Hematopoietic Cell Transplantation for Malignant Conditions

Hematopoietic Cell Transplantation for Malignant Conditions
Author: Qaiser Bashir,Mehdi Hamadani
Publsiher: Elsevier Health Sciences
Total Pages: 438
Release: 2019-02-14
ISBN 10: 0323568033
ISBN 13: 9780323568036
Language: EN, FR, DE, ES & NL

Hematopoietic Cell Transplantation for Malignant Conditions Book Review:

Get a quick, expert overview of hematologic and non-hematologic malignancies for which hematopoietic cell transplantation is a treatment option. Drs. Qaiser Bashir and Mehdi Hamadani provide easy-to-find information on basic science of hematopoietic cell transplantation, pharmacology, workflows and procedures, possible complications and side effects, in addition to the role of HCT in conjunction with clinical cellular therapy. Discusses high-dose chemotherapeutic regimens and radiation therapy, patient and donor selection and workup, as well as other key aspects of hematopoietic cell transplantation. Includes practical information on complications, infectious disease, and special populations such as patients with HIV infection. Consolidates today’s available information in this fast-changing area into one convenient resource.

Hematopoietic Stem Cell Transplantation in Clinical Practice

Hematopoietic Stem Cell Transplantation in Clinical Practice
Author: Jennifer G. Treleaven,A. John Barrett
Publsiher: Elsevier Health Sciences
Total Pages: 568
Release: 2008-09-02
ISBN 10: 0702033537
ISBN 13: 9780702033537
Language: EN, FR, DE, ES & NL

Hematopoietic Stem Cell Transplantation in Clinical Practice Book Review:

A guide to the practice of stem cell transplantation, its status in the treatment of various disorders and the problems that arise after transplantation, aimed at the whole transplant team. An up to date guide to best practice in the use of stem cell transplantation, covering current status in the treatment of malignant and non-malignant conditions, practical aspects and problems such as infection and graft versus host disease. Has a practical, accessible approach with free use of algorithms, list tables. Aimed at the whole transplant team - this is an interdisciplinary field. International contributor team with editors in the UK and USA. Illustrated in colour throughout.

Stem Cell Transplantation for Hematologic Malignancies

Stem Cell Transplantation for Hematologic Malignancies
Author: Robert J. Soiffer
Publsiher: Springer Science & Business Media
Total Pages: 486
Release: 2004-01-29
ISBN 10: 1592597335
ISBN 13: 9781592597338
Language: EN, FR, DE, ES & NL

Stem Cell Transplantation for Hematologic Malignancies Book Review:

A comprehensive survey of the current state-of-the-art in hematopoietic stem cell transplantation for malignant disease. The authors focus on the indications and results of transplantation for acute leukemia, chronic myelogenous leukemia, lymphoma, multiple myeloma, and breast cancer. Special attention is given to transplant-related complications, including the pathophysiology and clinical consequences of acute and chronic GVHD, delayed immune reconstitution leading to infectious complications, and organ damage to the lung and liver. Additional chapters address the sources of stem cells and the effects of graft manipulation used to eliminate residual contaminating tumor cells in autologous transplantation, or to reduce the number of T lymphocytes causing GVHD in allogenic transplantation.

Thomas Hematopoietic Cell Transplantation

Thomas  Hematopoietic Cell Transplantation
Author: Stephen J. Forman,Robert S. Negrin,Joseph H. Antin,Frederick R. Appelbaum
Publsiher: John Wiley & Sons
Total Pages: 1416
Release: 2015-12-14
ISBN 10: 1118416120
ISBN 13: 9781118416129
Language: EN, FR, DE, ES & NL

Thomas Hematopoietic Cell Transplantation Book Review:

Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

Thomas Hematopoietic Cell Transplantation

Thomas  Hematopoietic Cell Transplantation
Author: Karl G. Blume,Stephen J. Forman,Frederick R. Appelbaum
Publsiher: John Wiley & Sons
Total Pages: 1600
Release: 2008-04-15
ISBN 10: 1405140119
ISBN 13: 9781405140119
Language: EN, FR, DE, ES & NL

