Phosphate Metabolism

Phosphate Metabolism
Author: Shaul Massry
Publsiher: Springer Science & Business Media
Total Pages: 636
Release: 2013-11-21
ISBN 10: 1461342171
ISBN 13: 9781461342175
Language: EN, FR, DE, ES & NL

Phosphate Metabolism Book Review:

We present to our readers the proceedings of the Second International Workshop on Phosphate. A short account of the history of the effort led to the Phosphate Workshops is appro priate and can be of interest to the reader. The idea for Phosphate Workshops was born in the early days of November, 1974. One of us (S. G. M. ) suggested the thought to a group of scientists gathered for a luncheon in one of the attrac tive small restaurants in Weisbaden, Germany. The purpose of the workshop was to bring together interested scientists to discuss the newer developments and the recent advances in the field of phosphate metabolism and the other related minerals. An Organizing Committee made of Shaul G. Massry (USA), Louis V. Avioli (USA), Philippe Bordier (France), Herbert Fleisch (Switzerland), and Eduardo Slatopolsky (USA) was formed. The First Workshop was held in Paris during June 5-6, 1975 and was hosted by Dr. Philippe Bordier. Its proceeding was already published. The Second Workshop took place in Heidelberg during June 28-30, 1976 and was hosted by Dr. Eberhard Ritz. Both of these workshops were extremely successful scientific endeavors, and the need for them was demonstrated by the great interest they generated among the scientific community. The Or ganizing Committee, therefore, decided to continue with the tradi tion to hold additional Workshops annually or every other year.

Endocrine and Paracrine Role of FGF23 and Klotho in Health and Disease

Endocrine and Paracrine Role of FGF23 and Klotho in Health and Disease
Author: Reinhold G. Erben,L. Darryl Quarles
Publsiher: Frontiers Media SA
Total Pages: 329
Release: 2019-04-05
ISBN 10: 2889458059
ISBN 13: 9782889458059
Language: EN, FR, DE, ES & NL

Endocrine and Paracrine Role of FGF23 and Klotho in Health and Disease Book Review:

αKlotho and fibroblast growth factor-23 (FGF23) were discovered independently about 20 years ago. Since their initial description, a series of exciting discoveries have revealed the important role of endocrine and paracrine FGF23 and αKlotho signaling not only for the physiological regulation of mineral and bone homeostasis, but also for the pathophysiology of diseases such as chronic kidney disease, left ventricular hypertrophy, myocardial infarction, hypertension, and disorders characterized by impaired bone mineralization. The 11 articles compiled in this Research Topic consist of three Original Research articles and 8 Reviews or Mini Reviews, and are an excellent source of information about the state of the art in the FGF23/αKlotho field, covering almost all aspects of FGF23/αKlotho biology.

Encyclopedia of Signaling Molecules

Encyclopedia of Signaling Molecules
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 19??
ISBN 10: 9781461464389
ISBN 13: 1461464382
Language: EN, FR, DE, ES & NL

Encyclopedia of Signaling Molecules Book Review:

Endocrine FGFs and Klothos

Endocrine FGFs and Klothos
Author: Makoto Kuro-o
Publsiher: Springer Science & Business Media
Total Pages: 210
Release: 2012-03-06
ISBN 10: 1461408873
ISBN 13: 9781461408871
Language: EN, FR, DE, ES & NL

Endocrine FGFs and Klothos Book Review:

Fibroblast growth factors (FGFs) have been recognized primarily as autocrine/paracrine factors that regulate embryonic development and organogenesis. However, recent studies have revealed that some FGFs function as endocrine factors and regulate various metabolic processes in adulthood. Such FGFs, collectively called endocrine FGFs, are comprised of three members (FGF15/19, FGF21, and FGF23: FGF15 is the mouse ortholog of human FGF19). These endocrine FGFs share a common structural feature that enables the endocrine mode of action at the expense of the affinity to FGF receptors. To restore the affinity to FGF receptors in their target organs, the endocrine FGFs have designated the Klotho family of transmembrane proteins as obligate co-receptors. By expressing Klothos in a tissue-specific manner, this unique co-receptor system also enables the endocrine FGFs to specify their target organs among many tissues that express FGF receptors.

Current Perspectives in Kidney Diseases

Current Perspectives in Kidney Diseases
Author: G. La Manna,C. Ronco
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 200
Release: 2017-05-23
ISBN 10: 3318060615
ISBN 13: 9783318060614
Language: EN, FR, DE, ES & NL

Current Perspectives in Kidney Diseases Book Review:

After years of stagnation, much has been happening in the diagnosis and treatment of kidney diseases. This book contains a comprehensive review of the main developments in AKI, CKD, hemodialysis and kidney transplantation. The section on AKI deals with the key innovations in extracorporeal technologies. The section on nephrology and CKD concentrates on mineral metabolism alterations, restenosis in hemodialytic fistulas, mycophenolate mofetil as an alternative treatment for IgA nephropathy, and the genetics and progression of autosomal dominant polycystic kidney disease. The part on hemodialysis includes contributions on expanded hemodialysis, potassium profiling and home hemodialysis. Chapters on the treatment of acute antibody-mediated rejection after transplantation, pathogenesis and therapy of chronic allograft injury, and non-invasive surrogate biomarkers of acute rejection round out the subjects covered. Due to the wide variety of topics included in each section, this book is not only of interest to nephrologists, but also to professionals from related fields.

Nutritional Management of Renal Disease

Nutritional Management of Renal Disease
Author: Joel D. Kopple,Shaul G Massry,Kamyar Kalantar-Zadeh
Publsiher: Academic Press
Total Pages: 816
Release: 2012-12-31
ISBN 10: 0123919355
ISBN 13: 9780123919359
Language: EN, FR, DE, ES & NL

Nutritional Management of Renal Disease Book Review:

This translational text offers in-depth reviews of the metabolic and nutritional disorders that are prevalent in patients with renal disease. Chapter topics address the growing epidemic of obesity and metabolic syndrome. Each chapter integrates basic and clinical approaches, from cell biology and genetics to diagnosis, patient management and treatment. Chapters in sections 4-7 include new illustrative case reports, and all chapters emphasize key concepts with chapter-ending summaries. New features also include the latest National Kidney Foundation Clinical Practice Guidelines on Nutrition in Chronic Renal Failure, the most recent scientific discoveries and the latest techniques for assessing nutritional status in renal disease, and literature reviews on patients who receive continuous veno-venous hemofiltration with or without dialysis. Provides a common language for nephrologists, nutritionists, endocrinologists, and other interested physicians to discuss the underlying research and translation of best practices for the nutritional management and prevention of renal disease Saves clinicians and researchers time in quickly accessing the very latest details on nutritional practice as opposed to searching through thousands of journal articles Correct diagnosis (and therefore correct treatment) of renal, metabolic, and nutritional disorders depends on a strong understanding of the molecular basis for the disease - both nephrologists and nutritionists will benefit Nephrologists and nutritionists will gain insight into which treatments, medications, and diets to use based on the history, progression, and genetic make-up of a patient Case Reports will offer an added resource for fellows, nutritionists, and dieticians who need a refresher course

Calcium and Bone Disorders in Children and Adolescents

Calcium and Bone Disorders in Children and Adolescents
Author: J. Allgrove,N.J. Shaw
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 434
Release: 2015-06-11
ISBN 10: 3318054674
ISBN 13: 9783318054675
Language: EN, FR, DE, ES & NL

Calcium and Bone Disorders in Children and Adolescents Book Review:

There has been a rapid expansion of knowledge in the field of paediatric calcium and bone disorders over the past twenty years. Advances have been made in the underlying genetic basis for many conditions in conjunction with progress in bone density and geometry imaging and the development of new treatment options. The 2nd revised edition of ‘Calcium and Bone Disorders in Children and Adolescents’ presents up-to-date information on many aspects included in the 1st edition such as the physiology, pathology, diagnosis and management of numerous conditions including a chapter of case histories illustrating clinical aspects. New chapters on skeletal dysplasias, the genetics of osteoporosis, radiological imaging of bone and a practical approach to a child with recurrent fractures are included. Providing a comprehensive update, this book is a useful clinical resource for paediatricians and specialists in endocrinology, metabolic bone disease, nephrology, rheumatology, radiology, orthopaedics and clinical genetics who may be faced with a child with a calcium and/or bone disorder.

SP287SERUM FIBROBLAST GROWTH FACTOR 23 FGF 23 SOLUBLE KLOTHO SKLOTHO AND SCLEROSTIN LEVELS AS MARKERS OF CARDIOVASCULAR COMPLICATIONS IN RUSSIAN PATIENTS WITH END STAGE OF RENAL DISEASE REGULAR HEMODIALYSIS AND HEMODIAFILTRATION ON LINE

SP287SERUM FIBROBLAST GROWTH FACTOR 23  FGF 23   SOLUBLE KLOTHO  SKLOTHO  AND SCLEROSTIN LEVELS AS MARKERS OF CARDIOVASCULAR COMPLICATIONS IN RUSSIAN PATIENTS WITH END STAGE OF RENAL DISEASE  REGULAR HEMODIALYSIS AND HEMODIAFILTRATION ON LINE
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 2018
ISBN 10:
ISBN 13: OCLC:1053701733
Language: EN, FR, DE, ES & NL

SP287SERUM FIBROBLAST GROWTH FACTOR 23 FGF 23 SOLUBLE KLOTHO SKLOTHO AND SCLEROSTIN LEVELS AS MARKERS OF CARDIOVASCULAR COMPLICATIONS IN RUSSIAN PATIENTS WITH END STAGE OF RENAL DISEASE REGULAR HEMODIALYSIS AND HEMODIAFILTRATION ON LINE Book Review:

Molecular Genetic and Nutritional Aspects of Major and Trace Minerals

Molecular  Genetic  and Nutritional Aspects of Major and Trace Minerals
Author: James F Collins
Publsiher: Academic Press
Total Pages: 576
Release: 2016-09-14
ISBN 10: 0128023767
ISBN 13: 9780128023761
Language: EN, FR, DE, ES & NL

Molecular Genetic and Nutritional Aspects of Major and Trace Minerals Book Review:

Molecular, Genetic, and Nutritional Aspects of Major and Trace Minerals is a unique reference that provides a complete overview of the non-vitamin micronutrients, including calcium, copper, iodine, iron, magnesium, manganese, molybdenum, phosphorus, potassium, selenium, sodium, and zinc. In addition, the book covers the nutritional and toxicological properties of nonessential minerals chromium, fluoride and boron, and silicon and vanadium, as well as ultra-trace minerals and those with no established dietary requirement for humans. Users will find in-depth chapters on each essential mineral and mineral metabolism, along with discussions of dietary recommendations in the United States and around the world. Presents the only scientific reference to cover all of the nutritionally relevant essential major and trace minerals Provides a broad introductory chapter on each mineral to give readers valuable background and context Clarifies the cellular and molecular aspects of each mineral and its genetic and genomic aspects Includes coverage of all nutritionally relevant minerals—essential major trace minerals and ultra-trace minerals Underscores the important interactions between minerals so readers learn how metabolism of one mineral influences another

Fibroblast Growth Factor 23 and Klotho in Bone mineral and Parathyroid Disorders

Fibroblast Growth Factor 23 and Klotho in Bone mineral and Parathyroid Disorders
Author: Anonim
Publsiher: Unknown
Total Pages: 72
Release: 2009
ISBN 10: 9789155475901
ISBN 13: 9155475906
Language: EN, FR, DE, ES & NL

Fibroblast Growth Factor 23 and Klotho in Bone mineral and Parathyroid Disorders Book Review:

Clinical Aspects of Natural and Added Phosphorus in Foods

Clinical Aspects of Natural and Added Phosphorus in Foods
Author: Orlando M. Gutiérrez,Kamyar Kalantar-Zadeh,Rajnish Mehrotra
Publsiher: Springer
Total Pages: 266
Release: 2017-05-16
ISBN 10: 1493965662
ISBN 13: 9781493965663
Language: EN, FR, DE, ES & NL

Clinical Aspects of Natural and Added Phosphorus in Foods Book Review:

This comprehensive reference covers the impact of dietary phosphorus in phosphorus physiology, public health and the pathogenesis of disease. Divided into three parts, the first section is an overview of the history of phosphorus and the regulation of phosphorus homeostasis. The second section focuses on specific matters related to phosphorus in the food supply. Clinical applications of the material presented in the preceding sections are pulled together in the third section - including the importance of both phosphorus excess and phosphorus deficiency for the pathogenesis of a wide variety of disease including kidney, cardiovascular, bone and oncologic diseases. Clinical Aspects of Natural and Added Phosphorus in Foods is an indispensable resource for understanding the growing importance of dietary phosphorus content in health and disease, enhancing patient care and moving forward the field of phosphorus science.

Chronic Kidney Disease

Chronic Kidney Disease
Author: Thomas Rath
Publsiher: BoD – Books on Demand
Total Pages: 306
Release: 2018-02-21
ISBN 10: 953513843X
ISBN 13: 9789535138433
Language: EN, FR, DE, ES & NL

Chronic Kidney Disease Book Review:

Known worldwide, chronic kidney disease (CKD) is a disease that affects up to 4% of the population with increasing figures also in the developing countries. Life expectancy of patients affected by CKD is shortened compared to the overall population, and only a minority of patients reach end-stage renal disease (ESRD) with the need for dialysis or renal transplantation; death overtakes dialysis. In the 13 chapters, this book sheds light on the different aspects related to pathophysiology and clinical aspects of CKD, providing interesting insights into not only inflammation and cardiovascular risk but also the interplay of hormones and the functional aspects of endothelial function. In addition, chapters dealing with genetic aspects of polycystic kidney disease and also the clinical handling of patients with CKD and peritoneal dialysis will be beneficial for the open-minded reader.

