Hair Analysis in Clinical and Forensic Toxicology

Hair Analysis in Clinical and Forensic Toxicology
Author: Pascal Kintz,Alberto Salomone,Marco Vincenti
Publsiher: Academic Press
Total Pages: 392
Release: 2015-06-25
ISBN 10: 0128017104
ISBN 13: 9780128017104
Language: EN, FR, DE, ES & NL

Hair Analysis in Clinical and Forensic Toxicology Book Review:

Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair Demonstrates toxicological techniques relating to a variety of scenarios and exposure types Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results

Drug Testing in Hair

Drug Testing in Hair
Author: Pascal Kintz
Publsiher: CRC Press
Total Pages: 304
Release: 2020-08-18
ISBN 10: 1000099245
ISBN 13: 9781000099249
Language: EN, FR, DE, ES & NL

Drug Testing in Hair Book Review:

Drug Testing in Hair is the first book on this timely and controversial topic. The book's purpose is to validate hair testing as an accepted form of evidence for use in courts and elsewhere, such as the military and the workplace. This volume presents the most recent experiments and clinical applications to provide missing information and insight into the unanswered questions of hair testing. Active researchers working in hair testing have contributed chapters to this book. New data, never before published, are incorporated into the text, so the reader receives cutting-edge information from experts in the field. This is must-have information on everything you need to know about drug testing in hair.

Fundamentals of Analytical Toxicology

Fundamentals of Analytical Toxicology
Author: Robert J. Flanagan
Publsiher: John Wiley & Sons
Total Pages: 505
Release: 2007
ISBN 10: 0470319348
ISBN 13: 9780470319345
Language: EN, FR, DE, ES & NL

Fundamentals of Analytical Toxicology Book Review:

The analytical toxicologist may be required to detect, identify, and in many cases measure a wide variety of compounds in samples from almost any part of the body or in related materials such as residues in syringes or in soil. This book gives principles and practical information on the analysis of drugs and poisons in biological specimens, particularly clinical and forensic specimens. After providing some background information the book covers aspects of sample collection, transport, storage and disposal, and sample preparation. Analytical techniques - colour tests and spectrophotometry, chromatography and electro­phoresis, mass spectrometry, and immunoassay ? are covered in depth, and a chapter is devoted to the analysis of trace elements and toxic metals. General aspects of method implementation/validation and laboratory operation are detailed, as is the role of the toxicology laboratory in validating and monitoring the performance of point of care testing (POCT) devices. The book concludes with reviews of xenobiotic absorption, distribution and metabolism, pharmacokinetics, and general aspects of the interpretation of analytical toxicology results. A clearly written, practical, integrated approach to the basics of analytical toxicology. Focuses on analytical, statistical and pharmacokinetic principles rather than detailed applications. Assumes only a basic knowledge of analytical chemistry. An accompanying website provides additional material and links to related sites. Written by an experienced team of authors,Fundamentals of Analytical Toxicology is an invaluable resource for those starting out in a career in analytical toxicology across a wide range of disciplines including clinical and forensic science, food safety, and pharmaceutical development. Praise from the reviews: ?This is an ambitious effort to describe in detail the many and varied aspects of the science of toxicological analysis. The 17 chapters cover every foreseeable aspect, from specimen collection through analytical techniques and quality control to pharmacological principles and interpretation of results. The authors bring together a great deal of experience in the field and have succeeded admirably in achieving their goal: "to give principles and practical information on the analysis of drugs, poisons and other relevant analytes in biological specimens...". The book is very readable and quite up-to-date, and contains many illustrative figures, charts and tables. Both the student and the practicing professional would do well to study this material carefully, as there is something here for every conceivable level of interest.? Review from Randall Baselt "This text comes highly recommended for any analytical toxicology trainee." The Bulletin of the Royal College of Pathologists ?Overall, this book provides a comprehensive, thorough, clear, up to date and practical treatment of analytical toxicology at a high standard. Understanding of the text is enhanced by the use of many illustrations. Specifications, guidelines, and methods are highlighted in grey background ?Boxes?. The many and up to date literature references in each chapter demonstrate the authors? thorough work and permit easy access to deeper information. Therefore this book can be highly recommended as a valuable source of knowledge in analytical toxicology both as an introduction and for the advanced reader.? GTFCh Bulletin ?Toxichem + Krimtech?, May 2008 (translated, original review in German) ?Many toxicologists will add this important reference to their libraries because it competently fills a need ...? International Journal of Toxicology ?The book is very well illustrated, easy to understand and pleasant to read, and contains a wealth of dedicated information.? International Journal of Environmental Analytical Chemistry

Clarke s Analytical Forensic Toxicology

Clarke s Analytical Forensic Toxicology
Author: Gail Cooper,Adam Negrusz
Publsiher: Pharmaceutical Press
Total Pages: 656
Release: 2013-05-28
ISBN 10: 0857110543
ISBN 13: 9780857110541
Language: EN, FR, DE, ES & NL

Clarke s Analytical Forensic Toxicology Book Review:

This second edition of Clarke's Analytical Forensic Toxicology offers a fresh perspective on the drugs and poisons that you are most likely to encounter in forensic toxicology, with a focus on collection, extraction and analysis. With additional features incorporated from the fourth edition of Clarke's Analysis of Drugs and Poisons this text is fully updated to reflect the advances in analytical and forensic toxicology. New and extended chapters include: sampling, storage and stability; in-utero exposure to drugs of abuse; drug-facilitated sexual assault; and extraction. Providing unrivalled comprehensive coverage of analytical forensic toxicology, this book is a crucial resource for students of forensic science, toxicology, clinical pharmacology and analytical chemistry. It is an invaluable tool for teachers in these subject areas and a key resource for those working in forensic science laboratories.

Analytical and Practical Aspects of Drug Testing in Hair

Analytical and Practical Aspects of Drug Testing in Hair
Author: Pascal Kintz
Publsiher: CRC Press
Total Pages: 382
Release: 2006-08-30
ISBN 10: 9781420006193
ISBN 13: 1420006193
Language: EN, FR, DE, ES & NL

Analytical and Practical Aspects of Drug Testing in Hair Book Review:

Many advances have been made since the publication of Drug Testing in Hair. The mid-1990s witnessed the progress in cannabis detection while the late 1990s focused on benzodiazepines detection and the applications in doping control. In more recent years, toxicologists centered on the detection in hair of a single exposure and the related applicatio

Forensic Toxicology

Forensic Toxicology
Author: David Holt
Publsiher: Royal Society of Chemistry
Total Pages: 578
Release: 2016-07-01
ISBN 10: 1782621563
ISBN 13: 9781782621560
Language: EN, FR, DE, ES & NL

Forensic Toxicology Book Review:

New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years. Forensic Toxicology: Drug Use and Misuse brings together the latest information direct from experts in each sub-field of the discipline providing a broad overview of current thinking and the most innovative approaches to case studies. The text begins with an in-depth discussion of pharmacoepidemiology, including information on the value of nationwide databases in forensic toxicology. The use and abuse of drugs in driving, sport and the workplace are then discussed by industry experts who are conducting case work in their field. Not only are new drug groups discussed (NPS), but also their constantly changing impact on drug legislation. Synthetic cannabinoids, khat and mephodrone are discussed in detail. Following a section devoted to legislation and defence, readers will find comprehensive chapters covering sample choice reflecting the increasing use of hair and oral fluid, and also the less commonly used sweat and nail analysis. New and old case examples are compared and contrasted in the final part of the book, which will enable readers to understand how drugs impact on each other and how the interpretative outcome of a case are dependent on many aspects. From use of pharmaceutical drugs in a clinical setting, through smart drugs to new psychoactive drugs, this book documents the wide range in which drugs today are abused. This book will be an essential resource for postgraduate students in forensic toxicology, and for researchers in forensic toxicology laboratories who need the latest data and knowledge.