Thomas Hematopoietic Cell Transplantation Book Review:

NEW - the leading book in its field now fully updated and revised! Click here to access two FREE sample chapters! An Essential resource for all hematologists, oncologists, pathologists, pediatricians, immunologists and all others interested in this dynamic area of medicine! Why you should buy this book.... Extensive coverage of subject area - from the scientific basis to the view of the future Includes all experimental research and clinical application Combined the knowledge and expertise of over 170 international specialists Clear structure and layout Over 500 illustrations, including a colour plate section Why buy the NEW edition...... New and fully revised to reflect the latest developments in this fast moving field 10 new chapters, covering some of the latest developments - see below for the complete tables of content

The European Blood and Marrow Transplantation Textbook for Nurses

The European Blood and Marrow Transplantation Textbook for Nurses
Author: Michelle Kenyon,Aleksandra Babic
Publsiher: Springer
Total Pages: 311
Release: 2018-03-14
ISBN 10: 3319500260
ISBN 13: 9783319500263
Language: EN, FR, DE, ES & NL

The European Blood and Marrow Transplantation Textbook for Nurses Book Review:

This book is open access under a CC BY 4.0 license. This textbook, endorsed by the European Society for Blood and Marrow Transplantation (EBMT), provides adult and paediatric nurses with a full and informative guide covering all aspects of transplant nursing, from basic principles to advanced concepts. It takes the reader on a journey through the history of transplant nursing, including essential and progressive elements to help nurses improve their knowledge and benefit the patient experience, as well as a comprehensive introduction to research and auditing methods. This new volume specifically intended for nurses, complements the ESH-EBMT reference title, a popular educational resource originally developed in 2003 for physicians to accompany an annual training course also serving as an educational tool in its own right. This title is designed to develop the knowledge of nurses in transplantation. It is the first book of its kind specifically targeted at nurses in this specialist field and acknowledges the valuable contribution that nursing makes in this area. This volume presents information that is essential for the education of nurses new to transplantation, while also offering a valuable resource for more experienced nurses who wish to update their knowledge.

Mycophenolate Mofetil Pharmacology and Bioavailability in Hematopoietic Cell Transplantation for Malignant Diseases

Mycophenolate Mofetil Pharmacology and Bioavailability in Hematopoietic Cell Transplantation for Malignant Diseases
Author: Kathleen Germaine Evans Green
Publsiher: Unknown
Total Pages: 104
Release: 2005
ISBN 10: 1928374650XXX
ISBN 13: OCLC:72869295
Language: EN, FR, DE, ES & NL

Mycophenolate Mofetil Pharmacology and Bioavailability in Hematopoietic Cell Transplantation for Malignant Diseases Book Review:

Hematopoietic Cell Transplantation in Children with Cancer

Hematopoietic Cell Transplantation in Children with Cancer
Author: Franklin O. Smith,Gregory H. Reaman,Judy M. Racadio
Publsiher: Springer Science & Business Media
Total Pages: 358
Release: 2013-11-26
ISBN 10: 3642399207
ISBN 13: 9783642399206
Language: EN, FR, DE, ES & NL

Hematopoietic Cell Transplantation in Children with Cancer Book Review:

This book is a comprehensive and up-to-date compendium on all aspects of blood and marrow transplantation in children. After an introductory chapter describing the history of pediatric blood and marrow transplantation, subsequent chapters discuss pediatric-specific aspects of transplantation, including stem cell sources suitable for transplantation, preparative regimens, graft-versus-host disease, complications related to transplantation, and late effects. The role of blood and marrow transplantation in various specific pediatric diseases is then examined, and the closing chapter considers future directions. The authors are all internationally recognized experts and offer a largely evidence-based consensus on etiology, biology, and treatment. This handbook has far-reaching applicability to the clinical diagnosis and management of pediatric diseases that are treatable with blood and marrow transplantation and will prove invaluable to specialists, generalists, and trainees alike.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
Author: Robert J. Soiffer
Publsiher: Springer Science & Business Media
Total Pages: 736
Release: 2008-11-14
ISBN 10: 9781597454384
ISBN 13: 1597454389
Language: EN, FR, DE, ES & NL

