Handbook of Pediatric Brain Imaging

Handbook of Pediatric Brain Imaging: Theory and Applications presents state of the art research on pediatric brain image acquisition and analysis from a broad range of imaging modalities that include MRI, EEG, MEG, PET, Ultrasound, NIRS, CT. With rapidly developing methods and applications of MRI, this book strongly emphasizes state of the art pediatric brain MRI, elaborating on the sub-categories of structure MRI, diffusion MRI, functional MRI, perfusion MRI and other MRI methods. The book integrates a pediatric brain imaging perspective into imaging acquisition and analysis methods, covering head motion, small brain sizes, small cerebral blood flow of neonates, dynamic cortical gyrification, white matter tract growth, differential maturation of functional networks, insufficient white matter myelination resulting in different image contrasts from adult brains. Presents state-of-the-art pediatric brain imaging methods and applications Shows how to optimize the pediatric neuroimaging acquisition and analysis protocols Shows how to obtain quantitative structural, functional and physiological measurements

Optical Coherence Tomography (OCT) plays a vital role in pediatric retina diagnosis, often revealing unrecognized retinal disorders and connections to brain injury, disease, and delayed neurodevelopment. Handbook of Pediatric Retinal OCT and the Eye-Brain Connection provides authoritative, up-to-date guidance in this promising area, showing how to optimize imaging in young children and infants, how to accurately interpret these images, and how to identify links between these images and brain and developmental disorders. Illustrates optimal methods of OCT imaging of children and infants, how to avoid pitfalls, and how to recognize and avoid artifacts Explains how the OCT image may relate to brain disease and delayed neurodevelopment Features more than 200 high-quality images and scans that depict the full range of disease in infants and young children Provides guidance in identifying retinal layers and important abnormalities. Covers the structural features of the retina and optic nerve head in developmental, acquired, or inherited conditions that affect the eye and visual pathways Offers practical ways to set up imaging programs in the clinic, operating room, or neonatal nursery

Neuroimaging, Part Two, a volume in The Handbook of Clinical Neurology series, illustrates how neuroimaging is rapidly expanding its reach and applications in clinical neurology. It is an ideal resource for anyone interested in the study of the nervous system, and is useful to both beginners in various related fields and to specialists who want to update or refresh their knowledge base on neuroimaging. This second volume covers imaging of the adult spine and peripheral nervous system, as well as pediatric neuroimaging. In addition, it provides an overview of the differential diagnosis of the most common imaging findings, such as ring enhancement on MRI, and a review of the indications for imaging in the most frequent neurological syndromes. The volume concludes with a review of neuroimaging in experimental animals and how it relates to neuropathology. It brings broad coverage of the topic using many color images to illustrate key points. Contributions from leading global experts are collated, providing the broadest view of neuroimaging as it currently stands. For a number of neurological disorders, imaging is not only critical for diagnosis, but also for monitoring the effect of therapies, with the entire field moving from curing diseases to preventing them. Most of the information contained in this volume reflects the newness of this approach, pointing to the new horizon in the study of neurological disorders. Provides a relevant description of the technologies used in neuroimaging, such as computed tomography, magnetic resonance imaging, positron emission tomography, and several others Discusses the application of these techniques to the study of brain and spinal cord disease Explores the indications for the use of these techniques in various syndromes

The most popular pediatric imaging text among radiology residents, program directors, and practitioners is now in its updated, expanded Third Edition. This edition's contributing authors include faculty of the Department of Radiology at Children's Hospital in Boston--the largest pediatric medical center in the United States. The state-of-the-art coverage highlights the expanding pediatric applications of ultrasound, CT, MRI, nuclear medicine, and vascular/interventional techniques. A new chapter on head and neck imaging is also included. Complementing the text are more than 2,000 scans and line drawings--over 1,300 new to this edition--as well as numerous diagnostic algorithms and tables of differential diagnosis.

Written by prominent researchers and consultants in the field of pediatric psychology and psychiatry, this first volume covers: developmental issues and disabilities, legal issues in a pediatric setting, sleep, anxiety, and eating disorders, substance abuse, and much more.

