Detection and Identification of Designer Drugs

Detection and Identification of Designer Drugs
Author: Brian F Thomas
Publsiher: Elsevier
Total Pages: 150
Release: 2017-11-01
ISBN 10: 0128118156
ISBN 13: 9780128118153
Language: EN, FR, DE, ES & NL

Detection and Identification of Designer Drugs Book Review:

Detection and Identification of Designer Drugs, a title in the Emerging Issues in Analytical Chemistry series, presents both an overview and a guide to techniques for anyone studying or engaging in designer drug analysis. Proliferation of the synthesis and use of designer drugs is a serious public health problem with social, economic and legal implications. Whether abuse is studied at the population level or the individual level, researchers need both background and highly detailed technical information on specific drugs and drug classes in order to combat the proliferation and highly damaging consequences of these substances. Author Brian F. Thomas provides a comprehensive discussion that emphasizes the potential threat to society, presents the ongoing challenges confronting the various laboratory approaches to detection and identification of new chemical entities and informs the development of improved analytical solutions for use in legislation, law enforcement and treatment. Summarizes the literature and evaluates the strengths and weaknesses of analytical methods for detecting and identifying designer drugs Offers authoritative information from author Brian F. Thomas, an expert with over 30 years of experience in the field Directs the reader to sources of further reading at the conclusion of each chapter Emphasizes the potential threat to society and presents ongoing challenges confronting various laboratory approaches to detection and identification of new chemical entities

Chromatographic Techniques in the Forensic Analysis of Designer Drugs

Chromatographic Techniques in the Forensic Analysis of Designer Drugs
Author: Teresa Kowalska,Mieczyslaw Sajewicz,Joseph Sherma
Publsiher: CRC Press
Total Pages: 478
Release: 2018-01-31
ISBN 10: 1315313162
ISBN 13: 9781315313160
Language: EN, FR, DE, ES & NL

Chromatographic Techniques in the Forensic Analysis of Designer Drugs Book Review:

There is a dramatic rise of novel drug use due to the increased popularity of so-called designer drugs. These synthetic drugs can be illegal in some countries, but legal in others and novel compounds unknown to drug chemistry emerge monthly. This thoughtfully constructed edited reference presents the main chromatographic methodologies and strategies used to discover and analyze novel designer drugs contained in diverse biological materials. The methods are based on molecular characteristics of the drugs belonging to each individual class of compounds, so it will be clear how the current methods are adaptable to future new drugs that appear in the market.

Challenges in Detection Approaches for Forensic Science

Challenges in Detection Approaches for Forensic Science
Author: Dr Lynn Dennany
Publsiher: Royal Society of Chemistry
Total Pages: 232
Release: 2021-04-15
ISBN 10: 1839160225
ISBN 13: 9781839160226
Language: EN, FR, DE, ES & NL

Challenges in Detection Approaches for Forensic Science Book Review:

Forensic science combines analytical science with the requirements of law enforcement agencies and legislation. This can often pose challenges within the development of novel analytical methods, particularly with the drive to have more in-field and in-situ applications to facilitate the investigation of criminal cases. This book will explore the specific challenges encountered by forensic scientists and the developments that are being made to address these within the framework of the legislative requirements. It will provide a critical appraisal of the current challenges facing analytical approaches for the detection of forensic evidence and the state of the art technologies used to address these challenges. Providing an excellent combination of current research and how this pertains to forensic investigations, the book will also highlight key obstacles within this ever-changing environment. Aimed at graduates and forensic professionals, this is a unique oversight of the current work being undertaken within the development of analytical methods and also in the interpretation of complex crime scene samples.