Hematopoietic Stem Cell Transplantation Book Review:

Remarkable developments in the field of transplantation have created opportunities to address the formidable challenges of transplantation across histocompatibility barriers, stem cell expansion, and prevention of complications and generation of graft-vs-tumor activity to eradicate residual disease. Stem Cell Transplantation for Hematologic and Other Disorders, Second Edition provides a glimpse into potential future applications of bone marrow derived stem cells in the field of cardiac repair. The updated chapters introduce the biologic underpinnings of hematopoietic cell transplantation, basic stem cell biology, immunobiology, and histocompatibility, with emphasis on indications and results of transplantation for specific diseases. Written by experts in the field, Stem Cell Transplantation for Hematologic Disorders, Second Edition provides seasoned professionals with a complete understanding of the current state of transplantation biology as well as a clear vision into the future.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
Author: Jennifer Treleaven,Austin John Barrett
Publsiher: Churchill Livingstone
Total Pages: 555
Release: 2009
ISBN 10: 9780443101472
ISBN 13: 0443101477
Language: EN, FR, DE, ES & NL

Hematopoietic Stem Cell Transplantation Book Review:

A guide to the practice of stem cell transplantation, its status in the treatment of various disorders and the problems that arise after transplantation, aimed at the whole transplant team. An up to date guide to best practice in the use of stem cell transplantation, covering current status in the treatment of malignant and non-malignant conditions, practical aspects and problems such as infection and graft versus host disease. Has a practical, accessible approach with free use of algorithms, list tables. Aimed at the whole transplant team - this is an interdisciplinary field. International contributor team with editors in the UK and USA. Illustrated in colour throughout.

Allogeneic Immunotherapy for Malignant Diseases

Allogeneic Immunotherapy for Malignant Diseases
Author: John Barrett,Yin-Zhen Jiang
Publsiher: CRC Press
Total Pages: 408
Release: 2000-01-27
ISBN 10: 9780824746766
ISBN 13: 0824746767
Language: EN, FR, DE, ES & NL

Allogeneic Immunotherapy for Malignant Diseases Book Review:

This important reference offers a comprehensive review of the graft-versus-leukemia (GVL) or -tumor (GVT) effect following allogeneic stem cell transplantation and lymphocyte transfusion, covering a wide range of topics from alloimmune responses to clinical applications of GVL, and providing the basics to understand the mechanisms of the GVL effect while demonstrating methods that use the GVL effect to cure a greater number of cancer patients. Presents preliminary data supporting the idea that allogeneic cell therapy can be used not only for the treatment of leukemia but also for metastatic solid tumors! Written by over 40 world renowned experts in the field and containing more than 1450 references for in-depth exploration of the subject, Allogeneic Immunotherapy for Malignant Diseases investigates the capacity of the donor-and the host-to destroy residual leukemia cells by allogeneic immune reaction determines how to direct immune reactions against hematopoietic malignancies safely reveals which other malignant conditions may be responsive to allogeneic-mediated graft-versus-tumor reactions covers the mechanisms that contribute to the development of responses to minor histocompatibility complex (mHC) molecules focuses on the biology of effector cells and their role in mediating GVL reactions in chronic myeloid leukemia (CML) summarizes the putative impact of human mHag on the GVL effect in bone marrow transplantation (BMT) addresses the potential and limitations of oncogene-based immunotherapy examines ways to isolate and control the GVL component of allograft immunity discusses efforts to develop specific anti-leukemic T-cell immunotherapy and more! Attributing the curative effect of allogeneic stem cell transplantation to the GVL or GVT effect, Allogeneic Immunotherapy for Malignant Diseases is an indispensable reference for hematologists, clinical oncologists, immunologists and researchers in the fields of tumor immunology and cancer immunotherapy, internists, residents, and medical school students in these disciplines.