Translational Endocrinology of Bone

Translational Endocrinology of Bone
Author: Gerard Karsenty
Publsiher: Academic Press
Total Pages: 236
Release: 2012-12-31
ISBN 10: 0124158595
ISBN 13: 9780124158597
Language: EN, FR, DE, ES & NL

Translational Endocrinology of Bone Book Review:

The use of model organisms together with the power of genetics has profoundly affected our understanding of the physiology of one organ, the skeleton, in two distinct but complementary ways. This is the first translational reference to focus on these major conceptual advances in bone biology and their development in the clinic. Several advances have already been translated into therapies and others are being tested for diseases as different as osteoporosis, type-2 diabetes, and hypo-fertility. This book is a timely reference for both basic and clinical researchers in bone biology and endocrinology. Summarizes the latest research and translational applications of how the varied growth and development of bone affects appetite, metabolism, reproduction, and a wide range of endocrine functions Provides a common language for bone biologists, endocrinologists, osteologists, and other researchers, such as neuroscientists, who study appetite, fuel metabolism and diabetes, to discuss the development of translational research and new therapeutic strategies for bone, metabolic, and neuro-endocrine diseases. Saves researchers and clinicians time in quickly accessing the very latest details on a broad range of bone research and therapeutics, as opposed to searching through thousands of journal articles

Textbook of Nephro Endocrinology

Textbook of Nephro Endocrinology
Author: Ajay K. Singh,Gordon H. Williams
Publsiher: Academic Press
Total Pages: 522
Release: 2009-01-12
ISBN 10: 9780080920467
ISBN 13: 0080920462
Language: EN, FR, DE, ES & NL

Textbook of Nephro Endocrinology Book Review:

The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology, investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism. Investigates both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems Presents a uniquely comprehensive and cross-disciplinary look at all aspects of nephro-endocrine disorders in one reference work Clear translational presentations by the top endocrinologists and nephrologists in each specific hormone or functional/systems field

Identification of Novel Regulators of Fibroblast Growth Factor 23 FGF23 Production

Identification of Novel Regulators of Fibroblast Growth Factor 23  FGF23  Production
Author: Philipp Glosse
Publsiher: Unknown
Total Pages: 329
Release: 2020*
ISBN 10:
ISBN 13: OCLC:1226671964
Language: EN, FR, DE, ES & NL

Identification of Novel Regulators of Fibroblast Growth Factor 23 FGF23 Production Book Review:

FGF23; Klotho; kidney; calcium; phosphate; Orai1; inflammation; energy deficiency.

Nephrology and Clinical Chemistry The Essential Link

Nephrology and Clinical Chemistry  The Essential Link
Author: Pierre Delanaye
Publsiher: Bentham Science Publishers
Total Pages: 157
Release: 2012-02-13
ISBN 10: 1608053334
ISBN 13: 9781608053339
Language: EN, FR, DE, ES & NL

Nephrology and Clinical Chemistry The Essential Link Book Review:

Clinical chemistry is a science that requires specific knowledge and teaching. The e-book covers several topics in clinical nephrology. Patients suffering from severe chronic kidney disease may be quasi asymptomatic. This lack of overt symptomatology sugg

Bone

Bone
Author: David Scadden
Publsiher: Perspectives Cshl
Total Pages: 232
Release: 2018
ISBN 10: 9781621822202
ISBN 13: 1621822206
Language: EN, FR, DE, ES & NL

Bone Book Review:

Bone plays far more than just a structural role in our bodies. It actively communicates with our brains, kidneys, and other organs, releasing and responding to signaling molecules that regulate biological processes such as glucose metabolism and lymph node development. Defects in these interactions may lead to osteoporosis, multiple myeloma, and other diseases or developmental flaws. Written and edited by experts in the field, this collection from Cold Spring Harbor Perspectives in Medicine examines our current understanding of the dynamic interactions between bone and other organs and systems in the body and the molecules and mechanisms that mediate them. Contributors discuss endocrine factors that act on bone (e.g., parathyroid hormone and sex steroids) as well as molecules that are secreted by bone and act on other tissues (e.g., osteocalcin and FGF23). The interplay between bone and the nervous, immune, and vascular systems is explored, as is the influence of gut microbiota on bone homeostasis. The authors also consider the diseases that result when homeostatic pathways are disrupted and how new knowledge of these pathways may be harnessed for the development of therapeutics. This volume is therefore a valuable reference for not only physiologists and endocrinologists but for all who are interested in diseases linked to the skeletal system.

Vitamin D in Chronic Kidney Disease

Vitamin D in Chronic Kidney Disease
Author: Pablo A. Ureña Torres,Mario Cozzolino,Marc G. Vervloet
Publsiher: Springer
Total Pages: 574
Release: 2016-09-21
ISBN 10: 3319325078
ISBN 13: 9783319325071
Language: EN, FR, DE, ES & NL

Vitamin D in Chronic Kidney Disease Book Review:

Vitamin D deficiency, circulating levels lower than 15 ng/ml, is an epidemic disease worldwide with more than a billion people suffering of it in the beginning of the 21-century. Besides its impact on mineral and bone metabolism, these low vitamin D levels are also associated with a diversity of non-skeletal complications, among them cardiovascular disease, diabetes mellitus, multiple sclerosis, cancer, tuberculosis, and immune system dysfunction. Chronic Kidney Disease is also a very common disease, affecting more than 10% of the world population, ranging from stage 1 to stage 5 before dialysis. Approximately 1% of the population in industrialized countries is affected by end-stage renal disease (ESRD), needing a renal replacement therapy either hemodialysis or peritoneal dialysis, and ultimately by renal transplantation. Those CKD patients are more susceptible to exhibit reduced vitamin D stocks. Consequently, more than eighty percent of CKD patients have either insufficient or deficient vitamin D levels for multiple reasons.

Hormones

Hormones
Author: Anthony W. Norman,Gerald Litwack
Publsiher: Academic Press
Total Pages: 822
Release: 2014-06-28
ISBN 10: 1483258106
ISBN 13: 9781483258102
Language: EN, FR, DE, ES & NL

Hormones Book Review:

Hormones provides a comprehensive treatment of human hormones viewed in the light of modern theories of hormone action and in the context of current understanding of subcellular and cellular architecture and classical organ physiology. The book begins with discussions of the first principles of hormone action and the seven classes of steroid hormones and their chemistry, biosynthesis, and metabolism. These are followed by separate chapters that address either a classical endocrine system, e.g., hypothalamic hormones, posterior pituitary hormones, anterior pituitary hormones, ,thyroid hormones, pancreatic hormones, gastrointestinal hormones, calcium regulating hormones, adrenal corticoids, hormones of the adrenal medulla, androgens, estrogens and progestins, and pregnancy and lactation hormones; or newer domains of hormone action which are essential to a comprehensive understanding of hormone action, including prostaglandins, thymus hormones, and pineal hormones. The book concludes with a presentation of hormones of the future, i.e., cell growth factors. This book is intended for use by first-year medical students, graduate students, and advanced undergraduates in the biological sciences. It is also hoped that this book will fill the void that exists for resource materials for teaching cellular and molecular endocrinology and that it will be employed as an equal partner with most standard biochemistry textbooks to provide a comprehensive and balanced coverage of this realm of biology.

Vitamin D and Rickets

Vitamin D and Rickets
Author: Z. Hochberg
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 291
Release: 2003-01-01
ISBN 10: 3805575823
ISBN 13: 9783805575829
Language: EN, FR, DE, ES & NL

Vitamin D and Rickets Book Review:

Centuries ago, during the industrial revolution, rickets, also called 'the English disease', spread rapidly among city-dwelling poor children and became endemic due to vitamin D deficiency and insufficient access to sunlight. Nowadays it appears to be endemic again as the increase of vitamin D deficiency is paralleling the primacy of breast-feeding in Western societies. Breastfeeding, nutritional status and dark skin are the main risk factors for rickets or 'rachitis' as is the correct medical term. Rickets is a childhood disorder and the basis for understanding the disease is rooted in the concept of mineral metabolism and its control mechanisms in the growing fetus, infant and child. As it is now understood that rickets is not only caused by vitamin D deficiency, it has to be kept in mind that vitamin D and calcium deficiency is prevalent in developing countries as well as in affluent societies, where children and their mothers are not exposed to as much sunlight as they need. The rapid growth in molecular biology has been exemplified in the application of subcellular technologies to study vitamin D in human and animal models. In this volume the latest research on vitamin D and rickets is presented from different perspectives such as the interesting historical overview to bone metabolism, molecular genetics of vitamin D and conclusions for disease prevention. It will be of special interest to pediatricians, endocrinologists and health care specialists who work with children at risk for the disease.