Drug Testing in Hair

Drug Testing in Hair
Author: Pascal Kintz
Publsiher: CRC Press
Total Pages: 304
Release: 1996-05-07
ISBN 10: 9780849381126
ISBN 13: 0849381126
Language: EN, FR, DE, ES & NL

Drug Testing in Hair Book Review:

Drug Testing in Hair is the first book on this timely and controversial topic. The book's purpose is to validate hair testing as an accepted form of evidence for use in courts and elsewhere, such as the military and the workplace. This volume presents the most recent experiments and clinical applications to provide missing information and insight into the unanswered questions of hair testing. Active researchers working in hair testing have contributed chapters to this book. New data, never before published, are incorporated into the text, so the reader receives cutting-edge information from experts in the field. This is must-have information on everything you need to know about drug testing in hair.

Forensic Drug Analysis

Forensic Drug Analysis
Author: Future Science Ltd
Publsiher: Unknown
Total Pages: 125
Release: 2013
ISBN 10: 9781909453364
ISBN 13: 1909453366
Language: EN, FR, DE, ES & NL

Forensic Drug Analysis Book Review:

Toxicological Aspects of Drug Facilitated Crimes

Toxicological Aspects of Drug Facilitated Crimes
Author: Pascal Kintz
Publsiher: Elsevier
Total Pages: 312
Release: 2014-03-22
ISBN 10: 0124169694
ISBN 13: 9780124169692
Language: EN, FR, DE, ES & NL

Toxicological Aspects of Drug Facilitated Crimes Book Review:

Toxicological Aspects of Drug-Facilitated Crimes provides readers with an overview of the field of DFC: its history, toxicological effects, analysis, interpretation of results, the roles that age, gender and race may play, and clinical presentations of these drugs. The most commonly used drugs in DFC are addressed (alcohol, cannabis, MDMA, and cocaine), as well as an emerging range of pharmaceuticals (benzodiazepines, hypnotics, sedatives, neuroleptics, histamine H1-antagonists, or anesthetics), which are becoming more widely used, but are more difficult to detect. Edited by a world-renowned expert in the field of Forensic and Analytical Toxicology, Pascal Kintz, this book investigates toxicants of emerging concern and brings together a number of experts in the field to address the most recent discoveries on DFC toxicology. Brings together the latest research on the toxicological analysis of drug-facilitated crimes (DFC), with real-life case studies Provides up-to-date analytical techniques for determining toxicity levels in blood, urine, and hair Covers all types of toxicants involved in DFC, including alcohol, cannabis, MDMA, and a wide variety of pharmaceuticals

Poisoning

Poisoning
Author: Ntambwe Malangu
Publsiher: BoD – Books on Demand
Total Pages: 218
Release: 2017-12-20
ISBN 10: 953513681X
ISBN 13: 9789535136811
Language: EN, FR, DE, ES & NL

Poisoning Book Review:

This book, which is the result of contributions from a team of international authors, presents a collection of materials that can be categorized into two groups. The first group of papers deals with clinical toxicology topics including poisoning by anticoagulant rodenticides, food toxins, carbon monoxide, the toxicity of beta-lactam antibiotics, acute neonicotinoid poisoning, occupational risk factors for acute pesticide poisoning, activating carbon fibers, and date pits for use in liver toxin adsorption. The second group of papers deals with forensic or analytical toxicology topics such as simplified methods for the analysis of gaseous toxic agents, rapid methods for the analysis and monitoring of pathogens in drinking water and water-based solutions, as well as the linkages between clinical and forensic toxicology. Each chapter presents new information on the topic discussed based on authors' experience while summarizing existing knowledge. As such, this book will be a good teaching aid and can be a prescribed or recommended reading for postgraduate students and professionals in the fields of public health, medicine, pharmacy, nursing, biology, toxicology, and forensic sciences.