Hematopoietic Stem Cell Transplantation

Hematopoietic Stem Cell Transplantation
Author: Michael R. Bishop
Publsiher: Springer Science & Business Media
Total Pages: 589
Release: 2009-09-25
ISBN 10: 9780387785806
ISBN 13: 0387785809
Language: EN, FR, DE, ES & NL

Hematopoietic Stem Cell Transplantation Book Review:

The dogmas of the quiet past are inadequate to the stormy present. The occasion is piled high with difficulty, and we must rise with the occasion. As our case is new, so we must think anew and act anew. Abraham Lincoln, 1862 When I came across this quote, it made me recall my first participation at an international meeting on bone marrow transplantation, at a time when this was the only term that was used to describe the field. During a particular session there was a presentation on the use of peripheral blood as the sole source of stem cells for transplantation, and a member of the audience rose to state that it was medically unethical to consider such treatment, as it certainly could not contain stem cells. Now nearly twenty years later, peripheral blood is the predominant source of stem cells used for hematopoietic stem cell transplantation. In the same period of time there have been several other dogmatic opinions, which permeate all of medicine, that have come and gone in the field of hematopoietic stem cell transplantation, and will continue to do so with advancements from basic and clinical research. It is within this context that the format of this book was devised. Traditionally reviews on specific topics related to hematopoietic stem cell transplantation reflect the views of a single author or a research group.

Establishing a Hematopoietic Stem Cell Transplantation Unit

Establishing a Hematopoietic Stem Cell Transplantation Unit
Author: Éliane Gluckman,Dietger Niederwieser,Mahmoud Aljurf
Publsiher: Springer
Total Pages: 306
Release: 2017-11-17
ISBN 10: 3319593587
ISBN 13: 9783319593586
Language: EN, FR, DE, ES & NL

Establishing a Hematopoietic Stem Cell Transplantation Unit Book Review:

This text aims to provide simplified practical guidelines to start a hematopoietic stem cell transplantation unit which could be implemented in most centers and countries worldwide. The book also provides guidelines for existing transplantation units to upgrade their practice and implement new policies and procedures, in addition to developing therapies according to latest international standards and regulations. The book covers a wide range of practical implementation tools including HSCT program team structure, building inpatient and outpatient HSCT units, requisite laboratory support for transplantation program, practical aspects of stem cell collection and processing, HSCT program quality management, education and training, and data management. The book also addresses cost effectiveness and recommendations for establishing transplantation program in countries with limited resources. Written by group of internationally established experts in their corresponding hematopoietic stem cell transplantation fields, with contributions from many leaders of hematopoietic stem cell transplantation organizations, Establishing a Hematopoietic Stem Cell Transplantation Unit: A Practical Guide is an essential, practical resource for all members of the multidisciplinary hematopoietic stem cell transplantation team.

Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy An Issue of Infectious Disease Clinics of North America Ebook

Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy  An Issue of Infectious Disease Clinics of North America  Ebook
Author: Jo-Anne Young
Publsiher: Elsevier Health Sciences
Total Pages: 135
Release: 2019-06-28
ISBN 10: 0323678734
ISBN 13: 9780323678735
Language: EN, FR, DE, ES & NL

Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy An Issue of Infectious Disease Clinics of North America Ebook Book Review:

In collaboration with Consulting Editor, Dr. Helen Boucher, Dr. Jo-Ann Young has put together a state-of the-art issue of the Infectious Disease Clinics of North America devoted to Management of Infectious Diseases in Stem Cell Transplantation and Hematologic Malignancy. Clinical review articles from expert authors are specifically devoted to the following topics, addressing both the stem cell transplant recipient and the hematologic malignancy patient: Chemotherapy Regimens for Hematologic Malignancies and Issues That Affect Infection; Stem Cell Transplantation Technical Issues That Affect Infection in The Recipient; Complications of Stem Cell Transplantation That Cause Infections; Antimicrobial Prophylaxis and Preemptive Agents and Regimens for the Prevention of Infection; Workup for Fever During Neutropenia; Herpesvirus Infections; Cytomegalovirus Infections; Respiratory Virus Infections; Other DNA Virus Infections; Bacterial Infections; Fungal Infections; Parasitic Infections; Vaccination; and Immunoglobulin Replacement. Readers will come away with the latest information they need to manage infections and improve outcomes in these patients.

