Epigenetics and Reproductive Health

Epigenetics and Reproductive Health
Author: Anonim
Publsiher: Academic Press
Total Pages: 444
Release: 2020-09-12
ISBN 10: 0128197544
ISBN 13: 9780128197547
Language: EN, FR, DE, ES & NL

Epigenetics and Reproductive Health Book Review:

Epigenetics and Reproductive Health, a new volume in the Translational Epigenetics series, provides a thorough overview and discussion of epigenetics in reproduction and implications for reproductive medicine. Twenty international researchers discuss epigenetic mechanisms operating during the formation of male and female gametes, fertilization and subsequent embryo and placental development, particularly in mammals and transgenerational epigenetic inheritance. This volume also addresses aberrant epigenetic changes influencing male and female infertility, pregnancy related disorders, and those potentially linked to therapeutic manipulations and assisted reproductive technologies. Emphasis is placed on identifying biomarkers for early detection of aberrant epigenetic mechanisms. Later chapters examine the possibility of correcting these epigenetic dysfunctions, as well as current challenges and next steps in research, enabling new translational discoveries and efforts towards developing therapeutics. Thoroughly examines the influence of aberrant epigenetics during gametogenesis and embryogenesis, affecting parents, gametes and embryos, offspring and future generations Explores health outcomes for reproductive senescence, endocrine disruption, testicular cancer, prostrate cancer, breast cancer, ovarian, cancer, endometrial cancer and cervical cancers Features chapter contributions from international researchers in the field

Epigenetics and Assisted Reproduction

Epigenetics and Assisted Reproduction
Author: Cristina Camprubí,Joan Blanco
Publsiher: CRC Press
Total Pages: 202
Release: 2018-08-16
ISBN 10: 1351804448
ISBN 13: 9781351804448
Language: EN, FR, DE, ES & NL

Epigenetics and Assisted Reproduction Book Review:

Epigenetics is the study of how certain genes are activated without modification at the DNA sequence level, resulting in genetically similar individuals having different clinical outcomes. As contemporary medicine increasingly aims to personalize the medical approach to a patient's genetic profile, the factors that can affect which genes are expressed also increase in importance and relevance to the clinician. This text from experts will give the clinician in Reproductive Medicine a reliable grounding in current thinking and research on this fast-moving topic, with many clinical implications.

Human Reproductive Genetics

Human Reproductive Genetics
Author: Juan A. Garcia-Velasco,Emre Seli
Publsiher: Academic Press
Total Pages: 340
Release: 2020-04-19
ISBN 10: 0128167491
ISBN 13: 9780128167496
Language: EN, FR, DE, ES & NL

Human Reproductive Genetics Book Review:

Human Reproductive Genetics: Emerging Technologies and Clinical Applications presents a great reference for clinicians and researchers in reproductive medicine. Part I includes a brief background of genetics and epigenetics, probability of disease, and the different techniques that are being used today for analysis and genetic counseling. Part II focuses on the analysis of the embryo, current controversies and future concepts. Part III comprises different clinical scenarios that clinicians frequently face in practice. The increasing amount of genetic tests available and the growing information that patients handle makes this section a relevant part of the fertility treatment discussion. Finally, Part IV concludes with the psychological aspects of genetic counseling and the role of counselor and bioethics in human reproduction. Provides an essential reference for clinicians involved in reproductive medicine Builds foundational knowledge on new genetic tests coming into the clinical scenario for physicians involved with patients Assembles critically evaluated chapters that cover basic concepts of genetics and epigenetics and the techniques involved, including preimplantation genetic testing, controversies, and more

Textbook of Human Reproductive Genetics

Textbook of Human Reproductive Genetics
Author: Karen Sermon,Stéphane Viville
Publsiher: Cambridge University Press
Total Pages: 200
Release: 2014-04-10
ISBN 10: 1107683580
ISBN 13: 9781107683587
Language: EN, FR, DE, ES & NL

Textbook of Human Reproductive Genetics Book Review:

This book brings together genetics, reproductive biology and medicine for an integrative view of the emerging specialism of reproductive genetics.

The Epigenetics Revolution

The Epigenetics Revolution
Author: Nessa Carey
Publsiher: Columbia University Press
Total Pages: 352
Release: 2012-03-06
ISBN 10: 0231530714
ISBN 13: 9780231530712
Language: EN, FR, DE, ES & NL

The Epigenetics Revolution Book Review:

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

The Epigenome and Developmental Origins of Health and Disease

The Epigenome and Developmental Origins of Health and Disease
Author: Cheryl S Rosenfeld
Publsiher: Academic Press
Total Pages: 560
Release: 2015-10-10
ISBN 10: 0128016728
ISBN 13: 9780128016725
Language: EN, FR, DE, ES & NL

The Epigenome and Developmental Origins of Health and Disease Book Review:

The Epigenome and Developmental Origins of Health and Disease synthesizes the existing knowledge on how the in utero environment could be the most important environment in shaping later risk for various diseases or to conversely promote the health of the offspring. The book mines the existing literature from a variety of disciplines from toxicology to nutrition to epigenetics to reveal how contrasting maternal in utero environmental changes might be leading to epigenetic convergence and the resulting deleterious phenotypic and physiological effects in our offspring. It is increasingly becoming apparent that even subtle changes in the mother’s diet, stress, and exposure to low concentrations of toxic chemicals at levels deemed safe by the EPA and FDA, such as endocrine disrupting compounds (EDC), can dramatically impact the health of our children, possibly leading to metabolic, cardiovascular, immunological, neurobehavioral disorders, and increased risk for cancer to list but a few examples. Informs how everyday choices pregnant women make can impact child development Ties together how in utero environmental changes may be inducing epigenetic changes in the offspring leading to overlapping phenotypes regardless of the initial insult (toxic, nutrition, or stress) Includes a boxed-in area in each chapter for further references and resources to keep up with the field Features video interviews with the authors and other key leaders in the field

Reproductomics

Reproductomics
Author: José A. Horcajadas,Jaime Gosálvez
Publsiher: Academic Press
Total Pages: 425
Release: 2018-07-23
ISBN 10: 0128126760
ISBN 13: 9780128126769
Language: EN, FR, DE, ES & NL

Reproductomics Book Review:

Recent advances in genomic and omics analysis have triggered a revolution affecting nearly every field of medicine, including reproductive medicine, obstetrics, gynecology, andrology, and infertility treatment. Reproductomics: The –Omics Revolution and Its Impact on Human Reproductive Medicine demonstrates how various omics technologies are already aiding fertility specialists and clinicians in characterizing patients, counseling couples towards pregnancy success, informing embryo selection, and supporting many other positive outcomes. A diverse range of chapters from international experts examine the complex relationship between genomics, transcriptomics, proteomics, and metabolomics and their role in human reproduction, identifying molecular factors of clinical significance. With this book Editors Jaime Gosálvez and José A. Horcajadas have provided researchers and clinicians with a strong foundation for a new era of personalized reproductive medicine. Thoroughly discusses how genomics and other omics approaches aid clinicians in various areas of reproductive medicine Identifies specific genomic and molecular factors of translational value in treating infertility and analyzing patient data Features chapter contributions by leading international experts

Epigenetics In Human Reproduction And Development

Epigenetics In Human Reproduction And Development
Author: Naumova Anna K,Taketo-hosotani Teruko
Publsiher: World Scientific
Total Pages: 304
Release: 2016-12-20
ISBN 10: 9813144289
ISBN 13: 9789813144286
Language: EN, FR, DE, ES & NL

Epigenetics In Human Reproduction And Development Book Review:

Epigenetics is defined as heritable changes that do not affect the DNA sequence but influence gene expression. Epigenetic changes occur at the levels of DNA, histone, protein, and chromatin structures. Proper epigenetic modifications are essential for cell differentiation and function during development, while some epigenetic modifications are passed on from parents to offspring through gametes. Therefore, alterations of epigenetic states would have serious consequences for human development and health. This realization and the advent of new technologies have encouraged the advance of epigenetic studies in recent years. Nonetheless, many aspects of epigenetics, such as regulatory mechanisms and evolutional advantages, remain to be better understood. Written by 26 scientists at the forefront of epigenetics research, this book discusses the different facets of epigenetics: from gametogenesis to child development, as well as from mechanistic studies in animal models to reviews of human clinical data.

Medical Epigenetics

Medical Epigenetics
Author: Trygve Tollefsbol
Publsiher: Academic Press
Total Pages: 924
Release: 2016-06-21
ISBN 10: 0128032405
ISBN 13: 9780128032404
Language: EN, FR, DE, ES & NL

Medical Epigenetics Book Review:

Medical Epigenetics provides a comprehensive analysis of the importance of epigenetics to health management. The purpose of this book is to fill a current need for a comprehensive volume on the medical aspects of epigenetics with a focus on human systems, epigenetic diseases that affect these systems and modes of treating epigenetic-based disorders and diseases. The intent of this book is to provide a stand-alone comprehensive volume that will cover all human systems relevant to epigenetic maladies and all major aspects of medical epigenetics. The overall goal is to provide the leading book on medical epigenetics that will be useful not only to physicians, nurses, medical students and many others directly involved with health care, but also investigators in life sciences, biotech companies, graduate students and many others who are interested in more applied aspects of epigenetics. Research in the area of translational epigenetics is a cornerstone of this volume. Critical reviews dedicated to the burgeoning role of epigenetics in medical practice Coverage of emerging topics including twin epigenetics as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Encompasses a disease-oriented perspective of medical epigenetics as well as diagnostic and prognostic epigenetic approaches to applied medicine

Environmental Epigenetics

Environmental Epigenetics
Author: L. Joseph Su,Tung-chin Chiang
Publsiher: Springer
Total Pages: 321
Release: 2015-05-18
ISBN 10: 1447166787
ISBN 13: 9781447166788
Language: EN, FR, DE, ES & NL

Environmental Epigenetics Book Review:

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Transgenerational Epigenetics

Transgenerational Epigenetics
Author: Trygve Tollefsbol
Publsiher: Elsevier
Total Pages: 412
Release: 2014-05-02
ISBN 10: 0124059228
ISBN 13: 9780124059221
Language: EN, FR, DE, ES & NL

Transgenerational Epigenetics Book Review:

Transgenerational Epigenetics provides a comprehensive analysis of the inheritance of epigenetic phenomena between generations. Recent research points to the existence of biological phenomena that are controlled not through gene mutations, but rather through reversible and heritable epigenetic processes. Epidemiological studies have suggested that environmental factors may be heritable. In fact, environmental factors often play a role in transgenerational epigenetics, which may have selective or adverse effects on the offspring. This epigenetic information can be transferred through a number of mechanisms including DNA methylation, histone modifications or RNA and the effects can persist for multiple generations. This book examines the evolution of epigenetic inheritance, its expression in animal and plant models, and how human diseases, such as metabolic disorders and cardiovascular diseases, appear to be affected by transgenerational epigenetic inheritance. It discusses clinical interventions in transgenerational epigenetic inheritance that may be on the horizon to help prevent diseases before the offspring are born, or to reduce the severity of diseases at the very earliest stages of development in utero, and current controversies in this area of study, as well as future directions for research. Focused discussion of metabolic disorders, cardiovascular diseases and longevity, which appear most affected by reversible and heritable epigenetic processes Encompasses both foundational and clinical aspects including discussions of preventative in utero therapies Covers history, future outlook, disease management and current controversies

Epigenetics in Human Disease

Epigenetics in Human Disease
Author: Trygve O. Tollefsbol
Publsiher: Academic Press
Total Pages: 577
Release: 2012
ISBN 10: 0123884152
ISBN 13: 9780123884152
Language: EN, FR, DE, ES & NL

Epigenetics in Human Disease Book Review:

Epigenetics is one of the fastest growing fields of sciences, illuminating studies of human diseases by looking beyond genetic make-up and acknowledging that outside factors play a role in gene expression. The goal of this volume is to highlight those diseases or conditions for which we have advanced knowledge of epigenetic factors such as cancer, autoimmune disorders and aging as well as those that are yielding exciting breakthroughs in epigenetics such as diabetes, neurobiological disorders and cardiovascular disease. Where applicable, attempts are made to not only detail the role of epigenetics in the etiology, progression, diagnosis and prognosis of these diseases, but also novel epigenetic approaches to the treatment of these diseases. Chapters are also presented on human imprinting disorders, respiratory diseases, infectious diseases and gynecological and reproductive diseases. Since epigenetics plays a major role in the aging process, advances in the epigenetics of aging are highly relevant to many age-related human diseases. Therefore, this volume closes with chapters on aging epigenetics and breakthroughs that have been made to delay the aging process through epigenetic approaches. With its translational focus, this book will serve as valuable reference for both basic scientists and clinicians alike. Comprehensive coverage of fundamental and emergent science and clinical usage Side-by-side coverage of the basis of epigenetic diseases and their treatments Evaluation of recent epigenetic clinical breakthroughs

Human Reproductive and Prenatal Genetics

Human Reproductive and Prenatal Genetics
Author: Peter C. K. Leung,Jie Qiao
Publsiher: Academic Press
Total Pages: 709
Release: 2018-08-28
ISBN 10: 0128135719
ISBN 13: 9780128135716
Language: EN, FR, DE, ES & NL

Human Reproductive and Prenatal Genetics Book Review:

Human Reproductive and Prenatal Genetics presents the latest material from a detailed molecular, cellular and translational perspective. Considering its timeliness and potential international impact, this all-inclusive and authoritative work is ideal for researchers, students, and clinicians worldwide. Currently, there are no comprehensive books covering the field of human reproductive and prenatal genetics. As such, this book aims to be among the largest and most useful references available. Features chapter contributions from leading international scientists and clinicians Provides in-depth coverage of key topics in human reproductive and prenatal genetics, including genetic controls, fertilization and implantation, in vitro culture of the human embryo for the study of post-implantation development, and more Identifies how researchers and clinicians can implement the latest genetic, epigenetic, and –omics based approaches

Epigenetics and Human Health

Epigenetics and Human Health
Author: Alexander Haslberger,Sabine Greßler
Publsiher: John Wiley & Sons
Total Pages: 316
Release: 2011-08-24
ISBN 10: 352764475X
ISBN 13: 9783527644759
Language: EN, FR, DE, ES & NL

Epigenetics and Human Health Book Review:

After first introducing the concept of epigenetics, this handbook and ready reference provides an overview of the main research on epigenetics. It adopts a multidisciplinary approach, involving molecular biology, molecular epidemiology and nutritional science, with a special focus of the book is on disease prevention and treatment. Of interest to all healthcare-related professionals as well as nutritionists, and the medical community focusing on disease prevention.

Reproductive Genetics

Reproductive Genetics
Author: Sean Kehoe,Lyn Chitty,Tessa Homfray
Publsiher: RCOG
Total Pages: 242
Release: 2009-11
ISBN 10: 1906985162
ISBN 13: 9781906985165
Language: EN, FR, DE, ES & NL

Reproductive Genetics Book Review:

This book presents the findings of the RCOG Study Group findings on genetics underlying reproductive function.

Epigenetics and Epigenomics

Epigenetics and Epigenomics
Author: Christopher J. Payne
Publsiher: BoD – Books on Demand
Total Pages: 220
Release: 2014-04-29
ISBN 10: 9535113631
ISBN 13: 9789535113638
Language: EN, FR, DE, ES & NL

Epigenetics and Epigenomics Book Review:

The book aims to provide an overview of current knowledge regarding epigenetics and epigenomics. Included are reviews on the role of epigenetics in the development and pathogenesis of the vascular endothelium and nervous system, as well as our current understanding of the potential etiologies of Autism Spectrum Disorders. Additional chapters are devoted to DNA methylation, genomic imprinting and human reproduction. A discussion of the role of the epigenome in cancer prevention and polyphenols is also included. Authors provide research findings from both human data and animal model studies. This book will be of interest to scientists, physicians and lay readers wishing to review recent developments in the field of epigenetics and epigenomics.

Handbook of Fertility

Handbook of Fertility
Author: Ronald Ross Watson
Publsiher: Academic Press
Total Pages: 452
Release: 2015-04-01
ISBN 10: 9780128008720
ISBN 13: 0128008725
Language: EN, FR, DE, ES & NL

Handbook of Fertility Book Review:

Handbook of Fertility: Nutrition, Diet, Lifestyle and Reproductive Health focuses on the ways in which food, dietary supplements, and toxic agents, including alcohol and nicotine affect the reproductive health of both women and men. Researchers in nutrition, diet, epidemiology, and endocrinology will find this comprehensive resource invaluable in their long-term goal of understanding and improving reproductive health. This book brings together a broad range of experts researching the different aspects of foods and dietary supplements that promote or detract from reproductive health. Section One contains several overview chapters on fertility, how it is assessed, and how it can be affected by different metabolic states, nutritional habits, dietary supplements, the action of antioxidants, and lifestyle choices. Sections Two and Three consider how male and female fertility are affected by obesity, metabolic syndrome, hormonal imbalance, and even bariatric surgery. Section Four explores the ways diet, nutrition, and lifestyle support or retard the success of in vitro fertilization, while Section Five explores how alcohol and other drugs of abuse lower fertility in both women and men. Explores how alcohol, nicotine, and other drugs of abuse disrupt and impair reproductive health Reviews studies of common conditions such as obesity and metabolic syndrome and their effect on fertility and reproductive health Investigates the components of foods and dietary supplements, in particular oxidative stress and antioxidants Presents the nutritional effects of foods and dietary supplements and their benefits and risks relating to reproductive health

Genetics of Human Infertility

Genetics of Human Infertility
Author: P.H. Vogt
Publsiher: Karger Medical and Scientific Publishers
Total Pages: 178
Release: 2017-09-12
ISBN 10: 3318060984
ISBN 13: 9783318060980
Language: EN, FR, DE, ES & NL

Genetics of Human Infertility Book Review:

Infertility affects more than one in ten couples worldwide and is related to highly heterogeneous pathologies sometimes only discernible in the germ line. Its complex etiology often, but not always, includes genetic factors besides anatomical defects, immunological interference, and environmental aspects. Nearly 30% of infertility cases are probably caused only by genetic defects. Thereby experimental animal knockout models convincingly show that infertility can be caused by single or multiple gene defects. Translating those basic research findings into clinical studies is challenging, leaving genetic causes for the vast majority of infertility patients unexplained. Nevertheless, a large number of candidate genes have been revealed by sophisticated molecular methods. This book provides a comprehensive overview on the subject of infertility written by the leading authorities in this field. It covers topics including basic biological, cytological, and molecular studies, as well as common and uncommon syndromes. It is a must-read for human geneticists, endocrinologists, epidemiologists, zoologists, and counsellors in human genetics, infertility, and assisted reproduction.

Environmental Impacts on Reproductive Health and Fertility

Environmental Impacts on Reproductive Health and Fertility
Author: Tracey J. Woodruff,Sarah J. Janssen,Louis J. Guillette, Jr,Linda C. Giudice
Publsiher: Cambridge University Press
Total Pages: 262
Release: 2010-01-28
ISBN 10: 9780521519526
ISBN 13: 0521519527
Language: EN, FR, DE, ES & NL

Environmental Impacts on Reproductive Health and Fertility Book Review:

Many reproductive and developmental health problems are caused by exposure to chemicals that are widely dispersed in our environment. These problems include infertility, miscarriage, poor pregnancy outcomes, abnormal fetal development, early puberty, endometriosis, and diseases and cancers of reproductive organs. The compelling nature of the collective science has resulted in recognition of a new field of environmental reproductive health. Focusing on exposures to environmental contaminants, particularly during critical periods in development and their potential effects on all aspects of future reproductive life-course, this book provides the first comprehensive source of information bringing together the arguments that are spread out among various scientific disciplines in environmental health, clinical and public health fields. It provides a review of the science in key areas of the relationship between environmental contaminants and reproductive health outcomes, and recommendations on efforts toward prevention in clinical care and public policy.

Paramecium

Paramecium
Author: Geoffrey Beale,John R. Preer, Jr.
Publsiher: CRC Press
Total Pages: 216
Release: 2008-03-27
ISBN 10: 0203491904
ISBN 13: 9780203491904
Language: EN, FR, DE, ES & NL

Paramecium Book Review:

The techniques used to decipher the genetic makeup of species as well as epigenetic mechanisms are essential for explaining life forms and studying their DNA. As a eukaryotic model, Paramecium is well suited for genetic analysis. Taking a rather unconventional view of genetics, Paramecium: Genetics and Epigenetics explores how to use this protozoan as a basis for studying complex cells. The book discusses various aspects of Paramecium, including the cortex, the cytoplasm, nuclei, asexual fission, conjugation, autogamy,macronuclear regeneration, cytogamy, life cycle phases, and behavior. It examines the assorted mating types of the genus and how these mating types are determined. It also elucidates some techniques that identify genetically defined genes with the DNA from a library that comprises those genes and details the genetic, epigenetic, chemical, and molecular facets of several different traits. In addition, the authors chronicle the history and reemergence of investigating RNA and DNA in Paramecium. With many powerful tools now available, Paramecium research is entering a new frontier in molecular biology. A full account of Paramecium genetics, this book presents a wealth of time-consuming observations and remarkable phenomena that will lead to a better understanding of complex cells.