Evolutionary Diversity as a Source for Anticancer Molecules

Evolutionary Diversity as a Source for Anticancer Molecules
Author: Akhileshwar Kumar Srivastava,Vinod Kumar Kannaujiya,Rajesh Kumar Singh,Divya Singh
Publsiher: Academic Press
Total Pages: 390
Release: 2020-09-30
ISBN 10: 0128216980
ISBN 13: 9780128216989
Language: EN, FR, DE, ES & NL

Evolutionary Diversity as a Source for Anticancer Molecules Book Review:

Evolutionary Diversity as a Source for Anticancer Molecules discusses evolutionary diversity as source for anticancer agents derived from bacteria, algae, bryophytes, pteridophytes, and gymnosperms. The book goes over the isolation of anticancer agents and the technologyenabled screening process used to develop anticancer drugs. The book also includes discussion of the nutraceuticals and natural products derived from invertebrates that can be used as part of cancer treatment. Evolutionary Diversity as a Source for Anticancer Molecules also deals with some of the current challenges in the prevention of cancer as well as the side effects of conventional drugs used for cancer patients. This book is a valuable resource for cancer researchers, oncologists, biotechnologists, pharmacologists, and any member of the biomedical field interested in understanding more about natural products with anticancer potential. Discusses the application of natural products in place of conventional drugs to minimize the side effects in cancer treatment Explains the relation between evolutionary mechanisms and climate change for production of secondary metabolites

Nutrition Food and Diet in Ageing and Longevity

Nutrition  Food and Diet in Ageing and Longevity
Author: Suresh I. S. Rattan,Gurcharan Kaur
Publsiher: Springer Nature
Total Pages: 642
Release: 2021-11-04
ISBN 10: 3030830179
ISBN 13: 9783030830175
Language: EN, FR, DE, ES & NL

Nutrition Food and Diet in Ageing and Longevity Book Review:

This edited volume is a compilation of 30 articles discussing what constitutes food for health and longevity. The aim is to provide up-to-date information, insights, and future tendencies in the ongoing scientific research about nutritional components, food habits and dietary patterns in different cultures. The health-sustaining and health-promoting effects of food are certainly founded in its overall composition of macronutrients and micronutrients. However, the consumption of these nutrients is normally in the form of raw or prepared food from the animal and plant sources. The book is divided into four parts and a conclusion, and successfully convenes the well-established information and knowledge, along with the personal views of a diversified group of researchers and academicians on the multifaceted aspects of nutrition, food and diet. The first part reviews the scientific information about proteins, carbohydrates, fats and oils, micronutrients, pro- and pre-biotics, and hormetins, along with a discussion of the evolutionary principles and constraints about what is optimal food, if any. The second part discusses various kinds of foods and food supplements with respect to their claimed benefits for general health and prevention of some diseases. The third part brings in the cultural aspects, such as what are the principles of healthy eating according to the traditional Chinese and Indian systems, what is the importance of mealing times and daily rhythms, and how different cultures have developed different folk wisdoms for eating for health, longevity and immortality. In the part four, various approaches which are either already in practice or are still in the testing and research phases are discussed and evaluated critically, for example intermittent fasting and calorie restriction, food-based short peptides, senolytics, Ayurvedic compounds, optimal food for old people, and food for the prevention of obesity and other metabolic disorders. The overreaching aim of this book is to inform, inspire and encourage students, researchers, educators and medical health professionals thinking about food and food habits in a holistic context of our habits, cultures and patterns. Food cannot be reduced to a pill of nutritional components. Eating food is a complex human behavior culturally evolved over thousands of years. Perhaps the old adage “we are what we eat” needs to be modified to “we eat what we are”.