Blood Stem Cell Transplantation

Blood Stem Cell Transplantation
Author: Jane N. Winter
Publsiher: Springer Science & Business Media
Total Pages: 416
Release: 2012-12-06
ISBN 10: 1461563496
ISBN 13: 9781461563495
Language: EN, FR, DE, ES & NL

Blood Stem Cell Transplantation Book Review:

Blood Stem Cell Transplantation conveys the excitement that accompanies the newest developments in hematopoietic stem cell transplantation. Some of the applications that stand to impact this field most significantly are based on recent advances in the biological sciences, as demonstrated by the chapters on gene therapy, on the detection of minimal residual disease using molecular techniques, and on the use of radioimmunoconjugates targeting lymphoma and leukemia-associated antigens. Others are the results of clinical observations - e.g., the association between graft-versus-host- disease (GVHD) and durable remissions that have led to creative clinical experiments such as donor leukocyte infusions (DLI). Attempts to unravel the biological events that underlie the responses seen in patients with relapsed chronic myelogenous leukemia treated with DLI are likely to provide the basis for future refinements in this clinical approach. Hopefully, improved response rates and reduced toxicity will result. The power of the immunologic response in controlling malignant disease is underscored in the chapter on post-transplant immunotherapy. The complex immunologic process that results in clinical GVHD may be dissected and engineered to provide clinical benefits that include, in addition to its antineoplastic effects, the amelioration of its clinical manifestations. Better control of GVHD with less global immunosuppression will facilitate the use of mismatched and unrelated donors. This area of investigation perfectly illustrates the continued interplay between the laboratory and the clinic. The continued cross-fertilization of ideas between immunologists, molecular biologists and clinical investigators is likely to yield important advances in this field for years to come. Possible applications of stem cell transplantation continue to grow with the identification of alternative sources of stem cells and the potential to engineer and/or expand the graft. Although the use of unrelated and mismatched donors continues to increase, the possibilities associated with umbilical cord blood transplantation are legion, especially if stem cells can be expanded ex vivo to provide grafts for full-sized adults. Using techniques in which contaminating malignant cells may be eliminated from autografts through positive selection, autologous transplantation may prove highly effective, especially when coupled with post-transplant immunotherapy. Some of these same methodologies have helped facilitate the use of autologous grafts for transplantation in patients with chronic myelogenous leukemia without allogeneic donors. Advances in the supportive care of transplant patients, including the pretransplant identification of those at risk from pulmonary complications and the use of cytokines to speed engraftment, have reduced morbidity and mortality to such a degree that it is appropriate to consider high-dose therapy and stem cell reconstitution in patients with nonmalignant diseases. The impressive advances that have occurred in transplantation for thalassemia are described by pioneers in their area of investigation. The burgeoning field of transplantation for autoimmune disorders, including its immunobiologic basis and soon-to- be-realized clinical potential, is also summarized. Continued progress in the use of high-dose therapy with stem cell rescue for the treatment of pediatric tumors, which derives in part from improved supportive care, is detailed. The sobering voice of the health care economists underscores the necessary limitations to our seemingly unbridled imagination. Cost- consciousness and financial know-how will need to be reflected in future study designs. Given the seemingly endless applications of our technology, strategies to insure its cost-effectiveness will be necessary. Continued financial support for laboratory investigation and for the clinical experiments they generate will be required if we are to go forward. Blood Stem Cell Transplantation lays the foundation for many of these future advances; it is incumbent upon us all to insure its realization.

