Developmental and Fetal Origins of Differences in Monozygotic Twins

Developmental and Fetal Origins of Differences in Monozygotic Twins
Author: Alexandra Matias,Isaac Blickstein
Publsiher: Academic Press
Total Pages: 386
Release: 2020-05-15
ISBN 10: 0128203072
ISBN 13: 9780128203071
Language: EN, FR, DE, ES & NL

Developmental and Fetal Origins of Differences in Monozygotic Twins Book Review:

Developmental and Fetal Origins of Differences in Monozygotic Twins: From Genetics to Environmental Factors examines the major causes of discordance in monozygotic twins, from genetic, to environmental influences, including discussions on the genetic, epigenetic, fetal and environmental factors. Twin differences discussed include malformations, deformations and disruptions secondary to inequitable division of the early embryo, chromosome and single gene mosaicism, Nonrandom X chromosome inactivation, mitochondrial heteroplasmy, epigenetic variation, and variable and inequitable blood supply, among other influences. Differences in hemoglobin levels, placentation and amniotic fluid are also examined, while full color images illustrate discordant anomalies and twin differences throughout. Examines the major causes of discordance in monozygotic twins and their relevance for future studies and clinical management Discusses NIPT in MZ twins, twin imaging during fetal development, blood tests and forensic analysis Features contributions from international experts in twin genetics and developmental biology

Perinatology

Perinatology
Author: Renato Augusto Moreira de Sá
Publsiher: Springer Nature
Total Pages: 135
Release: 2022
ISBN 10: 3030834344
ISBN 13: 9783030834340
Language: EN, FR, DE, ES & NL

Perinatology Book Review:

Multifaceted Genes in Amyotrophic Lateral Sclerosis Frontotemporal Dementia

Multifaceted Genes in Amyotrophic Lateral Sclerosis Frontotemporal Dementia
Author: Henry Houlden,Alan Edward Renton,Francesca Luisa Conforti
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-06-28
ISBN 10: 2889669041
ISBN 13: 9782889669042
Language: EN, FR, DE, ES & NL

Multifaceted Genes in Amyotrophic Lateral Sclerosis Frontotemporal Dementia Book Review:

Gamete and Embryo fetal Origins of Adult Diseases

Gamete and Embryo fetal Origins of Adult Diseases
Author: He-Feng Huang,Jian-Zhong Sheng
Publsiher: Springer Science & Business Media
Total Pages: 222
Release: 2013-11-19
ISBN 10: 9400777728
ISBN 13: 9789400777729
Language: EN, FR, DE, ES & NL

Gamete and Embryo fetal Origins of Adult Diseases Book Review:

The book Gamete and Embryo-fetal Origins of Adult Diseases introduces various diseases resulting from the abnormal gametogenesis and embryo development, which manifests as growth retardation, birth defects, or increased susceptibility to chronic metabolic diseases such as diabetes, cardiovascular disease and cancer in childhood and adult life, even fertility disorders and the risk of transgenerational transmission. Six common kinds of these diseases are discussed in separate chapters. The authors explore the connections between these diseases and epigenetic reprogramming, rapid cell differentiation and organ formation and environmental influences, including assisted reproductive technology and adverse intrauterine environments. With a summary of findings on the causes and progression of adult diseases at the phase of gametogenesis and embryo development, this book provides insights into the pathogenesis of disease and aids in the treatment and prevention of disease, meeting the requirement for improving the quality of the newborn population, and effectively preventing and curing major diseases at an early stage. This book offers new perspectives and will be an enlightening resource for obstetricians, paediatricians, epidemiologists, endocrinologists and sanitarians. Editor He-Feng Huang, M.D., is Professor and President of Women’s Hospital, School of Medicine, Zhejiang University, China. Editor Jian-Zhong Sheng, Ph.D., is Professor at the Department of Pathology & Pathophysiology, School of Medicine, Zhejiang University, China.

Medical Epigenetics

Medical Epigenetics
Author: Anonim
Publsiher: Academic Press
Total Pages: 970
Release: 2021-08-27
ISBN 10: 0128243260
ISBN 13: 9780128243268
Language: EN, FR, DE, ES & NL

Medical Epigenetics Book Review:

Medical Epigenetics, Second Edition provides a comprehensive analysis of epigenetics in health management, across a broad spectrum of disease categories and specialties, and with a focus on human systems, epigenetic diseases that affect these systems, and evolving modes of epigenetic-based treatment. Here, more than 40 leading researchers examine how each human system is affected by epigenetic maladies, offering an all-in-one resource on medical epigenetics not only for those directly involved with health care, but investigators in life sciences, biotech companies, graduate students, and others who are interested in applied aspects of epigenetics. Incorporating both diagnostic and prognostic epigenetic approaches, this volume also fully supports the application of epigenetics in precision medicine. This second edition of Medical Epigenetics, a volume in the Translational Epigenetics series, has been fully revised to address recent advances in disease epigenetics and role of epigenetics in precision medicine, with all-new chapters on skin cancer epigenetics, network analysis in medical epigenetics, machine learning in epigenetic diseases, and clinical trials of epigenetics drugs. Features chapters from leading researchers and clinicians dedicated to the burgeoning role of epigenetics in medical practice Covers emerging topics, including twin epigenetics, as well as epigenetics of gastrointestinal disease, muscle disorders, endocrine disorders, ocular medicine, pediatric diseases, sports medicine, noncoding RNA therapeutics, pain management and regenerative medicine Organized from system disorders to multi-system disorders that involve epigenetic aberrations Examines the role of epigenetics in precision medicine

RUNX Proteins in Development and Cancer

RUNX Proteins in Development and Cancer
Author: Yoram Groner,Yoshiaki Ito,Paul Liu,James C. Neil,Nancy A. Speck,Andre van Wijnen
Publsiher: Springer
Total Pages: 515
Release: 2017-03-15
ISBN 10: 9811032335
ISBN 13: 9789811032332
Language: EN, FR, DE, ES & NL

RUNX Proteins in Development and Cancer Book Review:

This volume provides the reader with an overview of the diverse functions of the RUNX family of genes. As highlighted in the introduction and several of the 29 chapters, humans and other mammals have three RUNX genes that are known to play specific roles in blood, bone and neuronal development. However, their evolutionary history has recently been traced back to unicellular organisms and their involvement in many well-known signaling pathways (Wnt, TGFb, Notch, Hippo) is indicative of a more general function in cell biology. Their documented roles in cell fate decisions include control of proliferation, differentiation, survival, senescence and autophagy. The pleiotropic effects of RUNX in development are mirrored in cancer, where RUNX genes can function as oncogenes that collaborate strongly with Myc family oncogenes or as tumour suppressor genes. In the latter role, they display hallmarks of both ‘gatekeepers’ that modulate p53 responses and ‘caretakers’ that protect the genome from DNA damage. Several chapters focus on the importance of these genes in leukemia research, where RUNX1 and CBFB are frequently affected by chromosomal translocations that generate fusion oncoproteins, while recent studies suggest wider roles for RUNX modulation in solid cancers. Moreover, RUNX genes are intimately involved in the development and regulation of the immune system, while emerging evidence suggests a role in innate immunity to infectious agents, including HIV. At the biochemical level, the RUNX family can serve as activators or repressors of transcription and as stable mediators of epigenetic memory through mitosis. Not surprisingly, RUNX activity is controlled at multiple levels, this includes miRNAs and a plethora of post-translational modifications. Several chapters highlight the interplay between the three mammalian RUNX genes, where cross-talk and partial functional redundancies are evident. Finally, structural analysis of the RUNX/CBFB interaction has led to the development of small molecule inhibitors that provide exciting new tools to decipher the roles of RUNX in development and as targets for therapy. This volume provides a compendium and reference source that will be of broad interest to cancer researchers, developmental biologists and immunologists.

Family Matters

Family Matters
Author: Gita D. Mishra
Publsiher: Oxford University Press
Total Pages: 341
Release: 2009-04-02
ISBN 10: 0199231036
ISBN 13: 9780199231034
Language: EN, FR, DE, ES & NL

Family Matters Book Review:

Life course epidemiology considers how adult health is affected by a variety of factors and influences over the entire life-course. This book provides the reader with the knowledge and skills to design, analyse, and correctly interpret family-based studies, which are increasingly being used to explore life course epidemiology.

Exploring the Biological Contributions to Human Health

Exploring the Biological Contributions to Human Health
Author: Institute of Medicine,Board on Health Sciences Policy,Committee on Understanding the Biology of Sex and Gender Differences
Publsiher: National Academies Press
Total Pages: 288
Release: 2001-07-02
ISBN 10: 9780309132978
ISBN 13: 0309132975
Language: EN, FR, DE, ES & NL

Exploring the Biological Contributions to Human Health Book Review:

It's obvious why only men develop prostate cancer and why only women get ovarian cancer. But it is not obvious why women are more likely to recover language ability after a stroke than men or why women are more apt to develop autoimmune diseases such as lupus. Sex differences in health throughout the lifespan have been documented. Exploring the Biological Contributions to Human Health begins to snap the pieces of the puzzle into place so that this knowledge can be used to improve health for both sexes. From behavior and cognition to metabolism and response to chemicals and infectious organisms, this book explores the health impact of sex (being male or female, according to reproductive organs and chromosomes) and gender (one's sense of self as male or female in society). Exploring the Biological Contributions to Human Health discusses basic biochemical differences in the cells of males and females and health variability between the sexes from conception throughout life. The book identifies key research needs and opportunities and addresses barriers to research. Exploring the Biological Contributions to Human Health will be important to health policy makers, basic, applied, and clinical researchers, educators, providers, and journalists-while being very accessible to interested lay readers.

Developmental Origins of Health and Disease

Developmental Origins of Health and Disease
Author: Peter Gluckman,Mark Hanson
Publsiher: Cambridge University Press
Total Pages: 542
Release: 2006-04-20
ISBN 10: 9780521847438
ISBN 13: 0521847435
Language: EN, FR, DE, ES & NL

Developmental Origins of Health and Disease Book Review:

This landmark publication provides the first definitive account of how and why subtle influences on the fetus and during early life can have such profound consequences for adult health and diseases. Although the epidemiological evidence for this link has long proved compelling, it is only much more recently that the scientific and physiological basis has begun to be studied in depth and fully understood. The compilation, written by many of the world's leading experts in this exciting field, summarizes these scientific and clinical advances.

Fanaroff and Martin s Neonatal Perinatal Medicine E Book

Fanaroff and Martin s Neonatal Perinatal Medicine E Book
Author: Richard J. Martin,Avroy A. Fanaroff,Michele C. Walsh
Publsiher: Elsevier Health Sciences
Total Pages: 1850
Release: 2019-04-11
ISBN 10: 0323567096
ISBN 13: 9780323567091
Language: EN, FR, DE, ES & NL

Fanaroff and Martin s Neonatal Perinatal Medicine E Book Book Review:

Trusted by physicians and advanced practice providers through ten standard-setting editions, Fanaroff and Martin's Neonatal-Perinatal Medicine, 11th Edition, remains the reference of choice for expert, multidisciplinary guidance on the management and evidence-based treatment of problems in the mother, fetus, and neonate. An expanded team of international authors, led by Drs. Richard J. Martin, Avroy A. Fanaroff, and Michele C. Walsh of Rainbow Babies and Children's Hospital, brings you up to date with advances in the control of nosocomial infections in preterm infants, genetic disorders and birth defects, the fetal origins of adult disease, the late preterm infants, and much more – all designed to help you improve the quality of life and long-term outcomes of your patients. Helps you make informed clinical choices for each patient – from diagnosis and treatment selection through post-treatment strategies and management of complications – with a dual focus on neonatology and perinatology. Includes a new chapter on Social and Economic Contributors to Neonatal Outcome. Features extensive updates and reorganization throughout, with new Key Points at the end of each chapter Provides up-to-date, evidence-based content, with more information on precision medicine and genetics. Uses detailed, full-color illustrations that depict disorders in the clinical setting and explain complex information. Remains the most comprehensive, multidisciplinary text in the field – an excellent source of information for every stage of your practice.

Chromosomal Translocations and Genome Rearrangements in Cancer

Chromosomal Translocations and Genome Rearrangements in Cancer
Author: Janet D. Rowley,Michelle M. Le Beau,Terence H. Rabbitts
Publsiher: Springer
Total Pages: 490
Release: 2015-12-09
ISBN 10: 3319199838
ISBN 13: 9783319199832
Language: EN, FR, DE, ES & NL

Chromosomal Translocations and Genome Rearrangements in Cancer Book Review:

This volume collates world experts’ insights into the molecular biology of cancer chromosomes, their abnormalities and the subsequent cellular consequences. Exploring themes involving oncogenes, such as by chromosomal translocations, other genome rearrangements and somatic mutations, this book is a review of the field of cancer genetics that presages a new era, as whole genome sequencing becomes more accessible. The work begins with a look at historical themes, such as the analysis of metaphase chromosomes using microscopy and staining techniques, advances in which provided our first broad glimpse into the genetic anatomy of a malignant cell. Readers will learn about the application of DNA molecular cloning techniques in the 1980s, that led to the identification of the genes involved in the Philadelphia and Burkitt's lymphoma chromosomal translocations, solidifying the role of oncogenes and tumour suppressor genes in cancer aetiology via chromosomal alterations and which launched a field in cancer genetics. Subsequent chapters bring the reader up to date by reviewing recent developments in the field, with dedicated sections on leukaemia/lymphoma, sarcomas and epithelial tumours. Contributions feature numerous colour tables and illustrations and this volume will provide a basis for understanding cancer chromosomes for many years to come.

BMJ

BMJ
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1995
ISBN 10: 1928374650XXX
ISBN 13: UCLA:L0074027269
Language: EN, FR, DE, ES & NL

BMJ Book Review:

Fetal Embryonic Hematopoietic Progenitors and Their Impact on Adult Diseases

Fetal Embryonic Hematopoietic Progenitors and Their Impact on Adult Diseases
Author: Silvia Brunelli,Antonella Ellena Ronchi,Charlotta Boiers,Emanuele Azzoni
Publsiher: Frontiers Media SA
Total Pages: 135
Release: 2021-10-01
ISBN 10: 2889714578
ISBN 13: 9782889714575
Language: EN, FR, DE, ES & NL

Fetal Embryonic Hematopoietic Progenitors and Their Impact on Adult Diseases Book Review:

Old and New Perspectives on Mortality Forecasting

Old and New Perspectives on Mortality Forecasting
Author: Tommy Bengtsson,Nico Keilman
Publsiher: Springer
Total Pages: 349
Release: 2019-03-28
ISBN 10: 3030050750
ISBN 13: 9783030050757
Language: EN, FR, DE, ES & NL

Old and New Perspectives on Mortality Forecasting Book Review:

This open access book describes methods of mortality forecasting and discusses possible improvements. It contains a selection of previously unpublished and published papers, which together provide a state-of-the-art overview of statistical approaches as well as behavioural and biological perspectives. The different parts of the book provide discussions of current practice, probabilistic forecasting, the linearity in the increase of life expectancy, causes of death, and the role of cohort factors. The key question in the book is whether it is possible to project future mortality accurately, and if so, what is the best approach. This makes the book a valuable read to demographers, pension planners, actuaries, and all those interested and/or working in modelling and forecasting mortality.

Contemporary Gynecologic Practice

Contemporary Gynecologic Practice
Author: Atef Darwish
Publsiher: BoD – Books on Demand
Total Pages: 244
Release: 2015-02-04
ISBN 10: 953511736X
ISBN 13: 9789535117360
Language: EN, FR, DE, ES & NL

Contemporary Gynecologic Practice Book Review:

Gynecology is frequently changing due to extensive implementation of high technology in both, the diagnosis and management of gynecologic problems. General gynecologists, gynecologic endocrinologists, infertility specialists, gynecologic endoscopists, and gynecologic oncologists will find attractive, new information in this book.

Principles of Sex based Differences in Physiology

Principles of Sex based Differences in Physiology
Author: Virginia M. Miller,Virginia L. Miller,Meredith Hay
Publsiher: Gulf Professional Publishing
Total Pages: 333
Release: 2004
ISBN 10: 9780444514974
ISBN 13: 044451497X
Language: EN, FR, DE, ES & NL

Principles of Sex based Differences in Physiology Book Review:

Differences in physiology between men and women extend far beyond differences in reproductive functions. Medical literature abounds in descriptions of differences in prevalence, symptoms and severity of diseases between men and women including heart attack, rheumatic diseases, gastrointestinal disease and osteoporosis. Much of the information is descriptive rather than mechanistic and scattered throughout a variety of books, review articles and original papers. This book provides a single source that summarizes current basic mechanisms of gene/hormone interactions and their subsequent impact on physiological functions. It is an ideal source material to be used in training the next generation of physician/scientists who will develop a more individualized approach to prevention, diagnosis and therapeutic medical practice.

Environmental Epigenetics

Environmental Epigenetics
Author: L. Joseph Su,Tung-chin Chiang
Publsiher: Springer
Total Pages: 321
Release: 2015-05-18
ISBN 10: 1447166787
ISBN 13: 9781447166788
Language: EN, FR, DE, ES & NL

Environmental Epigenetics Book Review:

This book examines the toxicological and health implications of environmental epigenetics and provides knowledge through an interdisciplinary approach. Included in this volume are chapters outlining various environmental risk factors such as phthalates and dietary components, life states such as pregnancy and ageing, hormonal and metabolic considerations and specific disease risks such as cancer cardiovascular diseases and other non-communicable diseases. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses. Environmental Epigenetics imparts integrative knowledge of the science of epigenetics and the issues raised in environmental epidemiology. This book is intended to serve both as a reference compendium on environmental epigenetics for scientists in academia, industry and laboratories and as a textbook for graduate level environmental health courses.

Handbook of Behavior Genetics

Handbook of Behavior Genetics
Author: Yong-Kyu Kim
Publsiher: Springer Science & Business Media
Total Pages: 564
Release: 2009-03-25
ISBN 10: 0387767274
ISBN 13: 9780387767277
Language: EN, FR, DE, ES & NL

Handbook of Behavior Genetics Book Review:

This handbook provides research guidelines to study roles of the genes and other factors involved in a variety of complex behaviors. Utilizing methodologies and theories commonly used in behavior genetics, each chapter features an overview of the selected topic, current issues, as well as current and future research.

Cumulated Index Medicus

Cumulated Index Medicus
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 1966
ISBN 10: 1928374650XXX
ISBN 13: COLUMBIA:HR02000903
Language: EN, FR, DE, ES & NL

Cumulated Index Medicus Book Review:

Twins From Fetus to Child

Twins   From Fetus to Child
Author: Alessandra Piontelli
Publsiher: Routledge
Total Pages: 256
Release: 2012-09-10
ISBN 10: 1134504942
ISBN 13: 9781134504947
Language: EN, FR, DE, ES & NL

Twins From Fetus to Child Book Review:

Though much has been written about twins, very little research has been done into their everyday lives, both postnatal and prenatal. In this fascinating new study Alessandra Piontelli follows the development and behaviour of thirty pairs of twins from their early life in the womb through to their third year of childhood. Drawing on detailed ultrasound observations and work with mothers and families in clinical and natural settings, the text traces the subtle ways in which various types of twins live, behave and interact with their unequally shared and unique pre- and postnatal environments. Piontelli shows how from early on distinctive and personal traits can be seen in the behaviour of each member of a twin couple and how these traits continue and strengthen well beyond birth. The book describes not only the behaviour of the twins, but the impact they have on the lives of their family and carers - what family members say, how they react and how the family changes. Scientifically based, but warmly human in content, this unique longitudinal study offers new insight for professionals working with mothers and families of twins and for researchers in human development across a range of disciplines.