Handbook of Clinical Adult Genetics and Genomics

Handbook of Clinical Adult Genetics and Genomics
Author: Shweta Dhar,Sandesh Sreenath Chakravarthy Nagamani,Tanya Eble
Publsiher: Academic Press
Total Pages: 534
Release: 2020-04-10
ISBN 10: 0128173459
ISBN 13: 9780128173459
Language: EN, FR, DE, ES & NL

Handbook of Clinical Adult Genetics and Genomics Book Review:

Handbook of Clinical Adult Genetics and Genomics: A Practice-Based Approach provides a thorough overview of genetic disorders that are commonly encountered in adult populations and supports the full translation of adult genetic and genomic modalities into clinical practice. Expert chapter authors supplement foundational knowledge with case-based strategies for the evaluation and management of genetic disorders in each organ system and specialty area. Topics discussed include employing genetic testing technologies, reporting test results, genetic counseling for adult patients, medical genetics referrals, issues of complex inheritance, gene therapy, and diagnostic and treatment criteria for developmental, cardiovascular, gastrointestinal, neuropsychiatric, pulmonary issues, and much more. Employs clinical case studies to demonstrate how to evaluate, diagnosis and treat adult patients with genetic disorders Offers a practical framework for establishing an adult genetics clinic, addressing infrastructure, billing, counseling, and challenges unique to adult clinical genetics Features chapter contributions from authors at leading adult genetics institutions in the US and abroad

Oxford Desk Reference

Oxford Desk Reference
Author: Helen V. Firth,Jane A. Hurst,Judith G. Hall
Publsiher: Oxford University Press, USA
Total Pages: 708
Release: 2005
ISBN 10: 9780192628961
ISBN 13: 0192628968
Language: EN, FR, DE, ES & NL

Oxford Desk Reference Book Review:

Judith G. Hall is a 2011 Fellow of The Royal Society of Canada. The first in a brand new series of easy-to-use guides, this book is set to become the bible for clinical consultation in genetics. It covers the process of diagnosis, investigation, management, and counselling for patients. Most of the topics fit onto a double-page spread ensuring that the book is an accessible, quick reference for the clinic or hospital consultation. Where available, diagnostic criteria for specific conditions are included as well as contact details for support groups. The book is well illustrated and has an up-to-date bibliography and glossaries of terms used in genetics and dysmorphology. The authors have used their experience to devise a practical clinical approach to many common genetic referrals, both out patient and ward based. The most common Mendelian disorders, chromosomal disorders, congenital anomalies and syndromes are all covered. In addition there are chapters on familial cancer and pregnancy-related topics such as foetal anomalies, teratogens, prenatal and pre-implantation diagnosis. The book also provides information on the less common situations, where management is particularly complex, or important genetic concepts are illustrated.

Oxford Handbook of Genetics

Oxford Handbook of Genetics
Author: Guy Bradley-Smith,Sally Hope,Helen V. Firth,Jane A. Hurst
Publsiher: Oxford University Press
Total Pages: 449
Release: 2009-10-29
ISBN 10: 0199545367
ISBN 13: 9780199545360
Language: EN, FR, DE, ES & NL

Oxford Handbook of Genetics Book Review:

Genetics is a rapidly changing field, making it difficult for Primary Care practitioners to keep up to date. This book is a collaboration between 2 consultant geneticists, and 2 experienced GPs. This small book provides accessible information, including explanatory diagrams and family trees, about both specific genetic diseases and the possible genetic components of major diseases, such as heart disease and diabetes, for the primary health care team. It aims tohelp practitioners to know why, when and where they should refer patients or affected families to get the best advice about, or surveillance of, genetic disease. It also contains information about the genetic testing which may be offered in secondary care. Each chapter also contains a list ofresources which might be of further use to the practitioner or their patient. There are chapters on cancer, as well as antenatal screening, and specific problems that may arise from such screening.

Genomic Medicine

Genomic Medicine
Author: Dhavendra Kumar,Charis Eng
Publsiher: Oxford University Press (UK)
Total Pages: 814
Release: 2014
ISBN 10: 019989602X
ISBN 13: 9780199896028
Language: EN, FR, DE, ES & NL

Genomic Medicine Book Review:

Preceded by Genomics and clinical medicine / edited by Dhavendra Kumar. [First edition]. 2008.

