmaceutical wet granulation. Discusses fundamentals of theory and current industrial practice in the field of wet granulation, including product and process design and role of material properties in wet granulation Examines the modern evolution of wet granulation through current topics such as established and novel process analytical technologies (PATs), and product development and scale-up paradigms Written for scientists working within the pharmaceutical industry, as well as academics, regulatory officials and equipment vendors who provide PAT tools and granulation equipment

Pharmaceutical Manufacturing Handbook

Pharmaceutical Manufacturing Handbook
Author: Shayne Cox Gad
Publsiher: John Wiley & Sons
Total Pages: 1384
Release: 2008-03-21
ISBN 10: 0470259809
ISBN 13: 9780470259801
Language: EN, FR, DE, ES & NL

Pharmaceutical Manufacturing Handbook Book Review:

This handbook features contributions from a team of expert authors representing the many disciplines within science, engineering, and technology that are involved in pharmaceutical manufacturing. They provide the information and tools you need to design, implement, operate, and troubleshoot a pharmaceutical manufacturing system. The editor, with more than thirty years' experience working with pharmaceutical and biotechnology companies, carefully reviewed all the chapters to ensure that each one is thorough, accurate, and clear.

21st European Symposium on Computer Aided Process Engineering

21st European Symposium on Computer Aided Process Engineering
Author: Anonim
Publsiher: Elsevier
Total Pages: 2082
Release: 2011-06-10
ISBN 10: 0444538968
ISBN 13: 9780444538963
Language: EN, FR, DE, ES & NL

21st European Symposium on Computer Aided Process Engineering Book Review:

The European Symposium on Computer Aided Process Engineering (ESCAPE) series presents the latest innovations and achievements of leading professionals from the industrial and academic communities. The ESCAPE series serves as a forum for engineers, scientists, researchers, managers and students to present and discuss progress being made in the area of computer aided process engineering (CAPE). European industries large and small are bringing innovations into our lives, whether in the form of new technologies to address environmental problems, new products to make our homes more comfortable and energy efficient or new therapies to improve the health and well being of European citizens. Moreover, the European Industry needs to undertake research and technological initiatives in response to humanity's "Grand Challenges," described in the declaration of Lund, namely, Global Warming, Tightening Supplies of Energy, Water and Food, Ageing Societies, Public Health, Pandemics and Security. Thus, the Technical Theme of ESCAPE 21 will be "Process Systems Approaches for Addressing Grand Challenges in Energy, Environment, Health, Bioprocessing & Nanotechnologies."

The Chemical Engineer

The Chemical Engineer
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1997
ISBN 10:
ISBN 13: UOM:39015040321963
Language: EN, FR, DE, ES & NL

The Chemical Engineer Book Review:

Handbook of Pharmaceutical Manufacturing Formulations

Handbook of Pharmaceutical Manufacturing Formulations
Author: Safaraz K. Niazi
Publsiher: CRC Press
Total Pages: 464
Release: 2016-04-19
ISBN 10: 1420081314
ISBN 13: 9781420081312
Language: EN, FR, DE, ES & NL

Handbook of Pharmaceutical Manufacturing Formulations Book Review:

No other area of regulatory compliance receives more attention and scrutiny by regulatory authorities than the regulation of sterile products, for obvious reasons. With the increasing number of potent products, particularly the new line of small protein products, joining the long list of proven sterile products, the technology of manufacturing ster

Formulation and Analytical Development for Low Dose Oral Drug Products

Formulation and Analytical Development for Low Dose Oral Drug Products
Author: Jack Zheng
Publsiher: John Wiley & Sons
Total Pages: 496
Release: 2009-02-09
ISBN 10: 0470056096
ISBN 13: 9780470056097
Language: EN, FR, DE, ES & NL

Formulation and Analytical Development for Low Dose Oral Drug Products Book Review:

There are unique challenges in the formulation, manufacture, analytical chemistry, and regulatory requirements of low-dose drugs. This book provides an overview of this specialized field and combines formulation, analytical, and regulatory aspects of low-dose development into a single reference book. It describes analytical methodologies like dissolution testing, solid state NMR, Raman microscopy, and LC-MS and presents manufacturing techniques such as granulation, compaction, and compression. Complete with case studies and a discussion of regulatory requirements, this is a core reference for pharmaceutical scientists, regulators, and graduate students.

Melt Extrusion

Melt Extrusion
Author: Michael A. Repka,Nigel Langley,James DiNunzio
Publsiher: Springer Science & Business Media
Total Pages: 474
Release: 2013-10-11
ISBN 10: 1461484324
ISBN 13: 9781461484325
Language: EN, FR, DE, ES & NL

Melt Extrusion Book Review:

This volume provides readers with the basic principles and fundamentals of extrusion technology and a detailed description of the practical applications of a variety of extrusion processes, including various pharma grade extruders. In addition, the downstream production of films, pellets and tablets, for example, for oral and other delivery routes, are presented and discussed utilizing melt extrusion. This book is the first of its kind that discusses extensively the well-developed science of extrusion technology as applied to pharmaceutical drug product development and manufacturing. By covering a wide range of relevant topics, the text brings together all technical information necessary to develop and market pharmaceutical dosage forms that meet current quality and regulatory requirements. As extrusion technology continues to be refined further, usage of extruder systems and the array of applications will continue to expand, but the core technologies will remain the same.

