Endothelial Signaling in Vascular Dysfunction and Disease

Endothelial Signaling in Vascular Dysfunction and Disease
Author: Shampa Chatterjee
Publsiher: Academic Press
Total Pages: 274
Release: 2021-01-20
ISBN 10: 0128163828
ISBN 13: 9780128163825
Language: EN, FR, DE, ES & NL

Endothelial Signaling in Vascular Dysfunction and Disease Book Review:

Endothelial Signaling in Vascular Dysfunction and Disease: From Bench to Bedside provides a detailed understanding of the endothelium, its activation and their link to some common clinical disorders. In addition, the book covers earlier discoveries, including those from the last and 19th centuries. It is split into five sections that cover the vascular tree as an integrative structure, the endothelium in inflammation, endothelial signaling, activation and toxicity with chemotherapy, radiation induced endothelial dysfunction and vascular disease, and therapies in combating vascular diseases. Each section is discussed with a translational approach in order to make the content truly applicable. This book is a valuable source for basic researchers, clinicians in the fields of Oncology, Cardiovascular Medicine and Radiology, and members of the biomedical field who are conducting studies related to the endothelium and vascular disease. Discusses the most relevant discoveries in endothelial biology and their link to manifestations of clinical disease Presents history and diagrams in each section to highlight the original biological discovery and its link of clinical manifestations of vascular disease Includes recent findings on the relationship between endothelial signaling, chemotherapy and radiation induced endothelial dysfunction

Endothelium and Cardiovascular Diseases

Endothelium and Cardiovascular Diseases
Author: Protasio Lemos Da Luz,Peter Libby,Francisco Rafael Martins Laurindo,Antonio Carlos Palandri Chagas
Publsiher: Academic Press
Total Pages: 758
Release: 2018-02-03
ISBN 10: 0128125519
ISBN 13: 9780128125519
Language: EN, FR, DE, ES & NL

Endothelium and Cardiovascular Diseases Book Review:

Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians. Provides a complete overview of endothelial function in health and diseases, along with an assessment of new information Includes coverage of groundbreaking areas, including the artificial LDL particle, the development of a new anti-erectile dysfunction agent, a vaccine for atherosclerosis, coronary calcification associated with red wine, and the interplay of endoplasmic reticulum/oxidative stress Explores the genetic features of endothelium and the interaction between basic knowledge and clinical syndromes

Mechanisms of Vascular Disease

Mechanisms of Vascular Disease
Author: Robert Fitridge,Matthew Thompson
Publsiher: University of Adelaide Press
Total Pages: 587
Release: 2011-01-01
ISBN 10: 1922064009
ISBN 13: 9781922064004
Language: EN, FR, DE, ES & NL

Mechanisms of Vascular Disease Book Review:

New updated edition first published with Cambridge University Press. This new edition includes 29 chapters on topics as diverse as pathophysiology of atherosclerosis, vascular haemodynamics, haemostasis, thrombophilia and post-amputation pain syndromes.

Endothelial Dysfunction

Endothelial Dysfunction
Author: Helena Lenasi
Publsiher: BoD – Books on Demand
Total Pages: 430
Release: 2018-10-24
ISBN 10: 1789842530
ISBN 13: 9781789842531
Language: EN, FR, DE, ES & NL

Endothelial Dysfunction Book Review:

The endothelium enables communication between blood and tissues and is actively involved in cardiovascular homeostasis. Endothelial dysfunction has been recognized as an early step in the development of cardiovascular diseases: respectively, endothelium represents a potential therapeutic niche with multiple targets. The purpose of the book is to point out some recent findings of endothelial physiology and pathophysiology emphasizing various aspects of endothelial dysfunction connected to the body's internal and external environment. While basic features of the endothelium are presented in an introductory chapter, the authors of the following 17 chapters have provided extensive insight into some selected topics of endothelial (dys)function. The book would hopefully be useful for anyone interested in recapitulating endothelial (patho)physiology and expanding knowledge of molecular mechanisms involved in endothelial dysfunction, relevant also for further clinical investigations.

The Immunology of Cardiovascular Homeostasis and Pathology

The Immunology of Cardiovascular Homeostasis and Pathology
Author: Susanne Sattler,Teresa Kennedy-Lydon
Publsiher: Springer
Total Pages: 274
Release: 2017-07-11
ISBN 10: 3319576135
ISBN 13: 9783319576138
Language: EN, FR, DE, ES & NL

The Immunology of Cardiovascular Homeostasis and Pathology Book Review:

Cardiovascular immunology is a newly emerging research area, investigating the crosstalk between the cardiovascular and the immune system. This crosstalk is evident through (1) crucial immunological capacities and functions of cardiovascular cell types, including cardiomyocytes, fibroblasts, endothelial cells, pericytes and cardiac resident macrophages, (2) the impact of aberrant immune function on the development of cardiovascular disease such as atherosclerosis, direct and indirect immune-mediated heart disease and vasculitis, and (3) the crucial role of the immune system in cardiac repair and regeneration. The Immunology of Cardiovascular Homeostasis and Pathology covers all these aspects of cardiovascular immunology, starting with homeostatic immunological functions of traditional cardiovascular cell types, and moving then to the role of the immune system in cardiovascular pathology and to recent research into targeting the immune system to boost cardiac healing and regeneration.