Critical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing
Author: Amitava Dasgupta
Publsiher: Academic Press
Total Pages: 560
Release: 2019-01-10
ISBN 10: 0128156082
ISBN 13: 9780128156087
Language: EN, FR, DE, ES & NL

Critical Issues in Alcohol and Drugs of Abuse Testing Book Review:

Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Principles of Forensic Toxicology

Principles of Forensic Toxicology
Author: Barry Levine
Publsiher: Amer. Assoc. for Clinical Chemistry
Total Pages: 385
Release: 2003
ISBN 10: 9781890883874
ISBN 13: 1890883875
Language: EN, FR, DE, ES & NL

Principles of Forensic Toxicology Book Review:

Forensic Toxicology

Forensic Toxicology
Author: Max M. Houck
Publsiher: Academic Press
Total Pages: 418
Release: 2018-01-02
ISBN 10: 0128008180
ISBN 13: 9780128008188
Language: EN, FR, DE, ES & NL

Forensic Toxicology Book Review:

Forensic Toxicology, the latest release in the Advanced Forensic Science Series that grew out of recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward will serve as a graduate level text for those studying and teaching forensic toxicology. It is also an excellent reference for the forensic practitioner’s library or for use in their casework. Coverage includes a wide variety of methods used, along with pharmacology and drugs and professional issues they may encounter. Edited by a world-renowned, leading forensic expert, this updated edition is a long overdue solution for the forensic science community. Provides basic principles of forensic science and an overview of forensic toxicology Contains information on a wide variety of methods Covers pharmacology and drugs, matrices and interpretation Includes a section on professional issues, such as crime scene to court, lab reports, health and safety, post-mortem and drug facilitated crimes Incorporates effective pedagogy, key terms, review questions, discussion questions and additional reading suggestions

Toxicology

Toxicology
Author: John Joseph Fenton
Publsiher: CRC Press
Total Pages: 600
Release: 2001-10-10
ISBN 10: 1420042068
ISBN 13: 9781420042061
Language: EN, FR, DE, ES & NL

Toxicology Book Review:

REAL-LIFE CASES, TUTORIAL QUESTIONS, NARRATIVE HISTORY Intriguing anecdotal pedagogy, like the alleged arsenical poisonings of Napoleon and President Taylor and the probable mercury overdose of Isaac Newton, is one of the things that set Toxicology: A Case-Oriented Approach apart from other toxicology texts. Based on an undergraduate-graduate combined toxicology course at West Chester University, this innovative text captures readers' interest by combining modern case studies, historical cases, and hundreds of illustrations and tables. Each chapter presents several case scenarios that involve the reader with questions about diagnosis, testing methods, treatment, and other pertinent information. TOXICOLOGY FOR THE LABORATORY AND THE EMERGENCY ROOM In an easy-to-read style, this book covers the major organ systems and reviews the effects of toxins in each system. Most contemporary books are almost entirely clinical or entirely analytical. Toxicology: A Case-Oriented Approach treats each area extensively to benefit students and professionals who need to know aspects of both. It describes diagnosis and treatment of each specific poisonous exposure and discusses chemical basis and the laboratory testing of toxins. This dual perspective, coupled with the book's interesting narrative approach, lets readers quickly absorb the information they need to understand toxicology in the laboratory and in the Emergency Department.

Molecular Clinical and Environmental Toxicology

Molecular  Clinical and Environmental Toxicology
Author: Andreas Luch
Publsiher: Springer Science & Business Media
Total Pages: 619
Release: 2010-03-01
ISBN 10: 3764383380
ISBN 13: 9783764383381
Language: EN, FR, DE, ES & NL

Molecular Clinical and Environmental Toxicology Book Review:

Clinical Toxicology is the second volume of a three-volume set on molecular, clinical and environmental toxicology that offers a comprehensive and in-depth response to the increasing importance and abundance of chemicals of daily life. By providing intriguing insights far down to the molecular level, this three-volume work covers the entire range of modern toxicology with special emphasis on recent developments and achievements. It is written for students and professionals in medicine, science, public health or engineering who are demanding reliable information on toxic or potentially harmful agents and their adverse effects on the human body.