Natural Products and Cancer Drug Discovery

Natural Products and Cancer Drug Discovery
Author: Farid A. Badria
Publsiher: BoD – Books on Demand
Total Pages: 316
Release: 2017-07-05
ISBN 10: 9535133136
ISBN 13: 9789535133131
Language: EN, FR, DE, ES & NL

Natural Products and Cancer Drug Discovery Book Review:

This book, Natural Products and Cancer Drug Discovery, is written by leading experts in natural products in cancer therapy. The first two sections describe new applications of common herbs and foods for treatment of cancer. Section 3 deals with the development of new chemotherapeutics from Cannabis and endophytic fungi. Section 4 presented formulations of natural products for treatment of malignant melanoma. Made-to-order anticancer therapy from natural products using computational and tissue engineering approaches is addressed in the fifth section. It is our hope that this book may motivate readers to approach the evidence of anticancer natural products with an open mind and thereby spark an interest in making further contributions to the cancer treatment efforts.

Biotechnology and Production of Anti Cancer Compounds

Biotechnology and Production of Anti Cancer Compounds
Author: Sonia Malik
Publsiher: Springer
Total Pages: 328
Release: 2017-04-21
ISBN 10: 3319538802
ISBN 13: 9783319538808
Language: EN, FR, DE, ES & NL

Biotechnology and Production of Anti Cancer Compounds Book Review:

This book discusses cancers and the resurgence of public interest in plant-based and herbal drugs. It also describes ways of obtaining anti-cancer drugs from plants and improving their production using biotechnological techniques. It presents methods such as cell culture, shoot and root culture, hairy root culture, purification of plant raw materials, genetic engineering, optimization of culture conditions as well as metabolic engineering with examples of successes like taxol, shikonin, ingenol mebutate and podophylotoxin. In addition, it describes the applications and limitations of large-scale production of anti-cancer compounds using biotechnological means. Lastly, it discusses future economical and eco-friendly strategies for obtaining anti-cancer compounds using biotechnology.

From Monsoons to Microbes

From Monsoons to Microbes
Author: National Research Council,Commission on Geosciences, Environment and Resources,Ocean Studies Board,Committee on the Ocean's Role in Human Health
Publsiher: National Academies Press
Total Pages: 144
Release: 1999-05-05
ISBN 10: 9780309173421
ISBN 13: 0309173426
Language: EN, FR, DE, ES & NL

From Monsoons to Microbes Book Review:

What can sharks teach us about our immune system? What can horseshoe crabs show us about eyesight? The more we learn about the ocean, the more we realize how critical these vast bodies of water are to our health and well-being. Sometimes the ocean helps us, as when a marine organism yields a new medical treatment. At other times, the ocean poses the threat of coastal storm surges or toxic algal blooms. From Monsoons to Microbes offers a deeper look into the oceans that surround us, often nurturing yet sometimes harming humankind. This book explores the links among physical oceanography, public health, epidemiology, marine biology, and medicine in understanding what the ocean has to offer. It will help readers grasp such important points as: How the ocean's sweeping physical processes create long-term phenomena such as El Nino and short-term disastrous events such as tsunamis--including what communities can do to prepare. What medicines and nutritional products have come from the ocean and what the prospects are for more such discoveries. How estuaries work--where salt and fresh water meet--and what can go wrong, as in the 7,000 square mile "dead zone" at the out-flow of the Mississippi River. How the growing demand for seafood and the expansion of ocean-going transport has increased our exposure to infectious agents--and how these agents can be tracked down and fought. Why "red tides" of toxic algae suddenly appear in previously unaffected coastal areas, and what happens when algal toxins find their way into our food supply or the air we breathe. The book recommends ways we can implement exciting new technologies to monitor the physics, chemistry, and biology of the ocean to recognize change as it happens. From the impact of worldwide atmospheric warming to the significance of exotic bacteria from submarine hydrothermal vents, the ocean has many depths left to explore.

Chemistry and Pharmacology of Anticancer Drugs

Chemistry and Pharmacology of Anticancer Drugs
Author: David E. Thurston,Ilona Pysz
Publsiher: CRC Press
Total Pages: 618
Release: 2021-03-17
ISBN 10: 1439853274
ISBN 13: 9781439853276
Language: EN, FR, DE, ES & NL

Chemistry and Pharmacology of Anticancer Drugs Book Review:

While drug therapies developed in the last 80 years have markedly improved treatment outcomes and the management of some types of cancers, the lack of effectiveness and side effects associated with the most common treatment types remain unacceptable. However, recent technological advances are leading to improved therapies based on targeting distinct biological pathways in cancer cells. Chemistry and Pharmacology of Anticancer Drugs is a comprehensive survey of all families of anticancer agents and therapeutic approaches currently in use or in advanced stages of clinical trials, including biological-based therapies. The book is unique in providing molecular structures for all anticancer agents, discussing them in terms of history of development, chemistry, mechanism of action, structure–function relationships, and pharmacology. It also provides relevant information on side effects, dosing, and formulation. The authors, renowned scientists in cancer research and drug discovery, also provide up-to-date information on the drug discovery process, including discussions of new research tools, tumor-targeting strategies, and fundamental concepts in the relatively new areas of precision medicine and chemoprevention. Chemistry and Pharmacology of Anticancer Drugs is an indispensable resource for cancer researchers, medicinal chemists and other biomedical scientists involved in the development of new anticancer therapies. Its breadth of coverage, clear explanations, and illustrations also make it suitable for undergraduate and postgraduate courses in medicine, pharmacy, nursing, dentistry, nutrition, the biomedical sciences, and related disciplines. Key Features: Summarizes the fundamental causes of cancer, modes of treatment, and strategies for cancer drug discovery Brings together a broad spectrum of information relating to the chemistry and pharmacology of all families of anticancer agents and therapies Includes up-to-date information on cutting-edge aspects of cancer treatments such as biomarkers, pharmacogenetics, and pharmacogenomics Features new chapters on the "Evolution of Anticancer Therapies", "Antibody-Based Therapies", and "Cancer Chemoprevention"

New and Future Developments in Microbial Biotechnology and Bioengineering

New and Future Developments in Microbial Biotechnology and Bioengineering
Author: Vijai G. Gupta,Anita Pandey
Publsiher: Elsevier
Total Pages: 380
Release: 2019-06-14
ISBN 10: 0444635114
ISBN 13: 9780444635112
Language: EN, FR, DE, ES & NL

New and Future Developments in Microbial Biotechnology and Bioengineering Book Review:

New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered. The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community. Compiles the latest developments in the area of microbial secondary metabolites Authored by the top international researchers in this area Includes information related to nearly all areas of a microbial secondary metabolites system

Medicinal Chemistry

Medicinal Chemistry
Author: Thomas Nogrady,Donald F. Weaver
Publsiher: Oxford University Press
Total Pages: 649
Release: 2005-08-11
ISBN 10: 0190282967
ISBN 13: 9780190282967
Language: EN, FR, DE, ES & NL

Medicinal Chemistry Book Review:

Fully updated and rewritten by a basic scientist who is also a practicing physician, the third edition of this popular textbook remains comprehensive, authoritative and readable. Taking a receptor-based, target-centered approach, it presents the concepts central to the study of drug action in a logical, mechanistic way grounded on molecular and principles. Students of pharmacy, chemistry and pharmacology, as well as researchers interested in a better understanding of drug design, will find this book an invaluable resource. Starting with an overview of basic principles, Medicinal Chemistry examines the properties of drug molecules, the characteristics of drug receptors, and the nature of drug-receptor interactions. Then it systematically examines the various families of receptors involved in human disease and drug design. The first three classes of receptors are related to endogenous molecules: neurotransmitters, hormones and immunomodulators. Next, receptors associated with cellular organelles (mitochondria, cell nucleus), endogenous macromolecules (membrane proteins, cytoplasmic enzymes) and pathogens (viruses, bacteria) are examined. Through this evaluation of receptors, all the main types of human disease and all major categories of drugs are considered. There have been many changes in the third edition, including a new chapter on the immune system. Because of their increasingly prominent role in drug discovery, molecular modeling techniques, high throughput screening, neuropharmacology and genetics/genomics are given much more attention. The chapter on hormonal therapies has been thoroughly updated and re-organized. Emerging enzyme targets in drug design (e.g. kinases, caspases) are discussed, and recent information on voltage-gated and ligand-gated ion channels has been incorporated. The sections on antihypertensive, antiviral, antibacterial, anti-inflammatory, antiarrhythmic, and anticancer drugs, as well as treatments for hyperlipidemia and peptic ulcer, have been substantially expanded. One new feature will enhance the book's appeal to all readers: clinical-molecular interface sections that facilitate understanding of the treatment of human disease at a molecular level.