Ion Channels and Calcium Signaling in the Microcirculation

Ion Channels and Calcium Signaling in the Microcirculation
Author: William F. Jackson
Publsiher: Academic Press
Total Pages: 310
Release: 2020-06
ISBN 10: 0128200901
ISBN 13: 9780128200902
Language: EN, FR, DE, ES & NL

Ion Channels and Calcium Signaling in the Microcirculation Book Review:

Ion Channels and Calcium Signaling in the Microcirculation, Volume 85, the latest release in the Current Topics in Membranes series, highlights the latest advances in the expression and function of ion channels and calcium signaling in vascular smooth muscle and endothelial cells in resistance arteries, arterioles and capillaries, critical components of microcirculation, the business end of the cardiovascular system. Leading experts have contributed chapters, including Smooth muscle ion channels and calcium signaling in the regulation of striated muscle arteriolar tone; Endothelial KIR channels as a key component of shear stress-induced mechanotransduction; Endothelial TRPV4 channels and vasodilator reactivity, and much more. Additional sections cover cerebral capillary endothelial TRPA channels and the regulation of blood flow; Endothelial mineralocorticoid receptors and the regulation of TRPV4 function in cerebral parenchymal arterioles in hypertension; Subcellular calcium signaling and myogenic tone development in the retinal microcirculation; Microvascular KIR channels: Basis, properties and regulation by lipid and hemodynamic forces, Ion channels and calcium signaling in capillary endothelial cells; Ion channels and calcium signaling in bladder arterioles and resistance arteries, and Myoendothelial feedback and endothelial IKCa and sKCa channels.

Pediatric Hypertension

Pediatric Hypertension
Author: Ronald J. Portman,Jonathan M. Sorof,Julie R. Ingelfinger
Publsiher: Springer Science & Business Media
Total Pages: 492
Release: 2004-06-12
ISBN 10: 1592597971
ISBN 13: 9781592597970
Language: EN, FR, DE, ES & NL

Pediatric Hypertension Book Review:

The importance of hypertension in children and adolescents is becoming incre- ingly recognized by physicians and scientists in the 21st century. However, in contrast to the attention that hypertension has received in the adult population for the past three decades since the first Joint National Committee (JNC) report, research and clinical knowledge that involves hypertension in children is still very much in its own childhood. Pediatric Hypertension, edited by Drs. Portman, Sorof, and Ingelfinger, is undoubtedly the most up-to-date and clinically relevant contribution to the field of hypertension in children available because it brings together the numerous pathophysiologic, diagnostic, and therapeutic advances in the evaluation of high blood pressure in infants, children, and adolescents. The editors have carefully organized their volume into sections that cover blood pressure regulation in infants and children, blood pressure measurement issues, pat- physiology and clinical assessment for essential and secondary forms of hypertension during childhood, and nonpharmacologic and pharmacologic approaches to the tre- ment of hypertension in children.

Vascular Development

Vascular Development
Author: Derek J. Chadwick,Jamie A. Goode
Publsiher: John Wiley & Sons
Total Pages: 260
Release: 2007-08-20
ISBN 10: 0470319429
ISBN 13: 9780470319420
Language: EN, FR, DE, ES & NL

Vascular Development Book Review:

The formation of blood vessels is an essential aspect of embryogenesis in vertebrates. It is a central feature of numerous post-embryonic processes, including tissue and organ growth and regeneration. It is also part of the pathology of tumour formation and certain inflammatory conditions. In recent years, comprehension of the molecular genetics of blood vessel formation has progressed enormously and studies in vertebrate model systems, especially the mouse and the zebrafish, have identified a common set of molecules and processes that are conserved throughout vertebrate embryogenesis while, in addition, highlighting aspects that may differ between different animal groups. The discovery in the past decade of the crucial role of new blood vessel formation for the development of cancers has generated great interest in angiogenesis (the formation of new blood vessels from pre-existing ones), with its major implications for potential cancer-control strategies. In addition, there are numerous situations where therapeutic treatments either require or would be assisted by vasculogenesis (the de novo formation of blood vessels). In particular, post-stroke therapies could include treatments that stimulate neovascularization of the affected tissues. The development of such treatments, however, requires thoroughly understanding the developmental properties of endothelial cells and the basic biology of blood vessel formation. While there are many books on angiogenesis, this unique book focuses on exactly this basic biology and explores blood vessel formation in connection with tissue development in a range of animal models. It includes detailed discussions of relevant cell biology, genetics and embryogenesis of blood vessel formation and presents insights into the cross-talk between developing blood vessels and other tissues. With contributions from vascular biologists, cell biologists and developmental biologists, a comprehensive and highly interdisciplinary volume is the outcome.

Sudden Coronary Death

Sudden Coronary Death
Author: Henry M. Greenberg,Edward M. Dwyer
Publsiher: Unknown
Total Pages: 484
Release: 1982
ISBN 10: 9780897661539
ISBN 13: 0897661532
Language: EN, FR, DE, ES & NL

Sudden Coronary Death Book Review:

Calcium and Signal Transduction

Calcium and Signal Transduction
Author: Anonim
Publsiher: BoD – Books on Demand
Total Pages: 202
Release: 2018-10-24
ISBN 10: 1789842492
ISBN 13: 9781789842494
Language: EN, FR, DE, ES & NL

Calcium and Signal Transduction Book Review:

Since the development of microelectronic clamping methodology and fluorescent indicators for direct measurement of dynamic intracellular calcium transients, our understanding of biological signal transduction has progressed dramatically since the 1980s. Calcium is a universal signal in biology that modulates gene expression, transmitter and hormone release, muscular movement, and even "programmed" cell death. This book represents a compilation of chapters from a diverse set of expert biologists throughout the world who have conducted research in the general area of calcium signaling in organisms ranging from bacteria to humans. In accord with priorities of resolving human disease, the reader will also benefit from learning calcium's role in cellular signaling pathology relating to acute or chronic conditions such as vomiting, sepsis, obesity, hypertension, and cancer.

Endothelium

Endothelium
Author: Ayse Basak Engin,Atilla Engin
Publsiher: CRC Press
Total Pages: 468
Release: 2013-05-29
ISBN 10: 1466582790
ISBN 13: 9781466582798
Language: EN, FR, DE, ES & NL

Endothelium Book Review:

The function and life span of endothelial cells have a large impact upon the quality and expectancy of an individual's life. During low perfusion, the adaptation of different cells to hypoxia precipitate the aggressive progression of diseases. Although the clinical studies have convincingly shown that endothelial dysfunction occurs whenever the biological functions or bioavailability of nitric oxide are impaired, in all these scenarios, the role of endothelial cell-destructive process cross-talk is yet poorly understood. This book focuses on the contribution of molecular mechanisms to endothelial dysfunction in related metabolic disorders.

Biomedical Index to PHS supported Research

Biomedical Index to PHS supported Research
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1994
ISBN 10:
ISBN 13: MINN:31951P003778522
Language: EN, FR, DE, ES & NL

Biomedical Index to PHS supported Research Book Review:

The Endothelium

The Endothelium
Author: Thomas F. Luscher,Paul M. Vanhoutte
Publsiher: CRC Press
Total Pages: 228
Release: 2020-04-15
ISBN 10: 1000083314
ISBN 13: 9781000083316
Language: EN, FR, DE, ES & NL

The Endothelium Book Review:

First published in 1990: The Endothelium: Modulator of Cardiovascular Function takes a comprehensive look at the role of the endothelium in cardiovascular control in health and disease. Experts offer detailed reviews on specific topics that address these roles of the endothelium: diffusion barrier, blood-brain barrier, regulator of capillary permeability, metabolic function (uptake and enzymatic destruction), conversion of vasoactive products, production of prostanoids, production and release of endothelium-derived relaxing factors, production of endothelium-derived contracting factors, production of coagulation factors, production of fibrinolytic factors, reticulo-endothelial function, role in atherosclerosis, and changes in function with aging and disease. This overview provides the reader with an update on the role of one of the most fascinating cells in cardiovascular biology. It focuses on the multiple functions of those cells and offers the first attempt to draw a parallel between these functions. Anyone studying the fields of physiology and pharmacology will benefit from this "must have" reference resource.