Long Term Results Of Unrelated Hematopoietic Stem Cell Transplantation For Malignant Diseases In Brazil

Long Term Results Of Unrelated Hematopoietic Stem Cell Transplantation For Malignant Diseases In Brazil
Author: Bovo Priscila Fernanda
Publsiher: Unknown
Total Pages: 135
Release: 2017
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1250414811
Language: EN, FR, DE, ES & NL

Long Term Results Of Unrelated Hematopoietic Stem Cell Transplantation For Malignant Diseases In Brazil Book Review:

Long term results of Unrelated Hematopoietic Stem Cell Transplantation for malignant diseases in Brazil: 21 years of follow up.Bovo P1, Sola CB1, Nabhan S1, Setubal D1, Oliveira MM1, Bitencourt MA1, Pasquini R1, Funke VAM11Complexo Hospital de Clinicas -UFPRContext: During the last years, Hematopoietic Stem Cell Transplantation from unrelated donors (HSCT-UD) has increased. Better results have been achieved due to the development of less toxic conditioning regimens, new immunoprophylaxis strategies, and more accurate donor selection methods. Objectives: The primary endpoint was analyzing long-term results of adult patients who underwent HSCT-UD for malignant diseases. Secondary endpoints included risk factors analysis for overall survival (OS). Design: From September 1995 to November 2016, 179 patients older than 14 years have received HSCT-UD for malignant diseases at the BMT center of Federal University of Parana, Brazil. Information was collected from the Center database. Statistical analysis was performed using Graphpad Prism program. Kaplan-Meier method was used for survival curves; p level of significance

Advances in Allogeneic Hematopoietic Stem Cell Transplantation

Advances in Allogeneic Hematopoietic Stem Cell Transplantation
Author: Richard K. Burt,Mary M. Brush
Publsiher: Springer
Total Pages: 414
Release: 2012-11-28
ISBN 10: 1461549876
ISBN 13: 9781461549871
Language: EN, FR, DE, ES & NL

Advances in Allogeneic Hematopoietic Stem Cell Transplantation Book Review:

The field of hematopoietic stem cell transplantation is rapidly evolving. Realization that hematopoietic stem cells give rise to the immune compartment has resulted in clinical trials of hematopoietic stem cell transplantation for patients with autoimmune diseases. Allogeneic hematopoietic transplants are a form of adoptive immunotherapy resulting in beneficial graft versus tumor effects. Large numbers of hematopoietic cells can be collected with ease. Therefore, a renewable source of cells for ex vivo genetic manipulations is readily available. Multiple trials combining hematopoietic transplants and gene therapy are in progress. One such application is the infusion of allogeneic lymphocytes containing a suicide gene to abort graft versus host disease. Hematopoietic stem cell transplantation is in reality the clinical and practical application of cellular therapy. Hematopoietic transplant physicians are by design or by practical application evolving into cell and gene therapy specialists. The excitement and enthusiasm in hematopoietic transplantation is that it offers a door to the future. A future not of drugs or titrating poisonous chemotherapy but rather of cellular and gene therapy. 1 ALLOGENEIC PERIPHERAL BLOOD STEM CELL TRANSPLANTATION FOR HEMATOLOGIC DISEASES Martin Korbling University o/Texas MD. Anderson Cancer Center, Houston, Texas 77030 INTRODUCTION Circulating hematopoietic stem cells have emerged as an alternative to bone marrow (BM) stem cells for allografting. For many years the reconstitutive potential of circulating stem cells was questioned; peripheral blood stem cells (PBSC) were even characterized a waste product (1).

Allogeneic Stem Cell Transplantation

Allogeneic Stem Cell Transplantation
Author: Mary J. Laughlin,Hillard M. Lazarus
Publsiher: Springer Science & Business Media
Total Pages: 454
Release: 2003
ISBN 10: 1928374650XXX
ISBN 13: UOM:39015055860145
Language: EN, FR, DE, ES & NL

Allogeneic Stem Cell Transplantation Book Review:

Leading authorities provide a valuable account of the clinical and labratory issue related to allogeneic stem cell transplantation. Key chapters feature such topics as the selection of optimal inrelated allogeneic grafts for patients with hematologic malignancies; issues related to stem cell mobilization in normal donors; allogeneic peripheral blood cell vs marrow-derived transplantation; umbilical cord blood as a new stem cell source; kinetics of immune reconstitution post allogeneic transplantation; the role of allogeneic transplantation in breast cancer, and; the application of mini-conditioning in allogeneic grafting. The book will serve as a guide in development of innovative clinical and labratory inquiry in the field of allogeneic transplantation for all clinicians and labratory investigators focused on hematopoetic stem cells and immune biology research.