Medical and Health Genomics

Medical and Health Genomics
Author: Dhavendra Kumar,Stylianos Antonarakis
Publsiher: Academic Press
Total Pages: 358
Release: 2016-06-04
ISBN 10: 0127999221
ISBN 13: 9780127999227
Language: EN, FR, DE, ES & NL

Medical and Health Genomics Book Review:

Medical and Health Genomics provides concise and evidence-based technical and practical information on the applied and translational aspects of genome sciences and the technologies related to non-clinical medicine and public health. Coverage is based on evolving paradigms of genomic medicine—in particular, the relation to public and population health genomics now being rapidly incorporated in health management and administration, with further implications for clinical population and disease management. Provides extensive coverage of the emergent field of health genomics and its huge relevance to healthcare management Presents user-friendly language accompanied by explanatory diagrams, figures, and many references for further study Covers the applied, but non-clinical, sciences across disease discovery, genetic analysis, genetic screening, and prevention and management Details the impact of clinical genomics across a diverse array of public and community health issues, and within a variety of global healthcare systems

Principles of Clinical Cancer Genetics

Principles of Clinical Cancer Genetics
Author: Daniel C. Chung,Daniel A. Haber
Publsiher: Springer Science & Business Media
Total Pages: 227
Release: 2010-07-20
ISBN 10: 9780387938462
ISBN 13: 038793846X
Language: EN, FR, DE, ES & NL

Principles of Clinical Cancer Genetics Book Review:

Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Genetic Diagnosis of Endocrine Disorders

Genetic Diagnosis of Endocrine Disorders
Author: Roy E. Weiss,Samuel Refetoff
Publsiher: Academic Press
Total Pages: 472
Release: 2015-10-09
ISBN 10: 0128011343
ISBN 13: 9780128011348
Language: EN, FR, DE, ES & NL

Genetic Diagnosis of Endocrine Disorders Book Review:

Genetic Diagnosis of Endocrine Disorders, Second Edition provides users with a comprehensive reference that is organized by endocrine grouping (i.e., thyroid, pancreas, parathyroid, pituitary, adrenal, and reproductive and bone), discussing the genetic and molecular basis for the diagnosis of various disorders. The book emphasizes the practical nature of diagnosing a disease, including which tests should be done for the diagnosis of diabetes mellitus in adults and children, which genes should be evaluated for subjects with congenital hypothyroidism, which genetic tests should be ordered in obese patients or for those with parathyroid carcinoma, and the rationale behind testing for multiple endocrine neoplasias. Offers a clear presentations of pharmacogenetics and the actual assays used in detecting endocrine diseases Teaches the essentials of the genetic basis of disease in each major endocrine organ system Offers expert advice from genetic counselors on how to use genetic information in counseling patients Includes new chapters on the genetics of lipid disorders and glycogen storage diseases, genetics of hypoglycemia, and whole genome/exome sequencing

Handbook of Pharmacogenomics and Stratified Medicine

Handbook of Pharmacogenomics and Stratified Medicine
Author: Sandosh Padmanabhan
Publsiher: Academic Press
Total Pages: 1118
Release: 2014-04-28
ISBN 10: 0123868831
ISBN 13: 9780123868831
Language: EN, FR, DE, ES & NL

Handbook of Pharmacogenomics and Stratified Medicine Book Review:

Handbook of Pharmacogenomics and Stratified Medicine is a comprehensive resource to understand this rapidly advancing field aiming to deliver the right drug at the right dose to the right patient at the right time. It is designed to provide a detailed, but accessible review of the entire field from basic principles to applications in various diseases. The chapters are written by international experts to allow readers from a wide variety of backgrounds, clinical and non-clinical (basic geneticists, pharmacologists, clinicians, trialists, industry personnel, ethicists) to understand the principles underpinning the progress in this area, the successes, failures and the challenges ahead. To be accessible to the widest range of readers, the clinical application section introduces the disease process, existing therapies, followed by pharmacogenomics and stratified medicine details. Medicine is the cornerstone of modern therapeutics prescribed on the basis that its benefit should outweigh its risk. It is well known that people respond differently to medications and in many cases the risk-benefit ratio for a particular drug may be a gray area. The last decade has seen a revolution in genomics both in terms of technological innovation and discovering genetic markers associated with disease. In parallel there has been steady progress in trying to make medicines safer and tailored to the individual. This has occurred across the whole spectrum of medicine, some more than others. In addition there is burgeoning interest from the pharmaceutical industry to leverage pharmacogenomics for more effective and efficient clinical drug development. Provides clinical and non-clinical researchers with practical information normally beyond their usual areas of research or expertise Includes an basic principles section explaining concepts of basic genetics, genetic epidemiology, bioinformatics, pharmacokinetics and pharmacodynamics Covers newer technologies– next generation sequencing, proteomics, metabolomics Provides information on animal models, lymphoblastoid cell lines, stem cells Provides detailed chapters on a wide range of disease conditions, implementation and regulatory issues Includes chapters on the global implications of pharmacogenomics

Ethical Dilemmas in Genetics and Genetic Counseling

Ethical Dilemmas in Genetics and Genetic Counseling
Author: Janice L. Berliner
Publsiher: Oxford University Press, USA
Total Pages: 226
Release: 2014-09-25
ISBN 10: 019994489X
ISBN 13: 9780199944897
Language: EN, FR, DE, ES & NL

Ethical Dilemmas in Genetics and Genetic Counseling Book Review:

By using a creative approach that focuses on a single extended family as a case example to illustrate each chapter's key point, the authors elucidate ethical issues arising in the genetics clinic and laboratory surrounding many timely issues.