Secondary Metabolites

Secondary Metabolites
Author: Ramasamy Vijayakumar,Suresh S.S. Raja
Publsiher: BoD – Books on Demand
Total Pages: 148
Release: 2018-09-05
ISBN 10: 1789236428
ISBN 13: 9781789236422
Language: EN, FR, DE, ES & NL

Secondary Metabolites Book Review:

This book consists of an introductory overview of secondary metabolites, which are classified into four main sections: microbial secondary metabolites, plant secondary metabolites, secondary metabolites through tissue culture technique, and regulation of secondary metabolite production. This book provides a comprehensive account on the secondary metabolites of microorganisms, plants, and the production of secondary metabolites through biotechnological approach like the plant tissue culture method. The regulatory mechanisms of secondary metabolite production in plants and the pharmaceutical and other applications of various secondary metabolites are also highlighted. This book is considered as necessary reading for microbiologists, biotechnologists, biochemists, pharmacologists, and botanists who are doing research in secondary metabolites. It should also be useful to MSc students, MPhil and PhD scholars, scientists, and faculty members of various science disciplines.

Flavonoids

Flavonoids
Author: José Justino
Publsiher: BoD – Books on Demand
Total Pages: 484
Release: 2017-08-23
ISBN 10: 953513423X
ISBN 13: 9789535134237
Language: EN, FR, DE, ES & NL

Flavonoids Book Review:

Flavonoids are abundant secondary metabolites found in plants and fungi that have various roles in these organisms, including pigmentation, cell signalling, plant defence and inter-organism communication. Due to their abundance in nature, flavonoids are also important components of the human diet, and the last four decades have seen an intense study focused on the structure characterization of flavonoids and on their roles in mammal metabolism. This book reviews most of the well-established activities of flavonoids, and we also present more recent research studies on the area of flavonoids, including the chemical aspects of structure characterization of flavonoids, the biosynthesis of flavonoids in model plants as well as their role in abiotic stress situations and in agriculture, the role of flavonoids in metabolism and health and their importance in foods, from consumption to their use as bioactive components.

Anticancer Drug Development

Anticancer Drug Development
Author: Bruce C. Baguley,David J. Kerr
Publsiher: Elsevier
Total Pages: 397
Release: 2001-11-17
ISBN 10: 0080490441
ISBN 13: 9780080490441
Language: EN, FR, DE, ES & NL

Anticancer Drug Development Book Review:

Here in a single source is a complete spectrum of ideas on the development of new anticancer drugs. Containing concise reviews of multidisciplinary fields of research, this book offers a wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death. Detailed descriptions of sources for new drugs and methods for testing and clinical trial design are also provided. One work that can be consulted for all aspects of anticancer drug development Concise reviews of research fields, combined with practical scientific detail, written by internationally respected experts A wealth of ideas on current and future molecular targets for drug design, including signal transduction, the cell division cycle, and programmed cell death Detailed descriptions of the sources of new anticancer drugs, including combinatorial chemistry, phage display, and natural products Discussion of how new drugs can be tested in preclinical systems, including the latest technology of robotic assay systems, cell culture, and experimental animal techniques Hundreds of references that allow the reader to access relevant scientific and medical literature Clear illustrations, some in color, that provide both understanding of the field and material for teaching

Biological Diversity and Sustainable Resources Use

Biological Diversity and Sustainable Resources Use
Author: Oscar Grillo,Gianfranco Venora
Publsiher: BoD – Books on Demand
Total Pages: 168
Release: 2011-11-14
ISBN 10: 9533077069
ISBN 13: 9789533077062
Language: EN, FR, DE, ES & NL

Biological Diversity and Sustainable Resources Use Book Review:

Biological Diversity and Sustainable Resources Use is a very interesting volume, including attractive overviews and original case studies mainly focused on socio-economical effects of the right management of the ecosystems biodiversity, as well as on the useful integration between human activities and environmental responses. Ecological, medical and historical aspects of the sustainable development are also discussed in this book which consists of articles written by international experts, offering the reader a clear and extensive view of the present condition in which our planet is.

Globalization Biosecurity and the Future of the Life Sciences

Globalization  Biosecurity  and the Future of the Life Sciences
Author: National Research Council,Institute of Medicine,Board on Global Health,Policy and Global Affairs,Development, Security, and Cooperation,Committee on Advances in Technology and the Prevention of Their Application to Next Generation Biowarfare Threats
Publsiher: National Academies Press
Total Pages: 316
Release: 2006-06-07
ISBN 10: 9780309164757
ISBN 13: 0309164753
Language: EN, FR, DE, ES & NL

Globalization Biosecurity and the Future of the Life Sciences Book Review:

Biomedical advances have made it possible to identify and manipulate features of living organisms in useful ways--leading to improvements in public health, agriculture, and other areas. The globalization of scientific and technical expertise also means that many scientists and other individuals around the world are generating breakthroughs in the life sciences and related technologies. The risks posed by bioterrorism and the proliferation of biological weapons capabilities have increased concern about how the rapid advances in genetic engineering and biotechnology could enable the production of biological weapons with unique and unpredictable characteristics. Globalization, Biosecurity, and the Future of Life Sciences examines current trends and future objectives of research in public health, life sciences, and biomedical science that contain applications relevant to developments in biological weapons 5 to 10 years into the future and ways to anticipate, identify, and mitigate these dangers.

Phytochemicals

Phytochemicals
Author: Toshiki Asao,Md Asaduzzaman
Publsiher: BoD – Books on Demand
Total Pages: 218
Release: 2018-11-07
ISBN 10: 1789843774
ISBN 13: 9781789843774
Language: EN, FR, DE, ES & NL

Phytochemicals Book Review:

Phytochemicals provides original research work and reviews on the sources of phytochemicals, and their roles in disease prevention, supplementation, and accumulation in fruits and vegetables. The roles of anthocyanin, flavonoids, carotenoids, and taxol are presented in separate chapters. Antioxidative and free radicle scavenging activity of phytochemicals is also discussed. The medicinal properties of Opuntia, soybean, sea buckthorn, and gooseberry are presented in a number of chapters. Supplementation of plant extract with phytochemical properties in broiler meals is discussed in one chapter. The final two chapters include the impact of agricultural practices and novel processing technologies on the accumulation of phytochemicals in fruits and vegetables. This book mainly focuses on medicinal plants and the disease-preventing properties of phytochemicals, which will be a useful resource to the reader.

Bioactive Compounds from Natural Sources

Bioactive Compounds from Natural Sources
Author: Corrado Tringali
Publsiher: CRC Press
Total Pages: 648
Release: 2011-09-27
ISBN 10: 1439870667
ISBN 13: 9781439870662
Language: EN, FR, DE, ES & NL

Bioactive Compounds from Natural Sources Book Review:

The first edition of Bioactive Compounds from Natural Sources was published in a period of renewed attention to biologically active compounds of natural origin. This trend has continued and intensified-natural products are again under the spotlight, in particular for their possible pharmacological applications. Largely focusing on natural products

Apoptosis and Development

Apoptosis and Development
Author: Anonim
Publsiher: Academic Press
Total Pages: 388
Release: 2015-10-05
ISBN 10: 0124095984
ISBN 13: 9780124095984
Language: EN, FR, DE, ES & NL

Apoptosis and Development Book Review:

Apoptosis and Development, the latest volume of Current Topics in Developmental Biology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in apoptosis and development, and includes sections on such topics as the non-lethal role of apoptotic proteins and germ line cell death in Drosophila. Continues the legacy of this premier serial with quality chapters authored by leaders in the field Includes descriptions of the most recent advances in the field Covers research methods in apoptosis and development, and includes sections on such topics as the non-lethal role of apoptotic proteins and germ line cell death in Drosophila