Advances in Sustainable and Competitive Manufacturing Systems

Advances in Sustainable and Competitive Manufacturing Systems
Author: Américo Azevedo
Publsiher: Springer Science & Business Media
Total Pages: 1693
Release: 2013-06-25
ISBN 10: 331900557X
ISBN 13: 9783319005577
Language: EN, FR, DE, ES & NL

Advances in Sustainable and Competitive Manufacturing Systems Book Review:

The proceedings includes the set of revised papers from the 23rd International Conference on Flexible Automation and Intelligent Manufacturing (FAIM 2013). This conference aims to provide an international forum for the exchange of leading edge scientific knowledge and industrial experience regarding the development and integration of the various aspects of Flexible Automation and Intelligent Manufacturing Systems covering the complete life-cycle of a company’s Products and Processes. Contents will include topics such as: Product, Process and Factory Integrated Design, Manufacturing Technology and Intelligent Systems, Manufacturing Operations Management and Optimization and Manufacturing Networks and MicroFactories.

Power System Energy Storage Technologies

Power System Energy Storage Technologies
Author: Paul Breeze
Publsiher: Academic Press
Total Pages: 100
Release: 2018-05-16
ISBN 10: 0128129034
ISBN 13: 9780128129036
Language: EN, FR, DE, ES & NL

Power System Energy Storage Technologies Book Review:

Power System Energy Storage Technologies provides a comprehensive analysis of the various technologies used to store electrical energy on both a small and large scale. Although expensive to implement, energy storage plants can offer significant benefits for the generation, distribution and use of electrical power. This is particularly important in renewable energy, which is intermittent in its supply. This book provides coverage of major technologies, such as sections on Pumped Storage Hydropower, Compressed-Air Energy Storage, Large Scale Batteries and Superconducting Magnetic Energy Storage, each of which is presented with discussions of their operation, performance, efficiency and the costs associated with implementation and management. Provides a description and analysis of various storage technologies, such as Pumped Storage Hydropower, Compressed-Air Energy Storage, Large Scale Batteries and Superconducting Magnetic Energy Storage Breaks down each storage type and analyzes their operation, performance, efficiency and costs Considers how each energy storage plant benefits the generation distribution and use of electric power

Production Handling and Characterization of Particulate Materials

Production  Handling and Characterization of Particulate Materials
Author: Henk G. Merkus,Gabriel M.H. Meesters
Publsiher: Springer
Total Pages: 548
Release: 2015-11-26
ISBN 10: 3319209493
ISBN 13: 9783319209494
Language: EN, FR, DE, ES & NL

Production Handling and Characterization of Particulate Materials Book Review:

This edited volume presents most techniques and methods that have been developed by material scientists, chemists, chemical engineers and physicists for the commercial production of particulate materials, ranging from the millimeter to the nanometer scale. The scope includes the physical and chemical background, experimental optimization of equipment and procedures, as well as an outlook on future methods. The books addresses issues of industrial importance such as specifications, control parameter(s), control strategy, process models, energy consumption and discusses the various techniques in relation to potential applications. In addition to the production processes, all major unit operations and characterization methods are described in this book. It differs from other books which are devoted to a single technique or a single material. Contributors to this book are acknowledged experts in their field. The aim of the book is to facilitate comparison of the different unit operations leading to optimum equipment choices for the production, handling and storage of particulate materials. An advantage of this approach is that unit operations that are common in one field of application are made accessible to other fields. The overall focus is on industrial application and the book includes some concrete examples. The book is an essential resource for students or researchers who work in collaboration with manufacturing industries or who are planning to make the switch from academia to industry.

Pharmaceutical Quality Systems

Pharmaceutical Quality Systems
Author: Oliver Schmidt
Publsiher: CRC Press
Total Pages: 392
Release: 2000-04-30
ISBN 10: 142002602X
ISBN 13: 9781420026023
Language: EN, FR, DE, ES & NL

Pharmaceutical Quality Systems Book Review:

When a pharmaceutical company decides to build a Quality System, it has to face the fact that there aren't any guideline that define exactly how such a system has to be built. With terms such as quality system, quality assurance, and quality management used interchangeably, even defining the system's objectives is a problem. This book provides a pr

Unit Manufacturing Processes

Unit Manufacturing Processes
Author: National Research Council,Division on Engineering and Physical Sciences,Board on Manufacturing and Engineering Design,Commission on Engineering and Technical Systems,Unit Manufacturing Process Research Committee
Publsiher: National Academies Press
Total Pages: 228
Release: 1995-01-03
ISBN 10: 9780309176675
ISBN 13: 0309176670
Language: EN, FR, DE, ES & NL

Unit Manufacturing Processes Book Review:

Manufacturing, reduced to its simplest form, involves the sequencing of product forms through a number of different processes. Each individual step, known as an unit manufacturing process, can be viewed as the fundamental building block of a nation's manufacturing capability. A committee of the National Research Council has prepared a report to help define national priorities for research in unit processes. It contains an organizing framework for unit process families, criteria for determining the criticality of a process or manufacturing technology, examples of research opportunities, and a prioritized list of enabling technologies that can lead to the manufacture of products of superior quality at competitive costs. The study was performed under the sponsorship of the National Science Foundation and the Defense Department's Manufacturing Technology Program.

Polymer Science and Engineering

Polymer Science and Engineering
Author: National Research Council,Division on Engineering and Physical Sciences,Commission on Physical Sciences, Mathematics, and Applications,Committee on Polymer Science and Engineering
Publsiher: National Academies Press
Total Pages: 192
Release: 1994-01-01
ISBN 10: 0309049989
ISBN 13: 9780309049986
Language: EN, FR, DE, ES & NL

Polymer Science and Engineering Book Review:

Polymers are used in everything from nylon stockings to commercial aircraft to artificial heart valves, and they have a key role in addressing international competitiveness and other national issues. Polymer Science and Engineering explores the universe of polymers, describing their properties and wide-ranging potential, and presents the state of the science, with a hard look at downward trends in research support. Leading experts offer findings, recommendations, and research directions. Lively vignettes provide snapshots of polymers in everyday applications. The volume includes an overview of the use of polymers in such fields as medicine and biotechnology, information and communication, housing and construction, energy and transportation, national defense, and environmental protection. The committee looks at the various classes of polymers--plastics, fibers, composites, and other materials, as well as polymers used as membranes and coatings--and how their composition and specific methods of processing result in unparalleled usefulness. The reader can also learn the science behind the technology, including efforts to model polymer synthesis after nature's methods, and breakthroughs in characterizing polymer properties needed for twenty-first-century applications. This informative volume will be important to chemists, engineers, materials scientists, researchers, industrialists, and policymakers interested in the role of polymers, as well as to science and engineering educators and students.

24th European Symposium on Computer Aided Process Engineering

24th European Symposium on Computer Aided Process Engineering
Author: Anonim
Publsiher: Elsevier
Total Pages: 1954
Release: 2014-06-20
ISBN 10: 0444634436
ISBN 13: 9780444634436
Language: EN, FR, DE, ES & NL

24th European Symposium on Computer Aided Process Engineering Book Review:

The 24th European Symposium on Computer Aided Process Engineering creates an international forum where scientific and industrial contributions of computer-aided techniques are presented with applications in process modeling and simulation, process synthesis and design, operation, and process optimization. The organizers have broadened the boundaries of Process Systems Engineering by inviting contributions at different scales of modeling and demonstrating vertical and horizontal integration. Contributions range from applications at the molecular level to the strategic level of the supply chain and sustainable development. They cover major classical themes, at the same time exploring a new range of applications that address the production of renewable forms of energy, environmental footprints and sustainable use of resources and water.

Cooking for Geeks

Cooking for Geeks
Author: Jeff Potter
Publsiher: "O'Reilly Media, Inc."
Total Pages: 432
Release: 2010-07-20
ISBN 10: 1449396038
ISBN 13: 9781449396039
Language: EN, FR, DE, ES & NL

Cooking for Geeks Book Review:

Presents recipes ranging in difficulty with the science and technology-minded cook in mind, providing the science behind cooking, the physiology of taste, and the techniques of molecular gastronomy.

Importing Into the United States

Importing Into the United States
Author: United States Customs Service
Publsiher: The Minerva Group, Inc.
Total Pages: 132
Release: 2002-06
ISBN 10: 9780894990779
ISBN 13: 0894990772
Language: EN, FR, DE, ES & NL

Importing Into the United States Book Review:

This publication provides an overview of the importing process and contains general information about import requirements. This edition contains much new and revised material brought about because of changes in the law, particularly the Customs Modernization Act. The Customs modernization provisions has fundamentally altered the process by shifting to the importer the legal responsibility for declaring the value, classification, and rate of duty applicable to entered merchandise.Chapters cover entry of goods, informed compliance, invoices, assessment of duty, classification and value, marking, special requirements for alcoholic beverages, motor vehicles and boats, import quotas, fraud, and foreign trade zones.In addition to the material provided by the U. S. Customs Service, the private commercial publisher of this book has provided a bonus chapter on how to build a tax-free import-export business.