The Oxford Handbook of Adult Cognitive Disorders

The Oxford Handbook of Adult Cognitive Disorders
Author: Michael L. Alosco,Robert A. Stern
Publsiher: Oxford Library of Psychology
Total Pages: 944
Release: 2019-06-03
ISBN 10: 0190664126
ISBN 13: 9780190664121
Language: EN, FR, DE, ES & NL

The Oxford Handbook of Adult Cognitive Disorders Book Review:

The prevalence of adult cognitive disorders will dramatically rise over the next 25 years due to the aging population. Clinical research on adult cognitive disorders has rapidly evolved, including evidence of new adult cognitive disorders and greater insight into the clinical presentation, mechanism, diagnosis, and treatment of established diseases. The Oxford Handbook of Adult Cognitive Disorders is an up-to-date, scholarly, and comprehensive volume covering most diseases, conditions, and injuries resulting in impairments in cognitive function in adults. Topics covered include normal cognitive and brain aging, the impact of medical disorders and psychiatric illnesses on cognitive function, adult neurodevelopmental disorders, and various neurological conditions. This Handbook also provides a section on unique perspectives and special considerations for clinicians and clinical researchers, covering topics such as cognitive reserve, genetics, diversity, and neuroethics. Readers will be able to draw upon this volume to facilitate clinical practice (including differential diagnosis, treatment recommendations, assessment practices), and to obtain an in-depth review of current research across a wide spectrum of disorders, provided by leaders in their fields. The Oxford Handbook of Adult Cognitive Disorders is a one-of a kind resource appropriate for both clinicians and clinical researchers, from advanced trainees to seasoned professionals.

Human Malformations and Related Anomalies

Human Malformations and Related Anomalies
Author: Roger E. Stevenson,Judith G. Hall
Publsiher: Oxford University Press
Total Pages: 1520
Release: 2005-10-27
ISBN 10: 019974808X
ISBN 13: 9780199748082
Language: EN, FR, DE, ES & NL

Human Malformations and Related Anomalies Book Review:

This widely acclaimed reference work gives a comprehensive survey of all significant human malformations and related anomalies from the perspective of the clinician. The anomalies are organized by anatomical system and presented in a consistent manner, including details of the clinical presentation, epidemiology, embryology, treatment and prevention for each anomaly. When known, the molecular or other pathogenetic basis for the malformation is given. Most anomalies are illustrated by photographs or drawings. Specific malformations are linked to syndromes through the extensive use of differential diagnosis tables. Over a decade has passed since the first edition of this book was published, and the revised edition fully incorporates the advances made in the field during the intervening years.. It reflects new understanding of human developmental biology that has emerged from molecular, cytogenetic, and biochemical studies; new observations by clinicians as well as enhanced diagnostic and prevention capacities; and more accurate and comprehensive epidemiology. By condensing much of the information presented in the first volume of the previous edition, and exercising rigorous editorial control, Drs. Stevenson and Hall and their contributors have managed to update the book while reducing its size to that of a single volume. All clinicians and scientists interested in birth defects, including pediatricians, geneticists, genetic counselors, obstetricians, and pediatric pathologists, will find this book to be an invaluable source of information.

Molecular Medicine for Clinicians

Molecular Medicine for Clinicians
Author: Barry Mendelow,Nanthakumarn Chetty
Publsiher: Wits University Press
Total Pages: 528
Release: 2008-01-01
ISBN 10: 1868144658
ISBN 13: 9781868144655
Language: EN, FR, DE, ES & NL

Molecular Medicine for Clinicians Book Review:

An introductory text for medical registrars about molecular medicine in South Africa The insights following the wake of the Human Genome project are radically influencing our understanding of the molecular basis of life, health and disease. The improved accuracy and precision of clinical diagnostics is also beginning to have an impact on therapeutics in a fundamental way. This book is suitable for undergraduate medical students, as part of their basic sciences training, but is also relevant to interested under- and postgraduate science and engineering students. It serves as an introductory text for medical registrars in virtually all specialties, and is also of value to the General Practitioner wishing to keep up to date, especially in view of the growing, internet-assisted public knowledge of the field. There is a special focus on the application of molecular medicine in Africa and in developing countries elsewhere.