ìBy far, the most comprehensive and detailed coverage of pediatric neuropsychology available in a single book today, Davis provides coverage of basic principles of pediatric neuropsychology, but overall the work highlights applications to daily practice and special problems encountered by the pediatric neuropsychologist.î Cecil R. Reynolds, PhD Texas A&M University "The breadth and depth of this body of work is impressive. Chapters written by some of the best researchers and authors in the field of pediatric neuropsychology address every possible perspective on brain-behavior relationships culminating in an encyclopedic textÖ. This [book] reflects how far and wide pediatric neuropsychology has come in the past 20 years and the promise of how far it will go in the next." Elaine Fletcher-Janzen, EdD, NCSP, ABPdN The Chicago School of Professional Psychology "...it would be hard to imagine a clinical situation in pediatric neuropsychology in whichthis book would fail as a valuable resource."--Archives of Clinical Neuropsychology "I believe there is much to recommend this hefty volume. It is a solid reference that I can see appreciating as a resource as I update my training bibliography."--Journal of the International Neuropsychological Society This landmark reference covers all aspects of pediatric neuropsychology from a research-based perspective, while presenting an applied focus with practical suggestions and guidelines for clinical practice. Useful both as a training manual for graduate students and as a comprehensive reference for experienced practitioners, it is an essential resource for those dealing with a pediatric population. This handbook provides an extensive overview of the most common medical conditions that neuropsychologists encounter while dealing with pediatric populations. It also discusses school-based issues such as special education law, consulting with school staff, and reintegrating children back into mainstream schools. It contains over 100 well-respected authors who are leading researchers in their respective fields. Additionally, each of the 95 chapters includes an up-to-date review of available research, resulting in the most comprehensive text on pediatric neuropsychology available in a single volume. Key Features: Provides thorough information on understanding functional neuroanatomy and development, and on using functional neuroimaging Highlights clinical practice issues, such as legal and ethical decision-making, dealing with child abuse and neglect, and working with school staff Describes a variety of professional issues that neuropsychologists must confront during their daily practice, such as ethics, multiculturalism, child abuse, forensics, and psychopharmacology

"This book provides insights on how deep learning, together with IOT, will impact various sectors such as healthcare, agriculture, cyber security, and social media analysis applications offering solutions to various real-world problems using these methods from various researchers' point of views"--

Considerable research has been devoted to understanding how positive emotional processes influence our thoughts and behaviors, and the resulting body of work clearly indicates that positive emotion is a vital ingredient in our human quest towards well-being and thriving. Yet the role of positive emotion in psychopathology has been underemphasized, such that comparatively less scientific attention has been devoted to understanding ways in which positive emotions might influence and be influenced by psychological disturbance. Presenting cutting-edge scientific work from an internationally-renowned group of contributors, The Oxford Handbook of Positive Emotion and Psychopathology provides unparalleled insight into the role of positive emotions in mental health and illness. The book begins with a comprehensive overview of key psychological processes that link positive emotional experience and psychopathological outcomes. The following section focuses on specific psychological disorders, including depression, anxiety, trauma, bipolar disorder, and schizophrenia, as well as developmental considerations. The third and final section of the Handbook discusses translational implications of this research and how examining populations characterized by positive emotion disturbance enables a better understanding of psychiatric course and risk factors, while simultaneously generating opportunities to bridge gaps between basic science models and psychosocial interventions. With its rich and multi-layered focus, The Oxford Handbook of Positive Emotion and Psychopathology will be of interest to researchers, teachers, and students from a range of disciplines, including social psychology, clinical psychology and psychiatry, biological psychology and health psychology, affective science, and neuroscience.

This volume of the Handbook introduces the basic science of child and adolescent psychiatry and presents a myriad of treatment options available to psychiatrists. These include clinical treatments, such as diet and drug therapy, hypnotherapy and biofeedback; residential or day treatment options; group and family therapy; aggressive interventions such as therapeutic foster placement or adoption; creative treatments, such as art and music therapy; and rehabilitative therapy, including vocational therapy, educational therapy and therapeutic camping.