Viral Proteases and Their Inhibitors

Viral Proteases and Their Inhibitors
Author: Satya Prakash Gupta
Publsiher: Academic Press
Total Pages: 516
Release: 2017-07-03
ISBN 10: 0128096829
ISBN 13: 9780128096826
Language: EN, FR, DE, ES & NL

Viral Proteases and Their Inhibitors Book Review:

Viral Proteases and Their Inhibitors provides a thorough examination of viral proteases from their molecular components, to therapeutic applications. As information on three dimensional structures and biological functions of these viral proteases become known, unexpected protein folds and unique mechanisms of proteolysis are realized. This book investigates how this facilitates the design and development of potent antiviral agents used against life-threatening viruses. Users will find descriptions of each virus that detail the structure and function of viral proteases, discuss the design and development of inhibitors, and analyze the structure-activity relationships of inhibitors. This book is ideal biochemists, virologists and those working on antiviral agents. Provides comprehensive, state-of-the-art coverage of virus infections, the virus lifecycle, and mechanisms of protease inhibition Analyzes structure-activity relationships of inhibitors of each viral protease Presents an in-depth view of the structure and function of viral proteases

Molecular Diversity of Environmental Prokaryotes

Molecular Diversity of Environmental Prokaryotes
Author: Thiago Bruce Rodrigues,Amaro Emiliano Trindade Silva
Publsiher: CRC Press
Total Pages: 379
Release: 2016-08-19
ISBN 10: 1482233231
ISBN 13: 9781482233230
Language: EN, FR, DE, ES & NL

Molecular Diversity of Environmental Prokaryotes Book Review:

This book correlates the vast genetic diversity associated with environmental samples and still underexploited potential for the development of biotechnology products. The book points out the potential of different types of environmental samples. It presents the main characteristics of microbial diversity, the main approaches used for molecular characterization of the diversity, and practical examples of application of the exploration of the microbial diversity. It presents a not-yet-explored structure for discussing the main topics related to molecular biology of environmental prokaryotes and their biotechnological applications.

Plant Based Green Chemistry 2 0

Plant Based    Green Chemistry 2 0
Author: Ying Li,Farid Chemat
Publsiher: Springer
Total Pages: 375
Release: 2019-07-08
ISBN 10: 9811338108
ISBN 13: 9789811338106
Language: EN, FR, DE, ES & NL

Plant Based Green Chemistry 2 0 Book Review:

This book provides practical information on obtaining and using a wide variety of plant based reagents for different sectors, addressing the needs and challenges in a single resource. The chapters complement each other seamlessly and present contributions from reputed international researchers and renowned professionals from industry, covering the latest efforts in the field. The book serves as the starting point for future collaborations in the new area “Plant Based Green Chemistry” between research, industry, and education, covering large ecologic and economic applications: perfume, cosmetic, pharmaceutical, food ingredients, nutraceuticals, biofuels, or fine chemicals industries. This book is aimed at professionals from industries, academicians engaged in plant based green chemistry, researchers and graduate level students, but will also be useful to food technologists and students and researchers involved in natural products chemistry.

Understanding Cancer Therapies

Understanding Cancer Therapies
Author: Prakash Srinivasan Timiri Shanmugam
Publsiher: CRC Press
Total Pages: 174
Release: 2018-03-09
ISBN 10: 1351982958
ISBN 13: 9781351982955
Language: EN, FR, DE, ES & NL

Understanding Cancer Therapies Book Review:

This book is an introduction to cancer treatment, the basics of radio- and chemotherapy, drug actions, the eradication of cancer cells, and the origins and persistence of pharmacological and toxicological effects of drugs. It further provides ideas for research based on knowledge of cancer metastasis, invasive and molecular pathways, and diagnosis and treatment. Many of the adaptive features of cancer biology, clinical features, pathology and treatment are reviewed. In addition to introducing the major themes and theories, the book also advances the current discussion by moving beyond explanations for clinical implementation. Key Selling Features: Reviews basic cancer treatments Summarizes chemotherapies Discusses radiotherapies Examines pharmacological and toxicological approaches to treatment Introduces oncological drug development