Stress Genetics Epigenetics and Genomics

Stress  Genetics  Epigenetics and Genomics
Author: George Fink
Publsiher: Academic Press
Total Pages: 344
Release: 2020-10-24
ISBN 10: 0128131578
ISBN 13: 9780128131572
Language: EN, FR, DE, ES & NL

Stress Genetics Epigenetics and Genomics Book Review:

This fourth volume in the Handbook of Stress series, Stress: Genetics, Epigenetics and Genomics, deals with the influence that genetics, epigenetics, and genomics have on the effects of and responses to stress. Chapters refer to epigenetic mechanisms that involve DNA methylation, histone modification, and/or noncoding RNA-associated gene activation or silencing. There is also coverage of epigenetic mechanisms in stress-related transgenerational transmission of characteristics, and how these may help explain heritability in some complex human diseases. The Handbook of Stress series, comprised of self-contained volumes that each focus on a specific stress area, covers the significant advances made since the publication of Elsevier’s Encyclopedia of Stress (2000 and 2007). Volume 4 is ideal for graduate students, post-doctoral fellows, faculty and clinicians interested in stress genetics, epigenetics and genomics involved in neuroendocrinology, neuroscience, biomedicine, endocrinology, psychology, psychiatry and the social sciences. Articles carefully selected by eminent stress researchers and prepared by contributors representing outstanding scholarship in the field, with each chapter fully vetted for reliable expert knowledge Richly illustrated with explanatory figures and tables Each chapter includes a boxed “Key points call out section Affordably priced, self-contained volume for readers specifically interested in stress genetics and epigenetics, removing the need to purchase the whole Handbook series

The Oxford Handbook of Public Health Ethics

The Oxford Handbook of Public Health Ethics
Author: Anna C. Mastroianni,Jeffrey P. Kahn,Nancy E. Kass
Publsiher: Oxford University Press, USA
Total Pages: 944
Release: 2019-08-19
ISBN 10: 0190245190
ISBN 13: 9780190245191
Language: EN, FR, DE, ES & NL

The Oxford Handbook of Public Health Ethics Book Review:

Natural disasters and cholera outbreaks. Ebola, SARS, and concerns over pandemic flu. HIV and AIDS. E. coli outbreaks from contaminated produce and fast foods. Threats of bioterrorism. Contamination of compounded drugs. Vaccination refusals and outbreaks of preventable diseases. These are just some of the headlines from the last 30-plus years highlighting the essential roles and responsibilities of public health, all of which come with ethical issues and the responsibilities they create. Public health has achieved extraordinary successes. And yet these successes also bring with them ethical tension. Not all public health successes are equally distributed in the population; extraordinary health disparities between rich and poor still exist. The most successful public health programs sometimes rely on policies that, while improving public health conditions, also limit individual rights. Public health practitioners and policymakers face these and other questions of ethics routinely in their work, and they must navigate their sometimes competing responsibilities to the health of the public with other important societal values such as privacy, autonomy, and prevailing cultural norms. This Oxford Handbook provides a sweeping and comprehensive review of the current state of public health ethics, addressing these and numerous other questions. Taking account of the wide range of topics under the umbrella of public health and the ethical issues raised by them, this volume is organized into fifteen sections. It begins with two sections that discuss the conceptual foundations, ethical tensions, and ethical frameworks of and for public health and how public health does its work. The thirteen sections that follow examine the application of public health ethics considerations and approaches across a broad range of public health topics. While chapters are organized into topical sections, each chapter is designed to serve as a standalone contribution. The book includes 73 chapters covering many topics from varying perspectives, a recognition of the diversity of the issues that define public health ethics in the U.S. and globally. This Handbook is an authoritative and indispensable guide to the state of public health ethics today.