Endothelial Dysfunction and Inflammation

Endothelial Dysfunction and Inflammation
Author: Shauna Dauphinee,Aly Karsan
Publsiher: Springer Science & Business Media
Total Pages: 234
Release: 2010-09-24
ISBN 10: 3034601689
ISBN 13: 9783034601689
Language: EN, FR, DE, ES & NL

Endothelial Dysfunction and Inflammation Book Review:

Endothelial dysfunction is broadly defined as a disruption of the balance between vasoactive mediators and a propensity towards an inflammatory state. This volume provides an overview of the fields of endothelial dysfunction and inflammation through the discussion of topics ranging from the molecular biology of activated endothelial cells to the endothelium in inflammatory disease and therapeutic approaches targeting endothelial dysfunction. Topics include: Heterogeneity of the endothelium during inflammation, oxidative stress and endothelial dysfunction, biology and regulation of nitric oxide in inflammatory pathologies, endothelial dysfunction in inflammatory diseases, such as diabetes and atherosclerosis and Clinical methods used to assess endothelial function. This book brings together basic and clinical research to assist the reader in bridging connections from bench-to-bedside. Written by expert researchers in the fields of endothelial biology, inflammation research and clinical science, it serves as a useful reference for academic and industrial researchers, clinicians, and trainees in the medical profession.

Endothelial Function in Hypertension

Endothelial Function in Hypertension
Author: David Webb,Patrick Vallance
Publsiher: Springer Science & Business Media
Total Pages: 154
Release: 2012-12-06
ISBN 10: 3642608116
ISBN 13: 9783642608117
Language: EN, FR, DE, ES & NL

Endothelial Function in Hypertension Book Review:

The vascular endothelium has become an increasing focus of research over the last 15 years. Nitric oxide and endothelin appear to have important and opposing actions on vascular tone, smooth muscle proliferation and platelet/monocyte activation, and endothelial dysfunction affecting the L-arginine/nitric oxide and endothelin systems both appear to be crucial to atherogenesis and to the pathophysiology of many forms of cardiovascular disease. Additionally, a number of new drugs of major clinical interest are now emerging that act favourably to modulate endothelial function and alter the outcome in these conditions. Here, a synthesis of the current understanding of endothelial dysfunction in hypertension and related disorders - and future therapeutic prospects - has been drawn together by a series of internationally recognised leaders in the field.

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 329
Release: 1998
ISBN 10:
ISBN 13: UIUC:30112047003154
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Review:

Pathophysiology and Pharmacotherapy of Cardiovascular Disease

Pathophysiology and Pharmacotherapy of Cardiovascular Disease
Author: Gowraganahalli Jagadeesh,Pitchai Balakumar,Khin Maung-U
Publsiher: Springer
Total Pages: 1342
Release: 2015-05-06
ISBN 10: 3319159615
ISBN 13: 9783319159614
Language: EN, FR, DE, ES & NL

Pathophysiology and Pharmacotherapy of Cardiovascular Disease Book Review:

The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension
Author: Toshio Nakanishi,H. Scott Baldwin,Jeffrey R. Fineman,Hiroyuki Yamagishi
Publsiher: Springer Nature
Total Pages: 374
Release: 2020-01-01
ISBN 10: 9811511853
ISBN 13: 9789811511851
Language: EN, FR, DE, ES & NL

Molecular Mechanism of Congenital Heart Disease and Pulmonary Hypertension Book Review:

This open access book focuses on the molecular mechanism of congenital heart disease and pulmonary hypertension, offering new insights into the development of pulmonary circulation and the ductus arteriosus. It describes in detail the molecular mechanisms involved in the development and morphogenesis of the heart, lungs and ductus arteriosus, covering a range of topics such as gene functions, growth factors, transcription factors and cellular interactions, as well as stem cell engineering technologies. The book also presents recent advances in our understanding of the molecular mechanism of lung development, pulmonary hypertension and molecular regulation of the ductus arteriosus. As such, it is an ideal resource for physicians, scientists and investigators interested in the latest findings on the origins of congenital heart disease and potential future therapies involving pulmonary circulation/hypertension and the ductus arteriosus.

Physiologic and Pathologic Angiogenesis

Physiologic and Pathologic Angiogenesis
Author: Dan Simionescu,Agneta Simionescu
Publsiher: BoD – Books on Demand
Total Pages: 464
Release: 2017-04-05
ISBN 10: 9535130234
ISBN 13: 9789535130239
Language: EN, FR, DE, ES & NL

Physiologic and Pathologic Angiogenesis Book Review:

The purpose of this book is to highlight novel advances in the field and to incentivize scientists from a variety of fields to pursue angiogenesis as a research avenue. Blood vessel formation and maturation to capillaries, arteries, or veins is a fascinating area which can appeal to multiple scientists, students, and professors alike. Angiogenesis is relevant to medicine, engineering, pharmacology, and pathology and to the many patients suffering from blood vessel diseases and cancer, among others. We are hoping that this book will become a source of inspiration and novel ideas for all.

Textbook of Vascular Medicine

Textbook of Vascular Medicine
Author: Rhian M. Touyz,Christian Delles
Publsiher: Springer
Total Pages: 503
Release: 2019-08-02
ISBN 10: 3030164810
ISBN 13: 9783030164812
Language: EN, FR, DE, ES & NL

Textbook of Vascular Medicine Book Review:

This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.