Critical Issues in Alcohol and Drugs of Abuse Testing

Critical Issues in Alcohol and Drugs of Abuse Testing
Author: Amitava Dasgupta
Publsiher: Academic Press
Total Pages: 560
Release: 2019-01-10
ISBN 10: 0128156082
ISBN 13: 9780128156087
Language: EN, FR, DE, ES & NL

Critical Issues in Alcohol and Drugs of Abuse Testing Book Review:

Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Neuropharmacology of New Psychoactive Substances NPS

Neuropharmacology of New Psychoactive Substances  NPS
Author: Michael H. Baumann,Richard A. Glennon,Jenny L. Wiley
Publsiher: Springer
Total Pages: 380
Release: 2017-04-13
ISBN 10: 3319524445
ISBN 13: 9783319524443
Language: EN, FR, DE, ES & NL

Neuropharmacology of New Psychoactive Substances NPS Book Review:

Designer drugs, or new psychoactive substances (NPS), are synthetic chemicals that mimic the effects of classic drugs of abuse. There has been an alarming worldwide increase in the abuse of NPS in recent years. NPS are cheap, easy to obtain, and often legally available. In this volume, leading experts summarize the latest studies regarding the molecular mechanisms of action, behavioral effects, and adverse consequences of popular NPS. Specific chapters clarify the differences between various types of NPS, namely: stimulants, cannabinoids and hallucinogens. Thus, this volume broadens our understanding of NPS and provides insight into the rapidly evolving “new drug” phenomenon.

Mass Spectral and GC Data of Drugs Poisons Pesticides Pollutants and Their Metabolites Parts I III

Mass Spectral and GC Data of Drugs  Poisons  Pesticides  Pollutants and Their Metabolites  Parts I III
Author: Karl Pfleger,Hans H. Maurer,Armin A. Weber
Publsiher: Wiley-VCH
Total Pages: 3409
Release: 1992-12-08
ISBN 10: 9783527269891
ISBN 13: 3527269894
Language: EN, FR, DE, ES & NL

Mass Spectral and GC Data of Drugs Poisons Pesticides Pollutants and Their Metabolites Parts I III Book Review:

The new edition of this famous collection: * triples the number of spectra * now includes pesticides and pollutants * also allows identification of doping agents * offers nearly complete coverage of centrally active drugs, designer drugs, registered pesticides, pollutants, organic solvents All the spectra were obtained in the authors' laboratory using GC-MS coupling techniques. As the subtitle (in its new wording) suggests, the collection now reaches far beyond the needs of clinical toxicologists and pharmacologists. Above all, the inclusion of pesticides and pollutants makes this data collection invaluable for environmental chemists, occupational toxicologists and food analysts as well. Unmatched in scope, quality and reliability, this collection is the result of a unique effort. It is indispensable for laboratories in this field all over the world.

Alcohol Drugs Genes and the Clinical Laboratory

Alcohol  Drugs  Genes and the Clinical Laboratory
Author: Amitava Dasgupta
Publsiher: Academic Press
Total Pages: 236
Release: 2016-10-17
ISBN 10: 012809334X
ISBN 13: 9780128093344
Language: EN, FR, DE, ES & NL

Alcohol Drugs Genes and the Clinical Laboratory Book Review:

Alcohol, Drugs, Genes and the Clinical Laboratory provides an overview and quick reference to genetic relationships and clinical laboratory information related to the serious public health issue of alcohol and drug abuse. Written in a clear and concise manner, this book discusses the necessary information for health and safety professionals working in public health to learn about complex issues quickly to better help their patients, employees, and others affected by alcohol and drug abuse. Alcohol, Drugs, Genes and the Clinical Laboratory covers the important aspects of drugs and alcohol abuse including genetic aspects along with laboratory methods for analysis of alcohol and abused drugs with emphasis on false positive test results. The book is helpful to healthcare professionals, such as pathologists who oversee alcohol and drug testing, emergency room physicians, family practice physicians who are first healthcare professionals who identify patients susceptible to drug and alcohol abuse, and psychiatrists involved with drug and alcohol rehabilitation programs. It will also be useful to safety professionals who have to assess individuals for workplace responsibilities, ranging from police and recruitment to occupational safety and occupational medicine and public health officials. Features accessible language for healthcare and safety professionals who are not experts in laboratory procedures Provides examples from clinical and everyday situations Explains how to interpret laboratory results and the latest genetic factors regarding drug and alcohol abuse

The Role of Ultra High Performance Liquid Chromatography with Time of Flight Detection for the Identification of Synthetic Cannabinoids in Seized Drugs

The Role of Ultra High Performance Liquid Chromatography with Time of Flight Detection for the Identification of Synthetic Cannabinoids in Seized Drugs
Author: Anonim
Publsiher: Unknown
Total Pages: 135
Release: 2015
ISBN 10: 1928374650XXX
ISBN 13: OCLC:1051921153
Language: EN, FR, DE, ES & NL

The Role of Ultra High Performance Liquid Chromatography with Time of Flight Detection for the Identification of Synthetic Cannabinoids in Seized Drugs Book Review:

Synthetic Cathinones

Synthetic Cathinones
Author: Jolanta B. Zawilska
Publsiher: Springer
Total Pages: 207
Release: 2018-04-16
ISBN 10: 3319787071
ISBN 13: 9783319787077
Language: EN, FR, DE, ES & NL

Synthetic Cathinones Book Review:

Over the last decade, and particularly during the recent five years, a rapidly increasing number of novel psychoactive substance (NPSs), often marketed as “designer drugs”, “legal highs”, “herbal highs”, “research or intermediate chemicals” and “laboratory reagents”, has appeared on the drug market in an effort to bypass controlled substance legislation. NPSs encompass a wide range of different compounds and drug classes but had been dominated by synthetic cannabinomimetics and psychostimulatory synthetic cathinones, so-called β-keto amphetamines. Compounds from the later class were first detected in Europe in 2004, and since then 103 new cathinones have been identified and reported to the European Monitoring Centre for Drugs and Drug Addiction, with 57 during the last two years. Synthetic cathinones – novel addictive and stimulatory psychoactive substances is the first publication of this kind that provides readers with background on chemical structures, detection, prevalence and motivation of use of the very popular group of NPSs. This book also presents comprehensive overview of the mechanisms of action, pharmacological activity, and main metabolic pathways of synthetic cathinones, followed by a detailed discussion of the acute and chronic toxicity associated with the use of these substances. Written by international experts in the field, this multi-authored book is a valuable reference not only for scientists, clinicians and academics, but also for readers representing different professional background who are involved in educational-prophylactic activities directed to harm reduction of psychoactive compounds.

Pharmacology and Abuse of Cocaine Amphetamines Ecstasy and Related Designer Drugs

Pharmacology and Abuse of Cocaine  Amphetamines  Ecstasy and Related Designer Drugs
Author: Enno Freye
Publsiher: Springer Science & Business Media
Total Pages: 300
Release: 2009-09-21
ISBN 10: 9789048124480
ISBN 13: 9048124484
Language: EN, FR, DE, ES & NL

Pharmacology and Abuse of Cocaine Amphetamines Ecstasy and Related Designer Drugs Book Review:

Finally - a book that covers all aspects of the illicit use of cocaine, amphetamines, ecstasy and/or designer drugs such as GHB, written by two experts in their field. The use of these drugs remains a continuous threat in health and medical care delivery, and this book will be an essential asset to the physician who may have to face the evaluation of patients whose use of these drugs compromises an effective treatment plan for other health issues. The book has been conceived to fill the void in existing physician reference materials, and provides a comprehensive review of the theoretical knowledge and scope of pharmacotherapy in individuals who are hooked on a psychoactive substance. While detailed scientific information is obtainable in other major articles, the book's straightforward format and style, along with its illustrations, will make for easy reading as emphasis is put on information specifically related to drugs that occur most abused in today’s society. The information provided is based on clinical practice rather than pure experimental data, which will give the physician more effective tools useful in their daily practice. Many mechanisms of action of abuse are described in detail and references are provided to direct the reader to further sources for additional information. As a special feature, the book incorporates uncluttered tables and charts, which result in immediate clarification of the mode of action on the central nervous system and the reason for misuse, thus avoiding usual long and fatiguing text in common reference books. The book aims to give the reader a clear and concise plan on what to do when being faced with an overdose situation. A well-organized Table of Contents rapidly leads the reader from general pharmacological issues to the specific overdose syndrome and its management. Additionally, significant emphasis is placed on the practical do's and don’ts for physicians, with special reference to the predictive signs of aberrant drug-related behavior and the identification of the drug diverter by using urine drug screening.