Muscle

Muscle
Author: Joseph Hill
Publsiher: Academic Press
Total Pages: 1398
Release: 2012
ISBN 10: 012381510X
ISBN 13: 9780123815101
Language: EN, FR, DE, ES & NL

Muscle Book Review:

The Parathyroids

The Parathyroids
Author: John P. Bilezikian,Robert Marcus,Michael A. Levine
Publsiher: Elsevier
Total Pages: 881
Release: 2001-07-21
ISBN 10: 9780080525778
ISBN 13: 0080525776
Language: EN, FR, DE, ES & NL

The Parathyroids Book Review:

Written by world experts, this books follows upon the monumental success of the first edition of The Parathyroids, which was universally acclaimed as the best text on the subject. An authoritative reference that spans the basic science of parathyroid hormone treatment to major clinical disorders in a superb, single compendium, The Parathyroids offers an objective and authoritative view on controversial clinical issues in this rapidly changing field. Every medical school library and virtually every major hospital library will need this book as a reference for students and clinicians. Key Features * Offers objective and authoritative reviews on controversial clinical issues * Written by world experts on parathyroid hormone and its disorders * Superb, state-of-the-art compendium in one convenient volume * Bridges basic science of parathyroid hormone to major clinical disorders * Practical information on clinical management of parathyroid hormone disorders

Genetics

Genetics
Author: Daniel L. Hartl,Maryellen Ruvolo
Publsiher: Jones & Bartlett Publishers
Total Pages: 800
Release: 2011-08-05
ISBN 10: 1449626106
ISBN 13: 9781449626105
Language: EN, FR, DE, ES & NL

Genetics Book Review:

The Eighth Edition of Genetics: Analysis of Genes and Genomes provides a clear, balanced, and comprehensive introduction to genetics and genomics at the college level. Expanding upon the key elements that have made this text a success, Hartl has included updates throughout, as well as a new chapter dedicated to genetic evolution. He continues to treat transmission genetics, molecular genetics, and evolutionary genetics as fully integrated subjects and provide students with an unprecedented understanding of the basic process of gene transmission, mutation, expression, and regulation. New chapter openers include a new section highlighting scientific competencies, while end-of-chapter Guide to Problem-Solving sections demonstrate the concepts needed to efficiently solve problems and understand the reasoning behind the correct answer. Important Notice: The digital edition of this book is missing some of the images or content found in the physical edition.

Cardiovascular Genetics and Genomics

Cardiovascular Genetics and Genomics
Author: Dan M. Roden
Publsiher: John Wiley & Sons
Total Pages: 288
Release: 2009-04-01
ISBN 10: 9781444311778
ISBN 13: 1444311778
Language: EN, FR, DE, ES & NL

Cardiovascular Genetics and Genomics Book Review:

This comprehensive and concise presentation of genetic factors in cardiovascular disease and their response to therapy consolidates knowledge of this high-interest and emerging topic. Covering broad areas of contemporary genomic medicine and specific cardiovascular diseases, this book is a must for anyone seeking to better understand this rapidly developing field.

Oxford Textbook of Cancer Biology

Oxford Textbook of Cancer Biology
Author: Francesco Pezzella,Mahvash Tavassoli,David Kerr
Publsiher: Oxford University Press
Total Pages: 496
Release: 2019-05-02
ISBN 10: 0198779453
ISBN 13: 9780198779452
Language: EN, FR, DE, ES & NL

Oxford Textbook of Cancer Biology Book Review:

The study of the biology of tumours has grown to become markedly interdisciplinary, involving chemists, statisticians, epidemiologists, mathematicians, bioinformaticians, and computer scientists alongside biologists, geneticists, and clinicians. The Oxford Textbook of Cancer Biology brings together the most up-to-date developments from different branches of research into one coherent volume, providing a comprehensive and current account of this rapidly evolving field. Structured in eight sections, the book starts with a review of the development and biology of multi-cellular organisms, how they maintain a healthy homeostasis in an individual, and a description of the molecular basis of cancer development. The book then illustrates, as once cells become neoplastic, their signalling network is altered and pathological behaviour follows. It explores the changes that cancer cells can induce in nearby normal tissue, the new relationship established between them and the stroma, and the interaction between the immune system and tumour growth. The authors illustrate the contribution provided by high throughput techniques to map cancer at different levels, from genomic sequencing to cellular metabolic functions, and how information technology, with its vast amounts of data, is integrated with traditional cell biology to provide a global view of the disease. The effect of the different types of treatments on the biology of the neoplastic cells are explored to understand on the one side, why some treatments succeed, and on the other, how they can affect the biology of resistant and recurrent disease. The book concludes by summarizing what we know to date about cancer, and in what direction our understanding of cancer is moving. Edited by leading authorities in the field with an international team of contributors, this book is an essential resource for scholars and professionals working in the wide variety of sub-disciplines that make up today's cancer research and treatment community. It is written not only for consultation, but also for easy cover-to-cover reading.

The Laboratory Mouse

The Laboratory Mouse
Author: Hans Hedrich
Publsiher: Academic Press
Total Pages: 868
Release: 2012-06-14
ISBN 10: 012382009X
ISBN 13: 9780123820099
Language: EN, FR, DE, ES & NL

The Laboratory Mouse Book Review:

The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries