Green Approaches in Medicinal Chemistry for Sustainable Drug Design

Green Approaches in Medicinal Chemistry for Sustainable Drug Design
Author: Bimal K. Banik
Publsiher: Elsevier
Total Pages: 1044
Release: 2020-03-27
ISBN 10: 0128175931
ISBN 13: 9780128175934
Language: EN, FR, DE, ES & NL

Green Approaches in Medicinal Chemistry for Sustainable Drug Design Book Review:

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6. Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability Reflects on techniques for a broad range of compounds and materials Highlights sustainable and green chemistry pathways for molecular synthesis

Contemporary Chemical Approaches for Green and Sustainable Drugs

Contemporary Chemical Approaches for Green and Sustainable Drugs
Author: Marianna Torok
Publsiher: Elsevier
Total Pages: 500
Release: 2022-03-15
ISBN 10: 9780128222485
ISBN 13: 0128222484
Language: EN, FR, DE, ES & NL

Contemporary Chemical Approaches for Green and Sustainable Drugs Book Review:

Contemporary Chemical Approaches for Green and Sustainable Drugs provides readers with the knowledge they need to integrate sustainable approaches into their work. Sections cover different aspects of green and sustainable drug development from design to disposal, including computer-aided drug design, green resourcing of drugs and drug candidates, an overview of the health concerns of pharmaceutical pollution, and a survey of potential chemical methods for its reduction. Drawing together the knowledge of a global team of experts, this book provides an inclusive overview of the chemical tools and approaches available for minimizing the negative environmental impact of current and newly developed drugs. This will be a useful guide for all academic and industrial researchers across green and sustainable chemistry, medicinal chemistry, environmental chemistry and pharmaceutical science. Provides an integrative overview of the environmental risks of drugs and drug by products to support chemists in pre-emptively addressing these issues Highlights the advantages of computer-aided drug design, green and sustainable sourcing, and novel methods for the production of safer, more effective drugs Presents individual chapters written by renowned experts with diverse backgrounds Reflects research in practice through selected case studies and extensive state-of-the-art reference sections to serve as a starting point in the design of any specialized environmentally-conscious medicinal chemistry project

Green Chemistry Strategies for Drug Discovery

Green Chemistry Strategies for Drug Discovery
Author: Emily A. Peterson,Julie B. Manley
Publsiher: Royal Society of Chemistry
Total Pages: 322
Release: 2015-06-11
ISBN 10: 1782622659
ISBN 13: 9781782622659
Language: EN, FR, DE, ES & NL

Green Chemistry Strategies for Drug Discovery Book Review:

The incorporation of Green Chemistry is a relatively new phenomenon in the drug discovery discipline, since the scale that chemists operate on in drug discovery is smaller than those of process and manufacturing chemistry. The necessary metrics are more difficult to obtain in drug discovery due to the diversity of reactions conducted. However, pharmaceutical companies are realizing that incorporation of green chemistry techniques at earlier stages of drug development can speed the development of a drug candidate. Written by experts who have pioneered green chemistry efforts within their own institutions, this book provides a practical guide for both academic and industrial labs wanting to know where to start with introducing greener approaches for greatest return on investment. The Editors have taken a comprehensive approach to the topic, covering the entire drug discovery process from molecule conception, through synthesis, formulation and toxicology with specific examples and case studies where green chemistry strategies have been implemented. Emerging techniques for performing greener drug discovery chemistry are addressed as well as cutting-edge topics like biologics discovery and continuous processing. Moreover, important surrounding issues such as intellectual property are included. This book serves as a practical guide for both academic and industrial chemists who work across the breadth of the drug discovery discipline. Ultimately, readers will learn how to incorporate green chemistry strategies into their everyday workflow without slowing down their science.

Green Sustainable Process for Chemical and Environmental Engineering and Science

Green Sustainable Process for Chemical and Environmental Engineering and Science
Author: Dr Inamuddin,Rajender Boddula,Abdullah M. Asiri
Publsiher: Elsevier
Total Pages: 240
Release: 2021-11-26
ISBN 10: 0128198516
ISBN 13: 9780128198513
Language: EN, FR, DE, ES & NL

Green Sustainable Process for Chemical and Environmental Engineering and Science Book Review:

Green Sustainable Process for Chemical and Environmental Engineering and Science: Switchable Solvents explores the preparation, properties, chemical processes and applications of this class of green solvents. The book provides an in-depth overview on the area of switchable solvents in various industrial applications, focusing on the purification and extraction of chemical compounds utilizing green chemistry protocols that include liquid-liquid, solid-liquid, liquid-gas and lipids separation technologies. In addition, it includes recent advances in greener extraction and separation processes. This book will be an invaluable guide to students, professors, scientists and R&D industrial specialists working in the field of sustainable chemistry, organic, analytical, chemical engineering, environmental and pharmaceutical sciences. Provides a broad overview of switchable solvents in sustainable chemical processes Compares the use of switchable solvents as greener solvents over conventional solvents Outlines eco-friendly organic synthesis and chemical processes using switchable solvents Lists various industrial separations/extraction processes using switchable solvents

Green Chemistry

Green Chemistry
Author: Tatsiana Savitskaya,Iryna Kimlenka,Yin Lu,Dzmitry Hrynshpan,Valentin Sarkisov,Jie Yu,Nabo Sun,Shilei Wang,Wei Ke,Li Wang
Publsiher: Springer Nature
Total Pages: 156
Release: 2021
ISBN 10: 9811637466
ISBN 13: 9789811637469
Language: EN, FR, DE, ES & NL

Green Chemistry Book Review:

This book investigates in detail the concepts and principles of green chemistry and related methodologies, including green synthesis, green activation methods, green catalysis, green solvents, and green design to achieve process intensification while at the same time ensuring process safety and promoting ecological civilization and environmental protection. Moreover, it incorporates elements of chemical management and chemical education, highlighting chemists' responsibility to protect humankind and foster green and sustainable development in chemistry. Combining Chinese and Belarus wisdom, this book is intended for those working in the chemical industry who are interested in environmental protection and sustainable development, as well as undergraduate and graduate students who are interested in green chemistry and related technologies.

Green Techniques for Organic Synthesis and Medicinal Chemistry

Green Techniques for Organic Synthesis and Medicinal Chemistry
Author: Wei Zhang,Berkeley Cue
Publsiher: John Wiley & Sons
Total Pages: 728
Release: 2018-03-26
ISBN 10: 1119288169
ISBN 13: 9781119288169
Language: EN, FR, DE, ES & NL

Green Techniques for Organic Synthesis and Medicinal Chemistry Book Review:

Green Techniques FOR Organic Synthesis AND Medicinal Chemistry An updated overview of the rapidly developing field of green techniques for organic synthesis and medicinal chemistry Green chemistry remains a high priority in modern organic synthesis and pharmaceutical R&D, with important environmental and economic implications. This book presents comprehensive coverage of green chemistry techniques for organic and medicinal chemistry applications, summarizing the available new technologies, analyzing each technique's features and green chemistry characteristics, and providing examples to demonstrate applications for green organic synthesis and medicinal chemistry. The extensively revised edition of Green Techniques for Organic Synthesis and Medicinal Chemistry includes 7 entirely new chapters on topics including green chemistry and innovation, green chemistry metrics, green chemistry and biological drugs, and the business case for green chemistry in the generic pharmaceutical industry. It is divided into 4 parts. The first part introduces readers to the concepts of green chemistry and green engineering, global environmental regulations, green analytical chemistry, green solvents, and green chemistry metrics. The other three sections cover green catalysis, green synthetic techniques, and green techniques and strategies in the pharmaceutical industry. Includes more than 30% new and updated material—plus seven brand new chapters Edited by highly regarded experts in the field (Berkeley Cue is one of the fathers of Green Chemistry in Pharma) with backgrounds in academia and industry Brings together a team of international authors from academia, industry, government agencies, and consultancies (including John Warner, one of the founders of the field of Green Chemistry) Green Techniques for Organic Synthesis and Medicinal Chemistry, 2nd Edition is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in organic chemistry and medicinal chemistry.

Green Synthetic Approaches for Biologically Relevant Heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles
Author: Goutam Brahmachari
Publsiher: Elsevier
Total Pages: 646
Release: 2021-03-20
ISBN 10: 0323851304
ISBN 13: 9780323851305
Language: EN, FR, DE, ES & NL

Green Synthetic Approaches for Biologically Relevant Heterocycles Book Review:

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability

Green and Sustainable Medicinal Chemistry

Green and Sustainable Medicinal Chemistry
Author: Louise Summerton,Helen F. Sneddon,Leonie C. Jones,James H. Clark
Publsiher: Royal Society of Chemistry
Total Pages: 272
Release: 2016
ISBN 10: 1782624678
ISBN 13: 9781782624677
Language: EN, FR, DE, ES & NL

Green and Sustainable Medicinal Chemistry Book Review:

Green Chemistry in the Pharmaceutical Industry

Green Chemistry in the Pharmaceutical Industry
Author: Peter J. Dunn,Andrew Wells,Michael T. Williams
Publsiher: John Wiley & Sons
Total Pages: 388
Release: 2010-02-02
ISBN 10: 9783527629695
ISBN 13: 3527629696
Language: EN, FR, DE, ES & NL

Green Chemistry in the Pharmaceutical Industry Book Review:

Edited by three of the world's leading pharmaceutical scientists, this is the first book on this important and hot topic, containing much previously unpublished information. As such, it covers all aspects of green chemistry in the pharmaceutical industry, from simple molecules to complex proteins, and from drug discovery to the fate of pharmaceuticals in the environment. Furthermore, this ready reference contains several convincing case studies from industry, such as Taxol, Pregabalin and Crestor, illustrating how this multidisciplinary approach has yielded efficient and environmentally-friendly processes. Finally, a section on technology and tools highlights the advantages of green chemistry.

Sustainable Synthesis of Pharmaceuticals

Sustainable Synthesis of Pharmaceuticals
Author: Mariette M. Pereira,Mario J. F. Calvete
Publsiher: Royal Society of Chemistry
Total Pages: 286
Release: 2018-03-26
ISBN 10: 1788010655
ISBN 13: 9781788010658
Language: EN, FR, DE, ES & NL

Sustainable Synthesis of Pharmaceuticals Book Review:

There is a growing interest in the development of sustainable processes for the synthesis of pharmaceuticals and this book bridges the divide between industrial examples and the fundamental chemistry. It explains the basic principles of using transition metal catalysis with several green approaches for the synthesis of pharmaceuticals. The topic is an important one for green chemistry and the chapters in this book on hydroformylation, green oxidation and olefin metathesis will also be of interest to both medicinal and organic chemists. Written by leading experts in the field, it provides a valuable and easy tool for scientists and industrialists who require information regarding this topic.

Green and Sustainable Pharmacy

Green and Sustainable Pharmacy
Author: Klaus Kümmerer,Maximilian Hempel
Publsiher: Springer Science & Business Media
Total Pages: 313
Release: 2010-06-16
ISBN 10: 3642051995
ISBN 13: 9783642051999
Language: EN, FR, DE, ES & NL

Green and Sustainable Pharmacy Book Review:

Within recent years pharmaceuticals have come into focus as contaminants of the environment (see for example Kümmerer, K. editor: Pharmaceuticals in the Environment). At the same time the issue of sustainable chemistry gained momentum. Bringing both together would result in sustainable pharmacy. Sustainable pharmacy is a totally new issue and approach. It addresses environmental, economical and social aspects of pharmacy. In the present stage the focus will be on environmental issues along the whole lifecycle of a pharmaceutical entity. That is dealing with resources and energy input but also with waste issues for example during the synthesis and production of an active pharmaceutical ingredient. Furthermore, it would also look on the compounds themselves and will aim to improve the degradability of the compounds after their use in the environment to reduce the environmental risk caused by pharmaceuticals in the environment. Another issue is the people using pharmaceuticals such as pharmacists, medical doctors and patients. How can they contribute to more efficient use of pharmaceuticals with less environmental burden and less risk for drinking water. The book "Sustainable Pharmacy" will address all these issues and will be the first one dealing with this important topic.

Process Chemistry in the Pharmaceutical Industry

Process Chemistry in the Pharmaceutical Industry
Author: Kumar Gadamasetti
Publsiher: CRC Press
Total Pages: 500
Release: 1999-05-06
ISBN 10: 9780824719814
ISBN 13: 0824719816
Language: EN, FR, DE, ES & NL

Process Chemistry in the Pharmaceutical Industry Book Review:

Providing guidance for chemists and other scientists entering pharmaceutical discovery and development, this up-to-the-minute reference presents contributions from an international group of nearly 50 renowned researchers—offering a solid grounding in synthetic and physical organic chemistry, and clarifying the roles of various specialties in the development of new drugs. Featuring over 1000 references, tables, and illustrations, Process Chemistry in the Pharmaceutical Industry is sure to find its way to the bookshelves of organic, physical, analytical, process, and medicinal chemists and biochemists; pharmacists; and upper-level undergraduate and graduate students in these disciplines.

Applications of Nanotechnology for Green Synthesis

Applications of Nanotechnology for Green Synthesis
Author: Inamuddin,Abdullah M. Asiri
Publsiher: Springer Nature
Total Pages: 499
Release: 2020-07-02
ISBN 10: 3030441768
ISBN 13: 9783030441760
Language: EN, FR, DE, ES & NL

Applications of Nanotechnology for Green Synthesis Book Review:

Traditional methods in synthetic chemistry produce chemical waste and byproducts, yield smaller desired products, and generate toxic chemical substances, but the past two centuries have seen consistent, greener improvements in organic synthesis and transformations. These improvements have contributed to substance handling efficiency by using green-engineered forerunners like sustainable techniques, green processes, eco-friendly catalysis, and have minimized energy consumption, reduced potential waste, improved desired product yields, and avoided toxic organic precursors or solvents in organic synthesis. Green synthesis has the potential to have a major ecological and monetary impact on modern pharmaceutical R&D and organic chemistry fields. This book presents a broad scope of green techniques for medicinal, analytical, environmental, and organic chemistry applications. It presents an accessible overview of new innovations in the field, dissecting the highlights and green chemistry attributes of approaches to green synthesis, and provides cases to exhibit applications to pharmaceutical and organic chemistry. Although daily chemical processes are a major part of the sustainable development of pharmaceuticals and industrial products, the resulting environmental pollution of these processes is of worldwide concern. This edition discusses green chemistry techniques and sustainable processes involved in synthetic organic chemistry, natural products, drug syntheses, as well various useful industrial applications.

Protecting Group Free Organic Synthesis

Protecting Group Free Organic Synthesis
Author: Rodney A. Fernandes
Publsiher: John Wiley & Sons
Total Pages: 288
Release: 2018-08-20
ISBN 10: 1119295203
ISBN 13: 9781119295204
Language: EN, FR, DE, ES & NL

Protecting Group Free Organic Synthesis Book Review:

Presents a comprehensive account of established protecting-group-free synthetic routes to molecules of medium to high complexity This book supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and back the global need of practicing green chemistry. The only resource of its kind to focus entirely on protecting-group-free synthesis, it is edited by a leading practitioner in the field, and features enlightening contributions by top experts and researchers from across the globe. The introductory chapter includes a concise review of historical developments, and discusses the concepts, need for, and future prospects of protecting-group-free synthesis. Following this, the book presents information on protecting-group-free synthesis of complex natural products and analogues, heterocycles, drugs, and related pharmaceuticals. Later chapters discuss practicing protecting-group-free synthesis using carbohydrates and of glycosyl derivatives, glycol-polymers and glyco-conjugates. The book concludes with a chapter on latent functionality as a tactic toward formal protecting-group-free synthesis. A comprehensive account of established protecting-group-free (PGF) synthetic routes to molecules of medium to high complexity Benefits total synthesis, methodology development and drug synthesis researchers Supports synthetic chemists in the design of strategies, which avoid or minimize the use of protecting groups so as to come closer to achieving an “ideal synthesis” and support the global need of practicing green chemistry Covers a topic that is gaining importance because it renders syntheses more economical Protecting-Group-Free Organic Synthesis: Improving Economy and Efficiency is an important book for academic researchers in synthetic organic chemistry, green chemistry, medicinal and pharmaceutical chemistry, biochemistry, and drug discovery.

Green Toxicology

Green Toxicology
Author: Alexandra Maertens
Publsiher: Unknown
Total Pages: 350
Release: 2021-08-25
ISBN 10: 9781839162282
ISBN 13: 1839162287
Language: EN, FR, DE, ES & NL

Green Toxicology Book Review:

Green Toxicology is an integral part of Green Chemistry. One of the key goals of Green Chemistry is to design less toxic chemicals. Therefore, an understanding of toxicology and hazard assessment is important for any chemist working in Green Chemistry, but toxicology is rarely part of most chemists' education. As a consequence, chemists lack the toxicological lens necessary to view chemicals in order to design safer substitutions. This book seeks to fill that gap and demonstrate how a basic understanding of toxicology, as well as the tools of in silico and in vitro toxicology, can be an integral part of Green Chemistry. R&D chemists, product stewards, and toxicologists who work in the field of sustainability, can all benefit from integrating Green Toxicology principles into their work. Topics include in silico tools for hazard assessment, toxicity testing, and lifecycle considerations, this book aims to act as a bridge between green toxicologists and green chemists.

Drug Design

Drug Design
Author: Royal society of chemistry (GB).
Publsiher: Royal Society of Chemistry
Total Pages: 192
Release: 2002
ISBN 10: 9780854048168
ISBN 13: 0854048162
Language: EN, FR, DE, ES & NL

Drug Design Book Review:

Providing details of state-of-the-art research, Drug Design: Cutting Edge Approaches will be invaluable to all drug discovery scientists.

Artificial Intelligence in Drug Discovery

Artificial Intelligence in Drug Discovery
Author: Nathan Brown
Publsiher: Royal Society of Chemistry
Total Pages: 406
Release: 2020-11-11
ISBN 10: 1839160543
ISBN 13: 9781839160547
Language: EN, FR, DE, ES & NL

Artificial Intelligence in Drug Discovery Book Review:

Following significant advances in deep learning and related areas interest in artificial intelligence (AI) has rapidly grown. In particular, the application of AI in drug discovery provides an opportunity to tackle challenges that previously have been difficult to solve, such as predicting properties, designing molecules and optimising synthetic routes. Artificial Intelligence in Drug Discovery aims to introduce the reader to AI and machine learning tools and techniques, and to outline specific challenges including designing new molecular structures, synthesis planning and simulation. Providing a wealth of information from leading experts in the field this book is ideal for students, postgraduates and established researchers in both industry and academia.

Green Sustainable Process for Chemical and Environmental Engineering and Science

Green Sustainable Process for Chemical and Environmental Engineering and Science
Author: Dr Inamuddin,Rajender Boddula,Mohd Ahamed,Abdullah M. Asiri
Publsiher: Elsevier
Total Pages: 374
Release: 2020-11-18
ISBN 10: 0128218991
ISBN 13: 9780128218990
Language: EN, FR, DE, ES & NL

Green Sustainable Process for Chemical and Environmental Engineering and Science Book Review:

Green Sustainable Process for Chemical and Environmental Engineering and Science: Solvents for the Pharmaceutical Industry aims at providing a detailed overview of applications of green solvents in pharmaceutical industries. It also focuses on providing a detailed literature survey on the green solvents for pharmaceutical analysis, drug design, synthesis, and production, etc. It summarizes the applications of various greens solvents such as water, cyrene, vegetable oils, ionic liquids, ethyl lactate, eutectic solvents, and glycerol in contrast to toxic solvents. This book provides an overview of the use of green solvents for the sustainable and environmentally friendly development of synthetic methodologies for biomedical and pharmaceutical industries. Up-to-date developments towards the development of solvents for pharmaceutical industry Includes latest advances in pharmaceutical analysis and synthesis using green solvents Outlines eco-friendly green solvents for medicinal applications State-of-the-art overview on the exploration of green solvents for pharmaceutical industries

Computational Drug Design

Computational Drug Design
Author: D. C. Young
Publsiher: John Wiley & Sons
Total Pages: 344
Release: 2009-01-28
ISBN 10: 9780470451847
ISBN 13: 047045184X
Language: EN, FR, DE, ES & NL

Computational Drug Design Book Review:

Helps you choose the right computational tools and techniques to meet your drug design goals Computational Drug Design covers all of the major computational drug design techniques in use today, focusing on the process that pharmaceutical chemists employ to design a new drug molecule. The discussions of which computational tools to use and when and how to use them are all based on typical pharmaceutical industry drug design processes. Following an introduction, the book is divided into three parts: Part One, The Drug Design Process, sets forth a variety of design processes suitable for a number of different drug development scenarios and drug targets. The author demonstrates how computational techniques are typically used during the design process, helping readers choose the best computational tools to meet their goals. Part Two, Computational Tools and Techniques, offers a series of chapters, each one dedicated to a single computational technique. Readers discover the strengths and weaknesses of each technique. Moreover, the book tabulates comparative accuracy studies, giving readers an unbiased comparison of all the available techniques. Part Three, Related Topics, addresses new, emerging, and complementary technologies, including bioinformatics, simulations at the cellular and organ level, synthesis route prediction, proteomics, and prodrug approaches. The book's accompanying CD-ROM, a special feature, offers graphics of the molecular structures and dynamic reactions discussed in the book as well as demos from computational drug design software companies. Computational Drug Design is ideal for both students and professionals in drug design, helping them choose and take full advantage of the best computational tools available. Note: CD-ROM/DVD and other supplementary materials are not included as part of eBook file.

Microwave Heating as a Tool for Sustainable Chemistry

Microwave Heating as a Tool for Sustainable Chemistry
Author: Nicholas E. Leadbeater
Publsiher: CRC Press
Total Pages: 290
Release: 2010-09-02
ISBN 10: 9781439812709
ISBN 13: 1439812705
Language: EN, FR, DE, ES & NL

Microwave Heating as a Tool for Sustainable Chemistry Book Review:

Shorter reaction times, higher product yields, and enhanced selectivity are some of the advantages microwave heating has over conventional methods, causing its use to transition from a curiosity to mainstream, both in industrial and academic settings. Microwave Heating as a Tool for Sustainable Chemistry showcases the application of microwave heati