Part of the practical and popular Handbooks in Radiology series, HANDBOOK OF PEDIATRIC RADIOLOGY covers the basic facts and key concepts of the subspecialty in a unique outline format. The result is a concise and comprehensive review of the basics of pediatric image interpretation in an organized, easy-to-use guide -- an excellent quick reference for the practitioner, and ideal for use in preparing for exams in pediatric radiology. Its compact, portable size makes it a truly practical reference for day-to-day use. * Provides thorough, multi-modality coverage of "the basics" for interpreting diagnostic imaging studies of infants and children. * Features an easy-to-read outline format, making it a unique tool for Board and CAQ review, as well as an excellent quick reference for the practicing radiologist. * Includes "Key Concepts" boxes at the beginning of each chapter for an at-a-glance review of the most common features of each disease/disorder covered. * Presents "Imaging" boxes throughout, with detailed information on the specifics of how to perform and evaluate various imaging studies. * Organizes information logically by organ system, then by disease/disorder category, so necessary data can be found quickly by the reader. * Features more than 176 state-of-the-art, detailed line drawings that provide a clear image of concepts under discussion. * Contains treatment options.

Treatment of patients with a brain tumor remains one of the most challenging and difficult areas of modern oncology. Recent advances in the molecular biology of these neoplasms have improved our understanding of the malignant phenotype and have lead to the development of novel forms of chemotherapy, including “targeted agents. The Handbook of Brain Tumor Chemotherapy reviews the state-of-the-art of chemotherapy development and clinical treatment of patients with this devastating disease. Handbook of Brain Tumor Chemotherapy offers a unique cutting-edge compendium of basic science and clinical information on the subject of brain tumor chemotherapy, reviewing what has been accomplished thus far and how the field will continue to evolve with the development of more specific and efficacious chemotherapeutic agents. This book represents the most complete single-volume resource available for information on the subject of brain tumor chemotherapy. Provides the most up to date information regarding conventional forms of cytotoxic chemotherapy, as well as the basic science and clinical application of molecular therapeutics, for the treatment of brain tumors Broadly appeals to anyone interested in the field of Neuro-Oncology and in the treatment of patients with brain tumors Useful to clinicians interested in a thorough overview of the use of chemotherapy in patients with a broad range of brain tumors as well as serving as a source of background information to basic scientists and pharmaceutical researchers with an interest in the molecular therapeutics of brain tumors

Based on Dr. Wright’s classic major reference, Handbook of Pediatric Strabismus and Amblyopia outlines the latest findings in diagnosing the most commonly presenting problems in pediatic cases, offering the most complete assessment tools for accurate diagnosis and then best treatment options. Distilling the essentials of these prevelant and sometimes complicated cases into a portable, complete and authorative pocket reference, this handbook offers a complete picture of how to best treat pediatric patients. Specifically, the introductory chapters on the specifics of pediatric ophthalmology (embryology, post-natal development and the pediatric exam) will help newcomers to pediatric practice fully grasp the subtle differences in pediatric care. The chapters are written by leading experts in the field and are presented in a user-friendly format, relying on heavily illustrated in color plates, clincally helpful tables, charts, and decision-making guidelines. This approach will enable the practitioner (whether specialist or generalist) to make the most accurate diagnosis and choose the most effective treatment option.

The Pediatric Procedural Sedation Handbook provides a comprehensive but concise review of the essential information needed to allow for the safe practice of pediatric procedural sedation. Written by a group of multidisciplinary authors, this text explores the fundamentals of sedation, procedural sedation, special patient considerations, diagnostic and therapeutic procedures, and more. Each chapter offers a starting point and suggestions for further in-depth study of all aspects of providing safe, effective, multidisciplinary-team based sedation care for children undergoing testing and procedures outside of an operating room setting. Appendices providing medication dosing and delivery route suggestions complement the text and can be used for quick reference. This book is a must-read for any clinician involved in modern, team-based patient-centered care, including physicians, nurses, dentists, and child life specialists. Editors and authors are members of the Society of Pediatric Sedation, a multidisciplinary society dedicated to the advance of pediatric sedation by promoting safe, high quality care, innovative research, and quality professional education.

“The editors...have done an outstanding job of presenting...complex information in a lucid manner – this book is a must-read for the global community of aspiring students and neuro-oncology practitioners.” Amar Gajjar, MD in the Foreword This is a succinct introduction to pediatric neuro-oncology. It summarizes the key advances in molecular biology that have helped transform this rapidly evolving field and provides up-to-date coverage of major and emerging treatment modalities as well as supportive care. Separate chapters present each kind of pediatric brain cancer and its diagnosis and treatment. As more children survive brain cancer, the importance of quality of life issues and helping survivors to cope with the neuropsychological impact and long-term effects of current therapies has come into sharper focus; these topics are also addressed in the book, as are palliative care and pediatric neuro-oncology in countries with limited resources. The book is aimed at trainees and practitioners who seek an up-to-date text in pediatric neuro-oncology that is both comprehensive and concise.

Your accessible guide to the essentials of pediatric diagnostic imaging! Pediatric Radiology: Practical Imaging Evaluation of Infants and Children provides vital insights on how to diagnose both common and rare, congenital and acquired disorders in infants and children using the best imaging approaches available today. And, it does so in a highly concise, practical manner that makes this information easy to understand and apply. Contributions from a host of respected international authorities put the most relevant, expert information from around the world at your fingertips.

This volume contains an overview of the history of the field of child psychiatry and examines contemporary issues facing child and adolescent psychiatrists, including the roles that changing family dynamics, multi-culturalism, new technologies, play in children's development, specialized applications such as forensic psychiatry; and insurance-related, ethical and administrative issues that affect child psychiatrists' practices.

This four-volume text features contributions from over 300 researchers and clinicians. Volumes 1, 2 and 3 explore the developmental stages and syndromes of infancy and preschool, grade school and adolescence. Each volume addresses the normal development during each period, the theoretical and clinical perspectives and the clinical syndromes most commonly associated with it. Volume 4 explores the varieties of development and the impact of psychosocial, medical, and foreign cultural factors on development of all three age groups.

Holbourne’s theory that rotational head movement and shear strains were limiting factors in producing acute parenchymal brain damage was a watershed moment in understanding traumatic brain injury (TBI). Long term effects, and in particular neurodegenerative proteinopathy subsequent to TBI, remain theoretical, notwithstanding the poorly understood ‘punch drunk’ syndrome of the early and mid-20th century, and the 21st century concept of chronic traumatic encephalopathy. This book, the Handbook of Traumatic Brain Injury and Neurodegeneration, has as its theme the marriage between neurodegenerative disease and neurotrauma through TBI surrogates such as sport, military service, and experimental models, and the legitimacy of that marriage. In the 32 contributions included here, this handbook not only explores the deleterious effects of genuine TBI, but also, and more importantly, the relationship between TBI and neurodegeneration. Controversy notwithstanding, there is much to be learned about the biological effects of TBI, substrates for long-term sequelae, the relationship between TBI and diverse neuropsychiatric disorders, and targets for therapy. The overall message to the neuroscience community from these papers may be a cautionary tale. The null hypothesis, that there is no causal relationship between TBI and progressive neurodegenerative disease, appears to be very much in play, and the book will be of interest to all those working in the field.

This pocket-sized, practical guide to the investigations available for all pediatric disorders, with an emphasis on the routine tests that can be carried out based on the presenting symptoms. Organised by major body systems, the book provides answers to all the questions that arise when investigating a child, such as: 'How selective can I be with the application of tests?' 'How do I do the test?' 'What do the results mean?' By providing practical and concise information the Handbook of Pediatric Investigations will be an invaluable resource for all those involved in the decisions on the care of children. Covers all major body systems in one volume Develops systematic approach to clinical testing Discusses interpretation of test results to reach a diagnosis Written by proven teachers in the field of paediatrics Concise and consistent format

The Oxford Handbook of Functional Brain Imaging in Neuropsychology and Cognitive Neurosciences describes in a readily accessible manner the several functional neuroimaging methods and critically appraises their applications that today account for a large part of the contemporary cognitive neuroscience and neuropsychology literature. The complexity and the novelty of these methods often cloud appreciation of the methods' contributions and future promise. The Handbook begins with an overview of the basic concepts of functional brain imaging common to all methods, and proceeds with a description of each of them, namely magnetoencephalography (MEG), functional magnetic resonance imaging (fMRI), positron emission tomography (PET), diffusion tensor imaging (DTI), and transcranial magnetic stimulation (TMS). Its second part covers the various research applications of functional neuroimaging on issues like the function of the default mode network; the possibility and the utility of imaging of consciousness; the search for mnemonic traces of concepts; human will and decision-making; motor cognition; language; the mechanisms of affective states and pain; the presurgical mapping of the brain; and others. As such, the volume reviews the methods and their contributions to current research and comments on the degree to which they have enhanced our understanding of the relation between neurophysiological activity and sensory, motor, and cognitive functions. Moreover, it carefully considers realistic contributions of functional neuroimaging to future endeavors in cognitive neuroscience, medicine, and neuropsychology.