Forensic Toxicological Aspects of Tramadol

Forensic Toxicological Aspects of Tramadol
Author: Pernilla Haage
Publsiher: Linköping University Electronic Press
Total Pages: 104
Release: 2018-11-09
ISBN 10: 9176851966
ISBN 13: 9789176851968
Language: EN, FR, DE, ES & NL

Forensic Toxicological Aspects of Tramadol Book Review:

One of the most difficult parts in forensic toxicology is to interpret obtained drug concentrations. Was it therapeutic, toxic or even lethal to the particular individual that the blood sample was drawn from? Concentrations of opioid drugs are especially difficult to interpret, because of large interindividual differences in innate and acquired tolerance. Tramadol is a complex drug. Not only is it an opioid, it is also a racemic drug with the (+)- and (-)-enantiomers of the parent compound and metabolites showing different pharmacological effects. Further, it is metabolized by polymorphic enzymes, which may affect the amounts of metabolites formed and possibly the enantiomer ratios of the parent compound and its metabolites. It has been speculated that particularly the (+)/(-)-enantiomer ratio of O-desmethyltramadol is related to the risk of adverse effects, and it has been shown that the ratio is affected by CYP2D6 genotype. The overall aim of the thesis was to evaluate if forensic interpretations of tramadol, regarding toxicity and time since drug administration, may be improved by the use of genotyping and enantioselective concentration determination of tramadol and its three main metabolites. To simultaneously quantify the enantiomer concentrations of tramadol, Odesmethyltramadol, N-desmethyltramadol and N,O-didesmethyltramadol in whole blood, a liquid chromatography tandem mass spectrometry (LCMS/MS) method was developed and validated. Genetic variation in CYP2D6, CYP2B6, CYP3A4 (encoding the tramadol metabolizing enzymes), ABCB1 (encoding a transport protein) and OPRM1 (encoding the ?-opioid receptor) was investigated, using pyrosequencing, xTAG, and TaqMan analysis. The methods were applied to the blood samples of two study populations; 19 healthy volunteers administered a therapeutic, single tramadol dose, and 159 tramadol positive autopsy cases. The most important finding was the positive correlations between all four enantiomer ratios and time since tramadol administration in the healthy volunteers. All enantiomer ratios except the one of tramadol was also affected by the CYP2D6 genotype, which was apparent among the autopsy cases as well. Genetic variation in CYP2D6 and possibly CYP2B6 was shown to have an impact on tramadol pharmacokinetics, although no association to neither drug related symptoms nor tramadol related causes of death was found. Tramadol intoxications were predominantly characterized by low age (median 26 years) and male sex, often with a history of substance abuse and with other drugs (at fairly low concentrations) detected in blood. In conclusion, enantiomer concentration determination combined with genotyping seems promising regarding estimations of time since drug administration, although is of low value concerning interpretations of toxicity in autopsy cases.

Forensic Issues in Alcohol Testing

Forensic Issues in Alcohol Testing
Author: Steven B. Karch, MD, FFFLM
Publsiher: CRC Press
Total Pages: 154
Release: 2016-04-19
ISBN 10: 9781420054460
ISBN 13: 1420054465
Language: EN, FR, DE, ES & NL

Forensic Issues in Alcohol Testing Book Review:

Extracted from the Drug Abuse Handbook, 2nd edition, to give you just the information you need at an affordable price. Forensic Issues in Alcohol Testing offers concise and focused information specific to the interests of forensic scientists and clinical and forensic toxicologists. It analyzes the acute effects of alcohol intoxication and the methods by which investigators can measure alcohol concentration in blood, urine, and breath. It considers extenuating circumstances affecting acute impairment by detailing the disposition and fate of alcohol in the body as well as the factors influencing absorption, distribution, and elimination. Specific chapters address difficulties in measuring and interpreting post-mortem alcohol concentrations due to poor quality of specimen, sampling site differences, and post-mortem diffusion or synthesis. Recent advances in biochemical testing make it possible to quantitate chronic alcohol ingestion, and the book analyzes the efficacy of these tests as evaluators of dependence or potential for dependence.