Designer Drugs Directory

Designer Drugs Directory
Author: K. Valter,P. Arrizabalaga
Publsiher: Elsevier
Total Pages: 216
Release: 1998-10-16
ISBN 10: 9780080530321
ISBN 13: 008053032X
Language: EN, FR, DE, ES & NL

Designer Drugs Directory Book Review:

This book is intended to serve as quick reference handbook on so-called designer drugs. These new, mainly synthetic compounds are also often referred to as analogues of controlled substances. This new work provides a unique directory of 104 designer drugs. This class of drugs is rapidly growing in variety and number of compounds. Although identification, toxicology and other properties have been thoroughly investigated, their analogues and derivatives remain poorly documented. This book fills the gap. Data which is available is often contradictory and confused. This directory provides a critical treatment of the subject which is thoroughly indexed including both the subject index and an index listing more that 230 street names of the described designer drugs. Divided into two parts; the first section describes aspects of designer drug manufacture, new abuse trends, sources of information and terminology. The second, descriptive part, classifies the drugs into ten main categories according to their chemical structure and prevalent pharmacological action. A separate chapter is devoted to each category, followed by a set of corresponding data sheets, street names and eventual synonyms, Toxicological data, short notes on the history of drugs as well as the most pertinent bibliographic references are included.

Improving and Accelerating Therapeutic Development for Nervous System Disorders

Improving and Accelerating Therapeutic Development for Nervous System Disorders
Author: Institute of Medicine,Board on Health Sciences Policy,Forum on Neuroscience and Nervous System Disorders
Publsiher: National Academies Press
Total Pages: 118
Release: 2014-02-06
ISBN 10: 0309292492
ISBN 13: 9780309292498
Language: EN, FR, DE, ES & NL

Improving and Accelerating Therapeutic Development for Nervous System Disorders Book Review:

Improving and Accelerating Therapeutic Development for Nervous System Disorders is the summary of a workshop convened by the IOM Forum on Neuroscience and Nervous System Disorders to examine opportunities to accelerate early phases of drug development for nervous system drug discovery. Workshop participants discussed challenges in neuroscience research for enabling faster entry of potential treatments into first-in-human trials, explored how new and emerging tools and technologies may improve the efficiency of research, and considered mechanisms to facilitate a more effective and efficient development pipeline. There are several challenges to the current drug development pipeline for nervous system disorders. The fundamental etiology and pathophysiology of many nervous system disorders are unknown and the brain is inaccessible to study, making it difficult to develop accurate models. Patient heterogeneity is high, disease pathology can occur years to decades before becoming clinically apparent, and diagnostic and treatment biomarkers are lacking. In addition, the lack of validated targets, limitations related to the predictive validity of animal models - the extent to which the model predicts clinical efficacy - and regulatory barriers can also impede translation and drug development for nervous system disorders. Improving and Accelerating Therapeutic Development for Nervous System Disorders identifies avenues for moving directly from cellular models to human trials, minimizing the need for animal models to test efficacy, and discusses the potential benefits and risks of such an approach. This report is a timely discussion of opportunities to improve early drug development with a focus toward preclinical trials.

Hair Analysis in Clinical and Forensic Toxicology

Hair Analysis in Clinical and Forensic Toxicology
Author: Pascal Kintz,Alberto Salomone,Marco Vincenti
Publsiher: Academic Press
Total Pages: 392
Release: 2015-06-25
ISBN 10: 0128017104
ISBN 13: 9780128017104
Language: EN, FR, DE, ES & NL

Hair Analysis in Clinical and Forensic Toxicology Book Review:

Hair Analysis in Clinical and Forensic Toxicology is an essential reference for toxicologists working with, and researching, hair analysis. The text presents a review of the most up-to-date analytical methods in toxicological hair analysis, along with state-of-the-art developments in the areas of hair physiology, sampling, and pre-treatments, as well as discussions of fundamental issues, applications, and results interpretation. Topics addressed include the diagnosis of chronic excessive alcohol drinking by means of ethyl glucuronide (EtG) and fatty acid ethyl esters (FAEE), the early detection of new psychoactive substances, including designer drugs, the development of novel approaches to screening tests based on mass spectrometry, and the detection of prenatal exposure to psychoactive substances from the analysis of newborn hair. Unites an international team of leading experts to provide an update on the cutting-edge advances in the toxicological analysis of hair Demonstrates toxicological techniques relating to a variety of scenarios and exposure types Ideal resource for the further study of the psychoactive substances, drug-facilitated crimes, ecotoxicology, analytical toxicology, occupational toxicology, toxicity testing, and forensic toxicology Includes detailed instructions for the collection, preparation, and handling of hair, and how to best interpret results

Advances in Forensic Applications of Mass Spectrometry

Advances in Forensic Applications of Mass Spectrometry
Author: Jehuda Yinon
Publsiher: CRC Press
Total Pages: 279
Release: 2003-12-29
ISBN 10: 9780203998281
ISBN 13: 0203998286
Language: EN, FR, DE, ES & NL

Advances in Forensic Applications of Mass Spectrometry Book Review:

Recent developments in analytical instrumentation have had an enormous influence on forensic analysis. The mass spectrometer is now an integral part of every forensic laboratory, resulting in greater analytical accuracy, more reliable identification, and lower detection limits. As the instrumental method of choice among forensic analysts, the mass spectrometer continues to pave the way for innovative applications in forensic analysis. Exploring the latest developments in the field, Advances in Forensic Applications of Mass Spectrometry provides a comprehensive reference guide to forensic applications using modern mass spectrometry techniques. The book features methods developed from advanced instrumentation, drug detection and toxicological analysis, and methodology of applications of stable isotope ratios. The final chapters present approaches for identifying accelerants in fire debris and procedures for analyzing explosives in post-blast residues. Jehuda Yinon, Ph.D., is one of the top forensic chemists in the world. As the editor of this authoritative volume, he compiles the knowledge of leading experts to demonstrate the use of novel mass spectrometry techniques in a vast range of forensic applications.

Forensic Toxicology

Forensic Toxicology
Author: Max M. Houck
Publsiher: Academic Press
Total Pages: 418
Release: 2018-01-02
ISBN 10: 0128008180
ISBN 13: 9780128008188
Language: EN, FR, DE, ES & NL

Forensic Toxicology Book Review:

Forensic Toxicology, the latest release in the Advanced Forensic Science Series that grew out of recommendations from the 2009 NAS Report, Strengthening Forensic Science: A Path Forward will serve as a graduate level text for those studying and teaching forensic toxicology. It is also an excellent reference for the forensic practitioner’s library or for use in their casework. Coverage includes a wide variety of methods used, along with pharmacology and drugs and professional issues they may encounter. Edited by a world-renowned, leading forensic expert, this updated edition is a long overdue solution for the forensic science community. Provides basic principles of forensic science and an overview of forensic toxicology Contains information on a wide variety of methods Covers pharmacology and drugs, matrices and interpretation Includes a section on professional issues, such as crime scene to court, lab reports, health and safety, post-mortem and drug facilitated crimes Incorporates effective pedagogy, key terms, review questions, discussion questions and additional reading suggestions

Toxicology Cases for the Clinical and Forensic Laboratory

Toxicology Cases for the Clinical and Forensic Laboratory
Author: Hema Ketha,Uttam Garg
Publsiher: Academic Press
Total Pages: 540
Release: 2020-06-20
ISBN 10: 0128163739
ISBN 13: 9780128163733
Language: EN, FR, DE, ES & NL

Toxicology Cases for the Clinical and Forensic Laboratory Book Review:

Toxicology Cases for the Clinical and Forensic Laboratory brings together carefully selected case studies to teach important principles relating to drug and toxin exposures. Each case study includes contemporary clinical and forensic toxicologist studies that include a comprehensive analytical and clinical approach to patient management and address overdoses from designer drugs, to NSAIDS, to opioids, to stimulants. These cases present a comprehensive, analytical and clinical approach to managing a drug overdose. This is a must-have reference for clinical and forensic laboratory scientists, along with toxicology and pathology residents who need to know aspects of both. Brings together expert cases encompassing analytical toxicology, clinical medicine and basic science in a consolidated format Presents unique and challenging cases in clinical laboratories contributed by experts in the field Consolidated format that make concepts in toxicology easy to learn and teach Key learning points highlighted with multiple choice questions

Interpretation of MS MS Mass Spectra of Drugs and Pesticides

Interpretation of MS MS Mass Spectra of Drugs and Pesticides
Author: Wilfried M. A. Niessen,Ricardo A. Correa C.
Publsiher: John Wiley & Sons
Total Pages: 416
Release: 2017-01-03
ISBN 10: 111929424X
ISBN 13: 9781119294245
Language: EN, FR, DE, ES & NL

Interpretation of MS MS Mass Spectra of Drugs and Pesticides Book Review:

Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds, drugs of abuse and designer drugs, antimicrobials, among many others Covers general fragmentation rule as well as specific fragmentation pathways for many chemical functional groups Gives an introduction to MS technology, mass spectral terminology, information contained in mass spectra, and to the identification strategies used for different types of unknowns

Essentials of Autopsy Practice

Essentials of Autopsy Practice
Author: Guy N. Rutty
Publsiher: Springer
Total Pages: 182
Release: 2017-02-14
ISBN 10: 3319469975
ISBN 13: 9783319469973
Language: EN, FR, DE, ES & NL

Essentials of Autopsy Practice Book Review:

This book covers topical subjects within the field of death investigation, where changes in practice have recently occurred. As the area of dating of wounds has changed since the subject was addressed in a previous volume, this subject is revisited for the first time. The remaining subjects covered in this volume embrace the multi-disciplinary approach required for death investigation, and address advances in the field of forensic radiology imaging, pathology, and toxicology. There is also a chapter on cardiopulmonary resuscitation which explains clinical processes and procedures that may occur to an individual immediately before death that may have a bearing on the subsequent autopsy findings. Essentials of Autopsy Practice: Reviews, Updates and Advances is an educational and practical resource aimed at trainees and consultants, generalists and specialists, and the new multi-disciplinary team alike.

Forensic Drug Analysis

Forensic Drug Analysis
Author: Future Science Ltd
Publsiher: Unknown
Total Pages: 125
Release: 2013
ISBN 10: 9781909453364
ISBN 13: 1909453366
Language: EN, FR, DE, ES & NL

Forensic Drug Analysis Book Review:

Issues in Drug Management Toxicology Monitoring Resistance and Safety 2011 Edition

Issues in Drug Management  Toxicology  Monitoring  Resistance  and Safety  2011 Edition
Author: Anonim
Publsiher: ScholarlyEditions
Total Pages: 363
Release: 2012-01-09
ISBN 10: 1464967091
ISBN 13: 9781464967092
Language: EN, FR, DE, ES & NL

Issues in Drug Management Toxicology Monitoring Resistance and Safety 2011 Edition Book Review:

Issues in Drug Management, Toxicology, Monitoring, Resistance, and Safety: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Drug Management, Toxicology, Monitoring, Resistance, and Safety. The editors have built Issues in Drug Management, Toxicology, Monitoring, Resistance, and Safety: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Drug Management, Toxicology, Monitoring, Resistance, and Safety in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Drug Management, Toxicology, Monitoring, Resistance, and Safety: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.