Thomas Hematopoietic Cell Transplantation 2 Volume Set

Thomas  Hematopoietic Cell Transplantation  2 Volume Set
Author: Stephen J. Forman,Robert S. Negrin,Joseph H. Antin,Frederick R. Appelbaum
Publsiher: John Wiley & Sons
Total Pages: 1416
Release: 2016-12-27
ISBN 10: 1118416007
ISBN 13: 9781118416006
Language: EN, FR, DE, ES & NL

Thomas Hematopoietic Cell Transplantation 2 Volume Set Book Review:

Fully revised for the fifth edition, this outstanding reference on bone marrow transplantation is an essential, field-leading resource. Extensive coverage of the field, from the scientific basis for stem-cell transplantation to the future direction of research Combines the knowledge and expertise of over 170 international specialists across 106 chapters Includes new chapters addressing basic science experiments in stem-cell biology, immunology, and tolerance Contains expanded content on the benefits and challenges of transplantation, and analysis of the impact of new therapies to help clinical decision-making Includes a fully searchable Wiley Digital Edition with downloadable figures, linked references, and more References for this new edition are online only, accessible via the Wiley Digital Edition code printed inside the front cover or at www.wiley.com/go/forman/hematopoietic.

Blood and Marrow Transplantation Long Term Management

Blood and Marrow Transplantation Long Term Management
Author: Bipin N. Savani
Publsiher: John Wiley & Sons
Total Pages: 416
Release: 2021-06-28
ISBN 10: 1119612691
ISBN 13: 9781119612698
Language: EN, FR, DE, ES & NL

Blood and Marrow Transplantation Long Term Management Book Review:

Hematopoietic cell transplantation (HCT) provides curative therapy for a variety of diseases. Over the past several decades, significant advances have been made in the field of HCT, to the point where HCT has become an integral part of treatment modality for a variety of hematologic malignancies and some nonmalignant diseases. HCT remains an important treatment option for a wide variety of hematologic and nonhematologic disorders, despite recent advances in the field of immunologic therapies. Factors driving this growth include expanded disease indications, greater donor options (expanding unrelated donor registries and haploidentical HCT), and accommodation of older and less fit recipients. The development of less toxic pretransplant conditioning regimens, more effective prophylaxis of graft-versus-host disease (GVHD), improved infection control, and other advances in transplant technology have resulted in a rapidly growing number of transplant recipients surviving long-term free of the disease for which they were transplanted. The changes over decades in the transplant recipient population and in the practice of HCT will have almost inevitably altered the composition of the long-term survivor population over time. Apart from an increasingly older transplant recipient cohort, the pattern of transplant indications has shifted from the 1990s when chronic myeloid leukemia made up a significant proportion of allo-HCT indications. Changes in cell source, donor types, conditioning regimens, GVHD prophylaxis, and supportive care have all occurred, with ongoing reductions in both relapse and non-relapse mortality (NRM) have been demonstrated. These patients have increased risks for a variety of late complications, which can cause morbidity and mortality. Most long-term survivors return to the care of their local hematologists/oncologists or primary care physicians, who may not be familiar with specialized monitoring and management of long complications after HCT for this patient population. As HCT survivorship increases, the focus of care has shifted to the identification and treatment of long-term complications that may affect quality of life and long-term morbidity and mortality. Preventive care as well as early detection and treatments are important aspects to reducing morbidity and mortality in long-term survivors after allo-HCT. This second edition, Blood and Marrow Transplantation Long-Term Management: Survivorship after Transplant, provides up-to-date information about diagnosis, screening, treatment, and long-term surveillance of long-term survivors after HCT.