P5 Medicine and Justice

P5 Medicine and Justice
Author: Santo Davide Ferrara
Publsiher: Springer
Total Pages: 635
Release: 2018-03-27
ISBN 10: 3319670921
ISBN 13: 9783319670928
Language: EN, FR, DE, ES & NL

P5 Medicine and Justice Book Review:

This book describes the state of the art and future prospects of the most important bio-medicolegal subdisciplines in the post-genomic framework of personalized medicine. Focusing on the three main themes Innovation, Unitariness and Evidence, the book addresses a wide range of topics, including: Bio-Medicolegal and Criminological Sciences, Forensic Pathology and Anthropology, Clinical and Forensic Medicine in Living Persons (from Interpersonal Violence to Personal Injury and Damage, Malpractice, Personal Identification and Age Estimation), Forensic Genetics and Genomics, and Toxicology and Imaging. The unitariness of the “Bio-Medicolegal Sciences”, historically founded on the accuracy and rigor of the methods of ascertainment and criteria of evaluation, should be re-established on the basis of molecular evidence, and used to promote Personalized Justice. Taken together, the book’s conclusions and future perspectives outline a vision of transdisciplinary innovation and future evidence in the framework of personalized justice.

Handbook of Forensic Drug Analysis

Handbook of Forensic Drug Analysis
Author: Fred Smith
Publsiher: Elsevier
Total Pages: 584
Release: 2004-12-31
ISBN 10: 9780080472898
ISBN 13: 0080472893
Language: EN, FR, DE, ES & NL

Handbook of Forensic Drug Analysis Book Review:

The Handbook of Forensic Drug Analysis is a comprehensive chemical and analytic reference for the forensic analysis of illicit drugs. With chapters written by leading researchers in the field, the book provides in-depth, up-to-date methods and results of forensic drug analyses. This Handbook discusses various forms of the drug as well as the origin and nature of samples. It explains how to perform various tests, the use of best practices, and the analysis of results. Numerous forensic and chemical analytic techniques are covered including immunoassay, gas chromatography, and mass spectrometry. Topics range from the use of immunoassay technologies for drugs-of-abuse testing, to methods of forensic analysis for cannabis, hallucinogens, cocaine, opioids, and amphetamine. The book also looks at synthetic methods and law enforcement concerns regarding the manufacture of illicit drugs, with an emphasis on clandestine methamphetamine production. This Handbook should serve as a widely used reference for forensic scientists, toxicologists, pharmacologists, drug companies, and professionals working in toxicology testing labs, libraries, and poison control centers. It may also be used by chemists, physicians and those in legal and regulatory professions, and students of graduate courses in forensic science. Contributed to by leading scientists from around the world The only analysis book dedicated to illicit drugs of abuse Comprehensive coverage of sampling methods and various forms of analysis

Detection of Drugs and Their Metabolites in Oral Fluid

Detection of Drugs and Their Metabolites in Oral Fluid
Author: Robert M. White,Christine M. Moore
Publsiher: Elsevier
Total Pages: 140
Release: 2018-02-23
ISBN 10: 012814596X
ISBN 13: 9780128145968
Language: EN, FR, DE, ES & NL

Detection of Drugs and Their Metabolites in Oral Fluid Book Review:

Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends. This volume covers the salient aspects of oral fluid drug testing, including specimen collection and handling, initial testing, point of collection testing (POCT), specimen validity testing (SVT), and confirmatory and proficiency testing. Analytes discussed include amphetamines, cannabinoids, cocaine, opiates, phencyclidine, cannabimimetics, and miscellaneous drugs. This practical guide helps users turn knowledge into practice, moving logically from an outline of the problem, to the evaluation of the appropriateness of oral fluid as a test medium, and finally to a consideration of detection methods and their validation and employment. Compares different collection and testing systems to assist readers involved in clinical or forensic practice in selecting oral fluid as the matrix of choice Provides a sound basis for the detection of drugs and their metabolites in oral fluid and the interpretation of both positive and negative Places the need, or lack thereof, for specimen validity testing and confirmation testing in context with the purposes of oral fluid testing Describes drugs and drug classes that can be tested, along with useful information on a patient/donor’s drug status